BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0596.0027.p (516 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KDQ8.1 B3KDQ8_9BACI Response regulator receiver 343 3e-92 B1D7X3.1 B1D7X3_9BACL Two component transcriptional regulator, A... 293 3e-77 Q9KBL6.1 Q9KBL6_BACHD Two-component response regulator 267 2e-69 Q5WIY3.1 Q5WIY3_BACSK Two-component response regulator 238 9e-61 B9MLE2.1 B9MLE2_ANATD Two component transcriptional regulator, A... 214 2e-53 >B3KDQ8.1 B3KDQ8_9BACI Response regulator receiver Length = 518 Score = 343 bits (879), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 205/522 (39%), Positives = 303/522 (58%), Gaps = 17/522 (3%) Query: 1 MIKVVIVDDEPKLRQGLQTLIPWENLGFTVTAAAGNGRDALKIVEEEVPDLVIADIRMPV 60 M+KV+IVDDEPKLR+GL++++PW LG+ V A NG +AL+ + PDL++ DIRMP Sbjct: 1 MMKVLIVDDEPKLREGLKSIVPWTELGYQVVDTAANGNEALEKHGKYDPDLMLIDIRMPG 60 Query: 61 MDGLQFIQRLRSAGHQMHCIILSGYADFEYAKQAITYGVAGYLVKPVNIAEMSATLKLVX 120 MDGLQ I+ +R+ ++H +ILSGYADF+YAK+AI++ V GYL+KPV+ E+S L + Sbjct: 61 MDGLQLIEAIRNLDAEIHLLILSGYADFDYAKRAISHRVDGYLLKPVDEDELSKYLLQIK 120 Query: 121 XXXXXXXXXXXWYRTEV-TNRELYLRRLLAPQEKTEDPAKLRSRIREMDLLWSHYEIVVI 179 R +RE +++ P+ K D A LR LLW+HY++++ Sbjct: 121 EAIEQEQERKALNRAASEMSREQFIQTWFNPESKP-DSAALRHMAERSGLLWNHYQVLLF 179 Query: 180 SPRVPEADRPEHLHQLSAGLKHGIEGRNRGLVTVIAPYVILLLNSPL---HGRQRRDHLY 236 + E +L L E RG V + + +L+ +P+ GR+ L Sbjct: 180 HHNGSDESGEETDDRLKNQLIEAFEENGRGAVFSLHGQLGILMPTPVLTAGGRKELLQLV 239 Query: 237 GEIRSIAGDTRFIAATGGTVSEPELIYSAFLKAQEAVKQVFFSAKDCLLEPERTLFAAPE 296 E S AG T A+ G V E + ++ A+E +++ FF A +L PE FA Sbjct: 240 EEAASRAG-TAITASLGRQVHRLEDVADSYRCAKERIRERFFYAPGEMLFPESERFAG-- 296 Query: 297 FPREAGDRDEKRM----EDLIFRLYYSLDAGNKTMVLPLLNEAAAFFIQQGQEEDAVKQA 352 G+ DE+R E L+ +LYY++D GN + LL AA+ +++ E+ +K+A Sbjct: 297 -----GNTDEERQPYDPEQLMEQLYYAVDVGNVEVQQKLLYTAASAMVKEEYTEERMKRA 351 Query: 353 FFFLSNRLIHKLTAASRIELKETETVSRFLNGIYQQDYLSDLLEETHRFLLEFAEDAGPK 412 F L + +KL T+ S + I++Q DL + +FL E AG Sbjct: 352 FVELLTGVHNKLMQHHTELQSRTKEYSDRIAAIFRQRTAYDLCRHSSQFLEELIWQAGNG 411 Query: 413 GKEQEIKQMTGFIHRHYAEDLKLSTLAGLLNYSTPYLGQLFRNKTGEYFNTYLDKVRIQK 472 G++QE+K++ I R+Y E++KL TLA + NY++ YLG++F+N TGEYFNTYLDKVRI K Sbjct: 412 GRDQEMKRIMDLIQRNYNENIKLETLASIFNYNSAYLGKMFKNTTGEYFNTYLDKVRIDK 471 Query: 473 AKELLAQGMKVYEAAELVGYTSVNYFFSKFKKYEGRSPSDYK 514 AK+ L QGMKVY+ AE VGYT+V+YF SKFKKY G SPS+++ Sbjct: 472 AKDFLKQGMKVYQVAEKVGYTNVDYFHSKFKKYVGTSPSNFR 513 >B1D7X3.1 B1D7X3_9BACL Two component transcriptional regulator, AraC family Length = 507 Score = 293 bits (749), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 190/520 (36%), Positives = 281/520 (54%), Gaps = 23/520 (4%) Query: 1 MIKVVIVDDEPKLRQGLQTLIPWENLGFTVTAAAGNGRDALKIVEEEVPDLVIADIRMPV 60 M KV++VDDEP +R+GL+TL+ WE+LG+ V A NG+DAL+ E+ DL+I DIRMP Sbjct: 1 MYKVLLVDDEPMIREGLRTLLEWESLGYEVVDTAANGKDALQKCEQHDLDLIIVDIRMPE 60 Query: 61 MDGLQFIQRLRSAGHQMHCIILSGYADFEYAKQAITYGVAGYLVKPVNIAEMSATL-KLV 119 M+GL+ I+++R G MH +ILSGYADFEYAKQAI + GYL+KPV+ E+ L L Sbjct: 61 MNGLELIKKIRENGGTMHVLILSGYADFEYAKQAIVQRIDGYLLKPVDEDELMEYLHSLR 120 Query: 120 XXXXXXXXXXXXWYRTEVTNRELYLRRLLAPQEKTEDPAKLRSRIREMDLLWSHYEIVVI 179 N E L+RLL E W +E+++I Sbjct: 121 KELDLEYETRQKRLDERQGNAEDDLKRLL-----VEGSTGSSLSPLSASPDWKEFELLLI 175 Query: 180 SPRVPEADRPEHLHQLSAGLKHGIEGRNRGLVTVIAPYVILLLNSPLHGRQRRDHLYGEI 239 + Q+ L ++ GL + PY+++LLN L + R ++ I Sbjct: 176 KTHERNEEETAGHAQIKRRLSERLDQSGGGLAIAMEPYLLVLLNKGLDNERFRRDMHAMI 235 Query: 240 ----RSIAGDTRFIAATGGTVSEPELIYSAFLKAQEAVKQVFFSAKDCLLEPERTLFAAP 295 +A D F +GG S I +A+ KA E +K FF L+ + P Sbjct: 236 ADACEGLASD--FTVVSGGNASGNADIQAAYQKALERMKNRFF------LKGGQITAEDP 287 Query: 296 EFPREAGDRDEK-RMEDLIFRLYYSLDAGNKTMVLPLLNEAAAFFIQQGQEEDAVKQAFF 354 + P AG D K + +LY +L+ N+ + + E+A G E +K AF Sbjct: 288 QMP--AGSEDAKPDLTGTAEKLYLALEIVNREAIRQQIEESAEAMKAIGFGEAEMKAAFV 345 Query: 355 FLSNRLIHKLTAASRIELKETETVSRFLNGIYQQDYLSDLLEETHRFLLEFAEDAGPKGK 414 L + ++ KL A+ R EL+ + R + ++++ +S L + + A+ Sbjct: 346 ELVSAVLDKL-ASKRPELQVRDYRQR-IPELFREYRISSLTRLATAIIDQIADSLDNSSA 403 Query: 415 EQEIKQMTGFIHRHYAEDLKLSTLAGLLNYSTPYLGQLFRNKTGEYFNTYLDKVRIQKAK 474 +++IK+M IHR+Y E+LK+ TLA L NY++ YLG+LF+ TGE FNTYLDKVR+++AK Sbjct: 404 DKQIKRMIDLIHRNYKENLKMETLAELFNYNSAYLGKLFKQVTGENFNTYLDKVRMEQAK 463 Query: 475 ELLAQGMKVYEAAELVGYTSVNYFFSKFKKYEGRSPSDYK 514 LL QG+KVY+ AE+VGY +V+YF SKF+KY G SPS Y+ Sbjct: 464 ILLEQGLKVYQVAEMVGYANVDYFHSKFRKYVGSSPSVYR 503 >Q9KBL6.1 Q9KBL6_BACHD Two-component response regulator Length = 506 Score = 267 bits (683), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 175/522 (33%), Positives = 267/522 (51%), Gaps = 35/522 (6%) Query: 1 MIKVVIVDDEPKLRQGLQTLIPWENLGFTVTAAAGNGRDALKIVEEEVPDLVIADIRMPV 60 M V+IVDDE +R+GL+ LI WE GF V A NG++ + PDL+I DIRMP Sbjct: 1 MYDVMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPE 60 Query: 61 MDGLQFIQRLRSAGHQMHCIILSGYADFEYAKQAITYGVAGYLVKPVNIAEMSATLKLVX 120 +DGL I+ +R+ +H IILSG++DF YAK+A+ YL+KP++ E+ +LK V Sbjct: 61 VDGLSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKVY 120 Query: 121 XXXXXXXXXXXWY-RTEVTNRELYLRRLLAPQEKTEDPAKLRSRIREMDLLWSHYEIVVI 179 R + E+ L LL +E P +E + + Y++ ++ Sbjct: 121 GRITRHHQVHELVERVQEKQVEMVLTELLEGTPLSEIPIG-----KEHNFFATDYQVALV 175 Query: 180 SPRVPEADRPEHLHQLSAGLKHGIEGRNRGLVTVIAPYVILLLNSPLHGRQRRDHLYGEI 239 R DR L+ LK IE + G V Y++++ + ++ +DH Y Sbjct: 176 ENR---QDR------LTKQLKRLIEEQEEGYVIPFPEYIVIVCKNRFLQKRGKDHRYHLF 226 Query: 240 RSIAGDTRFIAATGGTVSEPELIYSAFLKAQEAVKQVFFSAKDCLLEPE----RTLFAAP 295 + A G V IY ++ A+ ++ FF K L + R+ AP Sbjct: 227 AKWLEEEELHACAGSKVVNLADIYESYQSAKRLYEKKFFVEKGRLFTADQLVDRSKPEAP 286 Query: 296 EFPREAGDRDEKRMEDLIFRLYYSLDAGNKTMVLPLLNEAAAFFIQQGQEEDAVKQAFFF 355 EF +E RLYYS+D GN + ++ E I QEE +K A F Sbjct: 287 EFS----------LESYADRLYYSIDIGNMEGCVAIIEELKNVVIVHLQEEKEIKVALFQ 336 Query: 356 LSNRLIHKLTAASRIELKETETVSRFLNGIYQQDYLSDL---LEETHRFLLEFAEDAGPK 412 L + ++H+L + E + IYQ ++L + L + +++++ ++ P Sbjct: 337 LYSNILHQLVRSHPNMEGVLEPLVMNAGDIYQFEHLPGIMAFLTKQLKYVIDCMDNGQP- 395 Query: 413 GKEQEIKQMTGFIHRHYAEDLKLSTLAGLLNYSTPYLGQLFRNKTGEYFNTYLDKVRIQK 472 + +++M IH+ YA++L+L TLA + NY+ YLG+LF+N TGEYFNTYLDKVRI+ Sbjct: 396 --DLLLRKMIALIHKDYAKNLRLETLASVFNYNRAYLGKLFKNYTGEYFNTYLDKVRIEN 453 Query: 473 AKELLAQGMKVYEAAELVGYTSVNYFFSKFKKYEGRSPSDYK 514 K LL +G KVYE AE +GY +V+YF KFKKY G SPS ++ Sbjct: 454 GKRLLQKGYKVYEVAEKIGYANVDYFHRKFKKYVGVSPSTFR 495 >Q5WIY3.1 Q5WIY3_BACSK Two-component response regulator Length = 493 Score = 238 bits (608), Expect = 9e-61, Method: Compositional matrix adjust. Identities = 174/519 (33%), Positives = 269/519 (51%), Gaps = 32/519 (6%) Query: 1 MIKVVIVDDEPKLRQGLQTLIPWENLGFTVTAAAGNGRDALKIVEEEVPDLVIADIRMPV 60 M KV+I DDE +R+G++ LIPWE+ GF V + A NG+DAL+ + + PDLVIADIRMP Sbjct: 1 MYKVLIADDEWMIREGVKNLIPWEHYGFEVASLACNGKDALEKYKHDKPDLVIADIRMPQ 60 Query: 61 MDGLQFIQRLRSAGHQMHCIILSGYADFEYAKQAITYGVAGYLVKPVNIAEMSATLKLVX 120 MDGL ++ +R+ + ++LSG+ADF YA++AI +GV GYL+KP+ E+ L++V Sbjct: 61 MDGLSLLKEIRTENEAVPFLLLSGHADFHYAQEAIGHGVDGYLLKPLEEDELIEHLQIVF 120 Query: 121 XXXXXXXXXXXWYRTEV-TNRELYLRRLLAPQEKTEDPAKLRSRIREMDLLWSHYEIVVI 179 + V +E L LLA + P + L S Y+I ++ Sbjct: 121 HKLEQRKQAHVLRQQSVRIEQERLLLNLLAGK-----PLPTSVDFSRLGLAASRYQIFLV 175 Query: 180 SPRVPEADRPEHL-HQLSAGLKHGIEGRNRGLVTVIAPYVILLLNSPLHGRQRRDHLYGE 238 E D EHL Q+ +G + GL+ I L S L +Q HL Sbjct: 176 --HAGERDALEHLAEQIPHTAVPFAKGGDAGLL--ICHLQEGLTKSEL--QQWASHLLAP 229 Query: 239 IRSIAGDTRFIAATGGTVSEPELIYSAFLKAQEAVKQVFFSAKDCLLEPERTLFAAPEFP 298 +R A G V + I ++ A++ + F++ K ++ T+ Sbjct: 230 MRH--------GALGKCVRKLSAIQVSYTAAKKLLSLAFYADKGSVISELPTVL------ 275 Query: 299 REAGDRDEKRMEDLIFRLYYSLDAGNKTMVLPLLNEAAAFFIQQGQEEDAVKQAFFFLSN 358 + G +K + R+Y +L G K +++ A + +E ++K L+ Sbjct: 276 -QDGQLAKKPLSFYEERIYLALHIGEKEPAKQAVSDFLADVAARRMKEASLKAKASELAL 334 Query: 359 RLIHKLTAASRIELKETETVSRFLNGIYQ-QDYLSDLLEETHRFLL-EFAEDAGPKGKEQ 416 +I +L A+ + + + RF + + +D+L L R L E A + + + Sbjct: 335 NVIQRLIASHVLAKEWAQKGYRFTAQLQEAEDFLQ--LRHVLRCLCDELAANTNVRSNDT 392 Query: 417 EIKQMTGFIHRHYAEDLKLSTLAGLLNYSTPYLGQLFRNKTGEYFNTYLDKVRIQKAKEL 476 +K+M I Y E+L+L T++ +LNY++ YLG+ F+ +TG+YFNTYLDKVRI K+KEL Sbjct: 393 AVKKMIDMIDSRYDENLRLETISAVLNYNSAYLGKRFKQETGDYFNTYLDKVRIHKSKEL 452 Query: 477 LAQGMKVYEAAELVGYTSVNYFFSKFKKYEGRSPSDYKN 515 L G KVYEAAE VGY +V+YF KFKKY G SPS ++ Sbjct: 453 LRAGCKVYEAAEKVGYPNVDYFHRKFKKYTGMSPSAFRK 491 >B9MLE2.1 B9MLE2_ANATD Two component transcriptional regulator, AraC family Length = 519 Score = 214 bits (545), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 151/524 (28%), Positives = 256/524 (48%), Gaps = 21/524 (4%) Query: 1 MIKVVIVDDEPKLRQGLQTLIPWENLGFTVTAAAGNGRDALKIVEEEVPDLVIADIRMPV 60 M KVV++DDEP + +GL+ ++ W LGF + A A +G D + E PD+ + DIR+P Sbjct: 1 MFKVVLIDDEPIIIEGLKKILDWHALGFEIVAVAYDGVDGFSKLLELNPDVALIDIRIPG 60 Query: 61 MDGLQFIQRLRSAGHQMHCIILSGYADFEYAKQAITYGVAGYLVKPVNIAEMSATLKLVX 120 +DGL IQRLR IILSGY++FEYA++A+ GV YL+KP++ + L + Sbjct: 61 IDGLLLIQRLREKNISTKIIILSGYSEFEYARKAVELGVESYLLKPIDKQLLEEKLMAIR 120 Query: 121 XXXXXXXXXXXWYRT--EVTNRELYLRRLLAPQEKTEDPAKLRSRIREMDLLWSHYEIVV 178 + ++T ++ + +L + TE + ++ E+ L W Y++ + Sbjct: 121 EKLEEEFKINRAFSAAKKLTREKVVEKLVLGTLKDTE--IEYMNKFFELQLPWKKYQVAI 178 Query: 179 ISPRVPEADRPEHLHQLSAGLKHGIE---GRNR-GLVTVIAPYVILLLNS---PLHGRQR 231 I + E ++Q LK ++ +N G T+I + +L P + R Sbjct: 179 IQL-LNENRNSCEINQTVLQLKEKVDLFLNKNSCGFSTIINNNICILFKDFWYPFNSRSI 237 Query: 232 RDHLYGEIRSIAGDTRFIAATGGTVSEPELIYSAFLKAQEAVKQVFFSAKDCLLEPERTL 291 ++ ++ D + I + G V + I +F +A E +K+ F L+ + + Sbjct: 238 --NILKDMLMKYTDGQIIISIGSEVEDYRNIKKSFEEANELLKKRFLLGYKGLIFIKEAI 295 Query: 292 FAAPEFPREAGDRDEKRMEDLIFRLYYSLDAGNKTMVLPLLNEAAAFFIQQGQEEDAVKQ 351 F + +E D++ + L +++ N + +L A I++ ED K Sbjct: 296 FRYDKTEKEFDDKENA------YALAVAIEFENFERINNILENKADNLIKKNASEDEAKS 349 Query: 352 AFFFLSNRLIHKLTAASRI-ELKETETVSRFLNGIYQQDYLSDLLEETHRFLLEFAEDAG 410 +F+ +++KL+ ++ E ++ Q L++L + AE Sbjct: 350 SFYNFFVDVLYKLSQNQEYKQIVEKYLTQEIFKNLFTQKTLTELKGLIKYYFTLIAEQIK 409 Query: 411 PKGKEQEIKQMTGFIHRHYAEDLKLSTLAGLLNYSTPYLGQLFRNKTGEYFNTYLDKVRI 470 + Q+ FI R+Y DLKL TLA + Y++ Y +LF+ GE F+++++KVRI Sbjct: 410 KLHSDNFKVQVEEFIKRNYFIDLKLETLAEIFGYNSSYFSKLFKKTFGENFSSFIEKVRI 469 Query: 471 QKAKELLAQGMKVYEAAELVGYTSVNYFFSKFKKYEGRSPSDYK 514 +KAKELL G KV E A+ VGY ++YF KFKKY G SP YK Sbjct: 470 EKAKELLENGKKVSEVAKKVGYEDMDYFCLKFKKYVGCSPKSYK 513 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.137 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,900,566,660 Number of extensions: 118667407 Number of successful extensions: 360949 Number of sequences better than 1.0e-05: 11435 Number of HSP's gapped: 375610 Number of HSP's successfully gapped: 12028 Length of query: 516 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 376 Effective length of database: 1,741,754,103 Effective search space: 654899542728 Effective search space used: 654899542728 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)