BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0571.0011.p (579 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KF55.1 B3KF55_9BACI Histidine kinase internal region 228 1e-57 B8I0N1.1 B8I0N1_CLOCE Signal transduction histidine kinase, LytS 219 6e-55 B1DAU7.1 B1DAU7_9BACL Histidine kinase internal region 210 3e-52 B3KF20.1 B3KF20_9BACI Histidine kinase internal region 207 3e-51 B3K5N1.1 B3K5N1_9BACI Histidine kinase internal region 175 9e-42 >B3KF55.1 B3KF55_9BACI Histidine kinase internal region Length = 562 Score = 228 bits (581), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 166/556 (29%), Positives = 274/556 (49%), Gaps = 23/556 (4%) Query: 35 GVMLFFRSQGYYADVIYNKQVERLGFVNRSIENEIEIVKRVQYNVMMNDSIESIRYFYES 94 G+ L+ S + I N ++ F S+E EIE +K +Q+ + ++ + + Y Sbjct: 16 GIYLYNWSLNTVKNEIINSSTAQVSFYLTSLEEEIERIKILQHESLTDEYLGKLAVRY-- 73 Query: 95 STFFERYEMMEAMRG---QMEALKNSSRLVADAKIYFKSVNKVIGSD-EINDLDPAVWKD 150 + + YE+ME+MR ++ + NSS ++ + + K I S ++ +D + Sbjct: 74 -SIMDEYEIMESMRKLHQRLVTIHNSSSYTSNVSAHILPIQKTISSTATVSPIDMDKFDQ 132 Query: 151 IGRDLFTDSSPVQNYHDRLIIKEALTESPGSGLPDCVII-VDLDKMAIEEQLKYAQLTDQ 209 I + + Y + L I TE+ +GLP +I ++LD A +E L D Sbjct: 133 IRVPAGETGAQLVQYKNNLYITTLHTEN--AGLPQKYMIEIELDTTAFQEALGQFHTYDN 190 Query: 210 DIIALADRHHHIIVSSTV-DGYSLLKDTPELQKQIK--------LNGQKYEVIQSESSFL 260 L D H I++S D L+D ++K +NGQK V+ +S +L Sbjct: 191 SGSFLIDLTHDIVISGKGNDANVRLQDLAGNYHELKSGNVTYSNINGQKMYVVSVKSDYL 250 Query: 261 ETRLFWLYVDNTNQVAVGXXXXXXXXXXXXXXXXXXXXXXDSYRRVYNPLKILLEDAFQQ 320 L V + +Y ++ P++ L+ +F+ Sbjct: 251 NMLLLRYIPQELIFVPLRDFYIWLWVFTGAGAMIMLFYSIYTYNLIHKPMRKLV-GSFRH 309 Query: 321 VRAGNFKYRITKYEKSHLAPLYSSFNEMVSRIDTLIEKDLKQQLLISHAQLKHLQAQINP 380 V +GNF I K+ LY FN MV + LIE+ KQ++L A+LK LQ+QI+P Sbjct: 310 VESGNFNVSIHVNSKNEFGYLYQGFNSMVQNVSALIEQVYKQKILNQRAELKQLQSQISP 369 Query: 381 HFMYNSYYLLYRMIKMRDYENSVLLCEHLGKFYEYITRDGEDEKMLREEVEHARVYAAIQ 440 HF+YNS +L+ M K+ D +N + + LG ++++ITR+ D LREEVEHAR Y+ IQ Sbjct: 370 HFLYNSLFLINTMAKLGD-DNLIPFTKLLGDYFQFITRNASDFLPLREEVEHARTYSEIQ 428 Query: 441 SYRFGHRVRVEFGDLPENWAYELIPRLIIQPLLENAFHYGFEKVSSSGGNILRISFHQVD 500 RF R+ ++F DLP+ +PRLI+QP+LENAF Y E+ G ++ + F Q D Sbjct: 429 FMRFPSRLTIQFEDLPDEVKEIQVPRLILQPILENAFKYAVEQTKVKG--LITMRFQQED 486 Query: 501 KGLIICVENSGDDDEHTIQEISNLILRGNRDGEVTALSNIHKRLQIFFGPESGLAIVKSD 560 + L I VE++G D + +L + E + L NIH+RL++ +G E GL + +S Sbjct: 487 RALRIIVEDNGTDLSESKLSALQKLLNDTSNIETSGLINIHRRLRLIYGDEHGLFLERSA 546 Query: 561 LGGFRVEIHIPGQRTV 576 +GG +V + + + +V Sbjct: 547 MGGLKVTLQLDPKASV 562 >B8I0N1.1 B8I0N1_CLOCE Signal transduction histidine kinase, LytS Length = 574 Score = 219 bits (558), Expect = 6e-55, Method: Compositional matrix adjust. Identities = 155/584 (26%), Positives = 289/584 (49%), Gaps = 21/584 (3%) Query: 1 MIKAKPNNSNLVFRMIYKRFXXXXXXXXXXXXXXGVMLFFRSQGYYADVIYNKQVERLGF 60 M+K K NS I+ R G+ ++ S I V + F Sbjct: 1 MVKLKMRNS------IFSRLVITFMIIIIPLYSLGIYIYGSSLRTVKSEISKSTVAQASF 54 Query: 61 VNRSIENEIEIVKRVQYNVMMNDSIESIRYFYESSTFFERYEMMEAMRGQMEALKNSSRL 120 S+E EIE +K +QY+ + ++ + + +E + +E + + ++ ++ A+K+SS Sbjct: 55 YLESLEKEIERIKILQYDCLNDEQLNKLAIRWEIMSEYEISQTLLQLKQRLVAIKSSSIY 114 Query: 121 VADAKIYFKSVNKVIGSDE-INDLDPAVWKDIGRDLFTDSSPVQNYHDRLIIKEALTESP 179 V D ++ ++K + S+ ++D+ + I + + NY+ +L + + Sbjct: 115 VNDVNVHILPISKTVSSNSGVDDIHINEYNGIYVPAGLKGAQIINYNGQLYL-STFKKYS 173 Query: 180 GSGLPDCVIIVDLDKMAIEEQLKYAQLTDQDIIALADRHHHIIVSSTVDGYSLLKDTPEL 239 G+ P I ++L++ A+++ L+ L + I S D L++ Sbjct: 174 GATKPLFTINIELNQNALKQALEQFNTYAGSGSILITPTNIIANKSQEDNSQLIQSILLS 233 Query: 240 QKQ--------IKLNGQKYEVIQSESSFLETRLFWLYVDNTNQVAVGXXXXXXXXXXXXX 291 K+ K+ ++Y V+ S SS+L L + + Sbjct: 234 MKERDRDGTVFTKIGNKQYYVVHSNSSYLNMLLLRYFPQEFILKPLENFKTWAWVFSIAA 293 Query: 292 XXXXXXXXXDSYRRVYNPLKILLEDAFQQVRAGNFKYRITKYEKSHLAPLYSSFNEMVSR 351 +Y+ ++ PL L++ +F+++ G+ K I+ + LY FN+MV Sbjct: 294 ILIIIIYSFSTYKFMHQPLNELVK-SFRKIENGDLKVFISHDSNNEFGYLYKCFNDMVKN 352 Query: 352 IDTLIEKDLKQQLLISHAQLKHLQAQINPHFMYNSYYLLYRMIKMRDYENSVLLCEHLGK 411 ++ LI++ Q++L+ A+LKHLQ+QINPHF+YNS++++ M ++ D EN V +HLG+ Sbjct: 353 LNMLIDQVYNQKILMQKAELKHLQSQINPHFLYNSFFMINTMARIGD-ENLVPFTKHLGE 411 Query: 412 FYEYITRDGEDEKMLREEVEHARVYAAIQSYRFGHRVRVEFGDLPENWAYELIPRLIIQP 471 ++ ++TR+ D L EE+ HA+VY IQ RF R+++ FG+ P + +PRLI+QP Sbjct: 412 YFRFVTRNSMDNLSLEEEINHAKVYTEIQLMRFSKRIQIHFGECPNMYKDLKVPRLILQP 471 Query: 472 LLENAFHYGFEKVSSSGGNILRISFHQVDKGLIICVENSG-DDDEHTIQEISNLILRGNR 530 ++ENAF +G EK G +L ++F ++ L I VE++G D + ++++ N + Sbjct: 472 IIENAFEHGLEK--KKNGGLLLVNFEGNERELRIVVEDNGFDITDSELEKLQNSLEDNGL 529 Query: 531 DGEVTALSNIHKRLQIFFGPESGLAIVKSDLGGFRVEIHIPGQR 574 + E T NIH+R+++ FG ESGL I +S +GG + + I Q+ Sbjct: 530 EIETTGTLNIHRRIRLVFGEESGLIISRSVIGGLKAVLKIVLQK 573 >B1DAU7.1 B1DAU7_9BACL Histidine kinase internal region Length = 589 Score = 210 bits (534), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 151/553 (27%), Positives = 274/553 (49%), Gaps = 28/553 (5%) Query: 35 GVMLFFRSQGYYADVIYNKQVERLGFVNRSIENEIEIVKRVQYNVMMNDSIESIRYFYES 94 GV L+ S ++ I +L + ++++IE ++ QY+++ ++ + + + Sbjct: 39 GVYLYNWSYANASNEISKNTTAQLSYYLEDLDHQIEWLEIQQYDILQDNDLNKLAVTWNL 98 Query: 95 STFFERYEMMEAMRGQMEALKNSSRLVADAKIYFKSVNKVIGSDEINDLDPAVWKDIGRD 154 ++ ++ + + ++KNSS + D ++ +++ K I S+ N +D D R Sbjct: 99 MDNADKKASIDYLLHRFTSIKNSSVYIKDIYVHVRTIQKTISSN--NGVD-----DFNRL 151 Query: 155 LFTD-SSPVQNYHDRLIIKE------ALTESPGSGLPDCVIIVDLDKMAIEEQLKYAQLT 207 F + V RLI+ + A G P ++ ++L+ + E L+ + Sbjct: 152 SFNYFHNEVDKKEARLILYDHSLHLSAAKYGGKEGDPVFIVQIELNMDKLRESLQQISVY 211 Query: 208 DQDIIALADRHHHIIVSSTVDGYSLLKDT-------PELQKQIKLNGQKYEVIQSESSFL 260 + L ++S D +L+ + E ++ +KY + ++ S L Sbjct: 212 PESGSFLISNKMGYTLASNGDTSDVLQSSVIGALHAEENTLITQIGDKKYHLDKAYSEPL 271 Query: 261 ETRLFWLYVDNTNQVAVGXXXXXXXXXXXXXXXXXXXXXXDSYRRVYNPLKILLEDAFQQ 320 + ++ + + +Y+ V+ PL +LL +F++ Sbjct: 272 GLSVITYLPESVVKKPLNGFNNWAWIFALTSCCAIVIYALSTYKFVHKPL-LLLVQSFRK 330 Query: 321 VRAGNFKYRITKYEKSHLAPLYSSFNEMVSRIDTLIEKDLKQQLLISHAQLKHLQAQINP 380 + G I +K LY+ FN+M+ ++ TLI++D KQ +++ A+LK LQ+QI P Sbjct: 331 MEGGALNIHIDHEKKDEFGYLYNRFNQMIKKLQTLIDQDFKQTMMMQKAELKQLQSQIKP 390 Query: 381 HFMYNSYYLLYRMIKMRDYENSVLLCEHLGKFYEYITRDGEDEKMLREEVEHARVYAAIQ 440 HF+YNS+++L + K D E L LG++Y +ITR+GED +L EE H+ +Y IQ Sbjct: 391 HFLYNSFFILNSLAKTGDLERVQLFTNMLGEYYRFITRNGEDNVLLAEETRHSGMYTEIQ 450 Query: 441 SYRFGHRVRVEFGDLPENWAYELIPRLIIQPLLENAFHYGFEKVSSSGGNILRISFHQVD 500 RF R++VEF +LP N +PRLIIQP++ENA+ + EK+++ G +LR+SF + Sbjct: 451 KLRFSRRIKVEFDELPGNMERIRVPRLIIQPIIENAYEHSLEKMTNEG--LLRVSFFMNE 508 Query: 501 KGLIICVENSGD---DDEHTIQEISNLILRGNRDGEVTALSNIHKRLQIFFGPESGLAIV 557 + I VEN+GD DE I + + GE+T + NIH+R+ + +G SGL + Sbjct: 509 EEARIIVENNGDYPITDEQ-IDALQERLDSKGESGEMTGMINIHRRIVLTYGEGSGLFLS 567 Query: 558 KSDLGGFRVEIHI 570 KS+L G +VEI I Sbjct: 568 KSELNGLKVEIRI 580 >B3KF20.1 B3KF20_9BACI Histidine kinase internal region Length = 583 Score = 207 bits (527), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 143/546 (26%), Positives = 266/546 (48%), Gaps = 13/546 (2%) Query: 35 GVMLFFRSQGYYADVIYNKQVERLGFVNRSIENEIEIVKRVQYNVMMNDSIESIRYFYES 94 GV L+ S Y + I +L + EIE ++ QY+++ + + + +E Sbjct: 32 GVYLYNWSYQYASQEISKNSQAQLSAYLDGLNREIEWLEIQQYDILQDGELNKMVLTWEM 91 Query: 95 STFFERYEMMEAMRGQMEALKNSSRLVADAKIYFKSVNKVIGS-DEINDLDPAVWKDIGR 153 + +R + + ++ ++KNSS + D ++ + ++K I + +N D + ++ Sbjct: 92 MSTVDRKASLHYLLPRLVSIKNSSVYIKDVFVHIRGMDKTISAMTGMNPFDSIRYNNVQV 151 Query: 154 DLFTDSSPVQNYHDRLIIKEALTESPGSGLPDCVIIVDLDKMAIEEQLKYAQLTDQDIIA 213 ++ + D L + A + P ++ ++LD + E L + + Sbjct: 152 GKAHGNARLLQIDDTLHLVAAKYGARKGEEPFLIVQIELDPSKLRESLMQISVYPESGAF 211 Query: 214 LADRHHHIIVSSTVDGYSLL----KDTPELQKQIKLNGQ-KYEVIQSESSFLETRLFWLY 268 + ++S + L+ + P +Q+ + G +Y + ++ S L+ +F Sbjct: 212 IVSEPSGFALASHEEADRLMGGAMQAIPNANRQLIMIGTGRYLIDKAYSDKLKLSVFTYL 271 Query: 269 VDNTNQVAVGXXXXXXXXXXXXXXXXXXXXXXDSYRRVYNPLKILLEDAFQQVRAGNFKY 328 + + +Y+ V+ PL +LL +F+++ G F Sbjct: 272 PTEVVKRPLSKFYVWAWLFAGTTLLAIAIYAVSTYKLVHKPL-LLLVQSFRKMEDGMFNI 330 Query: 329 RITKYEKSHLAPLYSSFNEMVSRIDTLIEKDLKQQLLISHAQLKHLQAQINPHFMYNSYY 388 RI ++ LY FN M+ ++ LI++D + +L++ A+LK LQ+QINPHF+YNS++ Sbjct: 331 RIRHGQRDEFGYLYDRFNHMLIKLQHLIDQDFRHKLMMQRAELKQLQSQINPHFLYNSFF 390 Query: 389 LLYRMIKMRDYENSVLLCEHLGKFYEYITRDGEDEKMLREEVEHARVYAAIQSYRFGHRV 448 +L + K D L LG+++ +ITR+ D L EE H+R+Y IQ RF R+ Sbjct: 391 ILSSLAKTGDVAQIELFTNMLGEYFRFITRNDADNVPLLEETRHSRIYTEIQKLRFSRRI 450 Query: 449 RVEFGDLPENWAYELIPRLIIQPLLENAFHYGFEKVSSSGGNILRISFH-QVDKGLIICV 507 RV+FG+LP+ +PRLIIQP++ENA+ + EK+ G +L ++FH D+ I+ Sbjct: 451 RVQFGELPKEMETIKVPRLIIQPIIENAYEHSLEKMQDEG--LLHVAFHLDKDEASIVIE 508 Query: 508 ENSGDDDEHTIQEISNLILRGNRDG---EVTALSNIHKRLQIFFGPESGLAIVKSDLGGF 564 EN ++ I+E++ + R + EVT L NIH+R+ + +G SGL + +S L G Sbjct: 509 ENGNGLTDNEIEELNRRLERTSESAESPEVTGLINIHRRIALTYGESSGLVLSRSPLNGL 568 Query: 565 RVEIHI 570 RV+I I Sbjct: 569 RVQIRI 574 >B3K5N1.1 B3K5N1_9BACI Histidine kinase internal region Length = 582 Score = 175 bits (444), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 147/557 (26%), Positives = 262/557 (47%), Gaps = 39/557 (7%) Query: 36 VMLFFRSQGYYADVIYNKQVERLGFVNRSIENEIEIVKRVQYNVMMNDSIESIRYFYESS 95 + L ++ + I N F + ++ E+ ++ +Q ++ + ++ + + Sbjct: 34 IWLNYKGMSVTKESILNSAAAGASFYSTQLDKEMYFIRNLQLQLLNDKDLQKLSFRGSML 93 Query: 96 TFFERYEMMEAMRGQMEALKNSSRLVADAKIYFKSVNKVIGSDEINDLDPAVWKDIGR-D 154 +E E+++ +R ++ L SS V A +Y K V K I + P K++ R Sbjct: 94 EDYEEVELIDQVRDRLATLMVSSEYVVSAGVYVKDVGKTISTTTGVTNTPN--KEMERIS 151 Query: 155 LFTDSSPVQNYH---DRLIIKEALTESPGSGLPDCVIIVDLDKM--AIEEQLKYAQLTDQ 209 P +++ DR+ L E+ +G I + K+ A+ E A+L + Sbjct: 152 SMMAVMPKPSFYRSGDRIF----LIETENNGAVWSYIEISRPKLLGALSE---IAKLYPE 204 Query: 210 DIIALADRHHHIIVSS------TVDGYSLLKDTPELQKQI----KLNGQKYEVIQSESSF 259 + L R I+++ + + + + D P+ + +L G Y +IQ+E Sbjct: 205 SEVLLGSREGSTILTTAPAADESTEILNHVLDKPDTDRNAPETGELGGVDYFIIQNEVGS 264 Query: 260 LETRLFWLYVDNTNQVA--VGXXXXXXXXXXXXXXXXXXXXXXDSYRRVYNPLKILLEDA 317 L+ L +YV N N++ + ++ PL L++ A Sbjct: 265 LDLSLV-MYV-NQNEITRPISQFITWFYTLFILAVIVMVLYSFSVNLMIHRPLSKLVK-A 321 Query: 318 FQQVRAGNFKYRITKYEKSHLAPLYSSFNEMVSRIDTLIEKDLKQQLLISHAQLKHLQAQ 377 F + N I K +++ FN M ++ IE++ +Q++ + H+QLK LQ+Q Sbjct: 322 FHMIETDNLNILIESRTKDEFHYVFNGFNRMALKLKQSIEENYEQKIALQHSQLKQLQSQ 381 Query: 378 INPHFMYNSYYLLYRMIKMRDYENSVLLCEHLGKFYEYITRDGEDEKMLREEVEHARVYA 437 INPHF+YNS++ +Y M K+ D +++ L + LG +Y+YITR G DE E HA Y Sbjct: 382 INPHFLYNSFFNVYMMCKVGDSDSAAELSQKLGSYYQYITRSGSDEVPFYTEYRHALDYC 441 Query: 438 AIQSYRFGHRVRV---EFGDLPENWAYELIPRLIIQPLLENAFHYGFEKVSSSGGNILRI 494 IQ RF +R+ EF D+P+ +PRLI+QP++ENAF + FE G +L I Sbjct: 442 DIQGIRFSNRISYEHREFADIPQGIT---VPRLIVQPIVENAFEHAFEDGMEEG--MLYI 496 Query: 495 SFHQVDKGLIICVENSGD-DDEHTIQEISNLILRGNRDGEVTALSNIHKRLQIFFGPESG 553 S + L I VE++G+ +Q + + ++ E T L N++ RLQ+ +GP SG Sbjct: 497 SADYREGRLRITVEDNGNLLTNEMLQRLRGKLAMDSKHVEQTGLVNVNNRLQLKYGPGSG 556 Query: 554 LAIVKSDLGGFRVEIHI 570 L + +S GG +V++ I Sbjct: 557 LTVSRSVHGGLKVDLII 573 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.138 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,118,196,427 Number of extensions: 126596717 Number of successful extensions: 329148 Number of sequences better than 1.0e-05: 1745 Number of HSP's gapped: 326579 Number of HSP's successfully gapped: 1747 Length of query: 579 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 438 Effective length of database: 1,732,333,088 Effective search space: 758761892544 Effective search space used: 758761892544 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)