BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0062.p (270 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0ZKG8.1 C0ZKG8_BREBN Two-component response regulator 325 2e-87 A3IAJ2.1 A3IAJ2_9BACI Two-component response regulator 305 3e-81 A7GM21.1 A7GM21_BACCN Two component transcriptional regulator, w... 281 5e-74 Q09KJ4.1 Q09KJ4_BACCE Two-component response regulator 280 7e-74 C3BH28.1 C3BH28_9BACI Two-component response regulator 280 8e-74 >C0ZKG8.1 C0ZKG8_BREBN Two-component response regulator Length = 241 Score = 325 bits (834), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 160/255 (62%), Positives = 192/255 (75%), Gaps = 21/255 (8%) Query: 7 MNHAAILLVDDEESIIGLIKTVLYKEGFTDIDSAGTGEAAILACQSKVYDLIVLDVMLPG 66 M AAILLVDDE++I+ L++TVL+KEGF ID T E A+ AC+ K YDLIVLDV LP Sbjct: 1 MKDAAILLVDDEQAILQLLETVLHKEGFHSIDKVKTSEEALCACERKSYDLIVLDVTLPN 60 Query: 67 RSGIDICPFLRQTTNAPVLFLSARTSDFDKLTGFAVGGDDYMTKPFNPLELVARIRSQLR 126 SGI+ CPF+R+ T+AP+LFLSAR +DFDKLTGFAVGGDDY+TKPFNP+E+VARI++ LR Sbjct: 61 MSGIEACPFIRRLTDAPILFLSARDTDFDKLTGFAVGGDDYVTKPFNPMEIVARIKALLR 120 Query: 127 RYLGMVGGPEPAQVNALHKQPSEANDRQGRQPVQHHLRYDFGRFQVDEAAGELRVEGEVV 186 R A V + YDFGRFQV EAAGEL VEG+V+ Sbjct: 121 RTRKTSAAVPTAPVQGV---------------------YDFGRFQVHEAAGELCVEGKVI 159 Query: 187 ACPALVFQLLLFFCKHPNRLFTKSELYERVWGEDALSDDNTVMVHIHRIRERIELEPANP 246 CP+LVFQLLLF CK+PNR+F+KSELYERVWG ++L DDNT+MVHIHRIRERIE +PA P Sbjct: 160 PCPSLVFQLLLFLCKNPNRIFSKSELYERVWGVNSLRDDNTIMVHIHRIRERIEPDPAQP 219 Query: 247 VFLVNVRGLGYKLVQ 261 FLVNVRGLGYK+V+ Sbjct: 220 EFLVNVRGLGYKMVK 234 >A3IAJ2.1 A3IAJ2_9BACI Two-component response regulator Length = 256 Score = 305 bits (781), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 144/253 (56%), Positives = 188/253 (74%), Gaps = 19/253 (7%) Query: 12 ILLVDDEESIIGLIKTVLYKEGFTDIDSAGTGEAAILACQSKVYDLIVLDVMLPGRSGID 71 ILLVDDE +I+ +++ VL KEGF ID A T + A+ AC K YD+I+LDVMLP RSG D Sbjct: 21 ILLVDDESAILDMLQMVLTKEGFRQIDRASTAQEALNACNKKPYDMILLDVMLPDRSGFD 80 Query: 72 ICPFLRQTTNAPVLFLSARTSDFDKLTGFAVGGDDYMTKPFNPLELVARIRSQLRRYLGM 131 ICPF+R+TT AP+LF++A+ SD +KLTGFA+GGDDY+TKPFNPLE+VAR+++QLRR + + Sbjct: 81 ICPFIRETTEAPILFITAKNSDLEKLTGFAMGGDDYITKPFNPLEIVARMKAQLRR-VKL 139 Query: 132 VGGPEPAQVNALHKQPSEANDRQGRQPVQHHLRYDFGRFQVDEAAGELRVEGEVVACPAL 191 P +++ + YDFGRFQV+E AGEL V+G+V++CPA Sbjct: 140 YEEERPLHLSS------------------NMFIYDFGRFQVNERAGELMVDGQVISCPAQ 181 Query: 192 VFQLLLFFCKHPNRLFTKSELYERVWGEDALSDDNTVMVHIHRIRERIELEPANPVFLVN 251 V+QLLLFFCKHPN++FTKS+LYE VWG+ + DDNTV VHI RIRERIE +P +P L+ Sbjct: 182 VYQLLLFFCKHPNQIFTKSQLYEAVWGDHSFGDDNTVTVHIGRIRERIEKDPKDPELLLT 241 Query: 252 VRGLGYKLVQHSG 264 +RGLGYKL+Q G Sbjct: 242 IRGLGYKLIQKEG 254 >A7GM21.1 A7GM21_BACCN Two component transcriptional regulator, winged helix family Length = 235 Score = 281 bits (719), Expect = 5e-74, Method: Compositional matrix adjust. Identities = 133/255 (52%), Positives = 180/255 (70%), Gaps = 24/255 (9%) Query: 7 MNHAAILLVDDEESIIGLIKTVLYKEGFTDIDSAGTGEAAILACQSKVYDLIVLDVMLPG 66 M +A ILLVDDE +I+ L+ T+L KEGF+ I +A + E A+L + YDL++LDVMLPG Sbjct: 1 MYNANILLVDDESAILQLLTTILQKEGFSHITTATSAEEALLLVEDHSYDLMILDVMLPG 60 Query: 67 RSGIDICPFLRQTTNAPVLFLSARTSDFDKLTGFAVGGDDYMTKPFNPLELVARIRSQLR 126 +SG DICP +RQ T+ P+ FL+A+TSD DK++GF G DDY+TKPFNPLE+VAR+++QLR Sbjct: 61 QSGFDICPIIRQKTDCPIFFLTAKTSDLDKVSGFLYGADDYITKPFNPLEVVARMKAQLR 120 Query: 127 RYLGMVGGPEPAQVNALHKQPSEANDRQGRQPVQHHLRYDFGRFQVDEAAGELRVEGEVV 186 R+L P+ Q + + Y FGRFQVD+ A EL+V+G +V Sbjct: 121 RHLKYT--PKTIQTSDI---------------------YSFGRFQVDKHAAELKVDGNIV 157 Query: 187 ACPALVFQLLLFFCKHPNRLFTKSELYERVWGEDALS-DDNTVMVHIHRIRERIELEPAN 245 C A +FQLLLFFC+HPN +F+K E+YE+VWG A + DDNTVMVHI ++RE+IE P+N Sbjct: 158 ECSAQLFQLLLFFCEHPNYVFSKEEIYEKVWGAPAYNGDDNTVMVHIRKLREKIEFNPSN 217 Query: 246 PVFLVNVRGLGYKLV 260 P ++ VRGLGYK + Sbjct: 218 PQYIKTVRGLGYKFI 232 >Q09KJ4.1 Q09KJ4_BACCE Two-component response regulator Length = 235 Score = 280 bits (717), Expect = 7e-74, Method: Compositional matrix adjust. Identities = 132/255 (51%), Positives = 180/255 (70%), Gaps = 24/255 (9%) Query: 7 MNHAAILLVDDEESIIGLIKTVLYKEGFTDIDSAGTGEAAILACQSKVYDLIVLDVMLPG 66 M +A ILLVDDE +I+ L+ T+L KEGF+ I +A + E A+L + YDL++LDVMLPG Sbjct: 1 MYNANILLVDDESAILQLLTTILQKEGFSHITTATSAEEALLLVEDHSYDLMILDVMLPG 60 Query: 67 RSGIDICPFLRQTTNAPVLFLSARTSDFDKLTGFAVGGDDYMTKPFNPLELVARIRSQLR 126 +SG DICP +RQ T+ P+ FL+A+TSD DK++GF G DDY+TKPFNPLE+VAR+++QLR Sbjct: 61 QSGFDICPIIRQKTDCPIFFLTAKTSDLDKVSGFLYGADDYITKPFNPLEVVARMKAQLR 120 Query: 127 RYLGMVGGPEPAQVNALHKQPSEANDRQGRQPVQHHLRYDFGRFQVDEAAGELRVEGEVV 186 R+L P+ Q + + Y FGRFQ+D+ A EL+V+G +V Sbjct: 121 RHLKYT--PKTIQTSDI---------------------YSFGRFQIDKHAAELKVDGNIV 157 Query: 187 ACPALVFQLLLFFCKHPNRLFTKSELYERVWGEDALS-DDNTVMVHIHRIRERIELEPAN 245 C A +FQLLLFFC+HPN +F+K E+YE+VWG A + DDNTVMVHI ++RE+IE P+N Sbjct: 158 ECSAQLFQLLLFFCEHPNYVFSKEEIYEKVWGAPAYNGDDNTVMVHIRKLREKIEFNPSN 217 Query: 246 PVFLVNVRGLGYKLV 260 P ++ VRGLGYK + Sbjct: 218 PQYIKTVRGLGYKFI 232 >C3BH28.1 C3BH28_9BACI Two-component response regulator Length = 234 Score = 280 bits (717), Expect = 8e-74, Method: Compositional matrix adjust. Identities = 130/255 (50%), Positives = 182/255 (71%), Gaps = 24/255 (9%) Query: 7 MNHAAILLVDDEESIIGLIKTVLYKEGFTDIDSAGTGEAAILACQSKVYDLIVLDVMLPG 66 M +A +LLVDDE +I+ L+ T+L KEGF+ I +A + E A+ + YDL++LDVMLPG Sbjct: 1 MYNANVLLVDDETAILQLLTTILQKEGFSHITTATSAEEALQFVEQNRYDLMILDVMLPG 60 Query: 67 RSGIDICPFLRQTTNAPVLFLSARTSDFDKLTGFAVGGDDYMTKPFNPLELVARIRSQLR 126 +SG DICP +RQ T+ P+ FL+A++SD DK++GF G DDY+TKPFNPLE+VAR+++QLR Sbjct: 61 QSGFDICPIIRQKTDCPIFFLTAKSSDLDKVSGFLYGADDYITKPFNPLEVVARMKAQLR 120 Query: 127 RYLGMVGGPEPAQVNALHKQPSEANDRQGRQPVQHHLRYDFGRFQVDEAAGELRVEGEVV 186 R++ +Q QP++ FGRFQVD+ A EL+V+G++V Sbjct: 121 RHM-----------------------KQTTQPMKETHFLSFGRFQVDKHAAELQVDGKIV 157 Query: 187 ACPALVFQLLLFFCKHPNRLFTKSELYERVWGEDALS-DDNTVMVHIHRIRERIELEPAN 245 C A +FQLLLFFC+HPN +F+K E+YE+VWG A + DDNTVMVHI ++RE+IEL+P+N Sbjct: 158 ECSAQLFQLLLFFCEHPNYVFSKEEIYEKVWGAPAYNGDDNTVMVHIRKLREKIELDPSN 217 Query: 246 PVFLVNVRGLGYKLV 260 P ++ VRGLGYK + Sbjct: 218 PQYIKTVRGLGYKFI 232 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.322 0.140 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,700,125,790 Number of extensions: 73344765 Number of successful extensions: 234479 Number of sequences better than 1.0e-05: 21420 Number of HSP's gapped: 218374 Number of HSP's successfully gapped: 22442 Length of query: 270 Length of database: 3,060,696,203 Length adjustment: 133 Effective length of query: 137 Effective length of database: 1,807,701,208 Effective search space: 247655065496 Effective search space used: 247655065496 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 130 (54.7 bits)