BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0584.0038.p (202 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A4F8L5.1 A4F8L5_SACEN Transcriptional regulator, TetR family 114 6e-24 Q0RRC8.1 Q0RRC8_FRAAA Putative tetR-family transcriptional regul... 100 5e-20 B5G957.1 B5G957_9ACTO TetR-family transcriptional regulator 100 1e-19 A4FFN2.1 A4FFN2_SACEN TetR-family transcriptional regulator 98 5e-19 C2A3T6.1 C2A3T6_THECU Transcriptional regulator, COG1309 96 2e-18 >A4F8L5.1 A4F8L5_SACEN Transcriptional regulator, TetR family Length = 212 Score = 114 bits (284), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 78/195 (40%), Positives = 99/195 (50%), Gaps = 4/195 (2%) Query: 7 MKTEKSGLRERKKDETRRTLIEIALNLAIERGVGQVRVEDIAAAANVSLRTFNNYFPSKE 66 M T GLRERKK TR+ L A+ LA+ERG+ V V+DIAAAA VS RTFNNYF SK Sbjct: 1 MVTRAPGLRERKKLHTRQALSWAAVRLAVERGLENVLVDDIAAAAGVSARTFNNYFSSKA 60 Query: 67 AAIIGNAYQRSEKIAVALADRPPGEALKDSLRAAVL---AGFSEPADRQWLAHMILLRDD 123 AI RS + RP EAL ++ AVL AG + W+A + L+ + Sbjct: 61 EAIAARHLDRSRRAVAEFRARPREEALWTAISHAVLSQYAGDPSGSTPDWVAGVRLMISE 120 Query: 124 PALIGAQRKAEIEFERNLAKVIAERTKKDLTRDIYPTXXXXXXXXXXXXXVFFWTSSTPG 183 PAL G +AE E A+V+ ERT D D+YP + W S P Sbjct: 121 PALRGEFLRAETLAEEEFAEVVGERTGTDPGWDLYPRLVAAAVGAAGRVAIHRWLSVNPP 180 Query: 184 GPTLHEILDEAISQL 198 G L +L A+ Q+ Sbjct: 181 G-LLEPLLSNALDQI 194 >Q0RRC8.1 Q0RRC8_FRAAA Putative tetR-family transcriptional regulator Length = 228 Score = 100 bits (250), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 72/191 (37%), Positives = 96/191 (50%), Gaps = 5/191 (2%) Query: 13 GLRERKKDETRRTLIEIALNLAIERGVGQVRVEDIAAAANVSLRTFNNYFPSKEAAIIGN 72 GLRERKK TRR L A+ L ERG+ V V++IAAAA VS RTF NYFP+K+ AI+G Sbjct: 29 GLRERKKLRTRRALRMAAIRLVAERGLDGVSVDEIAAAAEVSTRTFFNYFPTKDDAIVGI 88 Query: 73 AYQRSEKIAVALADRPPGEALKDSLRAAVLAGFSEPADRQ---WLAHMILLRDDPALIGA 129 + +I AL RP GE ++RA +L + A Q W A + ++R P L+ A Sbjct: 89 DPEDIREITEALVARPLGEEPLAAVRAVMLQRAALIAPEQADLWRARLAIIRRHPHLMTA 148 Query: 130 QRKAEIEFERNLAKVIAERTKKDLTRDIYPTXXXXXXXXXXXXXVFFWTSSTPGGPTLHE 189 + +E LA+ + R D RD YP W S PG P L + Sbjct: 149 SAASWSSYENALAEAVGSRCGLDPARDPYPAVLVAAVLAIVRILSLRWQES-PGAP-LAD 206 Query: 190 ILDEAISQLGH 200 +L +A L Sbjct: 207 LLGQAFDSLSR 217 >B5G957.1 B5G957_9ACTO TetR-family transcriptional regulator Length = 217 Score = 99.8 bits (247), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 67/143 (46%), Positives = 81/143 (56%), Gaps = 2/143 (1%) Query: 7 MKTEKSGLRERKKDETRRTLIEIALNLAIERGVGQVRVEDIAAAANVSLRTFNNYFPSKE 66 M T GLRERKK TR L E AL LA+ERG QVRVEDIA AA VS RT+NNYF S+E Sbjct: 1 MTTPPPGLRERKKQATREALREAALRLAVERGPEQVRVEDIAEAAGVSARTYNNYFASRE 60 Query: 67 AAIIGNAY-QRSEKIAVALADRPPGEALKDSLRAAVLAGFSEPADRQWLAHMILLRDDPA 125 AI+ R +IA A+ RP G L D++ AV ++ +R A ++LL PA Sbjct: 61 QAIVSAVTADREARIAAAVTARPAGARLADAVTEAVAEQYTRTGERAERA-LLLLTTRPA 119 Query: 126 LIGAQRKAEIEFERNLAKVIAER 148 L A E L V+AER Sbjct: 120 LREAFLDTTAGIEPPLTAVLAER 142 >A4FFN2.1 A4FFN2_SACEN TetR-family transcriptional regulator Length = 206 Score = 97.8 bits (242), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 71/181 (39%), Positives = 95/181 (52%), Gaps = 7/181 (3%) Query: 11 KSGLRERKKDETRRTLIEIALNLAIERGVGQVRVEDIAAAANVSLRTFNNYFPSKEAAII 70 ++GLRERKK +TR L A+ L++ERG G V +EDIAAAA+VS+RTF NYF SK AI Sbjct: 6 RAGLRERKKRQTRLALSTAAIRLSVERGAGNVTIEDIAAAADVSVRTFRNYFSSKAEAIA 65 Query: 71 GNAYQRSEKIAVALADRPPGEALKDSLRAAVLAGFS--EP-----ADRQWLAHMILLRDD 123 G R IA L RP E L D++ AV+A F+ +P A R+ + + L+ D Sbjct: 66 GMHLDRMLAIADDLRGRPAEEPLWDAITEAVIAHFAPGQPEADHDAQRKRVDAIRLMLTD 125 Query: 124 PALIGAQRKAEIEFERNLAKVIAERTKKDLTRDIYPTXXXXXXXXXXXXXVFFWTSSTPG 183 P+L G +A +A +AERT D +D+YP W PG Sbjct: 126 PSLQGELARANDAARTAVAAAVAERTGTDAEQDLYPKLVAAAVGSATAVATEHWLQCEPG 185 Query: 184 G 184 Sbjct: 186 A 186 >C2A3T6.1 C2A3T6_THECU Transcriptional regulator, COG1309 Length = 197 Score = 96.3 bits (238), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 74/194 (38%), Positives = 95/194 (48%), Gaps = 10/194 (5%) Query: 7 MKTEKSGLRERKKDETRRTLIEIALNLAIERGVGQVRVEDIAAAANVSLRTFNNYFPSKE 66 MKT GLRERKK TR+ L + A+ LAIE G+ +V VE IA AA VS RTF+NYF KE Sbjct: 1 MKT-MPGLRERKKAATRQALHDAAMRLAIEHGLDKVTVEAIADAAGVSRRTFSNYFAGKE 59 Query: 67 AAIIGNAYQRSEKIAVALADRPPGEALKDSLRAAV---LAGFSEPADRQWLAHMILLRDD 123 A++ QR I + A RPP E +LR AV D +W L + Sbjct: 60 DALLYGDEQRMRAILESFAARPPDEPSWTALRNAVDDYYRSLGRRPDPEWSMRARLAKRH 119 Query: 124 PALIGAQRKAEIEFERNLAKVIAERTKKDLTRD-IYPTXXXXXXXXXXXXXVFFWTSSTP 182 P+L Q E+NL +IAER + L D + P V WT + P Sbjct: 120 PSLAARQMANYAAAEQNLTALIAER--EGLPPDALRPRVMAAAFLSSVRIAVQMWTDTHP 177 Query: 183 GGP---TLHEILDE 193 P +HE++DE Sbjct: 178 PRPLQEIVHEVMDE 191 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.133 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,073,292,793 Number of extensions: 37828827 Number of successful extensions: 112982 Number of sequences better than 1.0e-05: 266 Number of HSP's gapped: 113072 Number of HSP's successfully gapped: 266 Length of query: 202 Length of database: 3,060,696,203 Length adjustment: 129 Effective length of query: 73 Effective length of database: 1,845,385,268 Effective search space: 134713124564 Effective search space used: 134713124564 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 128 (53.9 bits)