BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0579.0053.p (617 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1HYN0.1 B1HYN0_LYSSC Penicillin-binding protein 489 e-136 C1F0B9.1 C1F0B9_BACC3 Putative penicillin-binding protein 483 e-134 C3C4I0.1 C3C4I0_BACTU Putative uncharacterized protein 483 e-134 C3I2X4.1 C3I2X4_BACTU Putative uncharacterized protein 482 e-134 C2PH08.1 C2PH08_BACCE Putative uncharacterized protein 482 e-134 >B1HYN0.1 B1HYN0_LYSSC Penicillin-binding protein Length = 694 Score = 489 bits (1258), Expect = e-136, Method: Compositional matrix adjust. Identities = 253/589 (42%), Positives = 358/589 (60%), Gaps = 20/589 (3%) Query: 19 MKKIIAVVMSAML---IAIPI-----SGNQASA-----QPHNDTVQEKAHKLASTIVSDY 65 MKK ++ V++A L I++P SGN S + + +Q+ A + A+ ++ Y Sbjct: 1 MKKKLSGVLAATLALTISLPTGALAASGNNQSTVLVSQEVASQALQKIAAEKANLLIKSY 60 Query: 66 GVTGLQYAIMDKGKIVLSDSTGVRDKAANAPITKDTMFGIGSVSKMYVTAAAMMLADAGK 125 T +QYA++D G I++S TG D P+TKDT++GIGSVSKMY TAA M L D GK Sbjct: 61 ETTSVQYALIDNGHIIVSGQTGKNDMKGKQPLTKDTLYGIGSVSKMYATAAVMKLVDEGK 120 Query: 126 IDIDQPLVTYIKDFSMADERYKEITPRMLMNHSSGLYGSHYANSMLFDDNDTRNRDELLM 185 +D+D P+V Y+ DF M DERYK ITPRML+NHSSGL G+ Y NS LFDDNDT D LL Sbjct: 121 VDLDVPVVHYVPDFKMKDERYKRITPRMLLNHSSGLQGTGYGNSFLFDDNDTYAHDNLLQ 180 Query: 186 RLQSEHLKSKPGEYSVYCNDGFQLLEILVERVSGLSYTEFLDQKVNQPLKLTSTKTPLSA 245 +L ++ LK+ PG +SVYCN+GF L EI+VE+VSG+S+TEF+ ++ +PLKL TKTP Sbjct: 181 QLSTQSLKADPGAFSVYCNNGFTLAEIMVEKVSGMSFTEFIHERFTKPLKLNHTKTPQDK 240 Query: 246 FDREKLAKTYSPVTELALPVENANIIGTGGLYSTAEELAAFGDVLIGNRTDILSEKSAAA 305 + +K A Y P LP E+ N+IGTGG+ STAE++ F + +G ILS+K+ A Sbjct: 241 EENDKRAGLYFPTYHGQLPAESVNVIGTGGISSTAEDMIRFAQIFMGQGQGILSDKAVKA 300 Query: 306 MQSPEYRKGIWVPEETNSFNYGLGWDAVSLAPFDDYGIKALSKGGDTVMYHAALTTLPEH 365 M+ EY+KG+W + N NYGLGWD+V L PF +YGIK L+KGGDT + HA+L LPE Sbjct: 301 MEQEEYKKGMWPEDGANIINYGLGWDSVKLYPFSEYGIKGLAKGGDTGLQHASLVVLPEQ 360 Query: 366 NIXXXXXXXXXXXXYNTVFASKVLLEYLQDKGKIKEIVPDRTFEPSVKVNMPAEQLAYSG 425 + N + A+++LL L++KG IKEI P+++F VK MP + + +G Sbjct: 361 KMAVAVLTSGGSSSTNQMMATEILLAALKEKGTIKEIKPNKSFGKPVKAKMPQDIVKKAG 420 Query: 426 LYGAVGTTLNVEM-KNGEMKLPALEGGIIPPQTYVYTGNGQFKGNDGKAAISFDKQSNGK 484 YG + +++ NGE+ LPA I + YVYT NG F G + +F + NG+ Sbjct: 421 FYGNSFSHFKIKITNNGELLLPA-----ISEEKYVYTANGSFINETGTSKFNFVTEKNGR 475 Query: 485 IYFKLKAYVDFPGIGQAVMVTYEYQKLDANPLQPATKAAWEQRNHKNYYGLDEKINSLFY 544 Y ++ PG+GQ + Y +KL+ N L T AAW +R +Y ++EK +S Y Sbjct: 476 TYLVESTFITLPGLGQVAVTQYLAEKLEDNVLSKETAAAWAKREGVKFYLVNEKFSSAQY 535 Query: 545 LSPVILIRNITVDSA-NGYASGTRIVDEHTAVNAAEIPVMXXXXSGDER 592 L P++L IT D GY +G +I +TA + +IPVM + + R Sbjct: 536 LLPMMLTTQITRDEELKGYWNGRKITGPNTAAHQLQIPVMAGRDTTESR 584 >C1F0B9.1 C1F0B9_BACC3 Putative penicillin-binding protein Length = 691 Score = 483 bits (1244), Expect = e-134, Method: Compositional matrix adjust. Identities = 249/566 (43%), Positives = 345/566 (60%), Gaps = 11/566 (1%) Query: 23 IAVVMSAMLIAIPISGNQASAQPHNDTVQEKAHKLAST----IVSDYGVTGLQYAIMDKG 78 +A+ MS AI S ++A + + K+A+ + Y T +QYA++D G Sbjct: 13 LALTMSLPTGAIASSSSKAQVVSSQEVASKDLEKVAAENAALLTKSYETTSVQYALIDNG 72 Query: 79 KIVLSDSTGVRDKAANAPITKDTMFGIGSVSKMYVTAAAMMLADAGKIDIDQPLVTYIKD 138 K++LS TG D P+TKDT++GIGS SK+Y AA M L D GK+D+D P+ YI D Sbjct: 73 KLILSGQTGKNDIEGKEPLTKDTLYGIGSTSKVYTAAAVMKLVDEGKVDLDAPVARYIPD 132 Query: 139 FSMADERYKEITPRMLMNHSSGLYGSHYANSMLFDDNDTRNRDELLMRLQSEHLKSKPGE 198 F M D+RYK ITPRML+NHSSGL GS + N+ LF DND D LL +L +++LK+ PG Sbjct: 133 FKMKDKRYKRITPRMLLNHSSGLQGSTFNNAFLFKDNDVYAHDILLQQLSNQNLKADPGA 192 Query: 199 YSVYCNDGFQLLEILVERVSGLSYTEFLDQKVNQPLKLTSTKTPLSAFDREKLAKTYSPV 258 +SVYCNDGF L EILVERVSG+S+TEFL QK +PLKL T T ++ EK A YSP Sbjct: 193 FSVYCNDGFTLAEILVERVSGMSFTEFLHQKFTEPLKLNHTITSQDKWEDEKRAGLYSPT 252 Query: 259 TELALPVENANIIGTGGLYSTAEELAAFGDVLIGNRTDILSEKSAAAMQSPEYRKGIWVP 318 + LP E N+IGTGG+ STAE++ F + +G +ILS K+ AM+ EY+KG+W Sbjct: 253 YQGQLPSEMVNLIGTGGISSTAEDVVRFSQIFMGQGKEILSNKAVKAMEQEEYKKGMWPG 312 Query: 319 EETNSFNYGLGWDAVSLAPFDDYGIKALSKGGDTVMYHAALTTLPEHNIXXXXXXXXXXX 378 + N FNYGLGWD+V L PF +YGIKAL+KGGDT++ HA L LPE + Sbjct: 313 DSGNVFNYGLGWDSVKLYPFSEYGIKALTKGGDTILQHATLVVLPEQKMAAAVLSSGGSS 372 Query: 379 XYNTVFASKVLLEYLQDKGKIKEIVPDRTFEPSVKVNMPAEQLAYSGLYGAVGTTLNVEM 438 N + A+K+LL L++KG IK+I PD++F VK +P + + +G YG + +E+ Sbjct: 373 MTNQLLANKLLLARLKEKGTIKDIKPDKSFGNPVKAKVPQDVVKKAGFYGNSRSHFKIEI 432 Query: 439 -KNGEMKLPALEGGIIPPQTYVYTGNGQFKGNDGKAAISFDKQSNGKIYFKLKAYVDFPG 497 K GE+ LP P + YVYT +G F G + ++F + NGK+Y + Y PG Sbjct: 433 TKKGELFLPTK-----PEEKYVYTADGSFINEKGTSKLNFVTEKNGKVYLRESTYELSPG 487 Query: 498 IGQAVMVTYEYQKLDANPLQPATKAAWEQRNHKNYYGLDEKINSLFYLSPVILIRNITVD 557 +GQ V+ Y QKL+ N L T AAW +R +Y ++EK NS+ YL +I + N + Sbjct: 488 LGQTVLTQYLAQKLENNVLPKKTAAAWAKREGGKFYLVNEKFNSINYLGQLIPL-NTQIT 546 Query: 558 SANGYASGTRIVDEHTAVNAAEIPVM 583 + +GY G +I +TA + +IPVM Sbjct: 547 TKDGYWDGKKITGPNTATHQIQIPVM 572 >C3C4I0.1 C3C4I0_BACTU Putative uncharacterized protein Length = 691 Score = 483 bits (1242), Expect = e-134, Method: Compositional matrix adjust. Identities = 249/566 (43%), Positives = 344/566 (60%), Gaps = 11/566 (1%) Query: 23 IAVVMSAMLIAIPISGNQASAQPHNDTVQEKAHKLAST----IVSDYGVTGLQYAIMDKG 78 +A+ MS AI S ++ + + K+A+ + Y T +QYA++D G Sbjct: 13 LALTMSLPTGAIASSSSKTPVVSSQEVASKDLEKIAAENAELLTKSYETTSVQYALIDNG 72 Query: 79 KIVLSDSTGVRDKAANAPITKDTMFGIGSVSKMYVTAAAMMLADAGKIDIDQPLVTYIKD 138 K++LS TG D P+TKDT++GIGS SK+Y AA M L D GK+D+D P+ YI D Sbjct: 73 KLILSGQTGKNDIEGKEPLTKDTLYGIGSTSKVYTAAAVMKLVDEGKVDLDAPVARYIPD 132 Query: 139 FSMADERYKEITPRMLMNHSSGLYGSHYANSMLFDDNDTRNRDELLMRLQSEHLKSKPGE 198 F M D+RYK ITPRML+NHSSGL GS + NS LF DNDT D LL +L +++LK+ PG Sbjct: 133 FKMKDKRYKHITPRMLLNHSSGLQGSTFNNSFLFKDNDTYAHDILLQQLSNQNLKADPGA 192 Query: 199 YSVYCNDGFQLLEILVERVSGLSYTEFLDQKVNQPLKLTSTKTPLSAFDREKLAKTYSPV 258 +SVYCNDGF L EILVERVSG+S+TEFL QK +PLKL T T ++ EK A YSP Sbjct: 193 FSVYCNDGFTLAEILVERVSGMSFTEFLHQKFTEPLKLNHTITSQDKWEDEKRAGQYSPT 252 Query: 259 TELALPVENANIIGTGGLYSTAEELAAFGDVLIGNRTDILSEKSAAAMQSPEYRKGIWVP 318 + LP E N+IGTGG+ STAE++ F + +G +ILS K+ AM+ EY+KG+W Sbjct: 253 YQGQLPSEMVNVIGTGGISSTAEDVVRFSQIFMGQGKEILSNKAVKAMEQEEYKKGMWPG 312 Query: 319 EETNSFNYGLGWDAVSLAPFDDYGIKALSKGGDTVMYHAALTTLPEHNIXXXXXXXXXXX 378 + N FNYGLGWD+V L PF +YGIKAL+KGGDT++ HA L LPE + Sbjct: 313 DSGNMFNYGLGWDSVKLYPFSEYGIKALTKGGDTILQHATLVVLPEQKMAAAVLSSGGTS 372 Query: 379 XYNTVFASKVLLEYLQDKGKIKEIVPDRTFEPSVKVNMPAEQLAYSGLYGAVGTTLNVEM 438 N + A+K+LL L++KG IK+I PD++F VKV +P + + +G YG + +E+ Sbjct: 373 MTNQLLANKLLLARLKEKGTIKDIKPDKSFGKPVKVKVPQDVVKKAGFYGNSFSNFKIEI 432 Query: 439 -KNGEMKLPALEGGIIPPQTYVYTGNGQFKGNDGKAAISFDKQSNGKIYFKLKAYVDFPG 497 K GE+ LP P + YVYT +G F G + ++F + NGK+Y + Y PG Sbjct: 433 TKKGELFLPTK-----PEEKYVYTADGSFINEKGTSKLNFVTEKNGKVYLRESTYELSPG 487 Query: 498 IGQAVMVTYEYQKLDANPLQPATKAAWEQRNHKNYYGLDEKINSLFYLSPVILIRNITVD 557 +GQ V+ Y QKL+ N L T A W +R +Y ++EK NS+ YL ++ + N + Sbjct: 488 LGQNVLTHYLAQKLENNVLPKKTAATWAKREGGKFYLVNEKFNSMNYLGQLMPL-NTQIK 546 Query: 558 SANGYASGTRIVDEHTAVNAAEIPVM 583 +GY G +I +TA + +IPVM Sbjct: 547 IKDGYWDGKKITGPNTATHQIQIPVM 572 >C3I2X4.1 C3I2X4_BACTU Putative uncharacterized protein Length = 691 Score = 482 bits (1240), Expect = e-134, Method: Compositional matrix adjust. Identities = 247/566 (43%), Positives = 346/566 (61%), Gaps = 11/566 (1%) Query: 23 IAVVMSAMLIAIPISGNQASAQPHNDTVQEKAHKLAST----IVSDYGVTGLQYAIMDKG 78 +A+ MS AI S ++A + + K+A+ + Y T +QYA++D G Sbjct: 13 LALTMSLPTGAIASSSSKAPVVSSQEVASKDLEKIAAENAELLTKSYETTSVQYALIDNG 72 Query: 79 KIVLSDSTGVRDKAANAPITKDTMFGIGSVSKMYVTAAAMMLADAGKIDIDQPLVTYIKD 138 K++LS TG D P+TKDT++GIGS SK+Y AA M L D GK+D+D P+ YI D Sbjct: 73 KLILSGQTGKNDIEGKEPLTKDTLYGIGSTSKVYTAAAVMKLVDEGKVDLDAPVARYIPD 132 Query: 139 FSMADERYKEITPRMLMNHSSGLYGSHYANSMLFDDNDTRNRDELLMRLQSEHLKSKPGE 198 F M D+RYK ITPRML+NHSSGL GS + N+ LF DND D LL +L +++LK+ PG Sbjct: 133 FKMKDKRYKRITPRMLLNHSSGLQGSTFNNAFLFKDNDAYAHDILLQQLSNQNLKADPGA 192 Query: 199 YSVYCNDGFQLLEILVERVSGLSYTEFLDQKVNQPLKLTSTKTPLSAFDREKLAKTYSPV 258 +SVYCNDGF L EILVERVSG+S+TEFL QK +PLKL T T ++ EK A YSP Sbjct: 193 FSVYCNDGFTLAEILVERVSGMSFTEFLHQKFTEPLKLNHTITSQDKWEDEKRAGQYSPT 252 Query: 259 TELALPVENANIIGTGGLYSTAEELAAFGDVLIGNRTDILSEKSAAAMQSPEYRKGIWVP 318 + LP E N+IGTGG+ STAE++ F + +G +ILS K+ AM+ EY++G+W Sbjct: 253 YQGQLPSEMVNVIGTGGISSTAEDVVRFSQIFMGQGKEILSNKAVKAMEQEEYKRGMWPE 312 Query: 319 EETNSFNYGLGWDAVSLAPFDDYGIKALSKGGDTVMYHAALTTLPEHNIXXXXXXXXXXX 378 + N FNYGLGWD+V L PF +YGIKAL+KGGDTV+ HA L LPE + Sbjct: 313 DSENVFNYGLGWDSVKLYPFSEYGIKALTKGGDTVLQHATLVVLPEQKMAAAVLSSGGSS 372 Query: 379 XYNTVFASKVLLEYLQDKGKIKEIVPDRTFEPSVKVNMPAEQLAYSGLYGAVGTTLNVEM 438 N + A+K+LL L++KG IK+I PD++F VK +P + + +G YG + + +E+ Sbjct: 373 TTNQLLANKLLLARLKEKGTIKDIKPDKSFGKPVKAKVPQDVVKKAGFYGNIQSHFKIEI 432 Query: 439 -KNGEMKLPALEGGIIPPQTYVYTGNGQFKGNDGKAAISFDKQSNGKIYFKLKAYVDFPG 497 K GE+ LP P + YVYT +G F G + ++F + NGK+Y + Y PG Sbjct: 433 TKKGELFLPTK-----PEEKYVYTADGSFINEKGTSKLNFVTEKNGKVYLRESTYELSPG 487 Query: 498 IGQAVMVTYEYQKLDANPLQPATKAAWEQRNHKNYYGLDEKINSLFYLSPVILIRNITVD 557 +GQ V+ Y QKL+ N L T AAW +R +Y ++EK NS+ YL ++ + N + Sbjct: 488 LGQNVLTHYLAQKLENNVLPKKTVAAWAKREGGKFYLVNEKFNSMNYLGQLMPL-NTQIT 546 Query: 558 SANGYASGTRIVDEHTAVNAAEIPVM 583 +GY G +I ++A++ +IPVM Sbjct: 547 IKDGYWDGKKITGPNSAMHQIQIPVM 572 >C2PH08.1 C2PH08_BACCE Putative uncharacterized protein Length = 733 Score = 482 bits (1240), Expect = e-134, Method: Compositional matrix adjust. Identities = 249/566 (43%), Positives = 346/566 (61%), Gaps = 11/566 (1%) Query: 23 IAVVMSAMLIAIPISGNQASAQPHNDTVQEKAHKLAST----IVSDYGVTGLQYAIMDKG 78 +A+ MS AI S ++ + + K+A+ + Y T +QYA++D G Sbjct: 55 LALTMSLPTGAIASSSSKTPVVSSQEVASKDLEKIAAENAELLTKSYETTSVQYALIDNG 114 Query: 79 KIVLSDSTGVRDKAANAPITKDTMFGIGSVSKMYVTAAAMMLADAGKIDIDQPLVTYIKD 138 K++LS TG D P+TKDT+FGIGS SK+Y AA M L D GK+D+D P+ YI D Sbjct: 115 KLILSGQTGKNDIEGKEPLTKDTLFGIGSTSKVYTAAAVMKLVDEGKVDLDAPVARYIPD 174 Query: 139 FSMADERYKEITPRMLMNHSSGLYGSHYANSMLFDDNDTRNRDELLMRLQSEHLKSKPGE 198 F M D+RYK ITPRML+NHSSGL GS + N+ LF DND D LL +L +++LK+ PG Sbjct: 175 FKMKDKRYKRITPRMLLNHSSGLQGSTFNNAFLFKDNDAYAHDILLQQLSNQNLKADPGA 234 Query: 199 YSVYCNDGFQLLEILVERVSGLSYTEFLDQKVNQPLKLTSTKTPLSAFDREKLAKTYSPV 258 +SVYCNDGF L EILVERVSG+S+TEFL QK +PLKL T T ++ EK A YSP Sbjct: 235 FSVYCNDGFTLAEILVERVSGMSFTEFLHQKFTEPLKLNHTITSQDKWEDEKRAGQYSPT 294 Query: 259 TELALPVENANIIGTGGLYSTAEELAAFGDVLIGNRTDILSEKSAAAMQSPEYRKGIWVP 318 + LP E N+IGTGG+ STAE++ F + +G +ILS K+ AM+ EY+KG+W Sbjct: 295 YQGQLPSEMVNLIGTGGISSTAEDVVRFSQIFMGQGKEILSNKAVKAMEQEEYKKGMWPG 354 Query: 319 EETNSFNYGLGWDAVSLAPFDDYGIKALSKGGDTVMYHAALTTLPEHNIXXXXXXXXXXX 378 + N FNYGLGWD+V L PF +YGIKAL+KGGDT++ HA L LPE + Sbjct: 355 DSGNVFNYGLGWDSVKLYPFSEYGIKALTKGGDTILQHATLVVLPEQKMAAAVLSSGGSS 414 Query: 379 XYNTVFASKVLLEYLQDKGKIKEIVPDRTFEPSVKVNMPAEQLAYSGLYGAVGTTLNVEM 438 N + A+K+LL L++KG IK+I PD++F VK +P + + +GLYG + +E+ Sbjct: 415 MTNQLLANKLLLARLKEKGAIKDIKPDKSFGKPVKAKVPQDVVKKAGLYGNSYSDFKIEI 474 Query: 439 -KNGEMKLPALEGGIIPPQTYVYTGNGQFKGNDGKAAISFDKQSNGKIYFKLKAYVDFPG 497 K GE+ LP P + YVYT +G F G + ++F + NGK+Y + AY PG Sbjct: 475 TKKGELFLPTK-----PEEKYVYTADGSFINEKGTSKLNFVTEKNGKVYLRESAYELSPG 529 Query: 498 IGQAVMVTYEYQKLDANPLQPATKAAWEQRNHKNYYGLDEKINSLFYLSPVILIRNITVD 557 +GQ V+ Y QKL+ N L T AAW +R +Y ++EK NS+ YL ++ + N + Sbjct: 530 LGQNVLTQYLAQKLENNVLPKKTAAAWAKREGGKFYLVNEKFNSMNYLGQLMPL-NTQIT 588 Query: 558 SANGYASGTRIVDEHTAVNAAEIPVM 583 +GY G +I ++A++ +IPVM Sbjct: 589 IKDGYWDGKQITGPNSAMHQIQIPVM 614 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.315 0.133 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,569,881,058 Number of extensions: 152454462 Number of successful extensions: 357361 Number of sequences better than 1.0e-05: 2996 Number of HSP's gapped: 355134 Number of HSP's successfully gapped: 3004 Length of query: 617 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 475 Effective length of database: 1,722,912,073 Effective search space: 818383234675 Effective search space used: 818383234675 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 134 (56.2 bits)