BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0571.0020.p (548 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1D5Y1.1 B1D5Y1_9BACL Two component transcriptional regulator, A... 507 e-141 B3KF78.1 B3KF78_9BACI Response regulator receiver 497 e-138 B8I947.1 B8I947_CLOCE Two component transcriptional regulator, A... 300 3e-79 B3KJG1.1 B3KJG1_9BACI Response regulator receiver 243 3e-62 B1D5Z5.1 B1D5Z5_9BACL Two component transcriptional regulator, A... 236 5e-60 >B1D5Y1.1 B1D5Y1_9BACL Two component transcriptional regulator, AraC family Length = 545 Score = 507 bits (1305), Expect = e-141, Method: Compositional matrix adjust. Identities = 260/553 (47%), Positives = 368/553 (66%), Gaps = 17/553 (3%) Query: 1 MKTLVIVDDEPSVLNGLRSYVDWAGQGIELIGTADDGDAGLEMIKALKPDIVLTDVQMPA 60 M L+IVDDE +V GL+SY +W+ GIE++G ADDGD EMI PD+VLTDV+MP Sbjct: 1 MYKLLIVDDETTVRMGLQSYFNWSSFGIEIMGEADDGDVAFEMIGREAPDLVLTDVRMPN 60 Query: 61 MDGIRMAAEVRAVLPFTKIVFISGHNDAEYLRSALQIHAVDYLLKPIRRKELASVMGKVT 120 MDGI +A + P KI+F+SGH+DA+YL+SA+++ AVDY+ KP+ +EL+SV+ V Sbjct: 61 MDGITLARLINEHYPHVKIIFVSGHDDADYLKSAMKLSAVDYIFKPVNLEELSSVLRHVV 120 Query: 121 GALDAEARERSRVKEMQAKLAQSLPLLRERFLLSVISDRINPAHIREKLEFLDLTLLSAS 180 LD + E+ R +E+Q +L + +P+LRE+FLLS++ + IRE+++FL+L+L + Sbjct: 121 SDLDEQRAEQQRKEELQVRLKEGMPVLREKFLLSLMGSGVQRQDIRERVQFLELSLPEEA 180 Query: 181 DYXXXXXXXXXXPQVLDTRSEQDKQLLSYTVLNIIQELIDKQMRGITFEKQPGEYVGILL 240 Y P+V+ TRSE+D+QLL Y++ NI QELID M G FE Q GE+ GI L Sbjct: 181 SYWVIVISVDDLPEVMSTRSERDRQLLWYSINNICQELIDSHMGGYVFEYQTGEFAGI-L 239 Query: 241 TRQLE---DGDXXXXXXXXXXXXXLLLLAESIRDNLRQWLKLSVTIGVGEGVSSLPELPL 297 R E GD LL L IRDNL +WLK+SVTIG+ + V+ L L Sbjct: 240 RRGAESEVSGD---------AAEGLLELTSRIRDNLERWLKISVTIGISDRVTGLGNLGN 290 Query: 298 SYKQARGAADQKWYLGKNRILSMDKLESAEHLRY---RYEAEWSERVLTALRSGDRERTL 354 YKQAR A + KWYLGKNRI++MD LES+E RYE + E + +AL++ + E+ Sbjct: 291 CYKQAREAVNHKWYLGKNRIITMDSLESSEQASLSAGRYEFVYDEELTSALKAANPEKLR 350 Query: 355 SELEQIFARLEQNRGQGSRYAQNVSLHLILQSGQVMLELNGMSEEWEQKEMEAWKQVMRQ 414 L+ IFA L +NR G +Y +NV + + L +GQ++LELN SEE E E W+ ++ + Sbjct: 351 EVLDAIFADLNRNRPDGLKYGRNVCMQIFLAAGQLLLELNMQSEELESAEAAVWESLLDR 410 Query: 415 ETIHDLLQYTAAYLQEVCDYSRLKRSGKASEVIERVRLLIGQRYSE-NLSAADIAEGVYL 473 ET+ ++ AYL C+ KR+GK + ++ERVR +I + YS +L+ DI V+L Sbjct: 411 ETLGEMRLILEAYLLAACERIGEKRTGKVANLVERVRAIIDRDYSNGSLTVTDIGREVFL 470 Query: 474 SPTYVRLLFKQETGETLFEYLTKVRIEQAKNLLKDPQNKLYEVCYAVGYTDPSHFSKLFK 533 +PTYV LL+KQETG+T+ EY+T+VR+E+AK +L+DPQ K Y++CYA+GYTDPS+F+KLFK Sbjct: 471 TPTYVSLLYKQETGQTVGEYMTQVRMEKAKEMLRDPQYKFYDICYAIGYTDPSYFTKLFK 530 Query: 534 KITGCTPSAYREQ 546 K+TG TPS YRE+ Sbjct: 531 KMTGVTPSGYREK 543 >B3KF78.1 B3KF78_9BACI Response regulator receiver Length = 546 Score = 497 bits (1279), Expect = e-138, Method: Compositional matrix adjust. Identities = 258/549 (46%), Positives = 364/549 (66%), Gaps = 12/549 (2%) Query: 1 MKTLVIVDDEPSVLNGLRSYVDWAGQGIELIGTADDGDAGLEMIKALKPDIVLTDVQMPA 60 M L+IVDDEP+V GLR+Y DWA GIE+ G ADDGD LEMI +PD++LTDV+MP Sbjct: 1 MYRLLIVDDEPAVRAGLRAYFDWAAYGIEVAGEADDGDVALEMIARDQPDLILTDVRMPN 60 Query: 61 MDGIRMAAEVRAVLPFTKIVFISGHNDAEYLRSALQIHAVDYLLKPIRRKELASVMGKVT 120 MDGI M+ + + P KI+F+SGH+DA+YL+SA+++ AVDY+ KP+ +EL++V+ +V Sbjct: 61 MDGITMSQCISSEYPAMKIIFVSGHDDADYLKSAMKVSAVDYIFKPVNLQELSTVIKRVV 120 Query: 121 GALDAEARERSRVKEMQAKLAQSLPLLRERFLLSVISDRINPAHIREKLEFLDLTLLSAS 180 LDAE+ ER +E+ KL + +PLLRE+FLLS+I + + + E++ FL L L + Sbjct: 121 ADLDAESSERIYKQELLVKLKEGMPLLREKFLLSMIREGAPKSELAERVSFLGLDLPVNA 180 Query: 181 DYXXXXXXXXXXPQVLDTRSEQDKQLLSYTVLNIIQELIDKQMRGITFEKQPGEYVGILL 240 Y V+ +RSE+D+QLL Y+VLNI +EL+D +RG FE++ GE+VG+L Sbjct: 181 SYWVMVVCVDDLADVMASRSERDRQLLWYSVLNIYEELLDAHLRGYAFEQRTGEFVGVLK 240 Query: 241 TRQLEDGDXXXXXXXXXXXXXLLLLAESIRDNLRQWLKLSVTIGVGEGVSSLPELPLSYK 300 + GD A +R NL +WLK+ VTIG+ + L L +YK Sbjct: 241 VSE-PGGDSVSEAAEALFAL-----AGDLRSNLERWLKIGVTIGISDMAGGLSGLAPAYK 294 Query: 301 QARGAADQKWYLGKNRILSMDKLESAE----HLRYRYEAEWSERVLTALRSGDRERTLSE 356 QAR A D KWYLGKNRI++MD LESAE +R +Y+ E +E++++AL++ D ++ Sbjct: 295 QAREAVDYKWYLGKNRIITMDSLESAEPEEGAMR-KYDYELNEKLISALKADDEDKISEA 353 Query: 357 LEQIFARLEQNRGQGSRYAQNVSLHLILQSGQVMLELNGMSEEWEQKEMEAWKQVMRQET 416 +E IFA L R G +Y +N+ + L+L GQ+++EL E E E E + + +ET Sbjct: 354 VEMIFASLSYTRPDGLKYGRNLCMQLVLAIGQLLMELGAGDPELEVMEGELTEALYAKET 413 Query: 417 IHDLLQYTAAYLQEVCDYSRLKRSGKASEVIERVRLLIGQRYSE-NLSAADIAEGVYLSP 475 + D+ +YL V ++ R KR+G+ + VIERVR I Q Y+ L+ ADI + VYLS Sbjct: 414 LKDMRGLIESYLATVGEHIREKRTGRVANVIERVRGYIDQNYANGGLTVADIGKAVYLSS 473 Query: 476 TYVRLLFKQETGETLFEYLTKVRIEQAKNLLKDPQNKLYEVCYAVGYTDPSHFSKLFKKI 535 TYV LLFKQETG+T+ EYLTKVR+++AK LL+DPQ K Y++CYA+GYTDPS+FSKLFKK+ Sbjct: 474 TYVSLLFKQETGQTVGEYLTKVRVDKAKELLRDPQYKFYDICYAIGYTDPSYFSKLFKKV 533 Query: 536 TGCTPSAYR 544 TG TPSAYR Sbjct: 534 TGVTPSAYR 542 >B8I947.1 B8I947_CLOCE Two component transcriptional regulator, AraC family Length = 539 Score = 300 bits (768), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 181/546 (33%), Positives = 291/546 (53%), Gaps = 18/546 (3%) Query: 1 MKTLVIVDDEPSVLNGLRSYVDWAGQGIELIGTADDGDAGLEMIKALKPDIVLTDVQMPA 60 M +IVDDE V GL+ + DW+ IE++ DG + +K D+VLTDV MP Sbjct: 1 MYKAIIVDDEDLVRQGLKKHFDWSDHNIEIVADLSDGQKAFQYVKDNHVDLVLTDVLMPY 60 Query: 61 MDGIRMAAEVRAVLPFTKIVFISGHNDAEYLRSALQIHAVDYLLKPIRRKELASVMGKVT 120 MDGI +A +R + P KI+FISGH+D YL++AL++ AVDY+LK I EL + +V Sbjct: 61 MDGITLAKNLRELYPEIKIIFISGHDDVSYLKNALKVEAVDYILKSIDLDELKDTVSRVV 120 Query: 121 GALDAEARERSRVKEMQAKLAQSLPLLRERFLLSVISDRI-NPAHIREKLEFLDLTLLSA 179 ++ E + + + +M+ L QS PLL+ERF +++I D NP ++E++ FL++ L Sbjct: 121 NTMNTENQSKKTMADMENLLNQSFPLLQERFFITMIRDDFENPDIMKERIAFLNIPLNDE 180 Query: 180 SDYXXXXXXXXXXPQVLDTRSEQDKQLLSYTVLNIIQELIDKQMRGITFEKQPGEYVGIL 239 Y +E+++Q+LS + N E+ + I FE + GEYV IL Sbjct: 181 MYYCVLVVQIQRIYSKFHVLTERERQILSLQIQNECTEVGKQYSDTICFENKQGEYVMIL 240 Query: 240 LTRQLEDGDXXXXXXXXXXXXXLLLLAESIRDNLRQWLKLSVTIGVGEGVSSLPELPLSY 299 LED LL ++E++ L ++ L V+IG+ + L + SY Sbjct: 241 --SLLED----------EYEETLLEVSENLDKRLNGYMNLPVSIGISDRFKGLENIKASY 288 Query: 300 KQARGAADQKWYLGKNRILSMDKLESAEHLRYRYEAEWSERVLTALRSGDRERTLSELEQ 359 + A + +++ L +S+DK E E L+ Y+ + + L SG+ E+ L + Sbjct: 289 ENASNSISKRYLLDDELTISVDKYEMDESLK-EYKERAKKSLQECLSSGNTEQVSEVLRE 347 Query: 360 IFARLEQNRGQGSRYAQNVSLHLILQSGQVMLELN-GMSEEWEQKEMEAWKQVMRQETIH 418 +F + + QN+ + L+L +++ ++ ++ + M K + + Sbjct: 348 LFHIIREKFPDDEE--QNLMIFLLLLPTRIVTDIKINKKSDYSNQRMILEKFLCCADFEE 405 Query: 419 DLLQYTAAYLQEVCDYSRLKRSGKASEVIERVRLLIGQRYSENLSAADIAEGVYLSPTYV 478 L Y + S + ++ + +I +VR I +R+ E +S + +A VYL+PTY+ Sbjct: 406 QCLLIQKLYFEVATLMSSMSKTYSHT-IINQVRKTIEERFKEQISISTLARDVYLTPTYL 464 Query: 479 RLLFKQETGETLFEYLTKVRIEQAKNLLKDPQNKLYEVCYAVGYTDPSHFSKLFKKITGC 538 +LFKQ TG T+ +YLT R+E+AK LL DP KLY+VCY VGY PS+FS+LFKK TG Sbjct: 465 CVLFKQVTGTTINDYLTLTRLEKAKKLLSDPYIKLYDVCYEVGYLSPSYFSRLFKKYTGI 524 Query: 539 TPSAYR 544 +PS YR Sbjct: 525 SPSEYR 530 >B3KJG1.1 B3KJG1_9BACI Response regulator receiver Length = 539 Score = 243 bits (621), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 158/555 (28%), Positives = 278/555 (50%), Gaps = 31/555 (5%) Query: 1 MKTLVIVDDEPSVLNGLRSYVDWAGQGIELIGTADDGDAGLEMIKALKPDIVLTDVQMPA 60 M T++IVDDEP V G+R+ + W+ G E IG ++G LE + +PD+VLTD+ MP Sbjct: 1 MYTILIVDDEPIVREGIRNRIQWSEHGYECIGDCENGRDALEAVTRHQPDVVLTDINMPY 60 Query: 61 MDGIRMAAEVRAVLPFTKIVFISGHNDAEYLRSALQIHAVDYLLKPIRRKELASVMGKVT 120 MDG+ ++ + P TKI+ ++G +D EY + A+++ D++LKP+ EL ++ K+ Sbjct: 61 MDGLELSRHITERFPKTKIIILTGFDDFEYAQQAVKLQVTDFILKPVTAAELRDMLDKLK 120 Query: 121 GALDAEARERSRVKEMQAKLAQSLPLLRERFLLSVISDRINPAHIREKLEFLDLTLLSAS 180 +D E +K ++ +L +SL LLRERFL + S + + + +L++ D+ L Sbjct: 121 LEMDEERGHTEHLKRLKKQLNESLVLLRERFLERLASSPMKRSEMESRLDYFDIPLRGP- 179 Query: 181 DYXXXXXXXXXXPQVLDTRSEQDKQLLSYTVLNIIQELIDKQMRGITFEKQPGEYVGILL 240 ++ D +L ++ + NI+QE++ + F + + + IL Sbjct: 180 ---LYIAMAADMDELRSDEQHADNELHAFALYNIMQEILAGEPGAAVFRYKENKVMTILS 236 Query: 241 TRQLEDGDXXXXXXXXXXXXXLLLLAESIRDNLRQWLKLSVTIGVGEGVSSLPELPLSYK 300 +D LAE IR + +Q++K +VT+G+G L ++ S K Sbjct: 237 GSDEKDLHARAQE-----------LAEDIRGSTKQFMKFTVTVGIGTICRELQDIRYSCK 285 Query: 301 QARGAADQKWYLGKNRILSMDKLESAEHLRYRYEAEWSERVLTALRSGDRERTLSELEQI 360 + A + + +G+++++ + LE E +++A+R+G T SE++ Sbjct: 286 ASEAALEYRLLIGRDQVVHITDLEKRGSGPLLDGIETETALVSAIRAG----TGSEVKAC 341 Query: 361 FARLEQNRGQGSRYAQNV---SLHLILQSGQVMLELNGMSEEWEQKEMEAWKQVMRQETI 417 RL G S + L ++L Q ++E+ E KE + ++ Sbjct: 342 IRRLINEIGSASISIELCYVRVLRVMLAVLQTLMEIGSNGNELIGKEKRLLSDLYSFRSL 401 Query: 418 HDLLQYTAAYLQEVC-----DYSRLKRSGKASEVIERVRLLIGQRYSENLSAADIAEGVY 472 ++ + +L EVC D ++ ++ S+++E V + E LS + ++ Sbjct: 402 DEIER----WLNEVCEQALRDVAKTRKDIARSQMLEAVDFIQRHYEDEELSIKTVCSRIF 457 Query: 473 LSPTYVRLLFKQETGETLFEYLTKVRIEQAKNLLKDPQNKLYEVCYAVGYTDPSHFSKLF 532 +S +Y LFK TG+T EY+T+VR+E+AK LLK K YE+ GY DP +FS LF Sbjct: 458 MSTSYFSALFKSHTGKTFVEYVTEVRMEKAKELLKHSLLKTYEIAAKTGYQDPQYFSVLF 517 Query: 533 KKITGCTPSAYREQL 547 KK TG TP+ YR ++ Sbjct: 518 KKHTGDTPTEYRNKM 532 >B1D5Z5.1 B1D5Z5_9BACL Two component transcriptional regulator, AraC family Length = 535 Score = 236 bits (601), Expect = 5e-60, Method: Compositional matrix adjust. Identities = 160/556 (28%), Positives = 283/556 (50%), Gaps = 35/556 (6%) Query: 1 MKTLVIVDDEPSVLNGLRSYVDWAGQGIELIGTADDGDAGLEMIKALKPDIVLTDVQMPA 60 M TL+IVDDEP++ G+R+ +DW GIE++G A DG GLE LKP I +TD++MP Sbjct: 1 MITLLIVDDEPNIRKGIRTSIDWEDYGIEVVGEAADGVEGLEKALKLKPHITVTDIRMPL 60 Query: 61 MDGIRMAAEVRAVLPFTKIVFISGHNDAEYLRSALQIHAVDYLLKPIRRKELASVMGKVT 120 MDG+ ++ ++ LP T+IV +SG+ D + + AL I DYLLKP+ +EL +M K++ Sbjct: 61 MDGLELSRHLKNQLPDTRIVILSGYEDFSFAKEALAIGVQDYLLKPVGAEELVDLMLKLS 120 Query: 121 GALD-AEARERSRVKEMQAKLAQSLPLLRERFLLSVISDRIN---------PAHIREKLE 170 + AEA +R+R QSL ++ ++ SD IN + I +K E Sbjct: 121 EEIKLAEADKRNR---------QSLNMMINENYQTIKSDFINRILQGGVTDSSAIFDKAE 171 Query: 171 FLDLTLLSASDYXXXXXXXXXXPQVLDTRSEQDKQLLSYTVLNIIQELIDKQMRGITFEK 230 L + LS +Y + + E ++L+ ++V+NI +E++ + +G+ Sbjct: 172 LLKIR-LSGPEYSILAIDIDDFALMTEDLPENKRELIRFSVMNIAEEVLLSRTQGLVCYS 230 Query: 231 QPGEYVGILLTRQLEDGDXXXXXXXXXXXXXLLLLAESIRDNLRQWLKLSVTIGVGEGVS 290 Q +G++ L D + E I+ ++ +LKLS++IG+ + Sbjct: 231 QFDHLIGMMSGGGLR-ADFVDH------------VCEEIQQAVKTYLKLSISIGISRNCT 277 Query: 291 SLPELPLSYKQARGAADQKWYLGKNRILS-MDKLESAEHLRYRYEAEWSERVLTALRSGD 349 + L SY +A A K + GK ++ + + S E Y +E + ++ L++ + Sbjct: 278 DIAVLSTSYAEAFSALKAKIHKGKGSLIRYQESMMSTEMQNVLYPSEEEKVIIGCLKTLN 337 Query: 350 RERTLSELEQIFARLEQNRGQGSRYAQNVSLHLILQSGQVMLELNGMSEEWEQKEMEAWK 409 S ++QIF R + +++ L+L + + E++ ++ Sbjct: 338 SSELHSAIDQIFDRFAAGQTDAP-VIRSICGRLLLMAVSGVEEMSVDVGSIIGTNFNPYR 396 Query: 410 QVMRQETIHDLLQYTAAYLQEVCDYSRLKRSGKASEVIERVRLLIGQRYSENLSAADIAE 469 ++ R +T+ DL ++ L + + + ++ K VI+ + + Y+ +S AD+A Sbjct: 397 EMERFDTLGDLRKWMNDVLHRLSELVQENKNQKFKGVIKTALRYMEENYNRAVSLADVAA 456 Query: 470 GVYLSPTYVRLLFKQETGETLFEYLTKVRIEQAKNLLKDPQNKLYEVCYAVGYTDPSHFS 529 VY++P Y+ +FK+E G E+L + RIE+AK LL +P K Y V VGY+D +FS Sbjct: 457 IVYVTPNYLSRIFKEEIGVNFVEWLNRYRIEKAKLLLSEPGAKTYAVAEKVGYSDYKYFS 516 Query: 530 KLFKKITGCTPSAYRE 545 ++FK+ C+P Y+E Sbjct: 517 QMFKRFADCSPKEYKE 532 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.134 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,875,991,481 Number of extensions: 109303041 Number of successful extensions: 410063 Number of sequences better than 1.0e-05: 12642 Number of HSP's gapped: 423233 Number of HSP's successfully gapped: 13289 Length of query: 548 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 407 Effective length of database: 1,732,333,088 Effective search space: 705059566816 Effective search space used: 705059566816 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)