BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0586.0021.p (379 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KIG1.1 B3KIG1_9BACI 1-deoxy-D-xylulose 5-phosphate reductoisom... 561 e-158 B1DM61.1 B1DM61_9BACL 1-deoxy-D-xylulose 5-phosphate reductoisom... 483 e-134 C5D9C1.1 C5D9C1_9BACI 1-deoxy-D-xylulose 5-phosphate reductoisom... 431 e-119 C1PG72.1 C1PG72_BACCO 1-deoxy-D-xylulose 5-phosphate reductoisom... 427 e-118 A6CSY1.1 A6CSY1_9BACI 1-deoxy-D-xylulose 5-phosphate reductoisom... 427 e-118 >B3KIG1.1 B3KIG1_9BACI 1-deoxy-D-xylulose 5-phosphate reductoisomerase EC=1.1.1.267 Length = 385 Score = 561 bits (1445), Expect = e-158, Method: Compositional matrix adjust. Identities = 275/379 (72%), Positives = 313/379 (82%) Query: 1 LKKISILGSTGSIGTQTLDVIAMHPDAFEVDGLSAGSNTALLLEQVRRFKPRRVSVSTKE 60 +KKIS+LGSTGSIGTQTLDV+ MH + F+++GL+AGSN LLL+QV+ F PR+VSV+TKE Sbjct: 7 MKKISVLGSTGSIGTQTLDVVRMHREQFQIEGLAAGSNKELLLQQVQEFSPRKVSVATKE 66 Query: 61 LAEEIRSSLPPGVELFSGNEGMVEIAAGGEADTVVTAVMGSVGLRSTLAAIEAGRHIGLA 120 LA+ +R LP G E+F G+EG++EIAA +A+ VVTAV+GS+GL STLAAI G+ IGLA Sbjct: 67 LADSLRHDLPAGTEVFHGHEGLIEIAAATDAELVVTAVVGSLGLSSTLAAINEGKTIGLA 126 Query: 121 NKETLVTAGHLVTELAERKGVQLLPVDSEHSAIFQCLNGENREDIACITLTASGGSFRDY 180 NKETLVTAGHLVT A KGV+LLP+DSEHSAIFQCLNGE EDI ITLTASGGSFRDY Sbjct: 127 NKETLVTAGHLVTAQAAAKGVKLLPIDSEHSAIFQCLNGERHEDIERITLTASGGSFRDY 186 Query: 181 TRDQLKHVTVADALRHPNWSMGAKITIDSATMVNKGLEVIEAHWLFGLPYEQIQVLLHPE 240 TRDQL +VTV DAL+HPNWSMGAKITIDSATMVNKGLEVIEAHWL+G+PY+ I VLLHPE Sbjct: 187 TRDQLVNVTVEDALKHPNWSMGAKITIDSATMVNKGLEVIEAHWLYGIPYDNISVLLHPE 246 Query: 241 SIIHSYVEFRDSSIIAQLGNPDMRVPIQYALTYPDRWASPAKRLSLAEAQRLTFREMDYA 300 SIIHS+VEFRDSSIIAQLGNPDMRVPIQYALTYP+RW+SPA RLSLAEA +L FREMD Sbjct: 247 SIIHSFVEFRDSSIIAQLGNPDMRVPIQYALTYPERWSSPAPRLSLAEAGKLHFREMDLE 306 Query: 301 RFPALKLAIECGKXXXXXXXXXXXXXEIAVARFLRDEIPFLRIEEIIEEVLQHHELAAHP 360 RFP L+LA ECGK EIAVARFLR EI FLRIEEIIEEVL H P Sbjct: 307 RFPCLRLAYECGKMGGTAPTVFNAANEIAVARFLRGEISFLRIEEIIEEVLHSHHNVPEP 366 Query: 361 NLEQIEDCDRAARELAGKL 379 LE IE+ DR ARE+A +L Sbjct: 367 ALETIEENDRIAREIASRL 385 >B1DM61.1 B1DM61_9BACL 1-deoxy-D-xylulose 5-phosphate reductoisomerase EC=1.1.1.267 Length = 433 Score = 483 bits (1242), Expect = e-134, Method: Compositional matrix adjust. Identities = 237/377 (62%), Positives = 293/377 (77%) Query: 1 LKKISILGSTGSIGTQTLDVIAMHPDAFEVDGLSAGSNTALLLEQVRRFKPRRVSVSTKE 60 +KKI+ILGSTGSIGTQTLDVIA PD ++V GLSAG+N LL+EQ ++F+P V ++ KE Sbjct: 55 MKKITILGSTGSIGTQTLDVIANDPDRYQVVGLSAGNNLQLLIEQAKQFRPSVVCLANKE 114 Query: 61 LAEEIRSSLPPGVELFSGNEGMVEIAAGGEADTVVTAVMGSVGLRSTLAAIEAGRHIGLA 120 LAE+ + LP G ++ G EG+VEIAA +AD VVTA++GS GL +TLAAIEAG+ I LA Sbjct: 115 LAEQAKPELPSGTQVLYGEEGLVEIAANNDADVVVTAIVGSRGLPATLAAIEAGKTIALA 174 Query: 121 NKETLVTAGHLVTELAERKGVQLLPVDSEHSAIFQCLNGENREDIACITLTASGGSFRDY 180 NKETLVTAGH+V E A +KGV ++PVDSEHSAIFQCLNGE+ + + +TLTASGGSFRD Sbjct: 175 NKETLVTAGHIVMERARQKGVSIIPVDSEHSAIFQCLNGEDPKALQQLTLTASGGSFRDR 234 Query: 181 TRDQLKHVTVADALRHPNWSMGAKITIDSATMVNKGLEVIEAHWLFGLPYEQIQVLLHPE 240 TR+QL+ V+VA+AL HPNWSMGAKITIDSATMVNKGLEVIEA WLF + Y+QI+VL+HPE Sbjct: 235 TREQLEGVSVAEALNHPNWSMGAKITIDSATMVNKGLEVIEARWLFDVTYDQIKVLIHPE 294 Query: 241 SIIHSYVEFRDSSIIAQLGNPDMRVPIQYALTYPDRWASPAKRLSLAEAQRLTFREMDYA 300 SIIHS+VEF D+S+IAQLG PDMRVPIQYALTYP+R +P RL LA +L FREMD+A Sbjct: 295 SIIHSFVEFSDNSVIAQLGMPDMRVPIQYALTYPNRLPTPTGRLDLAAIGKLHFREMDFA 354 Query: 301 RFPALKLAIECGKXXXXXXXXXXXXXEIAVARFLRDEIPFLRIEEIIEEVLQHHELAAHP 360 R+P LKLA +CG+ E+AVARFL EI FL IE ++E VL+ H + A Sbjct: 355 RYPCLKLAFDCGRAGDSAPTVFNAANEVAVARFLNGEIDFLGIERVLERVLERHSVTAVN 414 Query: 361 NLEQIEDCDRAARELAG 377 +L+ I + D AR+ A Sbjct: 415 DLQAIAEIDAWARKEAA 431 >C5D9C1.1 C5D9C1_9BACI 1-deoxy-D-xylulose 5-phosphate reductoisomerase EC=1.1.1.267 Length = 381 Score = 431 bits (1109), Expect = e-119, Method: Compositional matrix adjust. Identities = 223/374 (59%), Positives = 266/374 (71%), Gaps = 1/374 (0%) Query: 1 LKKISILGSTGSIGTQTLDVIAMHPDAFEVDGLSAGSNTALLLEQVRRFKPRRVSVSTKE 60 +K ISILG++GSIGTQTLD+I HPD F++ +S G N + + F PR V+V+ + Sbjct: 1 MKYISILGASGSIGTQTLDIIRSHPDEFQLTAISIGKNVDMARAIIEEFAPRLVAVAEAD 60 Query: 61 LAEEIRSSLPPGVELFSGNEGMVEIAAGGEADTVVTAVMGSVGLRSTLAAIEAGRHIGLA 120 E++RS V++ G EG++E AA E D VVTAV+GSVGL TL AIEAG+ I LA Sbjct: 61 AYEKLRSEYAGKVKIVFGEEGLIEAAAFPETDIVVTAVVGSVGLVPTLRAIEAGKTIALA 120 Query: 121 NKETLVTAGHLVTELAERKGVQLLPVDSEHSAIFQCLNGENREDIACITLTASGGSFRDY 180 NKETLVTAGH+VT A++ GV LLPVDSEHSAIFQCL GE R + I LTASGGSFRD Sbjct: 121 NKETLVTAGHIVTAAAKKHGVSLLPVDSEHSAIFQCLQGEKRNRVEKIILTASGGSFRDK 180 Query: 181 TRDQLKHVTVADALRHPNWSMGAKITIDSATMVNKGLEVIEAHWLFGLPYEQIQVLLHPE 240 TR++LK+VTV +ALRHPNWSMGAKITIDSATM+NKGLEVIEAHWLF LPYEQI VLLH E Sbjct: 181 TREELKNVTVEEALRHPNWSMGAKITIDSATMMNKGLEVIEAHWLFELPYEQIDVLLHRE 240 Query: 241 SIIHSYVEFRDSSIIAQLGNPDMRVPIQYALTYPDRWA-SPAKRLSLAEAQRLTFREMDY 299 SIIHS V+FRD+S+IAQLG PDM VPIQYALTYP+R + AK L LAE L F +D+ Sbjct: 241 SIIHSLVQFRDTSVIAQLGTPDMHVPIQYALTYPERLPLANAKPLDLAEISTLHFERVDF 300 Query: 300 ARFPALKLAIECGKXXXXXXXXXXXXXEIAVARFLRDEIPFLRIEEIIEEVLQHHELAAH 359 RF L+LA E GK E AV+ FL+ I FL IEE IE L+ HE Sbjct: 301 ERFRCLQLAYEAGKAGGSLPTVLNAANEEAVSAFLQGRIAFLTIEEYIERALERHEFVNE 360 Query: 360 PNLEQIEDCDRAAR 373 P+LE+I + D R Sbjct: 361 PSLEEIREIDAETR 374 >C1PG72.1 C1PG72_BACCO 1-deoxy-D-xylulose 5-phosphate reductoisomerase EC=1.1.1.267 Length = 381 Score = 427 bits (1099), Expect = e-118, Method: Compositional matrix adjust. Identities = 217/380 (57%), Positives = 268/380 (70%), Gaps = 1/380 (0%) Query: 1 LKKISILGSTGSIGTQTLDVIAMHPDAFEVDGLSAGSNTALLLEQVRRFKPRRVSVSTKE 60 +K+IS+LG+TGSIGTQTLDVI HP+AF + SAG N L + + F P VSV+ KE Sbjct: 1 MKQISLLGATGSIGTQTLDVIRNHPEAFRLAAFSAGRNLNLTRKIISEFHPALVSVADKE 60 Query: 61 LAEEIRSSLPPGVELFSGNEGMVEIAAGGEADTVVTAVMGSVGLRSTLAAIEAGRHIGLA 120 +++ + G +GMVE A E+D +V AV+GSVGL TL AI AG+ + +A Sbjct: 61 DCARLKTEFGDSPVVLYGEKGMVETAVYAESDILVNAVLGSVGLLPTLEAIRAGKTVAIA 120 Query: 121 NKETLVTAGHLVTELAERKGVQLLPVDSEHSAIFQCLNGENREDIACITLTASGGSFRDY 180 NKETLVTAGHLV + A R ++LP+DSEHSAIFQCL GENR++I + +TASGGSFRDY Sbjct: 121 NKETLVTAGHLVMDAARRAETEILPIDSEHSAIFQCLQGENRDEIERLIITASGGSFRDY 180 Query: 181 TRDQLKHVTVADALRHPNWSMGAKITIDSATMVNKGLEVIEAHWLFGLPYEQIQVLLHPE 240 TR+QL+ VTV DAL HPNWSMGAKIT+DSATM+NKGLEVIEAHWLFGLP+E+I +LH E Sbjct: 181 TREQLETVTVKDALNHPNWSMGAKITVDSATMMNKGLEVIEAHWLFGLPFEKIDTILHRE 240 Query: 241 SIIHSYVEFRDSSIIAQLGNPDMRVPIQYALTYPDRWASP-AKRLSLAEAQRLTFREMDY 299 SIIHS VEFRDSS+ AQLG PDMR+PIQYAL +P R P AKRL LAE RL F +MD Sbjct: 241 SIIHSLVEFRDSSVKAQLGMPDMRIPIQYALGFPKRLPLPDAKRLDLAEIGRLHFEKMDE 300 Query: 300 ARFPALKLAIECGKXXXXXXXXXXXXXEIAVARFLRDEIPFLRIEEIIEEVLQHHELAAH 359 RF LKLA E GK E+AV FL+++I FL+I+++IE+ L H + H Sbjct: 301 ERFYCLKLAYEAGKAGGSMPAVLNAANEVAVHAFLQEKISFLQIDQLIEKALARHNVIIH 360 Query: 360 PNLEQIEDCDRAARELAGKL 379 P+LE I DR R+ L Sbjct: 361 PDLETIWAVDRETRDYVASL 380 >A6CSY1.1 A6CSY1_9BACI 1-deoxy-D-xylulose 5-phosphate reductoisomerase EC=1.1.1.267 Length = 377 Score = 427 bits (1098), Expect = e-118, Method: Compositional matrix adjust. Identities = 214/370 (57%), Positives = 263/370 (71%), Gaps = 1/370 (0%) Query: 7 LGSTGSIGTQTLDVIAMHPDAFEVDGLSAGSNTALLLEQVRRFKPRRVSVSTKELAEEIR 66 +G+TGSIG QTLDVI H D F++ +SAG N A + + F+P+ VSV KE A ++ Sbjct: 1 MGATGSIGLQTLDVIREHEDEFDLTAVSAGRNIAETKKIINEFRPKVVSVQLKEDALSLQ 60 Query: 67 SSLPPGVELFSGNEGMVEIAAGGEADTVVTAVMGSVGLRSTLAAIEAGRHIGLANKETLV 126 + LPPG ++ G EG++E+A ++D +V AV+GSVGL TL AIE+G+ I +ANKETLV Sbjct: 61 NDLPPGTKVLWGEEGLLEVACHQDSDILVNAVLGSVGLYPTLQAIESGKTIAIANKETLV 120 Query: 127 TAGHLVTELAERKGVQLLPVDSEHSAIFQCLNGENREDIACITLTASGGSFRDYTRDQLK 186 TAGH+V + A + GV LLPVDSEHSAIFQCL GE+ + I + +TASGGSFRD TRD+L+ Sbjct: 121 TAGHIVMDAARKNGVSLLPVDSEHSAIFQCLQGEDHKTIDSLIITASGGSFRDRTRDELE 180 Query: 187 HVTVADALRHPNWSMGAKITIDSATMVNKGLEVIEAHWLFGLPYEQIQVLLHPESIIHSY 246 VTV +AL HPNWSMGAKITIDSATM+NKGLEVIEAHWLFG+PY I+VLLH ESIIHS Sbjct: 181 GVTVDEALNHPNWSMGAKITIDSATMMNKGLEVIEAHWLFGIPYNDIKVLLHRESIIHSM 240 Query: 247 VEFRDSSIIAQLGNPDMRVPIQYALTYPDRWA-SPAKRLSLAEAQRLTFREMDYARFPAL 305 VEF DSS++AQLG PDMRVPIQYALTYPDR+ RL+LAE +L F EMD+ RF L Sbjct: 241 VEFHDSSVMAQLGTPDMRVPIQYALTYPDRFERHQGSRLNLAEIGKLHFEEMDFERFRCL 300 Query: 306 KLAIECGKXXXXXXXXXXXXXEIAVARFLRDEIPFLRIEEIIEEVLQHHELAAHPNLEQI 365 + + E GK E AVARFL EI FL+IE +IE L HEL P+L+ I Sbjct: 301 RFSFEAGKAGGSMPAVLNAANEAAVARFLNGEISFLQIESLIERALDKHELIKQPDLDTI 360 Query: 366 EDCDRAAREL 375 D R Sbjct: 361 RTIDAETRRF 370 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.134 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,051,274,622 Number of extensions: 78535863 Number of successful extensions: 229739 Number of sequences better than 1.0e-05: 1350 Number of HSP's gapped: 226942 Number of HSP's successfully gapped: 1353 Length of query: 379 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 242 Effective length of database: 1,770,017,148 Effective search space: 428344149816 Effective search space used: 428344149816 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 132 (55.5 bits)