BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0598.0005.p (622 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A7VQN6.1 A7VQN6_9CLOT Putative uncharacterized protein 391 e-106 C5ETL1.1 C5ETL1_9FIRM Histidine kinase internal region 373 e-101 A7VQM9.1 A7VQM9_9CLOT Putative uncharacterized protein 370 e-100 A6LXG3.1 A6LXG3_CLOB8 Histidine kinase internal region 345 9e-93 C5EQZ0.1 C5EQZ0_9FIRM Putative uncharacterized protein 299 5e-79 >A7VQN6.1 A7VQN6_9CLOT Putative uncharacterized protein Length = 571 Score = 391 bits (1004), Expect = e-106, Method: Compositional matrix adjust. Identities = 222/584 (38%), Positives = 350/584 (59%), Gaps = 31/584 (5%) Query: 43 YTSTARSMQHKINELLEGNLIQAARSVDREIASYNDLLYQIFTDEDITQLTLKMTHGSDN 102 Y +T +Q +EL E NL+Q +SV +A+Y DLL+Q++T +DI ++ G + Sbjct: 3 YYNTTGIVQENTDELAEVNLVQTDKSVRSTLAAYEDLLFQLYTGDDIVNDVDELNAGGN- 61 Query: 103 EQIISFGKLREKLGVLANSKDGISNISILMPNDLVVCYDKITGLATQHYWAKFGGXXXXD 162 + ++ +LR L +AN KD I I+I+ + ++ YDK T + ++ W Sbjct: 62 -EALAVNQLRRTLRGIANIKDSIQCITIITESGDIIFYDKPTASSIKNSW--LDTMNLTP 118 Query: 163 TEFYKQAGQTDQTVILPTEYADQYGEKSTHLFHLAKRMFD---IGRQNKNTIGVIVISLK 219 E Y + + T + T YA + K +LFHLA R+ D I RQ +GVI+IS+ Sbjct: 119 EELYDKISNENSTQYITTRYASSFSAKPYYLFHLAHRIVDYNSIHRQ----LGVIIISID 174 Query: 220 EEVLSEAVNYANMHLNGS---GFNYIVDHNQTIISFP-----EKTLIGEPET-NFLNQHA 270 E +L E N ++ + + N+IVD +++FP E T++ PE+ N + Sbjct: 175 ERLLHEVCNQNSVDGDDTLPGNVNFIVDDEGRLVTFPVQRSIENTVLPIPESENGWRESY 234 Query: 271 IKLTSGSTVSSVWAERWNKKPVLVNKQTDSTLGWSFVNITDKKEMFREMQSHQRLYLMIG 330 +L GS + + ++ D LGWSFVN++D+ +FR++++ + L L+ Sbjct: 235 GELIEGSGL-------MDGDNFAIHSLRDDLLGWSFVNVSDQSVVFRQIEAQRNLMLLAV 287 Query: 331 VLTIVFSLLLAVYFSGKFTHSLRTIVRAMTSAKRGNLDVQL--NFHTEDEIAIISSSFNS 388 L++ F + + + + T S++ IV AM A G+L V++ + E+ I+ FN Sbjct: 288 FLSVAFLIAVIILVTRHMTGSIKNIVAAMKKAGAGDLAVRVRRDRKMPSEMETITDQFNR 347 Query: 389 MIGQIKELVEDVKSAARQQKDAEIKALEAQINPHFLYNTLDTINWIAIENEQYKISHMLK 448 M+GQ+ +LVE+VK + +QKDAEI ALEAQINPHFLYNTLDTINW+AI +QY+IS + Sbjct: 348 MMGQMNKLVEEVKMVSARQKDAEITALEAQINPHFLYNTLDTINWMAINADQYEISSAIG 407 Query: 449 NLAQILRYTISPSNEIVPIRKEMEWLRQYIYLQQIRFEHSFECVLEVEEAVVDCKIYKLL 508 LA+ILRY I SN IV +R+EMEWL+QYI+LQQ R +++F L+V + ++DCKI+KLL Sbjct: 408 ALARILRYGIDKSNSIVTLREEMEWLQQYIFLQQTRLKNTFSYELDVPKELLDCKIHKLL 467 Query: 509 LQPFIENAILHGLEGCRTGGLITVTVGGYKSSCIQVRITDNGRGMTPEQLAQILNRKEQT 568 QPF+ENAILHG EG R ++ V V ++ +Q+ + DNG+G+ ++ +I +R + Sbjct: 468 FQPFVENAILHGFEGVRRHHILVVKVQKRQNGFLQIIVKDNGKGIQENKIQEIKSRLLDS 527 Query: 569 VKKKGGGLGIHNVFTRLRLYYGQDCRWNITSQLGEGTQVLLEIP 612 +K +G++N RLR+YYG++ R++I SQ+GEGT V++EIP Sbjct: 528 GEKD--HIGMNNAIERLRMYYGEEARFDIKSQVGEGTVVIIEIP 569 >C5ETL1.1 C5ETL1_9FIRM Histidine kinase internal region Length = 571 Score = 373 bits (957), Expect = e-101, Method: Compositional matrix adjust. Identities = 209/579 (36%), Positives = 328/579 (56%), Gaps = 15/579 (2%) Query: 36 MVVQFIVYTSTARSMQHKINELLEGNLIQAARSVDREIASYNDLLYQIFTDEDITQLTLK 95 M +QFI Y A S++ KI+ L+ NL Q + VD + Y++L+YQI+ D+ I + Sbjct: 1 MTIQFIGYNMNANSLKRKIDTLMVDNLTQLSERVDLTMDIYSNLVYQIYVDDKIIENVNI 60 Query: 96 MTHGSDNEQIISFGKLREKLGVLANSKDGISNISILMPNDLVVCYDKITGLATQHYWAKF 155 + G+ + ++F + +L S GI +IS++ N V YD TG + ++ W + Sbjct: 61 LLDGNGEGREVAFHSIYNRLQQAEKSVKGIRSISVICANGQSVTYDAGTGSSIENLWDDY 120 Query: 156 GGXXXXDTEFYKQAGQTDQTVILPTEYADQYGEKSTHLFHLAKRMFDIGRQNKNTIGVIV 215 + E Y+ ++ PT Y + + FH++K M+D ++ TI IV Sbjct: 121 --RDLREIEPYQAVQGLPGMLVTPTTRHKGY-DGDAYYFHISKCMYDYNNLDRGTIATIV 177 Query: 216 ISLKEEVLSEAVNYANMHLNGS-GFNYIVDHNQTIISFPEKTLIGEPETNFLNQHAIKLT 274 +S+ E VL + A N+I D + +IS+P G +N + +LT Sbjct: 178 MSVDEGVLRDICAVAIAEDEAEYNINFITDTDGFVISYPNPFYTG------INMNP-RLT 230 Query: 275 SGSTVSSVWAERWNKKPVLVNKQTDSTLGWSFVNITDKKEMFREMQSHQRLYLMIGVLTI 334 V + + VNK + GW + N+ +K M R+++++Q ++++I + I Sbjct: 231 VQEFVQVTGLLK--GQNTAVNKYVNQNRGWVYYNVYNKDYMMRDIRNNQIMFILISLAAI 288 Query: 335 VFSLLLAVYFSGKFTHSLRTIVRAMTSAKRGNLDVQLNFHTEDEIAIISSSFNSMIGQIK 394 +FS +L Y + S+ I + K GNL+V + + DE+ I+S+FN M G+++ Sbjct: 289 LFSSILISYIVRRIGSSVALITDGIDQVKEGNLNVSVALESRDELGQIASNFNDMTGKVR 348 Query: 395 ELVEDVKSAARQQKDAEIKALEAQINPHFLYNTLDTINWIAIENEQYKISHMLKNLAQIL 454 LV +V A +QK+AEI+ALEAQINPHFLYNTLD+INW+AIE E+Y+IS ML+NL IL Sbjct: 349 NLVAEVSEAKDKQKNAEIRALEAQINPHFLYNTLDSINWMAIEKEEYEISRMLRNLGVIL 408 Query: 455 RYTISPSNEIVPIRKEMEWLRQYIYLQQIRFEHSFECVLEVEEAVVDCKIYKLLLQPFIE 514 RY+++ SN++V + + +WL +YI LQQ+RF SF L V EA +IYKLLLQPF+E Sbjct: 409 RYSVNRSNQMVSVTEVADWLEKYISLQQMRFNQSFRFELNVAEAAGKVRIYKLLLQPFVE 468 Query: 515 NAILHGLEGCRTGGLITVTVG-GYKSSCIQVRITDNGRGMTPEQLAQILNRKEQTVKKKG 573 NAI+HG + GG++ V + + + I DNG+GM P +A+ N +EQ VK +G Sbjct: 469 NAIIHGFKDTEKGGVLRVDIFLSETGERLNIIIEDNGKGM-PRDMAESFNVREQAVKDEG 527 Query: 574 GGLGIHNVFTRLRLYYGQDCRWNITSQLGEGTQVLLEIP 612 G +G+HN F R+ +YYG++ WN+ S G GT V L +P Sbjct: 528 GSIGLHNAFARMDMYYGREAVWNVNSIEGMGTVVTLTLP 566 >A7VQM9.1 A7VQM9_9CLOT Putative uncharacterized protein Length = 576 Score = 370 bits (951), Expect = e-100, Method: Compositional matrix adjust. Identities = 214/589 (36%), Positives = 340/589 (57%), Gaps = 36/589 (6%) Query: 43 YTSTARSMQHKINELLEGNLIQAARSVDREIASYNDLLYQIFTDEDITQLTLKMTHGSDN 102 Y +T +Q +EL E NL+Q +SV +A+Y DLL+Q++T +DI ++ G + Sbjct: 3 YYNTTGIVQENTDELAEVNLVQTDKSVRSTLAAYEDLLFQLYTGDDIVNDVDELNAGGN- 61 Query: 103 EQIISFGKLREKLGVLANSKDGISNISILMPNDLVVCYDKITGLATQHYWAKFGGXXXXD 162 + ++ +LR L +AN KD I I+I+ + ++ YDK T + ++ W Sbjct: 62 -EALAVNQLRRTLRGIANIKDSIQCITIITESGDIIFYDKPTASSIKNSW--LDTMNLTP 118 Query: 163 TEFYKQAGQTDQTVILPTEYADQYGEKSTHLFHLAKRMFD---IGRQNKNTIGVIVISLK 219 E Y + + T + T YA + K +LFHLA R+ D I RQ +GVI+IS+ Sbjct: 119 EELYDKISNENSTQYITTRYASSFSAKPYYLFHLAHRIVDYNSIHRQ----LGVIIISID 174 Query: 220 EEVLSEAVNYANMHLNGS---GFNYIVDHNQTIISFP-----EKTLIGEPET-NFLNQHA 270 E +L E N ++ + + N+IVD +++FP E T++ PE+ N + Sbjct: 175 ERLLHEVCNQNSVDGDDTLPGNVNFIVDDEGRLVTFPVQRSIENTVLPIPESENGWRESY 234 Query: 271 IKLTSGSTVSSVWAERWNKKPVLVNKQTDSTLGWSFVNITDKKEMFREMQSHQRLYLMIG 330 +L GS + + ++ D LGWSFVN++D+ +FR++++ + L L+ Sbjct: 235 GELIEGSGL-------MDGDNFAIHSLRDDLLGWSFVNVSDQSVVFRQIEAQRNLMLLAV 287 Query: 331 VLTIVFSLLLAVYFSGKFTHSLRTIVRAMTSAKRGNLDVQL--NFHTEDEIAIISSSFNS 388 L++ F + + + + T S++ IV AM A G+L V++ + E+ I+ FN Sbjct: 288 FLSVAFLIAVIILVTRHMTGSIKNIVAAMKKAGAGDLAVRVRRDRKMPSEMETITDQFNR 347 Query: 389 MIGQIKELVEDVKSAARQQKDAEIKALEAQINPHFLYNTLDTINWIAIENEQYKISHMLK 448 M+GQ+ +LVE+VK + +QKDAEI ALEAQINPHFLYNTLDTINW+AI +QY+IS + Sbjct: 348 MMGQMNKLVEEVKMVSARQKDAEITALEAQINPHFLYNTLDTINWMAINADQYEISSAIG 407 Query: 449 NLAQILRYTISPSNEIVPIRKEMEWLRQYIYLQQIRFEHSFECVLEVEEAVVDCKIYKLL 508 LA+ILRY I SN IV +R+EMEWL+QYI+LQQ R +++F C + V ++DC I+KL+ Sbjct: 408 ALARILRYGIDKSNSIVTLREEMEWLQQYIFLQQTRLKNTFSCQIIVPPELLDCLIHKLI 467 Query: 509 LQPFIENAILHGLEGCRTGGLITVTVGGYKSSCIQVRITDNGRGMTPEQLAQILNRKEQT 568 QPF+ENAILHG EG + ++ + + + + I DNG+G+ ++ +I +Q Sbjct: 468 FQPFVENAILHGFEGVQQHHILIIEIQEKPKELLNITIHDNGKGIEAAKVEEI----KQG 523 Query: 569 V---KKKGGGLGIHNVFTRLRLYYGQDCRWNITSQLGEGTQVLLEIPQC 614 + K LG+ N RL++YYG+D + I SQ G+GT +++ IP+ Sbjct: 524 ILPDNKSKNHLGMKNAIDRLKMYYGEDAEFIIESQEGKGTTIVIRIPKT 572 >A6LXG3.1 A6LXG3_CLOB8 Histidine kinase internal region Length = 627 Score = 345 bits (885), Expect = 9e-93, Method: Compositional matrix adjust. Identities = 202/629 (32%), Positives = 352/629 (55%), Gaps = 25/629 (3%) Query: 1 MNRMIGLIRGMFKGYKRSLKGKLILSFLFTAILPLMVVQFIVYTSTARSMQHKINELLEG 60 N IR F + S+K KL+ F+ +I+P+++ Q +Y + ++ KI L + Sbjct: 4 FNNRTNTIRYFFNWKRYSIKAKLLSIFIIISIIPMVLSQVFLYKLSQHYLEKKITNLTDR 63 Query: 61 NLIQAARSVDREIASYNDLLYQIFTDEDITQLTLKMTHGSDNEQIISFGKLREKLGVLAN 120 NL +++ ++ Y D+LY+I D D +L G++ E+ S K+R+ G + Sbjct: 64 NLFYIKTNIETDMNYYKDILYRIAADNDCLELEKMFNDGNEFEKAASINKIRDAFGSYSY 123 Query: 121 SKDGISNISILMPNDLVVCYDKITGLATQHYWAKFGGXXXXDTEFYKQAGQTDQTVILPT 180 S++ I I+ + N V YDK W ++ + Y + ++ VILPT Sbjct: 124 SRNQIRAITFVGNNGRNVYYDKGNQGINNRIWEEYSNSDK--SRIYSEILNSNTPVILPT 181 Query: 181 EYADQYGEKSTHLFHLAKRMFDIGRQNKNTIGVIVISLKEEVLSEAVNYANMHLNGSGF- 239 KS ++FH+ ++ DI + K+ IG+I++S E++L + N+ ++ F Sbjct: 182 TCNSFIHGKSEYMFHIGLKVRDI--RTKDEIGIIIMSFDEQILFDV---CNVQMDKEDFE 236 Query: 240 -------NYIVDHNQTIISFPEKTLIGEPETNFLNQHAIKLTSGSTVSSVWAE--RWNKK 290 + IVD++ +ISF +K IG ++ + + T++ + + + Sbjct: 237 EDKLNMCSVIVDNDGRVISFQDKKYIGTYVKDYSSSEINDTDNMETLNQLIYSIPTFKDR 296 Query: 291 PVLVNKQTDSTLGWSFVNITDKKEMFREMQSHQRLYLMIGVLTIVFSLLLAVYFSGKFTH 350 + V+ ++GW +N+ DK +F E++ + L + L ++ L+ + FS K Sbjct: 297 NISVSSILIDSVGWKVINVVDKDNLFYEVKLLRNLTFVFLGLILIILTLVIIIFSNKLYE 356 Query: 351 SLRTIVRAMTSAKRGNLDVQLNFHTEDEIAIISSSFNSMIGQIKELVEDVKSAAR----- 405 S++ IV M AK+GN +V++ TEDE++ I FN M+ I L+ D+K + Sbjct: 357 SVKIIVSGMKEAKKGNFNVKIKLSTEDEMSFIGDEFNEMLSTINILIRDIKDQSNFIVEL 416 Query: 406 --QQKDAEIKALEAQINPHFLYNTLDTINWIAIENEQYKISHMLKNLAQILRYTISPSNE 463 ++++AEIKA+ AQINPHFLYNTLD INW+AI+NE Y++S + N AQILRY+I N+ Sbjct: 417 SNKRREAEIKAIVAQINPHFLYNTLDCINWMAIKNENYEVSDTIGNFAQILRYSIGDINK 476 Query: 464 IVPIRKEMEWLRQYIYLQQIRFEHSFECVLEVEEAVVDCKIYKLLLQPFIENAILHGLEG 523 V I E+EWL++Y+YLQQ+RF +SF L+V+E V++ +I+KL+LQP IEN+I+HG +G Sbjct: 477 EVTIYDEVEWLKKYVYLQQLRFNNSFVLDLDVDENVLEARIHKLILQPLIENSIIHGFKG 536 Query: 524 CRTGGLITVTVGGYKSSCIQVRITDNGRGMTPEQLAQILNRKEQTVKKKGGGLGIHNVFT 583 + ++ V + +K++ +++ + DNG G+ +L +I+N + K + +GI NV+ Sbjct: 537 YDSERVLKVRINIFKNNYVKIIVKDNGLGIEDRKLQEIINNI-TSGKDEDENIGIKNVYD 595 Query: 584 RLRLYYGQDCRWNITSQLGEGTQVLLEIP 612 R+++YYG+D ++NI S G+GT + L I Sbjct: 596 RIKIYYGEDAKFNIESVKGQGTTITLIIS 624 >C5EQZ0.1 C5EQZ0_9FIRM Putative uncharacterized protein Length = 572 Score = 299 bits (766), Expect = 5e-79, Method: Compositional matrix adjust. Identities = 174/557 (31%), Positives = 291/557 (52%), Gaps = 27/557 (4%) Query: 64 QAARSVDREIASYNDLLYQIFTDEDITQLTLKMTHGSDNEQIISFGKLREKLGVLANSKD 123 QAA ++ + Y + + Q+ DE + E++ +LR+++ + + Sbjct: 35 QAASNIAATLNGYEEAVNQMTIDEKFLDYMQQFEEARGQEELGVKQELRKQMRTFMSYRP 94 Query: 124 GISNISILMPNDLVVCYDKITGLATQHYWAKFGGXXXXDTEFYK-QAGQTDQTVIL---- 178 + +++ N V D++ + E Y Q ++ IL Sbjct: 95 QVWCMAVETENGKVFSSDRL----------QIDSLYQKSPELYDLYFSQVEKQEILKGEW 144 Query: 179 -PTEYADQYGEKSTHLFHLAKRMFDIGRQNKNTIGVIVISLKEEVLSEAVNYANMHLN-G 236 P EY D+ G +LF KR+ D +G ++ + E VLS+ A + + Sbjct: 145 IPAEYYDRQGTSDYYLFTYRKRLMDF--YTARYVGTFLMGVNELVLSDICQEAQITPDRN 202 Query: 237 SGFNYIVDHNQTIISFPEKTLIGEPETNFLNQHAIKLTSGSTVSSVWAERWNKKPVLVNK 296 + +N+IVD + I+S +K+ IG ++ + + V V +K VLV+ Sbjct: 203 TNYNFIVDQDNRIVSHYDKSRIGMDISDMDGWEQLTMGGSQDVHLVKENHEDKTVVLVDI 262 Query: 297 QTDSTLGWSFVNITDKKEMFREMQSHQRLYLMIGVLTIVFSLLLAVYFSGKFTHSLRTIV 356 S W + D + +E+++ QR+ MI + +V S + + S++ +V Sbjct: 263 PKTS---WRLAGVLDNDYILKEIRNFQRIIWMITICLMVLGGFFIWILSRRLSASVKQVV 319 Query: 357 RAMTSAKRGNLDVQLNFHTEDEIAIISSSFNSMIGQIKELVEDVKSAARQQKDAEIKALE 416 M + G + + ++EI+II+S FN M+ QI ++++K + +KDAEI+ALE Sbjct: 320 NTMKEVRAGEMSAHMEMEGKNEISIIASQFNKMMKQINNQMDEIKQVSEMKKDAEIRALE 379 Query: 417 AQINPHFLYNTLDTINWIAIENEQYKISHMLKNLAQILRYTISPSNEIVPIRKEMEWLRQ 476 AQINPHF+YNTLD+I+W+AIEN + +IS ML AQILRY IS SN++V I++EME+L++ Sbjct: 380 AQINPHFIYNTLDSIHWLAIENGEDEISEMLSEFAQILRYQISGSNDVVKIKEEMEYLKK 439 Query: 477 YIYLQQIRFEHSFECVLEVEEAVVDCKIYKLLLQPFIENAILHGLEGCRTGGLITVTVGG 536 Y++LQ+IRF +FE ++ EE ++DC I+K++ QP IENAI+HG R GG + + + Sbjct: 440 YLFLQKIRFMDNFEYAIDCEEGILDCHIHKMIFQPLIENAIIHGYANIRHGGFLRIKIYH 499 Query: 537 YKSSCIQVRITDNGRGMTPEQLAQILNRKEQTVKKKGGGLGIHNVFTRLRLYYGQDCRWN 596 S I ITDNGRGM+PE++ ++ T +G+ NV RL+LYYG R Sbjct: 500 INESGICFSITDNGRGMSPEKVGEVFGEGGST-----PSIGVSNVLARLKLYYGDSYRME 554 Query: 597 ITSQLGEGTQVLLEIPQ 613 + S+ GT + + IP+ Sbjct: 555 VHSEENRGTSIKITIPK 571 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.136 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,493,333,394 Number of extensions: 141918279 Number of successful extensions: 425390 Number of sequences better than 1.0e-05: 2604 Number of HSP's gapped: 422833 Number of HSP's successfully gapped: 2604 Length of query: 622 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 480 Effective length of database: 1,722,912,073 Effective search space: 826997795040 Effective search space used: 826997795040 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)