BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0580.0044.p (532 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KA50.1 B3KA50_9BACI Response regulator receiver 653 0.0 B1D769.1 B1D769_9BACL Two component transcriptional regulator, A... 249 5e-64 B3KEQ5.1 B3KEQ5_9BACI Response regulator receiver 211 2e-52 B1D7Q5.1 B1D7Q5_9BACL Two component transcriptional regulator, A... 210 4e-52 B8I997.1 B8I997_CLOCE Two component transcriptional regulator, A... 204 2e-50 >B3KA50.1 B3KA50_9BACI Response regulator receiver Length = 532 Score = 653 bits (1684), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/527 (59%), Positives = 401/527 (76%), Gaps = 1/527 (0%) Query: 1 MGATQEKYKVLLVDDEPIILRSLKVAIPWEELGLAIAGEARNGEAALQLIEETAPQIIIS 60 MG ++ K++V+LVDDEPIILRSLK AIPW+EL L + GEA++G+ AL+L E +P IIIS Sbjct: 1 MGGSEGKFRVMLVDDEPIILRSLKAAIPWDELDLEVVGEAKSGDGALKLAREVSPHIIIS 60 Query: 61 DIRMPVIDGIALMKEVLPRSSKLIFIFISGYGEFEYAREALRQGAFDYLLKPIDHDELTE 120 DIRMP +DGI LMKE+ ++ I IFISGYGEFEYAREALR+GAFDYLLKPIDHDELTE Sbjct: 61 DIRMPGMDGITLMKELKADQARRIIIFISGYGEFEYAREALREGAFDYLLKPIDHDELTE 120 Query: 121 MLTRAIARLKRQKENEQLMLSVQTLSMLARERMYAEFTLGNPRPLQHLKWLENSELEGEY 180 + RA L++Q ++Q++ S++ LS+LARERM EF GN PLQH++WLE+SELE Y Sbjct: 121 TIARAARTLEKQIADDQMLHSIKVLSLLARERMLTEFIEGNRSPLQHMQWLEDSELEHGY 180 Query: 181 FMAVVRLDNYASLTAQWSVEEKRLWLFAVRNILEEWSLENGVLSVFPFYNGEWILLFPGS 240 MAV++LD Y L WS++EKRLWLFAVRN+LEEWSL++G L+VFPF +GEW+LLFP Sbjct: 181 TMAVIQLDQYLRLNELWSMDEKRLWLFAVRNVLEEWSLQHGGLTVFPFRSGEWVLLFPNL 240 Query: 241 LGSVSKELGEQLISGIRKYSKLECSVGISRITRGIDQLSTVYPLACKALYQRFYSGQAGV 300 +++G L+ I++ +KL CSVG S GID+L T Y A +ALYQRFYSG+ GV Sbjct: 241 TKERQEDIGRDLVQLIKRNTKLSCSVGFSPSMAGIDRLGTAYETAVRALYQRFYSGEEGV 300 Query: 301 FIDE-ETAAGGSREVKYPKELELALIESIRTVDLERMLSLFDEMSAFIEAQGLPQELAER 359 F+ ++ + E KYPK LE ++ESIRT+ ER+L LFDE A+IE G +E+ ER Sbjct: 301 FLGTPDSVLETASEAKYPKHLESLMVESIRTLHKERLLELFDETKAYIEEHGFSREMTER 360 Query: 360 LIIEMIVVLYRQFEHLNLHTDWSLEGLLSRLHGLGTLSAMIAALKMEFSEWMLGSNKSAT 419 +++EM VVLYRQFEH+ + +WSLE LL LH GTL ++ +K FS+W+ S Sbjct: 361 VLLEMSVVLYRQFEHMKVLFEWSLEELLQELHASGTLQQLMDVIKSHFSKWIAESRSGQA 420 Query: 420 REDGRSVVEKSMRYIEANYHKDLSIEEVAEVADLSISHFCTLFKQISGYTFLEFVTHCRM 479 +++ ++V+ K+ YI NY KDL+IEEV+E+ADLSISHFCTLFK +GYTFLE++T CR+ Sbjct: 421 KDNVQAVMGKAKEYIAENYQKDLTIEEVSELADLSISHFCTLFKGTTGYTFLEYLTECRI 480 Query: 480 EKAKYILQNSNVKVYQVAPLVGYQDPRYFTQVFKKATGKTPTEYREE 526 EKAK IL N++VKVYQVAPLVGYQDPRYFTQVFKK TGKTP+EYREE Sbjct: 481 EKAKSILLNTDVKVYQVAPLVGYQDPRYFTQVFKKITGKTPSEYREE 527 >B1D769.1 B1D769_9BACL Two component transcriptional regulator, AraC family Length = 540 Score = 249 bits (636), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 185/552 (33%), Positives = 292/552 (52%), Gaps = 63/552 (11%) Query: 9 KVLLVDDEPIILRSLKVAIPWEELGLAIAGEARNGEAALQLIEETAPQIIISDIRMPVID 68 KVLLVDDEP I R+L+ IPWE LGL + G A+NG AL+L+E + +++ DIRMPV+D Sbjct: 4 KVLLVDDEPHITRNLEKVIPWEMLGLTVGGTAKNGVEALELLESESFDLVLCDIRMPVMD 63 Query: 69 GIALMKEVLPRSSKLIFIFISGYGEFEYAREALRQGAFDYLLKPIDHDELTEMLTRAIAR 128 G+ L++ + + ++ I +SGY +F Y R A++ G DY+LKPI +DELT ++ R +A Sbjct: 64 GLELVRHIREKGTESDIIMLSGYQDFAYTRAAIQYGVKDYVLKPIPYDELTGVIARVMAN 123 Query: 129 LKRQKENEQL--MLSVQTLSMLARERM-------YAEFTLGNPRPLQHLKWL---ENSEL 176 +RQK+ +Q + + LA E++ Y E T GN WL E EL Sbjct: 124 -QRQKKKQQSEEQQKIGRMIDLASEKVLYDILMDYTEVTSGN--------WLFTGEEQEL 174 Query: 177 EGEYFMAVVRLDNYASLTA---QWSVEEKRLWLFAVRNILEEWSLENGV-LSVFPFYNGE 232 + +Y + V+ LD + T +WS +E++LW FAV N+L E +NG+ +V +GE Sbjct: 175 DKKYVLIVLDLDVSSERTKDWREWSDKERKLWNFAVCNVLRERLQQNGLHHAVIQIRDGE 234 Query: 233 WILLF--PGSLGSVSKEL---GEQLISGIRKYSKLECSVGISRITRGIDQLSTVYPLACK 287 W +L +L K++ E L++ ++ + KL GI R + LS Y + + Sbjct: 235 WCVLIECETTLAYNLKQITLWTELLLTAVKNHVKLSLYAGIYRDYADVKALSQAYKMVQQ 294 Query: 288 ALYQRFYSGQAGVFIDEETAAGGSREVKYPKELELALIESIRTVDLERMLSLFDEMSAFI 347 + Q V+ ++ AG SRE + + LI +++ D S+ DE Sbjct: 295 GMQLTPVQEQISVYPND--CAGASREDQAFWDTSEKLIGAVKRGD----TSVVDE----- 343 Query: 348 EAQGLPQELAERLIIEMIVVLYRQFEH---LNLHTDWSLEGLLSRLH------------G 392 E + L +L +++ E + ++ H LNL + G+ SR G Sbjct: 344 ELKHLTTQL--QMMNETSLGRFKPMLHFFVLNLMRETKEMGIFSREQEDLLWLKLDRRFG 401 Query: 393 LGTLSAMIAALKMEFSEWMLGSNKSATREDGRSVVEKSMRYIEANYHKDLSIEEVAEVAD 452 + L ++I + +E + ++ RS+ E + ++ N ++DLS+EE A Sbjct: 402 IKDLLSVILQVTKAVAE----KSTDKKKQSERSMAE-AKSFLGRNLYRDLSVEEAATHVG 456 Query: 453 LSISHFCTLFKQISGYTFLEFVTHCRMEKAKYILQNSNVKVYQVAPLVGYQDPRYFTQVF 512 LS S+F LFKQ TF+E+VT RMEKAK +L ++ + Q+A VGY + RYFT+VF Sbjct: 457 LSTSYFSLLFKQTYNETFIEYVTRERMEKAKSLLADTMKSIAQIAKEVGYAERRYFTKVF 516 Query: 513 KKATGKTPTEYR 524 K TG+ PT+YR Sbjct: 517 MKYTGENPTDYR 528 >B3KEQ5.1 B3KEQ5_9BACI Response regulator receiver Length = 541 Score = 211 bits (537), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 161/552 (29%), Positives = 277/552 (50%), Gaps = 58/552 (10%) Query: 6 EKYKVLLVDDEPIILRSLKVAIPWEELGLAIAGEARNGEAALQLIEETAPQIIISDIRMP 65 E + ++DD ++ L A+ WEE G+ +AG + NGE L+LI P ++I+DIRMP Sbjct: 5 EAISLCIIDDIKSVVDGL-TAMNWEEQGIRVAGVSSNGEEGLKLISGLCPDLVITDIRMP 63 Query: 66 VIDGIALMKEVLPRSSKLIFIFISGYGEFEYAREALRQGAFDYLLKPIDHDELTEMLTRA 125 ++DG+++++ VL + I ISGY +FEYA++A++ GAFD+++KP +++ + RA Sbjct: 64 IMDGLSMLRLVLEENPSCKVILISGYADFEYAQQAVQLGAFDFVVKPFTEEDMMSAVLRA 123 Query: 126 IARLKRQKENEQLMLSVQTLSMLARERMYAEFTLGNPRPLQH-LKWLE--------NSEL 176 A + ++ +S++ + RE M A + H W E N EL Sbjct: 124 KAEVMEERSKR---ISLREMENKLRESMPALRQEYFGLLVSHRTSWEEASERWDFLNIEL 180 Query: 177 EGEYFMA-VVRLDNYASLTAQWSVEEKRLWLFAVRNILEEWSLENGVLSVFPFYNGEWIL 235 E F+ ++ +D + A+ SV+E L F++ NI++E +F + +++ Sbjct: 181 EPRGFVVMLIEIDRFREQVAEQSVKEMELIRFSLLNIMQETLAHYAHSVLFRARHDQYLA 240 Query: 236 LFPGSLGSVSKELGEQLISGIRKYSKLECSVGISRITRGIDQLSTVYPLACKAL-YQRFY 294 + S S E+ EQ I +Y+K SVG+ I L Y A +AL + F Sbjct: 241 VLNDSGPSSPIEIAEQCCRNIERYTKFTISVGVGGRVEEISGLPDSYRQAHRALSHHLFT 300 Query: 295 SGQAGVFIDEETAAGGSRE---VKYPKELELALI--ESIRTVDL---------------- 333 G A + D + GS+E ++Y EL LAL + RT ++ Sbjct: 301 EGNAAIMYD-DIHQSGSQEPLALEYKDELLLALRSGNAARTDEILSAISEALQKRISRQS 359 Query: 334 -ERMLSLFDEMSAFIEAQGLPQELAERLIIEMIVVLYRQFEHLNLHTDWSLEGLLSRLHG 392 + +LSL+DE++A + L E + I + ++F + L L +LH Sbjct: 360 PDYLLSLYDELAA-----SAIRTLYEMVTYSEIQPMIQKFRTVQGTAGLPLASLQRQLHA 414 Query: 393 LGTLSAMIAALKMEFSEWMLGSNKSATREDGRSVVEKSMRYIEANYHKDLSIEEVAEVAD 452 L T A + + + +G+ V+ ++ YI+ +D+++ E A Sbjct: 415 LCTEGAELV--------------RRNSLSEGQKVIYNAIGYIKGRLSEDITVGECAAHVH 460 Query: 453 LSISHFCTLFKQISGYTFLEFVTHCRMEKAKYILQNSNVKVYQVAPLVGYQDPRYFTQVF 512 LS S+F +LFKQ++G T +F+T R+ KA+ +L +V +VA VGY++ RYF+++F Sbjct: 461 LSASYFSSLFKQVTGMTVTQFITSERIHKARLLLVE-GAQVQEVAAAVGYEERRYFSEMF 519 Query: 513 KKATGKTPTEYR 524 KK TG+TP+E+R Sbjct: 520 KKITGQTPSEFR 531 >B1D7Q5.1 B1D7Q5_9BACL Two component transcriptional regulator, AraC family Length = 530 Score = 210 bits (534), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 149/531 (28%), Positives = 274/531 (51%), Gaps = 20/531 (3%) Query: 10 VLLVDDEPIILRSLKVAIPWEELGLAIAGEARNGEAALQLIEETAPQIIISDIRMPVIDG 69 + ++DD ++ + + IPW G+ I G A +G+ L++ E P I+++DIRMPV+DG Sbjct: 1 MCVLDDIISVIDGISLGIPWANYGIEIIGTALDGDEGLKMALELNPDILLTDIRMPVMDG 60 Query: 70 IALMKEVLPRSSKLIFIFISGYGEFEYAREALRQGAFDYLLKPIDHDELTEMLTRAIARL 129 + L + ++ +S I +SGY EF YA++A+R GAFD++ KP +++ E++ +A + Sbjct: 61 LELTRRIIEKSPACKVILLSGYTEFSYAQQAIRYGAFDFVAKPFSMEDIIEVVLKATEEI 120 Query: 130 KRQKENEQLMLSV-----QTLSMLARERMYAEFTLGNPRPLQHLKW-LENSELEGEYFMA 183 + ++ + + + ++ +L +E + KW +L+ E F+ Sbjct: 121 ELERSKHKRIYEMEARVRESKPLLRQEYFNLLIRYSSSEESARAKWDFLEIDLKREGFVV 180 Query: 184 VV-RLDNYASLTAQWSVEEKRLWLFAVRNILEEWSLENGVLSVFPFYNGEWILLFPGSLG 242 +V +D ++ + E L +A++NILEE E VF ++++ + Sbjct: 181 MVAEIDRFSKTIQTLPIGEVELTRYALQNILEETINEYTQGVVFRESMNRLVIIYNSTDQ 240 Query: 243 SVSKELGEQLISGIRKYSKLECSVGISRITRGIDQLSTVYPLACKALYQRFYSGQAGVFI 302 S L E + YS+ S+G+S T I ++ Y A AL FY+G G F Sbjct: 241 IESGALAEICCNNCALYSRHTVSIGVSLSTNLISEIHLGYQQAISALSYNFYTGGNGAFR 300 Query: 303 DEETAAGGSREVKYPKELELALIESIRTVDLERMLSLFDEM---SAFIEAQGLPQELAER 359 + Y + E L+ ++R+ + E L + ++ A I+ PQ L Sbjct: 301 YGDFGQMSQHLRTYSLDQEKELLFAVRSGNQEAALGVLQQIYEDCAKIQPLPNPQYLI-T 359 Query: 360 LIIEMIVVLYRQFEHLNLHTDWSLEGLLSRLHGLGTLSAMIAALKMEFSEWMLGSNKSAT 419 + E++ ++ R E LH + L+ L + + M + L+++ S L N Sbjct: 360 MYDELVYMVLRVLEE-KLHKE-DLQELKAEIEAHKKTDRM-SLLELQKSLEQLCMNGCVL 416 Query: 420 REDGRS-----VVEKSMRYIEANYHKDLSIEEVAEVADLSISHFCTLFKQISGYTFLEFV 474 ++ R+ ++ +++ Y++ N H DLS+ E A + LS S+F LFK+++G TFL+FV Sbjct: 417 QDKHRTTEAERIIHRAIEYMKGNLHLDLSVNECATLVHLSSSYFSNLFKKVTGQTFLQFV 476 Query: 475 THCRMEKAKYILQNSNVKVYQVAPLVGYQDPRYFTQVFKKATGKTPTEYRE 525 T+ R+++AK +L + +V +VA +GY+D RYF++VFKK TG TP+E+++ Sbjct: 477 TNERIDQAKLMLMKGH-QVQEVAADIGYEDRRYFSEVFKKNTGMTPSEFKQ 526 >B8I997.1 B8I997_CLOCE Two component transcriptional regulator, AraC family Length = 542 Score = 204 bits (519), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 146/541 (26%), Positives = 268/541 (49%), Gaps = 30/541 (5%) Query: 9 KVLLVDDEPIILRSLKVAIPWEELGLAIAGEARNGEAALQLIEETAPQIIISDIRMPVID 68 K++++DDE +LKV+IPW+E G I GEA+NG+ AL+ + + P I+I DI MP+ID Sbjct: 3 KIMIIDDEFYFREALKVSIPWKEYGFEICGEAKNGKDALERVADLNPDIMIVDINMPIID 62 Query: 69 GIALMKEVLPRSSKLIFIFISGYGEFEYAREALRQGAFDYLLKPIDHDELTEML---TRA 125 G+ ++ V + + FI ++G+ EF YA++A++ G +Y+LKP++ +EL L Sbjct: 63 GLEFIQSVKEKGIESKFIILTGHSEFNYAKQAVQLGVNNYILKPVNEEELKSSLFEIKEV 122 Query: 126 IARLKRQK-ENEQLMLSVQTLSMLARERMYAEFTLGN--PRPLQHLKWLE--NSELEGEY 180 I++ + K E E L V+ L +++ E G+ P+ + LK +E + +Y Sbjct: 123 ISKERNVKFEFEGLKQQVRDSLPLLKDKFLNELIQGSLIPKENETLKKMEYLKININSDY 182 Query: 181 FMAV-VRLDNYASLTAQWSVEEKRLWLFAVRNILEEWSLENGVLSVFPFYNGEWILLFPG 239 ++ + + LD + W EEK+LW FAV NI E E + + + + I + G Sbjct: 183 YLVITIELD--CDESTGWDNEEKQLWKFAVSNISSEIMGEKFIFDI-CYDIDDRICIIVG 239 Query: 240 SLGSVSKELGEQLI----------SGIRKYSKLECSVGISRITRGIDQLSTVYPLACKAL 289 G ++ +G+ L S I K+ ++G+ + + Y + AL Sbjct: 240 IDG--AQNIGDFLTLLESRLELIRSAICKHLDFTVTMGVGSEKTELFDIPISYKESIIAL 297 Query: 290 YQRFYSGQAGVFIDEETAAGGSREVKYPKELELALIESIRTVDLERMLSLFDEMSAFIEA 349 + G+ + + A G + + E L+ +IRT D E + L ++ + Sbjct: 298 KNKLTLGKNRIILYSLVAESGIKGTAFSGEYRNKLLMNIRTADEEEVNKLISQIFMRVRG 357 Query: 350 QGLPQELAERLIIEMIVVLYRQFEHLNLHTDWSLEG----LLSRLHGLGTLSAMIAALKM 405 + + ++ + IEM+ + LH + + G ++ + ++ M +K Sbjct: 358 ENIHHQILFVVCIEMVAACMEAIVEMGLHIEDIITGNSFNIIEEIQSKKSIDEMENWIKD 417 Query: 406 EFSEWMLGSNKSATREDGRSVVEKSMRYIEANYH-KDLSIEEVAEVADLSISHFCTLFKQ 464 F + ++ + R ++E+ YI +NY +LSI+E+A ++ +H C +FK+ Sbjct: 418 IFKHTLETIKRNKISKASR-LIEEVKNYISSNYQSSELSIDEIARNLFVNYAHLCFIFKR 476 Query: 465 ISGYTFLEFVTHCRMEKAKYILQNSNVKVYQVAPLVGYQDPRYFTQVFKKATGKTPTEYR 524 +G+T E++T R++KAK + + N + VA VGY D YF + FKK G P+++ Sbjct: 477 DTGFTINEYLTEFRIKKAKELFDSGNTLILDVASKVGYADASYFGKCFKKYYGLAPSKFI 536 Query: 525 E 525 E Sbjct: 537 E 537 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.136 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,985,687,508 Number of extensions: 118593584 Number of successful extensions: 392632 Number of sequences better than 1.0e-05: 15078 Number of HSP's gapped: 403399 Number of HSP's successfully gapped: 15623 Length of query: 532 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 391 Effective length of database: 1,732,333,088 Effective search space: 677342237408 Effective search space used: 677342237408 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)