BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0568.0005.p (367 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K9F2.1 B3K9F2_9BACI Sensor protein EC=2.7.13.3 318 5e-85 B1D5H1.1 B1D5H1_9BACL Sensor protein EC=2.7.13.3 286 2e-75 Q67LF6.1 Q67LF6_SYMTH Sensor protein EC=2.7.13.3 265 6e-69 A7GPQ4.1 A7GPQ4_BACCN Sensor protein EC=2.7.13.3 239 4e-61 C2KV58.1 C2KV58_9FIRM Sensor histidine kinase 236 3e-60 >B3K9F2.1 B3K9F2_9BACI Sensor protein EC=2.7.13.3 Length = 405 Score = 318 bits (815), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 187/405 (46%), Positives = 245/405 (60%), Gaps = 57/405 (14%) Query: 8 TIRWKFIWAFILSVVSGAILLIGGYRLVNSLVYLNPS--PPSAAYSQLLRWVINHIGSVP 65 +IR K + + S+ A LLI Y L ++LV P+ PP L W++N++GS P Sbjct: 8 SIRLKMLLMLLASIGIAAALLIILYAL-STLVLSIPAINPP-------LAWIVNNLGSKP 59 Query: 66 VMTAAGILSFLFFFFIYTR----------------------------------------- 84 VM GI+ FL +++ TR Sbjct: 60 VMLFTGIILFLASYYMSTRWFALDLRKVETGLQDITAGRFDSRIELDTRDEVGAVAAGIN 119 Query: 85 ----KIVLYLEEITRGIQQITKLGESHRIEVRTADELGLLAENINIMSERLQHSLLEERK 140 ++ +YLEEIT G+++I K I VR+ +LG +AE+IN MS +L S+LEER Sbjct: 120 RMTEQLNVYLEEITHGLREIAKGNFDTEIPVRSGSQLGEVAESINQMSRQLHQSILEERH 179 Query: 141 TVAAKNELITGVSHDLRTPLTSVLGYLEYIEQDRCREETELRYYVNIAYQKALVLQKLID 200 KN+LITGVSHDLRTPLTS+LG+LE IE+DR ++E ELRYYVNIAY+KA L+KLID Sbjct: 180 AEKTKNDLITGVSHDLRTPLTSILGFLEVIEEDRYQDEVELRYYVNIAYEKAQNLKKLID 239 Query: 201 DLFEYTRVSSGGLPLVPERLDLKAFMRQLAEEAVPELARAGMTYELVDETDSLWIQAAPY 260 DLFEYTR+++ GLPL +D+ FMRQL EE VP L +AGM +L E D L I+A Sbjct: 240 DLFEYTRINN-GLPLDIREIDMAQFMRQLIEEFVPSLEKAGMECKLAAE-DGLVIRADGA 297 Query: 261 ELLRAYENLITNAIRYGREGKRLEIGLSREGDEAVVRISNFGERIAESDLPHIFERFYRA 320 +L+RAYENLI+NAIRYG G R++I + G + + +N+G+ I E DLP IF+RFYR Sbjct: 298 QLVRAYENLISNAIRYGESGHRIDIAVRSVGGQVSISFTNYGDPIPERDLPFIFDRFYRV 357 Query: 321 ERSRSQYTGGSGLGLAIAKGIVERHKGVISAASDMYRTDFITRYP 365 E SRS+ TGG+GLGLAI K IVE G I SD RT F TR+P Sbjct: 358 EASRSKQTGGTGLGLAITKSIVEVQGGEIRVRSDRQRTTFETRFP 402 >B1D5H1.1 B1D5H1_9BACL Sensor protein EC=2.7.13.3 Length = 376 Score = 286 bits (733), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 170/361 (47%), Positives = 227/361 (62%), Gaps = 7/361 (1%) Query: 8 TIRWKFIWAFILSVVSGAILLIGGYRLVNSLVYLNPSPPSAAYSQLLRWVINHIGSVPVM 67 ++R+K ++ F LS + GA G LV Y S S LLR V + G + Sbjct: 8 SLRFKMLYLFGLSAL-GAFFTTGLLYLVAVSAY---STDIFNLSPLLREVFDKFGLLTTY 63 Query: 68 TAAGILSFLFFFFIYTRKIVLYLEEITRGIQQITKLGESHRIEVRTADELGLLAENINIM 127 + FL +FF +R + YL I++GI++I R+ VR DELG LAENIN M Sbjct: 64 ITVSLFFFLVYFFALSRSTIRYLMRISQGIERIAGGDFESRLPVRGGDELGALAENINKM 123 Query: 128 SERLQHSLLEERKTVAAKNELITGVSHDLRTPLTSVLGYLEYIEQDRCREETELRYYVNI 187 + +L+ S+ EER+T K EL+T VSHDLRTPLTS++GYL IE+DR R+E ELR+YV I Sbjct: 124 TAQLKLSIEEERRTERTKAELVTNVSHDLRTPLTSIVGYLGLIEEDRYRDEVELRHYVQI 183 Query: 188 AYQKALVLQKLIDDLFEYTRVSSG-GLPLVPERLDLKAFMRQLAEEAVPELARAGMTYEL 246 AYQK+ L+ +IDDLFEYTR S G GL L P ++L + QLA + + +AGM L Sbjct: 184 AYQKSTRLKTMIDDLFEYTRTSGGIGLRLSP--INLVEMIGQLAAQFRLQFEQAGMKCRL 241 Query: 247 VDETDSLWIQAAPYELLRAYENLITNAIRYGREGKRLEIGLSREGDEAVVRISNFGERIA 306 S+ I A +L+R +ENLI NAI+YG+EG++++I + E AVV I+N+GE + Sbjct: 242 ALPDHSILIDADGDKLVRVFENLIVNAIQYGKEGRQIDIAVWSERGLAVVEIANYGEPLP 301 Query: 307 ESDLPHIFERFYRAERSRSQYTGGSGLGLAIAKGIVERHKGVISAASDMYRTDFITRYPL 366 S +P +FERFYR E+SRS+ TGGSGLGLAIAK IVE H G+ISAAS +T F PL Sbjct: 302 ASVIPLLFERFYRGEQSRSRNTGGSGLGLAIAKNIVELHHGMISAASAEGKTSFKVELPL 361 Query: 367 A 367 Sbjct: 362 G 362 >Q67LF6.1 Q67LF6_SYMTH Sensor protein EC=2.7.13.3 Length = 383 Score = 265 bits (677), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 154/364 (42%), Positives = 223/364 (61%), Gaps = 15/364 (4%) Query: 8 TIRWKFIWAFI----LSVVSGAILLIGGYRLVNSLVYLNPSPPSAAYSQLLRWVINHIGS 63 ++RW+ I F+ L+ VS A++L L S+ PP ++ LL ++ + +G Sbjct: 8 SLRWRMILTFMASGFLAAVSTALMLAVAANLAGSI------PP---FNWLLNFLADTVGV 58 Query: 64 VPVMTAAGILSFLFFFFIYTRKIVLYLEEITRGIQQITKLGESHRIEVRTADELGLLAEN 123 P++ A ++ ++ + ++ ++ YLE ++R + ++ + + R DELGLL EN Sbjct: 59 WPIVFAVAVVLSFTWYILLSQPMIRYLEALSRAMDEVARGNYDVTVPPRGRDELGLLGEN 118 Query: 124 INIMSERLQHSLLEERKTVAAKNELITGVSHDLRTPLTSVLGYLEYIEQDRCREETELRY 183 + MS +++ SL ER+ A+ ELIT VSHDLRTPLTSVLGYL+ I++DR R+E ELRY Sbjct: 119 LVSMSRQIKASLQRERQANQARYELITAVSHDLRTPLTSVLGYLQLIDEDRYRDEVELRY 178 Query: 184 YVNIAYQKALVLQKLIDDLFEYTRVSSGGLPLVPERLDLKAFMRQLAEEAVPELARAGMT 243 YV++AY+KA L++LID LFE+TR S GG+ L P ++ + Q+AE VP L AGM Sbjct: 179 YVDMAYEKAKQLKRLIDQLFEFTRTSHGGIVLRPVPINPAELLEQVAEAFVPALQEAGME 238 Query: 244 YELVDETDSLWIQAAPYELLRAYENLITNAIRYGREGKRLEIGLS-REGDEAV-VRISNF 301 Y L + + A P L+R ENLI+NAIRYGREGK +E+ L R + AV +R++N Sbjct: 239 YRLRLPDERATVLADPDLLVRVLENLISNAIRYGREGKVVELELEVRRVERAVLLRVANR 298 Query: 302 GERIAESDLPHIFERFYRAERSRSQYTGGSGLGLAIAKGIVERHKGVISAASDMYRTDFI 361 G I L IF+ FYR E SRS TGG+GLGLAI + IV H G + A ++ RT F Sbjct: 299 GNPIPSHQLDRIFDSFYRGEVSRSGRTGGAGLGLAIVRNIVTLHGGTVRAINETDRTVFE 358 Query: 362 TRYP 365 R P Sbjct: 359 VRLP 362 >A7GPQ4.1 A7GPQ4_BACCN Sensor protein EC=2.7.13.3 Length = 384 Score = 239 bits (609), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 143/371 (38%), Positives = 209/371 (56%), Gaps = 22/371 (5%) Query: 10 RWKFIWAFILSVVSGAILLIGGYRLVNSLVYLNPSPPSAAYSQLLRWVINHIG------- 62 +WK + +L+++ I I YRLV S++ S ++L + ++ +G Sbjct: 14 KWKIVLWLVLAILLTPITEIIIYRLVTSVI-----DSSLTLTELGKEIVRIVGYEKYRGL 68 Query: 63 --SVPVMTAA-----GILSFLFFFFIYTRKIVLYLEEITRGIQQITKLGE---SHRIEVR 112 S+ M + I SF + F K + Y I R I++I + +H++ + Sbjct: 69 KESIWFMMLSYLYWFSIFSFYIYIFYRHEKKLYYRVCIKRMIEEIRYIANGNFNHKVSIV 128 Query: 113 TADELGLLAENINIMSERLQHSLLEERKTVAAKNELITGVSHDLRTPLTSVLGYLEYIEQ 172 D L LA +N + E+L+ S+ EER+T AK+ELIT VSHDLRTPLTS++GY+ I Sbjct: 129 QQDHLEELAIGVNQIVEQLKVSIEEERQTEQAKSELITNVSHDLRTPLTSIVGYVNLIHH 188 Query: 173 DRCREETELRYYVNIAYQKALVLQKLIDDLFEYTRVSSGGLPLVPERLDLKAFMRQLAEE 232 D R+E ELR+Y+ + Y K L L++DLFEYTRV + L L +D+ + QL + Sbjct: 189 DNYRDEVELRHYIQVIYDKVHRLNTLMNDLFEYTRVQNKELSLRSVPIDMIELLGQLTVQ 248 Query: 233 AVPELARAGMTYELVDETDSLWIQAAPYELLRAYENLITNAIRYGREGKRLEIGLSREGD 292 +L A + + L + A +L+R +ENLI NAI YG +GK ++I EG+ Sbjct: 249 FRIQLQEANIKCRPSYPSQKLMVLADGDKLVRVFENLIINAITYGSDGKYIDITAYEEGN 308 Query: 293 EAVVRISNFGERIAESDLPHIFERFYRAERSRSQYTGGSGLGLAIAKGIVERHKGVISAA 352 + ++N+G+ I +DLPHIFERFYR E+SRS YTGGSGLGLAIAK IVE H G I Sbjct: 309 LVAIDVTNYGQPIPSTDLPHIFERFYRVEKSRSAYTGGSGLGLAIAKSIVELHNGTIEVY 368 Query: 353 SDMYRTDFITR 363 SD +T F + Sbjct: 369 SDEEKTTFTVK 379 >C2KV58.1 C2KV58_9FIRM Sensor histidine kinase Length = 411 Score = 236 bits (602), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 141/355 (39%), Positives = 203/355 (57%), Gaps = 10/355 (2%) Query: 14 IWAFILSVVSGAILL-IGGYRLVNSLVYLNPSPPSAAYSQLLRWVINHIGSVPVMTAAGI 72 I A +V+ ++L IG Y N LV + P R+ S+ + GI Sbjct: 9 ISALFTAVIECFLVLNIGSY--TNYLVQIGNDNPLVQ-----RFAFVSTVSILLFVLVGI 61 Query: 73 LSFLFFFFIYTRKIVLYLEEITRGIQQITKLGESHR-IEVRTADELGLLAENINIMSERL 131 L F F RK +E + +G++QI+ G+ H I + EL +AE+I +M E L Sbjct: 62 LIFTIIFLFLQRKTARDIETLAQGVKQISA-GDFHTDIAISGEGELAHIAESIRLMEEEL 120 Query: 132 QHSLLEERKTVAAKNELITGVSHDLRTPLTSVLGYLEYIEQDRCREETELRYYVNIAYQK 191 + ER+ +K +LIT ++HDLRTPLTS+LGYL+ + + E ++Y+ I Y K Sbjct: 121 SSHIERERENEQSKTDLITNIAHDLRTPLTSILGYLDLLRNSQMVPEEMKKHYIEIVYNK 180 Query: 192 ALVLQKLIDDLFEYTRVSSGGLPLVPERLDLKAFMRQLAEEAVPELARAGMTYELVDETD 251 AL LQKLI++LF +T++S G L + LDL + QL EE+ P + ++Y+ Sbjct: 181 ALRLQKLIEELFGFTKLSYGKLNMNISTLDLVQLLSQLVEESYPNFEKNNLSYDFSANVK 240 Query: 252 SLWIQAAPYELLRAYENLITNAIRYGREGKRLEIGLSREGDEAVVRISNFGERIAESDLP 311 SL+I+ L R ++NLI+NAI+YG EGKR+ I L +E +E +V++ NFG I E +LP Sbjct: 241 SLFIEGDGDLLARLFDNLISNAIKYGAEGKRVLIRLRKEKEEVMVQVLNFGYVIPEKELP 300 Query: 312 HIFERFYRAERSRSQYTGGSGLGLAIAKGIVERHKGVISAASDMYRTDFITRYPL 366 IF++FYR E SRS TGG+GLGLAI K IV+ H G I+ SDM T F PL Sbjct: 301 LIFDKFYRVEHSRSLSTGGTGLGLAIVKNIVDMHHGNITVQSDMGGTRFNVTLPL 355 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.322 0.138 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,097,340,150 Number of extensions: 86882043 Number of successful extensions: 350507 Number of sequences better than 1.0e-05: 25232 Number of HSP's gapped: 318800 Number of HSP's successfully gapped: 25291 Length of query: 367 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 230 Effective length of database: 1,770,017,148 Effective search space: 407103944040 Effective search space used: 407103944040 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 132 (55.5 bits)