BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0579.0003.p (191 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KD74.1 B3KD74_9BACI Regulatory protein TetR 252 1e-65 C3CHB6.1 C3CHB6_BACTU Transcriptional regulator, TetR 159 2e-37 B7JG07.1 B7JG07_BACC0 Transcriptional regulator, TetR family 154 3e-36 C3GLE0.1 C3GLE0_BACTU Transcriptional regulator, TetR 154 3e-36 C2TJ15.1 C2TJ15_BACCE Transcriptional regulator, TetR 154 3e-36 >B3KD74.1 B3KD74_9BACI Regulatory protein TetR Length = 194 Score = 252 bits (643), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 123/194 (63%), Positives = 155/194 (79%), Gaps = 3/194 (1%) Query: 1 MGRYKEFDKEAVLHKAMLVFWKKGYEAASIPDLLEAMDLSRSSLYETFGDKQTLYIEAIN 60 MGR KEFD+E VL KAM+VFW+KGYE ASIPDLL+AM+LSRSS+YETF DKQTLY EAI Sbjct: 1 MGRTKEFDREQVLRKAMIVFWEKGYEGASIPDLLQAMELSRSSMYETFQDKQTLYYEAIQ 60 Query: 61 WYKKWKQAKRDILVNATSAKSGIRQYFEIHIDSAL--DGES-PKGCLITNAAVGMDSPDE 117 YKK Q KRD++ +A SA +GIRQYFE+HI +A GE+ P GCLITNA+VG+D+ DE Sbjct: 61 QYKKMSQKKRDLMNHAPSAIAGIRQYFELHITNAFATHGEAYPNGCLITNASVGLDAMDE 120 Query: 118 QLNALIRERFDELEKSFYELLRKGQKTGEIMPEKDIKTLSYLLSNLNHSINIVSKVQGDR 177 L IR+ F ELE+ FYE L+KGQ+TGEI PEKDIK LS+LL NLNHSIN+++++Q D Sbjct: 121 PLQNTIRQSFTELEQLFYEKLKKGQETGEISPEKDIKMLSFLLLNLNHSINVMARIQSDS 180 Query: 178 SKMQQMIDMVMEML 191 +++ M++ V+E L Sbjct: 181 DQVRGMMNAVIESL 194 >C3CHB6.1 C3CHB6_BACTU Transcriptional regulator, TetR Length = 191 Score = 159 bits (401), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 73/185 (39%), Positives = 122/185 (65%) Query: 1 MGRYKEFDKEAVLHKAMLVFWKKGYEAASIPDLLEAMDLSRSSLYETFGDKQTLYIEAIN 60 MGR F+KE L+KAM +FW+KGY+A I DL+E M +SRS+LY++FGDK L+ + Sbjct: 1 MGRSISFNKEHALNKAMHLFWEKGYDATYISDLIETMGISRSTLYDSFGDKDALFKLVLE 60 Query: 61 WYKKWKQAKRDILVNATSAKSGIRQYFEIHIDSALDGESPKGCLITNAAVGMDSPDEQLN 120 YK + KR++L + + K+ ++ +F HI+ GE PKGC+ITN+++ + D + Sbjct: 61 HYKNYGSQKRNLLFSGINTKASLKSFFYQHIEKCYSGEIPKGCMITNSSLLIGQIDPAIE 120 Query: 121 ALIRERFDELEKSFYELLRKGQKTGEIMPEKDIKTLSYLLSNLNHSINIVSKVQGDRSKM 180 ++ F+ELEK F +++ +G+K GEI E D + ++Y L +LNHS+N++SK + +++ Sbjct: 121 EILINDFNELEKVFKQVIEEGKKKGEISQEVDTELVAYSLLSLNHSLNVMSKYKKEKNSA 180 Query: 181 QQMID 185 ++D Sbjct: 181 YHLVD 185 >B7JG07.1 B7JG07_BACC0 Transcriptional regulator, TetR family Length = 191 Score = 154 bits (390), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 73/185 (39%), Positives = 121/185 (65%) Query: 1 MGRYKEFDKEAVLHKAMLVFWKKGYEAASIPDLLEAMDLSRSSLYETFGDKQTLYIEAIN 60 MGR F+KE L+KAM +FW+KGY+A I DL+E M +SRS+LY++FGDK L+ + Sbjct: 1 MGRKISFNKEQALNKAMHLFWEKGYDATYISDLIETMGISRSTLYDSFGDKDALFKLVLE 60 Query: 61 WYKKWKQAKRDILVNATSAKSGIRQYFEIHIDSALDGESPKGCLITNAAVGMDSPDEQLN 120 YK + KR++L + +AK+ + +F HI+ E PKGC+ITN+++ + D + Sbjct: 61 HYKNYGSQKRNLLFSGINAKASLTSFFYQHIEKCYSDEIPKGCIITNSSLLIGKIDPAIE 120 Query: 121 ALIRERFDELEKSFYELLRKGQKTGEIMPEKDIKTLSYLLSNLNHSINIVSKVQGDRSKM 180 ++ F+ELEK F +++ +G++ GEI E D + ++Y L +LNHS+NI+SK + ++ Sbjct: 121 EILINDFNELEKVFKQVIEEGKRKGEISQEADTELVAYSLLSLNHSLNIMSKYKKEKKLA 180 Query: 181 QQMID 185 +++D Sbjct: 181 YRLVD 185 >C3GLE0.1 C3GLE0_BACTU Transcriptional regulator, TetR Length = 191 Score = 154 bits (390), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 73/185 (39%), Positives = 121/185 (65%) Query: 1 MGRYKEFDKEAVLHKAMLVFWKKGYEAASIPDLLEAMDLSRSSLYETFGDKQTLYIEAIN 60 MGR F+KE L+KAM +FW+KGY+A I DL+E M +SRS+LY++FGDK L+ + Sbjct: 1 MGRKISFNKEQALNKAMHLFWEKGYDATYISDLIETMGISRSTLYDSFGDKDALFKLVLE 60 Query: 61 WYKKWKQAKRDILVNATSAKSGIRQYFEIHIDSALDGESPKGCLITNAAVGMDSPDEQLN 120 YK + KR++L + +AK+ + +F HI+ E PKGC+ITN+++ + D + Sbjct: 61 HYKNYGSQKRNLLFSGINAKASLTSFFYQHIEKCYSDEIPKGCIITNSSLLIGKIDPAIE 120 Query: 121 ALIRERFDELEKSFYELLRKGQKTGEIMPEKDIKTLSYLLSNLNHSINIVSKVQGDRSKM 180 ++ F+ELEK F +++ +G++ GEI E D + ++Y L +LNHS+NI+SK + ++ Sbjct: 121 EILINDFNELEKVFKQVIEEGKRKGEISQEADTELVAYSLLSLNHSLNIMSKYKKEKKLA 180 Query: 181 QQMID 185 +++D Sbjct: 181 YRLVD 185 >C2TJ15.1 C2TJ15_BACCE Transcriptional regulator, TetR Length = 191 Score = 154 bits (390), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 73/185 (39%), Positives = 121/185 (65%) Query: 1 MGRYKEFDKEAVLHKAMLVFWKKGYEAASIPDLLEAMDLSRSSLYETFGDKQTLYIEAIN 60 MGR F+KE L+KAM +FW+KGY+A I DL+E M +SRS+LY++FGDK L+ + Sbjct: 1 MGRKISFNKEQALNKAMHLFWEKGYDATYISDLIETMGISRSTLYDSFGDKDALFKLVLE 60 Query: 61 WYKKWKQAKRDILVNATSAKSGIRQYFEIHIDSALDGESPKGCLITNAAVGMDSPDEQLN 120 YK + KR++L + +AK+ + +F HI+ E PKGC+ITN+++ + D + Sbjct: 61 HYKNYGSQKRNLLFSGINAKASLTSFFYQHIEKCYSDEIPKGCIITNSSLLIGKIDPAIE 120 Query: 121 ALIRERFDELEKSFYELLRKGQKTGEIMPEKDIKTLSYLLSNLNHSINIVSKVQGDRSKM 180 ++ F+ELEK F +++ +G++ GEI E D + ++Y L +LNHS+NI+SK + ++ Sbjct: 121 EILINDFNELEKVFKQVIEEGKRKGEISQEADTELVAYSLLSLNHSLNIMSKYKKEKKLA 180 Query: 181 QQMID 185 +++D Sbjct: 181 YRLVD 185 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.133 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,053,712,772 Number of extensions: 40242462 Number of successful extensions: 151739 Number of sequences better than 1.0e-05: 883 Number of HSP's gapped: 151603 Number of HSP's successfully gapped: 883 Length of query: 191 Length of database: 3,060,696,203 Length adjustment: 128 Effective length of query: 63 Effective length of database: 1,854,806,283 Effective search space: 116852795829 Effective search space used: 116852795829 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 127 (53.5 bits)