BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0591.0006.p (413 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A6BKM7.1 A6BKM7_9FIRM Putative uncharacterized protein 282 5e-74 B8I2M0.1 B8I2M0_CLOCE Major facilitator superfamily MFS_1 281 9e-74 C0FL29.1 C0FL29_9CLOT Putative uncharacterized protein 280 2e-73 A9KJ69.1 A9KJ69_CLOPH Major facilitator superfamily MFS_1 278 7e-73 C4IBW0.1 C4IBW0_CLOBU Major facilitator superfamily protein 277 1e-72 >A6BKM7.1 A6BKM7_9FIRM Putative uncharacterized protein Length = 393 Score = 282 bits (721), Expect = 5e-74, Method: Compositional matrix adjust. Identities = 150/387 (38%), Positives = 229/387 (59%), Gaps = 11/387 (2%) Query: 15 MATLLLVVIYIIFISLGIPDSLFGAAWPAIYDEFSLPVSAAGSVTFTISACTTISSLLSA 74 M LLL VIY+ FISLG+PD+L G+AWP++Y F +PVS AG ++ I+A T ISSL S Sbjct: 1 MFHLLLSVIYLAFISLGLPDALLGSAWPSMYPAFHVPVSYAGIISMIIAAGTVISSLQSD 60 Query: 75 RLINKYGTAKLTTISVFLTATALLGFSLSPNIIWFCXXXXXXXXXXXXXXXXXNNYVALY 134 RL K GT K+T ISV TA AL GFS+S + I C NNYVAL+ Sbjct: 61 RLTKKLGTGKITAISVATTAVALFGFSVSHSFIALCLWAVPYGLGGGSVDAALNNYVALH 120 Query: 135 YKASHMNLLHCFYGLGVSVSPYIMSLALSQQNNWRGGYSNAFWIQXXXXIALIALCSLPL 194 Y++ HM+ LHC +G+G S+ PYIM ALS + W GY Q LI SLPL Sbjct: 121 YESRHMSWLHCMWGVGASIGPYIMGYALSNKQGWSMGYRYISIFQIGLTAILI--ISLPL 178 Query: 195 WKKVNRHKQ-----EAEDEVFHIVSITTLFKLPSARAVFFILISSCAIEYTAGIWGSTFL 249 WK+ ++ + ++++ +F++P AR + F A+E T+ +W S++L Sbjct: 179 WKQFHKKEHIGQSASGSGNTLPVLTLKQIFQIPGAREILFAFFCYSAVEQTSSLWASSYL 238 Query: 250 VNTKGLTAENAAKCLALYYIXXXXXXXXXXXXXXXXSSWKLIYIGQSVLITAIFMLMLPL 309 V G ++E AA +L++I + ++I++G+ +++ + ++LPL Sbjct: 239 VLHLGYSSEKAAGFASLFFIGITVGRGISGFITFKLNDSQMIHLGEGIILLGVLAMLLPL 298 Query: 310 PTSVSVGALLLIGLGNAPIFPNILHLTPQNFGKEYSQSMMGAQMAVSXXXXXVGIALMPP 369 +V++ L+LIGLG API+P+I+H TP +FG + SQ+++G QMA + +G LMPP Sbjct: 299 GKTVALAGLILIGLGCAPIYPSIIHSTPAHFGADKSQAIIGVQMAFA----YIGTCLMPP 354 Query: 370 LYGILAQKLSMSIFPYFIVLLFCMMLF 396 L+GI+A+ +S+++FP ++ L C+M F Sbjct: 355 LFGIIARSISITLFPAYLGLFLCIMFF 381 >B8I2M0.1 B8I2M0_CLOCE Major facilitator superfamily MFS_1 Length = 388 Score = 281 bits (719), Expect = 9e-74, Method: Compositional matrix adjust. Identities = 161/400 (40%), Positives = 238/400 (59%), Gaps = 15/400 (3%) Query: 15 MATLLLVVIYIIFISLGIPDSLFGAAWPAIYDEFSLPVSAAGSVTFTISACTTISSLLSA 74 M TLLL++IYI FISLG+PDS+ GAAWP + + S+P++ AG ++ IS T ISS+LS Sbjct: 1 MTTLLLIIIYIAFISLGLPDSMLGAAWPTVRTDLSVPMAGAGLISMIISGGTIISSILSG 60 Query: 75 RLINKYGTAKLTTISVFLTATALLGFSLSPNIIWFCXXXXXXXXXXXXXXXXXNNYVALY 134 +LI K+GT KLT +SVF+TA ALLGFS S N IW C NN+VAL+ Sbjct: 61 KLIQKFGTGKLTLMSVFMTAMALLGFSFSQNYIWLCLVAIPLGLGAGAVDAALNNFVALH 120 Query: 135 YKASHMNLLHCFYGLGVSVSPYIMSLALSQQNNWRGGYSNAFWIQXXXXIALIALCSLPL 194 + A HM+ LHCF+G+G + P IMS+A+ Q +W+ GY + IQ I I L SLPL Sbjct: 121 FSARHMSWLHCFWGIGATAGPVIMSVAIIQNGSWQKGYLSVAIIQICLVI--ILLFSLPL 178 Query: 195 WKKVNRHKQE---AEDEVFHIVSITTLFKLPSARAVFFILISSCAIEYTAGIWGSTFLVN 251 W+ ++QE E++ H+ F+LP CA+E TAG+WG+++LV Sbjct: 179 WRLFGENRQEDIAVENQNQHV------FRLPGIPPALLSFFCYCALETTAGLWGASYLVQ 232 Query: 252 TKGLTAENAAKCLALYYIXXXXXXXXXXXXXXXXSSWKLIYIGQSVLITAIFMLMLPLPT 311 TKG++A+ AA +++YY+ S+ LI GQ ++ +L++ T Sbjct: 233 TKGVSADVAAGWISMYYLGITLGRLVNGFITTKWSNPALIRGGQIIIGIGAILLLISNQT 292 Query: 312 SVSVGALLLIGLGNAPIFPNILHLTPQNFGKEYSQSMMGAQMAVSXXXXXVGIALMPPLY 371 V++ L+LIG+G APIFP++LH TP FGK S+ +MG QMAV+ +G L+PP Sbjct: 293 YVNLLGLILIGMGCAPIFPSMLHETPVRFGKNNSEKLMGVQMAVA----YMGTTLVPPAI 348 Query: 372 GILAQKLSMSIFPYFIVLLFCMMLFSIYRLRATLKEQQIK 411 G+L+ + + +P FI++L +ML S ++ + + +K Sbjct: 349 GVLSGVVGIQFYPIFILVLLIVMLVSSEKINKIVTRRTLK 388 >C0FL29.1 C0FL29_9CLOT Putative uncharacterized protein Length = 396 Score = 280 bits (715), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 164/401 (40%), Positives = 230/401 (57%), Gaps = 17/401 (4%) Query: 15 MATLLLVVIYIIFISLGIPDSLFGAAWPAIYDEFSLPVSAAGSVTFTISACTTISSLLSA 74 M LLL VIY+ FISLG+PDSL G+AWP++Y EF +PVS+A + ISA T +SSLLS Sbjct: 1 MFHLLLAVIYLSFISLGLPDSLLGSAWPSMYPEFGVPVSSASIIFMIISAGTIVSSLLSD 60 Query: 75 RLINKYGTAKLTTISVFLTATALLGFSLSPNIIWFCXXXXXXXXXXXXXXXXXNNYVALY 134 RL GT K+T+ SV LTA +L GFSLS + C NNYVAL+ Sbjct: 61 RLTRCLGTGKVTSFSVGLTALSLFGFSLSHSFWLLCLFAVPYGLGAGSVDAALNNYVALH 120 Query: 135 YKASHMNLLHCFYGLGVSVSPYIMSLALSQQNNWRGGYSNAFWIQXXXXIALIALCSLPL 194 YK+ HM+ LHC +G+G S+ P IM LALS + W GY +Q L L SLPL Sbjct: 121 YKSRHMSWLHCMWGVGASLGPCIMGLALSDGHPWNTGYLCISLLQAALTAVL--LVSLPL 178 Query: 195 WKKVNRHKQEAEDE---VFHIVSITTLFKLPSARAVFFILISSCAIEYTAGIWGSTFLVN 251 W K KQ A D +S + ++P AR + CA+E TAG+WGS+FLV Sbjct: 179 WGK----KQTAADNDASQGQPLSFREVIRIPGAREIMVTFFCYCALEQTAGLWGSSFLVL 234 Query: 252 TKGLTAENAAKCLALYYIXXXXXXXXXXXXXXXXSSWKLIYIGQSVLITAIFMLMLPLPT 311 +G++ E+AA+ +L+++ S L+ +GQ +++ I L LP Sbjct: 235 HRGVSPEDAARFASLFFLGITAGRAAGGFLTMLLSDTNLVRLGQGIILVGILALFLPAGG 294 Query: 312 SVSVGALLLIGLGNAPIFPNILHLTPQNFGKEYSQSMMGAQMAVSXXXXXVGIALMPPLY 371 S+ LLLIGLG AP++P+I+H TP+ FG E SQ+++G QMA + VG LMPPL+ Sbjct: 295 FFSMAGLLLIGLGCAPVYPSIIHSTPERFGAENSQAVIGIQMASA----YVGNCLMPPLF 350 Query: 372 GILAQKLSMSIF-PYFIVLLFCMMLF---SIYRLRATLKEQ 408 G++A+ L + +F PY +++L M L ++ + R E+ Sbjct: 351 GLIAEHLDIGLFIPYLLLILAAMFLMHEKTVRKCRMACMER 391 >A9KJ69.1 A9KJ69_CLOPH Major facilitator superfamily MFS_1 Length = 386 Score = 278 bits (711), Expect = 7e-73, Method: Compositional matrix adjust. Identities = 151/388 (38%), Positives = 229/388 (59%), Gaps = 7/388 (1%) Query: 15 MATLLLVVIYIIFISLGIPDSLFGAAWPAIYDEFSLPVSAAGSVTFTISACTTISSLLSA 74 M ++LLVVIY+ FISLG+PDS+ G+AWP++Y + + S+AG ++ I+ T +SSL+S Sbjct: 1 MISILLVVIYVAFISLGLPDSILGSAWPSMYQDLHVSFSSAGMISMIIAGGTIVSSLVSD 60 Query: 75 RLINKYGTAKLTTISVFLTATALLGFSLSPNIIWFCXXXXXXXXXXXXXXXXXNNYVALY 134 R++ K+ T +TT+SV +TA ALLGFS S + C NN+VAL+ Sbjct: 61 RMLRKFSTGIITTVSVAITAVALLGFSFSNSFWQLCLWSIPYGLGAGSVDAALNNFVALH 120 Query: 135 YKASHMNLLHCFYGLGVSVSPYIMSLALSQQNNWRGGYSNAFWIQXXXXIALIALCSLPL 194 YK+ HM+ LHCF+G+G ++ PYIM L L+ W GY IQ I L SLPL Sbjct: 121 YKSRHMSWLHCFWGVGATLGPYIMGLCLTNGLKWNSGYQTIGVIQIILVIFL--FISLPL 178 Query: 195 WKKVNRHKQEAEDEVFHIVSITTLFKLPSARAVFFILISSCAIEYTAGIWGSTFLVNTKG 254 W KV +E E ++ KLP A+ + S A+E TAG+W S+F+V KG Sbjct: 179 W-KVKHIDKENEVVEAKGLNFRETVKLPGAKPILIAFFSYSALEATAGLWASSFMVLYKG 237 Query: 255 LTAENAAKCLALYYIXXXXXXXXXXXXXXXXSSWKLIYIGQSVLITAIFMLMLPLPTSVS 314 + A AAK AL+Y+ + K+I +GQ++ M++LPL + Sbjct: 238 IDAVTAAKWAALFYLGITVGRFLAGFVTGKLGNKKMIRLGQAIAFLGTIMMLLPLGNLGA 297 Query: 315 VGALLLIGLGNAPIFPNILHLTPQNFGKEYSQSMMGAQMAVSXXXXXVGIALMPPLYGIL 374 + L+LIGLG API+P++LH TP NFG + SQS+MG QMA + +G +M PL+G++ Sbjct: 298 LFGLILIGLGCAPIYPSLLHETPDNFGADKSQSIMGMQMACA----YIGTTIMAPLFGVI 353 Query: 375 AQKLSMSIFPYFIVLLFCMMLFSIYRLR 402 A+K+S+S++P+++++ +M + R+ Sbjct: 354 AEKISISVYPFYLMIFTVLMFVMVERVN 381 >C4IBW0.1 C4IBW0_CLOBU Major facilitator superfamily protein Length = 386 Score = 277 bits (709), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 158/397 (39%), Positives = 230/397 (57%), Gaps = 12/397 (3%) Query: 15 MATLLLVVIYIIFISLGIPDSLFGAAWPAIYDEFSLPVSAAGSVTFTISACTTISSLLSA 74 M LLL VIY+ FISLG+PDSL G+AWPA+Y EF +PVS AG ++ I+A T +SSL S Sbjct: 1 MIHLLLAVIYLSFISLGLPDSLLGSAWPAMYGEFGVPVSYAGIISMIIAAGTILSSLQSD 60 Query: 75 RLINKYGTAKLTTISVFLTATALLGFSLSPNIIWFCXXXXXXXXXXXXXXXXXNNYVALY 134 RL K GT K+T ISV +TA AL GFS S + C NNYVAL Sbjct: 61 RLTRKLGTGKVTAISVAMTAVALFGFSFSNSFWILCFWAIPYGLGAGSVDSSLNNYVALN 120 Query: 135 YKASHMNLLHCFYGLGVSVSPYIMSLALSQQNNWRGGYSNAFWIQXXXXIALIALCSLPL 194 Y + HM+ LHC +G+G S+ PYIM A++ W GY +Q I LI SLPL Sbjct: 121 YASRHMSWLHCMWGVGASLGPYIMGYAMTGGQGWNSGYGYIAVLQIVLTIILI--FSLPL 178 Query: 195 WKKVNRHKQEAEDEV-FHIVSITTLFKLPSARAVFFILISSCAIEYTAGIWGSTFLVNTK 253 WK NR +++ D+V +++ + K+ A+ + CA+E T G+W S++L K Sbjct: 179 WK--NRAEEKNADDVNAKTLTLKEIIKISGAKEIMITFFCYCALEQTTGLWASSYLTLHK 236 Query: 254 GLTAENAAKCLALYYIXXXXXXXXXXXXXXXXSSWKLIYIGQSVLITAIFMLMLPLPTSV 313 G++A+ AA ++++I S K+I GQ V I LMLP + Sbjct: 237 GISADKAASFASMFFIGITIGRAFSGFITMKLSDSKMIRFGQGVAAIGIITLMLPFGEYI 296 Query: 314 SVGALLLIGLGNAPIFPNILHLTPQNFGKEYSQSMMGAQMAVSXXXXXVGIALMPPLYGI 373 S+ L++IGLG API+P I+H TP+ FG + SQ+++G QMA + +G LMPP++G+ Sbjct: 297 SLIGLIMIGLGCAPIYPCIIHSTPEYFGADKSQAIIGVQMASA----YIGTLLMPPIFGL 352 Query: 374 LAQKLSMSIFPYFIVLLFCMMLFSIYRLRATLKEQQI 410 +A+ +++S++P V LF +M+F + A L+++ I Sbjct: 353 IAEYINVSLYP---VYLFIVMIFMVVMHEALLRKKNI 386 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.327 0.139 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,012,067,276 Number of extensions: 68034572 Number of successful extensions: 237160 Number of sequences better than 1.0e-05: 77 Number of HSP's gapped: 236920 Number of HSP's successfully gapped: 85 Length of query: 413 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 275 Effective length of database: 1,760,596,133 Effective search space: 484163936575 Effective search space used: 484163936575 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 132 (55.5 bits)