BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0572.0003.p
         (174 letters)

Database: pfamseq 
           9,421,015 sequences; 3,060,696,203 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

B1D6H7.1 B1D6H7_9BACL Transcriptional regulator, TetR family          156   5e-37
A1SIP6.1 A1SIP6_NOCSJ Regulatory protein, TetR                        122   1e-26
A4AL13.1 A4AL13_9ACTN Putative uncharacterized protein                 82   3e-14
C5BVU2.1 C5BVU2_9MICO Transcriptional regulator, TetR family           70   6e-11

>B1D6H7.1 B1D6H7_9BACL Transcriptional regulator, TetR family
          Length = 212

 Score =  156 bits (395), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 77/174 (44%), Positives = 112/174 (64%)

Query: 1   MDGFIVDDVVLKANFSRRTFANYFSCKEEAVAEYFIGNASKEDRNMLLKDLPPDATPLDA 60
           MD F+V+DVV +A +SRRTFAN+FSCKEEAV        + ++   L+++L  ++TPL+ 
Sbjct: 39  MDSFVVEDVVQRAGYSRRTFANHFSCKEEAVVMGASAFNNVDEVQQLIENLTENSTPLEV 98

Query: 61  LYNLLKLQFTSEFLYKLRQFVLLANQYPSLEPYILSVFRRLQIAAQETLEQFSHGRYADG 120
           + +L++++ T+    K R+ V L+ Q+P+LEPYILS     Q  A++ L       YA G
Sbjct: 99  MEHLVRMELTAGLFKKTRELVKLSKQHPTLEPYILSALHSHQGLAEQLLLDLFEDNYAKG 158

Query: 121 YTHLLAGAVYGAFVPILDGRLNVLLPGESQEEDSGAMSFDQYLNSMFAYLHNGF 174
           Y  LL GA YGA +P+L G  N+  PG+S EE   ++  DQYL++MF YL NGF
Sbjct: 159 YIQLLVGASYGAALPMLYGNSNIRFPGQSSEESPDSIPLDQYLDNMFGYLKNGF 212


>A1SIP6.1 A1SIP6_NOCSJ Regulatory protein, TetR
          Length = 200

 Score =  122 bits (306), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 75/172 (43%), Positives = 108/172 (62%), Gaps = 3/172 (1%)

Query: 3   GFIVDDVVLKANFSRRTFANYFSCKEEAVAEYFIGNASKEDRNMLLKDLPPDATPLDALY 62
           GF+  DVV +A +SRRTFAN+FSCKEEAVA    G    +D + +L  LP D   LDAL 
Sbjct: 32  GFVTTDVVERAGYSRRTFANHFSCKEEAVASVAFGGV--DDASAILAGLPADLPLLDALL 89

Query: 63  NLLKLQFTSEFLYKLRQFVLLANQYPSLEPYILSVFRRLQIAAQETLEQFSHGRYADGYT 122
            +++ QF ++ L ++R+ + +A  YP+LEPY+L V +R++  AQE L   +  RY   Y 
Sbjct: 90  AVMRDQFAADTLVRMRELMAMARHYPTLEPYVLGVQQRMRHTAQELLGSVAGDRYPAIYV 149

Query: 123 HLLAGAVYGAFVPILDGRLNVLLPGESQEEDSGAMSFDQYLNSMFAYLHNGF 174
            LL GAVYGA +  L+G L+V L GE+ +    +M +D +L+  F YL +G 
Sbjct: 150 PLLFGAVYGAVMAALEGTLDVHLDGEN-DLSPVSMDYDSFLDLTFDYLRHGL 200


>A4AL13.1 A4AL13_9ACTN Putative uncharacterized protein
          Length = 191

 Score = 81.6 bits (200), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 55/174 (31%), Positives = 93/174 (53%), Gaps = 4/174 (2%)

Query: 1   MDGFIVDDVVLKANFSRRTFANYFSCKEEAVAEYFIGNASKEDRNMLLKDLPPDATPLDA 60
           + GF ++++ + A+ SRRT +NYF  KE+AVA   +    +    + ++    D    D 
Sbjct: 18  LGGFSLEELAVVADVSRRTVSNYFDSKEQAVAFVTLLRMREALEGLSVES---DVPLPDQ 74

Query: 61  LYNLLKLQFTSEFLYKLRQFVLLANQYPSLEPYILSVFRRLQIAAQETLEQFSHGRYADG 120
           + NLL+ QF+   +   R+   LA+  PSL+PY+  V +R    A + L +     Y   
Sbjct: 75  IDNLLRTQFSEYVITTHRRLADLASDSPSLQPYLHDVEQRGIAEATQFLRERLGPDYPPM 134

Query: 121 YTHLLAGAVYGAFVPILDGRLNVLLPGESQEEDSGAMSFDQYLNSMFAYLHNGF 174
           Y +L+ GA YGA   +LDGRL VL   +S  +    +S + +++++  YL +GF
Sbjct: 135 YAYLVVGAAYGAMSALLDGRL-VLREADSITDPLNEVSLNGFISTIADYLRHGF 187


>C5BVU2.1 C5BVU2_9MICO Transcriptional regulator, TetR family
          Length = 251

 Score = 70.1 bits (170), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 52/208 (25%), Positives = 83/208 (39%), Gaps = 40/208 (19%)

Query: 1   MDGFIVDDVVLKANFSRRTFANYFSCKEEAVAEYFIGNASK------------------- 41
           +DGF +D++      +RRTF N+F+ KEEAVA   +    +                   
Sbjct: 41  LDGFTIDELAEATGLARRTFFNHFTSKEEAVAHVVVLKVREVLAVIADSHEEHGEPEEHE 100

Query: 42  ---------------EDRNMLLKDLPPDATPLDALYNLLKLQFTSEFLYKLRQFVLLANQ 86
                            R     DL   A  L A+  + +     + L  LR F  LA +
Sbjct: 101 GDDVDDDAHVAALTCRLRTRYAGDL---AATLGAVDEVTRSLLAPDVLTTLRAFAQLAER 157

Query: 87  YPSLEPYILSVFRRLQIAAQETLEQFSHGRYADGYTHLLAGAVYGAFVPILDGRLNVLLP 146
           +P L P++ +V    +  A E L    HG   D   HL+ GAV     P++ G L ++  
Sbjct: 158 HPQLVPHLFTVENDARTQAAELLRTPEHGGLTDLQAHLVPGAVISTIAPVVGGELLLV-- 215

Query: 147 GESQEEDSGAMSFDQYLNSMFAYLHNGF 174
            E   +  GA++ D+ +  +  +L  G 
Sbjct: 216 -ELDGDAPGAITTDELVGQLITFLTRGI 242


  Database: pfamseq
    Posted date:  Aug 5, 2010  3:22 PM
  Number of letters in database: 3,060,696,203
  Number of sequences in database:  9,421,015
  
Lambda     K      H
   0.323    0.139    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 9421015
Number of Hits to DB: 1,018,664,684
Number of extensions: 38946973
Number of successful extensions: 87099
Number of sequences better than 1.0e-05: 4
Number of HSP's gapped: 87101
Number of HSP's successfully gapped: 4
Length of query: 174
Length of database: 3,060,696,203
Length adjustment: 126
Effective length of query: 48
Effective length of database: 1,873,648,313
Effective search space: 89935119024
Effective search space used: 89935119024
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 126 (53.1 bits)