BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0067.p (601 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C3B3A1.1 C3B3A1_BACMY Response regulator receiver 506 e-141 C3AL44.1 C3AL44_BACMY Response regulator receiver 506 e-141 C3BJY8.1 C3BJY8_9BACI Response regulator receiver 461 e-128 B3KFB6.1 B3KFB6_9BACI Response regulator receiver 429 e-118 C0Z7M8.1 C0Z7M8_BREBN Two-component hybrid sensor and regulator ... 422 e-116 >C3B3A1.1 C3B3A1_BACMY Response regulator receiver Length = 578 Score = 506 bits (1303), Expect = e-141, Method: Compositional matrix adjust. Identities = 265/582 (45%), Positives = 381/582 (65%), Gaps = 7/582 (1%) Query: 15 VLLLRLLWSMAVIILMYQDKPDFXXXXXXXXXXXXXXXXSWVGRNFTTRYXXXXXXXXXX 74 ++L+R+ W +A++ L YQD P+F + + + Y Sbjct: 1 MILIRITWIVAIVTLTYQDNPNFPLEIVFISTFLSYVIPVILYKLQSELYVVTEIILVGG 60 Query: 75 XXXXXXXXXXXTRLFLPAVLMLAFHTRGKAHFYXXXXXXXXXXXXAGPTIQAGLSHPLIW 134 + PA+L LAF RGK +FY G + G + Sbjct: 61 LSLYFAYTYHLAQFLSPAILTLAFFCRGKVNFYALPAMIIICVL--GVFLNFGFDRNKLL 118 Query: 135 LSLSDGLFVYAAGYGLQVGAKSINGIRQKLALVNEQYAILEQYSSQIERMTLLEERYRMA 194 LS+ D LF+Y G+ LQ S++ I++KL L+ ++ AILEQYSSQ+ER+TLLEER RMA Sbjct: 119 LSIFDVLFIYGVGHLLQRVVYSMDAIKKKLKLIKDKNAILEQYSSQVERITLLEERDRMA 178 Query: 195 REVHDTIGHSYTSIILGLETLKPHVASQEGEHKLQGVLELARKGLDDVRLQVHQMDPLEE 254 RE+HDTIG+ +TS+IL +ETL+PH+A++EGE KLQ +L+++R LD++R QVH+MDP EE Sbjct: 179 RELHDTIGYKFTSVILSMETLRPHLATKEGEGKLQEILDISRSALDNIRRQVHEMDPQEE 238 Query: 255 PVTLDRALMQIAGQFESNTGVTLSFRTMGEPYAVIKQAKHTLSRSLQEALTNASRHGQAS 314 LD +L+ + +F+SNT V + FRT+GE Y + K+ K T R LQEA+TNA+RHG A Sbjct: 239 S-NLDVSLLNLIEEFKSNTNVHVVFRTVGEYYPMAKKLKRTFCRCLQEAMTNATRHGGAE 297 Query: 315 AIRVVLQYDPAQLMLQIQDNGKGTAQLRYGFGLTGMKERLAALQGKLYIDSQENDGTLVT 374 I+V+LQY +MLQIQD+G G ++ GFGL+GM+ERL+ G L IDS ++ GT+VT Sbjct: 298 TIQVLLQYHKNYVMLQIQDDGIGMEVMQEGFGLSGMRERLSEYHGNLSIDSTKDTGTIVT 357 Query: 375 CIIPNQTQE---GERRIDILLADDQPLVRESLRLLLGEEKDFRLRTAASGKQALEQCAAE 431 C+IP +E + +I IL+ DDQP++ +SL LL ++ FR+ A SG QAL+QC Sbjct: 358 CLIPTLHKEESFAQDKIHILIVDDQPIISDSLEFLL-DKYGFRVSVANSGAQALKQCEER 416 Query: 432 QPDIVLMDIHMPEMDGLEATRQLKEKWPEVRVIIITTFEEITYAAEALRLGAEGYLLKTL 491 QP++VLMDI MP+M+G+ +++K +WP+ ++I++TTFEE + +EA+ GAEGY+LK++ Sbjct: 417 QPNVVLMDIQMPKMNGITTMKKIKNRWPDTKIIMVTTFEETSSVSEAIEAGAEGYVLKSV 476 Query: 492 HPKELAATIRLIYGGGTMISQEVAQQLFQDQQLEAPLNPYDLTERELEVLQELTEGLRNK 551 P+EL A IRL++ GGTM+SQ+VA +LF++ PY+LT RE++VL L EGLR K Sbjct: 477 QPEELVAAIRLVHLGGTMLSQDVATRLFKEYSPMPKKPPYELTPREMDVLGCLKEGLRYK 536 Query: 552 QIAQKLHLSEGTVRNYISAIYLKLQVGDRDEAVEKSKKEQLV 593 +IA KL LSEGTVRNY S+IY+KLQV R EAV+K+ E + Sbjct: 537 EIAAKLFLSEGTVRNYASSIYMKLQVSGRGEAVKKALDEAFL 578 >C3AL44.1 C3AL44_BACMY Response regulator receiver Length = 578 Score = 506 bits (1303), Expect = e-141, Method: Compositional matrix adjust. Identities = 265/582 (45%), Positives = 381/582 (65%), Gaps = 7/582 (1%) Query: 15 VLLLRLLWSMAVIILMYQDKPDFXXXXXXXXXXXXXXXXSWVGRNFTTRYXXXXXXXXXX 74 ++L+R+ W +A++ L YQD P+F + + + Y Sbjct: 1 MILIRITWIVAIVTLTYQDNPNFPLEIVFISTFLSYVIPVILYKLQSELYVVTEIILVGG 60 Query: 75 XXXXXXXXXXXTRLFLPAVLMLAFHTRGKAHFYXXXXXXXXXXXXAGPTIQAGLSHPLIW 134 + PA+L LAF RGK +FY G + G + Sbjct: 61 LSLYFAYTYHLAQFLSPAILTLAFFCRGKVNFYALPAMIIICVL--GVFLNFGFDRNKLL 118 Query: 135 LSLSDGLFVYAAGYGLQVGAKSINGIRQKLALVNEQYAILEQYSSQIERMTLLEERYRMA 194 LS+ D LF+Y G+ LQ S++ I++KL L+ ++ AILEQYSSQ+ER+TLLEER RMA Sbjct: 119 LSIFDVLFIYGVGHLLQRVVYSMDAIKKKLKLIKDKNAILEQYSSQVERITLLEERDRMA 178 Query: 195 REVHDTIGHSYTSIILGLETLKPHVASQEGEHKLQGVLELARKGLDDVRLQVHQMDPLEE 254 RE+HDTIG+ +TS+IL +ETL+PH+A++EGE KLQ +L+++R LD++R QVH+MDP EE Sbjct: 179 RELHDTIGYKFTSVILSMETLRPHLATKEGEGKLQEILDISRSALDNIRRQVHEMDPQEE 238 Query: 255 PVTLDRALMQIAGQFESNTGVTLSFRTMGEPYAVIKQAKHTLSRSLQEALTNASRHGQAS 314 LD +L+ + +F+SNT V + FRT+GE Y + K+ K T R LQEA+TNA+RHG A Sbjct: 239 S-NLDVSLLNLIEEFKSNTNVHVVFRTVGEYYPMAKKLKRTFCRCLQEAMTNATRHGGAE 297 Query: 315 AIRVVLQYDPAQLMLQIQDNGKGTAQLRYGFGLTGMKERLAALQGKLYIDSQENDGTLVT 374 I+V+LQY +MLQIQD+G G ++ GFGL+GM+ERL+ G L IDS ++ GT+VT Sbjct: 298 TIQVLLQYHKNYVMLQIQDDGIGMEVMQEGFGLSGMRERLSEYHGNLSIDSTKDTGTIVT 357 Query: 375 CIIPNQTQE---GERRIDILLADDQPLVRESLRLLLGEEKDFRLRTAASGKQALEQCAAE 431 C+IP +E + +I IL+ DDQP++ +SL LL ++ FR+ A SG QAL+QC Sbjct: 358 CLIPTLHKEESFAQDKIHILIVDDQPIISDSLEFLL-DKYGFRVSVANSGAQALKQCEER 416 Query: 432 QPDIVLMDIHMPEMDGLEATRQLKEKWPEVRVIIITTFEEITYAAEALRLGAEGYLLKTL 491 QP++VLMDI MP+M+G+ +++K +WP+ ++I++TTFEE + +EA+ GAEGY+LK++ Sbjct: 417 QPNVVLMDIQMPKMNGITTMKKIKNRWPDTKIIMVTTFEETSSVSEAIEAGAEGYVLKSV 476 Query: 492 HPKELAATIRLIYGGGTMISQEVAQQLFQDQQLEAPLNPYDLTERELEVLQELTEGLRNK 551 P+EL A IRL++ GGTM+SQ+VA +LF++ PY+LT RE++VL L EGLR K Sbjct: 477 QPEELVAAIRLVHLGGTMLSQDVATRLFKEYSPMPKKPPYELTPREMDVLGCLKEGLRYK 536 Query: 552 QIAQKLHLSEGTVRNYISAIYLKLQVGDRDEAVEKSKKEQLV 593 +IA KL LSEGTVRNY S+IY+KLQV R EAV+K+ E + Sbjct: 537 EIAAKLFLSEGTVRNYASSIYMKLQVSGRGEAVKKALDEAFL 578 >C3BJY8.1 C3BJY8_9BACI Response regulator receiver Length = 438 Score = 461 bits (1187), Expect = e-128, Method: Compositional matrix adjust. Identities = 226/425 (53%), Positives = 317/425 (74%), Gaps = 5/425 (1%) Query: 172 AILEQYSSQIERMTLLEERYRMAREVHDTIGHSYTSIILGLETLKPHVASQEGEHKLQGV 231 AILEQYSSQ+ER+TLLEER RMARE+HDTIG+ +TS+IL +ETL+ H+A++EGE KLQ + Sbjct: 16 AILEQYSSQVERITLLEERDRMARELHDTIGYKFTSVILSMETLRSHLATKEGEGKLQEI 75 Query: 232 LELARKGLDDVRLQVHQMDPLEEPVTLDRALMQIAGQFESNTGVTLSFRTMGEPYAVIKQ 291 L+++R LD++R QVH+MDP EE LD +L+ + +F+SNT V + FRT+GE Y + K+ Sbjct: 76 LDISRSALDNIRRQVHEMDPQEES-NLDVSLLNLIEEFKSNTNVHVVFRTVGEYYPMAKK 134 Query: 292 AKHTLSRSLQEALTNASRHGQASAIRVVLQYDPAQLMLQIQDNGKGTAQLRYGFGLTGMK 351 K T R LQEA+TNA+RHG A I+V+LQY +MLQIQD+G G ++ GFGL+GM+ Sbjct: 135 LKRTFCRCLQEAMTNATRHGGAETIQVLLQYHKNYVMLQIQDDGIGMEVMQEGFGLSGMR 194 Query: 352 ERLAALQGKLYIDSQENDGTLVTCIIPNQTQE---GERRIDILLADDQPLVRESLRLLLG 408 ERL+ G L IDS ++ GT+VTC+IP +E + +I IL+ DDQP++ +SL LLL Sbjct: 195 ERLSEYHGNLSIDSTKDTGTIVTCLIPTLHKEESFAQDKIHILVVDDQPIISDSLELLL- 253 Query: 409 EEKDFRLRTAASGKQALEQCAAEQPDIVLMDIHMPEMDGLEATRQLKEKWPEVRVIIITT 468 ++ FR+ A SG QAL+QC QP++V+MDI MP+M+G+ +++K +WP+ ++I++TT Sbjct: 254 DKYGFRVSVANSGAQALKQCEERQPNVVIMDIQMPKMNGITTMKKIKNRWPDTKIIMVTT 313 Query: 469 FEEITYAAEALRLGAEGYLLKTLHPKELAATIRLIYGGGTMISQEVAQQLFQDQQLEAPL 528 FEE + +EA+ GAEGY+LK++ P+EL A IRL++ GGTM+SQ+VA +LF++ Sbjct: 314 FEETSSVSEAIEAGAEGYVLKSVQPEELVAAIRLVHLGGTMLSQDVATRLFKEYSSMPKK 373 Query: 529 NPYDLTERELEVLQELTEGLRNKQIAQKLHLSEGTVRNYISAIYLKLQVGDRDEAVEKSK 588 PY+LT RE++VL L EGLR K+IA KL LSEGTVRNY S+IY+KLQV R EAV+K+ Sbjct: 374 PPYELTPREMDVLGCLKEGLRYKEIAAKLFLSEGTVRNYASSIYMKLQVSGRGEAVKKAL 433 Query: 589 KEQLV 593 E + Sbjct: 434 DEAFL 438 >B3KFB6.1 B3KFB6_9BACI Response regulator receiver Length = 601 Score = 429 bits (1102), Expect = e-118, Method: Compositional matrix adjust. Identities = 219/466 (46%), Positives = 321/466 (68%), Gaps = 22/466 (4%) Query: 149 GLQVGAKSINGIRQKLALVN--------EQYAILEQYSSQIERMTLLEERYRMAREVHDT 200 + +G I G L ++N EQ A+LEQY SQIER+TL EER R+++E+HDT Sbjct: 138 AVHIGLAYIFGFSFHLLVLNHRQGETIREQNAVLEQYLSQIERITLAEERSRLSKELHDT 197 Query: 201 IGHSYTSIILGLETLKPHVASQEGEHKLQGVLELARKGLDDVRLQVHQMDPLEEPVTLDR 260 +GH+YTS+I+GLETL+P +A+ G L +L LAR+ +++VR VHQ++ E + L + Sbjct: 198 VGHAYTSLIMGLETLRPQMATDTGTESLDSLLNLARQNMEEVRGYVHQIESPHETLPLLQ 257 Query: 261 ALMQIAGQFESNTGVTLSFRTMGEPYAVIKQAKHTLSRSLQEALTNASRHGQASAIRVVL 320 +L ++A +F+ + V ++F GE Y V+KQAK L R LQE+LTNA RHG ++ I+V + Sbjct: 258 SLRKLAEEFQEHAKVPVTFHAYGEEYPVMKQAKTALYRCLQESLTNAVRHGHSTEIKVSV 317 Query: 321 QYDPAQLMLQIQDNGKGTAQLRYGFGLTGMKERLAALQGKLYIDSQENDGTLVTCIIPNQ 380 ++P Q L+IQDNG+G R GFGL+ MKER LQG + + ++ +GTLVTC +P Q Sbjct: 318 HFEPQQTRLEIQDNGRGMEHGREGFGLSAMKERAMILQGHVAVYTERGEGTLVTCTLPRQ 377 Query: 381 TQEGERRIDILLADDQPLVRESLRLLLGEEKDFRLR-TAASGKQALEQCAAEQPDIVLMD 439 T+ + I +L+ DD P++RESLR LL E++DF++ TA G+QA+E C +P +VLMD Sbjct: 378 TELKDEVIRLLVVDDHPVIRESLRTLLEEQQDFQVVGTAEDGEQAIELCRQVRPQLVLMD 437 Query: 440 IHMPEMDGLEATRQLKEKWPEVRVIIITTFEEITYAAEALRLGAEGYLLKTLHPKELAAT 499 + MP +DG+ A+R +KE WP +R++I+TTFE+ A EA+R G +GYLLK++ P ELA T Sbjct: 438 VEMPNLDGISASRTIKESWPHIRILILTTFEDTKQALEAMRSGVDGYLLKSMQPLELAET 497 Query: 500 IRLIYGGGTMISQEVAQQLFQDQQLEA-----------PLNPYDLTERELEVLQELTEGL 548 IR ++ GGT+I Q ++ +LF QLEA + YDLT RELE+LQ ++EGL Sbjct: 498 IRTVHRGGTLIDQGMSHKLF--AQLEADNSRDDPSSIKASSAYDLTPRELEILQFVSEGL 555 Query: 549 RNKQIAQKLHLSEGTVRNYISAIYLKLQVGDRDEAVEKSKKEQLVQ 594 R K IA KL+LS+GTVRNY S++Y+KL V +R+EAV+K+++ L++ Sbjct: 556 RYKSIASKLYLSDGTVRNYASSVYMKLGVRNREEAVQKAREAGLLE 601 >C0Z7M8.1 C0Z7M8_BREBN Two-component hybrid sensor and regulator EC=2.7.3.- Length = 602 Score = 422 bits (1084), Expect = e-116, Method: Compositional matrix adjust. Identities = 219/465 (47%), Positives = 314/465 (67%), Gaps = 22/465 (4%) Query: 151 QVGAKSINGIRQKLALVN--------EQYAILEQYSSQIERMTLLEERYRMAREVHDTIG 202 QVG + G L +VN +Q ++LEQY +QIER+TLLEER R+++++HDT+G Sbjct: 138 QVGLAYVMGFAFHLLIVNHRQNEIIRKQNSVLEQYLTQIERVTLLEERDRLSKDLHDTMG 197 Query: 203 HSYTSIILGLETLKPHVASQEGEHKLQGVLELARKGLDDVRLQVHQMDPLEEPVTLDRAL 262 HSY SII+G+ETL+ +ASQEG KL+ +L+LARKG+ +VR +HQM +E + L +L Sbjct: 198 HSYVSIIMGMETLRQDIASQEGVQKLESLLQLARKGMKEVRGYLHQMGSPQETLPLGHSL 257 Query: 263 MQIAGQFESNTGVTLSFRTMGEPYAVIKQAKHTLSRSLQEALTNASRHGQASAIRVVLQY 322 Q+A +F+++ V + FR +GE Y V KQ K TL R LQE+LTNA RHG A+ I V L + Sbjct: 258 RQLAEEFQTHAKVNVRFRAIGEEYPVGKQVKMTLFRCLQESLTNAVRHGHATDIVVSLHF 317 Query: 323 DPAQLMLQIQDNGKGTAQLRYGFGLTGMKERLAALQGKLYIDSQENDGTLVTCIIPNQTQ 382 + Q L++QDNG G GFG+T MKER A LQG++ + S+ +GTLVTC++P + Sbjct: 318 EQQQTRLEVQDNGHGVENWEDGFGITTMKERAAHLQGRVSVFSERGEGTLVTCLVPRMVE 377 Query: 383 EGERRIDILLADDQPLVRESLRLLLGEEKDFR-LRTAASGKQALEQCAAEQPDIVLMDIH 441 + I +++ DD +RESLR +L ++D R + A G QA+E C +PD+VLMD+ Sbjct: 378 SADEIIRLVIVDDHSFIRESLRSILEGQRDLRVVGLAEDGAQAVELCEELEPDLVLMDLE 437 Query: 442 MPEMDGLEATRQLKEKWPEVRVIIITTFEEITYAAEALRLGAEGYLLKTLHPKELAATIR 501 MP MDG+ AT+++KEKWP +R+++++TF++ A E +R GA+GYLLK++ +ELA TIR Sbjct: 438 MPNMDGITATKRIKEKWPGIRILVLSTFQDTEKAKEIMRSGADGYLLKSIESRELAETIR 497 Query: 502 LIYGGGTMISQEVAQQLFQDQ-------------QLEAPLNPYDLTERELEVLQELTEGL 548 L++ GGTMI+Q++ ++ Q Q E N Y LT+RE E+LQ L +G+ Sbjct: 498 LVHRGGTMIAQDLFHKMLDGQPVNGQEDLLVAPKQSEKDENAYGLTKREQEILQMLAQGM 557 Query: 549 RNKQIAQKLHLSEGTVRNYISAIYLKLQVGDRDEAVEKSKKEQLV 593 R K IA KL+LS+GTVRNY SA+Y KL V +RD+AV+K K E LV Sbjct: 558 RYKTIASKLYLSDGTVRNYASALYDKLGVRNRDDAVQKGKMEGLV 602 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,014,311,610 Number of extensions: 112850340 Number of successful extensions: 434722 Number of sequences better than 1.0e-05: 27410 Number of HSP's gapped: 427960 Number of HSP's successfully gapped: 27475 Length of query: 601 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 459 Effective length of database: 1,722,912,073 Effective search space: 790816641507 Effective search space used: 790816641507 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)