BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0149.p (219 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DCQ6.1 B1DCQ6_9BACL Two component transcriptional regulator, w... 395 e-108 C2Q351.1 C2Q351_BACCE DNA-binding response regulator 269 1e-70 Q18C50.1 Q18C50_CLOD6 Two-component response regulator 266 9e-70 C2HDH8.1 C2HDH8_ENTFC Response regulator 266 1e-69 C2H1N6.1 C2H1N6_ENTFA Response regulator 262 1e-68 >B1DCQ6.1 B1DCQ6_9BACL Two component transcriptional regulator, winged helix family Length = 223 Score = 395 bits (1015), Expect = e-108, Method: Compositional matrix adjust. Identities = 187/219 (85%), Positives = 204/219 (93%) Query: 1 MIVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWC 60 MI+EDDEKIRRIVAD L KW+YE +++SFD V+ +F A+QPHLVLLDVNLPV+DGFYWC Sbjct: 5 MIIEDDEKIRRIVADALRKWQYEAIELTSFDNVLGEFEAAQPHLVLLDVNLPVFDGFYWC 64 Query: 61 QQIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTYQD 120 QQIR SKVPIIF+SSRNQNMDVIMAINMG DDFVQKPFDLGVLVAKVSALLRRNYTYQD Sbjct: 65 QQIRMASKVPIIFISSRNQNMDVIMAINMGGDDFVQKPFDLGVLVAKVSALLRRNYTYQD 124 Query: 121 ESLQMAHRQLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQVLWSDE 180 ++LQM+HRQL FHLSNSSV+Y QTAELSRNEFIILQTMMR+IGKIVSRD LMQVLW+DE Sbjct: 125 DNLQMSHRQLVFHLSNSSVQYGDQTAELSRNEFIILQTMMRSIGKIVSRDDLMQVLWNDE 184 Query: 181 QFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYIIE 219 QFIDDNTLTVNVNRLRRKIA+LGLEDFI TRKGMGYIIE Sbjct: 185 QFIDDNTLTVNVNRLRRKIAVLGLEDFIATRKGMGYIIE 223 >C2Q351.1 C2Q351_BACCE DNA-binding response regulator Length = 223 Score = 269 bits (688), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 126/219 (57%), Positives = 165/219 (75%), Gaps = 1/219 (0%) Query: 1 MIVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWC 60 ++VED+ IR VAD L KW +EV ++F+ +++DF A P LVLLD+NLP +DGFYWC Sbjct: 4 LLVEDEPTIRETVADELGKWGFEVWSSTNFEHILNDFLAQSPQLVLLDINLPYFDGFYWC 63 Query: 61 QQIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTY-Q 119 ++IR VSKVPIIFLSSR+ MD++MA+NMG DDFVQKPF VLVAK+ AL+RR Y+Y Q Sbjct: 64 RKIREVSKVPIIFLSSRDNPMDMVMAMNMGGDDFVQKPFYTDVLVAKIQALMRRTYSYTQ 123 Query: 120 DESLQMAHRQLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQVLWSD 179 E+ + H + +L V Y Q EL++NEF ILQ +M+NIG IVSRD++M+ LW + Sbjct: 124 TETNVVEHEGVVLNLQTGEVTYHNQILELTKNEFKILQMLMQNIGAIVSRDNIMRKLWEN 183 Query: 180 EQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYII 218 E F+DDNTLTVNV R+R+K+A LG E+FI T+KG GYII Sbjct: 184 ESFVDDNTLTVNVARVRKKLAELGKEEFIHTKKGQGYII 222 >Q18C50.1 Q18C50_CLOD6 Two-component response regulator Length = 224 Score = 266 bits (680), Expect = 9e-70, Method: Compositional matrix adjust. Identities = 120/219 (54%), Positives = 167/219 (76%), Gaps = 1/219 (0%) Query: 1 MIVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWC 60 M+VEDD ++ I+A L+KW ++V Q+ + + ++++F P LVLLD+NLP YDGF+WC Sbjct: 5 MVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNYNPELVLLDINLPFYDGFHWC 64 Query: 61 QQIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTYQD 120 +IR +SKVPIIF+SSRN NMDVIM +N+GADD++QKPF + VLVAKV+ALLRR Y + D Sbjct: 65 NEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKPFSVDVLVAKVNALLRRTYNFVD 124 Query: 121 -ESLQMAHRQLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQVLWSD 179 S Q+ H +T LS +++ YE T EL++NE IL +M+ G+IVSR+ LM+ LW + Sbjct: 125 NNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKILHELMKYKGQIVSRNKLMKKLWDN 184 Query: 180 EQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYII 218 + F+DDNTLTVNVNR+R K+ +GLEDFI T++G+GYII Sbjct: 185 DWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRGLGYII 223 >C2HDH8.1 C2HDH8_ENTFC Response regulator Length = 244 Score = 266 bits (679), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 121/219 (55%), Positives = 170/219 (77%), Gaps = 1/219 (0%) Query: 1 MIVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWC 60 M+VED+E IR+++ + L KW++E + F+QV DF +P LVLLD+NLPV DG+YWC Sbjct: 25 MVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFEREEPQLVLLDINLPVLDGYYWC 84 Query: 61 QQIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTYQD 120 Q+IR VSKVPIIF+SSRN NMD+IMA+NMGADDFV KPF + VL+AK++ALLRR+Y Y + Sbjct: 85 QKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKPFQIDVLIAKINALLRRSYNYTE 144 Query: 121 ESLQ-MAHRQLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQVLWSD 179 S + M+H +T ++ N S+E G+ +LS+NE+ +L +M++ GKI+SR+ L++ LW D Sbjct: 145 LSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRLLFILMKHNGKILSREKLLRALWDD 204 Query: 180 EQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYII 218 E+F+DDNTLTVN+NRLRRKI G++ +I T+ G GYI+ Sbjct: 205 ERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVGQGYIV 243 >C2H1N6.1 C2H1N6_ENTFA Response regulator Length = 224 Score = 262 bits (670), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 116/219 (52%), Positives = 169/219 (77%), Gaps = 1/219 (0%) Query: 1 MIVEDDEKIRRIVADTLSKWKYEVTQVSSFDQVMDDFTASQPHLVLLDVNLPVYDGFYWC 60 MIVED+ IR ++++ L KW++E + F+ V+DDF P LVL+D+NLPVYDG+YWC Sbjct: 5 MIVEDETTIRELISEELQKWQFETIGTTDFNDVLDDFQEENPQLVLMDINLPVYDGYYWC 64 Query: 61 QQIRAVSKVPIIFLSSRNQNMDVIMAINMGADDFVQKPFDLGVLVAKVSALLRRNYTYQD 120 Q+IR VSKVPIIF+SSR+ NMD+IMA+NMGADDFV KPF + VL+AK++ALLRR+Y Y D Sbjct: 65 QKIREVSKVPIIFISSRSTNMDMIMAMNMGADDFVTKPFQIDVLIAKINALLRRSYNYSD 124 Query: 121 -ESLQMAHRQLTFHLSNSSVEYEGQTAELSRNEFIILQTMMRNIGKIVSRDSLMQVLWSD 179 +S ++H +T ++ N +E +G+ +LS+NE+ +L +M+ GKI++R+ L++ LW D Sbjct: 125 TDSEVLSHNGITLNVDNGRMEIKGEMIDLSKNEYRLLYLLMKKHGKILTREKLLRALWDD 184 Query: 180 EQFIDDNTLTVNVNRLRRKIALLGLEDFIVTRKGMGYII 218 E+F+DDNTLTVN+NRLR+KI G+ +I T+ G+GY++ Sbjct: 185 ERFVDDNTLTVNINRLRKKIEQAGIAGYIETKVGVGYMV 223 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.136 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,155,968,560 Number of extensions: 41696136 Number of successful extensions: 184457 Number of sequences better than 1.0e-05: 20416 Number of HSP's gapped: 171643 Number of HSP's successfully gapped: 20453 Length of query: 219 Length of database: 3,060,696,203 Length adjustment: 130 Effective length of query: 89 Effective length of database: 1,835,964,253 Effective search space: 163400818517 Effective search space used: 163400818517 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 128 (53.9 bits)