BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0139.p (224 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0ZCX5.1 C0ZCX5_BREBN Putative transcriptional regulator 324 3e-87 C1RD76.1 C1RD76_9ACTO Transcriptional regulator, TetR family 114 9e-24 C4EFD7.1 C4EFD7_STRRS Transcriptional regulator, TetR family 108 3e-22 A8L7B4.1 A8L7B4_FRASN Transcriptional regulator, TetR family 97 9e-19 A7HWI0.1 A7HWI0_PARL1 Transcriptional regulator, TetR family 91 6e-17 >C0ZCX5.1 C0ZCX5_BREBN Putative transcriptional regulator Length = 218 Score = 324 bits (831), Expect = 3e-87, Method: Compositional matrix adjust. Identities = 152/214 (71%), Positives = 177/214 (82%) Query: 6 ISNEDKPSPSTGRVLKTYQEARLQNTENLRKLVVDAAAAILQEEGPEAVTVRRVSQKMGC 65 +S++D S + RVLKTYQEARLQN ENLRKLVVDAAA ILQEEGPEAVTVR+VSQKMGC Sbjct: 1 MSDQDISSNANSRVLKTYQEARLQNLENLRKLVVDAAATILQEEGPEAVTVRKVSQKMGC 60 Query: 66 STKIIYSLFVNKEGLAQQLYLEGCKLLAQRFEEVPPSSDPLQHLLDLGEAFWQFGQEYTS 125 STKIIY+LFVNKEGLAQQLYL+GCKLLA E P ++DP QHL +LGEAFWQFGQ Y+S Sbjct: 61 STKIIYNLFVNKEGLAQQLYLDGCKLLAYELERTPQAADPAQHLQNLGEAFWQFGQRYSS 120 Query: 126 YYKLMFGGAFAEFKPDAESMQGTMTAMSRLLILISTAQQQGQISDKEETQTIVSTIWASL 185 YYKLMFGGAFA+FKPD ES+ GT+TAM +LL +IS AQQQG I + +T+ ++ WASL Sbjct: 121 YYKLMFGGAFADFKPDEESLNGTVTAMRQLLTVISNAQQQGLIPGQYDTELVIRVFWASL 180 Query: 186 HGVIHLYMGGFLGDADAAHTVYKQTIVLLSRSLF 219 HGVIHLYMGG LGD +AH VY+QT+ L+ SL Sbjct: 181 HGVIHLYMGGHLGDVQSAHAVYRQTLSLIVSSLL 214 >C1RD76.1 C1RD76_9ACTO Transcriptional regulator, TetR family Length = 230 Score = 114 bits (284), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 63/185 (34%), Positives = 93/185 (50%), Gaps = 6/185 (3%) Query: 23 YQEARLQNTENLRKLVVDAAAAILQEEGPEAVTVRRVSQKMGCSTKIIYSLFVNKEGLAQ 82 Y A+ E LR ++D AA +L EGP A+T+RR++ + GCST ++Y F +K+ +A Sbjct: 29 YARAQALGQEVLRASLLDVAAQLLAAEGPAALTMRRIATEAGCSTMVLYKHFGSKDAIAA 88 Query: 83 QLYLEGCKLLAQRFEEVPPSSDPLQHLLDLGEAFWQFGQEYTSYYKLMFGGAFAEFKPDA 142 LYLEG L + + VP DP +HL LG A+ + ++Y +M G + PDA Sbjct: 89 ALYLEGFARLKRHLDAVPRGDDPAEHLAALGRAYRENALAEPNFYDVMHGPGIPGYTPDA 148 Query: 143 ESMQGTMTAMSRLLILISTAQQ---QGQISDKEETQTIVSTIWASLHGVIHLYMGGFLGD 199 E+ T A L +L AQ G + I +WA+ HG+I L G + Sbjct: 149 EA---TAAANQSLAVLHEAAQHCIDTGIFRPNADPTEITEVLWAAAHGIISLERAGHIPP 205 Query: 200 ADAAH 204 A H Sbjct: 206 TTAPH 210 >C4EFD7.1 C4EFD7_STRRS Transcriptional regulator, TetR family Length = 208 Score = 108 bits (270), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 62/180 (34%), Positives = 95/180 (52%), Gaps = 1/180 (0%) Query: 32 ENLRKLVVDAAAAILQEEGPEAVTVRRVSQKMGCSTKIIYSLFVNKEGLAQQLYLEGCKL 91 + LR ++D A+ +L GPE++++RR++ + GCST +IY++F +KEGLA+ LYLEG + Sbjct: 22 DELRGRLLDVASQLLVTIGPESLSMRRIATEAGCSTTVIYTMFGSKEGLAEALYLEGFER 81 Query: 92 LAQRFEEVPPSSDPLQHLLDLGEAFWQFGQEYTSYYKLMFGGAFAEFKPDAESMQGTMTA 151 +R E VP + L+HL LG A+ + YY LMF A F P + A Sbjct: 82 FRRRLESVPARRNALEHLTALGPAYREAALAEPGYYALMFERAIPGFLPSERARTLARAA 141 Query: 152 MSRLLILISTAQQQGQISDKEETQTIVSTIWASLHGVIHLYMGGFLGDADAAHTVYKQTI 211 ++ L +I+ G I + + I +WA+ G I L G L D+ V TI Sbjct: 142 LNVLDRVIADCISAGYIIPT-QPRKIADALWAAAQGAISLERAGHLRDSRTYDAVTYATI 200 >A8L7B4.1 A8L7B4_FRASN Transcriptional regulator, TetR family Length = 206 Score = 97.1 bits (240), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 55/174 (31%), Positives = 97/174 (55%), Gaps = 2/174 (1%) Query: 24 QEARLQNTENLRKLVVDAAAAILQEEGPEAVTVRRVSQKMGCSTKIIYSLFVNKEGLAQQ 83 + +R E LR+ V+AAA +L GP+A+T+RRV+ +G ST ++Y++F K+G+A Sbjct: 9 RRSRAAAGEALRREAVEAAAELLVSAGPQALTMRRVATAIGASTTVLYTVFGGKDGVADA 68 Query: 84 LYLEGCKLLAQRFEEVPPSSDPLQHLLDLGEAFWQFGQEYTSYYKLMFGGAFAEFKPDAE 143 LY EG + L R E V ++DPL L +L A+ + S+Y +MF A ++P E Sbjct: 69 LYREGFERLRARLEAV-VAADPLVRLHELAHAYRRSALTDRSFYAVMFERAVPGYEPGPE 127 Query: 144 SMQGTMTAMSRLLILISTAQQQGQISDKEETQTIVSTIWASLHGVIHLYMGGFL 197 S++ +++ L+ + A G + ++ + + + A+ HG + L + G L Sbjct: 128 SLEVARASLAVLVDAVRDAMAAGLLG-GDDPEPVARLLHAAAHGAVSLEISGHL 180 >A7HWI0.1 A7HWI0_PARL1 Transcriptional regulator, TetR family Length = 226 Score = 91.3 bits (225), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 64/225 (28%), Positives = 102/225 (45%), Gaps = 25/225 (11%) Query: 6 ISNEDKPSPSTGRVLKTYQEARLQNTENLRKLVVDAAAAILQEEGPEAVTVRRVSQKMGC 65 +SNE P+ R + R+ ++DAA+ +L GP+A+++R+++ K+G Sbjct: 1 MSNETSPAADNRRTAQ-------------REALLDAASEMLMLGGPDAISLRKLATKVGT 47 Query: 66 STKIIYSLFVNKEGLAQQLYLEGCKLLAQRFEEVPPSSDPLQHLLDLGEAFWQFGQEYTS 125 ST +Y+ F KEGL L+ E LA VP + +PL L DL A+ F + S Sbjct: 48 STMAVYTAFGGKEGLITALFEEAFDRLAATELAVPRNPEPLLWLADLARAYRSFALKNPS 107 Query: 126 YYKLMFGGAF-----------AEFKPDAESMQGTMTAMSRLLILISTAQQQGQISDKEET 174 YY LM AE +P A S+ + LL + G + E Sbjct: 108 YYALMISATLPVPASLRHSNQAEGEPPARSIT-RHPSYQTLLDAVEACVADGSLPSDIEA 166 Query: 175 QTIVSTIWASLHGVIHLYMGGFLGDADAAHTVYKQTIVLLSRSLF 219 + + +WA++HG+ L + GF A+AA + T + R L Sbjct: 167 EILADALWAAVHGLSSLELAGFHISAEAAEKRFNVTAGAVLRGLL 211 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.132 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,197,675,372 Number of extensions: 43262657 Number of successful extensions: 114493 Number of sequences better than 1.0e-05: 201 Number of HSP's gapped: 114592 Number of HSP's successfully gapped: 201 Length of query: 224 Length of database: 3,060,696,203 Length adjustment: 131 Effective length of query: 93 Effective length of database: 1,826,543,238 Effective search space: 169868521134 Effective search space used: 169868521134 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)