BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0564.0035.p (470 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0Z5B3.1 C0Z5B3_BREBN Probable transcriptional regulator 473 e-131 C0ZKE4.1 C0ZKE4_BREBN Probable transcriptional regulator 362 5e-98 C2W3X2.1 C2W3X2_BACCE Transcriptional regulator, GntR 359 3e-97 C2XP85.1 C2XP85_BACCE Transcriptional regulator, GntR 357 1e-96 C2PR38.1 C2PR38_BACCE Transcriptional regulator, GntR 355 8e-96 >C0Z5B3.1 C0Z5B3_BREBN Probable transcriptional regulator Length = 473 Score = 473 bits (1216), Expect = e-131, Method: Compositional matrix adjust. Identities = 240/454 (52%), Positives = 312/454 (68%), Gaps = 9/454 (1%) Query: 1 MLLVPNLSDTDRVPYYIQLYDYFKKAIISSSLPTGTRLPSIRILAAQLQLSTTPVELAYQ 60 MLL PN + D P Y+QLY Y KK I++ L ++LPS+R LA L LSTTPVE+AYQ Sbjct: 1 MLLTPNWQENDNDPQYVQLYAYLKKEIVAGRLAVSSKLPSVRKLADLLGLSTTPVEMAYQ 60 Query: 61 QLLSEGFIVSKPRSGYYVQQVHGLGGAAAEPDRSP---LTLRPITPRDSRTYPYDFHISR 117 QLL+EGFI SKPRSGY+V++ L +P P RP+ RD R Y YDFH+SR Sbjct: 61 QLLAEGFIQSKPRSGYFVEK---LPDPEVKPGADPSIHAIQRPML-RDEREYVYDFHLSR 116 Query: 118 NDFSLFPDKIWRSLYQEQL--ANPDLLQYGDPQGEPALRESIAAHLRQFRGLRCTAEQVV 175 NDFSLFP IWR LY E L + L YGDPQGE LR IA +LR++RG+ C+ QVV Sbjct: 117 NDFSLFPTMIWRRLYNETLHIDQQENLFYGDPQGEAGLRSQIADYLRRYRGVACSPNQVV 176 Query: 176 IGGDQYTLCSLLALLLQEKAMKLAIENPGYHLLPAAFQRHGFQILPLQLQEDGLDVTQLY 235 IG DQ+ L SL+ L+++ + ++ +ENPGY L F++HG+ ++P+ L EDG++V +LY Sbjct: 177 IGADQFGLLSLICLMVKPQFQRIGVENPGYLLFANTFRQHGYDVVPISLTEDGINVRELY 236 Query: 236 ASGANAVYLSPSHQFPRGMVMPIAKRLALLEWARANNGYIIEDDYDGEFRYHGRPIPALQ 295 S +S +HQ+PRGM+MPI+KRL LLEWA++ GYIIEDDYDGEFRYHGRPIP++Q Sbjct: 237 DSKVRLAAVSSAHQYPRGMIMPISKRLQLLEWAKSVGGYIIEDDYDGEFRYHGRPIPSMQ 296 Query: 296 GLLEDSPVIYMCSFAQSLAPALCIHYMVLPKPLVPDYHRLKSELYLEHSASRLNQIALHY 355 GLL + VIYM SFAQ LAPAL I YMVLP+ L+ Y+ L E LE S+SRL+Q + Sbjct: 297 GLLPHANVIYMGSFAQVLAPALGIWYMVLPESLLDTYYNLLRETLLEPSSSRLHQRTMEA 356 Query: 356 FMERGHFAKHLRRMRLVYQRKHDLLLNAIQQHFGETAAVHGQGAGFHILLALRSGGSARQ 415 FME+G+F KH+R+MR +Y++KHD LL A+ +HFG+ A V G AGFH+LL + S S + Sbjct: 357 FMEKGYFEKHVRKMRKLYRKKHDELLLAVHKHFGKRATVIGADAGFHVLLRVNSERSEEE 416 Query: 416 LAEKAAAAGIRVTPMSYTWWSGPEHDAPEFILGF 449 L + A AG+R + S+TW P EF LGF Sbjct: 417 LKKLAIQAGVRASSASFTWLVPPNPLPKEFFLGF 450 >C0ZKE4.1 C0ZKE4_BREBN Probable transcriptional regulator Length = 486 Score = 362 bits (929), Expect = 5e-98, Method: Compositional matrix adjust. Identities = 193/446 (43%), Positives = 270/446 (60%), Gaps = 14/446 (3%) Query: 14 PYYIQLYDYFKKAIISSSLPTGTRLPSIRILAAQLQLSTTPVELAYQQLLSEGFIVSKPR 73 P Y+QLY YF I L +GTRLPS+R L+ LQ+S T VE AY QL++EG+I S+ R Sbjct: 14 PLYLQLYRYFCTEIQGRRLISGTRLPSVRALSGFLQVSKTTVESAYHQLMAEGYIESRER 73 Query: 74 SGYYVQQVHGLG------GAAAEPDRSPLTLRPITPRDSRTYP--YDFHISRNDFSLFPD 125 SG+YV V G G +P ++ ITP P YDFH +R D FP Sbjct: 74 SGFYVVDVDWDGPVPVPTGKGQQPAKTAYV--QITPSTPSAVPIQYDFHQARVDAEHFPF 131 Query: 126 KIWRSLYQE--QLANPDLLQYGDPQGEPALRESIAAHLRQFRGLRCTAEQVVIGGDQYTL 183 WR + Q N +L YGD QGEP LRE +A +L + RG++ T EQ+VIG + Sbjct: 132 DRWRKYTNQCMQEENKHVLYYGDRQGEPQLREELARYLGRARGVQATPEQIVIGAGTQVI 191 Query: 184 CSLLALLLQEKAMKLAIENPGYHLLPAAFQRHGFQILPLQLQEDGLDVTQLYASGANAVY 243 SLL L + +A+E PGYH + F G+ + P++L EDG+DV L SGA VY Sbjct: 192 ISLLGFLFGTRGQAVAMEEPGYHGVRTVFSHLGYDVRPIRLTEDGIDVEALSESGARLVY 251 Query: 244 LSPSHQFPRGMVMPIAKRLALLEWARANNGYIIEDDYDGEFRYHGRPIPALQGLLEDSPV 303 ++PSHQ P G+VMP AKRL LL WA YIIEDDYDGEFRYHG+PIP+LQGL V Sbjct: 252 ITPSHQDPSGIVMPYAKRLKLLHWANQTGSYIIEDDYDGEFRYHGKPIPSLQGLDTQGRV 311 Query: 304 IYMCSFAQSLAPALCIHYMVLPKPLVPDYHRLKSELYLEHSASRLNQIALHYFMERGHFA 363 IY+ +F+++L P++ + YMVLP+ L+ + ++ + SASR++Q L FM+ G + Sbjct: 312 IYLGTFSKALLPSIRMSYMVLPQALLAVFQEKLAD--FDQSASRIHQETLALFMKNGDWE 369 Query: 364 KHLRRMRLVYQRKHDLLLNAIQQHFGETAAVHGQGAGFHILLALRSGGSARQLAEKAAAA 423 +H+R+MR +Y++KH +LL +Q+ G + GQ AG + + ++S + +QL + AAA+ Sbjct: 370 RHIRKMRTLYRKKHGVLLQCLQEQLGAYIRIKGQDAGLSVTVEVKSESTPQQLTQFAAAS 429 Query: 424 GIRVTPMSYTWWSGPEHDAPEFILGF 449 G+RV P ++ W E+ P F GF Sbjct: 430 GVRVYPTAHKWIHPQENGLPAFQFGF 455 >C2W3X2.1 C2W3X2_BACCE Transcriptional regulator, GntR Length = 463 Score = 359 bits (922), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 193/451 (42%), Positives = 283/451 (62%), Gaps = 15/451 (3%) Query: 3 LVPNLSDTDRVPYYIQLYDYFKKAIISSSLPTGTRLPSIRILAAQLQLSTTPVELAYQQL 62 L PNL+ +++P Y+QLY+Y K I S +P T+LP+ R LA L++S VE AY+QL Sbjct: 4 LTPNLNMEEKIPLYVQLYEYIKAEIRSGKIPPLTKLPAKRKLATYLEVSKNTVESAYEQL 63 Query: 63 LSEGFIVSKPRSGYYVQQVHGLGGAAAEPDRSPLTLRPITPRDSRTYPYDFHISRNDFSL 122 L+EG+I S R+GY+V ++ + E + ++ + ++ + Y YDF + D + Sbjct: 64 LAEGYIESVSRTGYFVCEIEQMIHTVKERE----VVKEVLYKEQK-YKYDFTQTGVDANA 118 Query: 123 FPDKIWRSLYQE--QLANPDLLQYGDPQGEPALRESIAAHLRQFRGLRCTAEQVVIG-GD 179 FP I+R + E QL N DLL G PQGE +LRE IA +L + RG+RC+A Q+VIG G Sbjct: 119 FPFSIYRKISNEVWQLENKDLLFLGHPQGELSLREEIAKYLYESRGVRCSASQIVIGAGT 178 Query: 180 QYTLCSLLALLLQEKAMKLAIENPGYHLLPAAFQRHGFQILPLQLQEDGLDVTQLYASGA 239 Q+ + L LL K A+ENPGYH F++ + L L +DG+ +T+L S A Sbjct: 179 QFLIRMLFQLL---KGSHFAVENPGYHRKLVVFEKGEENVQMLSLDKDGICITELEDSHA 235 Query: 240 NAVYLSPSHQFPRGMVMPIAKRLALLEWARANNG-YIIEDDYDGEFRYHGRPIPALQGLL 298 N V+++PSHQFP GM+MPI +R+ LL+WA+ NG YIIEDDYD EFRY G+PIPALQGL Sbjct: 236 NVVFVTPSHQFPCGMIMPIKRRMQLLQWAQGENGRYIIEDDYDSEFRYSGKPIPALQGLD 295 Query: 299 EDSPVIYMCSFAQSLAPALCIHYMVLPKPLVPDYHRLKSELYLEHSASRLNQIALHYFME 358 + VIYM + +++L P+L + YMVLPK L+ Y L+ S SR++Q + F+ Sbjct: 296 TEGNVIYMGTLSKALLPSLRMSYMVLPKQLIELYQ--TQYLFYAQSVSRIDQEIIRRFLN 353 Query: 359 RGHFAKHLRRMRLVYQRKHDLLLNAIQQHFGETAAVHGQGAGFHILLALRSGGSARQLAE 418 GH+ KH+ +MR+VY++K D L++AI+++F A V G+ +G HILL + +G L + Sbjct: 354 EGHWEKHIYKMRVVYRKKRDALVSAIERYFSNKAEVIGEDSGLHILLKVHNGMLEEALIK 413 Query: 419 KAAAAGIRVTPMSYTWWSGPEHDAPEFILGF 449 +AA GI+V P+S T++ +LGF Sbjct: 414 RAAENGIKVYPVS-TYYKEGTISKNTVLLGF 443 >C2XP85.1 C2XP85_BACCE Transcriptional regulator, GntR Length = 475 Score = 357 bits (916), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 191/454 (42%), Positives = 271/454 (59%), Gaps = 21/454 (4%) Query: 3 LVPNLSDTDRVPYYIQLYDYFKKAIISSSLPTGTRLPSIRILAAQLQLSTTPVELAYQQL 62 L PNLS + Y+QLY+Y KK I ++P T+LP+ R LA LQ+S VE AY+QL Sbjct: 13 LTPNLSANSKTALYVQLYEYIKKEIKDGTIPAFTKLPAKRKLATYLQVSKNTVEAAYEQL 72 Query: 63 LSEGFIVSKPRSGYYV----QQVHGLGGAAAEPDRSPLTLRPITPRDSRTYPYDFHISRN 118 L+EG+I S R GY+V Q +H G + P + Y +DF + Sbjct: 73 LAEGYIESISRKGYFVCEIEQMIHVEGSEEVIGE---------APFQDKKYKFDFTQTGV 123 Query: 119 DFSLFPDKIWRSLYQE--QLANPDLLQYGDPQGEPALRESIAAHLRQFRGLRCTAEQVVI 176 D + FP ++R + E Q N DLL G PQGE +LRE IA++L + RG+RC A Q+VI Sbjct: 124 DTNTFPFHVYRKITNEVWQFENKDLLFIGHPQGEVSLREEIASYLYESRGVRCVASQIVI 183 Query: 177 GGDQYTLCSLLALLLQEKAMKLAIENPGYHLLPAAFQRHGFQILPLQLQEDGLDVTQLYA 236 G L +L LL K + A+ENPGYH F++ + L L DG+ ++QL Sbjct: 184 GAGTQILVKMLFQLL--KGSRYAVENPGYHRKMVVFEQGEQNVQMLSLDRDGIRMSQLVD 241 Query: 237 SGANAVYLSPSHQFPRGMVMPIAKRLALLEWARANNG-YIIEDDYDGEFRYHGRPIPALQ 295 S AN V+++PSHQFP GM+MPI +R+ LL+WA+ G YIIEDDYD EFRY G+PIPALQ Sbjct: 242 SHANVVFVTPSHQFPYGMIMPITRRMQLLQWAKKEEGRYIIEDDYDSEFRYSGKPIPALQ 301 Query: 296 GLLEDSPVIYMCSFAQSLAPALCIHYMVLPKPLVPDYHRLKSELYLEHSASRLNQIALHY 355 GL D VIYM + +++L P+L + YMVLPK L+ Y + L+ S SR++Q + Sbjct: 302 GLDRDGKVIYMGTLSKALLPSLRMSYMVLPKQLIKQYQ--EQYLFYTQSVSRMDQEIIRK 359 Query: 356 FMERGHFAKHLRRMRLVYQRKHDLLLNAIQQHFGETAAVHGQGAGFHILLALRSGGSARQ 415 F+ GH+ KH+ +MR+VY++K D L++ I+++F V G+ +G HILL + +G ++ Sbjct: 360 FLNDGHWEKHIHKMRVVYRKKRDRLVSVIEKYFSSRIEVIGEDSGLHILLRVHNGMEEKE 419 Query: 416 LAEKAAAAGIRVTPMSYTWWSGPEHDAPEFILGF 449 L E AA I+V P+S + G + +LGF Sbjct: 420 LMETAAERSIKVYPVSMYYKEGTSPKST-VLLGF 452 >C2PR38.1 C2PR38_BACCE Transcriptional regulator, GntR Length = 466 Score = 355 bits (910), Expect = 8e-96, Method: Compositional matrix adjust. Identities = 188/454 (41%), Positives = 274/454 (60%), Gaps = 21/454 (4%) Query: 3 LVPNLSDTDRVPYYIQLYDYFKKAIISSSLPTGTRLPSIRILAAQLQLSTTPVELAYQQL 62 L PNL+ + Y+QLY+Y KK I ++P T+LP+ R LA LQ+S VE AY+QL Sbjct: 4 LTPNLNANSKTALYVQLYEYIKKEIKDGTIPALTKLPAKRKLATYLQVSKNTVEAAYEQL 63 Query: 63 LSEGFIVSKPRSGYYV----QQVHGLGGAAAEPDRSPLTLRPITPRDSRTYPYDFHISRN 118 L+EG+I S R GY+V Q +H G + P + Y +DF + Sbjct: 64 LAEGYIESISRKGYFVCEIEQMIHVEGSEEVIGE---------APFQDKEYKFDFTQTGV 114 Query: 119 DFSLFPDKIWRSLYQE--QLANPDLLQYGDPQGEPALRESIAAHLRQFRGLRCTAEQVVI 176 D + FP ++R + E QL N +LL G PQGE +LRE IA+++ + RG+RC+A Q+VI Sbjct: 115 DTNTFPFHVYRKITNEVWQLENKELLFLGHPQGEVSLREEIASYIYESRGVRCSASQIVI 174 Query: 177 GGDQYTLCSLLALLLQEKAMKLAIENPGYHLLPAAFQRHGFQILPLQLQEDGLDVTQLYA 236 G L LL LL K A+ENPGYH F++ + L L +DG+ +++L Sbjct: 175 GAGTQILVKLLFQLL--KGSGYAVENPGYHRKMVVFEQGEQNVQMLSLDKDGICISELEN 232 Query: 237 SGANAVYLSPSHQFPRGMVMPIAKRLALLEWARANNG-YIIEDDYDGEFRYHGRPIPALQ 295 S AN V+++PSHQFP GM+MPI +R+ LL+W++ + G YIIEDDYD EFRY G+PIPALQ Sbjct: 233 SSANIVFVTPSHQFPYGMIMPITRRMQLLQWSKKDEGRYIIEDDYDSEFRYSGKPIPALQ 292 Query: 296 GLLEDSPVIYMCSFAQSLAPALCIHYMVLPKPLVPDYHRLKSELYLEHSASRLNQIALHY 355 GL D VIYM + +++L P+L + YMVLPKPL+ Y + L+ S SR++Q + Sbjct: 293 GLDRDGKVIYMGTLSKALLPSLRMSYMVLPKPLIKQYQ--EQYLFYTQSVSRMDQEIIRK 350 Query: 356 FMERGHFAKHLRRMRLVYQRKHDLLLNAIQQHFGETAAVHGQGAGFHILLALRSGGSARQ 415 F+ GH+ KH+ +MR+VY++K D L++ ++++F V G+ +G HILL + +G ++ Sbjct: 351 FLNDGHWEKHIHKMRVVYRKKRDRLVSVLEKYFSNRIEVIGEDSGLHILLKVHNGMEEKE 410 Query: 416 LAEKAAAAGIRVTPMSYTWWSGPEHDAPEFILGF 449 L E AA I+V P S + G + +LGF Sbjct: 411 LMEAAAERSIKVYPASIYYKEGTSPKST-VLLGF 443 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.139 0.424 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,893,957,322 Number of extensions: 125713817 Number of successful extensions: 301728 Number of sequences better than 1.0e-05: 3803 Number of HSP's gapped: 292472 Number of HSP's successfully gapped: 3811 Length of query: 470 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 331 Effective length of database: 1,751,175,118 Effective search space: 579638964058 Effective search space used: 579638964058 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 133 (55.8 bits)