BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0599.0018.p (537 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C5EPZ4.1 C5EPZ4_9FIRM Two component transcriptional regulator 184 2e-44 Q2BFM0.1 Q2BFM0_9BACI AraC-type DNA-binding domain-containing pr... 166 7e-39 A9QDR4.1 A9QDR4_9BACL YesN 162 7e-38 A8RTG7.1 A8RTG7_9CLOT Putative uncharacterized protein 155 1e-35 B1DHI6.1 B1DHI6_9BACL Two component transcriptional regulator, A... 151 2e-34 >C5EPZ4.1 C5EPZ4_9FIRM Two component transcriptional regulator Length = 517 Score = 184 bits (467), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 149/533 (27%), Positives = 268/533 (50%), Gaps = 36/533 (6%) Query: 13 KLFIADDEQLVVETLSEMIDWDAFGVRIIGTANNGKQALERILQSDPDIVLTDIRMPGLN 72 KL IADDE+L E + + +D G+ + A++G LE L+ PDIVLTDIRMP +N Sbjct: 2 KLLIADDEKLTREGIRDRLDLQGLGISGVFLADDGVHGLETALKESPDIVLTDIRMPRMN 61 Query: 73 GLDLIRTLKENGRKAECIIVSGYSEFEYAKEAIELEAVDYLIKPAELDEVARTVSRAIQR 132 G+ + + I +S YS+ EY K AI+L+AV Y+ KP +++E+ + + A++ Sbjct: 62 GVQMAEQILSANPGTVIIFMSAYSDKEYLKAAIKLKAVSYVEKPLDMEELKQALGEAVET 121 Query: 133 LGRKADQTGNHPELRIAKALDR---AVFTDLIVHGKRPSFDQT---------PYGQYDQF 180 R+ T L +++ ++ T L+ + S D+ P F Sbjct: 122 --RRTMST----HLAASRSHEKEQLGHLTLLLTEPEPESLDEAGELIGSLGLPINSSTCF 175 Query: 181 AVILIGS--PATLLLERMKDKGIADALLSFLANRGIVVDLLYEQQKVILLCMANLKEDAP 238 + +L+ S P TLL E D+ + D+ S LA+RGI + I++ L DA Sbjct: 176 SALLLDSQTPVTLLPENRMDE-VRDSFSSMLADRGIGQMYFIRADRYIIIF---LYSDAR 231 Query: 239 LTETLIAAAATFSNDGSWDDTLMSFAIGPVVTEIMHMHVSYLAAYKACQMGLF--FGAPV 296 E LI A F + + + ++GPVV+ + H+SY+ A + + F +G + Sbjct: 232 QEEKLIHDCAAFLSKQLNEISRFFVSVGPVVSGMERAHISYMEAKEHLKESFFHEYGF-I 290 Query: 297 MDASSWTEITRISERIVSDWSNQIQSFIRYEQKEFEAMLERWTEWGTKQLIAPDTLKKTG 356 +D + ++ ++S + + E + + + + + ++ P +K Sbjct: 291 LDKDTANAPFHPPADVLLEFSMALAE--KQEDQALKLAGQLYQSFVPNDVLGPSQVKDIY 348 Query: 357 AQWANRLHDLIGQDYGIKIERVTGDRTRLIEEIHEAPDWASLKKICVDL--AQSVQFYLN 414 ++ ++L D G + I + + G T I E A+LK++ DL A++ QF+ Sbjct: 349 YKYLSKL-DEHGMNNYISLWQKEGLNTESIWE--GVMGCATLKELH-DLLCAKTRQFFEQ 404 Query: 415 VTKTTLKEKVVHEIKAYLESHY-HENIQLDQLAERFDLNASYVSNLYSKSTGQTILEYVT 473 + + + VV +IK +++ +Y ++ + ++E L+ SYV ++ TGQT+ +Y+T Sbjct: 405 LEDSQGENPVVFQIKEFIQQNYAAPSLSVPDVSEHVHLSPSYVCTVFKNETGQTLNQYLT 464 Query: 474 LLRIRQAKKMLRGSSFKISKISTNVGYDNQRYFCQVFKKHVGVSPSQYREEHM 526 RI+ +K+ L +KI+ IS+ VGY + Y+ + FKK VG+SPS+YRE+ + Sbjct: 465 DYRIKMSKQFLSDPRYKIADISSKVGYSDGNYYSKAFKKIVGLSPSEYREKML 517 >Q2BFM0.1 Q2BFM0_9BACI AraC-type DNA-binding domain-containing proteins Length = 520 Score = 166 bits (419), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 143/545 (26%), Positives = 262/545 (48%), Gaps = 59/545 (10%) Query: 11 LYKLFIADDEQLVVETLSEMIDWDAFGVRIIGTANNGKQALERILQSDPDIVLTDIRMPG 70 +YK+ I DDE ++ + LSE IDW + I G A NG + I + PDI+++DI MPG Sbjct: 1 MYKVLIIDDEPMITKGLSEKIDWASLDCMIQGIAMNGLEGKRMIDELRPDIIVSDIVMPG 60 Query: 71 LNGLDLIRTLKENGRKAECIIVSGYSEFEYAKEAIELEAVDYLIKPAELDEVARTVSRAI 130 GL+L + ++ + I++SG+ EF +AKEA++ DYL+KP +EV + A+ Sbjct: 61 CTGLELASYVHQHYKNTIIILLSGHDEFTFAKEALKYSVFDYLLKPTIKEEVMNVIRNAV 120 Query: 131 QRLGRKADQTGNHPELRIA-----KALDRAVFTDLIVHGKRPSFDQTPYGQYDQFAVILI 185 + + K +Q N+ L A +++++ D+ V G S D + + F + Sbjct: 121 KNIEEKREQDKNYQYLESALQENIPLIEQSLLYDITVKGTVHSKDLR--DKIESFHLTF- 177 Query: 186 GSPATLLLE-RMKDKGIADALLS------FLANRGIVVDLLYEQQKVILLCMANLKEDAP 238 G A L +E ++ A + +S L I + ++I+L + + Sbjct: 178 GKGAVLTIEVDAYEENQAPSPISIRYIEEILKKNNITARYVANDNQIIILPSFPIGVPSK 237 Query: 239 LTETLIAAAATFSND--GSWDDTLMSFAIGPVVTEIMHMHVSYLAAYKACQMGLFFG--- 293 + ET + + D + D +S IG + + + +H SYL + +A + F G Sbjct: 238 VLETRVRDVSDKIMDRLKAIDHLSVSIGIGGIYSSVNSLHSSYLQSAEALKRSYFAGKGK 297 Query: 294 APVMDASSWTEITRISERIVSDWSNQIQSFIR-YEQKEFEAMLERWTEWGT-------KQ 345 + D R SE +N ++SFI+ +E++ E +LE + KQ Sbjct: 298 VHIFDDQK----QRHSE---VKNTNSLESFIQSFEERSLERILEEYELLFKELKYTYDKQ 350 Query: 346 LIAPDTLKKTG------AQWANRLHDLIGQDYGIKIERVTGDRTRLIEEIHEAPDWASLK 399 I L+ ++W +G YG ++E+ T I E D+ +K Sbjct: 351 FILNQCLELLIKLGLLVSKWDKHFKISVG--YG-QLEKCTS--------IDELQDF--MK 397 Query: 400 KICVDLAQSVQFYLNVTKTTLKEKVVHEIKAYLESHY-HENIQLDQLAERFDLNASYVSN 458 K+ + + Y +++ + +V + K +E Y + ++ +A++ D+N SY+S Sbjct: 398 KVIIQIKD--HLYEEMSENNI--GIVEQAKKIIEQQYDNPDLSAQYMADKLDVNVSYLSR 453 Query: 459 LYSKSTGQTILEYVTLLRIRQAKKMLRGSSFKISKISTNVGYDNQRYFCQVFKKHVGVSP 518 + K TG+ ++ +VT R++ A+K+L + K ++++ VG+ + RYF QVFKK + +P Sbjct: 454 TFKKETGENLINFVTEKRMQMAQKLLDTTDLKTNEVAKRVGFIDARYFGQVFKKFMSTTP 513 Query: 519 SQYRE 523 SQY++ Sbjct: 514 SQYKK 518 >A9QDR4.1 A9QDR4_9BACL YesN Length = 522 Score = 162 bits (411), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 150/547 (27%), Positives = 255/547 (46%), Gaps = 55/547 (10%) Query: 11 LYKLFIADDEQLVVETLSEMIDWDAFGVRIIGTANNGKQALERILQSDPDIVLTDIRMPG 70 +YK+ + DDE V + L +IDW++ G I A NG++ALE+I PD+V+ DIRMP Sbjct: 1 MYKVLLVDDEIFVRKGLRNLIDWESLGYEICDEAGNGQEALEKIQLIKPDLVIADIRMPV 60 Query: 71 LNGLDLIRTLKENGRKAEC-IIVSGYSEFEYAKEAIELEAVDYLIKPAELDEVARTVSRA 129 L+GL+LIR + E G + IIVSGY +F+YA+ A+ DY++KP + E+ T+ Sbjct: 61 LDGLELIRKVTEEGVHSPTFIIVSGYHDFQYAQRALRYGVHDYILKPIDEAELETTLKAL 120 Query: 130 IQRLGRKADQTGNHPEL---RIAKALDRAVFTDLIVHGKRPSFDQTPYGQYDQFAVILIG 186 LG K T L I + L + F++ + + +D V L Sbjct: 121 SGTLGLKKLATIAGDSLVTDSIVETLVQGQFSEADNGALCAALQMPEFSSFDYVLVELHA 180 Query: 187 SPATLLLERMKDKGIADALLSFLANRGIVVDLLYEQQKVILLCMANLKEDAPLTETLIAA 246 S + E + K +A + S A + + YEQ + + + K P L +A Sbjct: 181 SAQSAGTE-WQAKELAAVVQSVSATPSSKIPV-YEQTSGLFGLLIDRKPFLPPEIRLESA 238 Query: 247 -----AATFSNDGSWDDTLMSFAIGPVVTEIMHMHVSYLAA-----YKACQMGLFF---- 292 AA + G ++ IG V + M +SY AA YK + G Sbjct: 239 YNSLHAAIAKSSGRP----VTLYIGKTVERLQEMCLSYRAANEAMSYKYAEQGSSVIYAN 294 Query: 293 ---GAPVMDASSWTEI-TRISERIVSDWSNQIQSFIRYEQKEFEAMLERWTEWGTKQLIA 348 G P+ +E+ +R+ ER+ + ++ YEQ + E + ++ E + A Sbjct: 295 QVQGTPLYYFDVDSELYSRLLERLEENNAD------LYEQ-DIELLFRQFVE----KRFA 343 Query: 349 PDTLKKTGAQWANRLHDLIGQDYGIKIERVTGDRTRLIEEIHEAPDWAS-------LKKI 401 P+ + T ++ + ++I ++ GD L ++ DW LK + Sbjct: 344 PNAVANTITRFVIGIINII--------RKMEGDEKGL-SKLPFIMDWQGSNSRLQDLKGL 394 Query: 402 CVDLAQSVQFYLNVTKTTLKEKVVHEIKAYLESHYHENIQLDQLAERFDLNASYVSNLYS 461 D + YL + + + IK Y+E++Y ENI L +A +F +N+ Y+ L+ Sbjct: 395 FTDFLREAAVYLAELRNEQSKGGIERIKKYIEANYTENISLKSIAGKFYMNSVYLGQLFR 454 Query: 462 KSTGQTILEYVTLLRIRQAKKMLRGSSFKISKISTNVGYDNQRYFCQVFKKHVGVSPSQY 521 K+ G +++ +RI +AKK+LR + ++ +I+ VG+ N YF F+K V+P+ Y Sbjct: 455 KTYGIYFNDFLLQIRIGEAKKLLRQTDLRMYEIAEKVGFQNADYFVTQFEKLEKVTPTDY 514 Query: 522 REEHMIK 528 R + + K Sbjct: 515 RNKLLGK 521 >A8RTG7.1 A8RTG7_9CLOT Putative uncharacterized protein Length = 518 Score = 155 bits (391), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 135/527 (25%), Positives = 260/527 (49%), Gaps = 24/527 (4%) Query: 13 KLFIADDEQLVVETLSEMIDWDAFGVRIIGTANNGKQALERILQSDPDIVLTDIRMPGLN 72 KL I DDE+L E + + + ++ G+ + ++G L+ L+ PDIVLTD+RMP +N Sbjct: 2 KLLIVDDEKLTREGIRDSLGLESLGISQVLLEDDGIHGLKTALEERPDIVLTDVRMPRMN 61 Query: 73 GLDLIRTLKENGRKAECIIVSGYSEFEYAKEAIELEAVDYLIKPAELDEVARTVSRAI-- 130 G+ + + + I +S YS+ EY K AI+L+A+ Y+ KP +++E+A V A+ Sbjct: 62 GVQMAERILKELPGTSIIFMSAYSDKEYLKAAIKLKALGYVEKPLDMEELASAVKEAVDS 121 Query: 131 ---QRLGRKADQTGNHPEL-RIAKALDRAVFTDLIVHGKRPSFDQTPYGQYDQFAVILIG 186 +++ + A + +L ++ L + LI G+ + F I+I Sbjct: 122 SRNEKISQAAARLQEKEQLGHLSLLLSQPEEESLIKAGQLAADLGLSITHTTCFCCIIID 181 Query: 187 --SPATLLLERMKDKGIADALLSFLANRGIV-VDLLYEQQKVILLCMANLKEDAPLTETL 243 +P + L E D GI D + +L + I +L ++I+ + ++ P +TL Sbjct: 182 CVTPLSALPEEQMD-GIRDYFMEYLTSMDISQAYVLRGDHRIIVFLHSPVR---PADKTL 237 Query: 244 IAAAATFSNDGSWDDTLMSFAIGPVVTEIMHMHVSYLAAYKACQMGLF--FGAPVMDASS 301 A + ++GPVV+ + H+SY A + + F +G ++ + Sbjct: 238 YDCAGLLAQK-LIKICPFFISLGPVVSGMDRAHLSYQEASEHLKEAFFHDYGF-ILTRNM 295 Query: 302 WTEITRISERIVSDWSNQIQSFIRYEQKEFEAMLERWTEWGTKQLIAPDTLKKTGAQWAN 361 T + R ++ ++S + + E++ + + + + +I P +K ++ + Sbjct: 296 ETAVFRPPADLLLEFSMALSE--KQEEEALDIVRRLYESFVPNDMIGPSQVKDIYYKYFS 353 Query: 362 RLHDLIGQDYGIKIERVTGDRTRLIEEIHEAPDWASLKKICVDLAQSVQ-FYLNVTKTTL 420 +L D G I + + G + I E + L+++ LA V+ F+ + ++ Sbjct: 354 KL-DEHGLGSYISLWQKEGLESESIWE--GVMNCTILRELNDLLAAKVRLFFERLRGNSV 410 Query: 421 KEKVVHEIKAYLESHYHE-NIQLDQLAERFDLNASYVSNLYSKSTGQTILEYVTLLRIRQ 479 VV +IK Y+ +Y ++ + ++E L++SYV ++ TGQT+ +Y+T RI+ Sbjct: 411 GNPVVFQIKEYIHKNYAVLSLSVPDVSEYVRLSSSYVCTIFKNETGQTLNQYLTDYRIKM 470 Query: 480 AKKMLRGSSFKISKISTNVGYDNQRYFCQVFKKHVGVSPSQYREEHM 526 +K+ L +KI+ IS+ VGY + Y+ + FKK VG+SPS+YRE+ + Sbjct: 471 SKQFLSDPRYKIADISSKVGYSDGNYYSKTFKKIVGLSPSEYREKML 517 >B1DHI6.1 B1DHI6_9BACL Two component transcriptional regulator, AraC family Length = 539 Score = 151 bits (382), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 144/558 (25%), Positives = 265/558 (47%), Gaps = 68/558 (12%) Query: 13 KLFIADDEQLVVETLSEMIDWDAFGVRIIGTANNGKQALERILQSDPDIVLTDIRMPGLN 72 + I DDE ++ E ++ RI G A+NG+ AL + D+V+TDI+MPG+N Sbjct: 2 NILIVDDEPMIREWFQMTVERTGGDYRIAGEASNGEDALTFCRANPVDLVVTDIKMPGMN 61 Query: 73 GLDLIRTLKENGRKAECIIVSGYSEFEYAKEAIELEAVDYLIKP----AELDEVARTVSR 128 G+DLI+ LKE ++ S YSEF++A EA++ A +Y++K A L+E+ + + + Sbjct: 62 GIDLIKALKEEMPHIRSVVFSSYSEFQFAAEALKFGASEYILKAEITLAGLEEILQKIKK 121 Query: 129 AIQRLGRKADQTGNHPELRIAKA---LDRAVFTDLIVHGKRPS------FDQTPYGQYDQ 179 I L ++A N + ++ L A F +L+ G+ + ++ G ++ Sbjct: 122 DID-LDQRAASEINALRYSLNESQITLRNAYFRELLEGGREAANGFAERLERLHIGLSEK 180 Query: 180 -FAVILIG---SPATLLLERMKDKG-IADALLSFLANR-----GIVVDLLYEQQKVILLC 229 A++++G P L R++++G + +A+++ L G LY+ I+LC Sbjct: 181 HLALLVVGIVQGPEPL---RIREEGLLQNAVINILDETLHHELGNGCSFLYKPNLYIMLC 237 Query: 230 MANLKEDAPLTETLIAAAATFSNDGSWDDTLMSFAIGPVVTEIMHMH--VSYLA-----A 282 + E+L+ A+ S + L F V I HM+ +SYL A Sbjct: 238 NSVHTGLKSQRESLLVLASRAS------EHLQRFVGANAVIGISHMYSRLSYLPEQLSEA 291 Query: 283 YKACQMGLFFGAPVMDASSWTE-----ITRISERIVSDWSNQIQSFIRYEQKEFEAMLER 337 A LF+G P + +W E + S W++ Q ++ + R Sbjct: 292 LAAADRHLFYGDPGI---AWYEDNGSAASASYNSTGSGWTSAFQGYLE------NGLTAR 342 Query: 338 WTEWGTKQLIAPDTLKKTGAQWANRLHDLIGQDY-GIKIERVTGDRTRLIEEIH-----E 391 + K + +T ++ A+ A L L+ Y + R G T +E ++ E Sbjct: 343 AGSFLEKIMDEMETERQLSAKQARSL--LLELIYIAVNRGRTVGVPTEQLENLYIDAHVE 400 Query: 392 APDWASLKKICVDLAQSVQFYLNVTKTTLKE----KVVHEIKAYLESHYHENIQLDQLAE 447 +A+ +++ A+SV F+ + + + + + V Y+ HY E++ L +A+ Sbjct: 401 VQRYATFRELS-GWARSV-FHQIMDRISARRPQYGEAVERACEYITLHYAEDLMLQDIAD 458 Query: 448 RFDLNASYVSNLYSKSTGQTILEYVTLLRIRQAKKMLRGSSFKISKISTNVGYDNQRYFC 507 L+ +Y+S L+ K TG EY+ +R+ +AK++L+ + K++ + VGY N YF Sbjct: 459 HVHLSRTYISELFKKETGMNYNEYLMQVRMEKAKELLKRQTLKVADAAALVGYSNTSYFI 518 Query: 508 QVFKKHVGVSPSQYREEH 525 ++FK + G+SPS+Y E+ Sbjct: 519 KLFKNYTGLSPSEYMEQQ 536 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,122,425,555 Number of extensions: 127749872 Number of successful extensions: 440363 Number of sequences better than 1.0e-05: 15265 Number of HSP's gapped: 451923 Number of HSP's successfully gapped: 15998 Length of query: 537 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 396 Effective length of database: 1,732,333,088 Effective search space: 686003902848 Effective search space used: 686003902848 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)