BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0598.0023.p (312 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B9MNC7.1 B9MNC7_ANATD Xylose isomerase domain protein TIM barrel 154 1e-35 A4XGF6.1 A4XGF6_CALS8 Xylose isomerase domain protein TIM barrel 150 2e-34 A8S4D5.1 A8S4D5_9CLOT Putative uncharacterized protein 143 2e-32 B8FY76.1 B8FY76_DESHD Xylose isomerase domain protein TIM barrel 142 5e-32 C0CYI5.1 C0CYI5_9CLOT Putative uncharacterized protein 138 8e-31 >B9MNC7.1 B9MNC7_ANATD Xylose isomerase domain protein TIM barrel Length = 303 Score = 154 bits (389), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 86/294 (29%), Positives = 147/294 (50%), Gaps = 1/294 (0%) Query: 5 REQLEISLVHPGLWPAAATDEQVWERSVRLVLEDSFFGRIEVAPIANPQRRRRFAEWLRV 64 ++ +I +H +P E E +++++LED +F +E+ + +P+ R+R + L+ Sbjct: 6 KKYFKIGTIHFMSFPEVIGGEGPIEETLKIILEDDYFDAVEITWVKDPEVRKRVTKMLKD 65 Query: 65 TNMKASYLLQPLIFGQGYNLQSADQAERELAIKALIAAMDDALESGADRVTVISGPEDPQ 124 ++ +Y QP + G N D +R+ I L +D+A+E GA + +S D Sbjct: 66 AHIAVAYGAQPTLLRTGQNPNDLDPEKRKQVINFLKERIDEAIELGAQGLGFLSRQYDEA 125 Query: 125 AXXXXXXXXXXXXXXXXXXAAAERKLKLDLELFDTAVDKKRLFGDSRMADKLMQQLAGRT 184 A ++ ++LE+FD +DKK L G + +A K +++ Sbjct: 126 KKEEAFEALVDTTLQLCDYAKSKGNFLIELEVFDFDIDKKSLIGPAELAAKFAERIKKEY 185 Query: 185 THLALLADLSHVPLLGETIEDTVSNTQAWLGHVHIGNCCT-NPEDERYGDKHPYFGYPGG 243 + L+ DLSH+PL ET + + + +L HVHIGN +P YGDKHP FG GG Sbjct: 186 DNFGLIVDLSHLPLTRETAQQALLPVKDYLTHVHIGNAVVKDPSHPAYGDKHPMFGIEGG 245 Query: 244 CHDVPEVARFLQALISAGYLSSDRIAGLGIEIITAVDEDPGLLIAGAKRTLLKA 297 +DV EV FL+ L G++ + L E+ +DP +++A +KR L +A Sbjct: 246 ENDVDEVVEFLKVLKEIGFMDPIKRPILSFEVTPMAGQDPKIVLASSKRVLNEA 299 >A4XGF6.1 A4XGF6_CALS8 Xylose isomerase domain protein TIM barrel Length = 303 Score = 150 bits (378), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 89/291 (30%), Positives = 145/291 (49%), Gaps = 1/291 (0%) Query: 8 LEISLVHPGLWPAAATDEQVWERSVRLVLEDSFFGRIEVAPIANPQRRRRFAEWLRVTNM 67 L+I +H +P E E +++ +LED +F +E+ I + + RRR + L+ ++ Sbjct: 9 LKIGTIHFMSYPQVIDGEGPIEETLKSILEDDYFNAVEITWIKDNEVRRRVKDMLKSAHI 68 Query: 68 KASYLLQPLIFGQGYNLQSADQAERELAIKALIAAMDDALESGADRVTVISGPEDPQAXX 127 +Y QP + G N D +R AI+ L +D+A E GA +S D Sbjct: 69 TVAYGGQPRLLRTGLNPNDYDSEKRRKAIEILKEGIDEAYELGAVGFGFLSRQYDEARKE 128 Query: 128 XXXXXXXXXXXXXXXXAAAERKLKLDLELFDTAVDKKRLFGDSRMADKLMQQLAGRTTHL 187 A ++ L ++LE+FD +DKK L G + +A + ++ + Sbjct: 129 EAFKILVDTTKELCEYAKSKGNLMVELEVFDFDIDKKSLIGPAELAARFAAEIRKEYDNF 188 Query: 188 ALLADLSHVPLLGETIEDTVSNTQAWLGHVHIGNCCTNPEDE-RYGDKHPYFGYPGGCHD 246 L+ DLSH+PL ET + + + +L HVHIGN ++ YGDKHP FG GG +D Sbjct: 189 GLIVDLSHLPLTRETAQQALLPVKDYLTHVHIGNAVVKDKNHPAYGDKHPMFGIEGGEND 248 Query: 247 VPEVARFLQALISAGYLSSDRIAGLGIEIITAVDEDPGLLIAGAKRTLLKA 297 V EV FL+ L G+L+ ++ L E+ +DP +++A +KR L +A Sbjct: 249 VEEVIEFLRVLKEIGFLNPEKRPILSFEVSPMPGQDPKIVLASSKRVLNEA 299 >A8S4D5.1 A8S4D5_9CLOT Putative uncharacterized protein Length = 303 Score = 143 bits (361), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 84/300 (28%), Positives = 147/300 (49%), Gaps = 1/300 (0%) Query: 3 NWREQLEISLVHPGLWPAAATDEQVWERSVRLVLEDSFFGRIEVAPIANPQRRRRFAEWL 62 + R +++ ++ +P E + + D +F +EVA + + Q R++ AE + Sbjct: 4 SMRRFMKVGIILHVSYPQLGGGEGPILECLERICGDDYFEAVEVARMKDGQVRKKAAEMI 63 Query: 63 RVTNMKASYLLQPLIFGQGYNLQSADQAERELAIKALIAAMDDALESGADRVTVISGPED 122 R +M ++Y Q G N+ D+ R +A+ L +D+A E G + + G D Sbjct: 64 RAAHMVSAYGGQSRTLSAGLNINDLDETRRAMAVDTLKEGIDEAYEMGCAGFSFLCGRYD 123 Query: 123 PQAXXXXXXXXXXXXXXXXXXAAAERKLKLDLELFDTAVDKKRLFGDSRMADKLMQQLAG 182 A + + + E+FD +DK+ L G + +A + ++ Sbjct: 124 EGRKEQAFEQLLKSTRQLCGYAGEKGNMPICCEVFDYDIDKRALIGPAALAARYAGEIRR 183 Query: 183 RTTHLALLADLSHVPLLGETIEDTVSNTQAWLGHVHIGNCC-TNPEDERYGDKHPYFGYP 241 + LL DLSH+P+L ETIE+++ + ++ H H+GN +P+ E YGD HP FG+P Sbjct: 184 DYGNFGLLVDLSHIPMLHETIEESILPVKDYIIHAHMGNTVIKSPDCEAYGDNHPRFGFP 243 Query: 242 GGCHDVPEVARFLQALISAGYLSSDRIAGLGIEIITAVDEDPGLLIAGAKRTLLKALQAV 301 +DV E+A +L+ L+ G+L + + E+ DE P ++IA AKRTL A + V Sbjct: 244 DSENDVEELAHYLRTLMEIGFLGEKKRPIVSFEVKPWKDESPEVIIANAKRTLNLAWELV 303 >B8FY76.1 B8FY76_DESHD Xylose isomerase domain protein TIM barrel Length = 303 Score = 142 bits (357), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 80/293 (27%), Positives = 149/293 (50%), Gaps = 1/293 (0%) Query: 3 NWREQLEISLVHPGLWPAAATDEQVWERSVRLVLEDSFFGRIEVAPIANPQRRRRFAEWL 62 ++R+ +++ LVH +P+ + E ++R + D +F +E+ I +P R++ + + Sbjct: 4 SFRKYMKVGLVHFMAYPSTSKGEGPILETLRRIAMDEYFEVVEMTWIKDPAVRKKARQII 63 Query: 63 RVTNMKASYLLQPLIFGQGYNLQSADQAERELAIKALIAAMDDALESGADRVTVISGPED 122 ++M+ SY P + N+ S ++ ER A+ + +D+A E GA +SG + Sbjct: 64 ETSHMEFSYAGMPRLLPTKQNINSLNEEERLQALANVKEGIDEAYEMGAKDFAFLSGKYE 123 Query: 123 PQAXXXXXXXXXXXXXXXXXXAAAERKLKLDLELFDTAVDKKRLFGDSRMADKLMQQLAG 182 A ++ +K+ +E+FD VDK L G + + +++ Sbjct: 124 EPRKEEAYQALIRSTKEICAYAKSKGDMKIAIEVFDYDVDKCSLIGPVALTQRYAKEIRR 183 Query: 183 RTTHLALLADLSHVPLLGETIEDTVSNTQAWLGHVHIGNCCTNPE-DERYGDKHPYFGYP 241 + L+ DLSH+P L ET +++ + ++ H H+GN + YGD+HP FG+P Sbjct: 184 EYDNFGLMVDLSHLPQLRETPAESLIPVKDYIIHAHMGNTLVKDKLSPVYGDEHPRFGFP 243 Query: 242 GGCHDVPEVARFLQALISAGYLSSDRIAGLGIEIITAVDEDPGLLIAGAKRTL 294 G +DV E+ +L+ L+ G+L+ + + +E+ DEDP L+IA AKR L Sbjct: 244 GSENDVAELVEYLRVLLDIGFLNKENRPIVSLEVKPYEDEDPELVIANAKRVL 296 >C0CYI5.1 C0CYI5_9CLOT Putative uncharacterized protein Length = 298 Score = 138 bits (347), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 82/280 (29%), Positives = 134/280 (47%), Gaps = 1/280 (0%) Query: 18 WPAAATDEQVWERSVRLVLEDSFFGRIEVAPIANPQRRRRFAEWLRVTNMKASYLLQPLI 77 W + TD +VR + D +E+ +P+ +++ L +++ +Y QP+I Sbjct: 16 WMSFPTDRYDPVDAVRHIARDGDLDAVEITDYKDPEVKKQIRHILNQSHLSVAYGAQPVI 75 Query: 78 FGQGYNLQSADQAERELAIKALIAAMDDALESGADRVTVISGPEDPQAXXXXXXXXXXXX 137 G+ N S D+ ER +A + L+ AM+DA GA + ++G + Sbjct: 76 LGENLNPNSLDEPERRMAQERLLEAMEDAKSFGASGFSFMAGAWCREGKEEALSQLKKTA 135 Query: 138 XXXXXXAAAERKLKLDLELFDTAVDKKRLFGDSRMADKLMQQLAGRTTHLALLADLSHVP 197 ++ + ++LE+FD +DKK L G + +A + ++ T + LLADLSH P Sbjct: 136 RALCSRGSS-LGMAVELEVFDFDLDKKVLIGPAPLAARFASEMRQVTNNFGLLADLSHFP 194 Query: 198 LLGETIEDTVSNTQAWLGHVHIGNCCTNPEDERYGDKHPYFGYPGGCHDVPEVARFLQAL 257 E V + +L H HIGN PE + YGDKHP FGYP G +DV E+ F L Sbjct: 195 TTYEDSAFAVRAMRPYLTHFHIGNAVVTPEKDAYGDKHPRFGYPHGANDVGELYDFFTVL 254 Query: 258 ISAGYLSSDRIAGLGIEIITAVDEDPGLLIAGAKRTLLKA 297 G+ +S L E+ E+ +++A KR + +A Sbjct: 255 RQEGFFNSRNPVMLSAEVTPRPGEEAEIVLANTKRVINRA 294 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,771,631,425 Number of extensions: 68569345 Number of successful extensions: 146918 Number of sequences better than 1.0e-05: 14 Number of HSP's gapped: 146899 Number of HSP's successfully gapped: 14 Length of query: 312 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 177 Effective length of database: 1,788,859,178 Effective search space: 316628074506 Effective search space used: 316628074506 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 131 (55.1 bits)