BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0111.p (391 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C1DR77.1 C1DR77_AZOVD Beta-lactamase-like protein 430 e-118 A1JTL0.1 A1JTL0_YERE8 Putative uncharacterized protein 427 e-118 Q0KCD5.1 Q0KCD5_RALEH Beta-lactamase EC=3.5.2.6 426 e-117 C4TQX7.1 C4TQX7_YERKR Beta-lactamase 420 e-115 B1K6R3.1 B1K6R3_BURCC Beta-lactamase 419 e-115 >C1DR77.1 C1DR77_AZOVD Beta-lactamase-like protein Length = 396 Score = 430 bits (1106), Expect = e-118, Method: Compositional matrix adjust. Identities = 225/378 (59%), Positives = 265/378 (70%), Gaps = 1/378 (0%) Query: 14 LPERIDKVIDQTLTDKRLAGAVIKVAVDGELIYNRAAGFANRELNQPMREDALFRLASVS 73 L RI + Q L D+RL GAVI VA DGELI+ +AAGFA+RE +PM +A+FRLASVS Sbjct: 17 LGTRIHSTVQQALDDQRLVGAVILVARDGELIHQQAAGFADRESARPMTLEAVFRLASVS 76 Query: 74 KPITSTAALVLVAQGRLQLDDRVDRWLPEFQPRLKNGEHAAITIRHLMTHTAGLTYRFFQ 133 KPI STAAL LVAQGRL LD ++ WLPEFQPRL + A IT+R L++HTAGL YRFF+ Sbjct: 77 KPIVSTAALALVAQGRLDLDAGIEHWLPEFQPRLADRRSARITVRQLLSHTAGLGYRFFE 136 Query: 134 EE-GGSYEQAGVSDGMDQPGITLDENLRRIASAPLLYTPGTQWRYSIATDVLGAVIARVA 192 + G Y +AGVSDGMD GI+L+ENLRR+AS PLLY PGT W YS+ATDVLGA+IAR Sbjct: 137 ADTAGPYARAGVSDGMDASGISLEENLRRLASVPLLYEPGTAWGYSLATDVLGALIARAH 196 Query: 193 GTTLSEAIDALVTRPLGMKDTGFLATDPQRLATAYADDVPGLRPLHNPDSLAFMEGTAGF 252 GT L EA+ LVT PLGM DTGF+A DPQR+ATAY +D P L ++++ EG G Sbjct: 197 GTPLHEAVRQLVTGPLGMVDTGFVARDPQRVATAYVNDAPQPHRLAEGETVSAFEGAVGI 256 Query: 253 RLSPGRALDPAAYHSGGAGMVGSTGDFLHLLETLRKGGAPLLPEPLVREMTTNQIGDLHM 312 SP R DP A+ SGGAGM G+ D L LLE LR+G LP + EM +Q + Sbjct: 257 TYSPSRIFDPQAFPSGGAGMAGTAQDLLRLLEALRQGCGAFLPNEWIAEMARDQTDGREL 316 Query: 313 PFWPGRGFGLGITVLKDPVAADTAESPGTWRMGGTYGHSWFVDPEQRLSVAAFTNTALEG 372 P PG GFGLG +VL+DPV A + ES GTWR GG YGHSWFVD Q LSV AFTNT EG Sbjct: 317 PDAPGFGFGLGFSVLRDPVLAASPESAGTWRWGGAYGHSWFVDRAQGLSVVAFTNTLYEG 376 Query: 373 MSGPFTIDLCNAVYGRLN 390 MSG F DL +AVYG L Sbjct: 377 MSGRFVTDLRDAVYGALE 394 >A1JTL0.1 A1JTL0_YERE8 Putative uncharacterized protein Length = 390 Score = 427 bits (1099), Expect = e-118, Method: Compositional matrix adjust. Identities = 218/380 (57%), Positives = 271/380 (71%), Gaps = 1/380 (0%) Query: 8 TINLDRLPERIDKVIDQTLTDKRLAGAVIKVAVDGELIYNRAAGFANRELNQPMREDALF 67 +I+ + LP R++ IDQ L + RL GAV+ +A++GE+ + RAAG A RE +PM D LF Sbjct: 8 SIHPEHLPIRVNAAIDQALAEHRLVGAVVIIALNGEIHFCRAAGLAERETARPMTVDTLF 67 Query: 68 RLASVSKPITSTAALVLVAQGRLQLDDRVDRWLPEFQPRLKNGEHAAITIRHLMTHTAGL 127 RLAS+SKPI STAA+VLVAQG+L+LD + RWLP+FQPRL GE A IT+R L++HTAGL Sbjct: 68 RLASISKPIVSTAAMVLVAQGKLELDGDIRRWLPDFQPRLAQGELADITVRQLLSHTAGL 127 Query: 128 TYRFFQ-EEGGSYEQAGVSDGMDQPGITLDENLRRIASAPLLYTPGTQWRYSIATDVLGA 186 YRF + ++ G Y +AGVSDGMD+ ITL ENLRR+A+ PL + PGT WRYS+A DV+GA Sbjct: 128 GYRFSEADDDGPYARAGVSDGMDKSEITLHENLRRLATVPLHFAPGTSWRYSLAIDVIGA 187 Query: 187 VIARVAGTTLSEAIDALVTRPLGMKDTGFLATDPQRLATAYADDVPGLRPLHNPDSLAFM 246 VI +V G L++AI ALVT PL M DT F D RLAT Y +D+P R L + +AF Sbjct: 188 VIEQVCGQPLNQAIRALVTGPLQMNDTDFFTRDIGRLATPYVNDLPAPRLLQEGECVAFS 247 Query: 247 EGTAGFRLSPGRALDPAAYHSGGAGMVGSTGDFLHLLETLRKGGAPLLPEPLVREMTTNQ 306 G R SP RAL+ ++ SGGAGMVGS D L LLETLR+GGAPLLP LV EM +Q Sbjct: 248 PEEIGVRFSPARALNAQSFSSGGAGMVGSASDLLRLLETLRQGGAPLLPATLVDEMGRDQ 307 Query: 307 IGDLHMPFWPGRGFGLGITVLKDPVAADTAESPGTWRMGGTYGHSWFVDPEQRLSVAAFT 366 G + +P PG GFGLG +VL++P+ A + ES GTW GG YGHSWFVDP Q LSV A T Sbjct: 308 TGGIPLPDAPGIGFGLGFSVLRNPLEAASPESIGTWSWGGVYGHSWFVDPMQELSVVALT 367 Query: 367 NTALEGMSGPFTIDLCNAVY 386 NT EGMSG F DL +A+Y Sbjct: 368 NTLYEGMSGQFVNDLRDAIY 387 >Q0KCD5.1 Q0KCD5_RALEH Beta-lactamase EC=3.5.2.6 Length = 400 Score = 426 bits (1095), Expect = e-117, Method: Compositional matrix adjust. Identities = 222/372 (59%), Positives = 264/372 (70%), Gaps = 1/372 (0%) Query: 17 RIDKVIDQTLTDKRLAGAVIKVAVDGELIYNRAAGFANRELNQPMREDALFRLASVSKPI 76 RID V+ Q L +RL GAV+ V+ DGEL++ +AAG A+RE QPMR DA+FRLASVSKPI Sbjct: 23 RIDAVVRQALEQRRLVGAVVLVSRDGELVHRQAAGLADRESGQPMRMDAVFRLASVSKPI 82 Query: 77 TSTAALVLVAQGRLQLDDRVDRWLPEFQPRLKNGEHAAITIRHLMTHTAGLTYRFFQE-E 135 S AAL LVAQGRL+LD +DRWLPEF+PRL +G A IT R L++HTAGL YRFF+ E Sbjct: 83 VSVAALALVAQGRLELDQGIDRWLPEFRPRLADGRPARITARQLLSHTAGLGYRFFESGE 142 Query: 136 GGSYEQAGVSDGMDQPGITLDENLRRIASAPLLYTPGTQWRYSIATDVLGAVIARVAGTT 195 G Y +AGVSDGMD I+L ENLRRIAS PLLY PGT W YS+ATDVLGA+I RV GT Sbjct: 143 DGPYARAGVSDGMDDATISLAENLRRIASVPLLYEPGTAWGYSLATDVLGALIERVHGTP 202 Query: 196 LSEAIDALVTRPLGMKDTGFLATDPQRLATAYADDVPGLRPLHNPDSLAFMEGTAGFRLS 255 L A+ LVT PLGM DTGF+A D R+ T Y +D P L +++ +EGT G S Sbjct: 203 LDTAVRQLVTGPLGMADTGFVAHDVHRVPTPYVNDSPHPHRLREGETVPVLEGTVGIPYS 262 Query: 256 PGRALDPAAYHSGGAGMVGSTGDFLHLLETLRKGGAPLLPEPLVREMTTNQIGDLHMPFW 315 P R + A+ SGGAGM G+ DFL LLE+LR+GG LLP LV +M +Q G L +P Sbjct: 263 PARIFNARAFPSGGAGMAGTAQDFLCLLESLRQGGGALLPSALVEDMALDQTGGLDLPDA 322 Query: 316 PGRGFGLGITVLKDPVAADTAESPGTWRMGGTYGHSWFVDPEQRLSVAAFTNTALEGMSG 375 PG GFGLG +VL+DP A + E+ GTWR GG YGH+WFVD Q LSV AFTNT EGMSG Sbjct: 323 PGTGFGLGFSVLRDPRRAGSPEAAGTWRWGGAYGHAWFVDRSQGLSVVAFTNTLYEGMSG 382 Query: 376 PFTIDLCNAVYG 387 F DL +AVYG Sbjct: 383 RFVTDLRDAVYG 394 >C4TQX7.1 C4TQX7_YERKR Beta-lactamase Length = 393 Score = 420 bits (1080), Expect = e-115, Method: Compositional matrix adjust. Identities = 217/375 (57%), Positives = 263/375 (70%), Gaps = 1/375 (0%) Query: 14 LPERIDKVIDQTLTDKRLAGAVIKVAVDGELIYNRAAGFANRELNQPMREDALFRLASVS 73 L RI+ VIDQ L+++RL GAV+ VA++GE + RAAG+A+RE PM + LFRLAS+S Sbjct: 14 LASRINAVIDQALSEQRLVGAVVMVALNGETHFCRAAGWADRETEHPMAANTLFRLASIS 73 Query: 74 KPITSTAALVLVAQGRLQLDDRVDRWLPEFQPRLKNGEHAAITIRHLMTHTAGLTYRFFQ 133 KPI STAA+VLVAQG+L LD + WLP+FQPRL +GE IT+R L++HTAGL YRF + Sbjct: 74 KPIVSTAAMVLVAQGKLDLDGDIRHWLPDFQPRLADGELPQITVRQLLSHTAGLGYRFVE 133 Query: 134 -EEGGSYEQAGVSDGMDQPGITLDENLRRIASAPLLYTPGTQWRYSIATDVLGAVIARVA 192 +E G Y +AG+SDGMDQ ITL ENLRR+A PL Y PGT W YS+A DVLGAVI +V Sbjct: 134 ADENGPYARAGISDGMDQSAITLSENLRRLAEVPLYYAPGTSWAYSLAIDVLGAVIEQVY 193 Query: 193 GTTLSEAIDALVTRPLGMKDTGFLATDPQRLATAYADDVPGLRPLHNPDSLAFMEGTAGF 252 G L +A+ ALVT PL M DT F D RL+T Y +D+P PL + +A T G Sbjct: 194 GQPLDKAVRALVTGPLQMDDTEFFTHDISRLSTPYVNDIPAPHPLQEGEIVAPFPDTVGI 253 Query: 253 RLSPGRALDPAAYHSGGAGMVGSTGDFLHLLETLRKGGAPLLPEPLVREMTTNQIGDLHM 312 SP RAL+ A+ SGGAGMVGS D L LLETLR+GG+PLLP LV EM +Q + + Sbjct: 254 EFSPARALNRHAFPSGGAGMVGSASDLLRLLETLRQGGSPLLPAALVDEMGQDQTRGMTL 313 Query: 313 PFWPGRGFGLGITVLKDPVAADTAESPGTWRMGGTYGHSWFVDPEQRLSVAAFTNTALEG 372 P PG GFGLG +VL+DP AAD+ ES GTW GG YGHSWFVD Q +SV A TNT EG Sbjct: 314 PDSPGLGFGLGFSVLRDPDAADSPESVGTWSWGGAYGHSWFVDKIQGISVVALTNTLYEG 373 Query: 373 MSGPFTIDLCNAVYG 387 MSG F DL +AVYG Sbjct: 374 MSGQFVNDLRDAVYG 388 >B1K6R3.1 B1K6R3_BURCC Beta-lactamase Length = 393 Score = 419 bits (1077), Expect = e-115, Method: Compositional matrix adjust. Identities = 216/375 (57%), Positives = 265/375 (70%), Gaps = 1/375 (0%) Query: 14 LPERIDKVIDQTLTDKRLAGAVIKVAVDGELIYNRAAGFANRELNQPMREDALFRLASVS 73 L RID V+ + L +RL GAV+ VA DGEL+Y RAAGFA+RE PMRED LFRLASV+ Sbjct: 17 LAARIDAVLSRQLDTQRLVGAVVLVARDGELVYRRAAGFADRESRTPMREDTLFRLASVT 76 Query: 74 KPITSTAALVLVAQGRLQLDDRVDRWLPEFQPRLKNGEHAAITIRHLMTHTAGLTYRFFQ 133 KPI S AA+ LVAQ +L LD+ + RWLP+F+P L +G IT+R L+ HTAGL YRF + Sbjct: 77 KPIVSAAAMALVAQRKLSLDEDIARWLPDFRPALPDGRVPTITVRQLLVHTAGLDYRFNE 136 Query: 134 EEG-GSYEQAGVSDGMDQPGITLDENLRRIASAPLLYTPGTQWRYSIATDVLGAVIARVA 192 + G Y +AGVSDG+D ITL ENLRRIAS PLL+ PGT W YS++ DV+GA+I V Sbjct: 137 TDANGPYARAGVSDGLDGASITLAENLRRIASVPLLFAPGTSWNYSLSIDVIGALIEAVC 196 Query: 193 GTTLSEAIDALVTRPLGMKDTGFLATDPQRLATAYADDVPGLRPLHNPDSLAFMEGTAGF 252 G L++AIDALV RPLG +DTGF+A DP RLAT Y +D P L +++ EG G Sbjct: 197 GVPLADAIDALVLRPLGARDTGFVARDPARLATPYVNDTPQPHRLAENETVPIDEGFVGV 256 Query: 253 RLSPGRALDPAAYHSGGAGMVGSTGDFLHLLETLRKGGAPLLPEPLVREMTTNQIGDLHM 312 SP RALD A+ SGGAGMVGS GD L +L+TLR GG +LP LV EM Q GDL + Sbjct: 257 TYSPSRALDAHAFPSGGAGMVGSAGDVLTVLDTLRAGGGTILPAELVDEMGRVQTGDLEL 316 Query: 313 PFWPGRGFGLGITVLKDPVAADTAESPGTWRMGGTYGHSWFVDPEQRLSVAAFTNTALEG 372 P PG GFG+G +VL+DP AA + ES GTWR GG YGHSWFVD + L+V + TNT EG Sbjct: 317 PDLPGAGFGIGFSVLRDPQAAASPESVGTWRWGGVYGHSWFVDRARGLTVVSLTNTLYEG 376 Query: 373 MSGPFTIDLCNAVYG 387 M+G +T+DL +AVYG Sbjct: 377 MNGQYTLDLRDAVYG 391 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.137 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,484,036,250 Number of extensions: 111154624 Number of successful extensions: 256838 Number of sequences better than 1.0e-05: 3097 Number of HSP's gapped: 252837 Number of HSP's successfully gapped: 3109 Length of query: 391 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 253 Effective length of database: 1,760,596,133 Effective search space: 445430821649 Effective search space used: 445430821649 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 132 (55.5 bits)