BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0587.0002.p (612 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DFV6.1 B1DFV6_9BACL Histidine kinase internal region 369 e-100 C4G3Y1.1 C4G3Y1_ABIDE Putative uncharacterized protein 282 8e-74 B8I996.1 B8I996_CLOCE Putative sensor with HAMP domain 276 3e-72 B1DAS7.1 B1DAS7_9BACL Integral membrane sensor signal transducti... 267 3e-69 A7VQH7.1 A7VQH7_9CLOT Putative uncharacterized protein 245 8e-63 >B1DFV6.1 B1DFV6_9BACL Histidine kinase internal region Length = 599 Score = 369 bits (948), Expect = e-100, Method: Compositional matrix adjust. Identities = 209/556 (37%), Positives = 323/556 (58%), Gaps = 7/556 (1%) Query: 43 FSRSLIERTTRNVADESQLILSRTDYILRSAETAANIMVTNINRLYESYPAVQAVPLEQF 102 FS S +++T N+ E+ +I +R D I + ET ++I+V +INR+Y+ + + Sbjct: 40 FSDSTLQKTKVNIKGETSVISARMDNIYSNGETCSSILVKDINRIYQDLGIGEQNTYQNV 99 Query: 103 RFANLMQSRLSIDLSIFREVDAAVFVGKDGTVYTSYTSGGEEEAKGIAASGMLNTVREAG 162 RF N + + +L F+++++ ++ +Y S K + S ML +++ G Sbjct: 100 RFQNQILNEFDFNLRAFKDIESIAYMDSMNNLYVSDYRLNANMDKAMR-SRMLESLKAPG 158 Query: 163 SYGYSHWFGMEKRSYLTSNPDSPVLTLGKMVINIDTGEPLGTLFLIVREEQLSAFLQSSD 222 S WF M+ R YLT++P+SPVLT+GK V++I++GE LG + L +RE S+ Sbjct: 159 -IPTSVWFPMQTRDYLTTDPNSPVLTIGKRVVDIESGETLGIIILNIRESTFSSIFPMEG 217 Query: 223 PAASKAYYFVDEHRRVVAAADKSSLLQPLEPSMAARIGDRERADRAASFSYKDDGNLVTV 282 + VD + RVV++ DK +LLQP+ P+ + D + + + +G+ + V Sbjct: 218 IKGEDGFNIVDANGRVVSSTDKDALLQPV-PNANLLNWLQTGNDGESKYVHLGNGDYLIV 276 Query: 283 SR-FGRMDWELINVVSLKLLTADVQQNVRLTALVGALCLIFSLFGASFLSRMVASPLERL 341 + + W L + +K LT D N +VG LC I ++ + LSR +A P+ +L Sbjct: 277 KKEIPELGWTLYKQMMVKELTIDTYTNSFTIFVVGLLCTIIAIISSIVLSRHIAKPIIKL 336 Query: 342 TRAMRQVVSGDLRPVAAARTEDEIGTIAEAFNFMVGRVRELLKKVTEEQKRKREYELALI 401 TR + V G+L + +++DE+G +A FN M+ + LL KVT+EQ++KREYE ALI Sbjct: 337 TRVAKLVREGNLNTASEVKSQDEVGILAGTFNEMIVTINGLLNKVTQEQRKKREYEFALI 396 Query: 402 SAQIKPHFLYNTLDTIYVLNELDRNEEARDTTKALADFYRMVLNKGRELIILEKEARITD 461 AQIKPHF YNTLD IYVL E + A DTT ALADFYR+ L+KG+E+I + +E ++ + Sbjct: 397 QAQIKPHFFYNTLDLIYVLCEKGKTSLAADTTMALADFYRISLSKGKEIITIAEELKVAE 456 Query: 462 DYLAIMQIRYPDVFRYEIDI-PAELSGTPIPKLSLQPLVENAIYHGLKKKGSKGFIRIQA 520 DYL I + RY D+ + ID+ PA L T I KL++QPL+ENAIYHGL+ K + G I I+ Sbjct: 457 DYLFIQKTRYSDIIDFTIDVDPAILEYTII-KLTIQPLIENAIYHGLRPKMTPGKITIKG 515 Query: 521 CSTGGKVLVQVTDNGIGMDEERIEA-IMSGYSPEEETRSIGTYSVQQRLNLYFGEPYGLT 579 +++QV D+GIG E +A I P +S G SV +R+ LYFGE YG+ Sbjct: 516 FWDRQGIILQVIDDGIGFPTEEWQANIDPAAQPIPAGKSFGLKSVHERIQLYFGERYGIQ 575 Query: 580 VRSVVDEGTVVELSLP 595 V S + GT V +++P Sbjct: 576 VESGMSRGTKVTITIP 591 >C4G3Y1.1 C4G3Y1_ABIDE Putative uncharacterized protein Length = 576 Score = 282 bits (721), Expect = 8e-74, Method: Compositional matrix adjust. Identities = 180/586 (30%), Positives = 291/586 (49%), Gaps = 35/586 (5%) Query: 7 IRRWFGRLRFKSKVIAXXXXXXXXXXXXXXXXXXXXFSRSLIERTTRNVADESQLILSRT 66 ++ +F L + K++ ++ + N+ ++S+LI ++ Sbjct: 4 VKDFFKNLTIRQKIVTAYISLLLFPIGVILFLANSIYTEVAVSGAQNNITEKSRLIGNQI 63 Query: 67 DYILRSAETAANIMVTNINRLYESYPAVQAVPLEQFRFANLMQSRLSIDLSIFREVDAAV 126 ++ +AE+ + ++ +IN + + + + + Q +F + + + L I +F +D V Sbjct: 64 ISVIENAESCSEMLNLSINNIL-ALIRYEKIGIRQLKFYHGINNHLDIARQMFNNIDRIV 122 Query: 127 FVGKDGTVYTSYTSGGEEEAKGIAASGMLNTVREAGSYGYSHWFGMEKRSYLTSNPDSPV 186 FV +G V + +G++ M + + + W+ M +T P Sbjct: 123 FVAGNGNVICTGN-------RGVSDIYMDSIEDDLSDSNLTKWYPMSDIDVMTKQKTEPH 175 Query: 187 LTLGKMVINIDTGEPLGTLFLIVREEQLSAFLQSSDPAASKAYYFVDEHRRVVAAADKSS 246 L L + ++ IDT EP+G L + ++E+ +S S +A A+ Sbjct: 176 LVLARKILQIDTHEPVGILLIYIKEKTISEIYNSKYSENMD-----------IAIAESGQ 224 Query: 247 LLQPLE-PSMAARIGDRERADRAASFSYKDDGN----LVTVSRFGRMDWELINVVSLKLL 301 ++ +E S+ ++I ++ Y + N L + G DW LI + L Sbjct: 225 IISSVETKSIFSKINLNTNPNKGNIVFYNKEKNGKEKLCSEYNIGIFDWTLITESDMNEL 284 Query: 302 TADVQQNVRLTALVGAL---CLIFSLFGASFLSRMVASPLERLTRAMRQVVSGDLRPVAA 358 +D N RL + + C S+ L++++ +PL RL R M +V GDL V+ Sbjct: 285 LSD---NFRLIKYIIIIALICSAISVICLELLAKLIVNPLRRLERDMSRVKGGDLNVVSV 341 Query: 359 ARTEDEIGTIAEAFNFMVGRVRELLKKVTEEQKRKREYELALISAQIKPHFLYNTLDTIY 418 ++DEIG + FN MV R++ LL + EQK+KREYE +LI QIKPHFLYN LD IY Sbjct: 342 YHSQDEIGVLTSVFNEMVDRIKALLNDIKTEQKQKREYEFSLIQTQIKPHFLYNALDLIY 401 Query: 419 VLNELDRNEEARDTTKALADFYRMVLNKGRELIILEKEARITDDYLAIMQIRYPDVFRYE 478 VL + R+EEA TKALADFYR+ L+ G+E+I L +E +YL I + RY D+F + Sbjct: 402 VLCSMGRSEEAGGMTKALADFYRVALSGGKEIISLREEMNGVRNYLMIQKNRYSDIFDFS 461 Query: 479 -IDIPAELSGTPIPKLSLQPLVENAIYHGLKKKGSKGFIRIQACSTGGKVLVQVTDNGIG 537 +I EL TPIPKLS++PLVENAIYHG+K G +RI KV ++V D+GIG Sbjct: 462 IEEIEEELMETPIPKLSIEPLVENAIYHGIKPAKHFGHLRIYTNPVDEKVEIRVEDDGIG 521 Query: 538 MDEERIEAIMSGYSPEEETRSIGTYSVQQRLNLYFGEPYGLTVRSV 583 + + ++ E + G SV +RL LYFG YGL + SV Sbjct: 522 SGDRELSELIG----ESKNCGFGLRSVHERLKLYFGNDYGLKLNSV 563 >B8I996.1 B8I996_CLOCE Putative sensor with HAMP domain Length = 603 Score = 276 bits (707), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 142/421 (33%), Positives = 245/421 (58%), Gaps = 6/421 (1%) Query: 183 DSPVLTLGKMVINIDTGEPLGTLFLIVREEQLSAFLQSSDPAASKAYYFVDEHRRVVAAA 242 D V + K +I +DTG LGT L ++E+ ++A ++ + +Y VD + +++ Sbjct: 183 DEDVFAIAKTIIGMDTGHVLGTAVLYLKEKDVAAIYLNNIVNENDKFYIVDNQKNIISTQ 242 Query: 243 DKSSLLQPLEPSMAARIGDRERADRAASFSY----KDDGNLVTVSRFGRMDWELINVVSL 298 DKS L + + + +G + D + + S D L+TV F ++DW++++V+ L Sbjct: 243 DKSELYRKFDEELY--LGKYKLEDISDTKSLIRNIGDKKVLITVQNFDKLDWKVVSVIPL 300 Query: 299 KLLTADVQQNVRLTALVGALCLIFSLFGASFLSRMVASPLERLTRAMRQVVSGDLRPVAA 358 +T + ++ +L + G CLI + + LS ++ P+ +L M+++ SG+L+ A Sbjct: 301 DEITYENKKMTQLILIFGVTCLICAFVASYLLSYTISKPILKLVNIMKEIKSGNLKLRAD 360 Query: 359 ARTEDEIGTIAEAFNFMVGRVRELLKKVTEEQKRKREYELALISAQIKPHFLYNTLDTIY 418 + EIG + + FN ++ ++ L++ + EQ+ KRE E L+ +QIKPHFLYNT++TI Sbjct: 361 LNVKGEIGMLGDGFNSLMDKINVLVEHIYTEQRLKRENEFKLLQSQIKPHFLYNTIETII 420 Query: 419 VLNELDRNEEARDTTKALADFYRMVLNKGRELIILEKEARITDDYLAIMQIRYPDVFRYE 478 +L+ + A T K LA FYR+ L+KG ++I + E + D+YL+I ++RY + Y Sbjct: 421 SFIKLNLKDNAMLTAKYLAGFYRISLSKGNDIITIRDEMNLIDNYLSIQKMRYVEYLDYR 480 Query: 479 IDIPAELSGTPIPKLSLQPLVENAIYHGLKKKGSKGFIRIQACSTGGKVLVQVTDNGIGM 538 ++ E+ IPKL+LQPLVEN+IYHGLK+K +G + I+ G++ ++V D+G+GM Sbjct: 481 LEFEEEILKYQIPKLTLQPLVENSIYHGLKQKEDRGILIIKGEFENGEIKIEVFDDGVGM 540 Query: 539 DEERIEAIMSGYSPEEETRSIGTYSVQQRLNLYFGEPYGLTVRSVVDEGTVVELSLPMLG 598 EE I +++ +++ G YSV RL L +G+ YGL++ S E T V L LP + Sbjct: 541 SEENINRVLNRLINGQKSNDFGIYSVNSRLKLLYGDEYGLSIESKESEFTRVTLRLPAID 600 Query: 599 T 599 T Sbjct: 601 T 601 >B1DAS7.1 B1DAS7_9BACL Integral membrane sensor signal transduction histidine kinase Length = 598 Score = 267 bits (682), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 174/574 (30%), Positives = 309/574 (53%), Gaps = 42/574 (7%) Query: 45 RSLIERTTRNVADESQLILSRTDYILRSAETAANIMVTNI---NRLYESY------PAVQ 95 +++I++ T N + E LI + +L S E + I+ ++ N LY Y A++ Sbjct: 42 KAIIDKATNNSSRELVLIKNNLQTLLSSIEDYSKILASDYRLQNALYYDYLLNNEPNAIK 101 Query: 96 AVPLEQFRFANL-MQSRLSIDLSIFREVDAAVFVGKDGTVYTSYTSGGEEEAKGIAASGM 154 P+E NL M LS +S E + + K ++ TS + G Sbjct: 102 --PVEGLN--NLSMNKTLSETISNIVEPNTKI---KAVSILTS--------NQHWVDVGF 146 Query: 155 LNTVREAGSYGYSH----------WFGMEKRSYLTSNPDSPVLTLGKMVINIDTGEPLGT 204 + A +GY + W G+ K +L D+ V + K VI+ DTG+ +G Sbjct: 147 ADNAYAARLFGYGYGADDRTYLPIWTGLIKFRFLYEGDDN-VFAVSKTVIHKDTGKTIGR 205 Query: 205 LFLIVREEQLSAFLQSSDPAASKAYYFVDEHRRVVAAADKSSLLQPLEPSMAARIGDRER 264 +FL V+E +++ + + +Y VD R+++A +K+ L + + + + I D Sbjct: 206 IFLYVKETTIASIYEEGKKKGGE-FYIVDADGRIISAQNKAMLYRDFKEAASISIPDD-- 262 Query: 265 ADRAASFSYKDDGN--LVTVSRFGRMDWELINVVSLKLLTADVQQNVRLTALVGALCLIF 322 + ASF+ L+ RF + W +++ +++ +T++ ++ +L +GA CL+ Sbjct: 263 -GKDASFTQGSGSEEMLILTHRFEPLQWTIVSAIAMNEITSERKEINQLIIGIGAACLLL 321 Query: 323 SLFGASFLSRMVASPLERLTRAMRQVVSGDLRPVAAARTEDEIGTIAEAFNFMVGRVREL 382 +L + LSR + SP+ RL + MR++ +G ++ ++ ++ DEIG ++E FN ++ R+ L Sbjct: 322 ALMVSFQLSRSITSPIFRLAKTMREIRTGKMQVRSSYQSTDEIGYLSEGFNNLMDRIEAL 381 Query: 383 LKKVTEEQKRKREYELALISAQIKPHFLYNTLDTIYVLNELDRNEEARDTTKALADFYRM 442 + + E+Q+ K E E L+ +Q+KPHFLYNT++TI L +L ++A + +A+FY++ Sbjct: 382 MAENVEKQRTKAEIEFKLLQSQVKPHFLYNTVETIISLIKLGLGKQAITAAQYMANFYKI 441 Query: 443 VLNKGRELIILEKEARITDDYLAIMQIRYPDVFRYEIDIPAELSGTPIPKLSLQPLVENA 502 L+KG ++I + +E R+T+ YL I Q+RY + Y +DI ++ IPKL+LQP+VENA Sbjct: 442 SLSKGNDIISVGEEMRLTESYLEIQQLRYVEYMAYTMDIDDDILTYSIPKLTLQPIVENA 501 Query: 503 IYHGLKKKGSKGFIRIQACSTGGKVLVQVTDNGIGMDEERIEAIMSGYSPEEETRSIGTY 562 IYHGLK K KG +RI +G + +++ DNG GM +++ +AIM+ E+ G Sbjct: 502 IYHGLKLKQEKGIVRITGRRSGNHIEIEIYDNGAGMHKDQAKAIMAESGVPSESGGFGIR 561 Query: 563 SVQQRLNLYFGEPYGLTVRSVVDEGTVVELSLPM 596 SV R+ + +G+ YGL V S T + + LP+ Sbjct: 562 SVSNRIRMLYGDRYGLQVESESGVYTKIIIVLPL 595 >A7VQH7.1 A7VQH7_9CLOT Putative uncharacterized protein Length = 602 Score = 245 bits (626), Expect = 8e-63, Method: Compositional matrix adjust. Identities = 142/431 (32%), Positives = 237/431 (54%), Gaps = 18/431 (4%) Query: 178 LTSNPDSPVLTLGKMVINIDTGEPLGTLFLIVREEQLSAFLQSSDPAASK-AYYFVDEHR 236 + +NP P + + K V+++D +G + V E +A + + PA ++ ++Y ++E+ Sbjct: 168 IPNNPTIPKMVVSKSVVDLDNLATIGYVAFFVNESSFAAIFEENMPADTQTSFYVLNENN 227 Query: 237 RVVAAADKSSLLQPLEPSMAARIGDR------ERADRAASFSYKDDGNLVTVSRFGRMDW 290 V+++++K L + S+ I + E + S L T + +W Sbjct: 228 IVLSSSEKE--LIGTDFSVGEHISEENYRQLCENGNMILSGGTGSTDILYTSKMYEGTNW 285 Query: 291 ELINVVSLKLLTADVQQNVRLTALVGALCLIFSLFGASFLSRMVASPLERLTRAMRQVVS 350 +IN VSL L + R T ++G L + +L + ++S ++ P+ L+ AM +V Sbjct: 286 RVINAVSLNSLLQGQEAVNRFTLIIGILACVITLVLSFWVSYTISKPIHTLSNAMARVSK 345 Query: 351 GDLRPVAAARTEDEIGTIAEAFNFMVGRVRELLKKVTEEQKRKREYELALISAQIKPHFL 410 GDL ++DE+ + FN + +VR LL +V ++Q+ K +Y+L LI +Q+KPHFL Sbjct: 346 GDLNQTVITHSKDEMAILYTGFNNLTKKVRALLDEVYQKQEEKNQYQLQLIQSQVKPHFL 405 Query: 411 YNTLDTIYVLNELDRNEEARDTTKALADFYRMVLNKGRELIILEKEARITDDYLAIMQIR 470 YNTL+TI L +LD NE A + ALA FYR+ LN G ++I ++ E + YL I ++R Sbjct: 406 YNTLETIKSLVDLDLNETASEAISALAVFYRISLNNGNDIISIQNELELCRQYLYIQKLR 465 Query: 471 YPDVFRYEIDIPAELSGT---PIPKLSLQPLVENAIYHGLKKKGSKGFIRIQACSTGGKV 527 Y + Y I+ E GT I KL+LQP++ENAIYHG+K+K +KG I IQ + + Sbjct: 466 YQEYLDYRIE---ECEGTENWCISKLTLQPILENAIYHGIKEKQTKGLIVIQLKNLEDHL 522 Query: 528 LVQVTDNGIGMDEERIEAIMSGY---SPEEETRSIGTYSVQQRLNLYFGEPYGLTVRSVV 584 + V DNG+GMD E ++ + + + RS G SV +R+ L FG+ +G+ + SV+ Sbjct: 523 IFSVIDNGVGMDSETLKNLQNSLRDSCENDHLRSFGLSSVNRRIQLLFGKEFGIRIESVL 582 Query: 585 DEGTVVELSLP 595 T V L++P Sbjct: 583 HHYTKVILTIP 593 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,183,593,743 Number of extensions: 128474777 Number of successful extensions: 398649 Number of sequences better than 1.0e-05: 2288 Number of HSP's gapped: 396866 Number of HSP's successfully gapped: 2288 Length of query: 612 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 470 Effective length of database: 1,722,912,073 Effective search space: 809768674310 Effective search space used: 809768674310 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)