BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0574.0019.p (251 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A6CJJ6.1 A6CJJ6_9BACI Methionine aminopeptidase EC=3.4.11.18 275 2e-72 A7HTD8.1 A7HTD8_PARL1 Methionine aminopeptidase EC=3.4.11.18 275 3e-72 A6C4C2.1 A6C4C2_9PLAN Methionine aminopeptidase EC=3.4.11.18 272 2e-71 A7GVA3.1 A7GVA3_BACCN Methionine aminopeptidase EC=3.4.11.18 266 1e-69 Q3F0J6.1 Q3F0J6_BACTI Methionine aminopeptidase EC=3.4.11.18 266 2e-69 >A6CJJ6.1 A6CJJ6_9BACI Methionine aminopeptidase EC=3.4.11.18 Length = 247 Score = 275 bits (704), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 127/246 (51%), Positives = 173/246 (70%) Query: 4 MTSDTAQDLQGLKAVGHVVGYTIAEMRKRTVPGMTTAELDEVGAAVLERFGAKSAPKVTY 63 M Q+LQ +K +G +V + EM+ PGMTT ELDE+GA++ E+ GA SAPK Y Sbjct: 1 MIIKNEQELQSMKVIGRIVAFIRDEMKNAAKPGMTTKELDELGASLFEQHGAISAPKQEY 60 Query: 64 NFPGSTCISINEEVAHGIPGSRVIQAGDLVNIDVSAELNGYYGDAGASFQLPPYNEKLVH 123 +FPG TCIS+NEEVAHGIPG R+IQ GDL+NIDVS +G+Y D G SF + +EKL+ Sbjct: 61 DFPGFTCISVNEEVAHGIPGERIIQEGDLINIDVSGSKDGFYADTGISFVVGDGDEKLLD 120 Query: 124 LCRSAEETMMSVINHLRAGMKVNEIGRVMETEARKRGYNVVRNLCSHGIGRSLHEKPFEI 183 LC + +++ + + ++AG K+N IG+ + EARK GY V++NL HG+G+SLHE+P I Sbjct: 121 LCEAVKKSFDAGLKKIKAGAKLNGIGKAVHNEARKNGYTVIKNLTGHGVGKSLHEEPAHI 180 Query: 184 LPFYNPRVTTVLKEGQVITVEPFLSTGADFVEQQSDGWTLSVNDSSRVAQYEHTIIVTKG 243 + +++P +L +G VI EPF+ST A+ + Q+SDGWT D S VAQ EHTIIVTKG Sbjct: 181 MNYFDPWDNGLLADGMVIAFEPFVSTKAEEIVQESDGWTFVTEDKSSVAQIEHTIIVTKG 240 Query: 244 KPIILT 249 +PIILT Sbjct: 241 EPIILT 246 >A7HTD8.1 A7HTD8_PARL1 Methionine aminopeptidase EC=3.4.11.18 Length = 248 Score = 275 bits (703), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 127/248 (51%), Positives = 174/248 (70%) Query: 4 MTSDTAQDLQGLKAVGHVVGYTIAEMRKRTVPGMTTAELDEVGAAVLERFGAKSAPKVTY 63 MT + +L+GL+A+G +V + M PGMTT ELD++G A+LER GA+SAP++ Y Sbjct: 1 MTISSEAELEGLRAIGRIVAEVLKAMGAALEPGMTTRELDDLGRALLEREGARSAPELAY 60 Query: 64 NFPGSTCISINEEVAHGIPGSRVIQAGDLVNIDVSAELNGYYGDAGASFQLPPYNEKLVH 123 FPG+TCIS+NE++AHGIPG R+I+AGDLVNIDVSAE G++GD GASF +PP ++ + Sbjct: 61 GFPGATCISVNEQIAHGIPGERIIRAGDLVNIDVSAEKGGFFGDTGASFAVPPVRTQIEN 120 Query: 124 LCRSAEETMMSVINHLRAGMKVNEIGRVMETEARKRGYNVVRNLCSHGIGRSLHEKPFEI 183 LCR + M I +R G K+N IG +E+ A KRGY+++RNL SHGIGRSLHE+P I Sbjct: 121 LCRDGRKAMWEGIRAVRPGAKLNMIGERIESFAEKRGYSLIRNLASHGIGRSLHEEPEAI 180 Query: 184 LPFYNPRVTTVLKEGQVITVEPFLSTGADFVEQQSDGWTLSVNDSSRVAQYEHTIIVTKG 243 + +P + EG V T+EPFLS G D+ + +DGWTL + + QYEH+++VTK Sbjct: 181 STWRDPSDRRRMDEGLVFTIEPFLSMGGDYAAEAADGWTLLADPVAPTVQYEHSLVVTKN 240 Query: 244 KPIILTSA 251 P+ILT A Sbjct: 241 GPVILTLA 248 >A6C4C2.1 A6C4C2_9PLAN Methionine aminopeptidase EC=3.4.11.18 Length = 262 Score = 272 bits (695), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 131/246 (53%), Positives = 175/246 (71%) Query: 4 MTSDTAQDLQGLKAVGHVVGYTIAEMRKRTVPGMTTAELDEVGAAVLERFGAKSAPKVTY 63 +T +TA+DL+ L+ +G +V T+ EM T PG+TT ELD VG A+LE GA+SAPK+TY Sbjct: 15 VTIETAKDLRELRKIGRIVAITLQEMMACTQPGVTTGELDLVGKALLEAHGARSAPKLTY 74 Query: 64 NFPGSTCISINEEVAHGIPGSRVIQAGDLVNIDVSAELNGYYGDAGASFQLPPYNEKLVH 123 NFPG TCIS+NEE AHGIPG RVIQ GD+VNIDVSAE NGY+ D G +F +PP N Sbjct: 75 NFPGYTCISVNEEAAHGIPGKRVIQPGDVVNIDVSAEKNGYFADTGGTFVVPPGNPLKDK 134 Query: 124 LCRSAEETMMSVINHLRAGMKVNEIGRVMETEARKRGYNVVRNLCSHGIGRSLHEKPFEI 183 L S + + + RAG +N IG+ ++ A++ G+ ++RNLCSHG+GR LHE+P EI Sbjct: 135 LIASTQMALTEACHAARAGRPLNGIGKSIQKVAKQTGFRIIRNLCSHGVGRGLHEEPGEI 194 Query: 184 LPFYNPRVTTVLKEGQVITVEPFLSTGADFVEQQSDGWTLSVNDSSRVAQYEHTIIVTKG 243 ++ P T VL EG VIT+EPFLST + V + +DGWTL+ + AQ+EHT+++TKG Sbjct: 195 PGYFVPGDTRVLHEGLVITIEPFLSTKSRIVTEGNDGWTLAGEAGNLSAQFEHTLVITKG 254 Query: 244 KPIILT 249 KPI+LT Sbjct: 255 KPILLT 260 >A7GVA3.1 A7GVA3_BACCN Methionine aminopeptidase EC=3.4.11.18 Length = 250 Score = 266 bits (680), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 132/241 (54%), Positives = 167/241 (69%), Gaps = 2/241 (0%) Query: 10 QDLQGLKAVGHVVGYTIAEMRKRTVPGMTTAELDEVGAAVLERFGAKSAPKVTYNFPGST 69 QDL+GL+ +G +V EM+K+ PGMTT ELD +G VL+ GA SAP+ Y+FPG T Sbjct: 7 QDLEGLRKIGRIVALAREEMKKQAKPGMTTKELDLIGKKVLDEHGAISAPEKEYDFPGVT 66 Query: 70 CISINEEVAHGIPGSRVIQAGDLVNIDVSAELNGYYGDAGASFQLPPYNEKLVHLCRSAE 129 CIS+NEEVAHGIPG RV++ GDLVN+DVSA L+GYY D G SF L EK LC++A Sbjct: 67 CISVNEEVAHGIPGDRVLKEGDLVNVDVSAALDGYYADTGISFVLGTDEEK-EKLCQAAV 125 Query: 130 ETMMSVINHLRAGMKVNEIGRVMETEARKRGYNVVRNLCSHGIGRSLHEKPFEILPFYNP 189 + + + ++AG K N+IGR + A K GYNV++NL HGIG SLHE P IL +Y+P Sbjct: 126 DAFWAAMKKVKAGSKQNQIGRAVSNFAHKNGYNVIQNLTGHGIGLSLHEAPNHILNYYDP 185 Query: 190 RVTTVLKEGQVITVEPFLSTGAD-FVEQQSDGWTLSVNDSSRVAQYEHTIIVTKGKPIIL 248 +LK+G VI VEPF+S AD +E+ DGWT D S VAQ EHTIIVT+G+PIIL Sbjct: 186 MDNALLKDGLVIAVEPFISMKADHIIERGDDGWTFITPDKSLVAQCEHTIIVTRGEPIIL 245 Query: 249 T 249 T Sbjct: 246 T 246 >Q3F0J6.1 Q3F0J6_BACTI Methionine aminopeptidase EC=3.4.11.18 Length = 264 Score = 266 bits (679), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 130/241 (53%), Positives = 168/241 (69%), Gaps = 2/241 (0%) Query: 10 QDLQGLKAVGHVVGYTIAEMRKRTVPGMTTAELDEVGAAVLERFGAKSAPKVTYNFPGST 69 QDL+GL+ +G +V EM+K+ PGMTT ELD +G VL+ GA SAP+ Y+FPG T Sbjct: 23 QDLEGLRKIGRIVALAREEMKKQAKPGMTTKELDLIGKKVLDEHGAISAPEKEYDFPGVT 82 Query: 70 CISINEEVAHGIPGSRVIQAGDLVNIDVSAELNGYYGDAGASFQLPPYNEKLVHLCRSAE 129 CIS+NEEVAHGIPG RV++ GDLVN+DVSA L+GYY D G SF L +E LC++A Sbjct: 83 CISVNEEVAHGIPGDRVLKEGDLVNVDVSAALDGYYADTGISFVLGE-DEAKEKLCQAAV 141 Query: 130 ETMMSVINHLRAGMKVNEIGRVMETEARKRGYNVVRNLCSHGIGRSLHEKPFEILPFYNP 189 + + + ++AG K N+IGR + A K GYNV++NL HGIG SLHE P IL +Y+P Sbjct: 142 DAFWAAMKKVKAGSKQNQIGRAVSNFAHKSGYNVIQNLTGHGIGLSLHEAPNHILSYYDP 201 Query: 190 RVTTVLKEGQVITVEPFLSTGAD-FVEQQSDGWTLSVNDSSRVAQYEHTIIVTKGKPIIL 248 T+LK+G VI VEPF+S AD +E+ DGWT D S VAQ EHT++VT+G+PIIL Sbjct: 202 MDNTLLKDGLVIAVEPFISMKADHIIERGDDGWTFITPDKSLVAQCEHTVVVTRGEPIIL 261 Query: 249 T 249 T Sbjct: 262 T 262 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.133 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,428,285,093 Number of extensions: 55071399 Number of successful extensions: 156420 Number of sequences better than 1.0e-05: 2979 Number of HSP's gapped: 151466 Number of HSP's successfully gapped: 2989 Length of query: 251 Length of database: 3,060,696,203 Length adjustment: 132 Effective length of query: 119 Effective length of database: 1,817,122,223 Effective search space: 216237544537 Effective search space used: 216237544537 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 129 (54.3 bits)