BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0022.p (227 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A9VUN3.1 A9VUN3_BACWK Transcriptional regulator, TetR family 417 e-115 B1D535.1 B1D535_9BACL Transcriptional regulator, TetR family 401 e-110 C2C1L1.1 C2C1L1_LISGR Transcription regulator 101 6e-20 Q9CFG3.1 Q9CFG3_LACLA Transcriptional regulator 99 2e-19 Q837P6.1 Q837P6_ENTFA Transcriptional regulator, TetR family 89 4e-16 >A9VUN3.1 A9VUN3_BACWK Transcriptional regulator, TetR family Length = 238 Score = 417 bits (1071), Expect = e-115, Method: Compositional matrix adjust. Identities = 203/231 (87%), Positives = 214/231 (92%), Gaps = 6/231 (2%) Query: 2 MKKQQPQISEDRILEASWELLGEEDIEKFSMRRLADRLGIQAPSLYWYFKSKQNLYQRLA 61 MKKQQPQISED+ILEASWELLGEE IEK SMRRLADRLGIQAPSLYWYFKSKQNLYQRLA Sbjct: 7 MKKQQPQISEDKILEASWELLGEEGIEKLSMRRLADRLGIQAPSLYWYFKSKQNLYQRLA 66 Query: 62 NQVSKIILEEFHSEGDWKEQLTGLAVTVRSVLSRYPCSTQLMMMTLPHEPDIIRFTNRML 121 NQVSKIILEEFHSEGDWKEQL+ LAVTVRSVLSRYPCSTQ+MMMTLPHEPDIIRFTNRML Sbjct: 67 NQVSKIILEEFHSEGDWKEQLSELAVTVRSVLSRYPCSTQIMMMTLPHEPDIIRFTNRML 126 Query: 122 LCVESTPLEQAQKMQVVTTLVNYVFYFVLDDYQHERNVSAILK------EQGAAPGEEVI 175 LCVESTPLEQ QKMQVVTTLVNYV+YFVLDDYQH+RNVSAILK + PGEE+I Sbjct: 127 LCVESTPLEQEQKMQVVTTLVNYVYYFVLDDYQHQRNVSAILKVNETLPGEEMIPGEEMI 186 Query: 176 RLLDSMSDTDAGLFRRLFTNGLFELMGTDGAFEFGLKLILLGIEQVIKEQA 226 RLLDSM++TDAGLFRR+FTNGLFELMGTD AFEFGL LILLG+EQVIKEQ Sbjct: 187 RLLDSMNETDAGLFRRMFTNGLFELMGTDRAFEFGLNLILLGVEQVIKEQV 237 >B1D535.1 B1D535_9BACL Transcriptional regulator, TetR family Length = 230 Score = 401 bits (1031), Expect = e-110, Method: Compositional matrix adjust. Identities = 190/223 (85%), Positives = 207/223 (92%) Query: 3 KKQQPQISEDRILEASWELLGEEDIEKFSMRRLADRLGIQAPSLYWYFKSKQNLYQRLAN 62 K++QPQISED+ILEASWELLGEE +EKFSMRRLADRLGIQAPSLYWYFKSKQNLYQRLAN Sbjct: 4 KQKQPQISEDKILEASWELLGEEGMEKFSMRRLADRLGIQAPSLYWYFKSKQNLYQRLAN 63 Query: 63 QVSKIILEEFHSEGDWKEQLTGLAVTVRSVLSRYPCSTQLMMMTLPHEPDIIRFTNRMLL 122 QVSKIILEEFHS+GDWK QL GLAVTVR VL RYPCSTQLMMMTLPHEPDIIRFTNRMLL Sbjct: 64 QVSKIILEEFHSDGDWKGQLAGLAVTVRIVLRRYPCSTQLMMMTLPHEPDIIRFTNRMLL 123 Query: 123 CVESTPLEQAQKMQVVTTLVNYVFYFVLDDYQHERNVSAILKEQGAAPGEEVIRLLDSMS 182 CVESTPL+Q QK+Q + T++NYVFYFVLDDY+H+RNV+AIL EQG P E++ LLDSMS Sbjct: 124 CVESTPLDQEQKLQAILTVMNYVFYFVLDDYEHQRNVTAILMEQGEMPSGEMMDLLDSMS 183 Query: 183 DTDAGLFRRLFTNGLFELMGTDGAFEFGLKLILLGIEQVIKEQ 225 +TDAGLFRR+F NGLFELMGTDGAFEFGLKLIL GIEQVIKEQ Sbjct: 184 ETDAGLFRRMFKNGLFELMGTDGAFEFGLKLILSGIEQVIKEQ 226 >C2C1L1.1 C2C1L1_LISGR Transcription regulator Length = 207 Score = 101 bits (251), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 65/220 (29%), Positives = 112/220 (50%), Gaps = 17/220 (7%) Query: 2 MKKQQPQISEDRILEASWELLGEEDIEKFSMRRLADRLGIQAPSLYWYFKSKQNLYQRLA 61 MKKQ+ Q +I A+W+LL FSMR+LA+ +G+ SLY++F SK+ L+ L Sbjct: 1 MKKQETQ---KKITNAAWKLLQSHGTNGFSMRKLAELVGMTVSSLYYHFPSKEALFAELI 57 Query: 62 NQVSKIILEEFHSEGDWKEQLTGLAVTVRSVLSRYPCSTQLMMMTLPHEPDIIRFTNRML 121 N S+ IL E WK +L A + + L YP QL+M P + ++ + +L Sbjct: 58 NHASEEILFPV-EERTWKGRLEKYAHHILTTLDHYPGLAQLLMDYPPSSRNYLKLLDTLL 116 Query: 122 LCVESTPLEQAQKMQVVTTLVNYVFYFVLDDYQHERNVSAILKEQGAAPGEEVIRLLDSM 181 + + +E +K + +NY+ F +D + ++ + +E+ EE + L + Sbjct: 117 MTLSDLTMEPEEKFFAINAYMNYICTFKIDSERFQKRDNRFTEEE-----EESYKFLPFL 171 Query: 182 SDTDAGLFRRLFTNGLFELMGTDGAFEFGLKLILLGIEQV 221 + G+F+ +G+ FEFGL+LIL G+E++ Sbjct: 172 TAYKKA--------GIFDRLGSPFMFEFGLQLILSGMEKI 203 >Q9CFG3.1 Q9CFG3_LACLA Transcriptional regulator Length = 208 Score = 99.4 bits (246), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 68/221 (30%), Positives = 118/221 (53%), Gaps = 23/221 (10%) Query: 8 QISEDRILEASWELLGEEDIEKFSMRRLADRLGIQAPSLYWYFKSKQNLYQRLANQVS-K 66 Q ++D+I+ +SWELL E + +FSMR+LA RLG+ SLY++F SK+ L+ L ++ S + Sbjct: 4 QPTKDKIISSSWELLEELTLTEFSMRKLASRLGMTVSSLYYHFSSKEALFAELIDKASLE 63 Query: 67 IILEEFHSEGDWKEQLTGLAVTVRSVLSRYPCSTQLMMMTLPHEPDIIRFTNRMLLCVES 126 II +E W+++L + +VL YP QLMM P + +R +++L+ V+ Sbjct: 64 IIFPA--NEKTWQDRLFVYGKNIYTVLESYPNLAQLMMDYPPESENYLRLFDKLLMIVDD 121 Query: 127 TPLEQAQKMQVVTTLVNYVFYFVLDD----YQHERNVSAILKEQGAAPGEEVIRLLDSMS 182 L K + +N+++ +D QHE+ +S + P ++ LD Sbjct: 122 LKLSDDHKFYTINLFLNFIYTSKIDSDRLVEQHEKPLSTV-----KIPLVQLAPFLDKYW 176 Query: 183 DTDAGLFRRLFTNGLFELMGTDGAFEFGLKLILLGIEQVIK 223 T++ +G+ +FEFGL+LI+ GIE+++K Sbjct: 177 RTES-----------LTSLGSSESFEFGLQLIISGIEKMLK 206 >Q837P6.1 Q837P6_ENTFA Transcriptional regulator, TetR family Length = 220 Score = 88.6 bits (218), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 53/185 (28%), Positives = 98/185 (52%), Gaps = 11/185 (5%) Query: 6 QPQISEDRILEASWELLGEE-DIEKFSMRRLADRLGIQAPSLYWYFKSKQNLYQRLANQV 64 +P++S+D I+ A++ LL + +E+ SMR++A +LG+QAP++YWYFK+KQ L Q +A + Sbjct: 2 EPKLSKDTIIAAAFSLLEKSPTLEQLSMRKVAKQLGVQAPAIYWYFKNKQALLQSMAEAI 61 Query: 65 SKIILEEFHSE----GDWKEQLTGLAVTVRSVLSRYPCSTQLMMMTLPHEPDIIRFTNRM 120 EE E G+W L + ++PC+ + + T+P P +R N+M Sbjct: 62 -----EEHFQEPALCGEWYSDLLAFMENYYDLYQQFPCAVAIEIQTVPAYPQRLRHLNQM 116 Query: 121 LLCVESTPLEQAQKMQVVTTLVNYVFYFVLDDYQHERNVSAILKEQGAAPGEEVIRLLDS 180 + + VT+L + +F ++D + ++ VS +L E+V+ + Sbjct: 117 MGILREAGFSPEMTHLAVTSLQHLLFGMIMDATEEKQLVSQVLNGDDYL-KEQVLHMKQY 175 Query: 181 MSDTD 185 +SD + Sbjct: 176 VSDNE 180 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.136 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,272,625,847 Number of extensions: 48992780 Number of successful extensions: 164611 Number of sequences better than 1.0e-05: 303 Number of HSP's gapped: 164656 Number of HSP's successfully gapped: 303 Length of query: 227 Length of database: 3,060,696,203 Length adjustment: 131 Effective length of query: 96 Effective length of database: 1,826,543,238 Effective search space: 175348150848 Effective search space used: 175348150848 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 129 (54.3 bits)