BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0564.0025.p (491 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K4W7.1 B3K4W7_9BACI Histidine kinase internal region 155 1e-35 B1D5I5.1 B1D5I5_9BACL Histidine kinase internal region 149 5e-34 B1DAF1.1 B1DAF1_9BACL Integral membrane sensor signal transducti... 147 2e-33 B0G6M3.1 B0G6M3_9FIRM Putative uncharacterized protein 141 2e-31 A5KK62.1 A5KK62_9FIRM Putative uncharacterized protein 140 2e-31 >B3K4W7.1 B3K4W7_9BACI Histidine kinase internal region Length = 599 Score = 155 bits (391), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 120/468 (25%), Positives = 219/468 (46%), Gaps = 16/468 (3%) Query: 27 SSFPWFDQRVSLDNDYLHWNVTADFHTNSSSGASSNALYVSKNIIRDNRSLGLLVIEMNG 86 S PW D+ V ++ H S+A+ + + I + ++G++++++N Sbjct: 138 SGGPWLDKTVLGSPMMVYMLHNGSRHAYFKQSGVSDAITIGREIRYNRETIGVVMVDLNY 197 Query: 87 SLIERLLNRAQIHAQNAVFIVSGEGQLLFRNENMLKPLQEDAELFSTATQILKRGDDHGT 146 I++ + + ++++ +G ++ E+ + Q L D Sbjct: 198 DFIQKTYG-VKPTTDSMIYVLDKQGGFVYEAESA-PAFAPSFDKILRIHQDLAGNGDAIK 255 Query: 147 QNISWAGSPYYLIYKQISSTPWTMFSLIPMYSFHSDSMNIWHTTAITTAISVVLIAAFFC 206 Q+I G Y ++ +Q T W+ +LIPM S S+S + A + I +++ Sbjct: 256 QSID--GRDYIVVSRQSGYTGWSTLALIPMDSLLSESARLRKLLAEVSIIVFIVVLIASL 313 Query: 207 VLYLKVTLPIAQLSRIVRKAGQGQTPETYAYKGFK---EIETLNRGXXXXXXXXXXXXXT 263 + ++TL I +L ++ +G T+ K K E L R Sbjct: 314 QVSSRITLNIRRLKSLMMFVKEGNL--TFPKKEIKSEDETGQLYRVFISMVEDLKRLLEG 371 Query: 264 IKRGENEKRKLELHRLQEQMRPHFWHNSLNSLRFLAVLNGDNQMAEAILSLTRMLDYTLR 323 I+ E EKR+ EL LQ Q+ PHF +NSLN++++LA +NG + E SL ++ L Sbjct: 372 IRVSEKEKREAELTALQAQIHPHFLYNSLNTIKYLAKMNGVPNIEEVSGSLIELMRGVLG 431 Query: 324 NTDVLYSTLEEEKDYAMSFVRFQEIRSMQQIRVNLEL-DERAMQAQIPKFTLQLILENSI 382 N+ + T+ EE DY ++ + R M+ IR+ ++ DE ++ ++ K LQ ++EN+I Sbjct: 432 NSSE-FLTVREELDYVERYISIVKYRYMEPIRMVTQVEDETLLECRVLKLMLQPLVENAI 490 Query: 383 MHGFAAPFDKEP--WIRVVAETEDELLILRITDNGNGMDQATLQRLFQPERKQHRARRSS 440 +HG P ++E IRV E D L + + DNG GM +L K R S Sbjct: 491 IHGI-GPLEQEGLVLIRVCEEGSD--LKIEVIDNGKGMTAGQQAQLLGETGKNGNTSRFS 547 Query: 441 GLSLINLQQRFRLEYGSGFGIRVASEHGQFTEVTMTLPLMTTDNEQER 488 G+ + N+ +R YG G+G+++ SE G +T+ + LP + + ++ R Sbjct: 548 GMGVRNVHERIVHMYGDGYGVKLYSEPGFYTKAEIRLPNIVENKDKSR 595 >B1D5I5.1 B1D5I5_9BACL Histidine kinase internal region Length = 602 Score = 149 bits (377), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 114/458 (24%), Positives = 222/458 (48%), Gaps = 14/458 (3%) Query: 30 PWFDQRV--SLDNDYLHWNVTADFHTNSSSGASSNALYVSKNIIRDNRSLGLLVIEMNGS 87 PW D+ V + DY+ N H + + V + I + +++G++++++N Sbjct: 141 PWLDRSVLGTPMMDYMLRN--GSRHAYLKQTGVTETITVGREIRYNRQTIGVVMVDLNYD 198 Query: 88 LIERLLNRAQIHAQNAVFIVSGEGQLLFRNENMLKPLQEDAELFSTATQILKRGDDHG-T 146 I + + A + ++++ + + ++R+++ D ++ + K G G Sbjct: 199 FIRKTYG-VRPTADSMLYVLDQQDEFVYRSDHTPSFAPSDQKIVDMKRKFAKLGKVEGDV 257 Query: 147 QNISWAGSPYYLIYKQISSTPWTMFSLIPMYSFHSDSMNIWHTTAITTAISVVLIAAFFC 206 + G Y ++ +Q T W+ +LIP S S+S + I A +VL+ Sbjct: 258 EERVIGGRSYIVVSRQSDHTGWSTLALIPTDSLLSESARLLK--LIIEASVIVLLVVLIG 315 Query: 207 VLYL--KVTLPIAQLSRIVRKAGQGQ-TPETYAYKGFKEIETLNRGXXXXXXXXXXXXXT 263 L + ++T+ I +L ++ G T E+ L Sbjct: 316 SLQVSSRITINIRRLKSMMMLVKDGNLTLPKKEIAAKDEVGQLYHVFIGMVEELKRLFEG 375 Query: 264 IKRGENEKRKLELHRLQEQMRPHFWHNSLNSLRFLAVLNGDNQMAEAILSLTRMLDYTLR 323 I+ E EKR+ EL LQ Q+RPHF +NSLN++++LA LNG + E SL ++ L Sbjct: 376 IRVSEQEKREAELTALQAQIRPHFLYNSLNTIKYLAKLNGTPNIEEVSGSLIDLMRGVLG 435 Query: 324 NTDVLYSTLEEEKDYAMSFVRFQEIRSMQQIRVNLEL-DERAMQAQIPKFTLQLILENSI 382 N++ Y T+ EE DY S++ + + M+ I V+ E+ D + +++ K TLQ I+EN++ Sbjct: 436 NSNE-YLTVREELDYVRSYISIVKYKYMEPIIVHEEIEDPSLLDSRVLKLTLQPIVENAV 494 Query: 383 MHGFAAPFDKEPWIRVVAETEDELLILRITDNGNGMDQATLQRLFQPERKQHRARRSSGL 442 +HG + ++ ++ + ++ L++ +TDNG GM +++L + + + R SG+ Sbjct: 495 LHGIGSR-EQGGFVTIRVYEDNRDLMIEVTDNGKGMTPEQMEQLLGGQGTKPTSSRFSGM 553 Query: 443 SLINLQQRFRLEYGSGFGIRVASEHGQFTEVTMTLPLM 480 + N+ +R + + +GIR+ SE G +T+V + P M Sbjct: 554 GVRNVHERIVRSFEAPYGIRLYSEPGLYTKVEIRFPNM 591 >B1DAF1.1 B1DAF1_9BACL Integral membrane sensor signal transduction histidine kinase Length = 596 Score = 147 bits (371), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 103/406 (25%), Positives = 190/406 (46%), Gaps = 12/406 (2%) Query: 76 SLGLLVIEMNGSLIERLLNRAQIHAQNAVFIVSGEGQLLFRNENMLKPLQEDAELFSTAT 135 ++G + ++ + +IE ++ I+ G+ + + ++++L T Sbjct: 195 TIGYVAVDADIHVIEDVVQELNTVTNGKTLIIDGQNNVAYDSDHVLTATN------ITGN 248 Query: 136 QILKRG-DDHGTQNISWAGSPYYLIYKQISSTPWTMFSLIPMYSFHSDSMNIWHTTAITT 194 ++++R D G+ N+ GS Y Y T W +F+ +P+ H D+ + +TT Sbjct: 249 EVIQRAVGDQGSFNVVVDGSSYICSYSVSKDTGWKIFAFVPVDYLHHDA-QLTRNVTLTT 307 Query: 195 AISVVLIAAFFCV-LYLKVTLPIAQLSRIVRKAGQGQTPETYAYKGFKEIETLNRGXXXX 253 I ++ A V L +T + Q++ ++R G ++ K E+ L Sbjct: 308 TIGIIGFALLVSVILAFMMTRSLRQMTDLMRTVRGGNLDVSFDVKQKDEVGILGTEFNRM 367 Query: 254 XXXXXXXXXTIKRGENEKRKLELHRLQEQMRPHFWHNSLNSLRFLAVLNGDNQMAEAILS 313 I ++ K++ +L LQ Q+ PHF +N+L ++R A +N D ++AE + Sbjct: 368 LRRMKELISEIYVIQSRKKEADLEALQSQINPHFIYNTLETIRMTAEINDDEEVAEMTFT 427 Query: 314 LTRMLDYTLRNTDVLYSTLEEEKDYAMSFVRFQEIRSMQQIRVNLELDERAMQAQIPKFT 373 L ++L Y++ N L EE + +++ R + V ++ + M + K T Sbjct: 428 LGKLLRYSI-NRGRETVELREELQHLERYLQLLRYRFSNRFVVAFDIPQELMNFPVMKLT 486 Query: 374 LQLILENSIMHGFAAPFDKEPWIRVVAETEDELLILRITDNGNGMDQATLQRLFQP-ERK 432 Q I+EN+I+HG E IR+ AE +++LLI I D G GMD TL L Q Sbjct: 487 FQPIVENAILHGMEGK-PNEVTIRLSAELKEQLLIFSIKDEGAGMDGMTLDLLRQAMNGT 545 Query: 433 QHRARRSSGLSLINLQQRFRLEYGSGFGIRVASEHGQFTEVTMTLP 478 + A +G+ L N+ +R +L YG +G+ + S+ G+ T V + LP Sbjct: 546 RESASSKTGVGLRNVNERIKLHYGETYGLEIESKWGEGTTVNLKLP 591 >B0G6M3.1 B0G6M3_9FIRM Putative uncharacterized protein Length = 612 Score = 141 bits (355), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 106/408 (25%), Positives = 192/408 (47%), Gaps = 11/408 (2%) Query: 73 DNRSLGLLVIEMNGSLIERLLNRAQIHAQNAVFIVSG-EGQLLFRNENMLKPLQEDAELF 131 D G+L+++M S++E +L + + + V +G+LL+ + + D ELF Sbjct: 187 DRPGSGVLLVDMKYSVVENVLKQINESSDGVYYYVCNRDGELLYHP----RRAEIDRELF 242 Query: 132 STATQILKRGDDHGTQNISWAGSPYYLIYKQISSTPWTMFSLIPMYSFHSDSMNIWHTTA 191 + + G + G IS +I IS T W + +IP ++ N + Sbjct: 243 KENS-LKAAGYEDGVYEISSGNGKENVIVGSISYTGWKLIGVIPESVQTANINNFRYYIF 301 Query: 192 ITTAISVVLIAAFFCVLYLKVTLPIAQLSRIVRKAGQGQTPETYAYKGFKEIETLNRGXX 251 T I ++L+ ++ KV+ PI +L V+ G+ P+ Y G E+ L Sbjct: 302 TTIIILMMLLLEGNRLISQKVSKPIRELDASVKAYEAGEKPDIYI-GGSLEVRHLGHSVQ 360 Query: 252 XXXXXXXXXXXTIKRGENEKRKLELHRLQEQMRPHFWHNSLNSLRFLAVLNGDNQMAEAI 311 I R +NE+RK EL LQ Q+ PHF +N+L S+ ++ + + I Sbjct: 361 KSYEQIEQLMEEIMRQQNERRKSELDALQSQINPHFLYNTLESITWMVEAQKNREAVIMI 420 Query: 312 LSLTRMLDYTLRNTDVLYSTLEEEKDYAMSFVRFQEIRSMQQIRVNLELDERAMQAQIPK 371 L ++L +L + +++E ++ S++ Q +R ++ +++ ++DE I K Sbjct: 421 SELAKLLRVSLSRGKTII-PIKDELQHSRSYMNIQLVRYKERFKIDFQIDEELYNYCIVK 479 Query: 372 FTLQLILENSIMHGFA-APFDKEPWIRVVAETEDELLILRITDNGNGMDQATLQRLFQPE 430 +Q ILEN+I +G D + I V E +D + + I DNG GM + L+ + Sbjct: 480 LVIQPILENAIYYGVGHMDEDDDGRIVVSGEKKDNDIYISIEDNGMGMRKEVLENILTDN 539 Query: 431 RKQHRARRSSGLSLINLQQRFRLEYGSGFGIRVASEHGQFTEVTMTLP 478 K + SG+ +IN+ R +L +G G+G+ V SE + T+V + +P Sbjct: 540 NKV--PKHGSGVGVINVHSRIKLMFGEGYGLTVYSEPDEGTKVVIHIP 585 >A5KK62.1 A5KK62_9FIRM Putative uncharacterized protein Length = 634 Score = 140 bits (354), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 110/415 (26%), Positives = 202/415 (48%), Gaps = 19/415 (4%) Query: 78 GLLVIEMNGSLIERLLNRAQIHAQNA---VFIVSGEGQLLFRNENMLKPLQ-EDAELFST 133 G+L+++M+ + I R++N QI+ N ++ G++++ P Q + + S Sbjct: 212 GVLLVDMDYADISRMMN--QINTLNNGEYYYLCDSNGEIIYH------PRQIQISNGLSG 263 Query: 134 ATQILKRGDDHGTQNISWAGSPYYLIYKQISSTPWTMFSLIPMYSFHSDSMNIWHTTAIT 193 L G + G +I IS T W + +IP +F +++ + + Sbjct: 264 ENSSLAASHKDGVYEDDFKGERRKVIVNTISYTGWKLVGVIPYSAFIHGMIDVRYFIILL 323 Query: 194 TAISVVLIAAFFCVLYLKVTLPIAQLSRIVRKAGQGQTPETYAYKGFKEIETLNRGXXXX 253 ++V+++ A V+ +++ PI +L+ V + G+ PE Y G +EI L Sbjct: 324 MLLTVMVLVALNRVVSARISSPILKLNASVLEYEAGEKPEVYI-GGAEEIRYLGYSIQKS 382 Query: 254 XXXXXXXXXTIKRGENEKRKLELHRLQEQMRPHFWHNSLNSLRFLAVLNGDNQMAEAILS 313 I +NE+RK EL LQ Q+ PHF +N+L+S+ ++ +++ A I Sbjct: 383 YEQIDELMKEIIIEQNERRKSELDALQSQINPHFLYNTLDSITWMIEDGRNDEAAFMISQ 442 Query: 314 LTRMLDYTLRNTDVLYSTLEEEKDYAMSFVRFQEIRSMQQIRVNLELDERAMQAQIPKFT 373 L ++ +L + + + +E +A S++ Q+IR V ++D+ I K Sbjct: 443 LAKLFRISLSKGHTVIN-IRDELQHARSYMNIQKIRYKNAFSVTFDVDDSLYAFCIVKLV 501 Query: 374 LQLILENSIMHGFAAPFDKEPWIRVVAETEDELLILRITDNGNGMDQATLQRLFQPERKQ 433 LQ ILEN+I +G D I++ + E+ L+IL +TDNG GM + RL E++ Sbjct: 502 LQPILENAINYGINGT-DDCGEIKISGKMENGLIILSVTDNGIGMCSEEVSRLLTDEKRV 560 Query: 434 HRARRSSGLSLINLQQRFRLEYGSGFGIRVASEHGQFTEVTMTLP--LMTTDNEQ 486 H + SG+ L+N+ R ++ +G +GI V SE + T V++ +P L T +N + Sbjct: 561 H--KHGSGVGLVNVNNRIKIVFGKEYGIVVESEPDEGTTVSICIPAVLYTEENRK 613 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.134 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,673,641,327 Number of extensions: 103474092 Number of successful extensions: 268922 Number of sequences better than 1.0e-05: 1860 Number of HSP's gapped: 266476 Number of HSP's successfully gapped: 1861 Length of query: 491 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 351 Effective length of database: 1,741,754,103 Effective search space: 611355690153 Effective search space used: 611355690153 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)