BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0584.0055.p (165 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B0KAI7.1 B0KAI7_THEP3 Signal peptidase I EC=3.4.21.89 161 2e-38 B0K0Z4.1 B0K0Z4_THEPX Signal peptidase I EC=3.4.21.89 161 2e-38 B7R892.1 B7R892_9THEO Signal peptidase I EC=3.4.21.89 (Fragment) 155 7e-37 Q8RDJ6.1 Q8RDJ6_THETN Signal peptidase I 155 9e-37 B9MK77.1 B9MK77_ANATD Signal peptidase I EC=3.4.21.89 151 2e-35 >B0KAI7.1 B0KAI7_THEP3 Signal peptidase I EC=3.4.21.89 Length = 176 Score = 161 bits (407), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 78/162 (48%), Positives = 112/162 (69%), Gaps = 3/162 (1%) Query: 1 MKKFLKQWVPSIAIGIVLSLFIRTYVAEAMRVPTGSMIPTIQINDRLVVEKMLW-LTSLK 59 +KK + W+ +IA+ +++LFIRTYV E + VPTGSM+ TIQIND+ +V K ++ +K Sbjct: 5 IKKEILSWIFTIALAFLIALFIRTYVFELVDVPTGSMLNTIQINDKFIVNKFIYRFEPVK 64 Query: 60 HGDIVVFNPPVPGDEQKKYVKRLMGLPGDTLEIKDGALYRNGEQVDEPYLQEKMNYRFGP 119 GDIVVF P D + +VKR++G+ GD +EIK+G L RNG+ V EPY++E M FGP Sbjct: 65 RGDIVVFR--FPDDPKVNFVKRVIGIGGDVIEIKNGQLIRNGKVVKEPYIKEPMKGNFGP 122 Query: 120 VTVPADHYFFLGDNRNTSYDAHLWSTPFVAKDKLIGKVLLDV 161 VP HYF LGDNRN S D+ W +V+KD+++GK++ + Sbjct: 123 YVVPPGHYFMLGDNRNESMDSRFWQHKYVSKDQILGKIVFRI 164 >B0K0Z4.1 B0K0Z4_THEPX Signal peptidase I EC=3.4.21.89 Length = 176 Score = 161 bits (407), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 78/162 (48%), Positives = 112/162 (69%), Gaps = 3/162 (1%) Query: 1 MKKFLKQWVPSIAIGIVLSLFIRTYVAEAMRVPTGSMIPTIQINDRLVVEKMLW-LTSLK 59 +KK + W+ +IA+ +++LFIRTYV E + VPTGSM+ TIQIND+ +V K ++ +K Sbjct: 5 IKKEILSWIFTIALAFLIALFIRTYVFELVDVPTGSMLNTIQINDKFIVNKFIYRFEPVK 64 Query: 60 HGDIVVFNPPVPGDEQKKYVKRLMGLPGDTLEIKDGALYRNGEQVDEPYLQEKMNYRFGP 119 GDIVVF P D + +VKR++G+ GD +EIK+G L RNG+ V EPY++E M FGP Sbjct: 65 RGDIVVFR--FPDDPKVNFVKRVIGIGGDVIEIKNGQLIRNGKVVKEPYIKEPMKGNFGP 122 Query: 120 VTVPADHYFFLGDNRNTSYDAHLWSTPFVAKDKLIGKVLLDV 161 VP HYF LGDNRN S D+ W +V+KD+++GK++ + Sbjct: 123 YVVPPGHYFMLGDNRNESMDSRFWQHKYVSKDQILGKIVFRI 164 >B7R892.1 B7R892_9THEO Signal peptidase I EC=3.4.21.89 (Fragment) Length = 163 Score = 155 bits (393), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 75/154 (48%), Positives = 105/154 (68%), Gaps = 3/154 (1%) Query: 7 QWVPSIAIGIVLSLFIRTYVAEAMRVPTGSMIPTIQINDRLVVEKMLW-LTSLKHGDIVV 65 W+ +I + ++LFIRTYV E + VPTGSM+ TI IND+ +V K ++ +K GDIVV Sbjct: 11 SWIFTILLAFAIALFIRTYVFELVDVPTGSMMDTIHINDKFIVNKFIYRFEPVKRGDIVV 70 Query: 66 FNPPVPGDEQKKYVKRLMGLPGDTLEIKDGALYRNGEQVDEPYLQEKMNYRFGPVTVPAD 125 F P + + +VKR++G+ GD +EIKDG L RNG+ V+EPY++E M FGP VP Sbjct: 71 FR--FPDNPKVNFVKRVIGIGGDVIEIKDGKLIRNGKVVNEPYVKEPMKGNFGPYVVPPG 128 Query: 126 HYFFLGDNRNTSYDAHLWSTPFVAKDKLIGKVLL 159 HYF LGDNRN S D+ W +V+KD+++GKV+ Sbjct: 129 HYFMLGDNRNESMDSRFWQHKYVSKDQILGKVVF 162 >Q8RDJ6.1 Q8RDJ6_THETN Signal peptidase I Length = 176 Score = 155 bits (393), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 75/156 (48%), Positives = 106/156 (67%), Gaps = 3/156 (1%) Query: 7 QWVPSIAIGIVLSLFIRTYVAEAMRVPTGSMIPTIQINDRLVVEKMLW-LTSLKHGDIVV 65 W+ +I + ++LFIRTYV E + VPTGSM+ TI IND+ +V K ++ +K GDIVV Sbjct: 11 SWIFTILLAFAIALFIRTYVFELVDVPTGSMMDTIHINDKFIVNKFIYRFEPVKRGDIVV 70 Query: 66 FNPPVPGDEQKKYVKRLMGLPGDTLEIKDGALYRNGEQVDEPYLQEKMNYRFGPVTVPAD 125 F P + + +VKR++G+ GD +EIKDG L RNG+ V+EPY++E M FGP VP Sbjct: 71 FR--FPDNPKVNFVKRVIGIGGDVIEIKDGKLIRNGKVVNEPYVKEPMKGNFGPYVVPPG 128 Query: 126 HYFFLGDNRNTSYDAHLWSTPFVAKDKLIGKVLLDV 161 HYF LGDNRN S D+ W +V+KD+++GKV+ + Sbjct: 129 HYFMLGDNRNESMDSRFWQHKYVSKDQILGKVVFRI 164 >B9MK77.1 B9MK77_ANATD Signal peptidase I EC=3.4.21.89 Length = 185 Score = 151 bits (382), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 78/158 (49%), Positives = 105/158 (66%), Gaps = 5/158 (3%) Query: 7 QWVPSIAIGIVLSLFIRTYVAEAMRVPTGSMIPTIQINDRLVVEKM---LWLTSLKHGDI 63 +W+ I ++++L +RTYV + VPTGSM+ TIQ+NDRL V K+ L + +K GDI Sbjct: 20 EWILWIGGAVLIALILRTYVFSLVIVPTGSMLNTIQLNDRLFVYKLGYVLHIEDVKRGDI 79 Query: 64 VVFNPPVPGDEQKKYVKRLMGLPGDTLEIKDGALYRNGEQVDEPYLQEKMNYRFGPVTVP 123 VVF P D + YVKR++GLPGDT+EIKDG LY NG +E YL+E M FGP VP Sbjct: 80 VVFK--YPDDRKTLYVKRVIGLPGDTIEIKDGVLYINGRVYEENYLKEPMVGSFGPYKVP 137 Query: 124 ADHYFFLGDNRNTSYDAHLWSTPFVAKDKLIGKVLLDV 161 HYF +GDNRN S+D+ W +V +D ++GKV+ V Sbjct: 138 PGHYFMMGDNRNDSHDSRFWEHKYVPRDDILGKVVFRV 175 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.322 0.141 0.431 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,108,399,366 Number of extensions: 47725903 Number of successful extensions: 101147 Number of sequences better than 1.0e-05: 2145 Number of HSP's gapped: 98345 Number of HSP's successfully gapped: 2157 Length of query: 165 Length of database: 3,060,696,203 Length adjustment: 125 Effective length of query: 40 Effective length of database: 1,883,069,328 Effective search space: 75322773120 Effective search space used: 75322773120 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 125 (52.8 bits)