BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0591.0012.p (381 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1D917.1 B1D917_9BACL Two component transcriptional regulator, A... 248 7e-64 B3KEX5.1 B3KEX5_9BACI Response regulator receiver 199 6e-49 C4ZHX9.1 C4ZHX9_9FIRM Two-component response regulator 197 1e-48 C0Z9S9.1 C0Z9S9_BREBN Probable two-component response regulator 175 6e-42 B1DAE3.1 B1DAE3_9BACL Two component transcriptional regulator, A... 158 8e-37 >B1D917.1 B1D917_9BACL Two component transcriptional regulator, AraC family Length = 361 Score = 248 bits (633), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 138/380 (36%), Positives = 212/380 (55%), Gaps = 24/380 (6%) Query: 1 MIKVLIVDDDNLVRKGLRSMLPWLEYNMEVVGEAKNGEKALDFLAEQQVDLLLTDLAMPV 60 MI+VLIVDDD L RKG S++PW ++M VVGEA NG KAL+F+ + +VDL+ DL+MPV Sbjct: 1 MIRVLIVDDDKLARKGFISIMPWSNHDMVVVGEAANGAKALEFMEQHEVDLMFVDLSMPV 60 Query: 61 MSGMELMRVVRRQYPRISIVVLTLHQDFEYIQDCLRLGAIDYIAKVELETDSYDEVMGRI 120 MSGMEL++V R+++P + V+L+ H++FE +Q R+G +DYI+KV LE++ ++++ RI Sbjct: 61 MSGMELLQVTRQRFPGLRSVILSFHEEFENVQTAYRMGVLDYISKVRLESEDDEQILKRI 120 Query: 121 SARIQEEKMKNAAPVNLTAEAVSGNNSFYTVIPGQMPTNEVIRDTASLSMPTVSMDLLTG 180 + +M AA + + S N P P +V T + +G Sbjct: 121 -----QLQMTGAATQQPSGQPPSALN------PAHAPEQDV---------RTQEEEGWSG 160 Query: 181 LKKSGQSLGWVHKESEFVRFLESLKGAALPPARLTGFLNTLLPGWNRIYASVTGQQIELP 240 L++ ++ W++ ES F R + A + RL G +L + G Q EL Sbjct: 161 LEREWRANYWLYNESVFQRLCKQTAQAKVSFRRLEGLFMRVLSQLE----TDLGLQAELG 216 Query: 241 ETFVAWFEVEEWLNNTRQSLAAAIGKPQYSEEVKECIARAVQAMHEEMANPVIASEMAKR 300 EW+ + R+ + A + I +AV + E+ + + A +A Sbjct: 217 SDAADVRSAVEWMRDFRKRVYAQVAATTDFTNTTTSILKAVLFIREQASGTLHAEGVADH 276 Query: 301 VNMSRSYFSQCFKDMVGMTFNDYLRTIRMDKAKEYLQYTQKNMQWISEHTGYTDQKYFSR 360 V+MSRSYFSQCFK + G TFNDYL+ R+ A+ L T +++ W++ GY D KYFS+ Sbjct: 277 VHMSRSYFSQCFKRLTGSTFNDYLKQERIRSAERLLCETNQSIAWVAHAVGYNDSKYFSQ 336 Query: 361 VFYEKTGMLPSEYRQSVQAG 380 +FYE+T +LPSE+R G Sbjct: 337 LFYEQTRLLPSEFRAQFIGG 356 >B3KEX5.1 B3KEX5_9BACI Response regulator receiver Length = 474 Score = 199 bits (505), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 101/169 (59%), Positives = 124/169 (73%), Gaps = 1/169 (0%) Query: 1 MIKVLIVDDDNLVRKGLRSMLPWLEYNMEVVGEAKNGEKALDFLAEQQVDLLLTDLAMPV 60 MI VLIVDDD LVRKGL S LPW + M VVGEA NGEKALDFL +VDLL+TDLAMPV Sbjct: 1 MIHVLIVDDDKLVRKGLMSFLPWESFGMRVVGEAANGEKALDFLKANRVDLLMTDLAMPV 60 Query: 61 MSGMELMRVVRRQYPRISIVVLTLHQDFEYIQDCLRLGAIDYIAKVELETDSYDEVMGRI 120 MSG+EL+RVVR+QYP I+I VLTLHQDFEYIQ+ LRLGAIDYIAKVELE + ++EV RI Sbjct: 61 MSGIELIRVVRKQYPNIAIAVLTLHQDFEYIQEALRLGAIDYIAKVELEKEQFEEVFQRI 120 Query: 121 SARIQEEKMKNAAPVNLTAEAVSGNNSFYTVI-PGQMPTNEVIRDTASL 168 +RI+E K K+ + A + ++ + P + T+ ++ D SL Sbjct: 121 HSRIEEVKQKHKNESDSIVAACPCDTAYALLTYPDEPLTSRMVADCVSL 169 Score = 193 bits (490), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 88/199 (44%), Positives = 131/199 (65%) Query: 181 LKKSGQSLGWVHKESEFVRFLESLKGAALPPARLTGFLNTLLPGWNRIYASVTGQQIELP 240 +K+ + WVH + F + LK +P ++L ++ + WNR+Y ++ I++P Sbjct: 275 VKELLHAFTWVHDDEAFDKLCSRLKELRIPVSKLMQWIYGCMVDWNRLYRAIQPDDIKMP 334 Query: 241 ETFVAWFEVEEWLNNTRQSLAAAIGKPQYSEEVKECIARAVQAMHEEMANPVIASEMAKR 300 +TF W EV +WL R++ G Q S EV I AV+ +H+E+ P+ A ++AKR Sbjct: 335 DTFTCWREVADWLKQFRENGMTLSGSLQLSPEVSGSIMTAVKIVHDELELPLFAIDVAKR 394 Query: 301 VNMSRSYFSQCFKDMVGMTFNDYLRTIRMDKAKEYLQYTQKNMQWISEHTGYTDQKYFSR 360 VN+SRSYF QCFK++VG +FN+YLR +R+DKA+EYL+ T + + WI++ TGY D+KYFSR Sbjct: 395 VNLSRSYFYQCFKEIVGYSFNEYLRKVRIDKAREYLEQTARPIVWIAKQTGYEDEKYFSR 454 Query: 361 VFYEKTGMLPSEYRQSVQA 379 F E+TGMLPSEYRQ +A Sbjct: 455 TFREQTGMLPSEYRQRYKA 473 >C4ZHX9.1 C4ZHX9_9FIRM Two-component response regulator Length = 336 Score = 197 bits (501), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 116/378 (30%), Positives = 199/378 (52%), Gaps = 57/378 (15%) Query: 2 IKVLIVDDDNLVRKGLRSMLPWLEYNMEVVGEAKNGEKALDFLAEQQVDLLLTDLAMPVM 61 +KVL+VDDD L RKGL S++ W +Y EVVG+ +NG KAL+FL + +VD++ TD+ MP + Sbjct: 1 MKVLVVDDDKLARKGLISIMDWKKYGFEVVGDVQNGRKALEFLKDNEVDIVFTDIDMPEI 60 Query: 62 SGMELMRVVRRQYPRISIVVLTLHQDFEYIQDCLRLGAIDYIAKVELETDSYDEVMGRIS 121 G+ELM++ +++YP + VV ++++DF Y Q LRLGA+DYI+K+ E D D ++ + Sbjct: 61 DGIELMKMCKKEYPEVKFVVFSMYEDFRYAQSALRLGALDYISKISFEGDECDRILELVE 120 Query: 122 ARIQEEKMKNAAPVNLTAEAVSGNNSFYTVIPGQMPTNEVIRDTASLSMPTVSMDLLTGL 181 + +E N + + +S +L+ L Sbjct: 121 RKYKE---------NHSQKETRNEDS----------------------------ELIKRL 143 Query: 182 KKSGQSLGWVHKESEFVRFLESLKGAALPPARLTGFLNTLLPGWNRIYASVTGQQIELP- 240 +K+ + W+ +SEF R E +G L A + ++ + +TG+++E P Sbjct: 144 EKAWMNTRWIFNDSEFNRLYELTRGVELRTAE-----RVFIKSFHSL-QKLTGEELEFPS 197 Query: 241 ----ETFVAWFEVEEWLNNTRQS-LAAAIGKPQYSEEVKECIARAVQAMHEEMANPVIAS 295 ++ + W V++W N Q+ L K Y AR + E + + + Sbjct: 198 LSSVDSMLEW--VKQWKENLYQTCLQTDKTKDIY------MFARVILYTDEHIEENLKSE 249 Query: 296 EMAKRVNMSRSYFSQCFKDMVGMTFNDYLRTIRMDKAKEYLQYTQKNMQWISEHTGYTDQ 355 E A ++ MSRSYFS FK+M G TF++Y+ + +M A + + +N+ I+ + GY + Sbjct: 250 EAAAQIGMSRSYFSTRFKEMTGDTFHNYVISRKMYAAAQKMAKGTENITQIASNLGYDNF 309 Query: 356 KYFSRVFYEKTGMLPSEY 373 YF++VF ++ G +P+EY Sbjct: 310 YYFTKVFSKEYGCMPTEY 327 >C0Z9S9.1 C0Z9S9_BREBN Probable two-component response regulator Length = 397 Score = 175 bits (444), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 120/393 (30%), Positives = 196/393 (49%), Gaps = 36/393 (9%) Query: 2 IKVLIVDDDNLVRKGLRSMLPWLEYNMEVVGEAKNGEKALDFLAEQQVDLLLTDLAMPVM 61 IKV+IVDD+ LVR+GL++M+PW Y MEVV +A NG K + + Q +L++TD+ MP M Sbjct: 3 IKVMIVDDEVLVRRGLKAMVPWSRYGMEVVADAPNGRKGWEAFLQIQPELVITDIVMPEM 62 Query: 62 SGMELMRVVRRQYPRISIVVLTLHQDFEYIQDCLRLGAIDYIAKVELETDSYDEVMGRIS 121 G+EL R V+ P+ +++L+ H+DF + Q + LG Y+ K E + + + ++ ++ Sbjct: 63 DGLELCRRVKEHAPQTKVLLLSCHRDFSFAQQGISLGVSGYLLKTEFQDEEWGTLLEKLR 122 Query: 122 ARIQEEKMKNAAPVNLTAEAVSGNNSFYTVIPG-----QMPTNEVIRDTASLSMPTVSMD 176 + E +A P N+ F + G + + +++ S ++ + Sbjct: 123 TELAGE---SARPENVRERPDEWKREFGAWLTGLSRDFEQSLSSLLQSHWSWMNDSMRVW 179 Query: 177 LLTGLKKSG---QSLGWVHK--ESEF-------VRFLESLKGAALPPARLTGFLNTLLPG 224 LL G+ + Q WV ESE+ +RFL L PA + +LL Sbjct: 180 LLEGMGSANQEEQERAWVASELESEWEWLACGDIRFL-------LTPASTGRQVESLLVE 232 Query: 225 WNRIYASVTGQQIELPETFVAWFEVEEWLNNTRQSLAAAIGKPQYS---EEVKECIARAV 281 W ++ VT + P F +E W+ R +Y + +E I +AV Sbjct: 233 W-KLAGKVTSWETASP--FAG---LESWIQTVRMLYQRTQRARKYGVIQDPWQEPIKQAV 286 Query: 282 QAMHEEMANPVIASEMAKRVNMSRSYFSQCFKDMVGMTFNDYLRTIRMDKAKEYLQYTQK 341 + + P+ SE+A +V +SRS+FS FK VG +F ++L R+ A+ L T Sbjct: 287 HYALDRLDTPLTVSEVASQVGLSRSHFSVMFKKGVGESFGEFLDKRRVKMAQAMLNETAL 346 Query: 342 NMQWISEHTGYTDQKYFSRVFYEKTGMLPSEYR 374 ++Q ++E G D KYFS+ F + TGM PS YR Sbjct: 347 SIQEVAERVGLPDPKYFSKWFKKYTGMTPSHYR 379 >B1DAE3.1 B1DAE3_9BACL Two component transcriptional regulator, AraC family Length = 397 Score = 158 bits (400), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 117/398 (29%), Positives = 203/398 (51%), Gaps = 33/398 (8%) Query: 3 KVLIVDDDNLVRKGLRSMLPWLEYNMEVVGEAKNGEKALDFLAEQQVDLLLTDLAMPVMS 62 KVLI DD++++R+G+RS +PW + +EVVGEA++GE+AL+ E+Q ++LL DL+MP+M+ Sbjct: 6 KVLIADDESIIREGIRSSIPWEDLQLEVVGEAEDGEEALELAVEKQANILLVDLSMPIMN 65 Query: 63 GMELMRVVRRQYPRISIVVLTLHQDFEYIQDCLRLGAIDYIAKVELETDSYDEVMGRISA 122 G+ L+ +R+Q P+ IV++T H +F Y + ++L DYI K + D EV+ R+ Sbjct: 66 GLTLISHLRQQLPKCKIVIITGHDEFNYAYEAIKLEVDDYILK-PVNPDMLGEVLARVVQ 124 Query: 123 RIQEEKMKNAAPVNLTAEAVSGNNSFYTV------IPGQMPTNEVIRDTASLSMPTVSMD 176 ++ EE N + + ++ + N + I G++ E+ + L MP D Sbjct: 125 KL-EETTVNEELLQMASKQIDKNFALLRERFCLEWIKGELGEAEIREQLSFLRMPGEEPD 183 Query: 177 LLTGLKKSGQSLG---WVHKESEFVRF-LESLKGAALPP------ARLTGFLNTLLPG-- 224 + ++ QS G + K+ + + F +E++ L P G + L+ G Sbjct: 184 YVGVIRWPEQSKGKAFFSEKDRQLLLFAIENIMEEHLEPFTSVHFRDKVGLIVVLIWGKP 243 Query: 225 ----WNRIYASVTGQ-QIELPETF--VAWFEVEEWLNNTRQSLAAAIGKPQYSEEVKECI 277 + +I A V G +IE+ ++ + +V R S+ + KE I Sbjct: 244 QESVFRQIEADVAGYLKIEIVASYQHSSSGDVPSLYAEARASVNRETKLSPFVRRTKEII 303 Query: 278 ARAVQAMHEEMANPVIASEMAKRVNMSRSYFSQCFKDMVGMTFNDYLRTIRMDKAKEYLQ 337 + + +++ IA E+ N+S Y S+ FK +G +F L RM +A L Sbjct: 304 SDRFE--DRDLSLEGIAGEL----NVSAVYLSRIFKQEMGTSFISMLTAARMKEAIRLLN 357 Query: 338 YTQKNMQWISEHTGYTDQKYFSRVFYEKTGMLPSEYRQ 375 T + + I+E TGY Q YFS F + TG+ P++YR+ Sbjct: 358 ETDQAIHEIAEKTGYESQHYFSTAFKKTTGLPPNQYRK 395 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.132 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,110,195,843 Number of extensions: 80469281 Number of successful extensions: 319221 Number of sequences better than 1.0e-05: 12509 Number of HSP's gapped: 330787 Number of HSP's successfully gapped: 13033 Length of query: 381 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 244 Effective length of database: 1,770,017,148 Effective search space: 431884184112 Effective search space used: 431884184112 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 132 (55.5 bits)