BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0074.p (322 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A7FVA7.1 A7FVA7_CLOB1 Glucose-1-phosphate thymidylyltransferase ... 208 4e-52 A5I3H6.1 A5I3H6_CLOBH Glucose-1-phosphate thymidylyltransferase ... 208 4e-52 B1IFP3.1 B1IFP3_CLOBK Glucose-1-phosphate thymidylyltransferase ... 208 5e-52 A7GF11.1 A7GF11_CLOBL Glucose-1-phosphate thymidylyltransferase ... 208 5e-52 B1QBT5.1 B1QBT5_CLOBO Glucose-1-phosphate thymidylyltransferase ... 208 5e-52 >A7FVA7.1 A7FVA7_CLOB1 Glucose-1-phosphate thymidylyltransferase EC=2.7.7.24 Length = 353 Score = 208 bits (530), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 118/329 (35%), Positives = 184/329 (55%), Gaps = 21/329 (6%) Query: 1 MLPVNGEYILVSIINKLVAAGITEIGIVVNHTQGEIRRTIGDGERWNASLTFLMQEEPMG 60 +LP+ + IL II K+V AGI +IGI+V T+ E+++ +G+G+RW +++L Q P+G Sbjct: 25 LLPLANKPILFYIIEKIVKAGIYDIGIIVGDTREEVKKMVGNGDRWGVKISYLYQPMPLG 84 Query: 61 LADAVKSAKSFMADSPFVLMLGDNLYEGDIAPLIRSLETDNAAASILLQQVKDPGQFGVA 120 LA AVK+A F+ + F+++LGDN++ ++ LI S ++NA +++LL +V++P Q+GVA Sbjct: 85 LAHAVKTASEFLMEDDFLMVLGDNVFNMELNKLIDSFYSNNANSALLLHKVENPSQYGVA 144 Query: 121 AVHAGQIIGLEEKPKYPKSDLAIVGVYALTAAIWPAMDRLTPSPRGEYEMTDAIQLLITE 180 V II L EKPK SDL I GVY +I+ A+D + PS RGE E+TDAIQ + Sbjct: 145 VVEDTLIIKLVEKPKEFVSDLIITGVYIFDKSIFMAIDNIKPSQRGELEITDAIQKQLET 204 Query: 181 GGHVVYSIAAEPFFDIGTHDRWLEANRYKMGQDPQNF---------------VKPSGMHS 225 GG V Y + + D G LEANR + + F + + + Sbjct: 205 GGRVTYELIQGWWKDTGQLQDILEANRLMLDEIDCEFKTLPQSNSVFMGKIQIGKNVIIE 264 Query: 226 SVQWIPPVRIDPTATVMNSVVGPYVYIGPNSVVEDCILSNSILTDQVTLSHVHAE--GSV 283 + I PV I T+ NS +GPY I V DC + N I+ + + +H GS+ Sbjct: 265 NSTIIGPVAIADDTTITNSCIGPYTSIDKAVTVNDCEIDNCIILENAKIDGIHKRISGSL 324 Query: 284 FGSYVHLAEQEIQEQPARH--ILGDRASV 310 G V + +E+ ++P H +LGD + + Sbjct: 325 IGRKVQI--KELHKRPFSHTFLLGDDSEI 351 >A5I3H6.1 A5I3H6_CLOBH Glucose-1-phosphate thymidylyltransferase EC=2.7.7.24 Length = 353 Score = 208 bits (530), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 118/329 (35%), Positives = 184/329 (55%), Gaps = 21/329 (6%) Query: 1 MLPVNGEYILVSIINKLVAAGITEIGIVVNHTQGEIRRTIGDGERWNASLTFLMQEEPMG 60 +LP+ + IL II K+V AGI +IGI+V T+ E+++ +G+G+RW +++L Q P+G Sbjct: 25 LLPLANKPILFYIIEKIVKAGIYDIGIIVGDTREEVKKMVGNGDRWGVKISYLYQPMPLG 84 Query: 61 LADAVKSAKSFMADSPFVLMLGDNLYEGDIAPLIRSLETDNAAASILLQQVKDPGQFGVA 120 LA AVK+A F+ + F+++LGDN++ ++ LI S ++NA +++LL +V++P Q+GVA Sbjct: 85 LAHAVKTASEFLMEDDFLMVLGDNVFNMELNKLIDSFYSNNANSALLLHKVENPSQYGVA 144 Query: 121 AVHAGQIIGLEEKPKYPKSDLAIVGVYALTAAIWPAMDRLTPSPRGEYEMTDAIQLLITE 180 V II L EKPK SDL I GVY +I+ A+D + PS RGE E+TDAIQ + Sbjct: 145 VVEDTLIIKLVEKPKEFVSDLIITGVYIFDKSIFMAIDNIKPSQRGELEITDAIQKQLET 204 Query: 181 GGHVVYSIAAEPFFDIGTHDRWLEANRYKMGQDPQNF---------------VKPSGMHS 225 GG V Y + + D G LEANR + + F + + + Sbjct: 205 GGRVTYELIQGWWKDTGQLQDILEANRLMLDEIDCEFKTLPQSNSVFMGKIQIGKNVIIE 264 Query: 226 SVQWIPPVRIDPTATVMNSVVGPYVYIGPNSVVEDCILSNSILTDQVTLSHVHAE--GSV 283 + I PV I T+ NS +GPY I V DC + N I+ + + +H GS+ Sbjct: 265 NSTIIGPVAIADDTTITNSCIGPYTSIDKAVTVNDCEIDNCIILENAKIDGIHKRISGSL 324 Query: 284 FGSYVHLAEQEIQEQPARH--ILGDRASV 310 G V + +E+ ++P H +LGD + + Sbjct: 325 IGRKVQI--KELHKRPFSHTFLLGDDSEI 351 >B1IFP3.1 B1IFP3_CLOBK Glucose-1-phosphate thymidylyltransferase EC=2.7.7.24 Length = 353 Score = 208 bits (530), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 118/329 (35%), Positives = 184/329 (55%), Gaps = 21/329 (6%) Query: 1 MLPVNGEYILVSIINKLVAAGITEIGIVVNHTQGEIRRTIGDGERWNASLTFLMQEEPMG 60 +LP+ + IL II K+V AGI +IGI+V T+ E+++ +G+G+RW +++L Q P+G Sbjct: 25 LLPLANKPILFYIIEKIVKAGIYDIGIIVGDTREEVKKMVGNGDRWGVKISYLYQPAPLG 84 Query: 61 LADAVKSAKSFMADSPFVLMLGDNLYEGDIAPLIRSLETDNAAASILLQQVKDPGQFGVA 120 LA AVK+A F+ + F+++LGDN++ ++ LI S ++NA +++LL +V++P Q+GVA Sbjct: 85 LAHAVKTASEFLMEDDFLMVLGDNVFNMELNKLIDSFYSNNANSALLLHKVENPSQYGVA 144 Query: 121 AVHAGQIIGLEEKPKYPKSDLAIVGVYALTAAIWPAMDRLTPSPRGEYEMTDAIQLLITE 180 V II L EKPK SDL I GVY +I+ A+D + PS RGE E+TDAIQ + Sbjct: 145 VVEDTLIIKLVEKPKEFVSDLIITGVYIFDKSIFMAIDNIKPSQRGELEITDAIQKQLET 204 Query: 181 GGHVVYSIAAEPFFDIGTHDRWLEANRYKMGQDPQNF---------------VKPSGMHS 225 GG V Y + + D G LEANR + + F + + + Sbjct: 205 GGRVTYELIQGWWKDTGQLQDILEANRLMLDEIDCEFKTLPQSNSVFMGKIQIGRNVIIE 264 Query: 226 SVQWIPPVRIDPTATVMNSVVGPYVYIGPNSVVEDCILSNSILTDQVTLSHVHAE--GSV 283 + I PV I T+ NS +GPY I V DC + N I+ + + +H GS+ Sbjct: 265 NSTIIGPVAIADDTTITNSCIGPYTSIDKAVTVNDCEIDNCIILENAKIDGIHKRISGSL 324 Query: 284 FGSYVHLAEQEIQEQPARH--ILGDRASV 310 G V + +E+ ++P H +LGD + + Sbjct: 325 IGRKVQI--KELHKRPFSHTFLLGDDSEI 351 >A7GF11.1 A7GF11_CLOBL Glucose-1-phosphate thymidylyltransferase EC=2.7.7.24 Length = 353 Score = 208 bits (530), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 118/329 (35%), Positives = 184/329 (55%), Gaps = 21/329 (6%) Query: 1 MLPVNGEYILVSIINKLVAAGITEIGIVVNHTQGEIRRTIGDGERWNASLTFLMQEEPMG 60 +LP+ + IL II K+V AGI +IGI+V T+ E+++ +G+G+RW +++L Q P+G Sbjct: 25 LLPLANKPILFYIIEKIVKAGIYDIGIIVGDTREEVKKMVGNGDRWGVKISYLYQPAPLG 84 Query: 61 LADAVKSAKSFMADSPFVLMLGDNLYEGDIAPLIRSLETDNAAASILLQQVKDPGQFGVA 120 LA AVK+A F+ + F+++LGDN++ ++ LI S ++NA +++LL +V++P Q+GVA Sbjct: 85 LAHAVKTASEFLMEDDFLMVLGDNVFNMELNKLIDSFYSNNANSALLLHKVENPSQYGVA 144 Query: 121 AVHAGQIIGLEEKPKYPKSDLAIVGVYALTAAIWPAMDRLTPSPRGEYEMTDAIQLLITE 180 V II L EKPK SDL I GVY +I+ A+D + PS RGE E+TDAIQ + Sbjct: 145 VVEDTLIIKLVEKPKEFVSDLIITGVYIFDKSIFMAIDNIKPSQRGELEITDAIQKQLET 204 Query: 181 GGHVVYSIAAEPFFDIGTHDRWLEANRYKMGQDPQNF---------------VKPSGMHS 225 GG V Y + + D G LEANR + + F + + + Sbjct: 205 GGRVTYELIQGWWKDTGQLQDILEANRLMLDEIDCEFKTLPQSNSVFMGKIQIGRNVIIE 264 Query: 226 SVQWIPPVRIDPTATVMNSVVGPYVYIGPNSVVEDCILSNSILTDQVTLSHVHAE--GSV 283 + I PV I T+ NS +GPY I V DC + N I+ + + +H GS+ Sbjct: 265 NSTIIGPVAIADDTTITNSCIGPYTSIDKAVTVNDCEIDNCIILENAKIDGIHKRISGSL 324 Query: 284 FGSYVHLAEQEIQEQPARH--ILGDRASV 310 G V + +E+ ++P H +LGD + + Sbjct: 325 IGRKVQI--KELHKRPFSHTFLLGDDSEI 351 >B1QBT5.1 B1QBT5_CLOBO Glucose-1-phosphate thymidylyltransferase EC=2.7.7.24 Length = 353 Score = 208 bits (530), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 121/329 (36%), Positives = 183/329 (55%), Gaps = 21/329 (6%) Query: 1 MLPVNGEYILVSIINKLVAAGITEIGIVVNHTQGEIRRTIGDGERWNASLTFLMQEEPMG 60 +LP+ + IL II K+V AGI +IGI+V T+ E+++ +G+G+RW +++L Q P+G Sbjct: 25 LLPLANKPILFYIIEKIVKAGIYDIGIIVGDTREEVKKMVGNGDRWGVKISYLYQPMPLG 84 Query: 61 LADAVKSAKSFMADSPFVLMLGDNLYEGDIAPLIRSLETDNAAASILLQQVKDPGQFGVA 120 LA AVK+A F+ + F+++LGDN++ ++ LI S ++NA +++LL +V++P Q+GVA Sbjct: 85 LAHAVKTASEFLMEDDFLMVLGDNVFNMELNKLIDSFYSNNANSALLLHKVENPSQYGVA 144 Query: 121 AVHAGQIIGLEEKPKYPKSDLAIVGVYALTAAIWPAMDRLTPSPRGEYEMTDAIQLLITE 180 V II L EKPK SDL I GVY +I+ A+D + PS RGE E+TDAIQ + Sbjct: 145 VVEDTLIIKLVEKPKEFVSDLIITGVYIFDKSIFMAIDNIKPSQRGELEITDAIQKQLET 204 Query: 181 GGHVVYSIAAEPFFDIGTHDRWLEANRYKMGQDPQNFV----KPSGMHSSVQ-------- 228 GG V Y + + D G LEANR + + F S VQ Sbjct: 205 GGRVTYELIQGWWKDTGQLQDILEANRLMLDEIDCEFKTLPQSNSVFMGKVQIGRNVIIE 264 Query: 229 ---WIPPVRIDPTATVMNSVVGPYVYIGPNSVVEDCILSNSILTDQVTLSHVHAE--GSV 283 I PV I T+ NS +GPY I V DC + N I+ + + +H GS+ Sbjct: 265 NSTIIGPVAIADDTTITNSCIGPYTSIDKAVTVNDCEIDNCIILENAKIDGIHKRISGSL 324 Query: 284 FGSYVHLAEQEIQEQPARH--ILGDRASV 310 G V + +E+ ++P H +LGD + + Sbjct: 325 IGRKVQI--KELHKRPFSHTFLLGDDSEI 351 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.134 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,922,099,898 Number of extensions: 79533527 Number of successful extensions: 184145 Number of sequences better than 1.0e-05: 3940 Number of HSP's gapped: 179601 Number of HSP's successfully gapped: 3940 Length of query: 322 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 186 Effective length of database: 1,779,438,163 Effective search space: 330975498318 Effective search space used: 330975498318 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)