BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0564.0067.p (380 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A0LTA3.1 A0LTA3_ACIC1 Putative uncharacterized protein 139 6e-31 A6Q8N3.1 A6Q8N3_SULNB Putative uncharacterized protein 115 7e-24 A3CXD8.1 A3CXD8_METMJ Dipeptidyl aminopeptidase/acylaminoacyl-pe... 108 6e-22 A3CVQ9.1 A3CVQ9_METMJ Dipeptidyl aminopeptidase/acylaminoacyl-pe... 103 2e-20 B9L524.1 B9L524_THERP Putative uncharacterized protein 103 2e-20 >A0LTA3.1 A0LTA3_ACIC1 Putative uncharacterized protein Length = 357 Score = 139 bits (349), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 104/350 (29%), Positives = 151/350 (43%), Gaps = 11/350 (3%) Query: 23 QRWYGRFLLFGTDYGRLRRVVARVSDWHKWCEVWTAEGDEVYRKAEKALAEGSEGKARAL 82 + W RF G Y V++R++ W +WC W + AL EG A Sbjct: 11 ENWGPRFTTNGVTYSDFHEVLSRITTWEEWCSAWCTAAEPYVELGRAALDEGRTLSAGDH 70 Query: 83 FHEAVACYHAGQHIFFIDSRQKEAAQEKARNSYVQAISLYNDTEKPVRVDIPYRGVSIPG 142 F +A YH + +F D Q AA +KA A+ + + R+ +P+ G + G Sbjct: 71 FSQAAVYYHFAKFLFVDDMEQMRAAHQKAVECLTTALPYLDPPGR--RITVPFEGARMVG 128 Query: 143 YLRKADTKGR-PLIIFVNGMDNIKEAEGHHFGSVFNRQGFNFFTFDGPGQGEMWSSLKFD 201 LR + P ++ + G+D+ KE E +F ++G F+ DGPGQGE L Sbjct: 129 ILRLPRGEPPFPAVMLIPGLDSTKE-EFRSTEQLFLQRGLATFSVDGPGQGEAEYDLPIR 187 Query: 202 ARDYHKAVSAVIDWFEQQPPCGIDLGRIGLVGFSLGGYLAPEAAARDPRVKCTVGNSGLV 261 D+ +A++D QP ID R+G+ G SLGGY AP A+ D RVK + +G Sbjct: 188 P-DWEVPGAALLDALASQPE--IDPARLGIWGVSLGGYYAPRLASGDQRVKACIALAGPW 244 Query: 262 YIGGI-RGLKELNPIWQRGVTYITGCETLEAALPQFNYDIGDAPALRSPLLFYHAGRDEV 320 G GL EL R + E A Q D G A +R PLL RD + Sbjct: 245 NFGACWDGLNELTRAAFRVRSRSRSDEEARAKAAQLTLD-GRAERIRCPLLVVAGKRDRL 303 Query: 321 MPAPKTHADKMVNWAKGEKTLKYMEDAEHCTMNYLDEVFPEMLDWFMREL 370 + P A ++ A + L +E+ H MN + DW R L Sbjct: 304 I--PWQDAVRLAEAAGSQAELLLLENGNHGGMNVAAQHRQRSADWMARIL 351 >A6Q8N3.1 A6Q8N3_SULNB Putative uncharacterized protein Length = 422 Score = 115 bits (288), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 73/236 (30%), Positives = 118/236 (50%), Gaps = 13/236 (5%) Query: 33 GTDYGRLRRVVARV--SDWHKWCEVWTAEGDEVYRKAEKALAEGSEGKARALFHEAVACY 90 G D G V R+ SD W + W A + ++A+K L++G A+ + + Y Sbjct: 47 GADIGECLSTVRRIQESDNESWYKEWLATAKRLEKRADKFLSKGHMISAKEAYFRSSNYY 106 Query: 91 HAGQHIFFIDSRQKEAAQ--EKARNSYVQAISLYNDTEKPVR-VDIPYRGVSIPGYLRKA 147 + + + +K+RN++++A L ++KP++ V IP+ G ++PGYL Sbjct: 107 RTAEFFLHTNPNDPRIVKTWKKSRNTFLKAAKL---SKKPIKFVKIPFEGTTLPGYLCLV 163 Query: 148 DTKG--RPLIIFVNGMDNIKEAEGHHFGSVFNRQGFNFFTFDGPGQGEMWSSLKFDAR-D 204 D G RPL+I +G D E G + + FN F+GPGQGE+ K R + Sbjct: 164 DNSGKKRPLLIIHSGFDGTAEELYFEIGHLAVEREFNVLLFEGPGQGEVIRVQKIPFRPN 223 Query: 205 YHKAVSAVIDWFEQQPPCGIDLGRIGLVGFSLGGYLAPEAAARDPRVKCTVGNSGL 260 + V+ V+D+ P ++ RIGL+G S GGYLAP A + + R+ V N G+ Sbjct: 224 WESVVTPVVDFALTLPE--VNPKRIGLIGISFGGYLAPRAVSFEHRINLCVANGGV 277 >A3CXD8.1 A3CXD8_METMJ Dipeptidyl aminopeptidase/acylaminoacyl-peptidase related protein Length = 474 Score = 108 bits (271), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 77/249 (30%), Positives = 113/249 (45%), Gaps = 12/249 (4%) Query: 23 QRWYGRFLLFGTDYGRLRRVVARV--SDWHKWCEVWTAEGDEVYRKAEKALAEGSEGKAR 80 QR G D G +R+ D+ W W A D +++LA G A Sbjct: 63 QRTLGASYSGEADIGECLATASRIREGDFESWYGEWKATADNFRAAGDESLAAGHRVTAM 122 Query: 81 ALFHEAVACYHAGQHIFFIDSRQKEAAQE--KARNSYVQAISLYNDTEKPVRVDIPYRGV 138 ++ A Y + ++ + +R + A++L D V IPY Sbjct: 123 EAYYRAATYYRTAEFFLHGNATDPRIVETWGMSREMFRNALAL--DAVPYEIVAIPYENT 180 Query: 139 SIPGYLRKADTKG--RPLIIFVNGMDNIKEAEGHHFGSVFNRQGFNFFTFDGPGQGEMWS 196 ++PGY D G RPL+I G D +E E H + R+G+N TF+GPGQGE+ Sbjct: 181 TLPGYFYAVDDSGEPRPLLIVQTGFDGCQE-ELHPYAMEGIRRGYNVLTFEGPGQGEVIR 239 Query: 197 SLKFDAR-DYHKAVSAVIDWFEQQPPCGIDLGRIGLVGFSLGGYLAPEAAARDPRVKCTV 255 + R D+ K + V+D+ +P +D GRI L G SLGGYLAP AA +PR+ V Sbjct: 240 VQQIPFRHDWEKVIGPVVDYAVSRP--DVDEGRIALWGISLGGYLAPRGAAYEPRIAALV 297 Query: 256 GNSGLVYIG 264 + G +G Sbjct: 298 ADGGTYDVG 306 >A3CVQ9.1 A3CVQ9_METMJ Dipeptidyl aminopeptidase/acylaminoacyl-peptidase related protein Length = 463 Score = 103 bits (258), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 102/406 (25%), Positives = 157/406 (38%), Gaps = 58/406 (14%) Query: 23 QRWYGRFLLFGTDYGRLRRVVARV--SDWHKWCEVWTAEGDEVYRKAEKALAEGSEGKAR 80 QR G D G +R+ D+ W W D +++LA G A Sbjct: 63 QRTLGASYSGEADVGECLATASRIKEGDFESWYCEWNRTADNFRAVGDESLAAGHRITAM 122 Query: 81 ALFHEAVACYHAGQHIFFIDSRQKEAAQE--KARNSYVQAISLYNDTEKPVRVDIPYRGV 138 ++ A Y + ++ + K+R S+ A++L D V +PY Sbjct: 123 EAYYRAATYYRTAEFFLHGNATDPRIVETWGKSRESFRDALAL--DVVPYEIVAVPYGNT 180 Query: 139 SIPGYLRKADTKG--RPLIIFVNGMDNIKEAEGHHFGSVFNRQGFNFFTFDGPGQGEMWS 196 ++PGY D G RPL+I G D +E E H + ++G+N TF+GPGQGE+ Sbjct: 181 TLPGYFYAVDDSGKPRPLLIVQTGFDGCQE-ELHPYAMEGIKRGYNVLTFEGPGQGEVIR 239 Query: 197 SLKFDAR-DYHKAVSAVIDWFEQQPPCGIDLGRIGLVGFSLGGYLAPEAAARDPRVKCTV 255 R D+ + V+D+ +P +D RI L G SLGGYLAP AA +PR+ + Sbjct: 240 VRHIPFRHDWENVIGPVVDYAVSRP--DVDEDRIALWGISLGGYLAPRGAAYEPRITALI 297 Query: 256 GNSGLVYI----------GGIRGLKEL-------------NPIWQRGVTYITGCETL-EA 291 + G + GG+ L E+ N + + + TG L E Sbjct: 298 ADGGTYDVGLNLLANLEAGGVANLTEIELQEWLQTDPVEFNDAIRGAMAHDTGTRWLNEN 357 Query: 292 ALPQFNYD--------------IGDAPALRSPLLFYHAGRDEVMPAPKTHADKMVNWAKG 337 + FN +G A +R P L D P A + + Sbjct: 358 GMFVFNAGSPARFWAKWMDFSLVGVAEEIRCPTLVCAGAVDHFDP-DGAQATALYDHLTC 416 Query: 338 EKTLKYMED----AEHCTMNYLDEVFPEMLDWFMRELRM---QPGQ 376 E+ L D HC + + F DW ++ M +PG+ Sbjct: 417 ERELMVFSDDYGAGSHCQLRAFAQSFGAKFDWLDDKMGMTDFRPGE 462 >B9L524.1 B9L524_THERP Putative uncharacterized protein Length = 503 Score = 103 bits (258), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 95/341 (27%), Positives = 147/341 (43%), Gaps = 31/341 (9%) Query: 28 RFLLFGTDYGRLRRVVARVSDWHKWCEVWT-AEGDEVYRKAEKALAEGSEGKARALFHEA 86 RFLL G L + RV H W W A D + E+A+A E + A + Sbjct: 168 RFLLAGIHPRSLTTTLRRVRRLHDWPRAWVRAAHDYLLAAHERAVA--GEVRLAAEYQRV 225 Query: 87 VA-CYHAGQHIFFIDSRQKEAAQEKARNSYVQAISLYNDT----EKPV-RVDIPYRGVSI 140 A CYH + D R ++ Y A+ L+ E+P+ ++IP+ G+++ Sbjct: 226 AALCYHFAHVLALGDHRYRQ-------QLYTSAVRLFRAAAPHLERPILPIEIPWHGIAL 278 Query: 141 PGYLRKADTKGRPLIIFVNGMDNIKEAEGHHFGSVFNRQGFNFFTFDGPGQGEMWSSLKF 200 PGYL + P+++F+NG +KE E + F +G D PG GE+ S+ Sbjct: 279 PGYLCLPSDRPAPVVVFLNGASTVKE-EMIGWAQPFLERGLAVLALDTPGSGEIADSVP- 336 Query: 201 DARDYHKAVSAVIDWFEQQPPCGIDLGRIGLVGFSLGGYLAPEAAARDPRVKCTVGNSGL 260 A A+++ P G+D RI L+G SL G A + A P V + Sbjct: 337 AAPGQEDVGWAIVEAARTLP--GVDPRRIALLGVSLRGAYAVQLAHAVPEFAAAVAVTAP 394 Query: 261 V----YIGGIRGLKELNPIWQRGVTYITGCETLEAALPQFNYDIGDAPALRSPLLFYHAG 316 Y+G + L + GVT E L P + + AP+LR+PLL AG Sbjct: 395 FDPQPYVGALGELVRHDVALAAGVT----PEDLPRLAPTLSLE-PIAPSLRTPLLVVGAG 449 Query: 317 RDEVMPAPKTHADKMVNWAKGEKTLKYMEDAEHCTMNYLDE 357 D V+ P + + ++ A K L + E A H +L++ Sbjct: 450 NDLVV--PPSESLRLYRAAGSIKHLLFFERANHVAFTHLEQ 488 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.322 0.139 0.441 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,473,386,959 Number of extensions: 110692508 Number of successful extensions: 230132 Number of sequences better than 1.0e-05: 149 Number of HSP's gapped: 230036 Number of HSP's successfully gapped: 149 Length of query: 380 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 243 Effective length of database: 1,770,017,148 Effective search space: 430114166964 Effective search space used: 430114166964 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 132 (55.5 bits)