BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0584.0001.p (501 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C3A807.1 C3A807_BACMY Beta-lactamase 565 e-159 C2X0L6.1 C2X0L6_BACCE Beta-lactamase 557 e-157 Q6HGK6.1 Q6HGK6_BACHK Beta-lactamase EC=3.5.2.6 553 e-155 C2YTT3.1 C2YTT3_BACCE Beta-lactamase 551 e-155 B3Z447.1 B3Z447_BACCE Beta-lactamase family protein 551 e-155 >C3A807.1 C3A807_BACMY Beta-lactamase Length = 516 Score = 565 bits (1457), Expect = e-159, Method: Compositional matrix adjust. Identities = 272/499 (54%), Positives = 355/499 (71%), Gaps = 5/499 (1%) Query: 3 RKEKTIFFRGLGLSMMIATSLTILWGFTPHMNAESAQPSTAGSIEEFKQLLDRKVPQWQE 62 RK+ +I + + L +MI +T FT + AES T SIE+FK+ LD +VP+W+E Sbjct: 7 RKKASIICKSI-LCLMICIFITNEAWFTNVVRAESGTL-TDRSIEDFKKKLDEQVPKWKE 64 Query: 63 TYGVPGVAVGVIHNGKVAYTLNYGVADTKSHQPVDKDTLFQAGSISKSLTAWGILHLVDQ 122 YGVPGVA+G++H G++AYTLNYG D K+ + V DTLFQAGSISKSLT WGILHLVD+ Sbjct: 65 NYGVPGVAIGIVHEGRIAYTLNYGYVDKKTKKAVSDDTLFQAGSISKSLTVWGILHLVDE 124 Query: 123 GRLSLDDPAAKYLTRWKLPDSKFDPSQVTIRRLLSHTAGLPAHRGYLGTAPGKKLPALEE 182 GRLSLD+P KYLT+WKLP+S+F+ ++VTIRRLLSHTAGL AH+GYLG APGK L ++EE Sbjct: 125 GRLSLDNPVGKYLTKWKLPNSEFNNNEVTIRRLLSHTAGLSAHKGYLGVAPGKNLNSIEE 184 Query: 183 SLSGAGWSNDPVRVAAAPGTQEVYSGAGYTLLQLVIEEVTGQPFEQYMDEQVLKPLGMKH 242 SLSG W N+ V V PG++ +YSG GYT+LQLVIEEVTG PF++YM+EQ++KPLGMK Sbjct: 185 SLSGKVWLNEQVEVTNKPGSETIYSGGGYTILQLVIEEVTGIPFDRYMEEQIMKPLGMKS 244 Query: 243 STFAATTGSPFMSTGYGYFGQALPDYQFTEKAAAGLSTTSADLMTLIIDSMNGRNGQLPV 302 S+F + +S YGYFG+ LP YQFTE+AAAGL T D+MTLI+ SM+ N Sbjct: 245 SSFLQRPENHNLSKAYGYFGEELPSYQFTEQAAAGLKTNVTDMMTLILASMDTNNKG--- 301 Query: 303 NQVAAKPLIQEMQTPVLTDSGLGIFTRTLPDGQVMLYHPGDNRGFHSFYGFVPESGDGLA 362 N V + EMQ PVL ++GLGIF + L + +LYH GDNRG+HSFYGF+P + DGL Sbjct: 302 NGVIKSERVTEMQKPVLGENGLGIFEKKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGLV 361 Query: 363 VLTNSENGIDLRQDIYNAWVQSLTGSVPDGADALAAGRQTNAYITQGLAAALGLYLVIFA 422 +LTN E GIDLRQDIY+AW++ TG +P +LA R+ N+ + + A LGLYL++F Sbjct: 362 ILTNGEGGIDLRQDIYHAWMEYETGKLPKSYFSLAEQRKNNSITSIVIGATLGLYLLLFV 421 Query: 423 VRLRKRRRVFITKHSQQPFIRLGIRVVLLTATGTLLFLVSYSWSILGLQSGLKNIVLVVF 482 +RL K RR FI KH ++P+IRL +RV LL T L+F +Y W + L SG +++ Sbjct: 422 IRLYKGRRTFIFKHEKKPYIRLVVRVFLLIITAILVFCAAYLWRVFSLNSGNTINFILIM 481 Query: 483 AWHLILLAAGFFPKTKIRK 501 AW + LL +GFFPK + K Sbjct: 482 AWIITLLISGFFPKVRSNK 500 >C2X0L6.1 C2X0L6_BACCE Beta-lactamase Length = 530 Score = 557 bits (1436), Expect = e-157, Method: Compositional matrix adjust. Identities = 269/501 (53%), Positives = 351/501 (70%), Gaps = 4/501 (0%) Query: 1 MKRKEKTIFFRGLGLSMMIATSLTILWGFTPHMNAESAQPSTAGSIEEFKQLLDRKVPQW 60 MK ++K L +MI +T FT + AES T SIE+FK+ +D +VP+W Sbjct: 18 MKNRQKASIICKSILCLMICIFITNEVWFTNVVRAESG-TLTDRSIEDFKKKMDEQVPKW 76 Query: 61 QETYGVPGVAVGVIHNGKVAYTLNYGVADTKSHQPVDKDTLFQAGSISKSLTAWGILHLV 120 QE Y VPGVA+G++H G++AYTLNYG D K+ + V DTLFQAGSISKSLTAWGILHLV Sbjct: 77 QENYEVPGVAIGIVHEGRIAYTLNYGYVDKKTKKAVSDDTLFQAGSISKSLTAWGILHLV 136 Query: 121 DQGRLSLDDPAAKYLTRWKLPDSKFDPSQVTIRRLLSHTAGLPAHRGYLGTAPGKKLPAL 180 D+GRLSLDDP KYLT+WKLP+S+F+ ++VTIRRLLSHTAGL AH+GYLG APGK L ++ Sbjct: 137 DEGRLSLDDPVGKYLTKWKLPNSEFNNNEVTIRRLLSHTAGLSAHKGYLGVAPGKHLDSI 196 Query: 181 EESLSGAGWSNDPVRVAAAPGTQEVYSGAGYTLLQLVIEEVTGQPFEQYMDEQVLKPLGM 240 EESLSG GW N+PV V PG++ +YSG GYT+LQLVIEEVTG PF++YM+EQ++KPLG+ Sbjct: 197 EESLSGKGWLNEPVEVTNKPGSETIYSGGGYTILQLVIEEVTGIPFDRYMEEQIMKPLGI 256 Query: 241 KHSTFAATTGSPFMSTGYGYFGQALPDYQFTEKAAAGLSTTSADLMTLIIDSMNGRNGQL 300 K S+F + +S YGYFG+ LP YQFTE+AAAGL T D+MTLI+ SM+ N Sbjct: 257 KSSSFLQRPENHNLSKAYGYFGEELPSYQFTEQAAAGLKTNVTDMMTLILASMDENNKG- 315 Query: 301 PVNQVAAKPLIQEMQTPVLTDSGLGIFTRTLPDGQVMLYHPGDNRGFHSFYGFVPESGDG 360 N V ++EMQ VL ++GLGIF + L + +LYH GDNRG+HSFYGF+P + DG Sbjct: 316 --NGVIKSEHVEEMQKLVLGENGLGIFEKKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDG 373 Query: 361 LAVLTNSENGIDLRQDIYNAWVQSLTGSVPDGADALAAGRQTNAYITQGLAAALGLYLVI 420 L +LTN E GIDLRQDIY+AW++ TG +P+ +LA R+ N+ + + A LGLYL++ Sbjct: 374 LVILTNGEGGIDLRQDIYHAWIEYETGKLPESYFSLAEQRKNNSITSIVIGATLGLYLLL 433 Query: 421 FAVRLRKRRRVFITKHSQQPFIRLGIRVVLLTATGTLLFLVSYSWSILGLQSGLKNIVLV 480 F +RL K RR FI K ++ +I L +R LL T L+F +Y W + L SG ++ Sbjct: 434 FVIRLYKGRRTFIFKQEKRSYIGLVVRTFLLIITAILVFCAAYLWRVFSLNSGNTINFIL 493 Query: 481 VFAWHLILLAAGFFPKTKIRK 501 + W + LL +GFFPK K K Sbjct: 494 IMVWIITLLISGFFPKIKSNK 514 >Q6HGK6.1 Q6HGK6_BACHK Beta-lactamase EC=3.5.2.6 Length = 513 Score = 553 bits (1425), Expect = e-155, Method: Compositional matrix adjust. Identities = 263/473 (55%), Positives = 341/473 (72%), Gaps = 4/473 (0%) Query: 29 FTPHMNAESAQPSTAGSIEEFKQLLDRKVPQWQETYGVPGVAVGVIHNGKVAYTLNYGVA 88 FT + AES T SIE+FK+ LD +VP+WQ Y VPGVA+G++H G++AYTLNYG Sbjct: 29 FTNVVRAESGML-TDRSIEDFKKKLDEQVPKWQGDYEVPGVAIGIVHEGRIAYTLNYGYV 87 Query: 89 DTKSHQPVDKDTLFQAGSISKSLTAWGILHLVDQGRLSLDDPAAKYLTRWKLPDSKFDPS 148 D + + V DTLFQAGSISKSLTAWGILHLVD+GRLSLDDP KYLT+WKLP+S+F+ + Sbjct: 88 DKMTKKAVSDDTLFQAGSISKSLTAWGILHLVDEGRLSLDDPVGKYLTKWKLPNSEFNNN 147 Query: 149 QVTIRRLLSHTAGLPAHRGYLGTAPGKKLPALEESLSGAGWSNDPVRVAAAPGTQEVYSG 208 ++TIRRLLSHTAGL AH+GYLG APGK L ++EESLSG GW N+PV V PG++ +YSG Sbjct: 148 EITIRRLLSHTAGLSAHKGYLGVAPGKHLDSIEESLSGKGWLNEPVEVTNKPGSETIYSG 207 Query: 209 AGYTLLQLVIEEVTGQPFEQYMDEQVLKPLGMKHSTFAATTGSPFMSTGYGYFGQALPDY 268 GYT+LQLVIEEVTG PF++YM+EQ++KPLGMK S+F + +S YGYFG+ LP Y Sbjct: 208 GGYTILQLVIEEVTGIPFDRYMEEQIMKPLGMKSSSFLQRPENHNLSKAYGYFGEELPSY 267 Query: 269 QFTEKAAAGLSTTSADLMTLIIDSMNGRNGQLPVNQVAAKPLIQEMQTPVLTDSGLGIFT 328 QFTE+AAAGL T D+MTLI+ SM+ N N V ++EMQ PVL ++GLGIF Sbjct: 268 QFTEQAAAGLKTNVIDMMTLILASMDANNKG---NGVIKSERVEEMQKPVLGENGLGIFE 324 Query: 329 RTLPDGQVMLYHPGDNRGFHSFYGFVPESGDGLAVLTNSENGIDLRQDIYNAWVQSLTGS 388 + L + +LYH GDNRG+HSFYGF+P + DGL +LTN E GIDLRQDIY+AW++ TG Sbjct: 325 KKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGLVILTNGEGGIDLRQDIYHAWIEYETGK 384 Query: 389 VPDGADALAAGRQTNAYITQGLAAALGLYLVIFAVRLRKRRRVFITKHSQQPFIRLGIRV 448 +P+ +LA R+TN + + AALG+YL++F +RL K RR FI K ++ +I L +R Sbjct: 385 LPESYFSLAEQRKTNFITSIVIGAALGIYLLLFVIRLYKGRRTFIFKQEKKSYIGLVVRT 444 Query: 449 VLLTATGTLLFLVSYSWSILGLQSGLKNIVLVVFAWHLILLAAGFFPKTKIRK 501 LL T L+F +Y W + L SG +++ AW + LL +GFFP+ K K Sbjct: 445 FLLVVTAVLIFCAAYLWRVFSLNSGNTINFILIMAWIITLLISGFFPEIKSNK 497 >C2YTT3.1 C2YTT3_BACCE Beta-lactamase Length = 513 Score = 551 bits (1419), Expect = e-155, Method: Compositional matrix adjust. Identities = 261/473 (55%), Positives = 339/473 (71%), Gaps = 4/473 (0%) Query: 29 FTPHMNAESAQPSTAGSIEEFKQLLDRKVPQWQETYGVPGVAVGVIHNGKVAYTLNYGVA 88 FT + AES T SIE+FK+ LD +VP+WQE Y VPGVA+G++H G++AYTLNYG Sbjct: 29 FTNVVRAESGTL-TDRSIEDFKKKLDEQVPKWQENYEVPGVAIGIVHEGRIAYTLNYGYV 87 Query: 89 DTKSHQPVDKDTLFQAGSISKSLTAWGILHLVDQGRLSLDDPAAKYLTRWKLPDSKFDPS 148 D K+ + V DTLFQAGSISKSLTAWGILHLVD+GRLSLDDP KYLT+WKLP+S+F+ + Sbjct: 88 DKKTKKAVSDDTLFQAGSISKSLTAWGILHLVDEGRLSLDDPVGKYLTKWKLPNSEFNNN 147 Query: 149 QVTIRRLLSHTAGLPAHRGYLGTAPGKKLPALEESLSGAGWSNDPVRVAAAPGTQEVYSG 208 +VTIRRLLSHTAGL AH+GYLG APGK L ++EESLSG GW N+PV V PG++ +YSG Sbjct: 148 EVTIRRLLSHTAGLSAHKGYLGVAPGKHLDSIEESLSGKGWFNEPVEVTNKPGSETIYSG 207 Query: 209 AGYTLLQLVIEEVTGQPFEQYMDEQVLKPLGMKHSTFAATTGSPFMSTGYGYFGQALPDY 268 GYT+LQLV+EEVTG PF++YM+EQ++KPLGMK S+F + +S YGYFG+ LP Y Sbjct: 208 GGYTILQLVMEEVTGIPFDRYMEEQIMKPLGMKSSSFLQRPENHNLSKAYGYFGEELPSY 267 Query: 269 QFTEKAAAGLSTTSADLMTLIIDSMNGRNGQLPVNQVAAKPLIQEMQTPVLTDSGLGIFT 328 QFTE+AAAGL T D+MTLI+ SM+ N N V + EMQ PVL + GLGIF Sbjct: 268 QFTEQAAAGLKTNVTDMMTLILASMDANN---EGNGVIKSERVTEMQKPVLGEDGLGIFE 324 Query: 329 RTLPDGQVMLYHPGDNRGFHSFYGFVPESGDGLAVLTNSENGIDLRQDIYNAWVQSLTGS 388 + L + +LYH GDNRG+HSFYGF+P + DGL +LTN E GIDLRQDIY+AW++ TG Sbjct: 325 KKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGLVILTNGEGGIDLRQDIYHAWIEHETGK 384 Query: 389 VPDGADALAAGRQTNAYITQGLAAALGLYLVIFAVRLRKRRRVFITKHSQQPFIRLGIRV 448 +P+ +LA R++N+ + + A L +YL++F +RL K RR FI K ++ +I L +R Sbjct: 385 LPESYFSLAEQRKSNSITSIVIGAILSVYLLLFVIRLYKGRRTFIFKQEKKSYIGLVVRT 444 Query: 449 VLLTATGTLLFLVSYSWSILGLQSGLKNIVLVVFAWHLILLAAGFFPKTKIRK 501 LL T L+F +Y W + L SG +++ W + LL +GFFPK + K Sbjct: 445 FLLIITAILVFCAAYLWRVFSLNSGNTINFILIMVWIITLLISGFFPKIRSNK 497 >B3Z447.1 B3Z447_BACCE Beta-lactamase family protein Length = 513 Score = 551 bits (1419), Expect = e-155, Method: Compositional matrix adjust. Identities = 261/473 (55%), Positives = 339/473 (71%), Gaps = 4/473 (0%) Query: 29 FTPHMNAESAQPSTAGSIEEFKQLLDRKVPQWQETYGVPGVAVGVIHNGKVAYTLNYGVA 88 FT + AES T SIE+FK+ LD +VP+WQE Y VPGVA+G++H G++AYTLNYG Sbjct: 29 FTNVVRAESGML-TDRSIEDFKKKLDEQVPKWQENYEVPGVAIGIVHEGRIAYTLNYGYV 87 Query: 89 DTKSHQPVDKDTLFQAGSISKSLTAWGILHLVDQGRLSLDDPAAKYLTRWKLPDSKFDPS 148 D K+ + V DTLFQAGSISK+LTAWGILHLVD+GRL LD+P KYLT+WKLP+S+F+ + Sbjct: 88 DKKAKKAVSDDTLFQAGSISKNLTAWGILHLVDEGRLLLDNPVGKYLTKWKLPNSEFNNN 147 Query: 149 QVTIRRLLSHTAGLPAHRGYLGTAPGKKLPALEESLSGAGWSNDPVRVAAAPGTQEVYSG 208 +VTIRRLLSHTAGL AH+GYLG APGK L ++EESLSG GW N+ V V PG++ +YSG Sbjct: 148 EVTIRRLLSHTAGLSAHKGYLGVAPGKHLDSIEESLSGKGWLNEAVEVTNKPGSETIYSG 207 Query: 209 AGYTLLQLVIEEVTGQPFEQYMDEQVLKPLGMKHSTFAATTGSPFMSTGYGYFGQALPDY 268 GYT+LQLVIEEVTG PF++YM+EQ++KPLGMK S+F + +S YGYFG+ LP Y Sbjct: 208 GGYTILQLVIEEVTGIPFDRYMEEQIMKPLGMKSSSFLQRLENHNLSKAYGYFGEELPSY 267 Query: 269 QFTEKAAAGLSTTSADLMTLIIDSMNGRNGQLPVNQVAAKPLIQEMQTPVLTDSGLGIFT 328 QFTE+AAAGL T D+MTLI+ SM+ N N V ++EMQ PVL ++GLGIF Sbjct: 268 QFTEQAAAGLKTNVIDMMTLILASMDANNKG---NGVIKSERVEEMQKPVLGENGLGIFE 324 Query: 329 RTLPDGQVMLYHPGDNRGFHSFYGFVPESGDGLAVLTNSENGIDLRQDIYNAWVQSLTGS 388 + L + +LYH GDNRG+HSFYGF+P + DGL +LTN E GIDLRQDIY+AW++ TG Sbjct: 325 KKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGLVILTNGEGGIDLRQDIYHAWIEYETGK 384 Query: 389 VPDGADALAAGRQTNAYITQGLAAALGLYLVIFAVRLRKRRRVFITKHSQQPFIRLGIRV 448 +P+ +LA R+TN + + A L +YL++F +RL K RR FI K ++ +I L +R Sbjct: 385 LPESYFSLAEQRKTNFITSIVIGATLSIYLLLFVIRLYKGRRTFIFKQEKKSYIGLVVRT 444 Query: 449 VLLTATGTLLFLVSYSWSILGLQSGLKNIVLVVFAWHLILLAAGFFPKTKIRK 501 LL T L+F +Y W + L SG +++ AW + LL +GFFPK K K Sbjct: 445 FLLVVTAVLIFCAAYLWRVFSLNSGNTINFILIMAWIITLLISGFFPKIKSNK 497 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,144,572,615 Number of extensions: 141718493 Number of successful extensions: 372089 Number of sequences better than 1.0e-05: 3688 Number of HSP's gapped: 366541 Number of HSP's successfully gapped: 3702 Length of query: 501 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 361 Effective length of database: 1,741,754,103 Effective search space: 628773231183 Effective search space used: 628773231183 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)