BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0591.0029.p (453 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q314Z4.1 Q314Z4_DESDG Xanthine/uracil permease family protein 222 6e-56 C1FQI1.1 C1FQI1_CLOBJ Xanthine/uracil permease family protein 205 9e-51 A7FPX5.1 A7FPX5_CLOB1 Xanthine/uracil permease family protein 204 1e-50 A5I3W0.1 A5I3W0_CLOBH Xanthine/uracil permease family protein 204 1e-50 C3KYW4.1 C3KYW4_CLOB6 Xanthine/uracil permease family protein 204 1e-50 >Q314Z4.1 Q314Z4_DESDG Xanthine/uracil permease family protein Length = 435 Score = 222 bits (566), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 137/417 (32%), Positives = 228/417 (54%), Gaps = 11/417 (2%) Query: 4 THSEEQVLTVGIEEKLSIGANVTYGFQHLLALTGIFLFPVLIGQALGLDASIIGYMIQAC 63 + + E LTVG++E +S G QH+LA+ +++ P ++ L L IQ Sbjct: 2 SRNTELHLTVGVDEPVSPLKAFALGLQHVLAMD-VYIAPFVMAGLLSLSVPETATFIQMT 60 Query: 64 FLTTGIVTVLQSGKMLRLPVVQGPTAAFFVAVLSAGSTVGLGTAFGSMAVAGLIFMLLSI 123 F+ G+ T++Q+G +RLPV+QGP+ A+ + G+++GLG FGS+ L+ LL Sbjct: 61 FVAAGLATLIQAGFGIRLPVMQGPSYVPIGALAAIGNSLGLGAMFGSLLPGALVMTLLGK 120 Query: 124 PVRRFGLIGYLNKFISPPIVYGTLLIIIGAQLADIGLKNWFGS-ADTGINFAASXXXXXX 182 P+R F I +F PP+V GT+++I+G L + LK +G D N + Sbjct: 121 PLRVFSRI---VRFFIPPLVGGTVIVIVGIALMPVALKGCYGYFGDPAHNAVVALVSAAV 177 Query: 183 XXXXXXFGG-----NTILRRGALLWGIIAGTIFYSIFGTTNFSSVAAAGWFSFPDVFPFG 237 G N ++R G++++ + AGT+ + FG NF SVAAA W + P +FP+G Sbjct: 178 LVVLTVAGSRPGRFNQVVRMGSVVFSMAAGTLTAAAFGMVNFDSVAAAPWLALPVIFPYG 237 Query: 238 F-GVSVPIVILMLLAFLQASAEAVGMYTLLTKWGNQKLDNDRVNRGLFGEFLGSTLGAVF 296 + V + ++ +L E G + + +LD++R+N G FGE +G LGA+ Sbjct: 238 TPHIDVSAALTLVFIYLVVLVETTGTWFAVEAVTGSRLDDERINGGTFGEGVGCFLGAML 297 Query: 297 GGLGTTSYPENIGIVRVSGIGSRYVTMTAGVLAIVLGLIPKVGMFIASLPGPVLSAASTI 356 GG T Y N GI+ ++G+ SR+ M G + +VLG++PK+ IAS+PGPV+S + Sbjct: 298 GGTPVTGYSTNAGIIAITGVASRWAIMAGGGILLVLGMVPKLMNVIASIPGPVISGVFAV 357 Query: 357 LFGIIAISGIQMVSKVVWDELNLVVAGSSFIISLGTMYLPAELTQNLPLAFQSIVTQ 413 + +IA++G ++V V E N++V G +++L +++PAEL LP + +V Sbjct: 358 ICVVIAMNGFRVVRTVTLSERNMLVMGLPILLTLAAVFMPAELRDRLPALVRYLVES 414 >C1FQI1.1 C1FQI1_CLOBJ Xanthine/uracil permease family protein Length = 447 Score = 205 bits (521), Expect = 9e-51, Method: Compositional matrix adjust. Identities = 130/407 (31%), Positives = 221/407 (54%), Gaps = 11/407 (2%) Query: 5 HSEEQVLTVGIEEKLSIGANVTYGFQHLLALTGIFLFPVLIGQALGLDASIIGYMIQACF 64 ++++ L VGI+EK+S+ G QH+ A+ +++ P+++ L LDA Y IQ F Sbjct: 3 NTKDTNLIVGIDEKISLRYAFFLGLQHVFAMD-LYIVPIILAGILSLDAQNTAYFIQMSF 61 Query: 65 LTTGIVTVLQSGKMLRLPVVQGPTAAFFVAVLSAGSTVGLGTAFGSMAVAGLIFMLLSIP 124 + GI T++Q+G +RLP++QGP+ A+ + GS +GL GS+ L M+L P Sbjct: 62 IAAGIATLIQTGLCMRLPIMQGPSYIPIGALAAIGSKLGLQAMVGSLIPGSLFLMILGYP 121 Query: 125 VRRFGLIGYLNKFISPPIVYGTLLIIIGAQLADIGLKNWF-GSADTGINFAASXXXXXXX 183 +R I ++KFI P IV GT+++I+G L + + N F + IN + Sbjct: 122 LRFLSKI--ISKFI-PHIVGGTVIVIVGISLMPVAMTNIFTAPGNLKINCILALISSALL 178 Query: 184 XXXXXFGGNT-----ILRRGALLWGIIAGTIFYSIFGTTNFSSVAAAGWFSFPDVFPFGF 238 G + +R +++ +I GTI S+ G +F+ V A WFSFP + PFG Sbjct: 179 VSCMMIGRKSNKFGKAVRLTSVMISLIGGTIAASLLGVVDFTPVTKAAWFSFPKLLPFGK 238 Query: 239 GV-SVPIVILMLLAFLQASAEAVGMYTLLTKWGNQKLDNDRVNRGLFGEFLGSTLGAVFG 297 V + ++ ML + E G + ++ +L ++ +NRG GE +G +GA+FG Sbjct: 239 PVFDLKAILTMLFIYAVILVETSGTWFAVSAVTGSELTDEGLNRGAVGEGIGCFVGALFG 298 Query: 298 GLGTTSYPENIGIVRVSGIGSRYVTMTAGVLAIVLGLIPKVGMFIASLPGPVLSAASTIL 357 G T Y N GI+ V+G+GSR + G++ + LG++PK+ IA +P V+S ++ Sbjct: 299 GTPMTGYSTNAGIIAVTGVGSRMAIIAGGIILVALGMLPKLMNVIACIPSAVVSGVFAVV 358 Query: 358 FGIIAISGIQMVSKVVWDELNLVVAGSSFIISLGTMYLPAELTQNLP 404 IIA++G + + +DE N+++ G +++LGT LP ++ +LP Sbjct: 359 CVIIAMNGFKSIQHEEFDERNMLLIGLPILLALGTTVLPKDILNSLP 405 >A7FPX5.1 A7FPX5_CLOB1 Xanthine/uracil permease family protein Length = 447 Score = 204 bits (520), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 130/407 (31%), Positives = 221/407 (54%), Gaps = 11/407 (2%) Query: 5 HSEEQVLTVGIEEKLSIGANVTYGFQHLLALTGIFLFPVLIGQALGLDASIIGYMIQACF 64 ++++ L VGI+EK+S+ G QH+ A+ +++ P+++ L LDA Y IQ F Sbjct: 3 NTKDTNLIVGIDEKISLRYAFFLGLQHVFAMD-LYIVPIILAGILSLDAQNTAYFIQMSF 61 Query: 65 LTTGIVTVLQSGKMLRLPVVQGPTAAFFVAVLSAGSTVGLGTAFGSMAVAGLIFMLLSIP 124 + GI T++Q+G +RLP++QGP+ A+ + GS +GL GS+ L M+L P Sbjct: 62 IAAGIATLIQTGLCMRLPIMQGPSYIPIGALAAIGSKLGLQAMVGSLIPGSLFLMILGYP 121 Query: 125 VRRFGLIGYLNKFISPPIVYGTLLIIIGAQLADIGLKNWF-GSADTGINFAASXXXXXXX 183 +R I ++KFI P IV GT+++I+G L + + N F + IN + Sbjct: 122 LRFLSKI--ISKFI-PHIVGGTVIVIVGISLMPVAMTNIFTAPGNLKINCILALISSALL 178 Query: 184 XXXXXFGGNT-----ILRRGALLWGIIAGTIFYSIFGTTNFSSVAAAGWFSFPDVFPFGF 238 G + +R +++ +I GTI S+ G +F+ V A WFSFP + PFG Sbjct: 179 VGCMMIGRKSNKFGKAVRLTSVMISLIGGTIAASLLGVVDFTPVTKAAWFSFPKLLPFGK 238 Query: 239 GV-SVPIVILMLLAFLQASAEAVGMYTLLTKWGNQKLDNDRVNRGLFGEFLGSTLGAVFG 297 V + ++ ML + E G + ++ +L ++ +NRG GE +G +GA+FG Sbjct: 239 PVFDLKAILTMLFIYAVILVETSGTWFAVSAVTGSELTDEGLNRGAVGEGIGCFVGALFG 298 Query: 298 GLGTTSYPENIGIVRVSGIGSRYVTMTAGVLAIVLGLIPKVGMFIASLPGPVLSAASTIL 357 G T Y N GI+ V+G+GSR + G++ + LG++PK+ IA +P V+S ++ Sbjct: 299 GTPMTGYSTNAGIIAVTGVGSRMAIIAGGIILVALGMLPKLMNVIACIPSAVVSGVFAVV 358 Query: 358 FGIIAISGIQMVSKVVWDELNLVVAGSSFIISLGTMYLPAELTQNLP 404 IIA++G + + +DE N+++ G +++LGT LP ++ +LP Sbjct: 359 CVIIAMNGFKSIQHEEFDERNMLLIGLPILLALGTTVLPKDILNSLP 405 >A5I3W0.1 A5I3W0_CLOBH Xanthine/uracil permease family protein Length = 447 Score = 204 bits (520), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 130/407 (31%), Positives = 221/407 (54%), Gaps = 11/407 (2%) Query: 5 HSEEQVLTVGIEEKLSIGANVTYGFQHLLALTGIFLFPVLIGQALGLDASIIGYMIQACF 64 ++++ L VGI+EK+S+ G QH+ A+ +++ P+++ L LDA Y IQ F Sbjct: 3 NTKDTNLIVGIDEKISLRYAFFLGLQHVFAMD-LYIVPIILAGILSLDAQNTAYFIQMSF 61 Query: 65 LTTGIVTVLQSGKMLRLPVVQGPTAAFFVAVLSAGSTVGLGTAFGSMAVAGLIFMLLSIP 124 + GI T++Q+G +RLP++QGP+ A+ + GS +GL GS+ L M+L P Sbjct: 62 IAAGIATLIQTGLCMRLPIMQGPSYIPIGALAAIGSKLGLQAMVGSLIPGSLFLMILGYP 121 Query: 125 VRRFGLIGYLNKFISPPIVYGTLLIIIGAQLADIGLKNWF-GSADTGINFAASXXXXXXX 183 +R I ++KFI P IV GT+++I+G L + + N F + IN + Sbjct: 122 LRFLSKI--ISKFI-PHIVGGTVIVIVGISLMPVAMTNIFTAPGNLKINCILALISSALL 178 Query: 184 XXXXXFGGNT-----ILRRGALLWGIIAGTIFYSIFGTTNFSSVAAAGWFSFPDVFPFGF 238 G + +R +++ +I GTI S+ G +F+ V A WFSFP + PFG Sbjct: 179 VGCMMIGRKSNKFGKAVRLTSVMISLIGGTIAASLLGVVDFTPVTKAAWFSFPKLLPFGK 238 Query: 239 GV-SVPIVILMLLAFLQASAEAVGMYTLLTKWGNQKLDNDRVNRGLFGEFLGSTLGAVFG 297 V + ++ ML + E G + ++ +L ++ +NRG GE +G +GA+FG Sbjct: 239 PVFDLKAILTMLFIYAVILVETSGTWFAVSAVTGSELTDEGLNRGAVGEGIGCFVGALFG 298 Query: 298 GLGTTSYPENIGIVRVSGIGSRYVTMTAGVLAIVLGLIPKVGMFIASLPGPVLSAASTIL 357 G T Y N GI+ V+G+GSR + G++ + LG++PK+ IA +P V+S ++ Sbjct: 299 GTPMTGYSTNAGIIAVTGVGSRMAIIAGGIILVALGMLPKLMNVIACIPSAVVSGVFAVV 358 Query: 358 FGIIAISGIQMVSKVVWDELNLVVAGSSFIISLGTMYLPAELTQNLP 404 IIA++G + + +DE N+++ G +++LGT LP ++ +LP Sbjct: 359 CVIIAMNGFKSIQHEEFDERNMLLIGLPILLALGTTVLPKDILNSLP 405 >C3KYW4.1 C3KYW4_CLOB6 Xanthine/uracil permease family protein Length = 447 Score = 204 bits (520), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 134/411 (32%), Positives = 219/411 (53%), Gaps = 13/411 (3%) Query: 1 MHSTHSEEQVLTVGIEEKLSIGANVTYGFQHLLALTGIFLFPVLIGQALGLDASIIGYMI 60 M ST L VGI+EK+S+ G QH+ A+ +++ P+++ L LDA Y I Sbjct: 1 MKSTKDTN--LIVGIDEKISLRYAFFLGLQHVFAMD-LYIVPIILAGILSLDAQNTAYFI 57 Query: 61 QACFLTTGIVTVLQSGKMLRLPVVQGPTAAFFVAVLSAGSTVGLGTAFGSMAVAGLIFML 120 Q F+ GI T++Q+G +RLP++QGP+ A+ + GS +GL GS+ L M+ Sbjct: 58 QMSFIAAGIATLIQTGLCMRLPIMQGPSYIPIGALAAIGSKLGLQAMVGSLIPGSLFLMI 117 Query: 121 LSIPVRRFGLIGYLNKFISPPIVYGTLLIIIGAQLADIGLKNWF-GSADTGINFAASXXX 179 L P+R I ++KFI P IV GT++II+G L + + N F + IN + Sbjct: 118 LGYPLRFLSKI--ISKFI-PHIVGGTVIIIVGISLMPVAMTNIFTAPGNLKINCILALIS 174 Query: 180 XXXXXXXXXFGGNT-----ILRRGALLWGIIAGTIFYSIFGTTNFSSVAAAGWFSFPDVF 234 G + +R +++ +I GTI S+ G +F+ V A WFSFP + Sbjct: 175 SALLVSCMMIGRKSNKFGKAVRLTSVMISLIGGTIAASLLGVVDFTPVTKAAWFSFPKLL 234 Query: 235 PFGFGV-SVPIVILMLLAFLQASAEAVGMYTLLTKWGNQKLDNDRVNRGLFGEFLGSTLG 293 PFG V + ++ ML + E G + ++ +L ++ +NRG GE +G +G Sbjct: 235 PFGKPVFDLKAILTMLFIYAVILVETSGTWFAVSAVTGSELTDEGLNRGAVGEGIGCFVG 294 Query: 294 AVFGGLGTTSYPENIGIVRVSGIGSRYVTMTAGVLAIVLGLIPKVGMFIASLPGPVLSAA 353 A+FGG T Y N GI+ V+G+GSR + G++ + LG++PK+ IA +P V+S Sbjct: 295 ALFGGTPMTGYSTNAGIIAVTGVGSRMAIIAGGIILVALGMLPKLMNVIACIPSAVVSGV 354 Query: 354 STILFGIIAISGIQMVSKVVWDELNLVVAGSSFIISLGTMYLPAELTQNLP 404 ++ IIA++G + + DE N+++ G +++LGT LP ++ +LP Sbjct: 355 FAVVCVIIAMNGFKSIQHEELDERNMLLIGLPILLALGTTVLPKDILNSLP 405 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.325 0.141 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,377,233,086 Number of extensions: 99420965 Number of successful extensions: 429730 Number of sequences better than 1.0e-05: 2720 Number of HSP's gapped: 423512 Number of HSP's successfully gapped: 2773 Length of query: 453 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 314 Effective length of database: 1,751,175,118 Effective search space: 549868987052 Effective search space used: 549868987052 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 133 (55.8 bits)