BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0598.0010.p
         (127 letters)

Database: pfamseq 
           9,421,015 sequences; 3,060,696,203 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

B3KF95.1 B3KF95_9BACI Bifunctional deaminase-reductase domain pr...   239   6e-62
B2I225.1 B2I225_ACIBC Dihydrofolate reductase                         214   1e-54
A3M5R3.2 A3M5R3_ACIBT Putative dihydrofolate reductase                213   3e-54
Q4A0X3.1 Q4A0X3_STAS1 Putative dihydrofolate reductase                176   5e-43
C1U6X5.1 C1U6X5_9SPHI Dihydrofolate reductase                         139   9e-32

>B3KF95.1 B3KF95_9BACI Bifunctional deaminase-reductase domain protein
          Length = 191

 Score =  239 bits (610), Expect = 6e-62,   Method: Compositional matrix adjust.
 Identities = 117/127 (92%), Positives = 121/127 (95%)

Query: 1   VLSNPSASQHERNHAEWIEKTAKIVFSTTLENVEWNNSRLVKEGVEEEINNLKQQPGEDM 60
           V SNPSASQHE NHAEWIEKTAKI+FSTTLE VEWNNSRLVKE VEEEI NLKQQPG+DM
Sbjct: 65  VPSNPSASQHELNHAEWIEKTAKIIFSTTLEKVEWNNSRLVKEDVEEEIKNLKQQPGKDM 124

Query: 61  VILGSPRFAHHLMQLDLIDEYKITVSPVLIGKGLPLFQGLKEKINLKLIENKTFDSGAIG 120
           VILGSPRFAH+LMQLDLIDEYKITVSPVLIG GLPLFQGLKEK+NLKLIENKTFDSGAIG
Sbjct: 125 VILGSPRFAHYLMQLDLIDEYKITVSPVLIGSGLPLFQGLKEKVNLKLIENKTFDSGAIG 184

Query: 121 LVYQTVR 127
           LVYQTVR
Sbjct: 185 LVYQTVR 191


>B2I225.1 B2I225_ACIBC Dihydrofolate reductase
          Length = 191

 Score =  214 bits (546), Expect = 1e-54,   Method: Compositional matrix adjust.
 Identities = 103/126 (81%), Positives = 115/126 (91%)

Query: 1   VLSNPSASQHERNHAEWIEKTAKIVFSTTLENVEWNNSRLVKEGVEEEINNLKQQPGEDM 60
           +LSNP AS+HERNHAEWIEKT KIVFSTTL+ VEWNNSRLVK+ VEEEIN LKQQPG+DM
Sbjct: 65  MLSNPEASEHERNHAEWIEKTEKIVFSTTLDTVEWNNSRLVKDHVEEEINKLKQQPGKDM 124

Query: 61  VILGSPRFAHHLMQLDLIDEYKITVSPVLIGKGLPLFQGLKEKINLKLIENKTFDSGAIG 120
           VILGSPRFAH+LMQL LIDEYKITVSPVL+G GLPLFQG+++K +LKLIENKTF SGAIG
Sbjct: 125 VILGSPRFAHYLMQLGLIDEYKITVSPVLLGSGLPLFQGIEQKTSLKLIENKTFASGAIG 184

Query: 121 LVYQTV 126
           L YQ +
Sbjct: 185 LHYQKI 190


>A3M5R3.2 A3M5R3_ACIBT Putative dihydrofolate reductase
          Length = 191

 Score =  213 bits (543), Expect = 3e-54,   Method: Compositional matrix adjust.
 Identities = 103/126 (81%), Positives = 114/126 (90%)

Query: 1   VLSNPSASQHERNHAEWIEKTAKIVFSTTLENVEWNNSRLVKEGVEEEINNLKQQPGEDM 60
           +LSNP AS+HERNHAEWIEKT K+VFSTTL+ VEWNNSRLVK+ VEEEIN LKQ+ G+DM
Sbjct: 65  MLSNPEASEHERNHAEWIEKTEKVVFSTTLDTVEWNNSRLVKDHVEEEINRLKQKQGKDM 124

Query: 61  VILGSPRFAHHLMQLDLIDEYKITVSPVLIGKGLPLFQGLKEKINLKLIENKTFDSGAIG 120
           VILGSPRFAH+LMQL LIDEYKITVSPVLIG GLPLFQG++EK NLKLIENKTF SGAIG
Sbjct: 125 VILGSPRFAHYLMQLGLIDEYKITVSPVLIGSGLPLFQGIQEKTNLKLIENKTFASGAIG 184

Query: 121 LVYQTV 126
           L YQ +
Sbjct: 185 LHYQKI 190


>Q4A0X3.1 Q4A0X3_STAS1 Putative dihydrofolate reductase
          Length = 192

 Score =  176 bits (446), Expect = 5e-43,   Method: Compositional matrix adjust.
 Identities = 82/126 (65%), Positives = 108/126 (85%)

Query: 1   VLSNPSASQHERNHAEWIEKTAKIVFSTTLENVEWNNSRLVKEGVEEEINNLKQQPGEDM 60
           V S+ +A++HE NHA+WIE   K+VFS  L +VEW+NS+LVK+ VEEEIN LKQQ G D+
Sbjct: 66  VPSDENANEHELNHAQWIENVEKVVFSKALNHVEWSNSKLVKDHVEEEINKLKQQEGGDI 125

Query: 61  VILGSPRFAHHLMQLDLIDEYKITVSPVLIGKGLPLFQGLKEKINLKLIENKTFDSGAIG 120
           V+LGSPRFAH+LMQL+L+DEYKIT+SP LIGKGLPLFQ + +K++LKLI+++TF+SGA+G
Sbjct: 126 VVLGSPRFAHYLMQLNLVDEYKITISPTLIGKGLPLFQNIHDKVDLKLIKSETFESGALG 185

Query: 121 LVYQTV 126
           L YQ +
Sbjct: 186 LNYQVL 191


>C1U6X5.1 C1U6X5_9SPHI Dihydrofolate reductase
          Length = 188

 Score =  139 bits (350), Expect = 9e-32,   Method: Compositional matrix adjust.
 Identities = 65/123 (52%), Positives = 87/123 (70%)

Query: 1   VLSNPSASQHERNHAEWIEKTAKIVFSTTLENVEWNNSRLVKEGVEEEINNLKQQPGEDM 60
           VL+NP A++H   HA W+ +  K VFSTTL + +WNN+ L+K+ V EEI+ LKQQPG+D+
Sbjct: 63  VLNNPEANEHALKHARWVHEIPKFVFSTTLPSADWNNTTLIKDNVAEEISKLKQQPGKDL 122

Query: 61  VILGSPRFAHHLMQLDLIDEYKITVSPVLIGKGLPLFQGLKEKINLKLIENKTFDSGAIG 120
           VI GSP  A  LM L LIDEYK+T+ P+++GKG+ LF    E   LKL+E+KT  SG + 
Sbjct: 123 VIFGSPGLAKSLMNLGLIDEYKLTLHPIILGKGISLFDSNTEMSKLKLVESKTLGSGVVT 182

Query: 121 LVY 123
           L Y
Sbjct: 183 LHY 185


  Database: pfamseq
    Posted date:  Aug 5, 2010  3:22 PM
  Number of letters in database: 3,060,696,203
  Number of sequences in database:  9,421,015
  
Lambda     K      H
   0.315    0.134    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 9421015
Number of Hits to DB: 786,213,048
Number of extensions: 31248165
Number of successful extensions: 60435
Number of sequences better than 1.0e-05: 388
Number of HSP's gapped: 60398
Number of HSP's successfully gapped: 388
Length of query: 127
Length of database: 3,060,696,203
Length adjustment: 92
Effective length of query: 35
Effective length of database: 2,193,962,823
Effective search space: 76788698805
Effective search space used: 76788698805
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 126 (53.1 bits)