BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0150.p (421 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DCK3.1 B1DCK3_9BACL Sensor protein EC=2.7.13.3 521 e-146 A6TPN7.1 A6TPN7_ALKMQ Sensor protein EC=2.7.13.3 489 e-136 A9U6U0.1 A9U6U0_PHYPA Sensory histidine protein kinase 448 e-124 A5N1L6.1 A5N1L6_CLOK5 Sensor protein EC=2.7.13.3 372 e-101 B9E5D0.1 B9E5D0_CLOK1 Sensor protein EC=2.7.13.3 372 e-101 >B1DCK3.1 B1DCK3_9BACL Sensor protein EC=2.7.13.3 Length = 430 Score = 521 bits (1342), Expect = e-146, Method: Compositional matrix adjust. Identities = 259/429 (60%), Positives = 332/429 (77%), Gaps = 11/429 (2%) Query: 1 MFKKLRNRFLIVNLTTISVIMLIAFASIYVIMYLNVQNDINMNLHRIADY--QQKGP--- 55 MF +LRNRFLIVN+ IS IM++AF+SIY I Y N + +N +L +I+++ +Q+GP Sbjct: 1 MFNRLRNRFLIVNMVIISFIMILAFSSIYTITYQNNRKTMNEDLIQISEFYRKQEGPEGG 60 Query: 56 ---GDAGHPGSADGIPPKENRPMEGGNPPPERSISFTVTTDASGNLKDKDSKFTMDDEFY 112 G G G D + P + M+ G PPPERS+SF +TTDA N+ + DS+F MD +FY Sbjct: 61 KYSGGGGGHGRGDMMVP--DGKMKAG-PPPERSVSFALTTDADWNITNTDSRFDMDSDFY 117 Query: 113 TAALKEALSIGKDIGRFTLDDSRWIFTVKHTGEGKVIVFLDITAQQKILTNLIYTFTAVG 172 T A+K A S D G F LD +RW + V+ EG +VFLD+T Q + L L+YTF AVG Sbjct: 118 TLAIKAASSGDSDRGEFNLDGNRWAYDVQQVMEGYSVVFLDVTNQHQFLMTLLYTFLAVG 177 Query: 173 LLMLIILYFTSRFFANRSIAPVREAFDKQKQFIADASHELKTPLTIINTNADVLLSNSGD 232 +MLI++YFTSR+FANRSIAPV+EAFDKQK+FIADASHEL+TPL +INTNADVLLSN+ D Sbjct: 178 FIMLIVIYFTSRYFANRSIAPVKEAFDKQKRFIADASHELRTPLAVINTNADVLLSNNDD 237 Query: 233 TIGNQAKWLQYIKSETERMTRLTNDLLYLTEMDDSRTGMMHSRFNISEAVENIILTMEAV 292 I NQ KWL +IKSETERM LT+DLLYLT+MDD+R ++ + FN+SEAVE++ILT+EAV Sbjct: 238 LIRNQEKWLHHIKSETERMRTLTSDLLYLTQMDDARENVIFAPFNLSEAVESVILTLEAV 297 Query: 293 IFEKHISFDYDIQPELTVQGNSEQIKQVVMILLDNAVKYTNPKGAVAITLKKQNNDVLLS 352 IFEK I+ YDI PEL++ GN EQ+KQV +ILLDNA+KYTN KG + +TLKK ++V+L+ Sbjct: 298 IFEKDIALSYDISPELSINGNVEQMKQVALILLDNAIKYTNTKGKIDLTLKKHGSEVVLN 357 Query: 353 VSNTGEGIAAEHLTRIFDRFYRTDTSRARQQGGYGLGLAIAKSIVEQHKGRIYAKSVVGE 412 V+N+GEGI EHL +IFDRFYR D SR+R+ GGYGLGLAIAK+IVEQHKG+I+AKSV GE Sbjct: 358 VTNSGEGIPPEHLGKIFDRFYRADASRSRKHGGYGLGLAIAKAIVEQHKGKIHAKSVPGE 417 Query: 413 STTFYVQLP 421 +T+F VQLP Sbjct: 418 TTSFSVQLP 426 >A6TPN7.1 A6TPN7_ALKMQ Sensor protein EC=2.7.13.3 Length = 424 Score = 489 bits (1260), Expect = e-136, Method: Compositional matrix adjust. Identities = 246/423 (58%), Positives = 312/423 (73%), Gaps = 5/423 (1%) Query: 1 MFKKLRNRFLIVNLTTISVIMLIAFASIYVIMYLNVQNDINMNLHRIADYQQKGPGDAGH 60 MFK+LR++FLI+NL ISV+MLIAF SIY+I Y NV +I M LHRI+D+ ++ Sbjct: 1 MFKQLRDKFLILNLIIISVMMLIAFTSIYLITYNNVHRNIQMELHRISDFSRRVNERPNQ 60 Query: 61 P--GSADGIPPKENRPMEGGNPPPERSISFTVTTDASGNLKDKDSKFTMDDEFYTAALKE 118 P S + P E P++ P E S+SFT+ TD+ GNL + S FT++D FY A Sbjct: 61 PPRDSDTEVIPSEMAPVQR---PREPSVSFTLVTDSEGNLLEISSIFTIEDAFYERAKNS 117 Query: 119 ALSIGKDIGRFTLDDSRWIFTVKHTGEGKVIVFLDITAQQKILTNLIYTFTAVGLLMLII 178 ALS D G L+D W F +K + IVFLDIT+QQ LTNLIYTF V +MLI+ Sbjct: 118 ALSQNTDSGSLKLEDQYWRFVIKPHFDDYRIVFLDITSQQGFLTNLIYTFFMVAFIMLIV 177 Query: 179 LYFTSRFFANRSIAPVREAFDKQKQFIADASHELKTPLTIINTNADVLLSNSGDTIGNQA 238 ++F SRFFAN+SI P+ EAFDKQKQFIADASHELKTPLTII+TN DVLLS+ D + + Sbjct: 178 IFFISRFFANKSIKPIEEAFDKQKQFIADASHELKTPLTIIHTNIDVLLSSGEDQVNGPS 237 Query: 239 KWLQYIKSETERMTRLTNDLLYLTEMDDSRTGMMHSRFNISEAVENIILTMEAVIFEKHI 298 KWL YIKSETERMT+L NDLLYLT++D S M+ + FN+S+AVENIILTM+AVI+E ++ Sbjct: 238 KWLYYIKSETERMTKLINDLLYLTQVDYSDVKMIVTSFNLSDAVENIILTMDAVIYENNL 297 Query: 299 SFDYDIQPELTVQGNSEQIKQVVMILLDNAVKYTNPKGAVAITLKKQNNDVLLSVSNTGE 358 S DY ++P L G+ EQI+QVVMILLDNAVKYT+ KG + I+LKK ++ ++LSV+NT E Sbjct: 298 SLDYMVEPNLISLGSREQIQQVVMILLDNAVKYTDSKGIITISLKKYHSSLVLSVTNTSE 357 Query: 359 GIAAEHLTRIFDRFYRTDTSRARQQGGYGLGLAIAKSIVEQHKGRIYAKSVVGESTTFYV 418 GI EH+ RIF RFYR D SRAR+ GGYGLGLAIAK+I++QH G+IY KS++ ESTTF V Sbjct: 358 GITQEHIDRIFHRFYRIDQSRARKSGGYGLGLAIAKTIIQQHGGKIYVKSILNESTTFTV 417 Query: 419 QLP 421 +LP Sbjct: 418 ELP 420 >A9U6U0.1 A9U6U0_PHYPA Sensory histidine protein kinase Length = 315 Score = 448 bits (1152), Expect = e-124, Method: Compositional matrix adjust. Identities = 218/314 (69%), Positives = 260/314 (82%) Query: 107 MDDEFYTAALKEALSIGKDIGRFTLDDSRWIFTVKHTGEGKVIVFLDITAQQKILTNLIY 166 M+D FY A +EA S +FTL+ +RW + V+ T G IVFLD+TAQ KI+TNLIY Sbjct: 1 MEDTFYETAKEEAASKPVRNAQFTLEGTRWAYGVQQTPSGYSIVFLDVTAQLKIITNLIY 60 Query: 167 TFTAVGLLMLIILYFTSRFFANRSIAPVREAFDKQKQFIADASHELKTPLTIINTNADVL 226 TF+ V L+ML ++Y TSR+FANRSI PVREAFDKQKQFIADASHELKTPL +INTNADVL Sbjct: 61 TFSIVALVMLAVIYLTSRYFANRSIEPVREAFDKQKQFIADASHELKTPLAVINTNADVL 120 Query: 227 LSNSGDTIGNQAKWLQYIKSETERMTRLTNDLLYLTEMDDSRTGMMHSRFNISEAVENII 286 L+NS +TI +Q+KWLQ+IKSETERM LTNDLLYLT+MDD+R M+ F++SEAVE++I Sbjct: 121 LANSDETIRSQSKWLQHIKSETERMKTLTNDLLYLTQMDDARGLMIFVPFDLSEAVESVI 180 Query: 287 LTMEAVIFEKHISFDYDIQPELTVQGNSEQIKQVVMILLDNAVKYTNPKGAVAITLKKQN 346 LTMEAVIFEK +SF YDI+P LT+ G+SEQIKQVVMILLDNAVKYTNP+G++ ++LKKQ+ Sbjct: 181 LTMEAVIFEKELSFTYDIEPRLTLTGSSEQIKQVVMILLDNAVKYTNPRGSIHLSLKKQH 240 Query: 347 NDVLLSVSNTGEGIAAEHLTRIFDRFYRTDTSRARQQGGYGLGLAIAKSIVEQHKGRIYA 406 N +LL V+NTGEGIA EHL IFDRFYR D SR+R+ GGYGLGLAIAKSIVEQHKG+I Sbjct: 241 NHLLLRVTNTGEGIAPEHLDNIFDRFYRVDASRSRKHGGYGLGLAIAKSIVEQHKGKISV 300 Query: 407 KSVVGESTTFYVQL 420 KSV E TTF VQL Sbjct: 301 KSVPNEKTTFDVQL 314 >A5N1L6.1 A5N1L6_CLOK5 Sensor protein EC=2.7.13.3 Length = 437 Score = 372 bits (955), Expect = e-101, Method: Compositional matrix adjust. Identities = 198/438 (45%), Positives = 276/438 (63%), Gaps = 32/438 (7%) Query: 1 MFKKLRNRFLIVNLTTISVIMLIAFASIYVIMYLNVQNDINMNLHRIADYQQKGPGDAGH 60 MFK+LRN+FLI+N++ ISV+M+ AFA IY I Y ND+ M + Q K Sbjct: 1 MFKRLRNKFLILNMSIISVMMITAFAVIYTITY----NDMQM------ENQNKLLSLPVI 50 Query: 61 PGSADGIPPKENRPMEGG-----NPPPERSISFTVTTDASGNLKDKDSKFTMDDEFYTAA 115 ++ PPK N + G N P + S+SF++ D+ G + D DS M DE Y A Sbjct: 51 KLESNSNPPKTNGSVSAGLHVIRNIPSDYSLSFSIRVDSDGKVSDIDSYIDMSDENYHKA 110 Query: 116 LKEALSIGKDIGRFTLDDSRWIFT-----------------VKHTGEGKVIVFLDITAQQ 158 + A S K+ LD W +T V T +G I FLD+T Sbjct: 111 AELAWSNKKNNSTINLDGKLWEYTLSPIVENHIIFQNGQQSVNTTDKGYDIKFLDVTDTH 170 Query: 159 KILTNLIYTFTAVGLLMLIILYFTSRFFANRSIAPVREAFDKQKQFIADASHELKTPLTI 218 K L L+ TF VG++MLI+++ S +FANR+I P+ E ++KQKQ +ADASHELKTPL I Sbjct: 171 KTLGELLATFIVVGIVMLIVIFVISLYFANRAIKPIAEVWEKQKQLVADASHELKTPLAI 230 Query: 219 INTNADVLLSNSGDTIGNQAKWLQYIKSETERMTRLTNDLLYLTEMDDSRTGMMHSRFNI 278 IN N+D LL+ +TI +Q KWL YIK+E RMT+L NDLLYL + +++ ++S +I Sbjct: 231 INANSDALLAVQEETIKSQKKWLHYIKAEICRMTKLINDLLYLAKTENTSVRRIYSSLDI 290 Query: 279 SEAVENIILTMEAVIFEKHISFDYDIQPELTVQGNSEQIKQVVMILLDNAVKYTNPKGAV 338 S V N++L+MEA+ FEK I F + ++ ++ V+G+ EQIKQVVMILLDNA+KYT+ KG + Sbjct: 291 SSIVNNVVLSMEAIAFEKDIKFSHKVEQDIMVKGDPEQIKQVVMILLDNAIKYTDEKGYI 350 Query: 339 AITLKKQNNDVLLSVSNTGEGIAAEHLTRIFDRFYRTDTSRARQQGGYGLGLAIAKSIVE 398 I+LKK ++ S+ N+G+GI+ + L ++FDRFYR D SR + GGYGLGL+IAK+I++ Sbjct: 351 NISLKKTKRYIVFSIKNSGKGISKQDLPKLFDRFYRVDPSRTHENGGYGLGLSIAKAIID 410 Query: 399 QHKGRIYAKSVVGESTTF 416 GRIYA+SV ESTTF Sbjct: 411 SLGGRIYAESVENESTTF 428 >B9E5D0.1 B9E5D0_CLOK1 Sensor protein EC=2.7.13.3 Length = 441 Score = 372 bits (954), Expect = e-101, Method: Compositional matrix adjust. Identities = 198/438 (45%), Positives = 276/438 (63%), Gaps = 32/438 (7%) Query: 1 MFKKLRNRFLIVNLTTISVIMLIAFASIYVIMYLNVQNDINMNLHRIADYQQKGPGDAGH 60 MFK+LRN+FLI+N++ ISV+M+ AFA IY I Y ND+ M + Q K Sbjct: 5 MFKRLRNKFLILNMSIISVMMITAFAVIYTITY----NDMQM------ENQNKLLSLPVI 54 Query: 61 PGSADGIPPKENRPMEGG-----NPPPERSISFTVTTDASGNLKDKDSKFTMDDEFYTAA 115 ++ PPK N + G N P + S+SF++ D+ G + D DS M DE Y A Sbjct: 55 KLESNSNPPKTNGSVSAGLHVIRNIPSDYSLSFSIRVDSDGKVSDIDSYIDMSDENYHKA 114 Query: 116 LKEALSIGKDIGRFTLDDSRWIFT-----------------VKHTGEGKVIVFLDITAQQ 158 + A S K+ LD W +T V T +G I FLD+T Sbjct: 115 AELAWSNKKNNSTINLDGKLWEYTLSPIVENHIIFQNGQQSVNTTDKGYDIKFLDVTDTH 174 Query: 159 KILTNLIYTFTAVGLLMLIILYFTSRFFANRSIAPVREAFDKQKQFIADASHELKTPLTI 218 K L L+ TF VG++MLI+++ S +FANR+I P+ E ++KQKQ +ADASHELKTPL I Sbjct: 175 KTLGELLATFIVVGIVMLIVIFVISLYFANRAIKPIAEVWEKQKQLVADASHELKTPLAI 234 Query: 219 INTNADVLLSNSGDTIGNQAKWLQYIKSETERMTRLTNDLLYLTEMDDSRTGMMHSRFNI 278 IN N+D LL+ +TI +Q KWL YIK+E RMT+L NDLLYL + +++ ++S +I Sbjct: 235 INANSDALLAVQEETIKSQKKWLHYIKAEICRMTKLINDLLYLAKTENTSVRRIYSSLDI 294 Query: 279 SEAVENIILTMEAVIFEKHISFDYDIQPELTVQGNSEQIKQVVMILLDNAVKYTNPKGAV 338 S V N++L+MEA+ FEK I F + ++ ++ V+G+ EQIKQVVMILLDNA+KYT+ KG + Sbjct: 295 SSIVNNVVLSMEAIAFEKDIKFSHKVEQDIMVKGDPEQIKQVVMILLDNAIKYTDEKGYI 354 Query: 339 AITLKKQNNDVLLSVSNTGEGIAAEHLTRIFDRFYRTDTSRARQQGGYGLGLAIAKSIVE 398 I+LKK ++ S+ N+G+GI+ + L ++FDRFYR D SR + GGYGLGL+IAK+I++ Sbjct: 355 NISLKKTKRYIVFSIKNSGKGISKQDLPKLFDRFYRVDPSRTHENGGYGLGLSIAKAIID 414 Query: 399 QHKGRIYAKSVVGESTTF 416 GRIYA+SV ESTTF Sbjct: 415 SLGGRIYAESVENESTTF 432 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,409,544,210 Number of extensions: 101321105 Number of successful extensions: 383143 Number of sequences better than 1.0e-05: 29876 Number of HSP's gapped: 340720 Number of HSP's successfully gapped: 29991 Length of query: 421 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 283 Effective length of database: 1,760,596,133 Effective search space: 498248705639 Effective search space used: 498248705639 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)