BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0564.0014.p (336 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DI61.1 B1DI61_9BACL Transcriptional regulator, LacI family 444 e-123 A9U828.1 A9U828_PHYPA Predicted protein (Fragment) 269 4e-70 B0K1M1.1 B0K1M1_THEPX Periplasmic binding protein/LacI transcrip... 177 1e-42 B0KDE9.1 B0KDE9_THEP3 Transcriptional regulator, LacI family 175 5e-42 Q8RD46.1 Q8RD46_THETN Transcriptional regulator 174 1e-41 >B1DI61.1 B1DI61_9BACL Transcriptional regulator, LacI family Length = 336 Score = 444 bits (1143), Expect = e-123, Method: Compositional matrix adjust. Identities = 210/332 (63%), Positives = 267/332 (80%) Query: 3 NIKEIAQLSGVSKSTVSRVISGSGYASQEARDKVLKVIQELQYKPNAVARAMVSQRTHNI 62 IKEIA+ +GVSKSTVSR+ISG+GY+S EARDKVL +++ELQYKPNAVARAMVSQRTHNI Sbjct: 5 TIKEIARRAGVSKSTVSRIISGNGYSSPEARDKVLGLVEELQYKPNAVARAMVSQRTHNI 64 Query: 63 GVLIYRREYPVASHPFYGKILDAILASASAMNYSVFVTTDHEMSLRSADFMLEKRVDGLI 122 GVL+YRR+ P+ASHPFYGKI+DA+L A+ +NYS+FVTTDH+MS RSADFM+EKRVDGLI Sbjct: 65 GVLLYRRDLPIASHPFYGKIVDAVLLEAARLNYSIFVTTDHDMSYRSADFMIEKRVDGLI 124 Query: 123 LISRLEQNVIDHIGKFGVPYIMVNGSTDVPGVIHIVNRDQDGGLEAARHLSGLGHRRIFM 182 LISRL+QNVIDHI FG+P++MVNGSTDV GVIHIVN+D++GG A L+ GH RIF+ Sbjct: 125 LISRLQQNVIDHITSFGIPFVMVNGSTDVDGVIHIVNQDEEGGRMVAEFLTQTGHERIFV 184 Query: 183 LAGPQSHRSHHLRLEGFRSYMNGQRAEFGGSDIAYLLSSTFEEGYRMMKEHWEHFQSRAY 242 +AGPQSHRSHHLRL+GF +++ + G + I +STF EGY +M W+ F+ Y Sbjct: 185 VAGPQSHRSHHLRLKGFMTFIRQAGIQEGDAAIRSAATSTFAEGYEIMSREWDQFREGGY 244 Query: 243 TAVFGTNDMIALGAMKFLMEHSVSVPGQVAVMGFDDNDVASILTPSLTTVRVDTEKMGRL 302 +A+F TNDM+A+GAMKFL E SV +P QV+V+GFDD D A++ +PSLTTV+VDT +MG Sbjct: 245 SALFATNDMLAMGAMKFLQEQSVRIPDQVSVVGFDDVDFAAMFSPSLTTVKVDTGEMGTQ 304 Query: 303 ACVMLDKLIRHEPVEETAVELEPQLVIRDSTR 334 + +LD+LIR E +L P+L++R STR Sbjct: 305 SVRLLDQLIRQEQNVVHPNQLVPRLIVRQSTR 336 >A9U828.1 A9U828_PHYPA Predicted protein (Fragment) Length = 168 Score = 269 bits (687), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 129/151 (85%), Positives = 141/151 (93%) Query: 4 IKEIAQLSGVSKSTVSRVISGSGYASQEARDKVLKVIQELQYKPNAVARAMVSQRTHNIG 63 I+EIAQL+GVSKSTVSRVISG GY E RD VLKVI+ELQYKPNAVARAMVSQRTHNIG Sbjct: 18 IREIAQLAGVSKSTVSRVISGKGYIHPETRDAVLKVIEELQYKPNAVARAMVSQRTHNIG 77 Query: 64 VLIYRREYPVASHPFYGKILDAILASASAMNYSVFVTTDHEMSLRSADFMLEKRVDGLIL 123 VLIYRREYP+ASHPFYGKI+DAILA+A++MNYSVFVTTDHEMSLRSADFMLEKRVDGLIL Sbjct: 78 VLIYRREYPIASHPFYGKIVDAILATAASMNYSVFVTTDHEMSLRSADFMLEKRVDGLIL 137 Query: 124 ISRLEQNVIDHIGKFGVPYIMVNGSTDVPGV 154 ISRL+QNVID+I FG+PY+MVNGSTDV V Sbjct: 138 ISRLQQNVIDYIHNFGIPYVMVNGSTDVDNV 168 >B0K1M1.1 B0K1M1_THEPX Periplasmic binding protein/LacI transcriptional regulator Length = 336 Score = 177 bits (449), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 113/345 (32%), Positives = 191/345 (55%), Gaps = 26/345 (7%) Query: 4 IKEIAQLSGVSKSTVSRVISG-SGYASQEARDKVLKVIQELQYKPNAVARAMVSQRTHNI 62 IK+IA+L+ VS +TVSRVI+ S S+E R+++L++++EL Y+PNA+AR +V+++T I Sbjct: 5 IKDIAKLANVSITTVSRVINNKSEGVSEETRNRILQLVKELGYQPNAIARGLVTKKTKTI 64 Query: 63 GVLIYRREYPVASHPFYGKILDAILASASAMNYSVFVT-TDHEMSLRSA--DFMLEKRVD 119 G++I P S+PF+ I + SA Y+VF+ TD + S + + EK VD Sbjct: 65 GLII-----PDISNPFFPDIARGVEDSAHIYGYNVFLCNTDDNLEKESEYINALKEKYVD 119 Query: 120 GLILISR--LEQNVIDHIGKFGVPYIMVNGSTDVPGVIHIVNRDQDGGLEAARHLSGLGH 177 G+I S + I + K G+P ++++ D + + + +GG A +HL LGH Sbjct: 120 GIIFTSSSIPKHEHIMELVKSGIPIVIMDRRVDSEDIYGVFLDNYEGGYIATKHLIDLGH 179 Query: 178 RRIFMLAGPQSHRSHHLRLEGFRSYM--NG----QRAEFGGSDIAYLLSSTFEEGYRMMK 231 ++I + GP +S RLEG++ + NG +R F G Y ++S +++ Sbjct: 180 KKIACITGPLYTKSAKERLEGYKKALVENGMDVDERLIFEGD---YKINSGIIGTEKLLG 236 Query: 232 EHWEHFQSRAYTAVFGTNDMIALGAMKFLMEHSVSVPGQVAVMGFDDNDVASILTPSLTT 291 + TA+F ND++A GA K + + +P ++++GFDD ++ IL P LTT Sbjct: 237 ------NNENVTAIFACNDLMAYGAYKTIRSYGYKIPDDISIVGFDDIQLSQILEPQLTT 290 Query: 292 VRVDTEKMGRLACVMLDKLIRHEPVEETAVELEPQLVIRDSTRRF 336 ++ MG A ML KL+ + +++ + PQL+IR ST+ Sbjct: 291 IKQPAYDMGLAAARMLIKLVEGKKLKKKIINFRPQLIIRQSTKNI 335 >B0KDE9.1 B0KDE9_THEP3 Transcriptional regulator, LacI family Length = 334 Score = 175 bits (444), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 112/342 (32%), Positives = 186/342 (54%), Gaps = 22/342 (6%) Query: 4 IKEIAQLSGVSKSTVSRVISGSGYA-SQEARDKVLKVIQELQYKPNAVARAMVSQRTHNI 62 IK+IA+L+ VS +TVSRVI+ S+E R+++L++++EL Y+PNA+AR +V+++T + Sbjct: 5 IKDIAKLANVSITTVSRVINNKTEGVSEETRNRILQLVKELGYQPNAIARGLVTKKTKTV 64 Query: 63 GVLIYRREYPVASHPFYGKILDAILASASAMNYSVFVT-TDHEMSLRSA--DFMLEKRVD 119 G++I P S+PF+ I + SA Y+VF+ TD + S + + EK VD Sbjct: 65 GLII-----PDISNPFFPDIARGVEDSAHIYGYNVFLCNTDDNLEKESEYINALKEKYVD 119 Query: 120 GLILISR---LEQNVIDHIGKFGVPYIMVNGSTDVPGVIHIVNRDQDGGLEAARHLSGLG 176 G+I S +++ D I K G+P ++++ D + + + +GG A ++L LG Sbjct: 120 GIIFTSSSIPKHEHITDLI-KSGIPVVIMDRRIDSEDIYGVFLDNYEGGYIATKYLIDLG 178 Query: 177 HRRIFMLAGPQSHRSHHLRLEGFRSYMNGQRAEFGGSDIAYLLSSTFEEGYRMMKE--HW 234 H+RI + GP + RLEG++ + E I FE Y++ Sbjct: 179 HKRIGCITGPLYISNAIERLEGYKRALVDNEIEVDNRLI-------FEGDYKINSGIIGA 231 Query: 235 EHFQSRAYTAVFGTNDMIALGAMKFLMEHSVSVPGQVAVMGFDDNDVASILTPSLTTVRV 294 E TA+F +ND++A GA K + + +P ++V+GFDD ++ IL P LTT+R Sbjct: 232 EKLLEHEVTAIFASNDLMAYGAYKAIRSYGYKIPDDISVVGFDDIQLSQILEPQLTTIRQ 291 Query: 295 DTEKMGRLACVMLDKLIRHEPVEETAVELEPQLVIRDSTRRF 336 MG A ML KL+ + +++ + PQL+IR ST+ Sbjct: 292 PAYDMGLAAARMLIKLVEGKKLKKKIINFRPQLIIRQSTKNI 333 >Q8RD46.1 Q8RD46_THETN Transcriptional regulator Length = 338 Score = 174 bits (441), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 110/344 (31%), Positives = 192/344 (55%), Gaps = 28/344 (8%) Query: 4 IKEIAQLSGVSKSTVSRVISGSGYA-SQEARDKVLKVIQELQYKPNAVARAMVSQRTHNI 62 IK+IA+L+ VS +TVSRVI+ S+E R K+LK+++EL Y+PNA+AR +V+++T I Sbjct: 5 IKDIARLANVSVTTVSRVINNKPEGVSEETRQKILKLVKELGYQPNAIARGLVTKKTKTI 64 Query: 63 GVLIYRREYPVASHPFYGKILDAILASASAMNYSVFVTTDHEMSLRSADF---MLEKRVD 119 G++I P S+PF+ I + SA Y+VF+ + + +++ + EK VD Sbjct: 65 GLII-----PDISNPFFPDIARGVEDSAHIYGYNVFLCNTDDNLEKESEYIRALKEKYVD 119 Query: 120 GLILISR---LEQNVIDHIGKFGVPYIMVNGSTDVPGVIHIVNRDQDGGLEAARHLSGLG 176 G+I S +++I+ + + G+P ++++ D + + + +GG A +HL LG Sbjct: 120 GIIFTSSSIPKHEHIIELV-ESGIPVVIMDRRVDSENIYGVFLDNYEGGYIATKHLIDLG 178 Query: 177 HRRIFMLAGPQSHRSHHLRLEGFRSYM--NGQRAE----FGGSDIAYLLSSTFEEGYRMM 230 H +I + GP +S RLEG++ + +G + + F G Y ++ R++ Sbjct: 179 HEKIGCITGPLYTKSAKERLEGYKKALLDSGIKIDEKLIFEGD---YKINGGIIGAERLL 235 Query: 231 KEHWEHFQSRAYTAVFGTNDMIALGAMKFLMEHSVSVPGQVAVMGFDDNDVASILTPSLT 290 K++ + +A+F ND++A GA K + +P ++V+GFDD ++ IL P L+ Sbjct: 236 KDN------KDMSAIFACNDLMAYGAYKTIRSFGYKIPDDISVVGFDDIQLSQILEPQLS 289 Query: 291 TVRVDTEKMGRLACVMLDKLIRHEPVEETAVELEPQLVIRDSTR 334 T++ MG A ML KLI + +++ + PQLVIR ST+ Sbjct: 290 TIKQPAYDMGLTAARMLIKLIEGKKLKKKIINFRPQLVIRQSTK 333 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.135 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,855,324,163 Number of extensions: 73384599 Number of successful extensions: 226488 Number of sequences better than 1.0e-05: 8637 Number of HSP's gapped: 212771 Number of HSP's successfully gapped: 8722 Length of query: 336 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 200 Effective length of database: 1,779,438,163 Effective search space: 355887632600 Effective search space used: 355887632600 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 131 (55.1 bits)