BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0571.0021.p
         (614 letters)

Database: pfamseq 
           9,421,015 sequences; 3,060,696,203 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

B1D5Y0.1 B1D5Y0_9BACL Integral membrane sensor signal transducti...   469   e-130
B3KF79.1 B3KF79_9BACI Histidine kinase internal region                449   e-124
B8I948.1 B8I948_CLOCE Histidine kinase                                248   2e-63
B0K338.1 B0K338_THEPX Histidine kinase internal region                205   1e-50
A8RMQ3.1 A8RMQ3_9CLOT Putative uncharacterized protein                186   5e-45

>B1D5Y0.1 B1D5Y0_9BACL Integral membrane sensor signal transduction histidine
           kinase
          Length = 626

 Score =  469 bits (1206), Expect = e-130,   Method: Compositional matrix adjust.
 Identities = 251/590 (42%), Positives = 364/590 (61%), Gaps = 19/590 (3%)

Query: 19  KNWXXXXXXXXXXPVSIMLGTFYQRSNEVLEKEVTRTMQLTLKQAGMNLTYKLNHIRDSS 78
           + W          P +++L  +Y+RS  +L+ EV RTMQLTL+QAG NL+Y+L HI + S
Sbjct: 34  RQWLIAYCILIVFPAAVILYGYYERSAAILKNEVMRTMQLTLEQAGSNLSYRLEHIEEIS 93

Query: 79  NSVFMNQILYDNLLQKDK---ITDQLGQIRELRNLAETAQENEDIFRLRFFVEASRMYGG 135
           ++ FMN  L++ L   D    I+ QL  +++LRNL E+ Q N D+FR+R FV+ S++Y G
Sbjct: 94  DAAFMNNKLHEYLSVSDTDKLISTQLEVVKDLRNLVESVQSNSDVFRVRLFVDKSKLYAG 153

Query: 136 DRINLYPLADMDQYPWYEAVKEAGGGIVWTGVYPEIYNDYGEKKIFSAARLLRNPRDYEE 195
           +++N + L  +   PWY+ +  A G IVW+G+Y + Y + G   + S+AR+LR+P  Y+ 
Sbjct: 154 EKVNFFSLDSLMGEPWYKEILAANGSIVWSGIYRQSYLEAGNVDVLSSARMLRDPEHYDR 213

Query: 196 IVGVLVMDVSETLVQEIVSELQFSEKYAPYLLDGRGKLIYGTTGPEGVESDAAAGSEQKM 255
           I GV+++DV E +V +++S L+FS     YL+D  G +I     P+          E + 
Sbjct: 214 ISGVMMIDVKEKMVSDLLSALEFSSGTQVYLVDSNGTVI---DHPDRARIGTQIAPEMR- 269

Query: 256 NQLPEDVLSAISHSEEGVVKRTIGRDXXXXXXXXXXXXXWKLVAQVSEAEISHRATALGQ 315
                D L+A S    G   R + +D             WKLVAQ S  ++S +A  L Q
Sbjct: 270 -----DRLNA-SKDSGGHAFR-LSKDSDEVMFTTVSPTNWKLVAQNSGGQLSPQAVKLTQ 322

Query: 316 FTSIATLAGITXXXXXXXXXXXXXXIQGVQRRVQMILRMIRKEGIGWLEERRSMPDGDFR 375
            +S+ +L                  ++G+ +RV+ ++ +IR+EG   LEE   + + DF 
Sbjct: 323 RSSLTSLLEYFALFTLLPFVLLAIIVRGMNQRVRKVITVIRREGTESLEELPVVANSDFL 382

Query: 376 LLERSVDHLIHKVNNLVEESYQAKIQEREAQLRTLQAQINPHFLYNALDMINWSAISHNA 435
            LERSVDHLI +V  LVEE Y A+I EREAQL+ LQAQINPHFLYN LDMINW AI   A
Sbjct: 383 ALERSVDHLILRVRTLVEEKYLAEIHEREAQLQALQAQINPHFLYNTLDMINWIAIGKGA 442

Query: 436 EDTSEMIEALAQYFRLSLNKGRDNVSIEDELELVRVFLEIQQNRFPSTFTFSIQAEPGLE 495
            D S+MI++LA+YFRLSLNKG+  VS+EDE+ L  V+L IQQ+RFP+TF   ++  P + 
Sbjct: 443 SDISQMIDSLAKYFRLSLNKGKSIVSVEDEVRLAEVYLGIQQSRFPNTFDVRVEVNPQIA 502

Query: 496 SYIIPKLTLQPLVENALLHGIRKTKSKQGTIEISVRLENGDVVLTVADDGIGMDPKQANR 555
              IPKL LQP+VENALLHGIRK K ++G I I V  EN D+++T++D+GIGM+ ++  +
Sbjct: 503 GCRIPKLILQPIVENALLHGIRKMKQRRGLISIIVTEENEDLLITISDNGIGMEEERVRQ 562

Query: 556 LL---LEPAAGQQADGMEGSFGLYNVQERIRYFAGNRYGLSIETEPGKGT 602
           LL   L P   +++D    S+GL+NV ERI+ ++G+ YGL I +  G GT
Sbjct: 563 LLKAALPPE--EKSDATGSSYGLFNVNERIKLYSGDHYGLEITSALGVGT 610


>B3KF79.1 B3KF79_9BACI Histidine kinase internal region
          Length = 629

 Score =  449 bits (1154), Expect = e-124,   Method: Compositional matrix adjust.
 Identities = 258/624 (41%), Positives = 365/624 (58%), Gaps = 38/624 (6%)

Query: 1   MKKAWAYLIGLSQGILSA---------KNWXXXXXXXXXXPVSIMLGTFYQRSNEVLEKE 51
           M++AW  + GL   +L           ++W          P  I L  +Y RS ++L  E
Sbjct: 1   MRRAWVAVTGLLSPLLQPAAIRRFSIPRSWLIAYLLLIVLPAGIFLYGYYARSADILRSE 60

Query: 52  VTRTMQLTLKQAGMNLTYKLNHIRDSSNSVFMNQILYDNL-LQKD--KITDQLGQIRELR 108
           V RTMQ  LKQAG NL+Y+L  I D S++ FMN  L+  L +  D   I  Q+  I +LR
Sbjct: 61  VIRTMQQALKQAGSNLSYRLERIEDISDAAFMNANLHSYLSINSDDQSIGTQIKVIEDLR 120

Query: 109 NLAETAQENEDIFRLRFFVEASRMYGGDRINLYPLADMDQYPWYEAVKEAGGGIVWTGVY 168
            L ET Q N D+F +R FV+ S++Y  +RIN + L  +   PW+ ++ +  GGIVWTGVY
Sbjct: 121 YLVETVQSNSDVFHVRVFVDKSKLYAEERINFFTLDSLMVRPWFHSIIDGNGGIVWTGVY 180

Query: 169 PEIYNDYGEKKIFSAARLLRNPRDYEEIVGVLVMDVSETLVQEIVSELQFSEKYAPYLLD 228
            E Y     + I SAAR+LR+P +Y+++ GVL++DV + +V  I+S+LQF+   A YL+ 
Sbjct: 181 EESYLGGSNETILSAARMLRDPDNYDKVSGVLMIDVRQDIVSNILSDLQFAPGTAVYLVA 240

Query: 229 GRGKLIYGTTGPEGVESDAAAGSEQKMNQLPEDVLSAISHSEEGVVKRTIGRDXXXXXXX 288
             G ++Y    P+    +A  G       +   +L A++   EG     +  +       
Sbjct: 241 QDGSIVYH---PD----EALIG-----KAVDPHLLDALNEGAEGTKSLLLNNEQSDVLYT 288

Query: 289 XXXXXXWKLVAQVSEAEIS---HRATALGQFTSIATLAGITXXXXXXXXXXXXXXIQGVQ 345
                 WKLVAQ +E+++S    R T   ++ S+     +               ++G+ 
Sbjct: 289 TLAPTGWKLVAQGTESQLSPATQRQTKQSEWRSLIEYVAL---FLILPFVLLAIIVRGMN 345

Query: 346 RRVQMILRMIRKEG------IGWLEERRSMPDGDFRLLERSVDHLIHKVNNLVEESYQAK 399
           RRV  ++ +IRKEG      I  L E  ++ +GDF +LERSVDHLI +V  LVEE+Y+A+
Sbjct: 346 RRVNHVITVIRKEGKEGKEAIDGLHELPAV-NGDFHMLERSVDHLILRVRTLVEENYRAE 404

Query: 400 IQEREAQLRTLQAQINPHFLYNALDMINWSAISHNAEDTSEMIEALAQYFRLSLNKGRDN 459
           I+EREAQL  LQAQINPHFLYN LD INW AI   A D S MI++LA+YFRLSLNKG   
Sbjct: 405 IREREAQLSALQAQINPHFLYNTLDTINWIAIGKGATDISMMIDSLAKYFRLSLNKGNTI 464

Query: 460 VSIEDELELVRVFLEIQQNRFPSTFTFSIQAEPGLESYIIPKLTLQPLVENALLHGIRKT 519
           VS+ DEL L  V+LEIQQ+RF  +F F + A   L++Y +PKL LQP+VENALLHGIRK 
Sbjct: 465 VSVTDELRLAEVYLEIQQSRFFGSFDFKVAAGDELKAYRMPKLILQPIVENALLHGIRKA 524

Query: 520 KSKQGTIEISVRLENGDVVLTVADDGIGMDPKQANRLLLEP-AAGQQADGMEGSFGLYNV 578
           K ++G I+I+V L+  D+V  ++D+GIGMD + +  LL E   +     G   S+GL+NV
Sbjct: 525 KDRKGLIDITVELDQSDLVFVISDNGIGMDEEMSRSLLTEERVSPSDHTGNGSSYGLFNV 584

Query: 579 QERIRYFAGNRYGLSIETEPGKGT 602
            ERI+  +G  YGLSI ++   GT
Sbjct: 585 NERIKLHSGEGYGLSISSKLSAGT 608


>B8I948.1 B8I948_CLOCE Histidine kinase
          Length = 600

 Score =  248 bits (632), Expect = 2e-63,   Method: Compositional matrix adjust.
 Identities = 170/576 (29%), Positives = 285/576 (49%), Gaps = 31/576 (5%)

Query: 32  PVSIMLGTFYQRSNEVLEKEVTRTMQLTLKQAGMNLTYKLNHIRDSSNSVFMNQILYDNL 91
           P++I++  +   S  ++E E++  MQL + Q   NL Y+   I +S+ S+      Y   
Sbjct: 37  PLTIIVYLYSIHSANIIENELSNNMQLAVSQIKNNLDYRFEQISESALSILSTAYPYIRS 96

Query: 92  LQKDKITDQLGQIRELRNLAETAQENEDIFRLRFFVEASRMYGGDRINLYPLADMDQYPW 151
                +  QL +  EL++L    +    I ++R +V + ++Y   +   Y L ++     
Sbjct: 97  -GSTSVETQLKEYDELKSLVSAYEGKHMISKVRLYVPSGKIYANQQETFYSLPELTD--- 152

Query: 152 YEAVKEAGGGIVWTGVY-PEIYNDYGEKKIFSAARLLRNPRDYEEIVGVLVMDVSETLVQ 210
            ++ +    G++W   Y   IY   G   I S    + +  +Y+EI  +L +D+ ET + 
Sbjct: 153 -QSRETYQRGVIWLKTYGSRIYEGRGLTNIISCRMTISSKTNYDEIASILQLDIEETKLS 211

Query: 211 EIVSE-LQFSEKYAPYLLDGRGKLIYGTTGPEGVESDAAAGSEQKMNQLPEDVLSAISHS 269
            I S  +   E+   YL+D  G +I   + P+     A  G     N L    LS +   
Sbjct: 212 RIFSAGISIDEEI--YLVDSDGVII---SHPDS----ALIGK----NGLSNTELSTVLLK 258

Query: 270 EEGVVKRTIGRDXXXXXXXXXXXXXWKLVAQVSEAEISHRATALGQFTSIATL--AGITX 327
           + G +   + ++             W LV ++    +    + +  F  +  L    +  
Sbjct: 259 KTGHLSGNMSQNADLVAFSKLSATDWYLVMRLPATAV--YGSDVFSFDVMRALLIIAVVV 316

Query: 328 XXXXXXXXXXXXXIQGVQRRVQMILRMIRKEGIGWLEERRSMPDG-DFRLLERSVDHLIH 386
                        I+   +R+   + ++  EGI  ++   S  +     LLE + + L+ 
Sbjct: 317 VFVISLILIYSSIIENTIKRINNAIMVLNNEGIDQVDSTLSKNNNKSLALLENNANQLVV 376

Query: 387 KVNNLVEESYQAKIQEREAQLRTLQAQINPHFLYNALDMINWSAISHNAEDTSEMIEALA 446
            +  L+EESY+AK++ R+ QL+ LQAQINPHFLYN LD I W  +  + +D+  MI A +
Sbjct: 377 TIKRLMEESYEAKLKARDYQLKALQAQINPHFLYNTLDSIKWMILEDHKKDSIWMINAFS 436

Query: 447 QYFRLSLNKGRDNVSIEDELELVRVFLEIQQNRFPSTFTFSIQAEPGLESYIIPKLTLQP 506
           +YFRLSL+KGRD V++ DELEL++ ++ I Q RF +  T  I  E  L+  +IPKL+LQP
Sbjct: 437 KYFRLSLSKGRDVVTLHDELELIQAYIGIMQKRFSNISTIDINIEDNLKECLIPKLSLQP 496

Query: 507 LVENALLHGIRKTKSKQGTIEISVRLENGDVVLTVADDGIGMDPKQANRLLLEPAAGQQA 566
           LVENAL HGI   ++  G + I+ + ENG + + + D+G GM  +Q  RLL E  +  + 
Sbjct: 497 LVENALNHGILHKQASDGQLVITAKEENGKLEIIIKDNGKGMSLEQLERLLNEENSNTKG 556

Query: 567 DGMEGSFGLYNVQERIRYFAGNRYGLSIETEPGKGT 602
                 +GL NV ER++ F G+  GL++ +E   GT
Sbjct: 557 ------YGLGNVDERLKLFGGDDCGLTVSSELNIGT 586


>B0K338.1 B0K338_THEPX Histidine kinase internal region
          Length = 567

 Score =  205 bits (522), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 162/561 (28%), Positives = 266/561 (47%), Gaps = 79/561 (14%)

Query: 48  LEKEVTRTMQLTLKQAGMNLTYKLNHIRDSSNSVFMNQILYDNLLQKDKITDQLGQIREL 107
           + +EV +T   TL QA  N++  L +++++   V MN+ L  NL                
Sbjct: 33  INEEVKKTTFQTLNQANKNISKMLENMKNAILYVSMNKELQYNLS--------------- 77

Query: 108 RNLAETA-QENEDIFRLRFFVEASRMYGG------DRINLYPLADMDQYP---------- 150
           RN  ET  Q N ++  +R     S +Y G        I ++ L   +QYP          
Sbjct: 78  RNGGETPFQINREVTAIR----NSILYPGIFNENYSSIEIFALHK-NQYPMRLEQNDVMS 132

Query: 151 --------WYEAVKEAGGGIVWTGVYPEIYNDYGEKKIFSAARLLRNPRDYEEIVGVLVM 202
                   WY+   +  G + W      I +D+G K++ S +RL+ + +++ + + V+ +
Sbjct: 133 SKVVENKEWYKKTIQLNGRLYWY-----INDDFG-KQMISVSRLVFDIKNFAKPIAVISV 186

Query: 203 DVSETLVQEIVSELQFSEKYAPYLLDGRGKLIYGTTGPEGVESDAAAGSEQKMNQLPEDV 262
           D+  + V  +VS++   +    YL+D +GKLIY               SE K        
Sbjct: 187 DMDMSKVASVVSDIHLGKTGKVYLVDDKGKLIY---------------SEDK--SFLYRY 229

Query: 263 LSAISHSEEGVVKRTIGRDXXXXXXXXXXXXXWKLVAQVSEAEISHRATALGQFTSIATL 322
            + + +S  G    TI  +             WKLV  VS AE++ +A  +  F  +  L
Sbjct: 230 TTKLYNSSSGSDFITINGNKIMVIYNTLPQNGWKLVGMVSMAELNEKAEMIRNFIYLTAL 289

Query: 323 AGITXXXXXXXXXXXXXXIQGVQRRVQMILRMIRKEGIGWLEERRSMPDGDFRLLERSVD 382
             +                   Q  +++   M + E   +        DG+  +L  S +
Sbjct: 290 LSLVIAALISLYFSYSIS----QPIIKLATEMKKVEKGNFNISVEENWDGEIGVLYSSFN 345

Query: 383 HLIHKVNNLVEESYQAKIQEREAQLRTLQAQINPHFLYNALDMINWSAISHNAEDTSEMI 442
           ++I ++N L+ E Y +KI+E++A+L+ LQAQINPHFLYN LD +NW A+ HN  + S+++
Sbjct: 346 YMIERINELIHEVYLSKIKEKDAELKALQAQINPHFLYNTLDTVNWLAVKHNVPEISKIV 405

Query: 443 EALAQYFRLSLNKGRDNVSIEDELELVRVFLEIQQNRFPSTFTFSIQAEPGLESYIIPKL 502
            +LA   R S+NKG D  ++E+EL+ V  ++ IQ+ RF   F  S   +  +  Y   KL
Sbjct: 406 NSLASILRYSINKGNDVTTVENELKHVESYITIQKIRFKDKFEVSFNIDKRVLHYKTIKL 465

Query: 503 TLQPLVENALLHGIRKTKSKQGTIEISVRLENGDVVLTVADDGIGMDPKQANRLLLEPAA 562
            LQPLVENA++HGI +T   +G I I+  L+   +V  V ++G  +D    N+LL  PA 
Sbjct: 466 ILQPLVENAIIHGI-ETYEGKGKILINGYLDGEKIVFEVINNGNPIDLDLVNKLLDSPAD 524

Query: 563 GQQADGMEGSFGLYNVQERIR 583
            +       S+G+ NV ERI+
Sbjct: 525 DKD------SYGIQNVNERIK 539


>A8RMQ3.1 A8RMQ3_9CLOT Putative uncharacterized protein
          Length = 620

 Score =  186 bits (473), Expect = 5e-45,   Method: Compositional matrix adjust.
 Identities = 159/585 (27%), Positives = 280/585 (47%), Gaps = 58/585 (9%)

Query: 40  FYQRSNEVLEKEVTRTMQLTLKQAGMNLTYKLNHIRDSSNSVFMNQILYDNLLQKDKITD 99
           +Y  ++ +LE+    T+Q+       N    +N +   +  V     + DN+  +  I  
Sbjct: 53  YYMTASRILEEAEATTVQMV-----GNACQDINELFLQTFQVC--SAMNDNISMQKLIRR 105

Query: 100 QLGQIRELRN--------LAETAQENEDIFRLRFFVEASRMYGGDRINLYPLADMDQYPW 151
           Q   I+E+ +        +      N DIF +    +    Y  +  + + ++D     W
Sbjct: 106 QFSSIKEMYSHDLEGSMEMMVLPSYNRDIFGVYVLGDNGGRYKSNS-SSFLVSDPRDTDW 164

Query: 152 YEAVKEAGGGIVWTGVYPEIYNDYGEKKIFSAARLLRNP---RDYEEIVGVLVMDVSETL 208
           Y  +  A G   W   +P   N Y     +++   +  P   +      GV++ D+    
Sbjct: 165 YRII-HATGQAQW---FPPHENSYVVSTPYTSYVSMGIPFIDKATGRTKGVVLADIDSDK 220

Query: 209 VQEIVSELQFSEKYAPYLLDGRGKLIYGTTGP------EGVESDAAAGSEQKMNQLPEDV 262
           + +I +    S     +L+D R +++  T G       +GVE  A    E+ ++++PE  
Sbjct: 221 LSDIAAR-AVSGAGDVFLMDERNRIMNLTAGEGPWKDRDGVEK-ARRMVEENLSEIPEYG 278

Query: 263 LSAISHSE-EGVVKRTIGRDXXXXXXXXXXXXXWKLVAQVSEAEISHRATALGQFTSIAT 321
           +S +   + + VV +T+ +              WK+V  + +A I+ R+    +   I  
Sbjct: 279 VSHVLKDKGQLVVYQTLNQ------------TDWKIVGVIPKASIT-RSVEYIKVLMIML 325

Query: 322 LAGITXXXXXXXXXXXXXXIQGVQRRVQMILRMIRKEGIGWLEERRSMPDGD-FRLLERS 380
           LA                    V R +  +++ + +   G LE       GD   +L  S
Sbjct: 326 LA----LAVVISMILSEIVADSVTRPLFTLVKAMEQVCAGNLETSVETERGDEIGVLYDS 381

Query: 381 VDHLIHKVNNLVEESYQAKIQEREAQLRTLQAQINPHFLYNALDMINWSAISHNAEDTSE 440
            +H+  ++ NL++  Y+ + + R  +L+ LQAQINPHFLYN LD I WS      E++ E
Sbjct: 382 FNHMTGEMRNLIDTIYREQEKLRREELKALQAQINPHFLYNTLDSIIWSLRMRQVEESIE 441

Query: 441 MIEALAQYFRLSLNKGRDNVSIEDELELVRVFLEIQQNRFPSTFTFSIQAEPGLESYIIP 500
           M+ AL  +F++SL+KGRD ++IE+E++ ++ +L IQ  R+   F + I  +P + S   P
Sbjct: 442 MLTALTDFFKISLSKGRDIITIEEEVKHIKSYLSIQHRRYQEKFDYDIHVDPSILSCRTP 501

Query: 501 KLTLQPLVENALLHGIRKTKSKQGTIEISVRLENGDVVLTVADDGIGMD---PKQANRLL 557
           KL LQP+VENA+ HGI+  + K G I I +  + GDV+L V D G+GMD    ++ NR L
Sbjct: 502 KLILQPVVENAIYHGIKPMEEK-GYIYIHIFPQEGDVILQVQDTGMGMDEDTCRRLNREL 560

Query: 558 LEPAAGQQADGMEGSFGLYNVQERIRYFAGNRYGLSIETEPGKGT 602
              ++ QQ  G    +G+ NV ++I+   G++YG++IE+  G+GT
Sbjct: 561 DTISSDQQGTG----YGVRNVNDKIKIVYGSKYGVTIESAMGEGT 601


  Database: pfamseq
    Posted date:  Aug 5, 2010  3:22 PM
  Number of letters in database: 3,060,696,203
  Number of sequences in database:  9,421,015
  
Lambda     K      H
   0.317    0.134    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 9421015
Number of Hits to DB: 3,126,006,496
Number of extensions: 123853315
Number of successful extensions: 351940
Number of sequences better than 1.0e-05: 2033
Number of HSP's gapped: 349014
Number of HSP's successfully gapped: 2036
Length of query: 614
Length of database: 3,060,696,203
Length adjustment: 142
Effective length of query: 472
Effective length of database: 1,722,912,073
Effective search space: 813214498456
Effective search space used: 813214498456
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 134 (56.2 bits)