BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0596.0018.p (590 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K432.1 B3K432_9BACI Histidine kinase internal region 285 1e-74 A7VUS2.1 A7VUS2_9CLOT Putative uncharacterized protein 248 1e-63 C0C1J1.1 C0C1J1_9CLOT Putative uncharacterized protein 239 5e-61 B3KJG0.1 B3KJG0_9BACI Histidine kinase internal region 232 7e-59 A9KIC4.1 A9KIC4_CLOPH Multi-sensor signal transduction histidine... 222 1e-55 >B3K432.1 B3K432_9BACI Histidine kinase internal region Length = 600 Score = 285 bits (729), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 170/548 (31%), Positives = 281/548 (51%), Gaps = 20/548 (3%) Query: 52 ELNRQMTTSTDAFLKNMLRVSETPFYDQELLNILSKDYGTFEYPIYEKSSDYKYINDEFF 111 E N+Q+ + D L+ +LR+S P D + I+ KDYG YP+ E+ D+ +N Sbjct: 54 ENNKQIIKNIDTSLQPLLRLSMFPIQDSTVYPIMRKDYGKVTYPLLERGQDFDKVNGLIQ 113 Query: 112 RKIFLFNNDIDSLVIYADNNEVAYRKGYQVIYNYDY---QPFDEPWFRQIEAKRGQPVVV 168 I L+++ IDS+VIY +N+ + + N+ Y Q E + R+I G V + Sbjct: 114 SGIMLYSDLIDSVVIYHENSRSIIGRSNREYMNFAYFKEQFTRERFVRKIREAYGGFVPI 173 Query: 169 GLHPEKXXXXXXX-XXXXXXXIVDPATNQKLGTFIVNFRDGTLRKLYQGLNPGPEAEQMI 227 G+H E+ I+DP T + LG + N L+ L+ + Sbjct: 174 GIHQERLLSTKGIPVVSVGRAILDPYTKEDLGFILFNISVDKLKTLWSDSAFSENTNFYL 233 Query: 228 VDENNKILFSTVSRAIGLNLEDQVRQD-------------DPEYYIVHNTSAISGWKFYS 274 +DE + I+ S IGL + + D + + Y++ ++S+++ WK + Sbjct: 234 IDETDHIVHSVHPEEIGLAASEVLGSDFQYKADGQVNTQINRDTYMISSSSSMANWKAVT 293 Query: 275 IIHKQAMFHEVYQIRNXXXXXXXXXXXXXXCVALLVSRGITNPIKQLSRMMRRVEIGDFN 334 +I K+ +F VY + ++ ++ I P+ L+ M+ V G + Sbjct: 294 VIPKKDLFSIVYLMVAILIGALILLLVLSILISARIATTIMKPLAVLNSKMKLVSQGQLD 353 Query: 335 VNIDMNRQDEIGRLGYAFNAMTKEIQQLIARIKEEEHQKRSAELNALQAQINPHFLYNTL 394 V+ D + EIG + + + M EI+ LI RI EE +KR+ E+NALQ+QI PHF+YNTL Sbjct: 354 VSFDTKQHGEIGVISHTVDQMLHEIRDLIERIYVEEEEKRNLEMNALQSQIRPHFIYNTL 413 Query: 395 SVVRWMSQAQMADNITETLDSLIGLLAFSARNTKEFVSIEEEMAFIQNYVTLLELRYYNT 454 +V++WM++ Q A I E L + ++ F+ + ++V+I EE+ F++NY +L+ RY N Sbjct: 414 NVIKWMAKIQGATGIEEALQAFSSVIKFTVKKEGDYVTIAEEVEFMENYTKILDFRYLNK 473 Query: 455 FEATYHVEAEVRHYQTLKFIVQPFVENAIFHGFADEKHTYRLSIDVRRHEKGVRFMIKDN 514 F+ TY V+ V +++TLKF++QP VENA+FHGF + L I + + + DN Sbjct: 474 FDVTYEVDPAVMNHRTLKFLLQPLVENAVFHGFEGIDYKGSLVISIYEESDALIMKVCDN 533 Query: 515 GIGMSHEQIERLMDKGKGQQGMNSIGVRNVSERIQLHFGPQYGVQIHTLSGEGTTIFIDI 574 G G ++ G Q NSIG+ N+ RI LHFGP+YG+ I GT ++ + Sbjct: 534 GRGFPEGGQAKVEQDGP-QDTFNSIGLNNIRNRISLHFGPEYGLWIQRGEQGGTVAWLRV 592 Query: 575 PVLINTEE 582 P++ TEE Sbjct: 593 PII--TEE 598 >A7VUS2.1 A7VUS2_9CLOT Putative uncharacterized protein Length = 590 Score = 248 bits (633), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 157/543 (28%), Positives = 278/543 (51%), Gaps = 18/543 (3%) Query: 54 NRQMTTSTDAFLKNMLRVSETPFYDQELLNILSKDYGTFEYPIYEKSSDYKYINDEFFRK 113 N Q+ S D F ++ ++S++ +EL IL Y E + + D + + + +R Sbjct: 46 NNQIIYSLDDFFNSLSKISDSLLMSEELTRILQNTYQDPEAQL-QNYRDKRQVEELLYRN 104 Query: 114 IFLFNNDIDSLVIYADNNEVAYRKGYQVIYNYDYQPFDEPWFRQIEAKRGQPVVVGLHPE 173 + +N I+++ I+ +N+++ Y + I N Y +E W+ +I K G ++G+H Sbjct: 105 GYYLDNRIETIAIFPENSDMFYYCTKETI-NPAYDVREEKWYSRILEKEGAQALIGIHQN 163 Query: 174 KXXXXXXXXXXXXXXIVDPAT-----NQKLGTFIVNFRDGTLRKLYQGLNPGPEAEQMIV 228 + + ++ LGT I+N L++L+ + + + +V Sbjct: 164 GLVQASFQARQPYCVTIGRSIYSAYESRLLGTIIINVNVRDLQELWPEPDQNFQEKFYLV 223 Query: 229 DENNKILFSTVSRAIG--LNLED------QVRQDDPEYYIVHNTSAISGWKFYSIIHKQA 280 D+ N+++FS S IG ++ D + Y + + S GWK +I + Sbjct: 224 DDENRVVFSDSSEEIGGQFSMSDLSVGISSCEMEGVLYDAMVSESGHQGWKSVKMIMRSK 283 Query: 281 MFHEVYQIRNXXXXXXXXXXXXXXCVALLVSRGITNPIKQLSRMMRRVEIGDFNVNIDMN 340 + E+ + V+L +S+ T P+++L MRR E + + N Sbjct: 284 LDKEIAVVPYMTITLVLVLIGLAVLVSLFISKIFTRPLQELYVKMRRFE-AEKSGNPLPE 342 Query: 341 RQDEIGRLGYAFNAMTKEIQQLIARIKEEEHQKRSAELNALQAQINPHFLYNTLSVVRWM 400 Q EI L ++N M +EI L + E E Q R AEL ALQ+QINPHF+YNTL+ ++W+ Sbjct: 343 NQVEIKGLSRSYNRMIEEINSLTIKNYETELQLRRAELMALQSQINPHFIYNTLNSIKWL 402 Query: 401 SQAQMADNITETLDSLIGLLAFSARNTKEFVSIEEEMAFIQNYVTLLELRYYNTFEATYH 460 + Q + + LDSLI L+ FS++N++E + I++E+ I++Y+ L+ L+Y++ Sbjct: 403 ADMQGSKRMVTALDSLIKLMQFSSKNSQEVIRIQDEIDLIKDYINLINLKYFDRIVTLIR 462 Query: 461 VEAEVRHYQTLKFIVQPFVENAIFHGFADEKHTYRLSIDVRRHEKGVRFMIKDNGIGMSH 520 VE V Y+TLKF++QP VEN+I+HGF + + I++ R + + + DNG GMS Sbjct: 463 VEPGVERYETLKFLLQPIVENSIYHGFNKMTQSCAIKINISRKGDRILYEVIDNGKGMSR 522 Query: 521 EQIERLM--DKGKGQQGMNSIGVRNVSERIQLHFGPQYGVQIHTLSGEGTTIFIDIPVLI 578 E+I + + ++ + N IG+ NV++RIQ FG YGV+I + G T + ++IP + Sbjct: 523 EKIRQALKEERSENSHSFNKIGLYNVNKRIQYTFGGDYGVKIDSELGRYTRVLVEIPARV 582 Query: 579 NTE 581 E Sbjct: 583 YKE 585 >C0C1J1.1 C0C1J1_9CLOT Putative uncharacterized protein Length = 601 Score = 239 bits (611), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 163/605 (26%), Positives = 288/605 (47%), Gaps = 35/605 (5%) Query: 1 MRLIRFKDRSMNQKLFLTYVFXXXXXXXXXXXXXXXXXXXFLEGRIVHSFKELNRQMTTS 60 M++I++KD M KLF+ ++ + +++ S +E QM + Sbjct: 1 MKIIKYKDLKMKNKLFIGFILVIAVLVSLLGYFSMTFSEQSIRTQMLDSIQETMNQMGEN 60 Query: 61 TDAFLKNMLRVSETPFYDQELLNILSKDY-GTFEYPIYEKSSDYKYINDEFFRKIFLFNN 119 + ++ +L VS ++EL +L ++ GT E Y K + I +E + F Sbjct: 61 IEGEIQKVLDVSAQVCLNEELCTVLQEEKPGTIE-EYYSKDKTMRQILNESYAAYF---- 115 Query: 120 DIDSLVIYADNNEVAYRKGYQVIYNYDYQPFDEPWFRQIEAKRGQPVVVGLHPEKXXXXX 179 ++ + + + N V ++ DY WF ++ + G V + + Sbjct: 116 SVEDVFVCSYNGSVYGSDKNKLSLTADYDFTRTGWFADMK-QSGAGVSILSQYDSSSYIS 174 Query: 180 XXXXXXXXXIVDPATN----QKLGTFIVNFRDGTLRKLYQGLNPGPEAEQMIVDENNKIL 235 IV N +++G IV+ L + Q +N + +I+D N KI+ Sbjct: 175 TGEPQKLFSIVKKIYNYRSGKEIGCLIVHMNSDILGNVLQSVNSNEYQQCLIIDNNKKII 234 Query: 236 FSTVSRAIG-----------LNLEDQVRQDDPEY-YIVHNTSAISGWKFYSIIHKQAMFH 283 + S IG L +E+ + E Y+V +TSA++GW S++ + + Sbjct: 235 YHPDSDYIGTQYREARVSELLTMENGYMESLSEKGYLVFSTSAVTGWSVISVVDNKYIMD 294 Query: 284 EVYQIRNXXXXXXXXXXXXXXCVALLVSRGITNPIKQLSRMMRRVEIGDFNVNIDMNRQD 343 + ++R A +S+ I++P+ +L R M +V GDF++ D Sbjct: 295 SINRLRLFLILTAVFCVVLSVYFASYISKTISDPVARLQRKMYQVGEGDFDIRAATGASD 354 Query: 344 EIGRLGYAFNAMTKEIQQLIARIKEEEHQKRSAELNALQAQINPHFLYNTLSVVRWMSQA 403 EIG+L +F+ M + +QLI + + E ++ AELNALQAQINPHFLYNTL + M++ Sbjct: 355 EIGQLTLSFDKMVERTKQLIENVYQSEIYQKEAELNALQAQINPHFLYNTLQTIDMMAEE 414 Query: 404 QMADNITETLDSLIGLLAFSARNTKEFVSIEEEMAFIQNYVTLLELRYYNTFEATYHVEA 463 + AD I++ +L + +S +EFV +++E+ I+NY+ + +LR+ E Y ++ Sbjct: 415 EGADEISDACQALSKIFRYSINRGQEFVHVQDEIVHIENYMLIQKLRFGGKLEVRYDIQN 474 Query: 464 EVRHYQTLKFIVQPFVENAIFHGFADEKHTYRLSIDVRRHEKGVRFMIKDNGIGMSHEQI 523 E R +K ++QP VENA+ HG + ++I V R E + ++DNG G++ Q+ Sbjct: 475 ECRELYIVKLLIQPMVENAVVHGMENVLDKCYVTIRVYRKEDCLYAEVEDNGTGIAPGQL 534 Query: 524 ERLMDK--GKGQQGM----------NSIGVRNVSERIQLHFGPQYGVQIHTLSGEGTTIF 571 L +K +Q M SIG+ N + RI+L+FG +YG+ I + G GT + Sbjct: 535 MELNEKLARSAEQKMVHEVDYVKNHRSIGLENTNARIKLYFGQEYGITITSEEGTGTKVC 594 Query: 572 IDIPV 576 I +PV Sbjct: 595 IKLPV 599 >B3KJG0.1 B3KJG0_9BACI Histidine kinase internal region Length = 598 Score = 232 bits (592), Expect = 7e-59, Method: Compositional matrix adjust. Identities = 140/498 (28%), Positives = 245/498 (49%), Gaps = 24/498 (4%) Query: 109 EFFRKIFLFNNDIDSLVIYADNNEVAYRKGYQVIYNYDYQPF----DEPWFRQIEAKRGQ 164 ++F I + DI S+ I+ + N + P+ D+PW+RQ + +GQ Sbjct: 104 DYFHSIRISRKDIASINIFGAGGTFISDRS-----NAELNPYIEISDQPWYRQAKENQGQ 158 Query: 165 PVVVGLHPEKXXXXX-XXXXXXXXXIVDPATNQKLGTFIVNFRDGTLRKLYQGLNPGPEA 223 V+ H + + + Q LG +++ + + L+ G Sbjct: 159 TVISSSHVQPVIKGEYRWVVSLSRELSGMDSTQGLGILLIDLNFKVINDMLSKLDLGNRG 218 Query: 224 EQMIVDENNKILFSTVSRAIGLNLE----DQVRQDDPEYYIVHNTSAIS---------GW 270 ++D +I++ + + NL+ DQV QD ++V A GW Sbjct: 219 YVFVIDREGRIVYHPQQQLLYSNLKTERLDQVLQDKHGSFVVKEDGASRIYSIKNTDFGW 278 Query: 271 KFYSIIHKQAMFHEVYQIRNXXXXXXXXXXXXXXCVALLVSRGITNPIKQLSRMMRRVEI 330 K + ++ + Q++ ++++SR +T PIK+L M VE Sbjct: 279 KIVGVFYENELVDNKKQMQLSFAIAGLLCLVVGVLFSVVLSRNLTRPIKKLQEKMMEVEK 338 Query: 331 GDFNVNIDMNRQDEIGRLGYAFNAMTKEIQQLIARIKEEEHQKRSAELNALQAQINPHFL 390 G+F++ + + EI L +FN M +I++L+ +I E+ KR +ELNALQAQINPHFL Sbjct: 339 GNFDIRVPVGHSREISGLARSFNVMVLKIKELMYQIVVEQEIKRKSELNALQAQINPHFL 398 Query: 391 YNTLSVVRWMSQAQMADNITETLDSLIGLLAFSARNTKEFVSIEEEMAFIQNYVTLLELR 450 YNTL + WM++++ D + +L L S KE + I E+ I NY+ + ++R Sbjct: 399 YNTLDSIIWMAESKKHDEVILMTSALARLFRASLSKGKELIPIATEVEHITNYLKIQQMR 458 Query: 451 YYNTFEATYHVEAEVRHYQTLKFIVQPFVENAIFHGFADEKHTYRLSIDVRRHEKGVRFM 510 Y + ++ + Y TLK ++QP VENAI+HG +++ ++I R + + F Sbjct: 459 YQDKITFALDIDRGLYPYLTLKVLLQPLVENAIYHGIKNKEGPGTITITGVRRDTRIEFQ 518 Query: 511 IKDNGIGMSHEQIERLMDKGKGQQGMNSIGVRNVSERIQLHFGPQYGVQIHTLSGEGTTI 570 +KD+GIGM ++E L+ +G + NS+G+ NV +RIQL+FG +YG+ ++ G GT++ Sbjct: 519 VKDDGIGMDQSKVETLLTSKEGTRSRNSVGIANVHQRIQLYFGTEYGLSYASVPGSGTSV 578 Query: 571 FIDIPVLINTEEPSAKEG 588 + IP ++ +E EG Sbjct: 579 TLVIPA-VHADEWQRVEG 595 >A9KIC4.1 A9KIC4_CLOPH Multi-sensor signal transduction histidine kinase Length = 585 Score = 222 bits (565), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 146/539 (27%), Positives = 256/539 (47%), Gaps = 22/539 (4%) Query: 52 ELNRQMTTSTDAFLKNMLRVSETPFYDQELLNILSKDYGTFEYPIYEKSSDYKYINDEFF 111 EL QM + D+++ M +S+ D ++ L+ DY + + K + +N F Sbjct: 49 ELINQMNSDVDSYIGYMENISQLALLDSDVHTFLNSDYEELDSRQFAKE---RVMNQ--F 103 Query: 112 RKIFLFNNDIDSLVIYADNNEVAYRKGYQVIYNYDYQPFDEPWFRQIEAKRGQPVVVGLH 171 I +DI +L I N +G I Y + W+++ A G+ + H Sbjct: 104 GTILDLRSDITNLAIIGTNGRYILNRGEDEINPY-LDVKQKEWYKKAIAGNGKIYISSSH 162 Query: 172 PEKXXXXXXX-XXXXXXXIVDPATNQKLGTFIVNFRDGTLRKLYQGLNPGPEAEQMIVDE 230 + I D +++ +G +V+ + L + +N G + ++DE Sbjct: 163 VQNIVNGKYQWVVSLSRAIKDKESDEMIGALLVDLNYNVINNLCKKINLGYKGYIFLLDE 222 Query: 231 NNKILFSTVSRAI--GLNLED--QVRQDDPEYYIVHNT---------SAISGWKFYSIIH 277 I++ + I GL E +V++ Y++ T S +GW + + Sbjct: 223 EGNIIYHPKQQLIYNGLINEKTLEVKECKESYFLTEGTDRKLYVISRSEKTGWTAVGVAN 282 Query: 278 KQAMFHEVYQIRNXXXXXXXXXXXXXXCVALLVSRGITNPIKQLSRMMRRVEIGDFNVNI 337 +F + Q + +++L+SR IT PIK+L M+ VE G+F+ + Sbjct: 283 VSELFLQREQTQRLYLISTVAILLIAMLLSILISRAITKPIKKLRDSMKEVEKGNFHEKV 342 Query: 338 DMNRQDEIGRLGYAFNAMTKEIQQLI-ARIKEEEHQKRSAELNALQAQINPHFLYNTLSV 396 + + DEI LG ++N M + + +L+ AR+K++E QKR +EL ALQAQINPHFLYNTL Sbjct: 343 ETSGSDEIANLGKSYNIMIQTVDELMEARVKDQE-QKRKSELRALQAQINPHFLYNTLDS 401 Query: 397 VRWMSQAQMADNITETLDSLIGLLAFSARNTKEFVSIEEEMAFIQNYVTLLELRYYNTFE 456 + WM++ + SL L S N E ++ +E+ +++NY+ + ++RY Sbjct: 402 IVWMAEEGKNQEVVTMTASLAKLFRQSISNEAEEFTLRQEVDYVRNYLVIQKMRYKEQLN 461 Query: 457 ATYHVEAEVRHYQTLKFIVQPFVENAIFHGFADEKHTYRLSIDVRRHEKGVRFMIKDNGI 516 V + +Y +K I+QP VENA++HG + + +D E V + D+GI Sbjct: 462 YDIQVPESILNYYVIKLILQPLVENALYHGVKYKDGVGTIFVDGYETESTVVLQVIDDGI 521 Query: 517 GMSHEQIERLMDKGKGQQGMNSIGVRNVSERIQLHFGPQYGVQIHTLSGEGTTIFIDIP 575 GM E++ L +K K + + +RN+ RIQLH+G ++G+ + G GT + I +P Sbjct: 522 GMDEEELSHLFEKRKSTHKTSRVAIRNIHNRIQLHYGKEFGLSFESKKGYGTKVMITLP 580 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.322 0.138 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,107,803,333 Number of extensions: 123903102 Number of successful extensions: 330449 Number of sequences better than 1.0e-05: 2419 Number of HSP's gapped: 327924 Number of HSP's successfully gapped: 2420 Length of query: 590 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 448 Effective length of database: 1,722,912,073 Effective search space: 771864608704 Effective search space used: 771864608704 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 134 (56.2 bits)