BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0587.0018.p (443 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C3HA00.1 C3HA00_BACTU Phenylalanine racemase 318 9e-85 C3H9Z8.1 C3H9Z8_BACTU Glutamate racemase 300 2e-79 Q9R9J0.1 MYCB_BACSU Mycosubtilin synthetase subunit B ATP-depend... 298 9e-79 Q93I55.1 Q93I55_BACSU Iturin A synthetase B 295 6e-78 B3TLA2.1 B3TLA2_BACSU Iturin A synthetase B 293 2e-77 >C3HA00.1 C3HA00_BACTU Phenylalanine racemase Length = 6350 Score = 318 bits (814), Expect = 9e-85, Method: Compositional matrix adjust. Identities = 170/429 (39%), Positives = 259/429 (60%), Gaps = 8/429 (1%) Query: 8 KQETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLR 67 +++ YYP S AQR +++ +K+ G G +YN+P +IKG LD +LE KL+ RHE+LR Sbjct: 1038 EEQDYYPLSSAQRRLYILNKIEGSGVSYNMPFAMKIKGDLDVHQLENTFYKLIERHEALR 1097 Query: 68 TTIELDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRL 127 T+ + G QKI + F E+ + +I FV+PF L+K PL R +I + Sbjct: 1098 TSFVMV--DGEPVQKIEKEIDFQVTYREMGTNKLDEMINGFVKPFDLEKGPLLRVEIIHV 1155 Query: 128 TDREETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQ 187 TD +E V+++DMHHII+DG S++IL ++L LYE +EL L LQYKDYAV Q L E+ Sbjct: 1156 TD-DEHVMVLDMHHIISDGVSMNILNRELCKLYEGKELSPLDLQYKDYAVWQKDLFTQEE 1214 Query: 188 WNRQEEYWLGVFHEPVPAL--PWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTE 245 +QEEYW+ VF E VP L P D + ++ E R+ F ID + L+R+A+ Sbjct: 1215 MKKQEEYWINVFKEEVPILNMPTDYKRPPTQSVEGARRS--FEIDSELTKNLNRIAKENG 1272 Query: 246 STLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLS 305 T++M+L+A +T LLS+ + +DIVVG P +GR H +NIVGM VNTLA+R + + Sbjct: 1273 VTMYMLLLAGYTTLLSRYTGQDDIVVGSPIAGRSHHDFENIVGMFVNTLAMRNYPNEDKT 1332 Query: 306 FQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAA-EQIDA 364 F+ YL +VK+ ++AYENQDYPLD LVEKL+ ++ LF+ MF ++ + E+I Sbjct: 1333 FRNYLREVKENALKAYENQDYPLDELVEKLDLQRDMSRSALFDTMFVLQNLDTSNEEIKG 1392 Query: 365 IDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITS 424 + ++ + FDL V+ ++ + ++ Y LF +E I ++ F+ I++ IT+ Sbjct: 1393 LSFETYDSELNIANFDLTLSAVETNNIIKFDLEYCTKLFKKETIAKISEHFVSILREITN 1452 Query: 425 NLETGLGDL 433 N E LG + Sbjct: 1453 NQEVCLGQI 1461 Score = 303 bits (775), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 165/430 (38%), Positives = 250/430 (58%), Gaps = 8/430 (1%) Query: 8 KQETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLR 67 +++ YYP S AQ+ +++ +K+ G G +YN+P +IKG LD +LE+A KL+ RHE+LR Sbjct: 3575 EEQDYYPLSSAQKRLYILNKIEGNGVSYNIPFAMKIKGDLDVQQLEKAFHKLIERHEALR 3634 Query: 68 TTIELDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRL 127 T+ + G QKI + F E+ + +I FV+PF L+K PL R +I + Sbjct: 3635 TSFVMV--DGEPVQKIEKDIDFQVTYREMGTNKLDDIINGFVKPFDLEKAPLLRVEIIHV 3692 Query: 128 TDREETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQ 187 TD +E V+++DMHHII+DG S+ I ++LA LY +EL L +QYKDY+V Q L E+ Sbjct: 3693 TD-DEHVIVLDMHHIISDGVSMGIFTQELAELYNGKELSPLSIQYKDYSVWQRELFTQEE 3751 Query: 188 WNRQEEYWLGVFHEPVPAL--PWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTE 245 +QEEYW+ VF E VP L P D + ++ E +F ID L ++A+ Sbjct: 3752 MKKQEEYWMHVFKEEVPVLNMPTDYKRPPIQSTE--GDLVHFEIDSDIYVNLKKMAKEHG 3809 Query: 246 STLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLS 305 TL+M+L+A +T LLSK + E+IVVG P +GR H+ L I+G+ VNTLA+R + R +S Sbjct: 3810 VTLYMLLLAGYTTLLSKYTGQEEIVVGSPIAGRPHDDLKQIMGIFVNTLAMRNYPKRDVS 3869 Query: 306 FQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QIDA 364 FQ+YL +VKD ++AYENQDYP D LVEKL+ ++ LF+ M + + +I Sbjct: 3870 FQDYLKEVKDNALKAYENQDYPFDELVEKLDLKRDMSRSALFDTMLVLQNFDYDDFEIQG 3929 Query: 365 IDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITS 424 + + + KFDL V+E S+ + Y LF +E + L I++ + I Sbjct: 3930 LTFSPYQMKAHVSKFDLTLTAVEEERSIKCVLNYRTKLFKKETVERLAKHLIQVFKEIIE 3989 Query: 425 NLETGLGDLL 434 E + D++ Sbjct: 3990 KPEQSIQDIM 3999 Score = 92.8 bits (229), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 90/320 (28%), Positives = 142/320 (44%), Gaps = 36/320 (11%) Query: 34 AYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIELDADSGM---LRQKINPAVSFA 90 AY +I IKG +D EE+ +++ RHE LR + D + LR + + F+ Sbjct: 17 AYFEQIILDIKGYVDETIFEESFNEIMKRHEVLRASFNYKLDEPLHVILRDR---KIKFS 73 Query: 91 F-PVYELSETETVL-----LIQDFVRPFRLDKPPLFRTALIRLTDREETVLIIDMHHIIT 144 + V L L ++ D V+ F L K L R LI+ D V I HHI+ Sbjct: 74 YNDVSNLDLNTKDLYVEKYIVDDKVKGFDLTKETLMRICLIKTNDNSYKV-IWSFHHILL 132 Query: 145 DGTSVSILLKDLAALY------ENRELEVLKLQYKDYA---VRQSLLAGTEQWNRQEEYW 195 DG + I+L +L +Y E +LE + Y DY Q G + W++ Y Sbjct: 133 DGWCIGIILDELFTIYSHKMKGEEHQLEDPR-PYSDYINWLNNQDNEEGLKYWSK---YL 188 Query: 196 LGVFHEPVPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTESTLFMVLMAA 255 G +E LP + AG+ R ++ + +LA TL V+ + Sbjct: 189 EG--YELTATLP---KFNNSSAGKYQRREKVIEFSKELTDKITQLANKNNVTLNTVMQSI 243 Query: 256 FTALLSKLSDCEDIVVGMPTSGRHH--EGLDNIVGMLVNTLAVRFFACRKLSFQEYLYQV 313 + +L+K ++ ED+V G SGR EG++N++G+ +NT+ R + SF+E L Sbjct: 244 WGLILAKYNNSEDVVFGTVVSGRDAAVEGIENMLGLFINTIPTRIKLQSEKSFKEVLKAT 303 Query: 314 KDKLIEAYENQDYPLDRLVE 333 + +A E DY L E Sbjct: 304 QH---DAIEGNDYNYINLAE 320 Score = 89.7 bits (221), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 83/331 (25%), Positives = 142/331 (42%), Gaps = 32/331 (9%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP + Q+ + + AY ++ +KG +D EE+L ++ RHE LRT Sbjct: 5081 EKIYPLANMQQGMLFHALEDPQSGAYFEQLVIDVKGFIDVNLFEESLNDIMKRHEILRTA 5140 Query: 70 IELDADSGMLRQKINPAVSFAFPVYEL--------SETETVLLIQDFVRPFRLDKPPLFR 121 IE + + + I F ++ E+ T + QD + F K L R Sbjct: 5141 IEYEI-TEQPKNVIIKGRKIGFRYRDIRQQGIDQQKESITTYIEQDREKGFDFSKDVLIR 5199 Query: 122 TALIRLTDREETVLIIDMHHIITDGTSVSILLKDLAALYENREL-EVLKLQ----YKDYA 176 LI+ D+ T+ I HHI+ DG I+L +L +Y N+++ + L+ Y DY Sbjct: 5200 LELIQTDDKAYTI-IWSNHHILFDGWGRGIILGELFHIYGNKQVGQYPNLEEPRPYSDYI 5258 Query: 177 V---RQSLLAGTEQWNRQEEYWLGVFHEP--VPALPWDGRGTEHRAGEDPSRTAYFAIDE 231 Q G + W + +L + +P VP+ D H + Sbjct: 5259 RWLGEQEKEEGIQYWKQ----YLAGYQKPAKVPSFKIDSTREYH------GQETLIEFSR 5308 Query: 232 QTACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHE--GLDNIVGM 289 + + LA TL VL + +L+K + +D+V G SGR + G++ +VG+ Sbjct: 5309 ELTKKMTELANQNNVTLNTVLQTLWGIILAKYNHTDDVVFGSVVSGRDAKVAGIEKMVGL 5368 Query: 290 LVNTLAVRFFACRKLSFQEYLYQVKDKLIEA 320 +N + R + SF+ L +V+ + IE+ Sbjct: 5369 FINAIPTRINIKEQKSFKNILKEVQQQAIES 5399 Score = 83.2 bits (204), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 86/338 (25%), Positives = 142/338 (42%), Gaps = 34/338 (10%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP + Q+ + + AY + I G +D L+ + K++ R+E LR + Sbjct: 2531 EKIYPLANMQKGMLFHALENKNSKAYFEQTVMDITGYVDVEILKTSFNKIMQRYEILRAS 2590 Query: 70 IELDADSGMLRQKINPAVSFAFPVYELSETETV---LLIQDFV-----RPFRLDKPPLFR 121 E + G RQ I ++SE T+ L I+++ + F L K L R Sbjct: 2591 FEYEI-VGEPRQIIIADREIGVQYCDISERGTIEKELFIKNYREEDTEKGFNLSKDTLMR 2649 Query: 122 TALIRLTDREETVLIIDMHHIITDGTSVSILLKDLAALY------ENRELEVLKLQYKDY 175 LIR TD L+ HHI+ DG + I+L +L +Y E ELE K Y DY Sbjct: 2650 VCLIR-TDENLYKLVWSHHHILLDGWCLGIVLGELFTVYGKLINGEEYELEETK-PYSDY 2707 Query: 176 AV---RQSLLAGTEQWNRQEEYWLGVFHEP--VPALPWDGRGTEHRAGEDPSRTAYFAID 230 Q G W E +L + E +P L +E+ R Sbjct: 2708 IKWLEEQDKEEGKSYW----EQYLDGYEEKAQIPKLQITKNNSEYL-----RREKVIEFS 2758 Query: 231 EQTACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHH--EGLDNIVG 288 + + +LA T V + + +L+K ++ +++V G SGR +G++ ++G Sbjct: 2759 NELTNKITQLANRNSVTFNTVFQSIWGIILAKYNNTDEVVFGTIVSGREAPVDGIEKMIG 2818 Query: 289 MLVNTLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDY 326 + +N + R + F+E L V+ + I A N +Y Sbjct: 2819 LFINAIPTRINLGKNQKFKEVLTVVQSEAI-ASNNYNY 2855 >C3H9Z8.1 C3H9Z8_BACTU Glutamate racemase Length = 5273 Score = 300 bits (769), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 166/431 (38%), Positives = 257/431 (59%), Gaps = 12/431 (2%) Query: 8 KQETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLR 67 +++ YYP S AQR +++ +K+ G G +YN+P +IKG LD +LE+A +KL+ RHESLR Sbjct: 2715 EEQDYYPLSSAQRRLYILNKIEGSGVSYNMPFAMKIKGDLDVHQLEQAFRKLIERHESLR 2774 Query: 68 TTIELDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRL 127 T+ + G QKI ++ E+ + +I FV+PF L+K PL R +I + Sbjct: 2775 TSFVMV--DGEPVQKIKKDINSQVTYREMGTNKLDDIINGFVKPFDLEKAPLLRVEIIHV 2832 Query: 128 TDREETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQ 187 TD +E V+++DMHHII+DG S+ I +++LA LY ++L L +QYKDY+ Q L E+ Sbjct: 2833 TD-DEHVMVLDMHHIISDGVSMGIFMQELAELYNGQKLSPLSIQYKDYSEWQRGLFTQEE 2891 Query: 188 WNRQEEYWLGVFHEPVPAL--PWDGRGTEHR--AGEDPSRTAYFAIDEQTACALHRLAQT 243 +QE+YW+ VF+E VP L P D + + R AG+ + I+ +T L++LA Sbjct: 2892 ITKQEKYWMNVFNEEVPVLNMPTDYKRPKRRSFAGDRIN----LKINSETYNQLNKLATE 2947 Query: 244 TESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRK 303 E T++M+++A +T LLSK S EDIVVG P +GR H L+N++GM VNTLA+R + Sbjct: 2948 NEVTMYMLMLAGYTTLLSKYSGQEDIVVGSPIAGRKHVDLNNVMGMFVNTLAMRNYPKGN 3007 Query: 304 LSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAA-EQI 362 SF+EYL +VK+ ++AYENQDY + LVEK+N ++ PLF+ M F + + Sbjct: 3008 RSFREYLKEVKENTLKAYENQDYQFEELVEKVNVRRDISRNPLFDTMLVFQHTDNMLLNL 3067 Query: 363 DAIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVI 422 D + + KFD+ V + LG+EI Y +L+ +E I + FI +++ + Sbjct: 3068 DGLKVSMLEDQREIVKFDITIHVSELEHGLGLEIEYCTALYKKETIERFLEHFINVLREV 3127 Query: 423 TSNLETGLGDL 433 N E L ++ Sbjct: 3128 VENPEQKLSEI 3138 Score = 228 bits (581), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 138/440 (31%), Positives = 239/440 (54%), Gaps = 23/440 (5%) Query: 9 QETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRT 68 ++ YY SP+Q+ ++M + AY++P+ ++G ++ RLE+A +K ++RHE LRT Sbjct: 1674 KKDYYATSPSQKRMYMLSMMENNRGAYHIPMALLVEGEIECNRLEKAFRKFIDRHEILRT 1733 Query: 69 TIE-LDADSGMLRQKINPAVSF--AFPVYELSETE-------TVLLIQDFVRPFRLDKPP 118 E LD + L Q++ V F + ++ T+ T + ++ +PF L+KP Sbjct: 1734 GFEVLDNE---LVQRVYDKVDFDLEYQCLDIVVTDDEGLRDLTSKMCKESTKPFDLNKPS 1790 Query: 119 LFRTALIRLTDREETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVR 178 L R LI++ E+ +L+++ HHII DG S I + ++ LY N +L + +QYKDY Sbjct: 1791 LMRAKLIKIG-VEKHILVVNFHHIIADGVSQGIFMNEILDLYNNLDLPKINIQYKDYVEW 1849 Query: 179 QSLLAGTEQWNRQEEYWLGVF-HEPVP-ALPWDGR--GTEHRAGEDPSRTAYFAIDEQTA 234 + + +QE+YWL ++ H P LP+D R + AGE+ AYF I+++ + Sbjct: 1850 NNTYNQSNAIKKQEQYWLNLYSHLPSKLELPYDYRKENIDTFAGEN----AYFHIEKELS 1905 Query: 235 CALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTL 294 + R+A+ T STL+M++++A+ LL K + DIVVG SGR H+ L NI G+ VNT+ Sbjct: 1906 EQIRRVAKDTGSTLYMLMLSAYHILLHKYTGKTDIVVGTAASGRLHQDLQNIFGVFVNTI 1965 Query: 295 AVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFA 354 A+R SF+E L QVK+ I A+EN +Y D L+ ++ + PLF+ MF Sbjct: 1966 ALRNNIDATKSFKEILEQVKENTITAFENSEYQFDELIRSIDYERDSNRNPLFDTMFVLE 2025 Query: 355 EMEA-AEQIDAIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELIS 413 + + ++ A+++ + KFD+ F ++ + + + Y LF + I + Sbjct: 2026 DAKLFTKKQGALNLSPIIFELDNAKFDITFNILDYDDEIVLNVEYSTGLFKRDTILRMTE 2085 Query: 414 GFIEIIQVITSNLETGLGDL 433 +I I++ I+ NL + + Sbjct: 2086 NYINILREISGNLSISVNKI 2105 Score = 87.8 bits (216), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 102/449 (22%), Positives = 193/449 (42%), Gaps = 43/449 (9%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP + Q+ + + Y ++ IKG +D LE++ ++ RHE LR Sbjct: 4222 EKIYPLANMQKGMLFHALEDKNSSMYFEQIVMDIKGTVDVDILEKSFNTIMRRHEILRAA 4281 Query: 70 IELDADSGMLRQKINPAVSFAFPVYELSET---ETVLLIQDFV-----RPFRLDKPPLFR 121 E + R I F Y++ + + I++++ + F L + L R Sbjct: 4282 FEYELVEEP-RHVILQDRKVGFKYYDIQDESIEQKTKFIENYLQNDKQKGFNLSEDTLMR 4340 Query: 122 TALIRLTDREETVLIIDMHHIITDGTSVSILLKDLAALYENRELE------VLKLQYKDY 175 +LI++ +++ L+ HHI+ DG + I+L + +Y R+++ Y DY Sbjct: 4341 ISLIQM-NQDSYKLVWSHHHILLDGWCLGIILGEFFDVY-GRKMKGEDSHLAEPTPYSDY 4398 Query: 176 AV---RQSLLAGTEQWNRQEEYWLGVFHEP--VPALPWDGRGTEHRAGEDPSRTAYFAID 230 Q G W +L + E VP + ++ E + Sbjct: 4399 IRWLEEQDKEEGLAHWKS----YLDGYEEQAQVPKIL-------NKVNEYKRKEKMIEFS 4447 Query: 231 EQTACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHH--EGLDNIVG 288 ++ + +LA + T VL A + LL++ ++ ED+V G SGR EG++ +VG Sbjct: 4448 KEMNRNIIQLANRNQVTFNTVLQAIWGILLARYNNIEDVVFGTVVSGREAKVEGIEAMVG 4507 Query: 289 MLVNTLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFN 348 + +NT+ R + SF+E L V+D E+ EN Y L E + H+L+ + + Sbjct: 4508 LFINTIPTRVKLEKDSSFKEVLRNVQD---ESIENNKYNYINLAE-IQSLHDLKRNLIDH 4563 Query: 349 VM-FQFAEMEAAEQIDAIDMVSFGHDSVPGKFDLHF---IVVQESSSLGIEITYFESLFS 404 VM FQ ++ + A F ++ G+ ++ IV L +++TY E ++ Sbjct: 4564 VMVFQNYSLDDSSFNHAESNTGFMCQNIRGEEQTNYGFNIVAIPGEQLVLKLTYNEKIYP 4623 Query: 405 EEAIGELISGFIEIIQVITSNLETGLGDL 433 +E I + ++ + + N + L ++ Sbjct: 4624 QEIIDNIEMHLKKVTEQVVLNEDKKLNEI 4652 Score = 73.6 bits (179), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 96/423 (22%), Positives = 183/423 (43%), Gaps = 36/423 (8%) Query: 32 GTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIELDADSGMLRQKINPAVSFAF 91 G A N+ V I +D R AL+KL+NRH LRT + + +L ++ +V Sbjct: 663 GAATNLTVEFEIDINID--RFNSALQKLINRHPILRTIVFENGTQRILEGELLYSVD-TV 719 Query: 92 PVYELSETETVL--------LIQDFVRPFRLDKPPLFRTALIRLTDREETVLIIDMHHII 143 V L++ + ++ +I + P PLF L + ++ +++ +I Sbjct: 720 DVRHLNQEDIMIRILEQRQKMIAKIIDPSTW---PLFEIKAFILPNNQK-YFCLNIDPLI 775 Query: 144 TDGTSVSILLKDLAALYENRELEVLKLQY--KDYAVRQSLLAGTEQWNRQEEYWLGVFHE 201 D +S+ IL+K+ Y L++ +L+Y +DY + + + ++ + E+YWL Sbjct: 776 CDDSSMKILIKEFKMFYNQPSLQLPELEYNFRDYVLATNEFRQSNRYKKDEKYWLNKLDN 835 Query: 202 --PVPALPWDGRGTEHRAGEDPS--RTAYFAIDEQTACALHRLAQTTESTLFMVLMAAFT 257 PALP E E P+ + + F ++ +T L + A+ T VL AA+ Sbjct: 836 FPSAPALPLKCNPLEI---EKPTFNKCSEF-LERETWNRLKQKAREKNLTPTSVLCAAYA 891 Query: 258 ALLSKLSDCEDIVVGMPTSGR--HHEGLDNIVGMLVNTLAVRFFACRKL-SFQEYLYQVK 314 +L+ S+ V + R H+ + I+G + + A + SF ++ +V+ Sbjct: 892 YVLAYWSNQSRFAVNLTVFNRIPFHQDVKKIIGDFTTLMLLDINAKDSIESFWKFAAKVQ 951 Query: 315 DKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAEQ-----IDAIDMVS 369 D L+EA E++ Y + + H + + + ++F E ++ ID + Sbjct: 952 DTLLEALEHRHYDGVDFIRAIGKKHRMVNQAIMPIVFTSVLSEDSDDSFNHLIDFEKIKF 1011 Query: 370 FGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEII-QVITSNLET 428 F + D V + + L I Y E LF I + +I ++ QVI ++ + Sbjct: 1012 FSTRTSQVYIDNQ--VYELNGGLYITWDYVEQLFEINVIKSMFEQYINVLNQVIFNDQVS 1069 Query: 429 GLG 431 G+ Sbjct: 1070 GIN 1072 >Q9R9J0.1 MYCB_BACSU Mycosubtilin synthetase subunit B ATP-dependent tyrosine adenylase ATP-dependent asparagine adenylase 2 ATP-dependent glutamine adenylase ATP-dependent proline adenylase EC=2.3.1.- Length = 5369 Score = 298 bits (762), Expect = 9e-79, Method: Compositional matrix adjust. Identities = 164/423 (38%), Positives = 247/423 (58%), Gaps = 4/423 (0%) Query: 12 YYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIE 71 YYP S AQ+ +++ + L G +YN+ + +KG LD +L++A KL++RHESLRT + Sbjct: 3891 YYPVSSAQKRLYILNHLEGGELSYNMLGLMTVKGELDRDKLQQAFDKLIHRHESLRTGFK 3950 Query: 72 LDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRLTDRE 131 + G Q + V FA Y E E I FVR F+L++PPL R LI L Sbjct: 3951 MV--DGEPVQYVLDHVEFAVESYYAKEDEIDHCISQFVRAFQLEEPPLLRVGLIELQPNH 4008 Query: 132 ETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQWNRQ 191 +L+ DMHHII+DGTS+++L+K+ Y+ EL L++QYKDY+V Q+ A EQ +Q Sbjct: 4009 -AILMFDMHHIISDGTSMNVLIKEFVRAYQGAELPPLRIQYKDYSVWQTGEARLEQIQKQ 4067 Query: 192 EEYWLGVFHEPVPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTESTLFMV 251 E+YWL ++ +P L + T +F IDE+ + L +LA TESTL+MV Sbjct: 4068 EDYWLELYSGDIPVLHLPTDYIRPSTRDFTGATLHFTIDEKKSEGLKQLALKTESTLYMV 4127 Query: 252 LMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLSFQEYLY 311 L+A++T LLSK S EDIVVG P +GR H LD+I+GM VNTLA+R + ++ +F +YL Sbjct: 4128 LLASYTLLLSKYSGQEDIVVGSPIAGRPHADLDSIIGMFVNTLAMRNYPAKEKTFSQYLA 4187 Query: 312 QVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QIDAIDMVSF 370 +VK+ ++AYE+QDYP + LV++LN + +L PLF+ MF E + +D + + Sbjct: 4188 EVKENALKAYEHQDYPFEALVDQLNIARDLSRNPLFDTMFVLQNTEQEQLGMDGLTFKPY 4247 Query: 371 GHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITSNLETGL 430 KFDL V+E + + + Y +LF E + ++ F+++I I + E L Sbjct: 4248 PSKHTMAKFDLTLTAVEEETHIHCTMEYLTTLFKPETVERMMRHFVQLIDAIIEHPEARL 4307 Query: 431 GDL 433 L Sbjct: 4308 ASL 4310 Score = 281 bits (718), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 151/416 (36%), Positives = 236/416 (56%), Gaps = 8/416 (1%) Query: 13 YPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIEL 72 YP S Q+ ++++ ++ G +YN+P I ++G +D RL+ A +L+ RHESLRT E+ Sbjct: 4931 YPVSSVQKMVYLSTQIEGGELSYNMPGILTLEGRIDMDRLQTAFHRLIQRHESLRTGFEM 4990 Query: 73 DADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRLTDREE 132 M Q + P V F Y+ + E L + FVRPF L + PL R LI L ++E+ Sbjct: 4991 IRGEPM--QMVKPEVEFTIERYKATAEEVEELFRTFVRPFDLSQAPLLRVGLIEL-EQEK 5047 Query: 133 TVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQWNRQE 192 + + DMHHI+TDG S++I +++L LY+ +EL L++QYKD+ Q E+ +QE Sbjct: 5048 HIFMFDMHHIVTDGASMNIFIEELIQLYDGKELAPLRIQYKDFTAWQQQAEQKERIKKQE 5107 Query: 193 EYWLGVFHEPVPA--LPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTESTLFM 250 +YWL VFHE +P+ LP D + R+ E + F ++E + +L + T ST +M Sbjct: 5108 DYWLDVFHEALPSFELPKDFARPQVRSFE--GKRYNFVLNESVVQGVKQLEELTGSTTYM 5165 Query: 251 VLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLSFQEYL 310 +L AA+T LL+K S EDIVVG P +GR H+ L +I+GM VNTLA+R + +F++Y+ Sbjct: 5166 ILFAAYTILLAKYSGQEDIVVGTPVAGRVHDDLQHIIGMFVNTLAIRTAPAGEKTFKDYV 5225 Query: 311 YQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QIDAIDMVS 369 + K+ +++AYENQ+YP + LVEKL +L PLF+ MF E + +ID++ + Sbjct: 5226 TETKETMLKAYENQEYPFEELVEKLGVQRDLSRNPLFDTMFVLQNTEQTDIEIDSLAVRP 5285 Query: 370 FGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITSN 425 + KFDL + Y LF + I L ++ I+ + N Sbjct: 5286 YEETHAVAKFDLQLTFEMHQHEIQGSFDYCTKLFKKRTIATLAQDYVMILSAVIQN 5341 Score = 85.1 bits (209), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 97/426 (22%), Positives = 172/426 (40%), Gaps = 29/426 (6%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP +P Q+ + L +Y ++G L R E +L L ++ LRT Sbjct: 2827 ENVYPLTPMQKGMLFHSLLDEDSNSYFEQASFDLQGELKIDRFEASLDHLFAKYAVLRTR 2886 Query: 70 IELDADSGMLR-----QKINPAVSFAFPVYELSETETVLLIQ--DFVRPFRLDKPPLFRT 122 + L+ Q++ + + E + + Q D + F L + PL R Sbjct: 2887 FYSGWNDIPLQIVYKTQRMKVHFTDLRDIDENQRKDEIASYQSEDKAKGFDLARDPLMRI 2946 Query: 123 ALIRLTDREETVLIIDMHHIITDGTSVSILLKD----LAALYENRELEVLKLQYKDYAVR 178 A+ R+ +R+ LI HHI+ DG + ++ K+ L E RE + L Y D + Sbjct: 2947 AIFRIEERKYH-LIWSFHHIVMDGWCLPLITKEAFEHYIGLQEGRETD---LAYTDPYSK 3002 Query: 179 QSLLAGTEQWNRQEEYWLGVFHEPVPALPWDGRGTEHRAGEDPSRTAY----FAIDEQTA 234 + N + YW E + + R R + AY +++ Sbjct: 3003 YIEWLDQQDQNAAKRYW----REYLEGYKGETRILHKRPQHERKAYAYANEICRFNQKQT 3058 Query: 235 CALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHE--GLDNIVGMLVN 292 L R+A TL ++ + LL K S D+V G SGR E G++ ++G+ +N Sbjct: 3059 RQLQRIANQHHVTLNTLIQTLWGILLQKYSGTGDVVFGSVVSGRPAEISGVEQMIGLFIN 3118 Query: 293 TLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQ 352 T+ VR SF E + V+D + + YPL + + NL L + Sbjct: 3119 TIPVRICCDEGSSFVETMKMVQDNALASQSYDTYPLYEIQAQTEQKQNLIDHILIFENYP 3178 Query: 353 FA-EMEAAEQIDAIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGEL 411 ++E +++++F H +D + +V+ L + Y ++++ + + E Sbjct: 3179 IGQQVEEGHNAAELNIMNF-HMEEHSHYDFNMVVI-PGEQLNVHFGYNQNVYEQSEV-ER 3235 Query: 412 ISGFIE 417 ISG E Sbjct: 3236 ISGHFE 3241 Score = 76.6 bits (187), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 80/340 (23%), Positives = 138/340 (40%), Gaps = 34/340 (10%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP +P Q+ + AY + + G LD ++L L R+E RT Sbjct: 1316 ENIYPLTPMQKGMLFHSLFDSHSGAYFQQTMFELHGDLDIDSFSKSLDDLSKRYEIFRTN 1375 Query: 70 IELDADSGMLRQKINPAVSFAFPVYELSETE--------TVLLIQDFVRPFRLDKPPLFR 121 D + Q I F +L E + +D +R F L K L R Sbjct: 1376 FLKGKDQPL--QIIFKTKKIGFQFIDLREMDQARQDDRICAYAKEDKLRGFDLAKDVLMR 1433 Query: 122 TALIRLTDREETVLIIDMHHIITDGTSVSILLKDL----AALYENRELEVLKL----QYK 173 ++R TD I HHI+ DG + ++ K++ AL + ++ E + QY Sbjct: 1434 VIVLR-TDDTTYRFIWSFHHILMDGWCLPLITKEIFDHYFALLQQKQPEQAAITPYSQYI 1492 Query: 174 DYAVRQSLLAGTEQWNRQEEYWLGVFHEPVPALPWDGRGTEHRAGED---PSRTAYFAID 230 ++ RQ W++ +L + E L H+A ++ P + + AID Sbjct: 1493 EWLDRQDAEEAKRYWDQ----YLEGYEEQTVLL-----KDSHQAEDEHYFPEKVS-CAID 1542 Query: 231 EQTACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHE--GLDNIVG 288 + + A TL +L A+ LL K + D+V G SGR ++ ++G Sbjct: 1543 TDLTLKMKQTASKHHVTLNTLLQTAWGILLQKYNRSRDVVFGSVVSGRPSAIPNVETMIG 1602 Query: 289 MLVNTLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPL 328 + +NT+ VR +F E + + +++ + + + YPL Sbjct: 1603 LFINTIPVRIQCEAGTTFAELMKRTQERAVASQTYETYPL 1642 Score = 63.2 bits (152), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 50/242 (20%), Positives = 113/242 (46%), Gaps = 26/242 (10%) Query: 188 WNRQEEYWLGVFHEP-----VPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQ 242 + Q YW +F E +P + R G ++ Y ++ + + + +A Sbjct: 4 FKNQVTYWANLFDEEDSLSVIPYFKTAENASLTRVGYQ-EKSIYRSLSPEVSQRILTMAN 62 Query: 243 TTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLD--NIVGMLVNTLAVRFFA 300 +E +++L+A LL K +D ++G+PT + N + +L NTL+ Sbjct: 63 HSEMATYLILLAGIECLLYKYTDRASTILGIPTVSKQKSSSSTVNTIVLLKNTLS----- 117 Query: 301 CRKLSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE 360 C+ +F+ Q+K + ++ +NQ+ P ++V+ +N ++ + PL + + E+ + + Sbjct: 118 CQS-TFKTVFEQLKKAVNDSLKNQNLPFRKIVQHVNVQYDNENIPLIHTVVSLNEIHSLQ 176 Query: 361 QIDAIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQ 420 + I + H FDL E+S + +++ Y +L+ E+ + +++S +++ Sbjct: 177 FKEDIATDTLFH------FDL------ENSEIHLKLIYNGNLYDEDYMDQMVSHLNQLLS 224 Query: 421 VI 422 VI Sbjct: 225 VI 226 >Q93I55.1 Q93I55_BACSU Iturin A synthetase B Length = 5362 Score = 295 bits (755), Expect = 6e-78, Method: Compositional matrix adjust. Identities = 162/423 (38%), Positives = 252/423 (59%), Gaps = 4/423 (0%) Query: 12 YYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIE 71 YYP S AQ+ +++ + L G +YN+ + ++G LD +L++A + L+ RHESLRT + Sbjct: 3886 YYPVSSAQKRLYILNHLEGGELSYNMLGLMTVEGKLDRDKLQQAFRTLILRHESLRTGFK 3945 Query: 72 LDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRLTDRE 131 + AD ++ ++ A +F Y+ E + L I+ F+RPF LD+PPL R LI L + Sbjct: 3946 M-ADGEPVQYVLDHA-AFEAEWYQGEEDDADLYIRQFIRPFHLDEPPLLRVGLIELQP-D 4002 Query: 132 ETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQWNRQ 191 +L+ DMHHII+DGTS+S+L+K+ +YE L L++QYKDYAV Q+ A +Q +Q Sbjct: 4003 RGILMFDMHHIISDGTSMSVLIKEFIRIYEGETLPPLRIQYKDYAVWQTSEARLQQIQKQ 4062 Query: 192 EEYWLGVFHEPVPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTESTLFMV 251 E YWL ++ VP L A + T +F +D+Q + L +LA TESTL+MV Sbjct: 4063 EAYWLELYSGDVPVLHLPADYIRPSARDFAGATMHFTLDKQKSDGLKQLASQTESTLYMV 4122 Query: 252 LMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLSFQEYLY 311 L+A++T LLSK S EDI+VG P +GR H L+ I+GM VNTLA+R + + +F +YL Sbjct: 4123 LLASYTLLLSKYSGQEDIIVGSPIAGRPHADLEPIIGMFVNTLAMRNYPEKGKTFSQYLS 4182 Query: 312 QVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QIDAIDMVSF 370 +VK+ ++AYE+QDYP + L+++LN + +L PLF+ MF E + +I+ + + Sbjct: 4183 EVKENALKAYEHQDYPFEALIDQLNIARDLSRNPLFDTMFVLQNTEQEQLEINDVTFKPY 4242 Query: 371 GHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITSNLETGL 430 + KFDL V+E +S+ + Y +LF E I ++ F +++ I E L Sbjct: 4243 PNGHTMAKFDLTLTAVEEGASIQFTLEYLTALFKPETIERMMGHFEQLVDSIIKQPEAEL 4302 Query: 431 GDL 433 L Sbjct: 4303 ARL 4305 Score = 264 bits (675), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 148/429 (34%), Positives = 240/429 (55%), Gaps = 8/429 (1%) Query: 8 KQETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLR 67 K + YP S Q+ ++++ ++ G +YN+P I ++G LD RL+ A ++L+ RHESLR Sbjct: 4919 KAKDVYPVSSVQKMVYLSTQIEGGELSYNMPGILTLEGKLDMNRLQTAFQRLIQRHESLR 4978 Query: 68 TTIELDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRL 127 T E+ G Q I V F+ Y+ + E + FVRPF L + PL R LI L Sbjct: 4979 TGFEMV--RGEPVQVIKSQVEFSMERYKATADEVEECFRTFVRPFDLSQAPLLRAGLIEL 5036 Query: 128 TDREETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQ 187 +++ + + DMHHIITDG S++I +++L LY+ +EL L++QYKD+ + E+ Sbjct: 5037 -EQDLHIFMFDMHHIITDGASMNIFVEELIQLYDGKELAPLRIQYKDFTEWKHQKEQRER 5095 Query: 188 WNRQEEYWLGVFHEPVPA--LPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTE 245 QEEYWLGVFHE +P+ LP D R+ + + F +D+ + +L + T Sbjct: 5096 IKSQEEYWLGVFHEELPSFELPKDFARPPVRSFD--GKRHNFTLDKTVTQGIKQLEELTG 5153 Query: 246 STLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLS 305 +T +M+L +A++ LL+K S +DIVVG P +GR H L+ I+GM VNTLA+R + + Sbjct: 5154 TTAYMILFSAYSILLAKYSGQDDIVVGTPIAGRPHADLEPIIGMFVNTLAIRTAPMAEKT 5213 Query: 306 FQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QIDA 364 F +Y+ + K+ +++A+E+Q+YP + LVEKL +L PLF+ MF E + ++D+ Sbjct: 5214 FLDYITETKETMLKAFEHQEYPFEELVEKLGVKRDLSRNPLFDTMFVLQNTEQTDIEVDS 5273 Query: 365 IDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITS 424 + + + KFDL + + + Y LF ++ I L ++ I+ I Sbjct: 5274 LAVRPYEQTETAAKFDLQLNFLIDQDEIQGSFDYCTKLFKKKTIAVLAKDYVMILSAIMR 5333 Query: 425 NLETGLGDL 433 N L D+ Sbjct: 5334 NPSIPLKDI 5342 Score = 85.5 bits (210), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 97/445 (21%), Positives = 180/445 (40%), Gaps = 33/445 (7%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP +P Q+ + L ++Y ++G L + +L++L + LRT Sbjct: 2825 ENVYPLTPMQKGMLFHSLLDEASSSYFEQASFDLQGELKIDWFKASLERLFETYAVLRTR 2884 Query: 70 IEL---DADSGMLRQKINPAVSFA--FPVYELSETETVLLIQ--DFVRPFRLDKPPLFRT 122 D ++ + P + FA + E + + Q D + F L + PL R Sbjct: 2885 FYSGWNDTPLQIVYKTQTPQIHFADLRDIEEHLREDAIAAYQREDKAKGFDLARDPLMRI 2944 Query: 123 ALIRLTDREETVLIIDMHHIITDGTSVSILLKDL----AALYENRELEVLK-LQYKDYAV 177 A+ R+ DR+ LI HHI+ DG +S++ K++ +AL E RE E L + Y DY Sbjct: 2945 AIFRMEDRKYH-LIWSFHHIVMDGWCLSLITKEVFDHYSALQEGREPEPLSAVPYSDY-- 3001 Query: 178 RQSLLAGTEQWNRQEE-----YWLGVFHEPVPALPWDGRGTEHRAGEDPSRTAYFAIDEQ 232 E +RQ++ YW G + +H E D + Sbjct: 3002 -------IEWLDRQDQGAAKRYWGGYLEGYKGETTLLHKIAQHEQKEYAYANLICRFDHE 3054 Query: 233 TACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHE--GLDNIVGML 290 L ++A + TL ++ + LL K S D+V G SGR E ++ ++G+ Sbjct: 3055 QTKQLQQIANQHQVTLNTLIQTLWGVLLQKYSGSADVVFGSVVSGRPAEIPDVEQMIGLF 3114 Query: 291 VNTLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVM 350 +NT+ VR +F + + V+ + + YPL + + NL + Sbjct: 3115 INTIPVRIRCDEDSTFADTMQMVQQNALASQSYDTYPLYEIQAQTEQKQNLIDHIMIFEN 3174 Query: 351 FQFAEM--EAAEQIDAIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAI 408 + + E +++ +F H +DL+ +V+ L + + ++ + + + Sbjct: 3175 YPIGQQAEETGHHGTELNITNF-HMQEHSHYDLNVVVI-PGKQLAVHFGFNKNEYEKSEV 3232 Query: 409 GELISGFIEIIQVITSNLETGLGDL 433 L F +++Q + + DL Sbjct: 3233 ERLRGHFEKLMQQVLRQPSVKIEDL 3257 Score = 80.5 bits (197), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 84/341 (24%), Positives = 145/341 (42%), Gaps = 35/341 (10%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP +P Q+ + AY + + G L+ ++L L +++ RT Sbjct: 1316 ENIYPLTPMQKGMLFHSLFDPNSGAYFQQTMFDLHGDLEIDSFSKSLDGLSQKYDIFRTN 1375 Query: 70 IELDADSGMLRQKIN-PAVSFAF-PVYELSETETVLLIQ-----DFVRPFRLDKPPLFRT 122 L+ + F F + E+ E++ +IQ D +R F L+K L R Sbjct: 1376 FYRGWKDQPLQIIFKTKKIGFQFNDLREMKESQKEAMIQQYAREDKMRGFDLEKGALMRL 1435 Query: 123 ALIRLTDREETVLIIDMHHIITDGTSVSILLKDLA----ALYENRELEVLKL----QYKD 174 ++R TD + I HHI+ DG + ++ K++ AL + ++ E + QY + Sbjct: 1436 FILR-TDEKTYRFIWSFHHILMDGWCLPLITKEIFENYFALLQQKQPEQSSITPYSQYIE 1494 Query: 175 YAVRQSLLAGTEQWNRQEEYWLGVFHEPVPALPWDGRGTEHRAGED----PSRTAYFAID 230 + RQ T W+ +Y G +E LP D H A ED P + I Sbjct: 1495 WLGRQDAKEATAYWD---QYLEG--YEEQTGLPKD-----HHAAEDGRYVPEKVT-CDIS 1543 Query: 231 EQTACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNI---V 287 + R A TL +L A+ LL K + D+V G SGR G+ N+ + Sbjct: 1544 SDLTSKMKRTAGKHHVTLNTLLQTAWAVLLQKYNRSRDVVFGSVVSGR-PAGIPNVETMI 1602 Query: 288 GMLVNTLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPL 328 G+ +NT+ VRF +F + + +++ + + + + +PL Sbjct: 1603 GLFINTIPVRFRCEAGTTFAGLMKEAQERAVASQQFETHPL 1643 Score = 64.3 bits (155), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 75/300 (25%), Positives = 125/300 (41%), Gaps = 21/300 (7%) Query: 35 YNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIELDADSGMLRQKINPAVS--FAFP 92 YN V+ +L + L+KL H++LR T ++G Q A S + Sbjct: 2382 YNQAVMLHAPEGFQETQLRQTLQKLAEHHDALRMTFRT-TENGCEAQNEEIAQSGLYRLE 2440 Query: 93 VYELSETE----TVLLIQDFVRP-FRLDKPPLFRTALIRLTDREETVLIIDMHHIITDGT 147 V L E T+ D ++ RL PL + L + + + L+I +HH+I DG Sbjct: 2441 VLNLKEDSDPGRTIEAKADEIQSSMRLSDGPLMKAGLFQCANGDH--LLIAIHHLIIDGI 2498 Query: 148 SVSILLKDLAALYENRE-LEVLKLQYKD-----YAVRQSLLAGTEQWNRQEEYWLGVFHE 201 S ILL+D+ + Y+ E + V++L K +A R S A +E +++EYW + Sbjct: 2499 SWRILLEDIVSGYKQAENVRVIQLPQKTDSFQLWAKRLSEYAQSETIKQEQEYWTKIEQT 2558 Query: 202 PVPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTESTLFMVLMAAFTALLS 261 V LP D T H +D E+T L + + + + +L+ + +S Sbjct: 2559 EVKPLPKDFHET-HTTAKDSETATVEWTKEETELLLKQANRAYHTEINDLLLTSLGLSIS 2617 Query: 262 KLSDCEDIVVGMPTSGRHH--EGLD--NIVGMLVNTLAVRFFACRKLSFQEYLYQVKDKL 317 S E I + + GR + +D VG + V A +Y+ K+ L Sbjct: 2618 HWSGLEQIPIHLEGHGREQIIQDIDISRTVGWFTSLYPVVLHAQPGKEISDYIKTTKEGL 2677 Score = 63.2 bits (152), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 55/245 (22%), Positives = 118/245 (48%), Gaps = 38/245 (15%) Query: 191 QEEYWLGVFHEP--VPALPWDGRGTEHRAGEDPS--RTAY------FAIDEQTACALHRL 240 QE YW +F E + A P+ +A + S RT Y ++ + + + + Sbjct: 7 QETYWENLFDEEDGLSAFPY------FKAADKASLARTGYQEKCICRSLSPEVSQRIMTM 60 Query: 241 AQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEG---LDNIVGMLVNTLAVR 297 A ++ +++L+A LL K +D +++G+PT + G ++NIV +L NTL+ Sbjct: 61 ANHSDMAAYLILLAGIECLLYKYTDRTSLILGIPTVSKQKAGQSAVNNIV-LLKNTLS-- 117 Query: 298 FFACRKLSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEME 357 + +F+ Q+K+ + ++ +NQ+ P ++V L+ +N + PL + + E+ Sbjct: 118 ----NESTFKTVFGQLKEAVNDSLKNQNLPFRKMVRHLSVQYNDEHMPLIHTVVSLNEIH 173 Query: 358 AAEQIDAIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIE 417 + + + + H FDL E++ + +++ Y +L+ E I +++S + Sbjct: 174 SKQCKEDTATDTLFH------FDL------ENNGIHLKLFYNGNLYDERYINQIVSHLDQ 221 Query: 418 IIQVI 422 ++ VI Sbjct: 222 LLSVI 226 >B3TLA2.1 B3TLA2_BACSU Iturin A synthetase B Length = 5362 Score = 293 bits (750), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 162/423 (38%), Positives = 249/423 (58%), Gaps = 4/423 (0%) Query: 12 YYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIE 71 YYP S AQ+ +++ + L G +YN+ + ++G LD +L++A + L+ RHESLRT + Sbjct: 3886 YYPVSSAQKRLYILNHLEGGELSYNMLGLMTVEGKLDRDKLQQAFRTLILRHESLRTGFK 3945 Query: 72 LDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRLTDRE 131 + AD G Q + +F Y+ E + L I+ F+RPF LD+PPL R LI L + Sbjct: 3946 M-AD-GEPVQYVLDHAAFEAEWYQGEEDDADLYIRQFIRPFHLDEPPLLRVGLIELQP-D 4002 Query: 132 ETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQWNRQ 191 +L+ DMHHII+DGTS+S+L+K+ +YE L L++QYKDYAV Q+ A +Q +Q Sbjct: 4003 RGILMFDMHHIISDGTSMSVLIKEFIRIYEGETLPPLRIQYKDYAVWQTGEARLQQIQKQ 4062 Query: 192 EEYWLGVFHEPVPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTESTLFMV 251 E YWL ++ VP L A + T +F +D+Q + L +LA TESTL+MV Sbjct: 4063 EAYWLELYSGDVPVLHLPADYIRPSARDFAGATMHFTLDKQKSDGLKQLASQTESTLYMV 4122 Query: 252 LMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLSFQEYLY 311 L+A++T LLSK S EDI+VG P +GR H L+ I+GM VNTLA+R + + +F +YL Sbjct: 4123 LLASYTLLLSKYSGQEDIIVGSPIAGRPHADLEPIIGMFVNTLAMRNYPEKGKTFSQYLS 4182 Query: 312 QVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QIDAIDMVSF 370 +VK+ ++AYE+QDYP + L+++LN + +L PLF+ MF E + +I+ + + Sbjct: 4183 EVKENALKAYEHQDYPFEVLIDQLNIARDLSRNPLFDTMFVLQNTEQEQLEINDVTFKPY 4242 Query: 371 GHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITSNLETGL 430 + KFDL V+E + + + Y +LF E I ++ F +++ I E L Sbjct: 4243 PNGHTMAKFDLTLTAVEEGAGIQFTLEYLTALFKPETIERMMGHFEQLVDSIIKQPEAEL 4302 Query: 431 GDL 433 L Sbjct: 4303 ARL 4305 Score = 252 bits (643), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 145/429 (33%), Positives = 233/429 (54%), Gaps = 8/429 (1%) Query: 8 KQETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLR 67 K + YP S Q+ +++ ++ G YN+ I +G L RL A ++L+ HE LR Sbjct: 4919 KAKDVYPVSSVQKMVYLTTQIIGGELPYNMTGILETEGKLPLNRLLTAFQRLMQGHEPLR 4978 Query: 68 TTIELDADSGMLRQKINPAVSFAFPVYELSETETVLLIQDFVRPFRLDKPPLFRTALIRL 127 T +E+ + + Q I V F+ YE + E + FVRPF L + PL R LI L Sbjct: 4979 TVVEMVREEAV--QVIKSQVEFSMERYEATADEVEECFRAFVRPFDLSQAPLLRAGLIEL 5036 Query: 128 TDREETVLIIDMHHIITDGTSVSILLKDLAALYENRELEVLKLQYKDYAVRQSLLAGTEQ 187 +++ + + DMHHIITDG S++I ++ L LY+ +EL L++QYKD+ + E+ Sbjct: 5037 -EQDLHIFMFDMHHIITDGASMNIFVEKLIQLYDGKELAPLRIQYKDFTEWKHQKEQRER 5095 Query: 188 WNRQEEYWLGVFHEPVPA--LPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTE 245 QEEYWLGVFHE +P+ LP D R+ + + F +D+ + +L + T Sbjct: 5096 IKSQEEYWLGVFHEELPSFELPKDFARPPVRSFD--GKRHNFTLDKTVTQGIKQLEELTG 5153 Query: 246 STLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNIVGMLVNTLAVRFFACRKLS 305 ST +M+L +A++ LL+K S +DIVVG P +GR H L+ I+GM VNTLA+R + + Sbjct: 5154 STAYMILFSAYSILLAKYSGQDDIVVGTPIAGRPHADLEPIIGMFVNTLAIRTAPMAEKT 5213 Query: 306 FQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEMEAAE-QIDA 364 F +Y+ + K+ +++A+E+Q+YP + LVEKL +L PLF+ MF E + ++D+ Sbjct: 5214 FLDYITETKETMLKAFEHQEYPFEELVEKLGVKRDLSRNPLFDTMFVLQNTEQTDIEVDS 5273 Query: 365 IDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIEIIQVITS 424 + + + KFDL + + + Y LF ++ I L ++ I+ I Sbjct: 5274 LAVRPYEQTETAAKFDLQLNFLIDQDEIQGSFDYCTKLFKKKTIAVLAKDYVMILSAIMR 5333 Query: 425 NLETGLGDL 433 N L D+ Sbjct: 5334 NPSIPLKDI 5342 Score = 87.4 bits (215), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 98/445 (22%), Positives = 180/445 (40%), Gaps = 33/445 (7%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP +P Q+ + L ++Y ++G L + +L++L + LRT Sbjct: 2825 ENVYPLTPMQKGMLFHSLLDEASSSYFEQASFDLQGELKIDWFKASLERLFETYAVLRTR 2884 Query: 70 IEL---DADSGMLRQKINPAVSFA--FPVYELSETETVLLIQ--DFVRPFRLDKPPLFRT 122 D ++ + P + FA + E + + Q D + F L + PL R Sbjct: 2885 FYSGWNDTPLQIVYKTQTPQIHFADLRDIEEHLREDAIAAYQREDKAKGFDLARDPLMRI 2944 Query: 123 ALIRLTDREETVLIIDMHHIITDGTSVSILLKDL----AALYENRELEVLK-LQYKDYAV 177 A+ R+ DR+ LI HHI+ DG +S++ K++ +AL E RE E L + Y DY Sbjct: 2945 AIFRMEDRKYH-LIWSFHHIVMDGWCLSLITKEVFDHYSALQEGREPEPLSAVPYSDY-- 3001 Query: 178 RQSLLAGTEQWNRQEE-----YWLGVFHEPVPALPWDGRGTEHRAGEDPSRTAYFAIDEQ 232 E +RQ++ YW G + +H E D + Sbjct: 3002 -------IEWLDRQDQGAAKRYWSGYLEGYKGETTLLHKIAQHEQKEYAYANLICRFDHE 3054 Query: 233 TACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHE--GLDNIVGML 290 L ++A + TL ++ + LL K S D+V G SGR E ++ ++G+ Sbjct: 3055 QTKQLQQIANQHQVTLNTLIQTLWGVLLQKYSGSADVVFGSVVSGRPAEIPDVEQMIGLF 3114 Query: 291 VNTLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVM 350 +NT+ VR +F + + V+ + + YPL + + NL + Sbjct: 3115 INTIPVRIRCDEDSTFADTMQMVQQNALASQSYDTYPLYEIQAQTEQKQNLIDHIMIFEN 3174 Query: 351 FQFAEM--EAAEQIDAIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAI 408 + + E +++ +F H +DL+ +V+ L + + E+ + + + Sbjct: 3175 YPIGQQAEETGHHGTELNITNF-HMQEHSHYDLNVVVI-PGKQLAVHFGFNENEYEKSEV 3232 Query: 409 GELISGFIEIIQVITSNLETGLGDL 433 L F +++Q + + DL Sbjct: 3233 ERLRGHFEKLMQQVLRQPSVKIEDL 3257 Score = 80.9 bits (198), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 84/341 (24%), Positives = 145/341 (42%), Gaps = 35/341 (10%) Query: 10 ETYYPASPAQRSIFMADKLSGRGTAYNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTT 69 E YP +P Q+ + AY + + G L+ ++L L +++ RT Sbjct: 1316 ENIYPLTPMQKGMLFHSLFDPNSGAYFQQTMFDLHGDLEIDSFSKSLDGLSQKYDIFRTN 1375 Query: 70 IELDADSGMLRQKIN-PAVSFAF-PVYELSETETVLLIQ-----DFVRPFRLDKPPLFRT 122 L+ + F F + E+ E++ +IQ D +R F L+K L R Sbjct: 1376 FYRGWKDQPLQIIFKTKKIGFQFNDLREMKESQKEAMIQKYAREDKMRGFDLEKGALMRL 1435 Query: 123 ALIRLTDREETVLIIDMHHIITDGTSVSILLKDLA----ALYENRELEVLKL----QYKD 174 ++R TD + I HHI+ DG + ++ K++ AL + ++ E + QY + Sbjct: 1436 FILR-TDEKTYRFIWSFHHILMDGWCLPLITKEIFENYFALLQQKQPEQSSITPYSQYIE 1494 Query: 175 YAVRQSLLAGTEQWNRQEEYWLGVFHEPVPALPWDGRGTEHRAGED----PSRTAYFAID 230 + RQ W+ +Y G +E LP D H A ED P + I Sbjct: 1495 WLGRQDAKEAAAYWD---QYLEG--YEEQTGLPKD-----HHAAEDGRYVPEKVT-CDIS 1543 Query: 231 EQTACALHRLAQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEGLDNI---V 287 + R A TL +L A+ LL K + D+V G SGR G+ N+ + Sbjct: 1544 SDLTSKMKRTAGKHHVTLNTLLQTAWAVLLQKYNRSRDVVFGSVVSGRP-AGIPNVETMI 1602 Query: 288 GMLVNTLAVRFFACRKLSFQEYLYQVKDKLIEAYENQDYPL 328 G+ +NT+ VRF +F E + + +++ + + + + +PL Sbjct: 1603 GLFINTIPVRFRCEAGTTFAELMKEAQERAVASQKFETHPL 1643 Score = 64.3 bits (155), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 76/300 (25%), Positives = 124/300 (41%), Gaps = 21/300 (7%) Query: 35 YNVPVIRRIKGMLDAGRLEEALKKLVNRHESLRTTIELDADSGMLRQKINPAVS--FAFP 92 YN V+ +L + L+KL H++LR T ++G Q A S + Sbjct: 2382 YNQAVMLHAPEGFQETQLRQTLQKLAEHHDALRMTFRT-TENGCEAQNEEIAQSGLYRLE 2440 Query: 93 VYELSET----ETVLLIQDFVRP-FRLDKPPLFRTALIRLTDREETVLIIDMHHIITDGT 147 V L E T+ D ++ L PL + L + D + L+I +HH+I DG Sbjct: 2441 VMNLKEDPDPGRTIEAKADEIQSSMHLSDGPLMKAGLFQCADGDH--LLIAIHHLIIDGI 2498 Query: 148 SVSILLKDLAALYENREL-EVLKLQYKD-----YAVRQSLLAGTEQWNRQEEYWLGVFHE 201 S ILL+D+ + Y+ E V++L K +A R S A +E +++EYW + Sbjct: 2499 SWRILLEDIVSGYKQAENGRVIQLPQKTDSFQLWAKRLSEYAQSETIKQEQEYWTKIEQT 2558 Query: 202 PVPALPWDGRGTEHRAGEDPSRTAYFAIDEQTACALHRLAQTTESTLFMVLMAAFTALLS 261 V LP D T H +D A E+T L + + + + +L+ + +S Sbjct: 2559 EVKPLPKDFHET-HTTAKDSETAAVEWTKEETELLLKQANRAYHTEINDLLLTSLGLSIS 2617 Query: 262 KLSDCEDIVVGMPTSGRHH--EGLD--NIVGMLVNTLAVRFFACRKLSFQEYLYQVKDKL 317 S E I + + GR + +D VG + V A +Y+ K+ L Sbjct: 2618 HWSGLEQIPIHLEGHGREQIIQDIDISRTVGWFTSLYPVVLHAQPGKEISDYIKTTKEGL 2677 Score = 61.2 bits (147), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 54/245 (22%), Positives = 117/245 (47%), Gaps = 38/245 (15%) Query: 191 QEEYWLGVFHEP--VPALPWDGRGTEHRAGEDPS--RTAY------FAIDEQTACALHRL 240 QE YW +F E + A P+ +A + S RT Y ++ + + + + Sbjct: 7 QETYWENLFDEEDGLSAFPY------FKAADKASLVRTGYQEKCICRSLSPEVSQRIMTM 60 Query: 241 AQTTESTLFMVLMAAFTALLSKLSDCEDIVVGMPTSGRHHEG---LDNIVGMLVNTLAVR 297 A ++ +++L+A LL K +D +++G+PT + G ++NIV +L NTL+ Sbjct: 61 ANHSDMAAYLILLAGIECLLYKYTDRTSLILGIPTVSKQKAGQSAVNNIV-LLKNTLS-- 117 Query: 298 FFACRKLSFQEYLYQVKDKLIEAYENQDYPLDRLVEKLNGSHNLQGRPLFNVMFQFAEME 357 + +F+ Q+K+ + ++ +NQ+ P ++ L+ +N + PL + + E+ Sbjct: 118 ----NESTFKTVFGQLKEAVNDSLKNQNLPFRKMARHLSVQYNDEHMPLIHTVVSLNEIH 173 Query: 358 AAEQIDAIDMVSFGHDSVPGKFDLHFIVVQESSSLGIEITYFESLFSEEAIGELISGFIE 417 + + + + H FDL E++ + +++ Y +L+ E I +++S + Sbjct: 174 SLQCKEDTATDTLFH------FDL------ENNGIHLKLFYNGNLYDERYINQIVSHLDQ 221 Query: 418 IIQVI 422 ++ VI Sbjct: 222 LLSVI 226 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.136 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,464,241,057 Number of extensions: 99776593 Number of successful extensions: 250194 Number of sequences better than 1.0e-05: 2626 Number of HSP's gapped: 238692 Number of HSP's successfully gapped: 4929 Length of query: 443 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 304 Effective length of database: 1,751,175,118 Effective search space: 532357235872 Effective search space used: 532357235872 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)