BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0580.0015.p (265 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C2U8R0.1 C2U8R0_BACCE Hydroxyethylthiazole kinase 266 1e-69 C2SVP7.1 C2SVP7_BACCE Hydroxyethylthiazole kinase 266 1e-69 C2RHV4.1 C2RHV4_BACCE Hydroxyethylthiazole kinase 266 1e-69 Q81IG9.1 THIM_BACCR Hydroxyethylthiazole kinase EC=2.7.1.50 266 1e-69 C2W3J3.1 C2W3J3_BACCE Hydroxyethylthiazole kinase 265 3e-69 >C2U8R0.1 C2U8R0_BACCE Hydroxyethylthiazole kinase Length = 272 Score = 266 bits (681), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 133/258 (51%), Positives = 179/258 (69%), Gaps = 1/258 (0%) Query: 7 VRENNPLVHNITNIVVANFSANGLLALGASPFMADAHEEVADIAAMSGAVVLNIGTLNDY 66 VRE+NPLVHNITN+VV NF+ANGLLALGASP MA A EEVA++A+++GA+VLN+GTL Sbjct: 16 VRESNPLVHNITNVVVTNFTANGLLALGASPVMAYAKEEVAEMASIAGALVLNMGTLRPE 75 Query: 67 AIESMLLAGKAANRHNVPVVLDPVGAGATAYRTEVTHKLVSQMQITALRGNVAEVAHVVG 126 +E+MLLAGK+AN +NVPV+ DPVGAGAT+YRTEV + +++++ ++RGN AE+A+V+ Sbjct: 76 EVEAMLLAGKSANVNNVPVLFDPVGAGATSYRTEVARHIPAEIELASIRGNAAEIANVIN 135 Query: 127 ERWSIXXXXXXXXXXXXXXXXXXXXXXXXXXXIITGKEDVITNGRITYVVSNGHPVLTRV 186 ERW I +ITGKEDV+T+G T V+ NGHP+LT+V Sbjct: 136 ERWEIKGVDAGTGNGNVVSIARQAADELNTVAVITGKEDVVTDGERTIVIRNGHPILTKV 195 Query: 187 TGTGCLLSAVVGAFLXXXXXXXXXXXXXXXXFYGVAAEIAANRTRQQGVGSFQTEFLNQL 246 TGTGCLL++V+GAF+ FYGVA+E+AA +T ++G GSFQ EFLNQL Sbjct: 196 TGTGCLLTSVIGAFV-AVEKDYVKAAVAALTFYGVASELAAAKTVEKGPGSFQIEFLNQL 254 Query: 247 ALVTPEVYAERSRVQRLE 264 A T + +++ LE Sbjct: 255 ANTTSSDIEKYGKIEELE 272 >C2SVP7.1 C2SVP7_BACCE Hydroxyethylthiazole kinase Length = 272 Score = 266 bits (681), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 133/258 (51%), Positives = 179/258 (69%), Gaps = 1/258 (0%) Query: 7 VRENNPLVHNITNIVVANFSANGLLALGASPFMADAHEEVADIAAMSGAVVLNIGTLNDY 66 VRE+NPLVHNITN+VV NF+ANGLLALGASP MA A EEVA++A+++GA+VLN+GTL Sbjct: 16 VRESNPLVHNITNVVVTNFTANGLLALGASPVMAYAKEEVAEMASIAGALVLNMGTLRPE 75 Query: 67 AIESMLLAGKAANRHNVPVVLDPVGAGATAYRTEVTHKLVSQMQITALRGNVAEVAHVVG 126 +E+MLLAGK+AN +NVPV+ DPVGAGAT+YRTEV + +++++ ++RGN AE+A+V+ Sbjct: 76 EVEAMLLAGKSANVNNVPVLFDPVGAGATSYRTEVARHIPAEIELASIRGNAAEIANVIN 135 Query: 127 ERWSIXXXXXXXXXXXXXXXXXXXXXXXXXXXIITGKEDVITNGRITYVVSNGHPVLTRV 186 ERW I +ITGKEDV+T+G T V+ NGHP+LT+V Sbjct: 136 ERWEIKGVDAGTGNGNVVSIARQAADELNTVAVITGKEDVVTDGERTIVIRNGHPILTKV 195 Query: 187 TGTGCLLSAVVGAFLXXXXXXXXXXXXXXXXFYGVAAEIAANRTRQQGVGSFQTEFLNQL 246 TGTGCLL++V+GAF+ FYGVA+E+AA +T ++G GSFQ EFLNQL Sbjct: 196 TGTGCLLTSVIGAFV-AVEKDYVKAAVAALTFYGVASELAAAKTVEKGPGSFQIEFLNQL 254 Query: 247 ALVTPEVYAERSRVQRLE 264 A T + +++ LE Sbjct: 255 ANTTSSDIEKYGKIEELE 272 >C2RHV4.1 C2RHV4_BACCE Hydroxyethylthiazole kinase Length = 269 Score = 266 bits (680), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 133/258 (51%), Positives = 179/258 (69%), Gaps = 1/258 (0%) Query: 7 VRENNPLVHNITNIVVANFSANGLLALGASPFMADAHEEVADIAAMSGAVVLNIGTLNDY 66 VRE+NPLVHNITN+VV NF+ANGLLALGASP MA A EEVA++A+++GA+VLN+GTL Sbjct: 13 VRESNPLVHNITNVVVTNFTANGLLALGASPVMAYAKEEVAEMASIAGALVLNMGTLRPE 72 Query: 67 AIESMLLAGKAANRHNVPVVLDPVGAGATAYRTEVTHKLVSQMQITALRGNVAEVAHVVG 126 +E+MLLAGK+AN +NVPV+ DPVGAGAT+YRTEV + +++++ ++RGN AE+A+V+ Sbjct: 73 EVEAMLLAGKSANVNNVPVLFDPVGAGATSYRTEVARHIPAEIELASIRGNAAEIANVIN 132 Query: 127 ERWSIXXXXXXXXXXXXXXXXXXXXXXXXXXXIITGKEDVITNGRITYVVSNGHPVLTRV 186 ERW I +ITGKEDV+T+G T V+ NGHP+LT+V Sbjct: 133 ERWEIKGVDAGTGNGNVVSIARQAADELNTVAVITGKEDVVTDGERTIVIRNGHPILTKV 192 Query: 187 TGTGCLLSAVVGAFLXXXXXXXXXXXXXXXXFYGVAAEIAANRTRQQGVGSFQTEFLNQL 246 TGTGCLL++V+GAF+ FYGVA+E+AA +T ++G GSFQ EFLNQL Sbjct: 193 TGTGCLLTSVIGAFV-AVEKDYVKAAVAALTFYGVASELAAAKTVEKGPGSFQIEFLNQL 251 Query: 247 ALVTPEVYAERSRVQRLE 264 A T + +++ LE Sbjct: 252 ANTTSSDIEKYGKIEELE 269 >Q81IG9.1 THIM_BACCR Hydroxyethylthiazole kinase EC=2.7.1.50 Length = 269 Score = 266 bits (680), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 133/258 (51%), Positives = 179/258 (69%), Gaps = 1/258 (0%) Query: 7 VRENNPLVHNITNIVVANFSANGLLALGASPFMADAHEEVADIAAMSGAVVLNIGTLNDY 66 VRE+NPLVHNITN+VV NF+ANGLLALGASP MA A EEVA++A+++GA+VLN+GTL Sbjct: 13 VRESNPLVHNITNVVVTNFTANGLLALGASPVMAYAKEEVAEMASIAGALVLNMGTLRPE 72 Query: 67 AIESMLLAGKAANRHNVPVVLDPVGAGATAYRTEVTHKLVSQMQITALRGNVAEVAHVVG 126 +E+MLLAGK+AN +NVPV+ DPVGAGAT+YRTEV + +++++ ++RGN AE+A+V+ Sbjct: 73 EVEAMLLAGKSANVNNVPVLFDPVGAGATSYRTEVARHIPAEIELASIRGNAAEIANVIN 132 Query: 127 ERWSIXXXXXXXXXXXXXXXXXXXXXXXXXXXIITGKEDVITNGRITYVVSNGHPVLTRV 186 ERW I +ITGKEDV+T+G T V+ NGHP+LT+V Sbjct: 133 ERWEIKGVDAGTGNGNVVSIARQAADELNTVAVITGKEDVVTDGERTIVIRNGHPILTKV 192 Query: 187 TGTGCLLSAVVGAFLXXXXXXXXXXXXXXXXFYGVAAEIAANRTRQQGVGSFQTEFLNQL 246 TGTGCLL++V+GAF+ FYGVA+E+AA +T ++G GSFQ EFLNQL Sbjct: 193 TGTGCLLTSVIGAFV-AVEKDYVKAAVAALTFYGVASELAAAKTVEKGPGSFQIEFLNQL 251 Query: 247 ALVTPEVYAERSRVQRLE 264 A T + +++ LE Sbjct: 252 ANTTSSDIEKYGKIEELE 269 >C2W3J3.1 C2W3J3_BACCE Hydroxyethylthiazole kinase Length = 271 Score = 265 bits (677), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 132/257 (51%), Positives = 176/257 (68%), Gaps = 1/257 (0%) Query: 7 VRENNPLVHNITNIVVANFSANGLLALGASPFMADAHEEVADIAAMSGAVVLNIGTLNDY 66 VRE NPLVHNITN+VV NF+ANGLLALGASP MA A EEVA++A+++GA+VLN+GTL Sbjct: 16 VRETNPLVHNITNVVVTNFTANGLLALGASPVMAYAKEEVAEMASIAGALVLNMGTLRPE 75 Query: 67 AIESMLLAGKAANRHNVPVVLDPVGAGATAYRTEVTHKLVSQMQITALRGNVAEVAHVVG 126 +E+M++AGK+AN H+VPV+ DPVGAGAT+YRTEV + ++++ +RGN AE+A+V+ Sbjct: 76 EVEAMVIAGKSANTHHVPVLFDPVGAGATSYRTEVARHIPGEVKLAMIRGNAAEIANVIN 135 Query: 127 ERWSIXXXXXXXXXXXXXXXXXXXXXXXXXXXIITGKEDVITNGRITYVVSNGHPVLTRV 186 E+W I +ITGKEDV+T+G T+++ NGHP+LT+V Sbjct: 136 EKWEIKGVDAGAGNGDVVGIAKQAADEIDTVAVITGKEDVVTDGERTFIIRNGHPILTKV 195 Query: 187 TGTGCLLSAVVGAFLXXXXXXXXXXXXXXXXFYGVAAEIAANRTRQQGVGSFQTEFLNQL 246 TGTGCLL++V+GAF FYGVAAEIAA++T +QG GSFQ EFLNQL Sbjct: 196 TGTGCLLTSVLGAF-AAVEKDYVKAAVAALTFYGVAAEIAASKTVEQGPGSFQIEFLNQL 254 Query: 247 ALVTPEVYAERSRVQRL 263 A T A+ +Q + Sbjct: 255 ANTTANDIAQYGNIQEV 271 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.132 0.369 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,183,450,798 Number of extensions: 37165417 Number of successful extensions: 110191 Number of sequences better than 1.0e-05: 747 Number of HSP's gapped: 109321 Number of HSP's successfully gapped: 835 Length of query: 265 Length of database: 3,060,696,203 Length adjustment: 133 Effective length of query: 132 Effective length of database: 1,807,701,208 Effective search space: 238616559456 Effective search space used: 238616559456 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 130 (54.7 bits)