BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0560.0025.p (4011 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A5YBV1.2 A5YBV1_PAEPO Fusaricidin synthetase 1614 0.0 A9LJA2.1 A9LJA2_PAEPO FusA 1595 0.0 C3HA00.1 C3HA00_BACTU Phenylalanine racemase 1585 0.0 B1A907.1 B1A907_PAEPO Fusaricidin synthetase (Fragment) 1578 0.0 C3H9Z8.1 C3H9Z8_BACTU Glutamate racemase 1569 0.0 >A5YBV1.2 A5YBV1_PAEPO Fusaricidin synthetase Length = 7908 Score = 1614 bits (4180), Expect = 0.0, Method: Compositional matrix adjust. Identities = 873/2238 (39%), Positives = 1311/2238 (58%), Gaps = 62/2238 (2%) Query: 1801 ILDKDMHPSPVGVPGEVYLARL-------TEPSLLAEQ-------PSTS---TGIMAMYT 1843 ILD PVGV GE+ ++ + P L+ E+ P TG + + Sbjct: 3328 ILDDHFRLQPVGVAGELCISSIGLARGYHNRPELMDEKFVDNPFAPGERMYRTGDLVRWL 3387 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKILAYI 1903 + I+ +G + G I L ++ Q++ P + +D ++AY Sbjct: 3388 PNGTIEYLGRIDHQVKIRGYRIELGEVEAQMLRVPSVQEVVAMAVEGDDGYKD--LVAYF 3445 Query: 1904 TPRGTSIPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKALRE 1963 +V E++ L +PG IPS F+ L+++PL S G I+ + L A Sbjct: 3446 V--AAQKLEVSELRAVLSEMLPGYMIPSRFIQLEDMPLTSNGKIDRKALKGERGWAAASS 3503 Query: 1964 EIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDISLR 2023 E P E +LAEIW+ VL +E D+FF GG+SL+A+LL I+KE + +ISLR Sbjct: 3504 EA--PRTPVEIQLAEIWQEVLGVESAGVKDNFFHFGGHSLRAALLVSRIRKEMNREISLR 3561 Query: 2024 MLFEHPTVKGLAKAINGAGKSFLPEITPLGKKDWYPQSSSQKRLFAIEQMGGAGTAYNIT 2083 +FE PT++GLA+AI G EI G ++ YP SS+QKRLF + Q+ G +YN+ Sbjct: 3562 AVFESPTIEGLARAIEGYTPLNFEEIPTAGAREHYPLSSAQKRLFILSQLEGGELSYNMP 3621 Query: 2084 GILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFELLHDEPVQVIHDDIPFSISYSIAEDED 2143 GIL VEG LD R+E+AF+RL+ RH LRT F ++ EPVQ + D+PF++ Y+ +E+ Sbjct: 3622 GILTVEGALDRERLEQAFRRLIHRHGSLRTRFVTVNGEPVQQLLTDVPFTVEYAELSEEE 3681 Query: 2144 EPELVKRFILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGISANILCNDLISLYS 2203 +++F+ PF L APL RV ++ + H+++ DMHHI++DG+S NIL + + Y Sbjct: 3682 AGATLQQFVRPFDLGVAPLLRVGLIRIAHERHLLLFDMHHIVSDGVSMNILIEEFLRFYQ 3741 Query: 2204 GENL-PGLEVQYKDYTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQSF 2262 E++ P L++QY DY E L +ER++ Q YW +P L LP D RP V+SF Sbjct: 3742 EEDVFPELQIQYTDYAVWQQEQLESERLKAQEAYWLDAFRGSLPVLDLPGDEVRPAVRSF 3801 Query: 2263 DGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRFN 2322 G +DS L+ L+ L+ R +TL+ +LLA+Y LL KY+ QED+++GSPVAGR + Sbjct: 3802 AGDRIDFQIDSSLSASLQELATRTGSTLFMVLLAAYTALLHKYTGQEDVIVGSPVAGRSH 3861 Query: 2323 YSTNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIERD 2382 + ++GMFV T+A+R P K F+ +L EVKE L A+ENQDYPFEEL+ KL ++RD Sbjct: 3862 ATLEGLIGMFVGTVALRTYPEGEKPFEAYLQEVKETALRAYENQDYPFEELVEKLELQRD 3921 Query: 2383 ISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYEFKNDVAKFDLILEVIENTENLTLNFE 2442 +SRNP+FD MFVLQ+++ + ++ +R Y+ + AKFDL L V E L E Sbjct: 3922 LSRNPLFDTMFVLQNIEQG--EQEIEGLRFTPYDNVHPAAKFDLTLTVSEADGALNCTLE 3979 Query: 2443 YCAKLFQESTIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYPG 2502 Y ++++ T RM+ F++++ + N + LS +D++ +E RL+ ++ YP Sbjct: 3980 YATAIYKQETAERMAGHFVQLIREAIANPGMPLSSLDIVTPQEKSRLMEAPDEAKADYPR 4039 Query: 2503 GKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILME 2562 KT++ LFEEQAARTP AVA+V + +++Y N + N +AR LR +G++PD GI+ + Sbjct: 4040 DKTIHALFEEQAARTPNAVAVVCEDAALSYSELNERANGLARTLRERGLQPDGLAGIMAD 4099 Query: 2563 HSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEFI 2622 S E+++ + A++KAGGAYVP+DP YP +RI F+++DS +++LT L ++ F G+ + Sbjct: 4100 RSLEMVVGILAILKAGGAYVPVDPEYPEDRIRFMLEDSGAKLLLTQAHLEQRVSFAGDIV 4159 Query: 2623 DAASSKWYCGDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYVH 2682 + Y D SN P+ LAY+IYTSG+TG PKG + H+ + ++ + Sbjct: 4160 SLDKTASYKEDVSNLQPAAGPEHLAYVIYTSGTTGKPKGTLIEHKNVVRLLFNDKNMFDF 4219 Query: 2683 GEAVDFPLYSSIAFDLSVTLIYIPLISGNKVFIYSGVSYES--LLEAVVIDNQVDFIMLT 2740 G + L+ S FD SV +Y L++G ++ I ++ +S ++ D +V + T Sbjct: 4220 GPQDTWTLFHSFCFDFSVWEMYGALLNGGRLVIVPSLTAKSPDRFLQLLKDQKVTVLNQT 4279 Query: 2741 PSHLKILGEYDL----SRLKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETTV 2796 P++ L + +L + L +R I GGEA P K + ++ + V++ N+YG TETTV Sbjct: 4280 PTYFYQLLQEELGHQAAELSLRMIIFGGEALAPALLKDWRTKYPQ-VQLINMYGITETTV 4338 Query: 2797 ACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYLNR 2856 T+ + + IG I ++ Y++D+ + Q IGIPGEL +AG G++RGYLNR Sbjct: 4339 HVTYKEITELEIEQGRSNIGTTIPTLRAYILDEQRRPQPIGIPGELYVAGVGLARGYLNR 4398 Query: 2857 EELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIENQL 2916 ELT EKFV PF+ MYR+GDL R L DG++E+LGR+D QVKIRG+RIELGE+E +L Sbjct: 4399 PELTEEKFVAHPFEAGERMYRSGDLARWLPDGSMEYLGRIDHQVKIRGYRIELGEVEAKL 4458 Query: 2917 VKQPGVNKAAVIISTGPTDSRYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFFVQMKS 2976 + P V +A V+ + + L Y+TAD + P +M+PS+F+Q++ Sbjct: 4459 LHAPAVREAVVLAREDGSGQKVLVGYFTADQMLTVGELRKALAAELPTYMIPSYFMQLEQ 4518 Query: 2977 IPLTASGKVDRKKLPDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSFIKL 3036 +PLT +GK+DRK LP + Q Y P+ EE LA VW+ VLG +VG + F L Sbjct: 4519 MPLTPNGKLDRKALPAPETNVQTGAVYEPPRTKAEEALASVWQGVLGAQQVGIHDHFFDL 4578 Query: 3037 GGDSIKAIQIVSRLKKYGLSLEVKELFLHQNIKGISPFVKQNIKRHNQGTIEGPVKLTAI 3096 GGDSIKAIQ+ SRL + G LE+K+LF + I +SP+++ + QG I+G +L I Sbjct: 4579 GGDSIKAIQVSSRLFQAGYKLEMKDLFKYPTIAELSPYLQAAGRTAEQGEIKGAAELMPI 4638 Query: 3097 QKWFFEQNFAEMHHWNQSILLH-NERFDVQFIRQAFQRITEHHDALRMVYRHTGQAGVEQ 3155 Q+WFFE++ AE HH+N +++L+ + FD +R +I HHDALRMV+R T +AG Sbjct: 4639 QRWFFERHTAEPHHYNHAVMLYRKDGFDEAALRLTMDQIAIHHDALRMVFRPT-EAGYAA 4697 Query: 3156 SNRGL-AGELFSLEVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDYL 3214 NRG GEL++L++ D+ +D T + A IQ DLE GPL KLGL+ +GD+L Sbjct: 4698 WNRGTDEGELYTLDIADMRQAEDQTAAVQAQADAIQASFDLEGGPLFKLGLFHCDDGDHL 4757 Query: 3215 AIVIHHLVVDGVSWRIILDDFASCYLSLDNGEEAGLIEKSDSYQKWAEALEVYANSPKLL 3274 IVIHHL+VDGVSWRI+ +D A+ Y NG+ L +K+DSY W+E YA P L Sbjct: 4758 LIVIHHLLVDGVSWRILFEDIAAGYEQALNGQAIVLPQKTDSYLVWSEQATKYAAGPALD 4817 Query: 3275 QELAYWTDVNRIAVPALPKDSEAGNGKIKDRYQTKTVLSEKETTNLLRHAGDAYQTETXX 3334 +E AYW + + LPKD + G I+D S +ET LLR A AY TET Sbjct: 4818 KERAYWQLIEEAILAPLPKDEDQKPGTIRDTESVTVTWSAQETDLLLRQANRAYHTETND 4877 Query: 3335 XXXXXXXXXIKGWANVDRVRINMEGHGREALIQDLDITRTVGWFTSTYPLVLELANSHEL 3394 I+ W ++++ +N+EGHGRE ++ DLDITRTVGWFT+ YP++L L E+ Sbjct: 4878 LLLTALGAAIQRWTGMEQILVNLEGHGREMIVPDLDITRTVGWFTTQYPVLLNLQGGQEV 4937 Query: 3395 PLHIMTTKETIRQTPNKGMGYQVLKYLTSPELRAAVDFNVMPEISFNYLGQF-----GNE 3449 I KE +R+ P+KG+GY +LKY+ +PE +V F V PEISFNYLGQF GN Sbjct: 4938 SARIKRIKENLREVPHKGIGYGLLKYM-APE--KSVGFGVEPEISFNYLGQFDQDLEGNA 4994 Query: 3450 ASYGTFEICNTFMESTESPESHRPYAIDINAMIVGNRVEIRVDYNPGQFNEATMSRFAEL 3509 S T + + T P+ YA+D+N MI ++ + + Y+ Q+ T+S FAEL Sbjct: 4995 LSLSTHSVGKALSDLT--PQQ---YALDVNGMIAEGQLSLTITYSSRQYRNETVSHFAEL 5049 Query: 3510 LLNSLKLIISHCTREERIQRSPSDLTYKKLTFEELDDL--NRLYPGGITDVYTMTPMQES 3567 L +SL +I HC +ER Q +PSD+ ++ LT E+LD L + G I DVY +TPMQ+ Sbjct: 5050 LQSSLSEVIRHCVAQERSQLTPSDVLFQGLTLEQLDRLTAQTAHIGEIEDVYKLTPMQKG 5109 Query: 3568 MLFHALKNKRSDAYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPLQI 3627 MLFH+L S +Y EQ +L+G ++ ESF+ +V ++ ILRT F PLQ+ Sbjct: 5110 MLFHSLLEPDSSSYFEQATFELRGSFDVDIFFESFQALVQRHAILRTGFYNNIADVPLQV 5169 Query: 3628 VLGSSDFHLEFEDITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVYQM 3687 V L + D+ E+ A ++ A D K F L + PLMR +L+ S + Sbjct: 5170 VFKQRLIPLHYVDLRDASMQEQEARIKAYIAEDMVKGFSLSEDPLMRVTVLQKDQSCL-V 5228 Query: 3688 LWSFHHILMDGWCIGIVLKDMLEHYKQLNAGSRPSLETHQ-YRLYLDWLASKNKEEAKVY 3746 LWSFHHI+MDGWCI I+ +++ ++Y +P L Q Y Y++WL +++ +EA Y Sbjct: 5229 LWSFHHIVMDGWCIPIITQELFDYYSAKKQQVQPVLPPAQPYSRYIEWLDAQDDQEASTY 5288 Query: 3747 WMQYLEDYKYKELLRKEGTSKEFRLAVLDIK-----LEEKVRTAVTHVASSSGITINSFF 3801 W QYLEDY +L + T + + A +K L + + VA + +T+N+ Sbjct: 5289 WSQYLEDYDGNTVLPEGKTKSQAKEAGYVLKEHVLHLGASLTGKMDVVAKRNHVTVNTLM 5348 Query: 3802 QAVWGILLSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRLS-GKTFHELA 3860 Q WG++L +Y+ + DVVFG V+SGR EI GIE MVGLFINT+P+RV+ S + F E+ Sbjct: 5349 QTAWGLILQRYNASSDVVFGGVVSGRPAEIAGIENMVGLFINTVPIRVQSSKDEAFVEVM 5408 Query: 3861 GEIQSSFISSEQYGYVPLSDIQAWS--HRDLINHVMVFENYPLDREIRDTDGQQMEYGFQ 3918 Q+ ++ Y PL +IQ + +DLI+H+M+FENYPLD ++ + G Q E + Sbjct: 5409 KRTQAQSLAGRAYDTYPLYEIQGKTTQKQDLISHIMIFENYPLDEQVEQS-GNQTEDNLE 5467 Query: 3919 IAGCEILEHTNYDFSIIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTACPQI 3978 +A + E TNYDF++++ PGED + I YNA Y++E+I+ + +LL ++ QV A PQ Sbjct: 5468 VANFTMFEQTNYDFNLVVIPGEDIKVCIRYNASVYEQESIARIGGHLLQMLDQVAARPQA 5527 Query: 3979 EAGDVEVLSQEEKLKLMN 3996 ++E+++ EE++ L++ Sbjct: 5528 TIQELEIVTSEERINLLD 5545 Score = 1555 bits (4026), Expect = 0.0, Method: Compositional matrix adjust. Identities = 854/2233 (38%), Positives = 1291/2233 (57%), Gaps = 55/2233 (2%) Query: 1801 ILDKDMHPSPVGVPGEVYLA-------RLTEPSLLAE----------QPSTSTGIMAMYT 1843 ILD+ PVGVPGE+Y+A L P L +E + TG +A + Sbjct: 787 ILDEQRRLQPVGVPGELYIAGDGLARGYLNRPDLTSEKFVEHPYRVGERLYRTGDLARWL 846 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKIL-AY 1902 D I+ +G + G I L ++ Q++ P + V + ++ QK+L AY Sbjct: 847 PDGNIEYLGRIDHQVKIRGYRIELGEVEAQILKAPSVRETIVLARED---EQGQKLLCAY 903 Query: 1903 ITPRGTSIPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKALR 1962 P E++ L + +P IPS F+ L+++PL G ++ R LPA + Sbjct: 904 YVASSDLSPG--ELRAQLAAELPAYMIPSYFVPLEQMPLTPNGKLDRRALPAPESSVQSG 961 Query: 1963 EEIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDISL 2022 E + P E ++ IW+++L + V D+FFE+GG+SL+A++L I KE ISL Sbjct: 962 EAYLAPRTAVEAQMVLIWQDILGVARVGVRDNFFEIGGHSLRATVLVSRIHKELGCSISL 1021 Query: 2023 RMLFEHPTVKGLAKAINGAGKSFLPEITPLGKKDWYPQSSSQKRLFAIEQMGGAGTAYNI 2082 R +F+ PTV+ LA+ + + I + + YP SS+QKRL+ + QM G +YN+ Sbjct: 1022 REVFQSPTVESLAQLVKKHIPTLYESIPQATESEAYPVSSAQKRLYVLRQMDGGELSYNM 1081 Query: 2083 TGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFELLHDEPVQVIHDDIPFSISYSIAEDE 2142 G+ V+G LD R+E AFQ L++RHE LRT F + E VQ +H ++ F+++Y+ A E Sbjct: 1082 PGVFTVDGLLDRTRLESAFQALIQRHESLRTGFYMQDGELVQRVHRNVSFALNYTEALVE 1141 Query: 2143 DEPELVKRFILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGISANILCNDLISLY 2202 + L+ FI F L+QAPL RV +V + H+++ DMHHII+DG+S IL +L LY Sbjct: 1142 ETDTLIHNFIRAFDLSQAPLLRVSLVKLQEERHLLLFDMHHIISDGVSIQILIEELTHLY 1201 Query: 2203 SGENLPGLEVQYKDYTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQSF 2262 GE LP L +QYKDY E N+ + +YW Q ++P L LP DF RP V+SF Sbjct: 1202 QGEQLPELHIQYKDYAVWQREQSENQ-WQDLEKYWLQSFEGELPVLDLPTDFQRPSVRSF 1260 Query: 2263 DGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRFN 2322 +G+ TLD + ++ L++R TTLY +LLA+Y++LL KY+ QEDIV+GSPVAGR Sbjct: 1261 EGSRIDFTLDESGNKAIQELASRTGTTLYMVLLAAYSVLLHKYTGQEDIVVGSPVAGRPQ 1320 Query: 2323 YSTNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIERD 2382 ++GMFVNTLA+R+ PA KTFQ++LLE+KE L+AFE+QDYPFE+L+ KLG+ RD Sbjct: 1321 AELEGIIGMFVNTLALRSYPAGDKTFQDYLLEIKETALKAFEHQDYPFEKLVEKLGVGRD 1380 Query: 2383 ISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYEFKNDVAKFDLILEVIENTENLTLNFE 2442 +SRNP+FD + VLQ+ + D +D + Y AKFDL L V E L E Sbjct: 1381 VSRNPLFDTLLVLQNTEQEEQD--MDGVHFTPYLMDTVTAKFDLSLNVEEKGSKLAFGLE 1438 Query: 2443 YCAKLFQESTIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYPG 2502 Y L++ ++ R++ LRIL V N + L++I+++ EE +++ FN T+ YP Sbjct: 1439 YSTALYRRESVERLATHLLRILHAVAANPQLQLAEIEMITPEEKVQIVEVFNATSAPYPR 1498 Query: 2503 GKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILME 2562 KT+++LF EQ RTP ALV +TY K +++A+ LR G + V ++ Sbjct: 1499 DKTIHELFAEQVKRTPEQTALVFGDVQLTYLELEDKASRLAQTLRRLGTLREQPVAVMGG 1558 Query: 2563 HSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEFI 2622 S E++I M AV++AGGAYVPIDP YP +R+ +++ DS+ +++L KG + + Sbjct: 1559 RSIEMVIGMLAVLQAGGAYVPIDPDYPEDRVRYMLNDSDAKLLLVQKGELISVDYGIPIV 1618 Query: 2623 DAASSKWYCGDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYVH 2682 D +S + Y + + P + LAY+IYTSG+TG PKGVM H+ + V + YV Sbjct: 1619 DLSSEEAYAAEPAQPETAQGSQGLAYVIYTSGTTGRPKGVMVEHRNVVRLV--KETNYVE 1676 Query: 2683 -GEAVDFPLYSSIAFDLSVTLIYIPLISGNKVFIYSG--VSYESLLEAVVIDNQVDFIML 2739 E+ ++AFD S I+ L++G +++ + L+A + + + L Sbjct: 1677 LNESTRILQTGAVAFDASTFEIWGALLNGGQLYFVENDDILIADRLKAAITKYGITTMWL 1736 Query: 2740 TP---SHLKILGEYDLSRLKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETTV 2796 T + L + EY LK ++GG+ + + + V + N YGPTE T Sbjct: 1737 TSPLFNQLSLQDEYLFRGLK--ALLVGGDVLSLSHMNRVIEANPDLVPI-NCYGPTENTT 1793 Query: 2797 ACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYLNR 2856 T Y+ P + VPIG PI N YVV+ + +LQ IG GEL + G+GV+RGYLNR Sbjct: 1794 FSTTYK-IPGR-AEGGVPIGRPIRNSTAYVVNGSLQLQPIGAWGELIVGGEGVARGYLNR 1851 Query: 2857 EELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIENQL 2916 +LT EKFVP P + YRTGDLVR L DGN+EF GR+D+QVKIRG+RIEL EIE QL Sbjct: 1852 PDLTAEKFVPSPVKDGEPCYRTGDLVRWLPDGNLEFKGRIDEQVKIRGYRIELPEIEAQL 1911 Query: 2917 VKQPGVNKAAVIISTGPTDSRYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFFVQMKS 2976 K V A V++ + LCAYY AD + P +M+PS+F+QM Sbjct: 1912 AKVESVIDAVVVVRADELGEKQLCAYYVADRTLTAGEVRLSLSQVLPGYMIPSYFIQMDR 1971 Query: 2977 IPLTASGKVDRKKLPDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSFIKL 3036 +PLT++GKVDR+ LP Y+AP+ EE LA VW+ VLG +VG ++F +L Sbjct: 1972 MPLTSNGKVDRRSLPAPQVGAHTGRKYTAPRTPAEEALASVWQGVLGAKQVGIHDNFFEL 2031 Query: 3037 GGDSIKAIQIVSRLKKYGLSLEVKELFLHQNIKGISPFVKQNIKRHNQGTIEGPVKLTAI 3096 GGDSIKAIQ+ SRL + G LE+K+LF I + ++ + QG + G +LT + Sbjct: 2032 GGDSIKAIQVSSRLLQAGYRLEMKQLFKSPTIAELGAEIQTAVHMAEQGVVRGTTRLTPV 2091 Query: 3097 QKWFFEQNFAEMHHWNQSILLHNER-FDVQFIRQAFQRITEHHDALRMVYRHTGQAGVEQ 3155 Q+WFF + AE HH+NQ+++L+ E+ F+ + + Q +++ EHHDALRMV+R T + G E Sbjct: 2092 QQWFFGRKQAEPHHFNQAVMLYREQGFEEKALHQVLRKLAEHHDALRMVFRQT-EHGYEA 2150 Query: 3156 SNRGL-AGELFSLEVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDYL 3214 NR L GEL+SL DL D T + + IQ+ I+L +GPLLKLGL+ +GD+L Sbjct: 2151 WNRDLDEGELYSLFTADLRNESDPTAAITSLSDDIQRSINLAEGPLLKLGLFHCQDGDHL 2210 Query: 3215 AIVIHHLVVDGVSWRIILDDFASCYLSLDNGEEAGLIEKSDSYQKWAEALEVYANSPKLL 3274 IVIHHLVVDGVSWRI+ +D A+ Y + G+ +K+DS++ W +AL Y+ P + Sbjct: 2211 LIVIHHLVVDGVSWRILFEDIAAGYEQVIQGQALTFPQKTDSFRDWGDALARYSEGPDME 2270 Query: 3275 QELAYWTDVNRIAVPALPKDSEAGNGKIKDRYQTKTVLSEKETTNLLRHAGDAYQTETXX 3334 AYW ++ + LPKD + ++D + +ET LLR A AYQTET Sbjct: 2271 THRAYWRELEDQPLEQLPKDEAVESLLLQDSKVITAQWTLEETDQLLRKAHRAYQTETND 2330 Query: 3335 XXXXXXXXXIKGWANVDRVRINMEGHGREALIQDLDITRTVGWFTSTYPLVLELANSHEL 3394 + W+ + +V +N+EGHGRE +I ++DITRTVGWFTS +P++L+L + E+ Sbjct: 2331 LLLTALGMAVSKWSGIGKVAVNLEGHGREPIIPNIDITRTVGWFTSQFPVILDLGDDPEV 2390 Query: 3395 PLHIMTTKETIRQTPNKGMGYQVLKYLTSPELRAAVDFNVMPEISFNYLGQFGNEASYGT 3454 I + KE +R+ PNKG+GY +LK + S + F++ PEISFNYLGQF + + Sbjct: 2391 ASLIKSVKEGLRRIPNKGIGYGLLKTMASQLDEDS--FSLQPEISFNYLGQFDQDLQGSS 2448 Query: 3455 FEICNTFMESTESPESHRPYAIDINAMIVGNRVEIRVDYNPGQFNEATMSRFAELLLNSL 3514 +I S +S Y +DIN M+ + + + YN Q+ +TM + A + SL Sbjct: 2449 LQISPYPTGSAQSLLEEPAYTLDINGMVTDGALTLTITYNGKQYKSSTMEQLAGYIEESL 2508 Query: 3515 KLIISHCTREERIQRSPSDLTYKKLTFEELDDLNRL--YPGGITDVYTMTPMQESMLFHA 3572 + ++ HC +E+ +PSD+ K L+ +L++L++ + G I +VY++TPMQ+ MLFH Sbjct: 2509 RELLQHCVNQEKTILTPSDVLAKGLSIADLEELSKQTSHIGDIENVYSLTPMQKGMLFHD 2568 Query: 3573 LKNKRSDAYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPLQIVLGSS 3632 + + AY EQ D KG S +V ++ ILRT F PLQ+V Sbjct: 2569 MFEPHTGAYFEQAAFDFKGSFDPTAFGHSLDAVVERHAILRTNFYSGWGSEPLQVVFRHR 2628 Query: 3633 DFHLEFEDITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVYQMLWSFH 3692 L +ED+ M +S++ A+++ A D+ F+L + L+R +L+T + +++LWSFH Sbjct: 2629 GAKLVYEDLREMNASQREAYLKTFGAKDKALGFNLAEDELLRVSILQTDEESFRLLWSFH 2688 Query: 3693 HILMDGWCIGIVLKDMLEHYKQLNAGSRPSL-ETHQYRLYLDWLASKNKEEAKVYWMQYL 3751 HI+MDGWC+ ++ +++ EHY L G P L E H Y Y++WL +++ A YW +YL Sbjct: 2689 HIVMDGWCVPLITQEVFEHYFALLEGREPQLAEVHPYSRYIEWLEQQDEAAASNYWSRYL 2748 Query: 3752 EDYKYKELLRKEGTSKE---FRLAVLDIKLEEKVRTAVTHVASSSGITINSFFQAVWGIL 3808 Y+ + LL + G + + + L+ L ++ + VA + +T+N Q++WGI Sbjct: 2749 AGYEQQTLLPQVGGASKGEGYVAEKLNYPLSRELTERLEKVARDAHVTMNILLQSLWGIA 2808 Query: 3809 LSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRLSGKT-FHELAGEIQSSF 3867 L +Y+ ++DVV+G+V+SGR EI GI+RM+GLFINTIPVRV+ F L + Q + Sbjct: 2809 LQRYNGSKDVVYGSVVSGRPAEIPGIDRMIGLFINTIPVRVKTEENLPFTVLMKQQQEQY 2868 Query: 3868 ISSEQYGYVPLSDIQAWS--HRDLINHVMVFENYPLDREIRDTDGQQMEYGFQIAGCEIL 3925 ++S Y PL +IQA + +DLI+H+MVFENYP++ E+ G + F+I E+L Sbjct: 2869 MASHMYDTYPLFEIQAQTDQKQDLISHIMVFENYPVEEEVERLGGGEAA--FEIEEAELL 2926 Query: 3926 EHTNYDFSIIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTACPQIEAGDVEV 3985 E TNYDF++I+ PGE+ + YNAL YD TI ++ +L+ ++ Q+ P I +E+ Sbjct: 2927 EQTNYDFNLIVLPGEEMRLLFQYNALVYDPVTIEQIKGHLVHLMEQIVENPAISVDALEL 2986 Query: 3986 LSQEEKLKLMNVF 3998 ++ +E+ +++NV+ Sbjct: 2987 VTPQEREQILNVW 2999 Score = 1263 bits (3269), Expect = 0.0, Method: Compositional matrix adjust. Identities = 713/2046 (34%), Positives = 1135/2046 (55%), Gaps = 64/2046 (3%) Query: 1991 TNDDFFELGGNSLKASLLAFSIQKEFSTDISLRMLFEHPTVKGLAKAINGAGKSFLPEIT 2050 T F EL +SL + ++ + +E S +LF+ T++ L + A + + EI Sbjct: 5042 TVSHFAELLQSSL-SEVIRHCVAQERSQLTPSDVLFQGLTLEQLDRLT--AQTAHIGEI- 5097 Query: 2051 PLGKKDWYPQSSSQKRLFAIEQMGGAGTAYNITGILHVEGKLDPGRMEEAFQRLVKRHEP 2110 +D Y + QK + + ++Y + G D E+FQ LV+RH Sbjct: 5098 ----EDVYKLTPMQKGMLFHSLLEPDSSSYFEQATFELRGSFDVDIFFESFQALVQRHAI 5153 Query: 2111 LRTSF-ELLHDEPVQVIHDDIPFSISYSIAED---EDEPELVKRFILP-----FSLNQAP 2161 LRT F + D P+QV+ + Y D +++ +K +I FSL++ P Sbjct: 5154 LRTGFYNNIADVPLQVVFKQRLIPLHYVDLRDASMQEQEARIKAYIAEDMVKGFSLSEDP 5213 Query: 2162 LFRVHIVSRSDHEHIVIMDMHHIIADGISANILCNDLISLYSGEN------LPGLEVQYK 2215 L RV ++ + D +V+ HHI+ DG I+ +L YS + LP + Y Sbjct: 5214 LMRVTVLQK-DQSCLVLWSFHHIVMDGWCIPIITQELFDYYSAKKQQVQPVLPPAQ-PYS 5271 Query: 2216 DYTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQSFDGAC--YSVTLDS 2273 Y E L + ++ YW Q L D + LP + + + + L + Sbjct: 5272 RYI----EWLDAQDDQEASTYWSQYLEDYDGNTVLPEGKTKSQAKEAGYVLKEHVLHLGA 5327 Query: 2274 DLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRFN--YSTNNMVGM 2331 LT + V++ R T+ TL+ ++ ++L +Y+ D+V G V+GR NMVG+ Sbjct: 5328 SLTGKMDVVAKRNHVTVNTLMQTAWGLILQRYNASSDVVFGGVVSGRPAEIAGIENMVGL 5387 Query: 2332 FVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIERD-ISRNPVFD 2390 F+NT+ +R Q +K + F E + + +L YP E+ K ++D IS +F+ Sbjct: 5388 FINTVPIRVQSSKDEAFVEVMKRTQAQSLAGRAYDTYPLYEIQGKTTQKQDLISHIMIFE 5447 Query: 2391 VMFVLQSLDLAVPDVHLDDIRLNGYEFKNDVAKFDLILEVIENTENLTLNFEYCAKLFQE 2450 + + ++ + D++ + + +D L VI E++ + Y A ++++ Sbjct: 5448 NYPLDEQVEQSGNQTE-DNLEVANFTMFEQT-NYDFNLVVIPG-EDIKVCIRYNASVYEQ 5504 Query: 2451 STIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYPGGKTVYQLF 2510 +I R+ L++L V + +++++ EE L+ + A YP + ++ LF Sbjct: 5505 ESIARIGGHLLQMLDQVAARPQATIQELEIVTSEERINLL-DWGGKAHTYPSDQGLHTLF 5563 Query: 2511 EEQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILMEHSFELIIS 2570 EEQ RTP +A V+ ITY N + N++A L +G++ + VG+L + S EL+++ Sbjct: 5564 EEQVVRTPDKIAAVNGDTQITYRELNEQANRLASTLIDQGLQSEQVVGLLADRSVELLVA 5623 Query: 2571 MFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEFIDAASSKWY 2630 + V+KAGGAYVPIDP YP ERI +I+KDS EI+LT L E F+G ++ S Y Sbjct: 5624 IMGVLKAGGAYVPIDPEYPQERIQYILKDSGAEILLTQSHLTELASFEGTVMELDSPHIY 5683 Query: 2631 CGDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYVHGEAVDFPL 2690 + NP +DL Y+IYTSG+TG PKG M H+G+ NY+WW +K Y G+ DFPL Sbjct: 5684 GTEVDNPNIPVGGNDLVYLIYTSGTTGNPKGTMINHKGIVNYIWWANKVYCAGKPTDFPL 5743 Query: 2691 YSSIAFDLSVTLIYIPLISGNKVFIYSGVSYESLLEAVVIDNQVDFIMLTPSHLKILGEY 2750 YSSI+FDL++T ++ PLI+G V IY G+ +++ ++ +N VD + LTP+HL ++ + Sbjct: 5744 YSSISFDLTMTSMFTPLINGGIVRIYDGIDKAEVVQHILRENAVDILKLTPTHLSLIKDM 5803 Query: 2751 DL-SRLKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDL 2809 + + +I++ I+GGE +K ++++YN YGPTET V C + Y P KD Sbjct: 5804 TIPAESRIQQLIVGGENLTTHLSKTITDLFGGNIKIYNEYGPTETVVGCMIHLYNPAKDT 5863 Query: 2810 RNPVPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPF 2869 R VPIG P N+ ++++D+ +L +G+ GE+ IAGDGV+RGYLNR ELT +KF+ +PF Sbjct: 5864 RESVPIGLPADNIYIHILDEQLRLVPLGVEGEMYIAGDGVARGYLNRPELTADKFIRNPF 5923 Query: 2870 QTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVII 2929 + G MYRTGDL R L +G++E++GR+D QVKIRG+RIELGEIE +L+ P V +A V+ Sbjct: 5924 ASEGNMYRTGDLARRLPNGDIEYIGRIDHQVKIRGYRIELGEIEAKLLDIPLVEEALVVA 5983 Query: 2930 STGPTDSRYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFFVQMKSIPLTASGKVDRKK 2989 + LCAY+ A+ M+ P +M+PS+FVQ+ +PLT +GK+DRK Sbjct: 5984 WADAHGQKSLCAYFVANREMSVSELRDELSAGLPAYMIPSYFVQLDVMPLTPNGKLDRKA 6043 Query: 2990 LPDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIVSR 3049 LP+ + ++AP+ +E LA +W+ VLG+ VG ++F +LGGDSIK+IQ+ SR Sbjct: 6044 LPEPNSGIKAGADFTAPRTDVENILASIWQGVLGVPLVGIHDNFFELGGDSIKSIQVSSR 6103 Query: 3050 LKKYGLSLEVKELFLHQNIKGISPFVKQNIKRHNQGTIEGPVKLTAIQKWFFEQNFAEMH 3109 L + G +E+K+LF + I ++ V + +Q + G V+L Q FF++ ++H Sbjct: 6104 LLQAGYKIEMKDLFGYPTIAELAQRVSVVSRIADQSEVHGAVRLGPAQHRFFDEQSMDLH 6163 Query: 3110 HWNQSILLH-NERFDVQFIRQAFQRITEHHDALRMVYRHTGQAGVEQSNRGLA-GELFSL 3167 H+NQS++L+ + F+ + + ++I EHHDALR+V+R G+ G+E NR + GEL+SL Sbjct: 6164 HFNQSVMLYRRDGFNTDALAEVVRKIAEHHDALRLVFRQ-GEQGLEAWNRSMGEGELYSL 6222 Query: 3168 EVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDYLAIVIHHLVVDGVS 3227 ++ DL D + AG + IQ+ I LE GPL +LGL++ G++L IVIHHL VDGVS Sbjct: 6223 QIHDLRDETDPASAIEAGAEAIQRSISLEDGPLFRLGLFRCAEGEHLLIVIHHLAVDGVS 6282 Query: 3228 WRIILDDFASCYLSLDNGEEAGLIEKSDSYQKWAEALEVYANSPKLLQELAYWTDVNRIA 3287 WRI+ +D Y GE L +K+DSY+ W E + +ANS QE YW +V Sbjct: 6283 WRILFEDLQDGYEQAARGEAVKLPQKTDSYRAWVEGITQFANSLAAEQERGYWAEVEGDG 6342 Query: 3288 VPALPKDSEAGNGKIKDRYQTKTVLSEKETTNLLRHAGDAYQTETXXXXXXXXXXXIKGW 3347 LPKD IKD S +ET L+ A Y TE + W Sbjct: 6343 FVPLPKDKVDSALLIKDSEAVTVRWSPEETEQFLKEANRTYNTEVNDLLLTALGMAVHEW 6402 Query: 3348 ANVDRVRINMEGHGREALIQDLDITRTVGWFTSTYPLVLELANSHELPLHIMTTKETIRQ 3407 ++RV I +EGHGRE ++ +LDITRT+GWFTS YP+ LE+ E+ I KE +R+ Sbjct: 6403 TGIERVGILLEGHGREPVVPELDITRTIGWFTSQYPVALEMGGELEIGARIKHVKEGLRR 6462 Query: 3408 TPNKGMGYQVLKYLTSPELRAAVDFNVMPEISFNYLGQFGNEASYGTFEICNTFMESTES 3467 PNKG+GY +LKYL+ F+ PEI+FNYLGQF + + G E+ + S Sbjct: 6463 IPNKGVGYGILKYLSDGS--DVSSFSAEPEITFNYLGQFDQDLAGGMMEVSPYSVGPEVS 6520 Query: 3468 PESHRPYAIDINAMIVGNRVEIRVDYNPGQFNEATMSRFAELLLNSLKLIISHCTREERI 3527 + + A++IN +I ++++ V YN Q + ++++F +L N L +I HC +ER Sbjct: 6521 EQMVQHQALNINGLIAEGQLQLSVSYNRHQLDGESVTKFVGILKNRLSEVIGHCVSKERT 6580 Query: 3528 QRSPSDLTYKKLTFEELDDLNR--LYPGGITDVYTMTPMQESMLFHALKNKRSDAYHEQC 3585 + +PSD+ K ++ E+++++ + G I ++Y +TPMQ+ MLFH+L S+ Y EQ Sbjct: 6581 ELTPSDVLLKDISLEKIEEIEEQTRHIGSIENMYKLTPMQKGMLFHSLLEPHSEVYFEQA 6640 Query: 3586 ILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPLQIVLGSSDFHLEFEDITHME 3645 +++G E S K ++ ++ ILRT F P+QIV +ED+ +E Sbjct: 6641 KFEIQGAFYPEDFKRSLKYLMKRHAILRTNFHAGWGDFPIQIVFKERACDFAYEDLHELE 6700 Query: 3646 SSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVYQMLWSFHHILMDGWCIGIVL 3705 + E A + A D+ + F+L + L+R +L+T + Y +LWS HHI++DGWC+ +VL Sbjct: 6701 ADEIQARLAAYTAQDKARGFNLAEEALLRVAILRTAEEAYHLLWSSHHIILDGWCMPLVL 6760 Query: 3706 KDMLEHYKQLNAGSRPSLETH-QYRLYLDWLASKNKEEAKVYWMQYLEDYKYKELL---- 3760 +++ E Y L P L Y Y+ WL + +EEA YW YLE Y+ + L Sbjct: 6761 QEVFETYGVLREQREPELPAAVSYSQYIQWLEKQGEEEASSYWRGYLEGYEQQTKLPQAI 6820 Query: 3761 -----RKEGTSKEFRLAVLDIKLEEKVRTAVTHVASSSGITINSFFQAVWGILLSKYDNA 3815 + E E + LD +L +++ VA +T+N+ QA WGI+L +Y+ + Sbjct: 6821 TQPSAKAEAYVSEKLVFTLDAELTDRLE----QVAKQHQVTMNTLMQAAWGIVLQRYNRS 6876 Query: 3816 EDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRLSGK-TFHELAGEIQSSFISSEQYG 3874 +D+VFG+V+SGR EI GIE M+GLFINT+PVRV+ G +F + Q +++ Y Sbjct: 6877 QDIVFGSVVSGRPAEIPGIESMIGLFINTVPVRVQAEGSDSFSHVMKRQQELYLAGHAYD 6936 Query: 3875 YVPLSDIQAWSH--RDLINHVMVFENYPLDREIRDTDGQQMEYGFQIAGCEILEHTNYDF 3932 PL +IQA S +DLI+H+MVFENYP++ + + + E ++I ++ E TNYDF Sbjct: 6937 SYPLYEIQAQSEQKQDLISHIMVFENYPVEEHLEEKIASE-EAEYRITDVQMFEQTNYDF 6995 Query: 3933 SIIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTACPQIEAGDVEVLSQEEKL 3992 ++I+ PG + YNA YD+E++ ++ +L I+ V P I ++E+++ EEK Sbjct: 6996 NLIVLPGRNLEFLYRYNARVYDRESVERIQGHLTRILTSVAVQPTIRIDELELITPEEKS 7055 Query: 3993 KLMNVF 3998 +++ V+ Sbjct: 7056 QIIEVW 7061 Score = 620 bits (1599), Expect = e-175, Method: Compositional matrix adjust. Identities = 390/1216 (32%), Positives = 645/1216 (53%), Gaps = 55/1216 (4%) Query: 2058 YPQSSSQKRLFAIEQMGGAGTAYNITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFEL 2117 Y +++QKR++ E + + ++G ++G ++ ++ ++K+++ R Sbjct: 7 YDLTNAQKRIWYTELLYPDTSVSQLSGTAKMKGHINIAAFMQSINLIIKQYDAFRIRITS 66 Query: 2118 LHDEPVQVIHDDIPF----------SISYSIAEDEDEPELVKRFILPFSLNQAPLFRVHI 2167 + P Q + +P+ S S++E E E KR LP L + LF+ I Sbjct: 67 VDGVPQQYV---VPYEERQLECLDLSHYESVSEVEALLEQHKRKPLP--LLDSELFQFLI 121 Query: 2168 VSRSDHEHIVIMDMHHIIADGISANILCNDLISLY-----SGENLPGLEVQYKDYTALHN 2222 V S+ E+ + + MHHII+DGIS + N L + Y E G + Y Y A N Sbjct: 122 VKISEEEYWINIKMHHIISDGISMVVYGNQLTAFYMELIQGNEPKLGDDCSYIQYIADEN 181 Query: 2223 EMLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQSFDGACYSVTLDSDLTRGLKVL 2282 ++R ++ YW SD +P LT + P S T+ L L+ Sbjct: 182 AYELSDRYQKDKAYWLDKFSD-LPELTGWKSY-NPLSLSTHAVREHFTVPEVLYHELQAF 239 Query: 2283 SNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRFNYSTNNMVGMFVNTLAMRNQP 2342 + + +L+ + + I + K +NQ D+VIG+ A R N +GMFV+T A R Sbjct: 240 CQQNRISLFQFFMGAMYIYIHKMTNQPDVVIGTSFANRGNKKEKQKIGMFVSTAAARTYV 299 Query: 2343 AKHKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIERDISRNPVFDVMFVLQSLDLAV 2402 K FL +V + + +Q YP+ +LI L R++ N +F + + Sbjct: 300 KKDIDVLSFLQDVARDQMSVLRHQKYPYNQLIQDL---REMHGNKDIQRLFGVSMEYRLI 356 Query: 2403 PDVHLDDIR-LNGYEFKNDVAKFDLILEVIE--NTENLTLNFEYCAKLFQESTIIRMSER 2459 V LDD+R L Y+F D D + ++E + L L+ +Y +LF+ S + M + Sbjct: 357 NWVDLDDVRILTDYDFCGDEVN-DFVFHIVEILDEGELVLDVDYRTELFERSEVKDMVSQ 415 Query: 2460 FLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYPGGKTVYQLFEEQAARTPG 2519 L I ++ + + ++++ LL + E ++ A YP KT++ LFEEQA RTP Sbjct: 416 LLTIAEQIIHSPQLSIAEVSLLGEPEEQSILALSEGAAVDYPREKTIHGLFEEQAERTPD 475 Query: 2520 AVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILMEHSFELIISMFAVMKAGG 2579 VA+ +SITY N + NQ+AR LRS+GV DT VGI+ + S E++I M A++KAGG Sbjct: 476 HVAVQMDEQSITYLALNEQANQLARYLRSEGVGADTLVGIMADRSLEMVIGMLAILKAGG 535 Query: 2580 AYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEFIDAASSKWYCGDDSNPVS 2639 AYVPIDP YP ERI+++++DS + ++LT L E F G+ + + Y GD SN S Sbjct: 536 AYVPIDPDYPEERIHYMLEDSGVSLLLTQSHLWESTTFDGKLVSLDEAATYTGDASNLES 595 Query: 2640 VNSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYVHGEAVDFPLYSSIAFDLS 2699 ++ P LAY+IYTSG+TG PKG + H+ + ++ + + L+ S FD S Sbjct: 596 ISGPSHLAYVIYTSGTTGKPKGTLIEHKNVVRLLFNDKNLFDFNSQDTWTLFHSFCFDFS 655 Query: 2700 VTLIYIPLISGNKVFIYSGVSYES---LLEAVVIDNQVDFIMLTPSHL-KILGE---YDL 2752 V +Y L+ G K+ I ++ +S LE ++ DNQV + TP++ ++L E + Sbjct: 656 VWEMYGALLYGGKLVIVPSLTAKSPAAFLE-LLKDNQVTILNQTPTYFYQVLQEELMHSS 714 Query: 2753 SRLKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDLRNP 2812 + L +RK I GGEA P + + + DV++ N+YG TETTV T+ + Sbjct: 715 TELGLRKIIFGGEALSPSLLRNWRVKYP-DVQLINMYGITETTVHVTYKEITEHEIEAGK 773 Query: 2813 VPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPFQTS 2872 IG I + Y++D+ +LQ +G+PGEL IAGDG++RGYLNR +LT EKFV P++ Sbjct: 774 SNIGRTIPTLSAYILDEQRRLQPVGVPGELYIAGDGLARGYLNRPDLTSEKFVEHPYRVG 833 Query: 2873 GMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVIISTG 2932 +YRTGDL R L DGN+E+LGR+D QVKIRG+RIELGE+E Q++K P V + V+ Sbjct: 834 ERLYRTGDLARWLPDGNIEYLGRIDHQVKIRGYRIELGEVEAQILKAPSVRETIVLARED 893 Query: 2933 PTDSRYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFFVQMKSIPLTASGKVDRKKLPD 2992 + LCAYY A ++ P +M+PS+FV ++ +PLT +GK+DR+ LP Sbjct: 894 EQGQKLLCAYYVASSDLSPGELRAQLAAELPAYMIPSYFVPLEQMPLTPNGKLDRRALPA 953 Query: 2993 SFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIVSRL-K 3051 S Q +AY AP+ +E ++ L+W+++LG+ +VG ++F ++GG S++A +VSR+ K Sbjct: 954 PESSVQSGEAYLAPRTAVEAQMVLIWQDILGVARVGVRDNFFEIGGHSLRATVLVSRIHK 1013 Query: 3052 KYGLSLEVKELFLHQNIKGISPFVKQNI----KRHNQGTIEGPVKLTAIQKWFF---EQN 3104 + G S+ ++E+F ++ ++ VK++I + Q T +++ QK + + + Sbjct: 1014 ELGCSISLREVFQSPTVESLAQLVKKHIPTLYESIPQATESEAYPVSSAQKRLYVLRQMD 1073 Query: 3105 FAEMHHWNQSILLHNERFDVQFIRQAFQRITEHHDALRMVYRHTGQAGVEQSNRGLAGEL 3164 E+ + + + D + AFQ + + H++LR + V++ +R ++ Sbjct: 1074 GGELSYNMPGVFTVDGLLDRTRLESAFQALIQRHESLRTGFYMQDGELVQRVHRNVS--- 1130 Query: 3165 FSLEVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDYLAIV-IHHLVV 3223 F+L T+ + TD + I + DL + PLL++ L + +L + +HH++ Sbjct: 1131 FALNYTE--ALVEETDTL---IHNFIRAFDLSQAPLLRVSLVKLQEERHLLLFDMHHIIS 1185 Query: 3224 DGVSWRIILDDFASCY 3239 DGVS +I++++ Y Sbjct: 1186 DGVSIQILIEELTHLY 1201 Score = 527 bits (1358), Expect = e-147, Method: Compositional matrix adjust. Identities = 322/1011 (31%), Positives = 534/1011 (52%), Gaps = 47/1011 (4%) Query: 2086 LHVEGKLDPGRMEEAFQRLVKRHEPLRTSFEL-LHDEPVQVIHDDIPFSISYSIAEDEDE 2144 ++G P + + + L+KRH LRT+F D P+Q++ + +Y + + Sbjct: 6642 FEIQGAFYPEDFKRSLKYLMKRHAILRTNFHAGWGDFPIQIVFKERACDFAYEDLHELEA 6701 Query: 2145 PELVKRFIL--------PFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGISANILCN 2196 E+ R F+L + L RV I+ ++ + ++ HHII DG ++ Sbjct: 6702 DEIQARLAAYTAQDKARGFNLAEEALLRVAILRTAEEAYHLLWSSHHIILDGWCMPLVLQ 6761 Query: 2197 DLISLYS------GENLPGLEVQYKDYTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTL 2250 ++ Y LP V Y Y + L + + YW+ L L Sbjct: 6762 EVFETYGVLREQREPELPA-AVSYSQYI----QWLEKQGEEEASSYWRGYLEGYEQQTKL 6816 Query: 2251 PLDFPRPPV--QSFDGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQ 2308 P +P +++ TLD++LT L+ ++ + + T+ TL+ A++ I+L +Y+ Sbjct: 6817 PQAITQPSAKAEAYVSEKLVFTLDAELTDRLEQVAKQHQVTMNTLMQAAWGIVLQRYNRS 6876 Query: 2309 EDIVIGSPVAGRFNY--STNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQ 2366 +DIV GS V+GR +M+G+F+NT+ +R Q +F + +E L Sbjct: 6877 QDIVFGSVVSGRPAEIPGIESMIGLFINTVPVRVQAEGSDSFSHVMKRQQELYLAGHAYD 6936 Query: 2367 DYPFEELISKLGIERD-ISRNPVFDVMFVLQSLDLAVP----DVHLDDIRLNGYEFKNDV 2421 YP E+ ++ ++D IS VF+ V + L+ + + + D+++ F+ Sbjct: 6937 SYPLYEIQAQSEQKQDLISHIMVFENYPVEEHLEEKIASEEAEYRITDVQM----FEQTN 6992 Query: 2422 AKFDLILEVIENTENLTLNFEYCAKLFQESTIIRMSERFLRILTTVVENCNVLLSDIDLL 2481 F+LI + NL + Y A+++ ++ R+ RILT+V + + +++L+ Sbjct: 6993 YDFNLI---VLPGRNLEFLYRYNARVYDRESVERIQGHLTRILTSVAVQPTIRIDELELI 7049 Query: 2482 PKEETDRLIYTFNDTATAYPGGKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQ 2541 EE ++I + DTA YP +T++ +FEE+AA TP AL++ +TY +++ N+ Sbjct: 7050 TPEEKSQIIEVWGDTAAPYPREQTLHGIFEEKAALTPDRTALIYGETELTYGELHQQANR 7109 Query: 2542 MARMLRSKGVKPDTTVGILMEHSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSN 2601 +AR LR++GV+PD VGI++E S E+II + A++KAGGAYVPIDP +P +RI +++DS Sbjct: 7110 LARTLRAQGVRPDQPVGIMVERSLEMIIGIHAILKAGGAYVPIDPEFPEDRIRHMLEDSG 7169 Query: 2602 LEIMLTHKGLAEKCQFQGEFIDAASSKWYCGDDSNPVSVNSPDDLAYIIYTSGSTGLPKG 2661 +++LT L ++ F G + + Y D SN + P+ LAYIIYTSGSTG PKG Sbjct: 7170 AKLLLTKNHLKDRFPFTGTILALDDPQMYHADSSNLEPIAGPEHLAYIIYTSGSTGKPKG 7229 Query: 2662 VMTRHQGLTNYVWWGDKTYVHGEAVDFPLYSSIAFDLSVTLIYIPLI-SGNKVFIYSGVS 2720 VM H+ + + + Y F L ++ FD SV ++ G V + GV Sbjct: 7230 VMIEHRSAVHTLSQLEAEYPMLAGDRFLLKTTFTFDFSVPELFCWFFGQGTLVILPQGVD 7289 Query: 2721 YE--SLLEAVVIDNQVDFIMLTPSHLKILGEY-----DLSRLKIRKFIIGGEAFDPFYAK 2773 + +LLEAV N++ + L PS L +L +Y L ++ GE + Sbjct: 7290 KDPMALLEAVDT-NRITHLNLVPSMLSVLVQYLKESGTQGFLTLKYLFACGETLPAKLVE 7348 Query: 2774 KFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVDQNGKL 2833 +++ +++ + N+YGPTE V T Y + VPIG P NVQ++++D ++ Sbjct: 7349 EYY-KVSPYAVLENIYGPTEAAVYATRYTTSLETAALTHVPIGKPYANVQVWMMDSASQV 7407 Query: 2834 QGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFL 2893 +G+PGELCIAG+GV+RGY N+ +LT EKF+P P++ +YRTGDL R L DGN+E+L Sbjct: 7408 SPVGVPGELCIAGEGVARGYFNQPDLTAEKFIPHPYKPGARIYRTGDLARWLPDGNIEYL 7467 Query: 2894 GRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVIISTGPTDSRYLCAYYTADFPMNXXX 2953 GR+D QVKIRG+RIELGE+E Q++K P V +A + T S LCAY+ A+ + Sbjct: 7468 GRIDHQVKIRGYRIELGEVEAQILKVPSVQEAVALALADSTGSTQLCAYFVAEEGLAAGV 7527 Query: 2954 XXXXXXXXXPRHMVPSFFVQMKSIPLTASGKVDRKKLPDSFESFQMEDAYSAPQNFIEEK 3013 P +M+P+ FVQ+ +PL +GK+DRK LP + Y P+ E + Sbjct: 7528 LREALASELPSYMIPTAFVQLAQMPLNPNGKLDRKALPAPEALLRSTAEYIPPRTQTEVE 7587 Query: 3014 LALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIVSRLKK-YGLSLEVKELF 3063 LA +W EVLG+ ++G + F +LGG S+K + ++ ++ G+ L ++ +F Sbjct: 7588 LAQIWTEVLGVQEIGVKDHFFELGGHSLKVLGLIQKISSGMGVQLPLQLVF 7638 Score = 509 bits (1311), Expect = e-141, Method: Compositional matrix adjust. Identities = 374/1252 (29%), Positives = 614/1252 (49%), Gaps = 79/1252 (6%) Query: 2079 AYNITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSF-ELLHDEPVQVIHDDIPFSISYS 2137 AY +G DP + +V+RH LRT+F EP+QV+ + Y Sbjct: 2576 AYFEQAAFDFKGSFDPTAFGHSLDAVVERHAILRTNFYSGWGSEPLQVVFRHRGAKLVYE 2635 Query: 2138 IAEDEDEPE---LVKRF-----ILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGI 2189 + + + +K F L F+L + L RV I+ + ++ HHI+ DG Sbjct: 2636 DLREMNASQREAYLKTFGAKDKALGFNLAEDELLRVSILQTDEESFRLLWSFHHIVMDGW 2695 Query: 2190 SANILCNDLISLYSGENLPGLEVQYKDYTALHNEMLSNERIRQQGE-----YWQQLLSDD 2244 ++ ++ Y L G E Q + +H E + QQ E YW + L+ Sbjct: 2696 CVPLITQEVFEHYFA-LLEGREPQLAE---VHPYSRYIEWLEQQDEAAASNYWSRYLAGY 2751 Query: 2245 IPSLTLPLDFPRPPVQSFDGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSK 2304 LP + + + L +LT L+ ++ T+ LL + + I L + Sbjct: 2752 EQQTLLPQVGGASKGEGYVAEKLNYPLSRELTERLEKVARDAHVTMNILLQSLWGIALQR 2811 Query: 2305 YSNQEDIVIGSPVAGRFNY--STNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEA 2362 Y+ +D+V GS V+GR + M+G+F+NT+ +R + ++ F + + +E + + Sbjct: 2812 YNGSKDVVYGSVVSGRPAEIPGIDRMIGLFINTIPVRVKTEENLPFTVLMKQQQEQYMAS 2871 Query: 2363 FENQDYPFEELISKLGIERD-ISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYEFKNDV 2421 YP E+ ++ ++D IS VF+ V + ++ RL G E ++ Sbjct: 2872 HMYDTYPLFEIQAQTDQKQDLISHIMVFENYPVEEEVE-----------RLGGGEAAFEI 2920 Query: 2422 AKFDLILE-------VIENTENLTLNFEYCAKLFQESTIIRMSERFLRILTTVVENCNVL 2474 + +L+ + ++ E + L F+Y A ++ TI ++ + ++ +VEN + Sbjct: 2921 EEAELLEQTNYDFNLIVLPGEEMRLLFQYNALVYDPVTIEQIKGHLVHLMEQIVENPAIS 2980 Query: 2475 LSDIDLLPKEETDRLIYTFNDTATAYPGGKTVYQLFEEQAARTPGAVALVHQGESITYEH 2534 + ++L+ +E ++++ + +T Y T + L EEQA RTP A A+ + ES+TY Sbjct: 2981 VDALELVTPQEREQILNVWGNTKGIYEHCNTFHGLLEEQAGRTPDATAIWFEDESLTYAE 3040 Query: 2535 FNRKTNQMARMLRSKGVKPDTTVGILMEHSFELIISMFAVMKAGGAYVPIDPTYPSERIN 2594 N K N +AR LR++G+K VG++ E S E+I+ ++ +MKAGGAYVPIDP YP ERI+ Sbjct: 3041 LNAKANGLARRLRTQGIKTGDLVGLIAERSLEMIVGIYGIMKAGGAYVPIDPEYPKERIS 3100 Query: 2595 FIIKDSNLEIMLTHKGLAEKCQFQGEFIDAASSKWYCGDDSNPVSVNSPDDLAYIIYTSG 2654 ++++DS +++LT L E + + S Y D SN PDDLAY+IYTSG Sbjct: 3101 YMLEDSGAKLILTQAHLLEHLGWTENVLLLDESSTYDADTSNLEDTAGPDDLAYVIYTSG 3160 Query: 2655 STGLPKGVMTRHQGLTNYVWWGDKTYVHGEAV---DFPLYSSIAFDLSVTLIYIPLISGN 2711 +TG PKGV+ H+GL N D H E ++S++FD SV+ I L G Sbjct: 3161 TTGQPKGVLVEHRGLPNL---SDVYGTHFEVTPQDRIVQFASLSFDASVSEILTALSHGG 3217 Query: 2712 KVFIYS--GVSYESLLEAVVIDNQVDFIMLTPSHLKILGEYDLSRL-KIRKFIIGGEAFD 2768 + I S + +L E + D + L P++ L D RL +R + G A Sbjct: 3218 VLCIPSTQDILDHALFEQFMNDKGITVATLPPAYAIHL---DPERLPTLRCLLTAGSA-- 3272 Query: 2769 PFYAKKFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVD 2828 + + + V N YGPTE +V T + ++ + V IG PI N +Y++D Sbjct: 3273 --ASVELIEEWRKHVRYSNGYGPTEDSVCTTIWSVPDSEEATDIVSIGRPIANHSVYILD 3330 Query: 2829 QNGKLQGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPFQTSGMMYRTGDLVRMLQDG 2888 + +LQ +G+ GELCI+ G++RGY NR EL EKFV +PF MYRTGDLVR L +G Sbjct: 3331 DHFRLQPVGVAGELCISSIGLARGYHNRPELMDEKFVDNPFAPGERMYRTGDLVRWLPNG 3390 Query: 2889 NVEFLGRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVIISTGPTDSRYLCAYYTADFP 2948 +E+LGR+D QVKIRG+RIELGE+E Q+++ P V + + G + L AY+ A Sbjct: 3391 TIEYLGRIDHQVKIRGYRIELGEVEAQMLRVPSVQEVVAMAVEGDDGYKDLVAYFVAAQK 3450 Query: 2949 MNXXXXXXXXXXXXPRHMVPSFFVQMKSIPLTASGKVDRKKLPDSFESFQMEDAYSAPQN 3008 + P +M+PS F+Q++ +PLT++GK+DRK L E + AP+ Sbjct: 3451 LEVSELRAVLSEMLPGYMIPSRFIQLEDMPLTSNGKIDRKALKG--ERGWAAASSEAPRT 3508 Query: 3009 FIEEKLALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIVSRLKK-YGLSLEVKELFLHQN 3067 +E +LA +W+EVLG+ G ++F GG S++A +VSR++K + ++ +F Sbjct: 3509 PVEIQLAEIWQEVLGVESAGVKDNFFHFGGHSLRAALLVSRIRKEMNREISLRAVFESPT 3568 Query: 3068 IKG----ISPFVKQNIKRHNQGTIEGPVKLTAIQKWFF---EQNFAEMHHWNQSILLHNE 3120 I+G I + N + L++ QK F + E+ + IL Sbjct: 3569 IEGLARAIEGYTPLNFEEIPTAGAREHYPLSSAQKRLFILSQLEGGELSYNMPGILTVEG 3628 Query: 3121 RFDVQFIRQAFQRITEHHDALRMVYRHTGQAGVEQSNRGLAGELFSLEVTDLTGCDDHTD 3180 D + + QAF+R+ H +LR + V+Q L F++E +L+ + Sbjct: 3629 ALDRERLEQAFRRLIHRHGSLRTRFVTVNGEPVQQL---LTDVPFTVEYAELS-----EE 3680 Query: 3181 LMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDYLAIV-IHHLVVDGVSWRIILDDFASCY 3239 A ++ + DL PLL++GL + + +L + +HH+V DGVS I++++F Y Sbjct: 3681 EAGATLQQFVRPFDLGVAPLLRVGLIRIAHERHLLLFDMHHIVSDGVSMNILIEEFLRFY 3740 Query: 3240 LSLDNGEEAGLIEKSDSYQKWAEALEVYANSPKLLQELAYWTDVNRIAVPAL 3291 EE E Y +A + S +L + AYW D R ++P L Sbjct: 3741 -----QEEDVFPELQIQYTDYAVWQQEQLESERLKAQEAYWLDAFRGSLPVL 3787 Score = 149 bits (377), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 117/452 (25%), Positives = 210/452 (46%), Gaps = 42/452 (9%) Query: 1310 GYQP---KPLPSGPARESLTRAPQVLKLTEEQQQISLVIHSNDTHGVVHHETVG-LYLRG 1365 GY P + +P+ ARE L+ Q++ L I S G + + G L + G Sbjct: 3578 GYTPLNFEEIPTAGAREHY-------PLSSAQKR--LFILSQLEGGELSYNMPGILTVEG 3628 Query: 1366 ELNKAALETAYHKVLNRHESLRS---TISADGNEQIVASHANADIFFADILADYSALGDE 1422 L++ LE A+ ++++RH SLR+ T++ + +Q++ D+ F +Y+ L +E Sbjct: 3629 ALDRERLEQAFRRLIHRHGSLRTRFVTVNGEPVQQLLT-----DVPFT---VEYAELSEE 3680 Query: 1423 AINQALLKENAAAFDSVMGPLIRLRVLATARHEYLLALSAHHIIADGWSLIVFLQELAAL 1482 A L++ FD + PL+R+ ++ A +LL HHI++DG S+ + ++E Sbjct: 3681 EAG-ATLQQFVRPFDLGVAPLLRVGLIRIAHERHLLLFDMHHIVSDGVSMNILIEEFLRF 3739 Query: 1483 YSTECTGTRSLLPT-PTPFSDYAIWQKRMLESQPKEKAAAYWKNKFSVQTPAFELPSFRI 1541 Y E + P ++DYA+WQ+ LES+ + AYW + F P +LP + Sbjct: 3740 YQEE-----DVFPELQIQYTDYAVWQQEQLESERLKAQEAYWLDAFRGSLPVLDLPGDEV 3794 Query: 1542 RDAAGVRKGSRHRYVLDIPLTAKLKAVSQSMKVSLFTVLLSAYKVLLYRISNHKELVVGI 1601 R A G R + +D L+A L+ ++ +LF VLL+AY LL++ + ++++VG Sbjct: 3795 RPAVRSFAGDRIDFQIDSSLSASLQELATRTGSTLFMVLLAAYTALLHKYTGQEDVIVGS 3854 Query: 1602 PTAGQMQMGQKHLVGYCLNILPFSTTINPEMTFRXXXXXXXXXXXXXXXXQDYSYASLMK 1661 P AG+ + L+G + + T E F QDY + L++ Sbjct: 3855 PVAGRSHATLEGLIGMFVGTVALRTYPEGEKPFEAYLQEVKETALRAYENQDYPFEELVE 3914 Query: 1662 ELHSLDGSVHPPQINTMFNM------DKSLETPDFTGMDVELLQSPVSYSKYDLSMNIVE 1715 +L P +TMF + ++ +E FT D + +K+DL++ + E Sbjct: 3915 KLELQRDLSRNPLFDTMFVLQNIEQGEQEIEGLRFTPYD-----NVHPAAKFDLTLTVSE 3969 Query: 1716 LDHELMIDFEYDPNLFDTQIITGWANYFNRIL 1747 D L EY ++ + A +F +++ Sbjct: 3970 ADGALNCTLEYATAIYKQETAERMAGHFVQLI 4001 Score = 148 bits (373), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 108/387 (27%), Positives = 180/387 (46%), Gaps = 13/387 (3%) Query: 1365 GELNKAALETAYHKVLNRHESLRSTISADGNEQIVASHANADIFFADILADYSALGDEAI 1424 G L++ LE+A+ ++ RHESLR+ E + H N + FA L AL +E Sbjct: 1089 GLLDRTRLESAFQALIQRHESLRTGFYMQDGELVQRVHRN--VSFA--LNYTEALVEE-- 1142 Query: 1425 NQALLKENAAAFDSVMGPLIRLRVLATARHEYLLALSAHHIIADGWSLIVFLQELAALYS 1484 L+ AFD PL+R+ ++ +LL HHII+DG S+ + ++EL LY Sbjct: 1143 TDTLIHNFIRAFDLSQAPLLRVSLVKLQEERHLLLFDMHHIISDGVSIQILIEELTHLYQ 1202 Query: 1485 TECTGTRSLLPTPTPFSDYAIWQKRMLESQPKEKAAAYWKNKFSVQTPAFELPSFRIRDA 1544 E L + DYA+WQ+ E+Q ++ YW F + P +LP+ R + Sbjct: 1203 GE-----QLPELHIQYKDYAVWQREQSENQWQD-LEKYWLQSFEGELPVLDLPTDFQRPS 1256 Query: 1545 AGVRKGSRHRYVLDIPLTAKLKAVSQSMKVSLFTVLLSAYKVLLYRISNHKELVVGIPTA 1604 +GSR + LD ++ ++ +L+ VLL+AY VLL++ + +++VVG P A Sbjct: 1257 VRSFEGSRIDFTLDESGNKAIQELASRTGTTLYMVLLAAYSVLLHKYTGQEDIVVGSPVA 1316 Query: 1605 GQMQMGQKHLVGYCLNILPFSTTINPEMTFRXXXXXXXXXXXXXXXXQDYSYASLMKELH 1664 G+ Q + ++G +N L + + TF+ QDY + L+++L Sbjct: 1317 GRPQAELEGIIGMFVNTLALRSYPAGDKTFQDYLLEIKETALKAFEHQDYPFEKLVEKLG 1376 Query: 1665 SLDGSVHPPQINTMFNMDKS-LETPDFTGMDVELLQSPVSYSKYDLSMNIVELDHELMID 1723 P +T+ + + E D G+ +K+DLS+N+ E +L Sbjct: 1377 VGRDVSRNPLFDTLLVLQNTEQEEQDMDGVHFTPYLMDTVTAKFDLSLNVEEKGSKLAFG 1436 Query: 1724 FEYDPNLFDTQIITGWANYFNRILLAV 1750 EY L+ + + A + RIL AV Sbjct: 1437 LEYSTALYRRESVERLATHLLRILHAV 1463 Score = 134 bits (336), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 112/444 (25%), Positives = 219/444 (49%), Gaps = 55/444 (12%) Query: 3580 AYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPLQIVLGSSDFHLEFE 3639 +Y+ + + G + + L +F+ ++ +++ LRT F Y + +Q V + F L + Sbjct: 1078 SYNMPGVFTVDGLLDRTRLESAFQALIQRHESLRTGF-YMQDGELVQRVHRNVSFALNYT 1136 Query: 3640 DITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVYQMLWSFHHILMDGW 3699 + +E ++ + H + + FDL Q PL+R L+K + + +L+ HHI+ DG Sbjct: 1137 EAL-VEETDTLIH-------NFIRAFDLSQAPLLRVSLVKLQEERHLLLFDMHHIISDGV 1188 Query: 3700 CIGIVLKDMLEHYKQLNAGSRPSLETHQYRLYLDWLASKNK---EEAKVYWMQYLE---- 3752 I I+++++ Y+ P L QY+ Y W +++ ++ + YW+Q E Sbjct: 1189 SIQILIEELTHLYQ---GEQLPELHI-QYKDYAVWQREQSENQWQDLEKYWLQSFEGELP 1244 Query: 3753 ------DYKYKELLRKEGTSKEFRLAVLDIKLEEKVRTAVTHVASSSGITINSFFQAVWG 3806 D++ + EG+ +D L+E A+ +AS +G T+ A + Sbjct: 1245 VLDLPTDFQRPSVRSFEGSR-------IDFTLDESGNKAIQELASRTGTTLYMVLLAAYS 1297 Query: 3807 ILLSKYDNAEDVVFGAVISGR-SPEIEGIERMVGLFINTIPVRVRLSG-KTFHELAGEIQ 3864 +LL KY ED+V G+ ++GR E+EGI +G+F+NT+ +R +G KTF + EI+ Sbjct: 1298 VLLHKYTGQEDIVVGSPVAGRPQAELEGI---IGMFVNTLALRSYPAGDKTFQDYLLEIK 1354 Query: 3865 SSFISSEQYGYVPLSDI-------QAWSHRDLINHVMVFENYPLDREIRDTDGQQME-YG 3916 + + + ++ P + + S L + ++V +N ++E +D DG Y Sbjct: 1355 ETALKAFEHQDYPFEKLVEKLGVGRDVSRNPLFDTLLVLQN--TEQEEQDMDGVHFTPYL 1412 Query: 3917 FQIAGCEILEHTNYDFSI-IIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTAC 3975 + +D S+ + E G + Y+ Y +E++ L ++LL I+ V A Sbjct: 1413 MDTVTAK------FDLSLNVEEKGSKLAFGLEYSTALYRRESVERLATHLLRILHAVAAN 1466 Query: 3976 PQIEAGDVEVLSQEEKLKLMNVFN 3999 PQ++ ++E+++ EEK++++ VFN Sbjct: 1467 PQLQLAEIEMITPEEKVQIVEVFN 1490 Score = 125 bits (313), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 144/554 (25%), Positives = 246/554 (44%), Gaps = 64/554 (11%) Query: 1801 ILDKDMHPSPVGVPGEVYLA-------RLTEPSLLAEQ----PSTS------TGIMAMYT 1843 ILD+ + P+GV GE+Y+A L P L A++ P S TG +A Sbjct: 5880 ILDEQLRLVPLGVEGEMYIAGDGVARGYLNRPELTADKFIRNPFASEGNMYRTGDLARRL 5939 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKILAY- 1902 + +I+ IG + G I L I+ +L+ PL+ A V Q+ + AY Sbjct: 5940 PNGDIEYIGRIDHQVKIRGYRIELGEIEAKLLDIPLVEEALVVAWADAHGQK--SLCAYF 5997 Query: 1903 ITPRGTSIPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKALR 1962 + R S V E++ L + +P IPS F+ LD +PL G ++ + LP + Sbjct: 5998 VANREMS---VSELRDELSAGLPAYMIPSYFVQLDVMPLTPNGKLDRKALPEPNSGIKAG 6054 Query: 1963 EEIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDISL 2022 + P + E LA IW+ VL + LV +D+FFELGG+S+K S+ S + I + Sbjct: 6055 ADFTAPRTDVENILASIWQGVLGVPLVGIHDNFFELGGDSIK-SIQVSSRLLQAGYKIEM 6113 Query: 2023 RMLFEHPTVKGLAKAING----AGKSFLPEITPLGKKDWYPQSSSQKRLFAIEQMGGAGT 2078 + LF +PT+ LA+ ++ A +S + LG +Q R F + M Sbjct: 6114 KDLFGYPTIAELAQRVSVVSRIADQSEVHGAVRLG--------PAQHRFFDEQSMDLH-- 6163 Query: 2079 AYNITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFELLHDEPVQVIHDDIPFSISYSI 2138 +N + +L+ + + E +++ + H+ LR F ++ ++ + + YS+ Sbjct: 6164 HFNQSVMLYRRDGFNTDALAEVVRKIAEHHDALRLVFR-QGEQGLEAWNRSMGEGELYSL 6222 Query: 2139 A----EDEDEP--------ELVKRFILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIA 2186 DE +P E ++R I SL PLFR+ + ++ EH++I+ +HH+ Sbjct: 6223 QIHDLRDETDPASAIEAGAEAIQRSI---SLEDGPLFRLGLFRCAEGEHLLIV-IHHLAV 6278 Query: 2187 DGISANILCNDLISLYS----GE--NLPGLEVQYKDYTALHNEMLSNERIRQQGEYWQQL 2240 DG+S IL DL Y GE LP Y+ + + ++ Q+ YW ++ Sbjct: 6279 DGVSWRILFEDLQDGYEQAARGEAVKLPQKTDSYRAWVEGITQFANSLAAEQERGYWAEV 6338 Query: 2241 LSDDIPSLTLPLDFPRPPVQSFDGACYSVTLDSDLTRGLKVLSNR-LKTTLYTLLLASYN 2299 D + LP D + D +V + T +NR T + LLL + Sbjct: 6339 EGDGF--VPLPKDKVDSALLIKDSEAVTVRWSPEETEQFLKEANRTYNTEVNDLLLTALG 6396 Query: 2300 ILLSKYSNQEDIVI 2313 + + +++ E + I Sbjct: 6397 MAVHEWTGIERVGI 6410 Score = 104 bits (260), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 76/256 (29%), Positives = 122/256 (47%), Gaps = 21/256 (8%) Query: 1801 ILDKDMHPSPVGVPGEVYLA-------RLTEPSLLAEQ-------PSTS---TGIMAMYT 1843 ++D SPVGVPGE+ +A +P L AE+ P TG +A + Sbjct: 7400 MMDSASQVSPVGVPGELCIAGEGVARGYFNQPDLTAEKFIPHPYKPGARIYRTGDLARWL 7459 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKILAYI 1903 D I+ +G + G I L ++ Q++ P + AV + + + Q ++ Sbjct: 7460 PDGNIEYLGRIDHQVKIRGYRIELGEVEAQILKVPSV-QEAVALALADSTGSTQLCAYFV 7518 Query: 1904 TPRGTSIPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKALRE 1963 G + +RE L S +P IP+AF+ L ++PLN G ++ + LPA + Sbjct: 7519 AEEGLAAGVLREA---LASELPSYMIPTAFVQLAQMPLNPNGKLDRKALPAPEALLRSTA 7575 Query: 1964 EIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDISLR 2023 E + P +TE LA+IW VL ++ + D FFELGG+SLK L I + L+ Sbjct: 7576 EYIPPRTQTEVELAQIWTEVLGVQEIGVKDHFFELGGHSLKVLGLIQKISSGMGVQLPLQ 7635 Query: 2024 MLFEHPTVKGLAKAIN 2039 ++F PTV+ +A I+ Sbjct: 7636 LVFNLPTVEEMAHEIS 7651 Score = 94.0 bits (232), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 78/310 (25%), Positives = 139/310 (44%), Gaps = 36/310 (11%) Query: 1333 KLTEEQQQISLVIHSN-DTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRSTIS 1391 KLT Q+ ++ HS + H V+ E ++G + + ++ RH LR+ Sbjct: 6615 KLTPMQK--GMLFHSLLEPHSEVYFEQAKFEIQGAFYPEDFKRSLKYLMKRHAILRTNFH 6672 Query: 1392 ADGNE---QIVASHANADIFFADI-----------LADYSALGDEAINQALLKENAAAFD 1437 A + QIV D + D+ LA Y+A ++ A F+ Sbjct: 6673 AGWGDFPIQIVFKERACDFAYEDLHELEADEIQARLAAYTA-----------QDKARGFN 6721 Query: 1438 SVMGPLIRLRVLATARHEYLLALSAHHIIADGWSLIVFLQELAALYSTECTGTRSLLPTP 1497 L+R+ +L TA Y L S+HHII DGW + + LQE+ Y LP Sbjct: 6722 LAEEALLRVAILRTAEEAYHLLWSSHHIILDGWCMPLVLQEVFETYGVLREQREPELPAA 6781 Query: 1498 TPFSDYAIWQKRMLESQPKEKAAAYWKNKFSVQTPAFELPSFRIRDAAGVRKGSRHR--Y 1555 +S Y W LE Q +E+A++YW+ +LP + +A + + Sbjct: 6782 VSYSQYIQW----LEKQGEEEASSYWRGYLEGYEQQTKLPQAITQPSAKAEAYVSEKLVF 6837 Query: 1556 VLDIPLTAKLKAVSQSMKVSLFTVLLSAYKVLLYRISNHKELVVGIPTAGQMQM--GQKH 1613 LD LT +L+ V++ +V++ T++ +A+ ++L R + +++V G +G+ G + Sbjct: 6838 TLDAELTDRLEQVAKQHQVTMNTLMQAAWGIVLQRYNRSQDIVFGSVVSGRPAEIPGIES 6897 Query: 1614 LVGYCLNILP 1623 ++G +N +P Sbjct: 6898 MIGLFINTVP 6907 Score = 85.9 bits (211), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 72/296 (24%), Positives = 122/296 (41%), Gaps = 19/296 (6%) Query: 1349 DTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRSTI-SADGNE--QIVASHANA 1405 + H + E +G + A + V+ RH LR+ S G+E Q+V H A Sbjct: 2571 EPHTGAYFEQAAFDFKGSFDPTAFGHSLDAVVERHAILRTNFYSGWGSEPLQVVFRHRGA 2630 Query: 1406 DIFFADILADYSALGDEAINQALLKENAAAFDSVMGPLIRLRVLATARHEYLLALSAHHI 1465 + + D+ ++ + + K+ A F+ L+R+ +L T + L S HHI Sbjct: 2631 KLVYEDLREMNASQREAYLKTFGAKDKALGFNLAEDELLRVSILQTDEESFRLLWSFHHI 2690 Query: 1466 IADGWSLIVFLQELAALYSTECTGTRSLLPTPTPFSDYAIWQKRMLESQPKEKAAAYWKN 1525 + DGW + + QE+ Y G L P+S Y W LE Q + A+ YW Sbjct: 2691 VMDGWCVPLITQEVFEHYFALLEGREPQLAEVHPYSRYIEW----LEQQDEAAASNYWSR 2746 Query: 1526 KFSVQTPAFELPSFRIRDAAGVRKG-----SRHRYVLDIPLTAKLKAVSQSMKVSLFTVL 1580 + LP G KG + Y L LT +L+ V++ V++ +L Sbjct: 2747 YLAGYEQQTLLPQ-----VGGASKGEGYVAEKLNYPLSRELTERLEKVARDAHVTMNILL 2801 Query: 1581 LSAYKVLLYRISNHKELVVGIPTAGQMQM--GQKHLVGYCLNILPFSTTINPEMTF 1634 S + + L R + K++V G +G+ G ++G +N +P + F Sbjct: 2802 QSLWGIALQRYNGSKDVVYGSVVSGRPAEIPGIDRMIGLFINTIPVRVKTEENLPF 2857 Score = 84.0 bits (206), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 80/313 (25%), Positives = 140/313 (44%), Gaps = 17/313 (5%) Query: 1331 VLKLTEEQQQISLVIHSN-DTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRST 1389 V KLT Q+ ++ HS + + E LRG + ++ ++ RH LR+ Sbjct: 5100 VYKLTPMQK--GMLFHSLLEPDSSSYFEQATFELRGSFDVDIFFESFQALVQRHAILRTG 5157 Query: 1390 IS---ADGNEQIVASHANADIFFADILADYSALGDEAINQALLKEN-AAAFDSVMGPLIR 1445 AD Q+V + + D L D S EA +A + E+ F PL+R Sbjct: 5158 FYNNIADVPLQVVFKQRLIPLHYVD-LRDASMQEQEARIKAYIAEDMVKGFSLSEDPLMR 5216 Query: 1446 LRVLATARHEYLLALSAHHIIADGWSLIVFLQELAALYSTECTGTRSLLPTPTPFSDYAI 1505 + VL + L+ S HHI+ DGW + + QEL YS + + +LP P+S Y Sbjct: 5217 VTVLQKDQ-SCLVLWSFHHIVMDGWCIPIITQELFDYYSAKKQQVQPVLPPAQPYSRYIE 5275 Query: 1506 WQKRMLESQPKEKAAAYWKNKFSVQTPAFELPSFRIRDAAGVRKGSRHRYVLDI--PLTA 1563 W L++Q ++A+ YW LP + + A +VL + LT Sbjct: 5276 W----LDAQDDQEASTYWSQYLEDYDGNTVLPEGKTKSQAKEAGYVLKEHVLHLGASLTG 5331 Query: 1564 KLKAVSQSMKVSLFTVLLSAYKVLLYRISNHKELVVGIPTAGQMQ--MGQKHLVGYCLNI 1621 K+ V++ V++ T++ +A+ ++L R + ++V G +G+ G +++VG +N Sbjct: 5332 KMDVVAKRNHVTVNTLMQTAWGLILQRYNASSDVVFGGVVSGRPAEIAGIENMVGLFINT 5391 Query: 1622 LPFSTTINPEMTF 1634 +P + + F Sbjct: 5392 VPIRVQSSKDEAF 5404 Score = 82.4 bits (202), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 81/379 (21%), Positives = 167/379 (44%), Gaps = 19/379 (5%) Query: 1363 LRGELNKAALETAYHKVLNRHESLRSTI-SADG-NEQIVASHANADIFFADILADYSALG 1420 ++G +N AA + + ++ ++++ R I S DG +Q V + + D L+ Y ++ Sbjct: 37 MKGHINIAAFMQSINLIIKQYDAFRIRITSVDGVPQQYVVPYEERQLECLD-LSHYESVS 95 Query: 1421 D-EAINQALLKENAAAFDSVMGPLIRLRVLATARHEYLLALSAHHIIADGWSLIVFLQEL 1479 + EA+ + ++ DS L + ++ + EY + + HHII+DG S++V+ +L Sbjct: 96 EVEALLEQHKRKPLPLLDS---ELFQFLIVKISEEEYWINIKMHHIISDGISMVVYGNQL 152 Query: 1480 AALYSTECTGTRSLLPTPTPFSDYAIWQKRMLESQPKEKAAAYWKNKFSVQTPAFELPSF 1539 A Y G L + Y + S +K AYW +KFS P EL + Sbjct: 153 TAFYMELIQGNEPKLGDDCSYIQYIADENAYELSDRYQKDKAYWLDKFS-DLP--ELTGW 209 Query: 1540 RIRDAAGVRKGS-RHRYVLDIPLTAKLKAVSQSMKVSLFTVLLSAYKVLLYRISNHKELV 1598 + + + + R + + L +L+A Q ++SLF + A + +++++N ++V Sbjct: 210 KSYNPLSLSTHAVREHFTVPEVLYHELQAFCQQNRISLFQFFMGAMYIYIHKMTNQPDVV 269 Query: 1599 VGIPTAGQMQMGQKHLVGYCLNILPFSTTINPEMTFRXXXXXXXXXXXXXXXXQDYSYAS 1658 +G A + +K +G ++ T + ++ Q Y Y Sbjct: 270 IGTSFANRGNKKEKQKIGMFVSTAAARTYVKKDIDVLSFLQDVARDQMSVLRHQKYPYNQ 329 Query: 1659 LMKELHSLDGSVHPPQINTMFNMDKSLETPDFTGMDVELLQSPVSYSK---YDLSMNIVE 1715 L+++L + G+ I +F + ++ +D + + + D +IVE Sbjct: 330 LIQDLREMHGN---KDIQRLFGVSMEYRLINWVDLDDVRILTDYDFCGDEVNDFVFHIVE 386 Query: 1716 L--DHELMIDFEYDPNLFD 1732 + + EL++D +Y LF+ Sbjct: 387 ILDEGELVLDVDYRTELFE 405 Score = 79.7 bits (195), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 100/459 (21%), Positives = 191/459 (41%), Gaps = 39/459 (8%) Query: 3558 VYTMTPMQESMLFHALKNKRSDAYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFV 3617 +Y +T Q+ + + L + +KG I +S LI+ +YD R R Sbjct: 6 LYDLTNAQKRIWYTELLYPDTSVSQLSGTAKMKGHINIAAFMQSINLIIKQYDAFRIRIT 65 Query: 3618 YKKLHRPLQIVLGSSDFHLEFEDITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAIL 3677 P Q V+ + LE D++H ES ++ +E L + K L+ L + ++ Sbjct: 66 SVD-GVPQQYVVPYEERQLECLDLSHYES---VSEVEALLEQHKRKPLPLLDSELFQFLI 121 Query: 3678 LKTGDSVYQMLWSFHHILMDGWCIGIVLKDMLEHYKQLNAGSRPSLETHQYRLYLDWLAS 3737 +K + Y + HHI+ DG + + + Y +L G+ P L Y+ ++A Sbjct: 122 VKISEEEYWINIKMHHIISDGISMVVYGNQLTAFYMELIQGNEPKLGDDCS--YIQYIAD 179 Query: 3738 KNKEEA-------KVYWMQYLEDYKYKELLRKEG--TSKEFRLAVLDIKLEEKVRTAVTH 3788 +N E K YW+ K+ +L G + L+ ++ V + H Sbjct: 180 ENAYELSDRYQKDKAYWLD-----KFSDLPELTGWKSYNPLSLSTHAVREHFTVPEVLYH 234 Query: 3789 ----VASSSGITINSFFQAVWGILLSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINT 3844 + I++ FF I + K N DVV G + R + E ++ +G+F++T Sbjct: 235 ELQAFCQQNRISLFQFFMGAMYIYIHKMTNQPDVVIGTSFANRGNKKE--KQKIGMFVST 292 Query: 3845 IPVRVRLSGK----TFHELAGEIQSSFISSEQYGYVPL-SDIQAW-SHRDLINHVMVFEN 3898 R + +F + Q S + ++Y Y L D++ ++D+ V Sbjct: 293 AAARTYVKKDIDVLSFLQDVARDQMSVLRHQKYPYNQLIQDLREMHGNKDIQRLFGVSME 352 Query: 3899 YPLDREIRDTDGQQMEYGFQIAGCEILEHTNYDFSI--IIEPGEDFIIRIVYNALAYDKE 3956 Y L + D D ++ + G E+ ++ F I I++ GE ++ + Y +++ Sbjct: 353 YRLINWV-DLDDVRILTDYDFCGDEV---NDFVFHIVEILDEGE-LVLDVDYRTELFERS 407 Query: 3957 TISILESYLLAIIGQVTACPQIEAGDVEVLSQEEKLKLM 3995 + + S LL I Q+ PQ+ +V +L + E+ ++ Sbjct: 408 EVKDMVSQLLTIAEQIIHSPQLSIAEVSLLGEPEEQSIL 446 >A9LJA2.1 A9LJA2_PAEPO FusA Length = 7908 Score = 1595 bits (4130), Expect = 0.0, Method: Compositional matrix adjust. Identities = 870/2239 (38%), Positives = 1311/2239 (58%), Gaps = 64/2239 (2%) Query: 1801 ILDKDMHPSPVGVPGEVYLARL-------TEPSLLAEQ-------PSTS---TGIMAMYT 1843 ILD PVGV GE+ ++ + P L+ E+ P TG + + Sbjct: 3328 ILDDHFRLQPVGVAGELCISSIGLARGYHNRPELMDEKFVDNPFAPGERMYRTGDLVRWL 3387 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKILAYI 1903 + I+ +G + G I L ++ Q++ P + +D ++AY Sbjct: 3388 PNGNIEYLGRIDHQVKIRGYRIELGEVEAQMLRVPSVQEVVAMAVEGDDGYKD--LVAYF 3445 Query: 1904 TPRGTSIPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKALRE 1963 +V E++ L +PG IPS F+ L+++ L S G I+ + L A Sbjct: 3446 V--AAQKLEVSELRAVLSEMLPGYMIPSRFIQLEDMLLTSNGKIDRKALQGERGWAAASS 3503 Query: 1964 EIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDISLR 2023 E P E +LAEIW+ VL +E D+FF GG+SL+A+LL I+KE + +ISLR Sbjct: 3504 EA--PRTPLEIQLAEIWQEVLGVESAGVKDNFFHFGGHSLRAALLVSRIRKEMNREISLR 3561 Query: 2024 MLFEHPTVKGLAKAINGAGKSFLPEITPLGKKDWYPQSSSQKRLFAIEQMGGAGTAYNIT 2083 +FE PT++GLA+ I G EI G ++ YP SS+QKRLF + Q+ G +YN+ Sbjct: 3562 AVFESPTIEGLARVIEGYTPLNFEEIPTAGAREHYPLSSAQKRLFILSQLEGGELSYNMP 3621 Query: 2084 GILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFELLHDEPVQVIHDDIPFSISYSIAEDED 2143 GIL VEG LD R+E+AF+RL+ RH LRT F ++ EPVQ + D+PF++ Y+ +E+ Sbjct: 3622 GILTVEGALDRERLEQAFRRLIHRHGSLRTRFVTVNGEPVQQLLTDVPFTVEYAELSEEE 3681 Query: 2144 EPELVKRFILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGISANILCNDLISLYS 2203 +++F+ PF L APL RV ++ + H+++ DMHHI++DG+S NIL + + Y Sbjct: 3682 AGATLQQFVRPFDLGVAPLLRVGLIRIAHERHLLLFDMHHIVSDGVSMNILIEEFLRFYQ 3741 Query: 2204 GENL-PGLEVQYKDYTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQSF 2262 E++ P L++QY DY E L +ER++ Q YW +P L LP D RP V+SF Sbjct: 3742 EEDVFPELQIQYTDYAVWQQEQLGSERLKAQEAYWLDAFRGSLPVLDLPGDEVRPAVRSF 3801 Query: 2263 DGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRFN 2322 G +DS L+ L+ L+ R +TL+ +LLA+Y LL KY+ QED+++GSPVAGR + Sbjct: 3802 AGDRIDFQIDSSLSASLQELATRTGSTLFMVLLAAYTALLHKYTGQEDVIVGSPVAGRSH 3861 Query: 2323 YSTNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIERD 2382 + ++GMFV T+A+R P K F+ +L EVKE L A+ENQDYPFEEL+ KL ++RD Sbjct: 3862 ATLEGLIGMFVGTVALRTYPEGEKPFEAYLQEVKETALRAYENQDYPFEELVEKLELQRD 3921 Query: 2383 ISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYEFKNDVAKFDLILEVIENTENLTLNFE 2442 +SRNP+FD MFVLQ+++ + ++ +R Y+ + AKFDL L V E L E Sbjct: 3922 LSRNPLFDTMFVLQNIEQG--EQEIEGLRFTPYDNVHPAAKFDLTLTVSEVDGALNCTLE 3979 Query: 2443 YCAKLFQESTIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYPG 2502 Y ++++ T RM+ F++++ + N + LS +D++ +E RL+ ++ YP Sbjct: 3980 YATAIYKQETAERMAGHFVQLIREAIANPALPLSSLDIVTPQEKSRLMKAPDEAKADYPR 4039 Query: 2503 GKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILME 2562 KT++ LFEEQAARTP AVA+V + +++Y N + N +AR LR +G++PD GI+ + Sbjct: 4040 DKTIHALFEEQAARTPNAVAVVCEDAALSYSELNERANGLARTLRERGLQPDGLAGIMAD 4099 Query: 2563 HSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEFI 2622 S E+++ + A++KAGGAYVP+DP YP +RI+F+++DS +++LT L ++ F G + Sbjct: 4100 RSLEMVVGILAILKAGGAYVPVDPEYPEDRIHFMLEDSGAKLLLTQAHLEQRVSFAGNIV 4159 Query: 2623 DAASSKWYCGDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYVH 2682 + Y D SN P+ LAY+IYTSG+TG PKG + H+ + ++ DK Sbjct: 4160 SLDKTASYKEDVSNLQPAAGPNHLAYVIYTSGTTGKPKGTLIEHKNVVRLLF-NDKNMFD 4218 Query: 2683 GEAVD-FPLYSSIAFDLSVTLIYIPLISGNKVFIYSGVSYES--LLEAVVIDNQVDFIML 2739 +A D + L+ S FD SV +Y L++G ++ I ++ +S ++ D +V + Sbjct: 4219 FDAQDTWTLFHSFCFDFSVWEMYGALLNGGRLVIVPSLTAKSPDRFLQLLKDQKVTVLNQ 4278 Query: 2740 TPSHLKILGEYDL----SRLKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETT 2795 TP++ L + +L + L +R I GGEA P K + ++ + V++ N+YG TETT Sbjct: 4279 TPTYFYQLLQEELGHQAAELSLRMIIFGGEALTPALLKDWRTKYPQ-VQLINMYGITETT 4337 Query: 2796 VACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYLN 2855 V T+ + + IG I ++ Y++D+ + Q IGIPGEL +AG G++RGYLN Sbjct: 4338 VHVTYKEITELEIEQGRSNIGTTIPTLRAYILDEQRRPQPIGIPGELYVAGVGLARGYLN 4397 Query: 2856 REELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIENQ 2915 R ELT EKFV PF+ MYR+GDL R L DG++E+LGR+D QVKIRG+RIELGE+E + Sbjct: 4398 RPELTEEKFVAHPFEAGERMYRSGDLARWLPDGSMEYLGRIDHQVKIRGYRIELGEVEAK 4457 Query: 2916 LVKQPGVNKAAVIISTGPTDSRYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFFVQMK 2975 L+ P V +A V+ + + L Y+TAD + P +M+PS+F+Q++ Sbjct: 4458 LLHAPSVREAVVLAREDGSGQKVLIGYFTADQMLTVGELRKALAAELPAYMIPSYFMQLE 4517 Query: 2976 SIPLTASGKVDRKKLPDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSFIK 3035 +PLT +GK+DRK LP + Q Y P+ EE LA VW+ VLG +VG + F Sbjct: 4518 QMPLTPNGKLDRKALPAPEANVQTGAVYEPPRTKAEETLASVWQGVLGAQQVGIHDHFFD 4577 Query: 3036 LGGDSIKAIQIVSRLKKYGLSLEVKELFLHQNIKGISPFVKQNIKRHNQGTIEGPVKLTA 3095 LGGDSIKAIQ+ SRL + G LE+K+LF + I +SP+++ + QG I+G +L Sbjct: 4578 LGGDSIKAIQVSSRLFQAGYKLEMKDLFKYPTIAELSPYLQAAGRTAEQGEIKGAAELMP 4637 Query: 3096 IQKWFFEQNFAEMHHWNQSILLH-NERFDVQFIRQAFQRITEHHDALRMVYRHTGQAGVE 3154 IQ+WFFE++ AE HH+N +++L+ + FD +R +I HHDALRMV+R T +AG Sbjct: 4638 IQRWFFERHTAEPHHYNHAVMLYRKDGFDEAALRLTMDQIAIHHDALRMVFRPT-EAGYA 4696 Query: 3155 QSNRGL-AGELFSLEVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDY 3213 NRG GEL++L++ D+ +D T + A IQ DLE GPL KLGL+ +GD+ Sbjct: 4697 AWNRGTDEGELYTLDIADVRQVEDQTAAVQAQADAIQASFDLEGGPLFKLGLFHCDDGDH 4756 Query: 3214 LAIVIHHLVVDGVSWRIILDDFASCYLSLDNGEEAGLIEKSDSYQKWAEALEVYANSPKL 3273 L IVIHHL+VDGVSWRI+ +D A+ Y NG+ L +K+DSY W+E YA P L Sbjct: 4757 LLIVIHHLLVDGVSWRILFEDIAAGYEQALNGQAIILPQKTDSYLVWSEQATKYAAGPAL 4816 Query: 3274 LQELAYWTDVNRIAVPALPKDSEAGNGKIKDRYQTKTVLSEKETTNLLRHAGDAYQTETX 3333 +E AYW + + LPKD + G I+D S +ET LLR A AY TET Sbjct: 4817 DKERAYWQLIEEAILAPLPKDEDQKPGTIRDTESVTVTWSAQETDLLLRQANRAYHTETN 4876 Query: 3334 XXXXXXXXXXIKGWANVDRVRINMEGHGREALIQDLDITRTVGWFTSTYPLVLELANSHE 3393 I+ W ++++ +N+EGHGRE ++ DLDITRTVGWFT+ YP++L L E Sbjct: 4877 DLLLTALGAAIQRWTGMEQILVNLEGHGREMIVPDLDITRTVGWFTTQYPVLLNLQGRQE 4936 Query: 3394 LPLHIMTTKETIRQTPNKGMGYQVLKYLTSPELRAAVDFNVMPEISFNYLGQF-----GN 3448 + I KE +R+ P+KG+GY +LKY+ +PE +V F V PEISFNYLGQF GN Sbjct: 4937 VSARIKRIKENLREVPHKGIGYGLLKYI-APE--KSVGFGVEPEISFNYLGQFDQDLEGN 4993 Query: 3449 EASYGTFEICNTFMESTESPESHRPYAIDINAMIVGNRVEIRVDYNPGQFNEATMSRFAE 3508 S T + + T P+ YA+D+N MI ++ + + Y+ Q+ + T+S FAE Sbjct: 4994 ALSLSTHSVGKALSDLT--PQQ---YALDVNGMIAEGQLSLTITYSSRQYRKETVSHFAE 5048 Query: 3509 LLLNSLKLIISHCTREERIQRSPSDLTYKKLTFEELDDL--NRLYPGGITDVYTMTPMQE 3566 LL +SL +I HC +ER Q +PSD+ ++ LT E+LD L + G I DVY +T MQ+ Sbjct: 5049 LLQSSLSEVILHCVAQERSQLTPSDVLFQGLTLEQLDRLTAQTAHIGEIEDVYKLTAMQK 5108 Query: 3567 SMLFHALKNKRSDAYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPLQ 3626 MLFH+L S +Y EQ +L+G ++ ESF+ + ++ ILRT F PLQ Sbjct: 5109 GMLFHSLLEPDSSSYFEQATFELRGSFDVDIFFESFQALAQRHAILRTGFYNNIADVPLQ 5168 Query: 3627 IVLGSSDFHLEFEDITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVYQ 3686 + L + D+ E+ A ++ A D K F L + PLMR +L+ S Sbjct: 5169 VAFKQRLIPLHYVDLRDASMQEQEARIKAYIAEDMVKGFSLSEDPLMRVTVLQKDQSCL- 5227 Query: 3687 MLWSFHHILMDGWCIGIVLKDMLEHYKQLNAGSRPSLETHQ-YRLYLDWLASKNKEEAKV 3745 +LWSFHHI+MDGWCI I+ +++ ++Y +P L Q Y Y++WL +++++EA Sbjct: 5228 VLWSFHHIVMDGWCIPIITQELFDYYSAKKQQIQPVLPPAQPYSRYIEWLDAQDEQEAST 5287 Query: 3746 YWMQYLEDYKYKELLRKEGTSKEFRLAVLDIK-----LEEKVRTAVTHVASSSGITINSF 3800 YW QYLEDY +L + T + + A +K L + + VA + +T+N+ Sbjct: 5288 YWSQYLEDYDGNTVLPEGKTKSQAKEAGYVLKEHVLHLGASLTGKMDVVAKRNHVTVNTL 5347 Query: 3801 FQAVWGILLSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRLS-GKTFHEL 3859 Q WG++L +Y+ + DVVFG V+SGR EI GIE MVGLFINT+P+RV+ S + F ++ Sbjct: 5348 MQTAWGLILQRYNASSDVVFGGVVSGRPAEIAGIENMVGLFINTVPIRVQSSKDEAFVKV 5407 Query: 3860 AGEIQSSFISSEQYGYVPLSDIQAWS--HRDLINHVMVFENYPLDREIRDTDGQQMEYGF 3917 Q+ ++ Y PL +IQ + +DLI+H+M+FENYPLD ++ + G Q E Sbjct: 5408 MKRTQAQSLAGRAYDTYPLYEIQGKTTQKQDLISHIMIFENYPLDEQVEQS-GNQTEDNL 5466 Query: 3918 QIAGCEILEHTNYDFSIIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTACPQ 3977 ++A + E TNYDF++++ PGED + I YNA Y++E+I+ + +LL ++ QV A PQ Sbjct: 5467 EVANFTMFEQTNYDFNLVVIPGEDIKVCIRYNASVYEQESIARIGGHLLQMLDQVAARPQ 5526 Query: 3978 IEAGDVEVLSQEEKLKLMN 3996 ++E+++ EE++ L++ Sbjct: 5527 ATIQELEIVTSEERMNLLD 5545 Score = 1559 bits (4036), Expect = 0.0, Method: Compositional matrix adjust. Identities = 854/2233 (38%), Positives = 1295/2233 (57%), Gaps = 55/2233 (2%) Query: 1801 ILDKDMHPSPVGVPGEVYLA-------RLTEPSLLAEQ----PSTS------TGIMAMYT 1843 ILD+ PVGVPGE+Y+A L P L +E+ P + TG +A + Sbjct: 787 ILDEQRRLQPVGVPGELYIAGDGLARGYLNRPDLTSEKFVEHPYRAGERLYRTGDLARWL 846 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKIL-AY 1902 D I+ +G + G I L ++ Q++ P + V + ++ QK+L AY Sbjct: 847 PDGNIEYLGRIDHQVKIRGYRIELGEVEAQILKAPNVRETIVLARED---EQGQKLLCAY 903 Query: 1903 ITPRGTSIPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKALR 1962 P E++ L + +P IPS F+ L+++PL G ++ R LPA + Sbjct: 904 YVASSDLSPG--ELRAQLAAELPAYMIPSYFVRLEQMPLTPNGKLDRRALPAPESSVQSG 961 Query: 1963 EEIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDISL 2022 E + P E ++ IW+++L + V D+FFE+GG+SL+A++L I KE ISL Sbjct: 962 EAYLAPRTAVEAQMVLIWQDILGVARVGVRDNFFEIGGHSLRATVLVSRIHKELGCSISL 1021 Query: 2023 RMLFEHPTVKGLAKAINGAGKSFLPEITPLGKKDWYPQSSSQKRLFAIEQMGGAGTAYNI 2082 R +F+ PTV+ LA+ + + I + + YP SS+QKRL+ + QM G +YN+ Sbjct: 1022 REVFQSPTVESLAQLVKKHIPTLYESIPQATESEAYPVSSAQKRLYVLRQMDGGELSYNM 1081 Query: 2083 TGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFELLHDEPVQVIHDDIPFSISYSIAEDE 2142 G+ V+G LD R+E AFQ L++RHE LRT F + E VQ +H ++PF+++Y+ A E Sbjct: 1082 PGVFTVDGPLDRTRLESAFQALIRRHESLRTGFYMQDGELVQRVHRNVPFALNYTEASVE 1141 Query: 2143 DEPELVKRFILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGISANILCNDLISLY 2202 + L+ FI F L+QAPL RV +V + H+++ DMHHII+DG+S IL +L LY Sbjct: 1142 ETDTLIHNFIRAFDLSQAPLLRVSLVKLQEERHLLLFDMHHIISDGVSIQILIEELTHLY 1201 Query: 2203 SGENLPGLEVQYKDYTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQSF 2262 GE LP L +QYKDY E N+ + +YW Q ++P L LP DF RP V+SF Sbjct: 1202 QGEQLPELHIQYKDYAVWQREQSENQ-WQDLEKYWLQSFEGELPVLDLPTDFQRPSVRSF 1260 Query: 2263 DGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRFN 2322 +G+ TLD + ++ L++R TTLY +LLA+Y++LL KY+ QEDIV+GSPVAGR Sbjct: 1261 EGSRIDFTLDESGNKAIQELASRTGTTLYMVLLAAYSVLLHKYTGQEDIVVGSPVAGRPQ 1320 Query: 2323 YSTNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIERD 2382 ++GMFVNTLA+R+ P KTFQ++LLE+KE L+AFE+QDYPFE+L+ KLG+ RD Sbjct: 1321 AELEGIIGMFVNTLALRSYPTGDKTFQDYLLEIKETALKAFEHQDYPFEKLVEKLGVGRD 1380 Query: 2383 ISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYEFKNDVAKFDLILEVIENTENLTLNFE 2442 +SRNP+FD + VLQ+ + + +D + Y AKFDL L V E L E Sbjct: 1381 VSRNPLFDTLLVLQNTEQE--EQEMDGVHFTPYLMDTVTAKFDLSLNVEEKGSKLAFGLE 1438 Query: 2443 YCAKLFQESTIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYPG 2502 Y L++ ++ R + LR+L V N + L++I+++ EE +++ FN T+ YP Sbjct: 1439 YSTALYRRESVERFATHLLRVLHAVSVNPQLQLAEIEMITPEEKVQIVEVFNATSAPYPR 1498 Query: 2503 GKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILME 2562 KT+++LF EQA RTP ALV +TY K +++A+ LR G + V ++ Sbjct: 1499 DKTIHELFAEQAKRTPEQTALVFGDVQLTYLELEDKASRLAQTLRRLGTLREQPVAVMGG 1558 Query: 2563 HSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEFI 2622 S E++I M AV++AGGAYVPIDP YP +R+ +++ DS+ +++L KG + + Sbjct: 1559 RSIEMVIGMLAVLQAGGAYVPIDPDYPEDRVRYMLNDSDAKLLLVQKGELINVDYGIPIV 1618 Query: 2623 DAASSKWYCGDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYVH 2682 D +S + Y + + P + LAY+IYTSG+TG PKGVM H+ + V + YV Sbjct: 1619 DLSSKEAYAAEPAQPETAQGSQGLAYVIYTSGTTGRPKGVMVEHRNVVRLV--KETNYVE 1676 Query: 2683 -GEAVDFPLYSSIAFDLSVTLIYIPLISGNKVFIYSG--VSYESLLEAVVIDNQVDFIML 2739 E+ ++AFD S I+ L++G +++ + L+A + + + L Sbjct: 1677 LNESTRILQTGAVAFDASTFEIWGALLNGGQLYFVENDDILIADRLKAAIAKYGITTLWL 1736 Query: 2740 TP---SHLKILGEYDLSRLKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETTV 2796 T + L + EY LK ++GG+ + + + + + N YGPTE T Sbjct: 1737 TSPLFNQLSLQDEYLFRGLK--ALLVGGDVLSLSHMNRVIEANPDLIPI-NCYGPTENTT 1793 Query: 2797 ACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYLNR 2856 T Y+ P + VPIG PI N YVV+ + +LQ IG GEL + G+GV+RGYLNR Sbjct: 1794 FSTTYK-IPGR-AEGGVPIGRPISNSTAYVVNGSLQLQPIGAWGELIVGGEGVARGYLNR 1851 Query: 2857 EELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIENQL 2916 +LT EKFVP P + YRTGDLVR L DG++EF GR+D+QVKIRG+RIEL EIE QL Sbjct: 1852 PDLTAEKFVPSPVKDGEPCYRTGDLVRWLPDGDLEFKGRIDEQVKIRGYRIELPEIEAQL 1911 Query: 2917 VKQPGVNKAAVIISTGPTDSRYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFFVQMKS 2976 K V A V++ + LCAYY AD + P +M+PS+F+QM Sbjct: 1912 AKVESVIDAVVVVRADELGEKQLCAYYVADRTLTAGEVRLSLSQVLPGYMIPSYFIQMDR 1971 Query: 2977 IPLTASGKVDRKKLPDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSFIKL 3036 +PLT++GKVDR+ LP Y+AP+ EE LA VW+ VLG +VG ++F +L Sbjct: 1972 MPLTSNGKVDRRSLPAPQVGAHTGRKYTAPRTPAEEALASVWQGVLGAEQVGIHDNFFEL 2031 Query: 3037 GGDSIKAIQIVSRLKKYGLSLEVKELFLHQNIKGISPFVKQNIKRHNQGTIEGPVKLTAI 3096 GGDSIKAIQ+ SRL + G LE+K+LF I + ++ + QG + G +LT + Sbjct: 2032 GGDSIKAIQVSSRLLQAGYRLEMKQLFKSPTIAELGAEIQTAVHMAEQGVVRGTTRLTPV 2091 Query: 3097 QKWFFEQNFAEMHHWNQSILLHNER-FDVQFIRQAFQRITEHHDALRMVYRHTGQAGVEQ 3155 Q+WFF + AE HH+NQ+++L+ E+ F+ + + Q +++ EHHDALRMV+R T + G E Sbjct: 2092 QQWFFGRKQAEPHHFNQAVMLYREQGFEEKALHQVLRKLAEHHDALRMVFRQT-EHGYEA 2150 Query: 3156 SNRGL-AGELFSLEVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDYL 3214 NR L GEL+SL DL D T + + IQ+ I+L +GPLLKLGL+ +GD+L Sbjct: 2151 WNRDLEEGELYSLFTADLRNESDPTAAITSLSDDIQRSINLAEGPLLKLGLFHCQDGDHL 2210 Query: 3215 AIVIHHLVVDGVSWRIILDDFASCYLSLDNGEEAGLIEKSDSYQKWAEALEVYANSPKLL 3274 IVIHHLVVDGVSWRI+ +D A+ Y + G+ +K+DS++ W +AL Y+ P++ Sbjct: 2211 LIVIHHLVVDGVSWRILFEDIAAGYEQVIQGQALTFPQKTDSFRDWGDALARYSEGPEME 2270 Query: 3275 QELAYWTDVNRIAVPALPKDSEAGNGKIKDRYQTKTVLSEKETTNLLRHAGDAYQTETXX 3334 AYW ++ + LPKD + ++D + +ET LLR A AYQTET Sbjct: 2271 THRAYWRELEDQPLEQLPKDEAVESLLLQDSKVVTAQWTIEETDQLLRKAHRAYQTETND 2330 Query: 3335 XXXXXXXXXIKGWANVDRVRINMEGHGREALIQDLDITRTVGWFTSTYPLVLELANSHEL 3394 + W+ + +V +N+EGHGRE +I ++DITRTVGWFTS +P++L+L N+ E+ Sbjct: 2331 LLLTALGMAVSKWSGIGKVAVNLEGHGREPIIPNIDITRTVGWFTSQFPVILDLGNNPEV 2390 Query: 3395 PLHIMTTKETIRQTPNKGMGYQVLKYLTSPELRAAVDFNVMPEISFNYLGQFGNEASYGT 3454 I + KE +R+ PNKG+GY +LK + S + F++ PEISFNYLGQF + + Sbjct: 2391 ASLIKSVKEGLRRIPNKGIGYGLLKTMASQLDEGS--FSLQPEISFNYLGQFDQDLQGSS 2448 Query: 3455 FEICNTFMESTESPESHRPYAIDINAMIVGNRVEIRVDYNPGQFNEATMSRFAELLLNSL 3514 +I S +S Y +DIN M+ + + + YN Q+ +TM + A + SL Sbjct: 2449 LQISPYPTGSAQSLLEEPAYTLDINGMVTDGALTLTITYNGKQYKSSTMEQLAGYIEESL 2508 Query: 3515 KLIISHCTREERIQRSPSDLTYKKLTFEELDDLNRL--YPGGITDVYTMTPMQESMLFHA 3572 + ++ HC +E+ +PSD+ K L+ +L++L++ + G I +VY++TPMQ+ MLFH Sbjct: 2509 RELLQHCVTQEKTVLTPSDVLAKGLSIADLEELSKQTSHIGDIENVYSLTPMQKGMLFHD 2568 Query: 3573 LKNKRSDAYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPLQIVLGSS 3632 + + AY EQ D KG S +V ++ ILRT F PLQ+V Sbjct: 2569 MFEPHTGAYFEQAAFDFKGSFDPTAFGHSLDAVVERHAILRTNFYSGWGSEPLQVVFRHR 2628 Query: 3633 DFHLEFEDITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVYQMLWSFH 3692 L +ED+ M +S++ A+++ A D+ F+L + L+R +L+T + +++LWSFH Sbjct: 2629 GAKLVYEDLREMNASQREAYLKTFGAKDKALGFNLAEDELLRVSILQTDEESFRLLWSFH 2688 Query: 3693 HILMDGWCIGIVLKDMLEHYKQLNAGSRPSL-ETHQYRLYLDWLASKNKEEAKVYWMQYL 3751 HI+MDGWC+ ++ +++ EHY L G P L E H Y Y++WL +++ A YW +YL Sbjct: 2689 HIVMDGWCVPLITQEVFEHYFALLEGREPQLAEVHPYSRYIEWLEQQDEAVASNYWSRYL 2748 Query: 3752 EDYKYKELLRKEGTSKE---FRLAVLDIKLEEKVRTAVTHVASSSGITINSFFQAVWGIL 3808 Y+ + LL + G + + + L+ L ++ + VA + +T+N Q++WGI Sbjct: 2749 AGYEQQTLLPQVGGASKGEGYIAEKLNYPLSRELTERLEKVARDAHVTMNILLQSLWGIA 2808 Query: 3809 LSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRLSGKT-FHELAGEIQSSF 3867 L +Y+ + DVV+G+V+SGR EI GI+RM+GLFINTIPVRV+ F L + Q + Sbjct: 2809 LQRYNGSRDVVYGSVVSGRPAEIPGIDRMIGLFINTIPVRVKTEENLPFTVLMKQQQEQY 2868 Query: 3868 ISSEQYGYVPLSDIQAWS--HRDLINHVMVFENYPLDREIRDTDGQQMEYGFQIAGCEIL 3925 ++S YG PL +IQA + +DLI+H+MVFENYP++ E+ G + F+I E+L Sbjct: 2869 MASHMYGTYPLFEIQAQTDQKQDLISHIMVFENYPVEEEVERLGGGEAA--FEIEEAELL 2926 Query: 3926 EHTNYDFSIIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTACPQIEAGDVEV 3985 E TNYDF++I+ PGE+ + YNAL YD TI ++ +L+ ++ Q+ P I +E+ Sbjct: 2927 EQTNYDFNLIVLPGEEMRLLFQYNALVYDPVTIGQIKGHLVHLMEQIVENPAISVDALEL 2986 Query: 3986 LSQEEKLKLMNVF 3998 ++ +E+ +++NV+ Sbjct: 2987 ITPQEREQILNVW 2999 Score = 1267 bits (3279), Expect = 0.0, Method: Compositional matrix adjust. Identities = 717/2046 (35%), Positives = 1137/2046 (55%), Gaps = 64/2046 (3%) Query: 1991 TNDDFFELGGNSLKASLLAFSIQKEFSTDISLRMLFEHPTVKGLAKAINGAGKSFLPEIT 2050 T F EL +SL +L + +E S +LF+ T++ L + A + + EI Sbjct: 5042 TVSHFAELLQSSLSEVIL-HCVAQERSQLTPSDVLFQGLTLEQLDRLT--AQTAHIGEI- 5097 Query: 2051 PLGKKDWYPQSSSQKRLFAIEQMGGAGTAYNITGILHVEGKLDPGRMEEAFQRLVKRHEP 2110 +D Y ++ QK + + ++Y + G D E+FQ L +RH Sbjct: 5098 ----EDVYKLTAMQKGMLFHSLLEPDSSSYFEQATFELRGSFDVDIFFESFQALAQRHAI 5153 Query: 2111 LRTSF-ELLHDEPVQVIHDDIPFSISYSIAED---EDEPELVKRFILP-----FSLNQAP 2161 LRT F + D P+QV + Y D +++ +K +I FSL++ P Sbjct: 5154 LRTGFYNNIADVPLQVAFKQRLIPLHYVDLRDASMQEQEARIKAYIAEDMVKGFSLSEDP 5213 Query: 2162 LFRVHIVSRSDHEHIVIMDMHHIIADGISANILCNDLISLYSGEN------LPGLEVQYK 2215 L RV ++ + D +V+ HHI+ DG I+ +L YS + LP + Y Sbjct: 5214 LMRVTVLQK-DQSCLVLWSFHHIVMDGWCIPIITQELFDYYSAKKQQIQPVLPPAQ-PYS 5271 Query: 2216 DYTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQSFDGAC--YSVTLDS 2273 Y E L + ++ YW Q L D + LP + + + + L + Sbjct: 5272 RYI----EWLDAQDEQEASTYWSQYLEDYDGNTVLPEGKTKSQAKEAGYVLKEHVLHLGA 5327 Query: 2274 DLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRFN--YSTNNMVGM 2331 LT + V++ R T+ TL+ ++ ++L +Y+ D+V G V+GR NMVG+ Sbjct: 5328 SLTGKMDVVAKRNHVTVNTLMQTAWGLILQRYNASSDVVFGGVVSGRPAEIAGIENMVGL 5387 Query: 2332 FVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIERD-ISRNPVFD 2390 F+NT+ +R Q +K + F + + + +L YP E+ K ++D IS +F+ Sbjct: 5388 FINTVPIRVQSSKDEAFVKVMKRTQAQSLAGRAYDTYPLYEIQGKTTQKQDLISHIMIFE 5447 Query: 2391 VMFVLQSLDLAVPDVHLDDIRLNGYEFKNDVAKFDLILEVIENTENLTLNFEYCAKLFQE 2450 + + ++ + D++ + + +D L VI E++ + Y A ++++ Sbjct: 5448 NYPLDEQVEQSGNQTE-DNLEVANFTMFEQT-NYDFNLVVIPG-EDIKVCIRYNASVYEQ 5504 Query: 2451 STIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYPGGKTVYQLF 2510 +I R+ L++L V + +++++ EE L+ + A AYP + ++ LF Sbjct: 5505 ESIARIGGHLLQMLDQVAARPQATIQELEIVTSEERMNLL-DWGGKAHAYPSDQGLHTLF 5563 Query: 2511 EEQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILMEHSFELIIS 2570 EEQ RTP +A + ITY N + N++A L ++G++ + VG+L + S EL+++ Sbjct: 5564 EEQVVRTPDKIAAISGDIQITYRELNEQANRLASTLIAQGLRSEQVVGLLADRSVELLVA 5623 Query: 2571 MFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEFIDAASSKWY 2630 + V+KAGGAYVPIDP YP ERI +I+KDS EI+LT L + F+G ++ SS Y Sbjct: 5624 IMGVLKAGGAYVPIDPEYPQERIQYILKDSGAEILLTQSHLTKLASFEGMVMELDSSHIY 5683 Query: 2631 CGDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYVHGEAVDFPL 2690 +NP +DL Y+IYTSG+TG PKG M H+G+ NY+WW +K Y G+ DFPL Sbjct: 5684 GTGVNNPNIPVRGNDLVYLIYTSGTTGNPKGTMINHKGIVNYIWWANKVYCAGQPTDFPL 5743 Query: 2691 YSSIAFDLSVTLIYIPLISGNKVFIYSGVSYESLLEAVVIDNQVDFIMLTPSHLKILGEY 2750 YSSI+FDL++T ++ PLI+G V IY G+ +++ ++ +N VD + LTP+HL ++ + Sbjct: 5744 YSSISFDLTMTSMFTPLINGGIVRIYDGIDKAEVVQHILRENAVDILKLTPTHLSLIKDM 5803 Query: 2751 DL-SRLKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDL 2809 + + +I++ I+GGE +K ++++YN YGPTET V C + Y P KD Sbjct: 5804 AIPAESRIQQLIVGGENLTTHLSKIITDLFGGNIKIYNEYGPTETVVGCMIHLYDPAKDT 5863 Query: 2810 RNPVPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPF 2869 R VPIG P N+ ++++D+ +L +G+ GE+ IAGDGV+RGYLNR +LT EKF+ +PF Sbjct: 5864 RESVPIGLPSDNIYIHILDEQLRLVPLGVEGEMYIAGDGVARGYLNRPDLTAEKFIRNPF 5923 Query: 2870 QTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVII 2929 G MYRTGDL R L +G++E++GR+D QVKIRG+RIELGEIE +L+ P V +A V+ Sbjct: 5924 AAEGNMYRTGDLARRLPNGDIEYIGRIDHQVKIRGYRIELGEIEAKLLDIPLVEEALVVA 5983 Query: 2930 STGPTDSRYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFFVQMKSIPLTASGKVDRKK 2989 + LCAY+ AD M+ P +M+PS+FVQ+ +PLT +GK+DRK Sbjct: 5984 WADAHGQKSLCAYFVADREMSVSELRNELSAGLPAYMIPSYFVQLDVMPLTPNGKLDRKA 6043 Query: 2990 LPDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIVSR 3049 LP+ + ++AP+ +E LA +W+ VLG+ VG ++F +LGGDSIK+IQ+ SR Sbjct: 6044 LPEPNSGIKAGADFTAPRTDVENILASIWQGVLGVPLVGIHDNFFELGGDSIKSIQVSSR 6103 Query: 3050 LKKYGLSLEVKELFLHQNIKGISPFVKQNIKRHNQGTIEGPVKLTAIQKWFFEQNFAEMH 3109 L + G LE+K+LF + I ++ V + +Q + G V+L+ Q FF++ ++H Sbjct: 6104 LLQAGYKLEMKDLFGYPTIAELAQRVSVVSRIADQSEVHGSVRLSPAQHRFFDEQSMDLH 6163 Query: 3110 HWNQSILLH-NERFDVQFIRQAFQRITEHHDALRMVYRHTGQAGVEQSNRGLA-GELFSL 3167 H+NQS++L+ + F+ + + ++I EHHDALR+V+R G+ G+E NR + GEL+SL Sbjct: 6164 HFNQSVMLYRRDGFNTDALAEVVRKIAEHHDALRLVFRQ-GEQGLEAWNRSMGEGELYSL 6222 Query: 3168 EVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDYLAIVIHHLVVDGVS 3227 ++ DL D + AG + IQ+ I LE GPL +LGL++ G++L IVIHHL VDGVS Sbjct: 6223 QIHDLRDETDPASAIEAGAEAIQRSISLEDGPLFRLGLFRCAEGEHLLIVIHHLAVDGVS 6282 Query: 3228 WRIILDDFASCYLSLDNGEEAGLIEKSDSYQKWAEALEVYANSPKLLQELAYWTDVNRIA 3287 WRI+ +D Y GE +K+DSY+ W E + +ANSP QE +YW +V Sbjct: 6283 WRILFEDLQEGYEQAARGEAVKFPQKTDSYRAWVEGITQFANSPAAEQERSYWAEVEGDG 6342 Query: 3288 VPALPKDSEAGNGKIKDRYQTKTVLSEKETTNLLRHAGDAYQTETXXXXXXXXXXXIKGW 3347 LPKD G IKD S +ET L+ A Y TE + W Sbjct: 6343 FVPLPKDKVDGALLIKDSEAVTVRWSPEETEQFLKEANRTYNTEVNDLLLTALGMAVHEW 6402 Query: 3348 ANVDRVRINMEGHGREALIQDLDITRTVGWFTSTYPLVLELANSHELPLHIMTTKETIRQ 3407 ++RV I +EGHGRE ++ +LDITRT+GWFTS YP+ LE+ E+ I KE +R+ Sbjct: 6403 TGIERVGILLEGHGREPVVPELDITRTIGWFTSQYPVALEMGGELEIGARIKHVKEGLRR 6462 Query: 3408 TPNKGMGYQVLKYLTSPELRAAVDFNVMPEISFNYLGQFGNEASYGTFEICNTFMESTES 3467 PNKG+GY +LKYL+ F+ PEI+FNYLGQF + + G E+ + + S Sbjct: 6463 IPNKGVGYGILKYLSDGS--DVSSFSAEPEITFNYLGQFDQDLAGGMMEVSSYSVGPEVS 6520 Query: 3468 PESHRPYAIDINAMIVGNRVEIRVDYNPGQFNEATMSRFAELLLNSLKLIISHCTREERI 3527 + + A++IN +I ++++ V YN Q + ++++F +L N L +I HC +ER Sbjct: 6521 EQMVQHQAVNINGLIAEGQLQLSVSYNRHQLHGESVAKFVGILKNRLSEVIGHCVSKERT 6580 Query: 3528 QRSPSDLTYKKLTFEELDDLNR--LYPGGITDVYTMTPMQESMLFHALKNKRSDAYHEQC 3585 + +PSD+ K ++ E++++L + G I ++Y +TPMQ+ MLFH+L S+ Y EQ Sbjct: 6581 ELTPSDVLLKDISLEKIEELEEQTRHIGSIENMYKLTPMQKGMLFHSLLEPHSEVYFEQA 6640 Query: 3586 ILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPLQIVLGSSDFHLEFEDITHME 3645 +++G E S K ++ ++ ILRT F P+QIV +ED+ +E Sbjct: 6641 KFEIQGAFYPEDFKRSLKYLMKRHAILRTNFHAGWGDFPIQIVFKERACDFVYEDLHELE 6700 Query: 3646 SSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVYQMLWSFHHILMDGWCIGIVL 3705 + E A + A D+ + F+L + L+R +L+T + Y +LWS HHI++DGWC+ +VL Sbjct: 6701 ADEIQARLAAYTAQDKARGFNLAEEALLRVAILRTAEEAYHLLWSSHHIILDGWCMPLVL 6760 Query: 3706 KDMLEHYKQLNAGSRPSLETH-QYRLYLDWLASKNKEEAKVYWMQYLEDYKYKELL---- 3760 +++ E Y L P L Y Y+ WL + +EEA YW YLE Y+ + L Sbjct: 6761 QEVFETYGALREQREPELPAAVSYSQYIQWLEKQGEEEASSYWRGYLEGYEQQTKLPQAI 6820 Query: 3761 -----RKEGTSKEFRLAVLDIKLEEKVRTAVTHVASSSGITINSFFQAVWGILLSKYDNA 3815 + E E + LD +L +++ VA +T+N+ QA WGI+L +Y+ + Sbjct: 6821 TQPSAKAEAYVSEKLVFTLDAELTDRLE----QVAKQHQVTMNTLMQAAWGIVLQRYNRS 6876 Query: 3816 EDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRLSGK-TFHELAGEIQSSFISSEQYG 3874 +DVVFG+V+SGR EI GIE M+GLFINT+PVRV+ G +F + Q +++ Y Sbjct: 6877 QDVVFGSVVSGRPAEIPGIESMIGLFINTVPVRVQAEGSDSFSHVMKRQQELYLAGHAYD 6936 Query: 3875 YVPLSDIQAWSH--RDLINHVMVFENYPLDREIRDTDGQQMEYGFQIAGCEILEHTNYDF 3932 PL +IQA S +DLI+H+MVFENYP++ + + E ++I ++ E TNYDF Sbjct: 6937 SYPLYEIQAQSEQKQDLISHIMVFENYPVEEHLEEKIAND-EAEYKITDVQMFEQTNYDF 6995 Query: 3933 SIIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTACPQIEAGDVEVLSQEEKL 3992 ++I+ PG YNA YD+E++ ++ +L I+ V+ P I ++E+++ EEK Sbjct: 6996 NLIVLPGRSLEFLYRYNARVYDRESVERIQGHLTRILTSVSVQPAIRIDELELITPEEKS 7055 Query: 3993 KLMNVF 3998 +++ V+ Sbjct: 7056 QIIEVW 7061 Score = 620 bits (1600), Expect = e-175, Method: Compositional matrix adjust. Identities = 386/1214 (31%), Positives = 645/1214 (53%), Gaps = 51/1214 (4%) Query: 2058 YPQSSSQKRLFAIEQMGGAGTAYNITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFEL 2117 Y +++QKR++ E + + ++G ++G ++ ++ ++K+++ R Sbjct: 7 YDLTNAQKRIWYTELLYPDTSVSQLSGTAKMKGHINIAAFMQSINLIIKQYDAFRIRITS 66 Query: 2118 LHDEPVQVIHDDIPFS--------ISYSIAEDEDEPELVKRFILPFSLNQAPLFRVHIVS 2169 + P Q + +P+ +S+ + E E L + P L + LF+ IV Sbjct: 67 VDGLPQQYV---VPYEERQLECLDLSHYESVSEVEALLEQHKSKPLPLLDSELFQFLIVK 123 Query: 2170 RSDHEHIVIMDMHHIIADGISANILCNDLISLY-----SGENLPGLEVQYKDYTALHNEM 2224 S+ E+ + + MHHII+DGIS + N L Y E G + Y Y + N Sbjct: 124 ISEEEYWINIKMHHIISDGISMVVYGNKLTEFYMELIQGNEPQLGEDCSYIQYISDENAY 183 Query: 2225 LSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQSFDGACYSVTLDSDLTRGLKVLSN 2284 ++R ++ YW SD +P LT + P S T+ L L+ Sbjct: 184 ELSDRYQKDKAYWLDKFSD-LPELTGWKSY-NPLSLSTHAVREHFTVPEVLYHELQAFCQ 241 Query: 2285 RLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRFNYSTNNMVGMFVNTLAMRNQPAK 2344 + + +L+ + + I + K +NQ D+VIG+ A R N +GMFV+T A R K Sbjct: 242 QNRISLFQFFMGAMYIYIHKMTNQPDVVIGTSFANRGNKKEKQKIGMFVSTAAARTYVKK 301 Query: 2345 HKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIERDISRNPVFDVMFVLQSLDLAVPD 2404 FL +V + + +Q YP+ +LI L R++ N +F + + Sbjct: 302 DMDVLSFLQDVARDQMSVLRHQKYPYNQLIQDL---REMHGNKDIQRLFGVSMEYRLINW 358 Query: 2405 VHLDDIR-LNGYEFKNDVAKFDLILEVIE--NTENLTLNFEYCAKLFQESTIIRMSERFL 2461 V LDD+R L Y+F D D +L ++E + L L+ +Y +LF+ S + M + L Sbjct: 359 VDLDDVRILTDYDFCGDEVN-DFVLHIVEILDEGELVLDVDYRTELFERSEVKDMVSQLL 417 Query: 2462 RILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYPGGKTVYQLFEEQAARTPGAV 2521 I ++ + + +++++LL + E ++ A YP KT++ LFEEQA RTP V Sbjct: 418 TIAEQIIHSPQLSIAEVNLLGEPEEQSILALSEGAAVDYPREKTIHGLFEEQAERTPDHV 477 Query: 2522 ALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILMEHSFELIISMFAVMKAGGAY 2581 A+ +SITY N + NQ+AR LRS+GV DT VGI+ + S E++I M A++KAGGAY Sbjct: 478 AVQMDEQSITYLALNEQANQLARYLRSEGVGADTLVGIMADRSLEMVIGMLAILKAGGAY 537 Query: 2582 VPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEFIDAASSKWYCGDDSNPVSVN 2641 VPIDP YP ERI+++++DS + ++LT L E F G+ + + Y GD SN S++ Sbjct: 538 VPIDPDYPEERIHYMLEDSGVRLLLTQSHLWESTTFDGKLVSLDEATTYTGDASNLESIS 597 Query: 2642 SPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYVHGEAVDFPLYSSIAFDLSVT 2701 P LAY+IYTSG+TG PKG + H+ + ++ + + L+ S FD SV Sbjct: 598 GPSHLAYVIYTSGTTGKPKGTLIEHKNVVRLLFNDKNLFDFSSQDTWTLFHSFCFDFSVW 657 Query: 2702 LIYIPLISGNKVFIYSGVSYES---LLEAVVIDNQVDFIMLTPSHL-KILGE---YDLSR 2754 +Y L+ G K+ I ++ +S LE ++ DNQV + TP++ ++L E + + Sbjct: 658 EMYGALLYGGKLVIVPSLTAKSPAAFLE-LLKDNQVTILNQTPTYFYQVLQEELTHSSTE 716 Query: 2755 LKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDLRNPVP 2814 L +RK I GGEA P + + + DV++ N+YG TETTV T+ + Sbjct: 717 LGLRKIIFGGEALSPSLLRNWRVKYP-DVQLINMYGITETTVHVTYKEITEHEIEAGKSN 775 Query: 2815 IGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPFQTSGM 2874 IG I + Y++D+ +LQ +G+PGEL IAGDG++RGYLNR +LT EKFV P++ Sbjct: 776 IGRTIPTLSAYILDEQRRLQPVGVPGELYIAGDGLARGYLNRPDLTSEKFVEHPYRAGER 835 Query: 2875 MYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVIISTGPT 2934 +YRTGDL R L DGN+E+LGR+D QVKIRG+RIELGE+E Q++K P V + V+ Sbjct: 836 LYRTGDLARWLPDGNIEYLGRIDHQVKIRGYRIELGEVEAQILKAPNVRETIVLAREDEQ 895 Query: 2935 DSRYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFFVQMKSIPLTASGKVDRKKLPDSF 2994 + LCAYY A ++ P +M+PS+FV+++ +PLT +GK+DR+ LP Sbjct: 896 GQKLLCAYYVASSDLSPGELRAQLAAELPAYMIPSYFVRLEQMPLTPNGKLDRRALPAPE 955 Query: 2995 ESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIVSRL-KKY 3053 S Q +AY AP+ +E ++ L+W+++LG+ +VG ++F ++GG S++A +VSR+ K+ Sbjct: 956 SSVQSGEAYLAPRTAVEAQMVLIWQDILGVARVGVRDNFFEIGGHSLRATVLVSRIHKEL 1015 Query: 3054 GLSLEVKELFLHQNIKGISPFVKQNI----KRHNQGTIEGPVKLTAIQKWFF---EQNFA 3106 G S+ ++E+F ++ ++ VK++I + Q T +++ QK + + + Sbjct: 1016 GCSISLREVFQSPTVESLAQLVKKHIPTLYESIPQATESEAYPVSSAQKRLYVLRQMDGG 1075 Query: 3107 EMHHWNQSILLHNERFDVQFIRQAFQRITEHHDALRMVYRHTGQAGVEQSNRGLAGELFS 3166 E+ + + + D + AFQ + H++LR + V++ +R + F+ Sbjct: 1076 ELSYNMPGVFTVDGPLDRTRLESAFQALIRRHESLRTGFYMQDGELVQRVHRNVP---FA 1132 Query: 3167 LEVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDYLAIV-IHHLVVDG 3225 L T+ + ++ L+H I + DL + PLL++ L + +L + +HH++ DG Sbjct: 1133 LNYTEAS-VEETDTLIHNFI----RAFDLSQAPLLRVSLVKLQEERHLLLFDMHHIISDG 1187 Query: 3226 VSWRIILDDFASCY 3239 VS +I++++ Y Sbjct: 1188 VSIQILIEELTHLY 1201 Score = 529 bits (1362), Expect = e-147, Method: Compositional matrix adjust. Identities = 326/1011 (32%), Positives = 534/1011 (52%), Gaps = 47/1011 (4%) Query: 2086 LHVEGKLDPGRMEEAFQRLVKRHEPLRTSFEL-LHDEPVQVIHDDIPFSISYSIAEDEDE 2144 ++G P + + + L+KRH LRT+F D P+Q++ + Y + + Sbjct: 6642 FEIQGAFYPEDFKRSLKYLMKRHAILRTNFHAGWGDFPIQIVFKERACDFVYEDLHELEA 6701 Query: 2145 PELVKRFIL--------PFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGISANILCN 2196 E+ R F+L + L RV I+ ++ + ++ HHII DG ++ Sbjct: 6702 DEIQARLAAYTAQDKARGFNLAEEALLRVAILRTAEEAYHLLWSSHHIILDGWCMPLVLQ 6761 Query: 2197 DLISLYSG------ENLPGLEVQYKDYTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTL 2250 ++ Y LP V Y Y + L + + YW+ L L Sbjct: 6762 EVFETYGALREQREPELPA-AVSYSQYI----QWLEKQGEEEASSYWRGYLEGYEQQTKL 6816 Query: 2251 PLDFPRPPV--QSFDGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQ 2308 P +P +++ TLD++LT L+ ++ + + T+ TL+ A++ I+L +Y+ Sbjct: 6817 PQAITQPSAKAEAYVSEKLVFTLDAELTDRLEQVAKQHQVTMNTLMQAAWGIVLQRYNRS 6876 Query: 2309 EDIVIGSPVAGRFNY--STNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQ 2366 +D+V GS V+GR +M+G+F+NT+ +R Q +F + +E L Sbjct: 6877 QDVVFGSVVSGRPAEIPGIESMIGLFINTVPVRVQAEGSDSFSHVMKRQQELYLAGHAYD 6936 Query: 2367 DYPFEELISKLGIERD-ISRNPVFDVMFVLQSLDLAVP----DVHLDDIRLNGYEFKNDV 2421 YP E+ ++ ++D IS VF+ V + L+ + + + D+++ F+ Sbjct: 6937 SYPLYEIQAQSEQKQDLISHIMVFENYPVEEHLEEKIANDEAEYKITDVQM----FEQTN 6992 Query: 2422 AKFDLILEVIENTENLTLNFEYCAKLFQESTIIRMSERFLRILTTVVENCNVLLSDIDLL 2481 F+LI + +L + Y A+++ ++ R+ RILT+V + + +++L+ Sbjct: 6993 YDFNLI---VLPGRSLEFLYRYNARVYDRESVERIQGHLTRILTSVSVQPAIRIDELELI 7049 Query: 2482 PKEETDRLIYTFNDTATAYPGGKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQ 2541 EE ++I + DTA YP KT++ +FEE+AA TP AL++ +TY +++ N+ Sbjct: 7050 TPEEKSQIIEVWGDTAAPYPREKTLHGIFEEKAALTPDRTALIYGETVLTYGELHQQANR 7109 Query: 2542 MARMLRSKGVKPDTTVGILMEHSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSN 2601 +AR LR +GV+PD VGI++E S E+II + A++KAGGAYVPIDP +P +RI +++DS Sbjct: 7110 LARTLRVQGVRPDQPVGIMVERSLEMIIGIHAILKAGGAYVPIDPGFPEDRIRHMLEDSG 7169 Query: 2602 LEIMLTHKGLAEKCQFQGEFIDAASSKWYCGDDSNPVSVNSPDDLAYIIYTSGSTGLPKG 2661 +++LT L ++ F G + + Y DDSN V P+ LAYIIYTSGSTG PKG Sbjct: 7170 AKLLLTKNHLKDRFPFTGTILSLDDPQAYHADDSNLEPVAGPEHLAYIIYTSGSTGKPKG 7229 Query: 2662 VMTRHQGLTNYVWWGDKTYVHGEAVDFPLYSSIAFDLSVTLIYIPLI-SGNKVFIYSGVS 2720 VM H + + + Y F L ++ FD SV ++ G V + GV Sbjct: 7230 VMIEHHSAVHTLSQLEAEYPMLAGDRFLLKTTFTFDFSVPELFCWFFGQGTLVILPPGVD 7289 Query: 2721 YE--SLLEAVVIDNQVDFIMLTPSHLKILGEY-----DLSRLKIRKFIIGGEAFDPFYAK 2773 + +LLEAV NQ+ + L PS L +L +Y L ++ GE + Sbjct: 7290 KDPVALLEAVDA-NQITHLNLVPSMLSVLVQYLKESSTQGFLTLKYLFACGETLPAKLVE 7348 Query: 2774 KFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVDQNGKL 2833 +++ +++ + N+YGPTE V T Y + VPIG P NVQ++++D ++ Sbjct: 7349 EYY-KVSPYAVLENIYGPTEAAVYATRYTTSLETAALTHVPIGKPYANVQVWMMDSASQV 7407 Query: 2834 QGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFL 2893 +G+PGELCIAG+GV+RGY N+ +LT EKF+P P++ +YRTGDL R + DGN+E+L Sbjct: 7408 SPVGVPGELCIAGEGVARGYFNQPDLTAEKFIPHPYKPGERIYRTGDLARWVPDGNIEYL 7467 Query: 2894 GRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVIISTGPTDSRYLCAYYTADFPMNXXX 2953 GR+D QVKIRG+RIELGE+E Q++K P V +A V+ T S LCAY+ A+ + Sbjct: 7468 GRIDHQVKIRGYRIELGEVEAQILKVPSVQEAVVLALADSTGSTQLCAYFVAEEGLAAGV 7527 Query: 2954 XXXXXXXXXPRHMVPSFFVQMKSIPLTASGKVDRKKLPDSFESFQMEDAYSAPQNFIEEK 3013 P +M+P+ FVQ+ +PL +GK+DRK LP + Y AP+ E + Sbjct: 7528 LREALASELPSYMIPTAFVQLAQMPLNPNGKLDRKALPAPETLLRSTAEYIAPRTQTEVE 7587 Query: 3014 LALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIVSRLKK-YGLSLEVKELF 3063 LA +W EVLG+ ++G + F +LGG S+K + ++ R+ G+ L ++ +F Sbjct: 7588 LAQIWSEVLGVQEIGIRDHFFELGGHSLKVLGLIQRISSGMGVQLPLQVVF 7638 Score = 506 bits (1302), Expect = e-140, Method: Compositional matrix adjust. Identities = 373/1252 (29%), Positives = 614/1252 (49%), Gaps = 79/1252 (6%) Query: 2079 AYNITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSF-ELLHDEPVQVIHDDIPFSISYS 2137 AY +G DP + +V+RH LRT+F EP+QV+ + Y Sbjct: 2576 AYFEQAAFDFKGSFDPTAFGHSLDAVVERHAILRTNFYSGWGSEPLQVVFRHRGAKLVYE 2635 Query: 2138 IAEDEDEPE---LVKRF-----ILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGI 2189 + + + +K F L F+L + L RV I+ + ++ HHI+ DG Sbjct: 2636 DLREMNASQREAYLKTFGAKDKALGFNLAEDELLRVSILQTDEESFRLLWSFHHIVMDGW 2695 Query: 2190 SANILCNDLISLYSGENLPGLEVQYKDYTALHNEMLSNERIRQQGE-----YWQQLLSDD 2244 ++ ++ Y L G E Q + +H E + QQ E YW + L+ Sbjct: 2696 CVPLITQEVFEHYFA-LLEGREPQLAE---VHPYSRYIEWLEQQDEAVASNYWSRYLAGY 2751 Query: 2245 IPSLTLPLDFPRPPVQSFDGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSK 2304 LP + + + L +LT L+ ++ T+ LL + + I L + Sbjct: 2752 EQQTLLPQVGGASKGEGYIAEKLNYPLSRELTERLEKVARDAHVTMNILLQSLWGIALQR 2811 Query: 2305 YSNQEDIVIGSPVAGRFNY--STNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEA 2362 Y+ D+V GS V+GR + M+G+F+NT+ +R + ++ F + + +E + + Sbjct: 2812 YNGSRDVVYGSVVSGRPAEIPGIDRMIGLFINTIPVRVKTEENLPFTVLMKQQQEQYMAS 2871 Query: 2363 FENQDYPFEELISKLGIERD-ISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYEFKNDV 2421 YP E+ ++ ++D IS VF+ V + ++ RL G E ++ Sbjct: 2872 HMYGTYPLFEIQAQTDQKQDLISHIMVFENYPVEEEVE-----------RLGGGEAAFEI 2920 Query: 2422 AKFDLILE-------VIENTENLTLNFEYCAKLFQESTIIRMSERFLRILTTVVENCNVL 2474 + +L+ + ++ E + L F+Y A ++ TI ++ + ++ +VEN + Sbjct: 2921 EEAELLEQTNYDFNLIVLPGEEMRLLFQYNALVYDPVTIGQIKGHLVHLMEQIVENPAIS 2980 Query: 2475 LSDIDLLPKEETDRLIYTFNDTATAYPGGKTVYQLFEEQAARTPGAVALVHQGESITYEH 2534 + ++L+ +E ++++ + +T Y T + L EEQA RTP A A+ + ES+TY Sbjct: 2981 VDALELITPQEREQILNVWGNTKAIYEHYNTFHGLLEEQAGRTPDAAAIWFEDESLTYAE 3040 Query: 2535 FNRKTNQMARMLRSKGVKPDTTVGILMEHSFELIISMFAVMKAGGAYVPIDPTYPSERIN 2594 N K N +AR LR++G+K VG++ E S E+I+ ++ +MKAGGAYVPIDP YP ERI+ Sbjct: 3041 LNAKANGLARRLRTQGIKTGDLVGLIAERSLEMIVGIYGIMKAGGAYVPIDPEYPQERIS 3100 Query: 2595 FIIKDSNLEIMLTHKGLAEKCQFQGEFIDAASSKWYCGDDSNPVSVNSPDDLAYIIYTSG 2654 ++++DS +++LT L E + + S Y D SN PDDLAY+IYTSG Sbjct: 3101 YMLEDSGAKLILTQAHLLEHLGWTENVLLLDESSTYDADTSNLEDTAGPDDLAYVIYTSG 3160 Query: 2655 STGLPKGVMTRHQGLTNYVWWGDKTYVHGEAV---DFPLYSSIAFDLSVTLIYIPLISGN 2711 +TG PKGV+ H+GL N D H E ++S++FD SV+ I L G Sbjct: 3161 TTGQPKGVLVEHRGLPNL---SDVYGAHFEVTPQDRIVQFASLSFDASVSEILTALSHGG 3217 Query: 2712 KVFIYSG--VSYESLLEAVVIDNQVDFIMLTPSHLKILGEYDLSRL-KIRKFIIGGEAFD 2768 + I S + +L E + D + L P++ L D RL +R + G Sbjct: 3218 VLCIPSAQDILDHALFEQFMNDKGITVATLPPAYAIHL---DPERLPTLRCLLTAGST-- 3272 Query: 2769 PFYAKKFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVD 2828 + + + V N YGPTE +V T + ++ N V IG PI N +Y++D Sbjct: 3273 --ASIELIEEWRKHVRYSNGYGPTEDSVCTTIWSVPDSEEATNIVSIGRPIANHSVYILD 3330 Query: 2829 QNGKLQGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPFQTSGMMYRTGDLVRMLQDG 2888 + +LQ +G+ GELCI+ G++RGY NR EL EKFV +PF MYRTGDLVR L +G Sbjct: 3331 DHFRLQPVGVAGELCISSIGLARGYHNRPELMDEKFVDNPFAPGERMYRTGDLVRWLPNG 3390 Query: 2889 NVEFLGRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVIISTGPTDSRYLCAYYTADFP 2948 N+E+LGR+D QVKIRG+RIELGE+E Q+++ P V + + G + L AY+ A Sbjct: 3391 NIEYLGRIDHQVKIRGYRIELGEVEAQMLRVPSVQEVVAMAVEGDDGYKDLVAYFVAAQK 3450 Query: 2949 MNXXXXXXXXXXXXPRHMVPSFFVQMKSIPLTASGKVDRKKLPDSFESFQMEDAYSAPQN 3008 + P +M+PS F+Q++ + LT++GK+DRK L E + AP+ Sbjct: 3451 LEVSELRAVLSEMLPGYMIPSRFIQLEDMLLTSNGKIDRKALQG--ERGWAAASSEAPRT 3508 Query: 3009 FIEEKLALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIVSRLKK-YGLSLEVKELFLHQN 3067 +E +LA +W+EVLG+ G ++F GG S++A +VSR++K + ++ +F Sbjct: 3509 PLEIQLAEIWQEVLGVESAGVKDNFFHFGGHSLRAALLVSRIRKEMNREISLRAVFESPT 3568 Query: 3068 IKGISPFVKQ----NIKRHNQGTIEGPVKLTAIQKWFF---EQNFAEMHHWNQSILLHNE 3120 I+G++ ++ N + L++ QK F + E+ + IL Sbjct: 3569 IEGLARVIEGYTPLNFEEIPTAGAREHYPLSSAQKRLFILSQLEGGELSYNMPGILTVEG 3628 Query: 3121 RFDVQFIRQAFQRITEHHDALRMVYRHTGQAGVEQSNRGLAGELFSLEVTDLTGCDDHTD 3180 D + + QAF+R+ H +LR + V+Q L F++E +L+ + Sbjct: 3629 ALDRERLEQAFRRLIHRHGSLRTRFVTVNGEPVQQL---LTDVPFTVEYAELS-----EE 3680 Query: 3181 LMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDYLAIV-IHHLVVDGVSWRIILDDFASCY 3239 A ++ + DL PLL++GL + + +L + +HH+V DGVS I++++F Y Sbjct: 3681 EAGATLQQFVRPFDLGVAPLLRVGLIRIAHERHLLLFDMHHIVSDGVSMNILIEEFLRFY 3740 Query: 3240 LSLDNGEEAGLIEKSDSYQKWAEALEVYANSPKLLQELAYWTDVNRIAVPAL 3291 EE E Y +A + S +L + AYW D R ++P L Sbjct: 3741 -----QEEDVFPELQIQYTDYAVWQQEQLGSERLKAQEAYWLDAFRGSLPVL 3787 Score = 147 bits (371), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 116/452 (25%), Positives = 210/452 (46%), Gaps = 42/452 (9%) Query: 1310 GYQP---KPLPSGPARESLTRAPQVLKLTEEQQQISLVIHSNDTHGVVHHETVG-LYLRG 1365 GY P + +P+ ARE L+ Q++ L I S G + + G L + G Sbjct: 3578 GYTPLNFEEIPTAGAREHY-------PLSSAQKR--LFILSQLEGGELSYNMPGILTVEG 3628 Query: 1366 ELNKAALETAYHKVLNRHESLRS---TISADGNEQIVASHANADIFFADILADYSALGDE 1422 L++ LE A+ ++++RH SLR+ T++ + +Q++ D+ F +Y+ L +E Sbjct: 3629 ALDRERLEQAFRRLIHRHGSLRTRFVTVNGEPVQQLLT-----DVPFT---VEYAELSEE 3680 Query: 1423 AINQALLKENAAAFDSVMGPLIRLRVLATARHEYLLALSAHHIIADGWSLIVFLQELAAL 1482 A L++ FD + PL+R+ ++ A +LL HHI++DG S+ + ++E Sbjct: 3681 EAG-ATLQQFVRPFDLGVAPLLRVGLIRIAHERHLLLFDMHHIVSDGVSMNILIEEFLRF 3739 Query: 1483 YSTECTGTRSLLPT-PTPFSDYAIWQKRMLESQPKEKAAAYWKNKFSVQTPAFELPSFRI 1541 Y E + P ++DYA+WQ+ L S+ + AYW + F P +LP + Sbjct: 3740 YQEE-----DVFPELQIQYTDYAVWQQEQLGSERLKAQEAYWLDAFRGSLPVLDLPGDEV 3794 Query: 1542 RDAAGVRKGSRHRYVLDIPLTAKLKAVSQSMKVSLFTVLLSAYKVLLYRISNHKELVVGI 1601 R A G R + +D L+A L+ ++ +LF VLL+AY LL++ + ++++VG Sbjct: 3795 RPAVRSFAGDRIDFQIDSSLSASLQELATRTGSTLFMVLLAAYTALLHKYTGQEDVIVGS 3854 Query: 1602 PTAGQMQMGQKHLVGYCLNILPFSTTINPEMTFRXXXXXXXXXXXXXXXXQDYSYASLMK 1661 P AG+ + L+G + + T E F QDY + L++ Sbjct: 3855 PVAGRSHATLEGLIGMFVGTVALRTYPEGEKPFEAYLQEVKETALRAYENQDYPFEELVE 3914 Query: 1662 ELHSLDGSVHPPQINTMFNM------DKSLETPDFTGMDVELLQSPVSYSKYDLSMNIVE 1715 +L P +TMF + ++ +E FT D + +K+DL++ + E Sbjct: 3915 KLELQRDLSRNPLFDTMFVLQNIEQGEQEIEGLRFTPYD-----NVHPAAKFDLTLTVSE 3969 Query: 1716 LDHELMIDFEYDPNLFDTQIITGWANYFNRIL 1747 +D L EY ++ + A +F +++ Sbjct: 3970 VDGALNCTLEYATAIYKQETAERMAGHFVQLI 4001 Score = 146 bits (369), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 104/387 (26%), Positives = 181/387 (46%), Gaps = 13/387 (3%) Query: 1365 GELNKAALETAYHKVLNRHESLRSTISADGNEQIVASHANADIFFADILADYSALGDEAI 1424 G L++ LE+A+ ++ RHESLR+ E + H N + FA +Y+ E Sbjct: 1089 GPLDRTRLESAFQALIRRHESLRTGFYMQDGELVQRVHRN--VPFA---LNYTEASVEET 1143 Query: 1425 NQALLKENAAAFDSVMGPLIRLRVLATARHEYLLALSAHHIIADGWSLIVFLQELAALYS 1484 + L+ AFD PL+R+ ++ +LL HHII+DG S+ + ++EL LY Sbjct: 1144 D-TLIHNFIRAFDLSQAPLLRVSLVKLQEERHLLLFDMHHIISDGVSIQILIEELTHLYQ 1202 Query: 1485 TECTGTRSLLPTPTPFSDYAIWQKRMLESQPKEKAAAYWKNKFSVQTPAFELPSFRIRDA 1544 E L + DYA+WQ+ E+Q ++ YW F + P +LP+ R + Sbjct: 1203 GE-----QLPELHIQYKDYAVWQREQSENQWQD-LEKYWLQSFEGELPVLDLPTDFQRPS 1256 Query: 1545 AGVRKGSRHRYVLDIPLTAKLKAVSQSMKVSLFTVLLSAYKVLLYRISNHKELVVGIPTA 1604 +GSR + LD ++ ++ +L+ VLL+AY VLL++ + +++VVG P A Sbjct: 1257 VRSFEGSRIDFTLDESGNKAIQELASRTGTTLYMVLLAAYSVLLHKYTGQEDIVVGSPVA 1316 Query: 1605 GQMQMGQKHLVGYCLNILPFSTTINPEMTFRXXXXXXXXXXXXXXXXQDYSYASLMKELH 1664 G+ Q + ++G +N L + + TF+ QDY + L+++L Sbjct: 1317 GRPQAELEGIIGMFVNTLALRSYPTGDKTFQDYLLEIKETALKAFEHQDYPFEKLVEKLG 1376 Query: 1665 SLDGSVHPPQINTMFNMDKS-LETPDFTGMDVELLQSPVSYSKYDLSMNIVELDHELMID 1723 P +T+ + + E + G+ +K+DLS+N+ E +L Sbjct: 1377 VGRDVSRNPLFDTLLVLQNTEQEEQEMDGVHFTPYLMDTVTAKFDLSLNVEEKGSKLAFG 1436 Query: 1724 FEYDPNLFDTQIITGWANYFNRILLAV 1750 EY L+ + + +A + R+L AV Sbjct: 1437 LEYSTALYRRESVERFATHLLRVLHAV 1463 Score = 130 bits (326), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 108/444 (24%), Positives = 219/444 (49%), Gaps = 55/444 (12%) Query: 3580 AYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPLQIVLGSSDFHLEFE 3639 +Y+ + + G + + L +F+ ++ +++ LRT F Y + +Q V + F L + Sbjct: 1078 SYNMPGVFTVDGPLDRTRLESAFQALIRRHESLRTGF-YMQDGELVQRVHRNVPFALNYT 1136 Query: 3640 DITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVYQMLWSFHHILMDGW 3699 + + +E ++ + H + + FDL Q PL+R L+K + + +L+ HHI+ DG Sbjct: 1137 EAS-VEETDTLIH-------NFIRAFDLSQAPLLRVSLVKLQEERHLLLFDMHHIISDGV 1188 Query: 3700 CIGIVLKDMLEHYKQLNAGSRPSLETHQYRLYLDWLASKNK---EEAKVYWMQYLE---- 3752 I I+++++ Y+ P L QY+ Y W +++ ++ + YW+Q E Sbjct: 1189 SIQILIEELTHLYQ---GEQLPELHI-QYKDYAVWQREQSENQWQDLEKYWLQSFEGELP 1244 Query: 3753 ------DYKYKELLRKEGTSKEFRLAVLDIKLEEKVRTAVTHVASSSGITINSFFQAVWG 3806 D++ + EG+ +D L+E A+ +AS +G T+ A + Sbjct: 1245 VLDLPTDFQRPSVRSFEGSR-------IDFTLDESGNKAIQELASRTGTTLYMVLLAAYS 1297 Query: 3807 ILLSKYDNAEDVVFGAVISGR-SPEIEGIERMVGLFINTIPVRVRLSG-KTFHELAGEIQ 3864 +LL KY ED+V G+ ++GR E+EGI +G+F+NT+ +R +G KTF + EI+ Sbjct: 1298 VLLHKYTGQEDIVVGSPVAGRPQAELEGI---IGMFVNTLALRSYPTGDKTFQDYLLEIK 1354 Query: 3865 SSFISSEQYGYVPLSDI-------QAWSHRDLINHVMVFENYPLDREIRDTDGQQME-YG 3916 + + + ++ P + + S L + ++V +N ++E ++ DG Y Sbjct: 1355 ETALKAFEHQDYPFEKLVEKLGVGRDVSRNPLFDTLLVLQN--TEQEEQEMDGVHFTPYL 1412 Query: 3917 FQIAGCEILEHTNYDFSI-IIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTAC 3975 + +D S+ + E G + Y+ Y +E++ ++LL ++ V+ Sbjct: 1413 MDTVTAK------FDLSLNVEEKGSKLAFGLEYSTALYRRESVERFATHLLRVLHAVSVN 1466 Query: 3976 PQIEAGDVEVLSQEEKLKLMNVFN 3999 PQ++ ++E+++ EEK++++ VFN Sbjct: 1467 PQLQLAEIEMITPEEKVQIVEVFN 1490 Score = 123 bits (309), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 141/551 (25%), Positives = 244/551 (44%), Gaps = 58/551 (10%) Query: 1801 ILDKDMHPSPVGVPGEVYLA-------RLTEPSLLAEQ----PSTS------TGIMAMYT 1843 ILD+ + P+GV GE+Y+A L P L AE+ P + TG +A Sbjct: 5880 ILDEQLRLVPLGVEGEMYIAGDGVARGYLNRPDLTAEKFIRNPFAAEGNMYRTGDLARRL 5939 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKILAY- 1902 + +I+ IG + G I L I+ +L+ PL+ A V Q+ + AY Sbjct: 5940 PNGDIEYIGRIDHQVKIRGYRIELGEIEAKLLDIPLVEEALVVAWADAHGQK--SLCAYF 5997 Query: 1903 ITPRGTSIPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKALR 1962 + R S V E++ L + +P IPS F+ LD +PL G ++ + LP + Sbjct: 5998 VADREMS---VSELRNELSAGLPAYMIPSYFVQLDVMPLTPNGKLDRKALPEPNSGIKAG 6054 Query: 1963 EEIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDISL 2022 + P + E LA IW+ VL + LV +D+FFELGG+S+K S+ S + + + Sbjct: 6055 ADFTAPRTDVENILASIWQGVLGVPLVGIHDNFFELGGDSIK-SIQVSSRLLQAGYKLEM 6113 Query: 2023 RMLFEHPTVKGLAKAINGAGKSFLPEITPLGKKDWYPQ-SSSQKRLFAIEQMGGAGTAYN 2081 + LF +PT+ LA+ + S + I + + S +Q R F + M +N Sbjct: 6114 KDLFGYPTIAELAQRV-----SVVSRIADQSEVHGSVRLSPAQHRFFDEQSMDLH--HFN 6166 Query: 2082 ITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFELLHDEPVQVIHDDIPFSISYSIA-- 2139 + +L+ + + E +++ + H+ LR F ++ ++ + + YS+ Sbjct: 6167 QSVMLYRRDGFNTDALAEVVRKIAEHHDALRLVFR-QGEQGLEAWNRSMGEGELYSLQIH 6225 Query: 2140 --EDEDEP--------ELVKRFILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGI 2189 DE +P E ++R I SL PLFR+ + ++ EH++I+ +HH+ DG+ Sbjct: 6226 DLRDETDPASAIEAGAEAIQRSI---SLEDGPLFRLGLFRCAEGEHLLIV-IHHLAVDGV 6281 Query: 2190 SANILCNDLISLYS----GE--NLPGLEVQYKDYTALHNEMLSNERIRQQGEYWQQLLSD 2243 S IL DL Y GE P Y+ + + ++ Q+ YW ++ D Sbjct: 6282 SWRILFEDLQEGYEQAARGEAVKFPQKTDSYRAWVEGITQFANSPAAEQERSYWAEVEGD 6341 Query: 2244 DIPSLTLPLDFPRPPVQSFDGACYSVTLDSDLTRGLKVLSNR-LKTTLYTLLLASYNILL 2302 + LP D + D +V + T +NR T + LLL + + + Sbjct: 6342 GF--VPLPKDKVDGALLIKDSEAVTVRWSPEETEQFLKEANRTYNTEVNDLLLTALGMAV 6399 Query: 2303 SKYSNQEDIVI 2313 +++ E + I Sbjct: 6400 HEWTGIERVGI 6410 Score = 104 bits (259), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 77/255 (30%), Positives = 119/255 (46%), Gaps = 21/255 (8%) Query: 1801 ILDKDMHPSPVGVPGEVYLA-------RLTEPSLLAEQ-------PSTS---TGIMAMYT 1843 ++D SPVGVPGE+ +A +P L AE+ P TG +A + Sbjct: 7400 MMDSASQVSPVGVPGELCIAGEGVARGYFNQPDLTAEKFIPHPYKPGERIYRTGDLARWV 7459 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKILAYI 1903 D I+ +G + G I L ++ Q++ P + A V T Q ++ Sbjct: 7460 PDGNIEYLGRIDHQVKIRGYRIELGEVEAQILKVPSVQEAVVLALADST-GSTQLCAYFV 7518 Query: 1904 TPRGTSIPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKALRE 1963 G + +RE L S +P IP+AF+ L ++PLN G ++ + LPA + Sbjct: 7519 AEEGLAAGVLREA---LASELPSYMIPTAFVQLAQMPLNPNGKLDRKALPAPETLLRSTA 7575 Query: 1964 EIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDISLR 2023 E + P +TE LA+IW VL ++ + D FFELGG+SLK L I + L+ Sbjct: 7576 EYIAPRTQTEVELAQIWSEVLGVQEIGIRDHFFELGGHSLKVLGLIQRISSGMGVQLPLQ 7635 Query: 2024 MLFEHPTVKGLAKAI 2038 ++F PTV+ +A I Sbjct: 7636 VVFNLPTVEEMAHEI 7650 Score = 94.0 bits (232), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 78/310 (25%), Positives = 139/310 (44%), Gaps = 36/310 (11%) Query: 1333 KLTEEQQQISLVIHSN-DTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRSTIS 1391 KLT Q+ ++ HS + H V+ E ++G + + ++ RH LR+ Sbjct: 6615 KLTPMQK--GMLFHSLLEPHSEVYFEQAKFEIQGAFYPEDFKRSLKYLMKRHAILRTNFH 6672 Query: 1392 ADGNE---QIVASHANADIFFADI-----------LADYSALGDEAINQALLKENAAAFD 1437 A + QIV D + D+ LA Y+A ++ A F+ Sbjct: 6673 AGWGDFPIQIVFKERACDFVYEDLHELEADEIQARLAAYTA-----------QDKARGFN 6721 Query: 1438 SVMGPLIRLRVLATARHEYLLALSAHHIIADGWSLIVFLQELAALYSTECTGTRSLLPTP 1497 L+R+ +L TA Y L S+HHII DGW + + LQE+ Y LP Sbjct: 6722 LAEEALLRVAILRTAEEAYHLLWSSHHIILDGWCMPLVLQEVFETYGALREQREPELPAA 6781 Query: 1498 TPFSDYAIWQKRMLESQPKEKAAAYWKNKFSVQTPAFELPSFRIRDAAGVRKGSRHR--Y 1555 +S Y W LE Q +E+A++YW+ +LP + +A + + Sbjct: 6782 VSYSQYIQW----LEKQGEEEASSYWRGYLEGYEQQTKLPQAITQPSAKAEAYVSEKLVF 6837 Query: 1556 VLDIPLTAKLKAVSQSMKVSLFTVLLSAYKVLLYRISNHKELVVGIPTAGQMQM--GQKH 1613 LD LT +L+ V++ +V++ T++ +A+ ++L R + +++V G +G+ G + Sbjct: 6838 TLDAELTDRLEQVAKQHQVTMNTLMQAAWGIVLQRYNRSQDVVFGSVVSGRPAEIPGIES 6897 Query: 1614 LVGYCLNILP 1623 ++G +N +P Sbjct: 6898 MIGLFINTVP 6907 Score = 84.0 bits (206), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 71/296 (23%), Positives = 122/296 (41%), Gaps = 19/296 (6%) Query: 1349 DTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRSTI-SADGNE--QIVASHANA 1405 + H + E +G + A + V+ RH LR+ S G+E Q+V H A Sbjct: 2571 EPHTGAYFEQAAFDFKGSFDPTAFGHSLDAVVERHAILRTNFYSGWGSEPLQVVFRHRGA 2630 Query: 1406 DIFFADILADYSALGDEAINQALLKENAAAFDSVMGPLIRLRVLATARHEYLLALSAHHI 1465 + + D+ ++ + + K+ A F+ L+R+ +L T + L S HHI Sbjct: 2631 KLVYEDLREMNASQREAYLKTFGAKDKALGFNLAEDELLRVSILQTDEESFRLLWSFHHI 2690 Query: 1466 IADGWSLIVFLQELAALYSTECTGTRSLLPTPTPFSDYAIWQKRMLESQPKEKAAAYWKN 1525 + DGW + + QE+ Y G L P+S Y W LE Q + A+ YW Sbjct: 2691 VMDGWCVPLITQEVFEHYFALLEGREPQLAEVHPYSRYIEW----LEQQDEAVASNYWSR 2746 Query: 1526 KFSVQTPAFELPSFRIRDAAGVRKG-----SRHRYVLDIPLTAKLKAVSQSMKVSLFTVL 1580 + LP G KG + Y L LT +L+ V++ V++ +L Sbjct: 2747 YLAGYEQQTLLPQ-----VGGASKGEGYIAEKLNYPLSRELTERLEKVARDAHVTMNILL 2801 Query: 1581 LSAYKVLLYRISNHKELVVGIPTAGQMQM--GQKHLVGYCLNILPFSTTINPEMTF 1634 S + + L R + +++V G +G+ G ++G +N +P + F Sbjct: 2802 QSLWGIALQRYNGSRDVVYGSVVSGRPAEIPGIDRMIGLFINTIPVRVKTEENLPF 2857 Score = 81.6 bits (200), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 79/313 (25%), Positives = 139/313 (44%), Gaps = 17/313 (5%) Query: 1331 VLKLTEEQQQISLVIHSN-DTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRST 1389 V KLT Q+ ++ HS + + E LRG + ++ + RH LR+ Sbjct: 5100 VYKLTAMQK--GMLFHSLLEPDSSSYFEQATFELRGSFDVDIFFESFQALAQRHAILRTG 5157 Query: 1390 IS---ADGNEQIVASHANADIFFADILADYSALGDEAINQALLKEN-AAAFDSVMGPLIR 1445 AD Q+ + + D L D S EA +A + E+ F PL+R Sbjct: 5158 FYNNIADVPLQVAFKQRLIPLHYVD-LRDASMQEQEARIKAYIAEDMVKGFSLSEDPLMR 5216 Query: 1446 LRVLATARHEYLLALSAHHIIADGWSLIVFLQELAALYSTECTGTRSLLPTPTPFSDYAI 1505 + VL + L+ S HHI+ DGW + + QEL YS + + +LP P+S Y Sbjct: 5217 VTVLQKDQ-SCLVLWSFHHIVMDGWCIPIITQELFDYYSAKKQQIQPVLPPAQPYSRYIE 5275 Query: 1506 WQKRMLESQPKEKAAAYWKNKFSVQTPAFELPSFRIRDAAGVRKGSRHRYVLDI--PLTA 1563 W L++Q +++A+ YW LP + + A +VL + LT Sbjct: 5276 W----LDAQDEQEASTYWSQYLEDYDGNTVLPEGKTKSQAKEAGYVLKEHVLHLGASLTG 5331 Query: 1564 KLKAVSQSMKVSLFTVLLSAYKVLLYRISNHKELVVGIPTAGQMQ--MGQKHLVGYCLNI 1621 K+ V++ V++ T++ +A+ ++L R + ++V G +G+ G +++VG +N Sbjct: 5332 KMDVVAKRNHVTVNTLMQTAWGLILQRYNASSDVVFGGVVSGRPAEIAGIENMVGLFINT 5391 Query: 1622 LPFSTTINPEMTF 1634 +P + + F Sbjct: 5392 VPIRVQSSKDEAF 5404 Score = 81.3 bits (199), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 80/379 (21%), Positives = 169/379 (44%), Gaps = 19/379 (5%) Query: 1363 LRGELNKAALETAYHKVLNRHESLRSTI-SADG-NEQIVASHANADIFFADILADYSALG 1420 ++G +N AA + + ++ ++++ R I S DG +Q V + + D L+ Y ++ Sbjct: 37 MKGHINIAAFMQSINLIIKQYDAFRIRITSVDGLPQQYVVPYEERQLECLD-LSHYESVS 95 Query: 1421 DEAINQALLKENAAAFDSVM-GPLIRLRVLATARHEYLLALSAHHIIADGWSLIVFLQEL 1479 + +ALL+++ + ++ L + ++ + EY + + HHII+DG S++V+ +L Sbjct: 96 E---VEALLEQHKSKPLPLLDSELFQFLIVKISEEEYWINIKMHHIISDGISMVVYGNKL 152 Query: 1480 AALYSTECTGTRSLLPTPTPFSDYAIWQKRMLESQPKEKAAAYWKNKFSVQTPAFELPSF 1539 Y G L + Y + S +K AYW +KFS P EL + Sbjct: 153 TEFYMELIQGNEPQLGEDCSYIQYISDENAYELSDRYQKDKAYWLDKFS-DLP--ELTGW 209 Query: 1540 RIRDAAGVRKGS-RHRYVLDIPLTAKLKAVSQSMKVSLFTVLLSAYKVLLYRISNHKELV 1598 + + + + R + + L +L+A Q ++SLF + A + +++++N ++V Sbjct: 210 KSYNPLSLSTHAVREHFTVPEVLYHELQAFCQQNRISLFQFFMGAMYIYIHKMTNQPDVV 269 Query: 1599 VGIPTAGQMQMGQKHLVGYCLNILPFSTTINPEMTFRXXXXXXXXXXXXXXXXQDYSYAS 1658 +G A + +K +G ++ T + +M Q Y Y Sbjct: 270 IGTSFANRGNKKEKQKIGMFVSTAAARTYVKKDMDVLSFLQDVARDQMSVLRHQKYPYNQ 329 Query: 1659 LMKELHSLDGSVHPPQINTMFNMDKSLETPDFTGMDVELLQSPVSYSK---YDLSMNIVE 1715 L+++L + G+ I +F + ++ +D + + + D ++IVE Sbjct: 330 LIQDLREMHGN---KDIQRLFGVSMEYRLINWVDLDDVRILTDYDFCGDEVNDFVLHIVE 386 Query: 1716 L--DHELMIDFEYDPNLFD 1732 + + EL++D +Y LF+ Sbjct: 387 ILDEGELVLDVDYRTELFE 405 Score = 79.7 bits (195), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 100/455 (21%), Positives = 190/455 (41%), Gaps = 31/455 (6%) Query: 3558 VYTMTPMQESMLFHALKNKRSDAYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFV 3617 +Y +T Q+ + + L + +KG I +S LI+ +YD R R Sbjct: 6 LYDLTNAQKRIWYTELLYPDTSVSQLSGTAKMKGHINIAAFMQSINLIIKQYDAFRIRIT 65 Query: 3618 YKKLHRPLQIVLGSSDFHLEFEDITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAIL 3677 P Q V+ + LE D++H ES ++ +E L + K L+ L + ++ Sbjct: 66 SVD-GLPQQYVVPYEERQLECLDLSHYES---VSEVEALLEQHKSKPLPLLDSELFQFLI 121 Query: 3678 LKTGDSVYQMLWSFHHILMDGWCIGIVLKDMLEHYKQLNAGSRPSL-ETHQYRLYLD--- 3733 +K + Y + HHI+ DG + + + E Y +L G+ P L E Y Y+ Sbjct: 122 VKISEEEYWINIKMHHIISDGISMVVYGNKLTEFYMELIQGNEPQLGEDCSYIQYISDEN 181 Query: 3734 -WLASKNKEEAKVYWMQYLEDYKYKELLRKEG--TSKEFRLAVLDIKLEEKVRTAVTH-- 3788 + S ++ K YW+ K+ +L G + L+ ++ V + H Sbjct: 182 AYELSDRYQKDKAYWLD-----KFSDLPELTGWKSYNPLSLSTHAVREHFTVPEVLYHEL 236 Query: 3789 --VASSSGITINSFFQAVWGILLSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINTIP 3846 + I++ FF I + K N DVV G + R + E ++ +G+F++T Sbjct: 237 QAFCQQNRISLFQFFMGAMYIYIHKMTNQPDVVIGTSFANRGNKKE--KQKIGMFVSTAA 294 Query: 3847 VRVRLSGK----TFHELAGEIQSSFISSEQYGYVPL-SDIQAW-SHRDLINHVMVFENYP 3900 R + +F + Q S + ++Y Y L D++ ++D+ V Y Sbjct: 295 ARTYVKKDMDVLSFLQDVARDQMSVLRHQKYPYNQLIQDLREMHGNKDIQRLFGVSMEYR 354 Query: 3901 LDREIRDTDGQQMEYGFQIAGCEILEHTNYDFSIIIEPGEDFIIRIVYNALAYDKETISI 3960 L + D D ++ + G E+ + + I+ E GE ++ + Y +++ + Sbjct: 355 LINWV-DLDDVRILTDYDFCGDEVNDFVLHIVEILDE-GE-LVLDVDYRTELFERSEVKD 411 Query: 3961 LESYLLAIIGQVTACPQIEAGDVEVLSQEEKLKLM 3995 + S LL I Q+ PQ+ +V +L + E+ ++ Sbjct: 412 MVSQLLTIAEQIIHSPQLSIAEVNLLGEPEEQSIL 446 >C3HA00.1 C3HA00_BACTU Phenylalanine racemase Length = 6350 Score = 1585 bits (4104), Expect = 0.0, Method: Compositional matrix adjust. Identities = 858/2238 (38%), Positives = 1331/2238 (59%), Gaps = 61/2238 (2%) Query: 1798 IFVILDKDMHPSPVGVPGEVYLA------------RLT------EPSLLAEQPSTSTGIM 1839 +FV+ DK+ + P+GVPGE+ ++ RLT P +L E+ TG + Sbjct: 767 VFVV-DKNSNLLPLGVPGELCISGDGLSKGYLNNERLTVQRFVPNPFILGER-MYRTGDL 824 Query: 1840 AMYTADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKI 1899 D I+ +G + G I L I+ QL+ H + A V + + Q + Sbjct: 825 VRMLPDGNIEFLGRIDHQVKIRGFRIELGEIESQLLKHKEVKEAVVIAREDNSHH--QYL 882 Query: 1900 LAYITPRGTSIP-KVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDED 1958 AY T + +V+EI+KFL +P IP+ F+ LD++PL + G ++ + LP+ DE Sbjct: 883 CAYFTSESSKGEIRVQEIRKFLAKELPEYMIPAFFVQLDKLPLTTNGKVDRKALPSPDES 942 Query: 1959 K-ALREEIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFS 2017 A E P N EE+L IW+++L++E + +FFE+GG+SLKA+ + I KE Sbjct: 943 SVAGVVEYEAPRNTVEEKLVSIWQDILDIENIGIQHNFFEIGGHSLKATTMVSRIHKELM 1002 Query: 2018 TDISLRMLFEHPTVKGLAKAINGAGKSFLPEITPLGKKDWYPQSSSQKRLFAIEQMGGAG 2077 ++ LR +F+ PT+KG+ + I+ +S I + ++D+YP SS+Q+RL+ + ++ G+G Sbjct: 1003 VELPLRQIFQTPTIKGIGEYIDSTKESVYASIKKVEEQDYYPLSSAQRRLYILNKIEGSG 1062 Query: 2078 TAYNITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFELLHDEPVQVIHDDIPFSISYS 2137 +YN+ + ++G LD ++E F +L++RHE LRTSF ++ EPVQ I +I F ++Y Sbjct: 1063 VSYNMPFAMKIKGDLDVHQLENTFYKLIERHEALRTSFVMVDGEPVQKIEKEIDFQVTYR 1122 Query: 2138 IAEDEDEPELVKRFILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGISANILCND 2197 E++ F+ PF L + PL RV I+ +D EH++++DMHHII+DG+S NIL + Sbjct: 1123 EMGTNKLDEMINGFVKPFDLEKGPLLRVEIIHVTDDEHVMVLDMHHIISDGVSMNILNRE 1182 Query: 2198 LISLYSGENLPGLEVQYKDYTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRP 2257 L LY G+ L L++QYKDY ++ + E +++Q EYW + +++P L +P D+ RP Sbjct: 1183 LCKLYEGKELSPLDLQYKDYAVWQKDLFTQEEMKKQEEYWINVFKEEVPILNMPTDYKRP 1242 Query: 2258 PVQSFDGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPV 2317 P QS +GA S +DS+LT+ L ++ T+Y LLLA Y LLS+Y+ Q+DIV+GSP+ Sbjct: 1243 PTQSVEGARRSFEIDSELTKNLNRIAKENGVTMYMLLLAGYTTLLSRYTGQDDIVVGSPI 1302 Query: 2318 AGRFNYSTNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQDYPFEELISKL 2377 AGR ++ N+VGMFVNTLAMRN P + KTF+ +L EVKEN L+A+ENQDYP +EL+ KL Sbjct: 1303 AGRSHHDFENIVGMFVNTLAMRNYPNEDKTFRNYLREVKENALKAYENQDYPLDELVEKL 1362 Query: 2378 GIERDISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYEFKNDVAKFDLILEVIENTENL 2437 ++RD+SR+ +FD MFVLQ+LD + ++ + Y+ + ++A FDL L +E + Sbjct: 1363 DLQRDMSRSALFDTMFVLQNLDTSNEEIK--GLSFETYDSELNIANFDLTLSAVETNNII 1420 Query: 2438 TLNFEYCAKLFQESTIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTA 2497 + EYC KLF++ TI ++SE F+ IL + N V L ID+L EE L+ FN+T Sbjct: 1421 KFDLEYCTKLFKKETIAKISEHFVSILREITNNQEVCLGQIDMLSGEEKHILLNEFNETY 1480 Query: 2498 TAYPGGKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTV 2557 YP KT+YQLFEEQ RTP VA+ +G+ +TY+ N K+NQ+AR+L KGV P+ V Sbjct: 1481 MDYPKNKTIYQLFEEQVERTPNKVAVEFEGQQVTYKELNEKSNQVARVLYDKGVHPEMIV 1540 Query: 2558 GILMEHSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQF 2617 GI++E S ++I+ + ++K+G AY+PIDP YP ERI ++++DSN + +LT L +K F Sbjct: 1541 GIMVERSLDMIVGIMGILKSGAAYLPIDPEYPEERIKYMVEDSNAKFVLTQTHLYDKLHF 1600 Query: 2618 -QGEFIDAASSKWYCGDDSNPVSV---NSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYV 2673 E I S + +++ N+ +DLAY+IYTSGSTGLPKGV+ H L N Sbjct: 1601 INNECITKISINDETIKNQEQINMERRNNRNDLAYVIYTSGSTGLPKGVLVEHHSLVNLC 1660 Query: 2674 WWGDKTYVHGEAVDFPLYSSIAFDLSVTLIYIPLISGNKVFIYSGVSYESLLEAVVIDNQ 2733 W + E Y ++FD S+ I+ LI+G + + L + N Sbjct: 1661 NWYVDFHKITERDRITNYLKVSFDASIGEIFPCLITGATLHVLGKDMRLDLDKLNEYMNS 1720 Query: 2734 VDFIMLT-PSHLKILGEYDLS-RLKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGP 2791 D + T PS K+ ++ L +R + GGE K ++ N YGP Sbjct: 1721 KDITVATFPS--KVSEQFILQDNHSLRMLVSGGE--------KLILNKNTRYQLVNAYGP 1770 Query: 2792 TETTVACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSR 2851 TE TV T + + D +PIG P++N ++Y+V++ +L IG+ GELCI+G G++R Sbjct: 1771 TENTVVTTSFLMNKNDD---NIPIGKPVYNTKVYIVNKYNQLCPIGVTGELCISGVGLAR 1827 Query: 2852 GYLNREELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGE 2911 GYLN LT EKFV +PF + MYRTGDLVR + DGNVEF+GR+D QVKIRG+RIELGE Sbjct: 1828 GYLNNPALTAEKFVGNPFVSGEKMYRTGDLVRWMPDGNVEFIGRIDHQVKIRGYRIELGE 1887 Query: 2912 IENQLVKQPGVNKAAVIISTGPTDSRYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFF 2971 IE+QL+K + + V+ + Y+ AY ++ ++ P +M+PS+F Sbjct: 1888 IESQLLKHQDIKEVVVVAKEDKKNHTYISAYIVSEKAISSAKIREFLEKELPDYMIPSYF 1947 Query: 2972 VQMKSIPLTASGKVDRKKLPDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSN 3031 VQ+ +PLT++ KVDRK LP+ S Q Y AP+N +E L +W ++LGI +G ++ Sbjct: 1948 VQLDQLPLTSNDKVDRKALPEPDRSSQSGVEYEAPRNEVETHLVEIWRDILGIEDIGINH 2007 Query: 3032 SFIKLGGDSIKAIQIVSRLKKYGLSLEVKELFLHQNIKGISPFVKQNIKRHN-QGTIEGP 3090 F GGDSIKA+QIVSRL + L LEVK+LF + IK +S +VK+ KR + G Sbjct: 2008 HFFVSGGDSIKALQIVSRLSRINLKLEVKDLFANPKIKDLSKYVKKQNKRLKPYEIVTGE 2067 Query: 3091 VKLTAIQKWFFEQNFAEMHHWNQSILLHNER-FDVQFIRQAFQRITEHHDALRMVYRHTG 3149 V L+ IQKW+FE+N E+ H+NQS +L E FD + I + F +I E HDALRM+YR Sbjct: 2068 VILSPIQKWYFEKNKEELDHFNQSFMLFREDGFDQKRIERVFNKILEQHDALRMIYRE-N 2126 Query: 3150 QAGVEQSNRGLAGELFSLEVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTT 3209 + Q NRG LF L V D+ G ++ + ++ IQK ++ G L+ L L++T Sbjct: 2127 DGEIIQYNRGYKDNLFDLYVHDVEGVENKEEKIYELATNIQKKSSIKNGKLVNLCLFKTN 2186 Query: 3210 NGDYLAIVIHHLVVDGVSWRIILDDFASCYLSLDNGEEAGLIEKSDSYQKWAEALEVYAN 3269 GD+L I IHHLVVDGVSWRIIL+DF + Y GE+ + K++S+++++ L YA+ Sbjct: 2187 QGDHLLITIHHLVVDGVSWRIILEDFETLYSQDLRGEKLDVGFKTESFKEFSSKLREYAS 2246 Query: 3270 SPKLLQELAYWTDVNRIAVPALPKDSEAGNGKIKDRYQTKTVLSEKETTNLLRHAGDAYQ 3329 + KLL+E YW ++ V +P+ E + ++ L++++T +LLR + AY Sbjct: 2247 NNKLLKEKEYWQEIANTEVAFIPRKKELKSDTFENSKTVSISLNKEKTISLLRKSNRAYN 2306 Query: 3330 TETXXXXXXXXXXXIKGWANVDRVRINMEGHGREALIQDLDITRTVGWFTSTYPLVLELA 3389 TE + + + ++INMEGHGRE +++++DI+RTVGWFT+ YP++++L Sbjct: 2307 TEINDILLTSLLLGAREITSENCIKINMEGHGREDILENVDISRTVGWFTTMYPVLIDLG 2366 Query: 3390 NSHELPLHIMTTKETIRQTPNKGMGYQVLKYLTSPELRAAVDFNVMPEISFNYLGQFGNE 3449 N +L +I KET+R+ PNKG+G+ +LKYL+ + ++ P ISFNYLG+ N+ Sbjct: 2367 NETDLATNIKMVKETLRKIPNKGIGFGILKYLSKE--KYLLNEQKAP-ISFNYLGEMDND 2423 Query: 3450 ASYGTFEICNTFMESTESPESHRPYAIDINAMIVGNRVEIRVDYNPGQFNEATMSRFAEL 3509 + F T + R +I+IN++I+ N + I +N +F+E T+ + + Sbjct: 2424 VNRNEFSESKFSYGETIGGKISRNNSIEINSIIINNELVINTTFNELEFDELTIRKLNDK 2483 Query: 3510 LLNSLKLIISHCTREERIQRSPSDLTYKKLTFEELDDLNRLYPG-GITDVYTMTPMQESM 3568 SL+ II HC + ++++P D KLT EL D+ Y I +Y + MQ+ M Sbjct: 2484 FKESLETIIDHCVSQIEVEKTPYDYGDTKLTLSELKDIKEKYKDFEIEKIYPLANMQKGM 2543 Query: 3569 LFHALKNKRSDAYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPLQIV 3628 LFHAL+NK S AY EQ ++D+ G + E+L SF I+ +Y+ILR F Y+ + P QI+ Sbjct: 2544 LFHALENKNSKAYFEQTVMDITGYVDVEILKTSFNKIMQRYEILRASFEYEIVGEPRQII 2603 Query: 3629 LGSSDFHLEFEDITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVYQML 3688 + + +++ DI+ + EK ++ + D EK F+L + LMR L++T +++Y+++ Sbjct: 2604 IADREIGVQYCDISERGTIEKELFIKNYREEDTEKGFNLSKDTLMRVCLIRTDENLYKLV 2663 Query: 3689 WSFHHILMDGWCIGIVLKDMLEHYKQLNAGSRPSL-ETHQYRLYLDWLASKNKEEAKVYW 3747 WS HHIL+DGWC+GIVL ++ Y +L G L ET Y Y+ WL ++KEE K YW Sbjct: 2664 WSHHHILLDGWCLGIVLGELFTVYGKLINGEEYELEETKPYSDYIKWLEEQDKEEGKSYW 2723 Query: 3748 MQYLEDYKYKELLRKEGTSK---EFRLAVLDIKLEEKVRTAVTHVASSSGITINSFFQAV 3804 QYL+ Y+ K + K +K E+ I+ ++ +T +A+ + +T N+ FQ++ Sbjct: 2724 EQYLDGYEEKAQIPKLQITKNNSEYLRREKVIEFSNELTNKITQLANRNSVTFNTVFQSI 2783 Query: 3805 WGILLSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRL-SGKTFHELAGEI 3863 WGI+L+KY+N ++VVFG ++SGR ++GIE+M+GLFIN IP R+ L + F E+ + Sbjct: 2784 WGIILAKYNNTDEVVFGTIVSGREAPVDGIEKMIGLFINAIPTRINLGKNQKFKEVLTVV 2843 Query: 3864 QSSFISSEQYGYVPLSDIQAWS--HRDLINHVMVFENYPLDREIRDTDGQQMEYGFQIAG 3921 QS I+S Y Y+ L+++QA S DLI+H++VFENY +D+ I ++M+ GF++ Sbjct: 2844 QSEAIASNNYNYMNLAEVQAMSKLKNDLIDHIIVFENYAVDKRI--AGNEKMDIGFEVED 2901 Query: 3922 CEILEHTNYDFSIIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTACPQIEAG 3981 E +NY FSI PGE + + Y+ YD + I +E ++ + QV A + Sbjct: 2902 IHAEEQSNYSFSIAATPGEQLNLVLTYDGNIYDDKIIDNIEMHIKKVTEQVIADENKKIN 2961 Query: 3982 DVEVLSQEEKLKLMNVFN 3999 +++++++EE+ L+ FN Sbjct: 2962 EIDIIAEEERTTLLYEFN 2979 Score = 1535 bits (3974), Expect = 0.0, Method: Compositional matrix adjust. Identities = 859/2244 (38%), Positives = 1303/2244 (58%), Gaps = 65/2244 (2%) Query: 1801 ILDKDMHPSPVGVPGEVY-----LAR--LTEPSLLAEQ--PST--------STGIMAMYT 1843 ILD + + P+GV GE+ LAR L P L AE+ P+ TG +A Sbjct: 3307 ILDMENNLVPLGVAGELCVSGEGLARGYLNRPELTAEKFVPNPFIPGERMYRTGDLARLL 3366 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKILAYI 1903 + I+ +G + G I L ++ QL I A V + Q + AY Sbjct: 3367 PNGNIEFLGRIDHQVKIRGFRIELGEVENQLFKQKEIKEAVVIAREDNNGQ--PYLCAYF 3424 Query: 1904 TPRGTSI-PKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKALR 1962 T K++EI+K L +P IP+ F+ LD++PL + G ++ + LP DE + Sbjct: 3425 TSETRKKESKLQEIRKDLAQELPEYMIPAFFVQLDKLPLTANGKVDRKALPEPDESAVVG 3484 Query: 1963 EEIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDISL 2022 E P NE EERL IW+ +L +E + N FFE+GG+SLKA+ + I KE +I L Sbjct: 3485 VEYEAPRNEVEERLVSIWQEILGVEKIGINQHFFEIGGHSLKATTMVSKIHKELMVEIPL 3544 Query: 2023 RMLFEHPTVKGLAKAINGAGKSFLPEITPLGKKDWYPQSSSQKRLFAIEQMGGAGTAYNI 2082 R +F+ PT+KG+ + I+ +S I + ++D+YP SS+QKRL+ + ++ G G +YNI Sbjct: 3545 RQIFQTPTIKGIGEFIDSTKESVYASIKKVEEQDYYPLSSAQKRLYILNKIEGNGVSYNI 3604 Query: 2083 TGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFELLHDEPVQVIHDDIPFSISYSIAEDE 2142 + ++G LD ++E+AF +L++RHE LRTSF ++ EPVQ I DI F ++Y Sbjct: 3605 PFAMKIKGDLDVQQLEKAFHKLIERHEALRTSFVMVDGEPVQKIEKDIDFQVTYREMGTN 3664 Query: 2143 DEPELVKRFILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGISANILCNDLISLY 2202 +++ F+ PF L +APL RV I+ +D EH++++DMHHII+DG+S I +L LY Sbjct: 3665 KLDDIINGFVKPFDLEKAPLLRVEIIHVTDDEHVIVLDMHHIISDGVSMGIFTQELAELY 3724 Query: 2203 SGENLPGLEVQYKDYTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQSF 2262 +G+ L L +QYKDY+ E+ + E +++Q EYW + +++P L +P D+ RPP+QS Sbjct: 3725 NGKELSPLSIQYKDYSVWQRELFTQEEMKKQEEYWMHVFKEEVPVLNMPTDYKRPPIQST 3784 Query: 2263 DGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRFN 2322 +G +DSD+ LK ++ TLY LLLA Y LLSKY+ QE+IV+GSP+AGR + Sbjct: 3785 EGDLVHFEIDSDIYVNLKKMAKEHGVTLYMLLLAGYTTLLSKYTGQEEIVVGSPIAGRPH 3844 Query: 2323 YSTNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIERD 2382 ++G+FVNTLAMRN P + +FQ++L EVK+N L+A+ENQDYPF+EL+ KL ++RD Sbjct: 3845 DDLKQIMGIFVNTLAMRNYPKRDVSFQDYLKEVKDNALKAYENQDYPFDELVEKLDLKRD 3904 Query: 2383 ISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYEFKNDVAKFDLILEVIENTENLTLNFE 2442 +SR+ +FD M VLQ+ D D + + + Y+ K V+KFDL L +E ++ Sbjct: 3905 MSRSALFDTMLVLQNFDY--DDFEIQGLTFSPYQMKAHVSKFDLTLTAVEEERSIKCVLN 3962 Query: 2443 YCAKLFQESTIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYPG 2502 Y KLF++ T+ R+++ +++ ++E + DI LL +EE L+ DT YP Sbjct: 3963 YRTKLFKKETVERLAKHLIQVFKEIIEKPEQSIQDIMLLSEEEVQMLLQDDKDTKADYPK 4022 Query: 2503 GKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILME 2562 KT+ QLFEEQ RTP VA+V + + +TY N + NQMAR+L+ KG KP TVG+L+E Sbjct: 4023 DKTISQLFEEQVKRTPHHVAVVFKNQKLTYLELNERANQMARLLQEKGAKPGITVGMLVE 4082 Query: 2563 HSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEFI 2622 S E+II + AV+KAG Y+PIDP +R N I+KDSN +++ E QF E I Sbjct: 4083 ESLEMIIGIMAVLKAGATYLPIDPEQLDKRTNVILKDSNASLLIVKGERKETLQFNAEVI 4142 Query: 2623 DAASSKWYCGDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYVH 2682 D SN + + AYIIYTSGSTG PKGV +H + NY+ W K Sbjct: 4143 SMEDDSIKERDTSNLLVNYKWNHNAYIIYTSGSTGTPKGVCVQHNNVVNYMTWFTKEANL 4202 Query: 2683 GEAVDFPLYSSIAFDLSVTLIYIPLISGNKVFIYSGVSYESLLEAV-VIDNQ-VDFIMLT 2740 E L SS AFDL T +Y L++G ++ + + Y + +A+ I+ Q + ++ LT Sbjct: 4203 KETDKAMLVSSYAFDLGYTSLYSSLLNGCELHLVTKEVYTNAQKALQYIEEQGISYLKLT 4262 Query: 2741 PSHLKILGE-----YDLSRLKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETT 2795 PS +L + S +R ++GGE +P + F++ V N YGPTE T Sbjct: 4263 PSLFNVLVNDPSFSNNQSCKTLRLVVLGGEKINPIDVETFYTHYPNHA-VMNHYGPTEAT 4321 Query: 2796 VACTF--YRYYPDKDLRNPVPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGY 2853 + + Y + IG PI N++ YVVDQ KL G+ GELC++GDGV+ GY Sbjct: 4322 IGSVYQVIEYDTMAAFKECPVIGRPIQNMKAYVVDQQMKLVPEGVYGELCLSGDGVASGY 4381 Query: 2854 LNREELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIE 2913 LNR +LT EKFV +PF+ + MYRTGDL R L DG +E GR+D QVKIRG+RIE EI+ Sbjct: 4382 LNRADLTEEKFVQNPFEPNKKMYRTGDLARRLSDGRIELAGRIDGQVKIRGYRIETEEIK 4441 Query: 2914 NQLVKQPGVNKAAVIISTGPTDSRYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFFVQ 2973 LVK + +A VI G + RYLCAY T+ ++ P +M+PS+FVQ Sbjct: 4442 RHLVKHEQIKEAFVIDREGQDERRYLCAYITSQRDLSFEELRAYLKVEIPEYMIPSYFVQ 4501 Query: 2974 MKSIPLTASGKVDRKKLPDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSF 3033 M+ IPLTA+GKVD K LP+ ++ Y P+N +EEKL VWE++LG+ +G S++F Sbjct: 4502 MERIPLTANGKVDEKALPEPDVGKGVD--YEKPRNQVEEKLVKVWEDILGVKSIGISHNF 4559 Query: 3034 IKLGGDSIKAIQIVSRLKKYGLSLEVKELFLHQNIKGISPFVKQNIKRHNQGTIE---GP 3090 GGDSIKA+QI+SRL + G++LE+K+LF + IK +S +V NI+ +G+ E G Sbjct: 4560 FASGGDSIKALQIISRLSREGITLEMKDLFTYPEIKFLSNYV--NIETIQEGSYEIETGD 4617 Query: 3091 VKLTAIQKWFFEQNFAEMHHWNQSILLH-NERFDVQFIRQAFQRITEHHDALRMVYRHTG 3149 V LT IQK +F +++H+N +++L+ + F + I++ + I HHDALRM+Y+ Sbjct: 4618 VLLTPIQKAYFMNGKEDVNHYNHAVMLYRKDGFREEMIQEVMEAIFVHHDALRMIYKEEN 4677 Query: 3150 QAGVEQSNRGLAGELFSLEVTDLTGCDDHTDLMHAGIKTI-QKGIDLEKGPLLKLGLYQT 3208 V Q NR + F V D++ +D+ D+ + TI QK ID+++GPL+ + ++T Sbjct: 4678 NE-VLQFNREVEKNQFGFYVYDVSR-EDNPDVKIQELATILQKKIDIQEGPLVNVAQFKT 4735 Query: 3209 TNGDYLAIVIHHLVVDGVSWRIILDDFASCYLSLDNGEEAGLIEKSDSYQKWAEALEVYA 3268 GD+L ++IHHLVVDG+SWR++ +DFA Y L GE K+ SY+++A L YA Sbjct: 4736 NVGDHLLLIIHHLVVDGISWRVLFEDFALGYSQLMKGEPIAFYPKTTSYKEYATQLNEYA 4795 Query: 3269 NSPKLLQELAYWTDVNRIAVPALPKDSEAGNGKIKDRYQTKTVLSEKETTNLLRHAGDAY 3328 S K+L+E YW + + V L K E G + +D T L +ET+ LLR AY Sbjct: 4796 KSAKILREKQYWVNTLKDNVNFLEKKEEVGLFRYEDSDTFSTALGIEETSRLLRETNQAY 4855 Query: 3329 QTETXXXXXXXXXXXIKGWANVDRVRINMEGHGREALIQDLDITRTVGWFTSTYPLVLEL 3388 TE + +++RIN+EGHGRE +I+++DI+RTVGWFT+ YP+ + L Sbjct: 4856 HTEINDLLISALLIATRRVTGENKIRINLEGHGREQIIKNVDISRTVGWFTTKYPVYINL 4915 Query: 3389 ANSHELPLHIMTTKETIRQTPNKGMGYQVLKYLTSPELRAAVDFNVMPEISFNYLGQFGN 3448 + +L + I T KE++R+ PNKG+GY VLK L+ +++ P I FNYLGQ Sbjct: 4916 GDEKDLSMTIKTVKESLRRIPNKGIGYGVLKQLSGDSDLWSIE---QPPILFNYLGQMDA 4972 Query: 3449 EASYGTFEICNTFMESTES--PESHRPYAIDINAMIVGNRVEIRVDYNPGQFNEATMSRF 3506 + + F ++++ + ES + R I+INA+++ ++ I YN + E + F Sbjct: 4973 DLNNTIF--SSSWISAGESIGGKHTRETPIEINAIVLDGKLTIDTTYNTKVYAEDVVVEF 5030 Query: 3507 AELLLNSLKLIISHCTREERIQRSPSDLTYKKLTFEELDDL---NRLYPGGITDVYTMTP 3563 E +L +I HC +E+ +++P D K+L+FE+L+++ NR G I +Y + Sbjct: 5031 TEAFKAALLDVIHHCISKEQAEKTPFDYGDKELSFEQLEEIKAKNRW--GEIEKIYPLAN 5088 Query: 3564 MQESMLFHALKNKRSDAYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHR 3623 MQ+ MLFHAL++ +S AY EQ ++D+KG I L ES I+ +++ILRT Y+ + Sbjct: 5089 MQQGMLFHALEDPQSGAYFEQLVIDVKGFIDVNLFEESLNDIMKRHEILRTAIEYEITEQ 5148 Query: 3624 PLQIVLGSSDFHLEFEDITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDS 3683 P +++ + DI ++ + DREK FD + L+R L++T D Sbjct: 5149 PKNVIIKGRKIGFRYRDIRQQGIDQQKESITTYIEQDREKGFDFSKDVLIRLELIQTDDK 5208 Query: 3684 VYQMLWSFHHILMDGWCIGIVLKDMLEHYKQLNAGSRPSLETHQ-YRLYLDWLASKNKEE 3742 Y ++WS HHIL DGW GI+L ++ Y G P+LE + Y Y+ WL + KEE Sbjct: 5209 AYTIIWSNHHILFDGWGRGIILGELFHIYGNKQVGQYPNLEEPRPYSDYIRWLGEQEKEE 5268 Query: 3743 AKVYWMQYLEDYKY--KELLRKEGTSKEFRLAVLDIKLEEKVRTAVTHVASSSGITINSF 3800 YW QYL Y+ K K +++E+ I+ ++ +T +A+ + +T+N+ Sbjct: 5269 GIQYWKQYLAGYQKPAKVPSFKIDSTREYHGQETLIEFSRELTKKMTELANQNNVTLNTV 5328 Query: 3801 FQAVWGILLSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRLS-GKTFHEL 3859 Q +WGI+L+KY++ +DVVFG+V+SGR ++ GIE+MVGLFIN IP R+ + K+F + Sbjct: 5329 LQTLWGIILAKYNHTDDVVFGSVVSGRDAKVAGIEKMVGLFINAIPTRINIKEQKSFKNI 5388 Query: 3860 AGEIQSSFISSEQYGYVPLSDIQAWS--HRDLINHVMVFENYPLDREIRDTDGQQMEYGF 3917 E+Q I S+ Y Y+ LSDIQ+ S RDLI+HVM+FENY LD + + + + F Sbjct: 5389 LKEVQQQAIESQAYNYMNLSDIQSLSDLKRDLIDHVMIFENYALDERLLQEEESKSSFVF 5448 Query: 3918 Q-IAGCEILEHTNYDFSIIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTACP 3976 + I G +E TNY F+I++ PGE +++I Y+ Y ++ I + ++L I+ +V Sbjct: 5449 KDIKG---IEQTNYGFTIVVVPGEQLVLKISYDGNLYSEKLIQNIANHLKNIMDEVVQDE 5505 Query: 3977 QIEAGDVEVLSQEEKLKLMNVFNK 4000 +E+LS+EEK +N FN+ Sbjct: 5506 NKNVNQLEILSKEEKHYFLNEFNE 5529 Score = 644 bits (1660), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/1077 (35%), Positives = 587/1077 (54%), Gaps = 56/1077 (5%) Query: 2058 YPQSSSQKRLFAIEQMGGAGTAYNITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFEL 2117 YP ++ Q+ + AY ++ V+G +D EE+ ++KRHE LRT+ E Sbjct: 5084 YPLANMQQGMLFHALEDPQSGAYFEQLVIDVKGFIDVNLFEESLNDIMKRHEILRTAIEY 5143 Query: 2118 -LHDEPVQVIHDDIPFSISYSIAEDE---DEPELVKRFILP-----FSLNQAPLFRVHIV 2168 + ++P VI Y + + E + +I F ++ L R+ ++ Sbjct: 5144 EITEQPKNVIIKGRKIGFRYRDIRQQGIDQQKESITTYIEQDREKGFDFSKDVLIRLELI 5203 Query: 2169 SRSDHEHIVIMDMHHIIADGISANILCNDLISLYSGENL---PGLE--VQYKDYTALHNE 2223 D + +I HHI+ DG I+ +L +Y + + P LE Y DY E Sbjct: 5204 QTDDKAYTIIWSNHHILFDGWGRGIILGELFHIYGNKQVGQYPNLEEPRPYSDYIRWLGE 5263 Query: 2224 MLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQSFDGACYSVTLDSDLTRGLKVLS 2283 E I +YW+Q L+ +P F + + G + +LT+ + L+ Sbjct: 5264 QEKEEGI----QYWKQYLAGYQKPAKVP-SFKIDSTREYHGQETLIEFSRELTKKMTELA 5318 Query: 2284 NRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRFNY--STNNMVGMFVNTLAMRNQ 2341 N+ TL T+L + I+L+KY++ +D+V GS V+GR MVG+F+N + R Sbjct: 5319 NQNNVTLNTVLQTLWGIILAKYNHTDDVVFGSVVSGRDAKVAGIEKMVGLFINAIPTRIN 5378 Query: 2342 PAKHKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIERDISRNPVFDVMFVLQSLDLA 2401 + K+F+ L EV++ +A E+Q Y + L S + D+ R+ + VM Sbjct: 5379 IKEQKSFKNILKEVQQ---QAIESQAYNYMNL-SDIQSLSDLKRDLIDHVMIF------- 5427 Query: 2402 VPDVHLDDIRLNGYEFKNDVAKFDLILEVIENT-----------ENLTLNFEYCAKLFQE 2450 + LD+ L E K+ D+ + IE T E L L Y L+ E Sbjct: 5428 -ENYALDERLLQEEESKSSFVFKDI--KGIEQTNYGFTIVVVPGEQLVLKISYDGNLYSE 5484 Query: 2451 STIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYPGGKTVYQLF 2510 I ++ I+ VV++ N ++ +++L KEE + FN+T YP KT+++LF Sbjct: 5485 KLIQNIANHLKNIMDEVVQDENKNVNQLEILSKEEKHYFLNEFNETKAEYPKEKTIHRLF 5544 Query: 2511 EEQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILMEHSFELIIS 2570 EEQ RTP VA+V + +TY+ N K+NQ+AR+L++KGV+PDT VGI++E S E+II Sbjct: 5545 EEQVERTPNKVAVVFDKQQLTYKELNEKSNQIARLLQNKGVQPDTVVGIMLERSLEMIIG 5604 Query: 2571 MFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEFIDAASSKWY 2630 + ++K+G AY+PIDP YP ERI +I++DS I+LT A + + F+D + + Sbjct: 5605 IMGILKSGAAYLPIDPEYPEERIKYIVEDSGTNIILTKGKDAVRLSKEIVFLDEEYNHYS 5664 Query: 2631 CGDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYVHGEAVDFPL 2690 N ++ ++LAY+IYTSGSTG+PKG M + +GL NY+ W +K YV GEA+DF L Sbjct: 5665 T---ENIKVTSNTNNLAYMIYTSGSTGMPKGTMLKQRGLVNYITWANKEYVKGEALDFAL 5721 Query: 2691 YSSIAFDLSVTLIYIPLISGNKVFIYSGVSYESLLEAVVIDNQVDFIMLTPSHLKILGEY 2750 YSS +FDL++T ++ PLISGNK+ IY+ E ++ + DN+V + LTPSHL+++ + Sbjct: 5722 YSSFSFDLTITSLFTPLISGNKIVIYNNDGDEPIIRKIFKDNRVGIVKLTPSHLRLIRDI 5781 Query: 2751 DLSRLKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDLR 2810 D S I++ I+GGE A++ +VE+YN YGPTETT+ C Y+Y + D Sbjct: 5782 DNSNSSIKRLIVGGEDLKTELAREILKSFNHNVEIYNEYGPTETTIGCMIYKYSLNDDKH 5841 Query: 2811 NPVPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPFQ 2870 VPIG PI NVQ+Y++D N K+ +GI GEL I+GDGV+ GYLNR ELT EKF+ +P+ Sbjct: 5842 ISVPIGKPIDNVQIYILDDNQKILPVGIEGELYISGDGVATGYLNRPELTAEKFISNPYV 5901 Query: 2871 TSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVIIS 2930 MYRTGDL R L GN+EF+GR D QVKIRG+RIELGEIENQ++K + + V+ Sbjct: 5902 PGAKMYRTGDLARWLPSGNIEFIGRTDHQVKIRGYRIELGEIENQILKLDNIKETKVVAR 5961 Query: 2931 TGPTDSRYLCAYYT---ADFPMNXXXXXXXXXXXXPRHMVPSFFVQMKSIPLTASGKVDR 2987 DS+YLCAY + + P +M+P+FF Q+K +PLT +GK+D Sbjct: 5962 IDGEDSQYLCAYVVLENKEKAITVTEMRRYLSKELPNYMIPAFFTQLKELPLTTNGKIDI 6021 Query: 2988 KKLPDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIV 3047 LP + Q Y P+N +EEK+ +WEE+L I K+G + + +G +S+ + V Sbjct: 6022 NSLPAPDGNVQYGLEYEPPRNDLEEKIVSIWEEILNIKKIGMNTNLFDIGANSLNVMTFV 6081 Query: 3048 SRL-KKYGLSLEVKELFLHQNIKGISPFV---KQNIKRHNQGTIEGPVKLTAIQKWF 3100 SR+ + + K++F ++ S F+ K+ +K + + I+ + +K F Sbjct: 6082 SRIVAELNFRVPFKDVFDKPTVRSFSAFLEGAKEMLKDYTEDCIQLSSSTSTNKKLF 6138 Score = 620 bits (1598), Expect = e-174, Method: Compositional matrix adjust. Identities = 409/1248 (32%), Positives = 663/1248 (53%), Gaps = 78/1248 (6%) Query: 2085 ILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFELLHDEPVQVIHDDIPFSISYSIAEDED- 2143 IL ++G +D EE+F ++KRHE LR SF DEP+ VI D SY+ + D Sbjct: 23 ILDIKGYVDETIFEESFNEIMKRHEVLRASFNYKLDEPLHVILRDRKIKFSYNDVSNLDL 82 Query: 2144 -------EPELVKRFILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGISANILCN 2196 E +V + F L + L R+ ++ +D+ + VI HHI+ DG I+ + Sbjct: 83 NTKDLYVEKYIVDDKVKGFDLTKETLMRICLIKTNDNSYKVIWSFHHILLDGWCIGIILD 142 Query: 2197 DLISLYSGENLPGLEVQYKD---YTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTLPLD 2253 +L ++YS + G E Q +D Y+ N L+N+ + +YW + L + TLP Sbjct: 143 ELFTIYS-HKMKGEEHQLEDPRPYSDYIN-WLNNQDNEEGLKYWSKYLEGYELTATLP-K 199 Query: 2254 FPRPPVQSFDGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQEDIVI 2313 F + + +LT + L+N+ TL T++ + + ++L+KY+N ED+V Sbjct: 200 FNNSSAGKYQRREKVIEFSKELTDKITQLANKNNVTLNTVMQSIWGLILAKYNNSEDVVF 259 Query: 2314 GSPVAGRFNY--STNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQDYPFE 2371 G+ V+GR NM+G+F+NT+ R + K+F+E L K +A E DY + Sbjct: 260 GTVVSGRDAAVEGIENMLGLFINTIPTRIKLQSEKSFKEVL---KATQHDAIEGNDYNYI 316 Query: 2372 ELISKLGIERDISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYEFK------NDVAKFD 2425 L + ++ + D + V + + A+ + L++ + +G F+ + + + Sbjct: 317 NLAEVQALSN--LKSNLIDHILVFE--NYAIDEKGLEE-KESGLGFEVVSVTDEERSNYS 371 Query: 2426 LILEVIENTENLTLNFEYCAKLFQESTIIRMSERFLRILTTVVENCNVLLSDIDLLPKEE 2485 L L V E L L Y +++E I + + V+EN L DIDL+ +EE Sbjct: 372 LSLTV-GIGEKLKLTIVYDENVYEERLINNLECHIQNVTKQVIENDAKKLIDIDLISEEE 430 Query: 2486 TDRLIYTFNDTATAYPGGKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQMARM 2545 + L+Y FN+T YP + ++QLFEEQ +TP VA+ + ++TY N K+NQ+AR+ Sbjct: 431 RNILLYKFNETTVEYPKDRLIHQLFEEQVEKTPDRVAVSFKSNNLTYRELNEKSNQIARL 490 Query: 2546 LRSKGVKPDTTVGILMEHSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIM 2605 LR KGV+ +T VGI+++ S E+II + ++K+G AY+PIDP P ERI+++++DSN++++ Sbjct: 491 LREKGVQSNTIVGIMVDRSLEMIIGIMGILKSGAAYLPIDPETPKERIDYMLQDSNVKVL 550 Query: 2606 LTHKGLAEKCQFQGEFIDAASSKWYCGDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTR 2665 LT + E I+ + N +N D AYIIYTSGSTG PKGV+ Sbjct: 551 LTQDRCISQLNLNVELINLDQENFLRLSTDNLNLINHSSDTAYIIYTSGSTGTPKGVVIP 610 Query: 2666 HQGLTNYVWWGDKTYVHGEAVDFPL-YSSIAFDLSVTLIYIPLISGNKVFIYSGVSYESL 2724 H V + Y+ D L S+ AFD S+ IY L++G K+ + + SL Sbjct: 611 HYSAIRVV--KNTNYIEINENDTILQLSNYAFDGSIFDIYGALLNGAKLIMVEKDTVLSL 668 Query: 2725 --LEAVVIDNQVDFIMLTPSHLKILGEYDLSRL-KIRKFIIGGEAFDPFYAKKFFSRLAE 2781 L ++ + Q+ + +T + L + ++ L KIRK + GGE + K +L + Sbjct: 669 VKLAKLIKEEQISIMFITTALFNALVDLEIDCLDKIRKILFGGERVSVSHVNKALEKLGK 728 Query: 2782 DVEVYNVYGPTETTVACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVDQNGKLQGIGIPGE 2841 D ++ +VYGPTE+TV T YY ++ +PIG P+ N ++VVD+N L +G+PGE Sbjct: 729 D-KIIHVYGPTESTVYAT---YYFVNEVTEVIPIGKPLANTSVFVVDKNSNLLPLGVPGE 784 Query: 2842 LCIAGDGVSRGYLNREELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVK 2901 LCI+GDG+S+GYLN E LT ++FVP+PF MYRTGDLVRML DGN+EFLGR+D QVK Sbjct: 785 LCISGDGLSKGYLNNERLTVQRFVPNPFILGERMYRTGDLVRMLPDGNIEFLGRIDHQVK 844 Query: 2902 IRGHRIELGEIENQLVKQPGVNKAAVIISTGPTDSRYLCAYYTADFP---MNXXXXXXXX 2958 IRG RIELGEIE+QL+K V +A VI + +YLCAY+T++ + Sbjct: 845 IRGFRIELGEIESQLLKHKEVKEAVVIAREDNSHHQYLCAYFTSESSKGEIRVQEIRKFL 904 Query: 2959 XXXXPRHMVPSFFVQMKSIPLTASGKVDRKKLPDSFE-SFQMEDAYSAPQNFIEEKLALV 3017 P +M+P+FFVQ+ +PLT +GKVDRK LP E S Y AP+N +EEKL + Sbjct: 905 AKELPEYMIPAFFVQLDKLPLTTNGKVDRKALPSPDESSVAGVVEYEAPRNTVEEKLVSI 964 Query: 3018 WEEVLGINKVGTSNSFIKLGGDSIKAIQIVSRL-KKYGLSLEVKELFLHQNIKGISPFVK 3076 W+++L I +G ++F ++GG S+KA +VSR+ K+ + L ++++F IKGI ++ Sbjct: 965 WQDILDIENIGIQHNFFEIGGHSLKATTMVSRIHKELMVELPLRQIFQTPTIKGIGEYID 1024 Query: 3077 QNIKRHNQGTIEGPVKLTAIQKWF----FEQNFAEMHHWNQSILLHNERF--------DV 3124 + ++ +K Q ++ ++ ++ S + +N F DV Sbjct: 1025 S-----TKESVYASIKKVEEQDYYPLSSAQRRLYILNKIEGSGVSYNMPFAMKIKGDLDV 1079 Query: 3125 QFIRQAFQRITEHHDALRMVYRHTGQAGVEQSNRGLAGELFSLEVTDLTGCDDHTDLMHA 3184 + F ++ E H+ALR + V++ + + ++ E+ T+ + Sbjct: 1080 HQLENTFYKLIERHEALRTSFVMVDGEPVQKIEKEIDFQVTYREMG--------TNKLDE 1131 Query: 3185 GIKTIQKGIDLEKGPLLKLGLYQTTNGDYLAIV-IHHLVVDGVSWRIILDDFASCYLSLD 3243 I K DLEKGPLL++ + T+ +++ ++ +HH++ DGVS I+ + Y + Sbjct: 1132 MINGFVKPFDLEKGPLLRVEIIHVTDDEHVMVLDMHHIISDGVSMNILNRELCKLY---E 1188 Query: 3244 NGEEAGLIEKSDSYQKWAEALEVYANSPKLLQELAYWTDVNRIAVPAL 3291 E + L + Y W + L ++ ++ YW +V + VP L Sbjct: 1189 GKELSPLDLQYKDYAVWQKDL---FTQEEMKKQEEYWINVFKEEVPIL 1233 Score = 602 bits (1552), Expect = e-169, Method: Compositional matrix adjust. Identities = 413/1302 (31%), Positives = 676/1302 (51%), Gaps = 133/1302 (10%) Query: 2058 YPQSSSQKRLFAIEQMGGAGTAYNITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFEL 2117 YP ++ QK + AY ++ + G +D ++ +F ++++R+E LR SFE Sbjct: 2534 YPLANMQKGMLFHALENKNSKAYFEQTVMDITGYVDVEILKTSFNKIMQRYEILRASFEY 2593 Query: 2118 -LHDEPVQVIHDDIPFSISYSIAEDED--EPEL-VKRFILP-----FSLNQAPLFRVHIV 2168 + EP Q+I D + Y + E EL +K + F+L++ L RV ++ Sbjct: 2594 EIVGEPRQIIIADREIGVQYCDISERGTIEKELFIKNYREEDTEKGFNLSKDTLMRVCLI 2653 Query: 2169 SRSDHEHIVIMDMHHIIADGISANILCNDLISLYSGENLPGLEVQ------YKDYTALHN 2222 ++ + ++ HHI+ DG I+ +L ++Y G+ + G E + Y DY Sbjct: 2654 RTDENLYKLVWSHHHILLDGWCLGIVLGELFTVY-GKLINGEEYELEETKPYSDYIKW-- 2710 Query: 2223 EMLSNERIRQQGE-YWQQLLSD-----DIPSLTLPLD----FPRPPVQSFDGACYSVTLD 2272 E+ +++G+ YW+Q L IP L + + R V F Sbjct: 2711 ---LEEQDKEEGKSYWEQYLDGYEEKAQIPKLQITKNNSEYLRREKVIEFS--------- 2758 Query: 2273 SDLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRFN--YSTNNMVG 2330 ++LT + L+NR T T+ + + I+L+KY+N +++V G+ V+GR M+G Sbjct: 2759 NELTNKITQLANRNSVTFNTVFQSIWGIILAKYNNTDEVVFGTIVSGREAPVDGIEKMIG 2818 Query: 2331 MFVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQDYPFEEL-----ISKL-------- 2377 +F+N + R K++ F+E L V+ EA + +Y + L +SKL Sbjct: 2819 LFINAIPTRINLGKNQKFKEVLTVVQS---EAIASNNYNYMNLAEVQAMSKLKNDLIDHI 2875 Query: 2378 ------GIERDISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYEFKNDVAKFDLILEVI 2431 +++ I+ N D+ F V D+H ++ + Y F I Sbjct: 2876 IVFENYAVDKRIAGNEKMDIGF-------EVEDIHAEE--QSNYSFS------------I 2914 Query: 2432 ENT--ENLTLNFEYCAKLFQESTIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRL 2489 T E L L Y ++ + I + ++ V+ + N +++ID++ +EE L Sbjct: 2915 AATPGEQLNLVLTYDGNIYDDKIIDNIEMHIKKVTEQVIADENKKINEIDIIAEEERTTL 2974 Query: 2490 IYTFNDTATAYPGGKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSK 2549 +Y FNDT YP KT++QLF+EQ RTP +A+V + + +TY N K+NQ+A +LR K Sbjct: 2975 LYEFNDTKVDYPKEKTIHQLFQEQVERTPENIAVVFENKQLTYWELNEKSNQVAALLREK 3034 Query: 2550 GVKPDTTVGILMEHSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHK 2609 GVK +T VGI++E S E+I+ M A++KAGGAY+PIDP YP +R ++++DS +EI+L + Sbjct: 3035 GVKSNTVVGIMVERSIEMIVGMMAILKAGGAYLPIDPEYPEDRRRYMLEDSGIEILLKQE 3094 Query: 2610 GLAEKCQFQGEFIDAASSKWYCGDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTRHQGL 2669 ++ + ID K N S+N D+AYIIYTSGSTG PKGVM H+ + Sbjct: 3095 N--KQVDYDLTCIDINVQKIKDRFTENLPSLNKSADMAYIIYTSGSTGKPKGVMVNHKSI 3152 Query: 2670 TNYVWWGDKTYVHGEAVDFPLYSSIAFDLSVTLIYIPLISGNKVFIYSGVSYE-SLLEAV 2728 N + W ++Y + ++ S +FD SV I+ L+SG K+ + + S + Sbjct: 3153 LNTLCWRIESYQYSDSDITLQMPSFSFDSSVEDIFTTLLSGGKLILIEDIRMNFSKFINI 3212 Query: 2729 VIDNQVDFIMLTPSHLK-ILGEYDLSRLKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYN 2787 + +N+V ++ PS+ +L D L +R I GE F+ K F ++ V+++N Sbjct: 3213 IQNNKVTNLLAVPSYYNNLLNTIDKPLLDLRFVTIAGEGFNENLITKHFQKIPH-VKLFN 3271 Query: 2788 VYGPTETTVACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGD 2847 YGPTE +V T K V IG PI N ++Y++D L +G+ GELC++G+ Sbjct: 3272 EYGPTENSVCSTICEL---KQEDQKVLIGKPISNNRVYILDMENNLVPLGVAGELCVSGE 3328 Query: 2848 GVSRGYLNREELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRI 2907 G++RGYLNR ELT EKFVP+PF MYRTGDL R+L +GN+EFLGR+D QVKIRG RI Sbjct: 3329 GLARGYLNRPELTAEKFVPNPFIPGERMYRTGDLARLLPNGNIEFLGRIDHQVKIRGFRI 3388 Query: 2908 ELGEIENQLVKQPGVNKAAVIISTGPTDSRYLCAYYTADFPMNXXXXXXXX---XXXXPR 2964 ELGE+ENQL KQ + +A VI YLCAY+T++ P Sbjct: 3389 ELGEVENQLFKQKEIKEAVVIAREDNNGQPYLCAYFTSETRKKESKLQEIRKDLAQELPE 3448 Query: 2965 HMVPSFFVQMKSIPLTASGKVDRKKLPDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGI 3024 +M+P+FFVQ+ +PLTA+GKVDRK LP+ ES + Y AP+N +EE+L +W+E+LG+ Sbjct: 3449 YMIPAFFVQLDKLPLTANGKVDRKALPEPDESAVVGVEYEAPRNEVEERLVSIWQEILGV 3508 Query: 3025 NKVGTSNSFIKLGGDSIKAIQIVSRL-KKYGLSLEVKELFLHQNIKGISPFVKQNIKRHN 3083 K+G + F ++GG S+KA +VS++ K+ + + ++++F IKGI F+ Sbjct: 3509 EKIGINQHFFEIGGHSLKATTMVSKIHKELMVEIPLRQIFQTPTIKGIGEFIDS-----T 3563 Query: 3084 QGTIEGPVK---------LTAIQKWFFEQNFAEMHHWNQSI---LLHNERFDVQFIRQAF 3131 + ++ +K L++ QK + N E + + +I + DVQ + +AF Sbjct: 3564 KESVYASIKKVEEQDYYPLSSAQKRLYILNKIEGNGVSYNIPFAMKIKGDLDVQQLEKAF 3623 Query: 3132 QRITEHHDALRMVYRHTGQAGVEQSNRGLAGELFSLEVTDLTGCDDHTDLMHAGIKTIQK 3191 ++ E H+ALR + V++ + + ++ E+ G + D+++ +K Sbjct: 3624 HKLIERHEALRTSFVMVDGEPVQKIEKDIDFQVTYREM----GTNKLDDIINGFVKP--- 3676 Query: 3192 GIDLEKGPLLKLGLYQTTNGDYLAIV-IHHLVVDGVSWRIILDDFASCYLSLDNGEE-AG 3249 DLEK PLL++ + T+ +++ ++ +HH++ DGVS I + A Y NG+E + Sbjct: 3677 -FDLEKAPLLRVEIIHVTDDEHVIVLDMHHIISDGVSMGIFTQELAELY----NGKELSP 3731 Query: 3250 LIEKSDSYQKWAEALEVYANSPKLLQELAYWTDVNRIAVPAL 3291 L + Y W L ++ ++ YW V + VP L Sbjct: 3732 LSIQYKDYSVWQREL---FTQEEMKKQEEYWMHVFKEEVPVL 3770 Score = 315 bits (807), Expect = 6e-83, Method: Compositional matrix adjust. Identities = 162/443 (36%), Positives = 273/443 (61%), Gaps = 9/443 (2%) Query: 3564 MQESMLFHALKNKRSDAYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHR 3623 MQ+ +LFHA+++K SDAY EQ ILD+KG + + + ESF I+ ++++LR F YK L Sbjct: 1 MQKGILFHAIEDKNSDAYFEQIILDIKGYVDETIFEESFNEIMKRHEVLRASFNYK-LDE 59 Query: 3624 PLQIVLGSSDFHLEFEDITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDS 3683 PL ++L + D+++++ + K ++E+ D+ K FDL + LMR L+KT D+ Sbjct: 60 PLHVILRDRKIKFSYNDVSNLDLNTKDLYVEKYIVDDKVKGFDLTKETLMRICLIKTNDN 119 Query: 3684 VYQMLWSFHHILMDGWCIGIVLKDMLEHYKQLNAGSRPSLETHQ-YRLYLDWLASKNKEE 3742 Y+++WSFHHIL+DGWCIGI+L ++ Y G LE + Y Y++WL +++ EE Sbjct: 120 SYKVIWSFHHILLDGWCIGIILDELFTIYSHKMKGEEHQLEDPRPYSDYINWLNNQDNEE 179 Query: 3743 AKVYWMQYLEDYKYKELLRK--EGTSKEFRLAVLDIKLEEKVRTAVTHVASSSGITINSF 3800 YW +YLE Y+ L K ++ +++ I+ +++ +T +A+ + +T+N+ Sbjct: 180 GLKYWSKYLEGYELTATLPKFNNSSAGKYQRREKVIEFSKELTDKITQLANKNNVTLNTV 239 Query: 3801 FQAVWGILLSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRL-SGKTFHEL 3859 Q++WG++L+KY+N+EDVVFG V+SGR +EGIE M+GLFINTIP R++L S K+F E+ Sbjct: 240 MQSIWGLILAKYNNSEDVVFGTVVSGRDAAVEGIENMLGLFINTIPTRIKLQSEKSFKEV 299 Query: 3860 AGEIQSSFISSEQYGYVPLSDIQAWSH--RDLINHVMVFENYPLDREIRDTDGQQMEYGF 3917 Q I Y Y+ L+++QA S+ +LI+H++VFENY +D + + ++ GF Sbjct: 300 LKATQHDAIEGNDYNYINLAEVQALSNLKSNLIDHILVFENYAIDE--KGLEEKESGLGF 357 Query: 3918 QIAGCEILEHTNYDFSIIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTACPQ 3977 ++ E +NY S+ + GE + IVY+ Y++ I+ LE ++ + QV Sbjct: 358 EVVSVTDEERSNYSLSLTVGIGEKLKLTIVYDENVYEERLINNLECHIQNVTKQVIENDA 417 Query: 3978 IEAGDVEVLSQEEKLKLMNVFNK 4000 + D++++S+EE+ L+ FN+ Sbjct: 418 KKLIDIDLISEEERNILLYKFNE 440 Score = 169 bits (429), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 106/399 (26%), Positives = 188/399 (47%), Gaps = 16/399 (4%) Query: 1352 GVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRSTISADGNEQIVASHANADIFFAD 1411 GV ++ + ++G+L+ LE ++K++ RHE+LR++ E + D Sbjct: 1062 GVSYNMPFAMKIKGDLDVHQLENTFYKLIERHEALRTSFVMVDGEPVQKIEKEIDF---- 1117 Query: 1412 ILADYSALGDEAINQALLKENAAAFDSVMGPLIRLRVLATARHEYLLALSAHHIIADGWS 1471 Y +G +++ ++ FD GPL+R+ ++ E+++ L HHII+DG S Sbjct: 1118 -QVTYREMGTNKLDE-MINGFVKPFDLEKGPLLRVEIIHVTDDEHVMVLDMHHIISDGVS 1175 Query: 1472 LIVFLQELAALYSTECTGTRSLLPTPTPFSDYAIWQKRMLESQPKEKAAAYWKNKFSVQT 1531 + + +EL LY + L P + DYA+WQK + + +K YW N F + Sbjct: 1176 MNILNRELCKLYEG-----KELSPLDLQYKDYAVWQKDLFTQEEMKKQEEYWINVFKEEV 1230 Query: 1532 PAFELPSFRIRDAAGVRKGSRHRYVLDIPLTAKLKAVSQSMKVSLFTVLLSAYKVLLYRI 1591 P +P+ R +G+R + +D LT L +++ V+++ +LL+ Y LL R Sbjct: 1231 PILNMPTDYKRPPTQSVEGARRSFEIDSELTKNLNRIAKENGVTMYMLLLAGYTTLLSRY 1290 Query: 1592 SNHKELVVGIPTAGQMQMGQKHLVGYCLNILPFSTTINPEMTFRXXXXXXXXXXXXXXXX 1651 + ++VVG P AG+ +++VG +N L N + TFR Sbjct: 1291 TGQDDIVVGSPIAGRSHHDFENIVGMFVNTLAMRNYPNEDKTFRNYLREVKENALKAYEN 1350 Query: 1652 QDYSYASLMKELHSLDGSVHPPQINTMF---NMDKSLETPDFTGMDVELLQSPVSYSKYD 1708 QDY L+++L +TMF N+D S E + G+ E S ++ + +D Sbjct: 1351 QDYPLDELVEKLDLQRDMSRSALFDTMFVLQNLDTSNE--EIKGLSFETYDSELNIANFD 1408 Query: 1709 LSMNIVELDHELMIDFEYDPNLFDTQIITGWANYFNRIL 1747 L+++ VE ++ + D EY LF + I + +F IL Sbjct: 1409 LTLSAVETNNIIKFDLEYCTKLFKKETIAKISEHFVSIL 1447 Score = 154 bits (388), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 99/412 (24%), Positives = 192/412 (46%), Gaps = 16/412 (3%) Query: 1344 VIHSNDTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRST-ISADGNEQIVASH 1402 +++ + +GV ++ + ++G+L+ LE A+HK++ RHE+LR++ + DG Sbjct: 3591 ILNKIEGNGVSYNIPFAMKIKGDLDVQQLEKAFHKLIERHEALRTSFVMVDGEP---VQK 3647 Query: 1403 ANADIFFADILADYSALGDEAINQALLKENAAAFDSVMGPLIRLRVLATARHEYLLALSA 1462 DI D Y +G ++ ++ FD PL+R+ ++ E+++ L Sbjct: 3648 IEKDI---DFQVTYREMGTNKLDD-IINGFVKPFDLEKAPLLRVEIIHVTDDEHVIVLDM 3703 Query: 1463 HHIIADGWSLIVFLQELAALYSTECTGTRSLLPTPTPFSDYAIWQKRMLESQPKEKAAAY 1522 HHII+DG S+ +F QELA LY+ + L P + DY++WQ+ + + +K Y Sbjct: 3704 HHIISDGVSMGIFTQELAELYNG-----KELSPLSIQYKDYSVWQRELFTQEEMKKQEEY 3758 Query: 1523 WKNKFSVQTPAFELPSFRIRDAAGVRKGSRHRYVLDIPLTAKLKAVSQSMKVSLFTVLLS 1582 W + F + P +P+ R +G + +D + LK +++ V+L+ +LL+ Sbjct: 3759 WMHVFKEEVPVLNMPTDYKRPPIQSTEGDLVHFEIDSDIYVNLKKMAKEHGVTLYMLLLA 3818 Query: 1583 AYKVLLYRISNHKELVVGIPTAGQMQMGQKHLVGYCLNILPFSTTINPEMTFRXXXXXXX 1642 Y LL + + +E+VVG P AG+ K ++G +N L +++F+ Sbjct: 3819 GYTTLLSKYTGQEEIVVGSPIAGRPHDDLKQIMGIFVNTLAMRNYPKRDVSFQDYLKEVK 3878 Query: 1643 XXXXXXXXXQDYSYASLMKELHSLDGSVHPPQINTMFNMDKSLETPDF--TGMDVELLQS 1700 QDY + L+++L +TM + ++ + DF G+ Q Sbjct: 3879 DNALKAYENQDYPFDELVEKLDLKRDMSRSALFDTMLVL-QNFDYDDFEIQGLTFSPYQM 3937 Query: 1701 PVSYSKYDLSMNIVELDHELMIDFEYDPNLFDTQIITGWANYFNRILLAVLQ 1752 SK+DL++ VE + + Y LF + + A + ++ +++ Sbjct: 3938 KAHVSKFDLTLTAVEEERSIKCVLNYRTKLFKKETVERLAKHLIQVFKEIIE 3989 Score = 113 bits (283), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 101/429 (23%), Positives = 198/429 (46%), Gaps = 28/429 (6%) Query: 1340 QISLVIHS-NDTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRSTISADGNEQI 1398 Q ++ H+ D + + E + L ++G +++ E ++++++ RHE LR++ + +E + Sbjct: 2 QKGILFHAIEDKNSDAYFEQIILDIKGYVDETIFEESFNEIMKRHEVLRASFNYKLDEPL 61 Query: 1399 VASHANADIFFADILADYSALG----DEAINQALLKENAAAFDSVMGPLIRLRVLATARH 1454 + I F+ D S L D + + ++ + FD L+R+ ++ T + Sbjct: 62 HVILRDRKIKFS--YNDVSNLDLNTKDLYVEKYIVDDKVKGFDLTKETLMRICLIKTNDN 119 Query: 1455 EYLLALSAHHIIADGWSLIVFLQELAALYSTECTGTRSLLPTPTPFSDYAIWQKRMLESQ 1514 Y + S HHI+ DGW + + L EL +YS + G L P P+SDY W L +Q Sbjct: 120 SYKVIWSFHHILLDGWCIGIILDELFTIYSHKMKGEEHQLEDPRPYSDYINW----LNNQ 175 Query: 1515 PKEKAAAYWKNKFSVQTPAFELPSFRIRDAAGVRKGSRHRYVLDIP--LTAKLKAVSQSM 1572 E+ YW LP F +AG K R V++ LT K+ ++ Sbjct: 176 DNEEGLKYWSKYLEGYELTATLPKFN-NSSAG--KYQRREKVIEFSKELTDKITQLANKN 232 Query: 1573 KVSLFTVLLSAYKVLLYRISNHKELVVGIPTAGQMQM--GQKHLVGYCLNILPFSTTINP 1630 V+L TV+ S + ++L + +N +++V G +G+ G ++++G +N +P + Sbjct: 233 NVTLNTVMQSIWGLILAKYNNSEDVVFGTVVSGRDAAVEGIENMLGLFINTIPTRIKLQS 292 Query: 1631 EMTFRXXXXXXXXXXXXXXXXQDYSYASL--MKELHSLDGSV--HPPQINTMFNMDKSLE 1686 E +F+ DY+Y +L ++ L +L ++ H +K LE Sbjct: 293 EKSFK---EVLKATQHDAIEGNDYNYINLAEVQALSNLKSNLIDHILVFENYAIDEKGLE 349 Query: 1687 TPDFTGMDVELLQ-SPVSYSKYDLSMNIVELDHELMIDFEYDPNLFDTQIITGWANYFNR 1745 + +G+ E++ + S Y LS+ V + +L + YD N+++ ++I + Sbjct: 350 EKE-SGLGFEVVSVTDEERSNYSLSLT-VGIGEKLKLTIVYDENVYEERLINNLECHIQN 407 Query: 1746 ILLAVLQPD 1754 + V++ D Sbjct: 408 VTKQVIEND 416 Score = 113 bits (283), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 104/445 (23%), Positives = 205/445 (46%), Gaps = 54/445 (12%) Query: 3580 AYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPLQIVLGSSDFHLEFE 3639 +Y+ + +KGD+ L +F ++ +++ LRT FV P+Q + DF + + Sbjct: 1064 SYNMPFAMKIKGDLDVHQLENTFYKLIERHEALRTSFVMVD-GEPVQKIEKEIDFQVTYR 1122 Query: 3640 DITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVYQMLWSFHHILMDGW 3699 ++ + E + K FDL +GPL+R ++ D + M+ HHI+ DG Sbjct: 1123 EMGTNKLDEMINGFV--------KPFDLEKGPLLRVEIIHVTDDEHVMVLDMHHIISDGV 1174 Query: 3700 CIGIVLKDMLEHYKQLNAGSRPSLETHQYRLYLDW----LASKNKEEAKVYWMQYLE--- 3752 + I+ +++ + Y+ G S QY+ Y W + ++ + YW+ + Sbjct: 1175 SMNILNRELCKLYE----GKELSPLDLQYKDYAVWQKDLFTQEEMKKQEEYWINVFKEEV 1230 Query: 3753 -------DYKYKELLRKEGTSKEFRLAVLDIKLEEKVRTAVTHVASSSGITINSFFQAVW 3805 DYK EG + F +++ ++ + +A +G+T+ A + Sbjct: 1231 PILNMPTDYKRPPTQSVEGARRSF-------EIDSELTKNLNRIAKENGVTMYMLLLAGY 1283 Query: 3806 GILLSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRLS-GKTFHELAGEIQ 3864 LLS+Y +D+V G+ I+GRS E +VG+F+NT+ +R + KTF E++ Sbjct: 1284 TTLLSRYTGQDDIVVGSPIAGRSHH--DFENIVGMFVNTLAMRNYPNEDKTFRNYLREVK 1341 Query: 3865 SSFISSEQYGYVPLSDI-------QAWSHRDLINHVMVFENYPLDREIRDTDGQQME-YG 3916 + + + + PL ++ + S L + + V +N DT ++++ Sbjct: 1342 ENALKAYENQDYPLDELVEKLDLQRDMSRSALFDTMFVLQNL-------DTSNEEIKGLS 1394 Query: 3917 FQIAGCEILEHTNYDFSI-IIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTAC 3975 F+ E L N+D ++ +E + Y + KETI+ + + ++I+ ++T Sbjct: 1395 FETYDSE-LNIANFDLTLSAVETNNIIKFDLEYCTKLFKKETIAKISEHFVSILREITNN 1453 Query: 3976 PQIEAGDVEVLSQEEKLKLMNVFNK 4000 ++ G +++LS EEK L+N FN+ Sbjct: 1454 QEVCLGQIDMLSGEEKHILLNEFNE 1478 Score = 113 bits (282), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 104/430 (24%), Positives = 189/430 (43%), Gaps = 29/430 (6%) Query: 1340 QISLVIHS-NDTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRSTISADGNEQ- 1397 Q ++ H+ D + E + + ++G ++ E + + ++ RHE LR+ I + EQ Sbjct: 5090 QQGMLFHALEDPQSGAYFEQLVIDVKGFIDVNLFEESLNDIMKRHEILRTAIEYEITEQP 5149 Query: 1398 --IVASHANADIFFADILADYSALGDEAINQALLKENAAAFDSVMGPLIRLRVLATARHE 1455 ++ + DI E+I + ++ FD LIRL ++ T Sbjct: 5150 KNVIIKGRKIGFRYRDIRQQGIDQQKESITTYIEQDREKGFDFSKDVLIRLELIQTDDKA 5209 Query: 1456 YLLALSAHHIIADGWSLIVFLQELAALYSTECTGTRSLLPTPTPFSDYAIWQKRMLESQP 1515 Y + S HHI+ DGW + L EL +Y + G L P P+SDY W L Q Sbjct: 5210 YTIIWSNHHILFDGWGRGIILGELFHIYGNKQVGQYPNLEEPRPYSDYIRW----LGEQE 5265 Query: 1516 KEKAAAYWKNKFS-VQTPAFELPSFRIRDAAGVRKGSRHRYVLDIPLTAKLKAVSQSMKV 1574 KE+ YWK + Q PA ++PSF+I D+ G LT K+ ++ V Sbjct: 5266 KEEGIQYWKQYLAGYQKPA-KVPSFKI-DSTREYHGQETLIEFSRELTKKMTELANQNNV 5323 Query: 1575 SLFTVLLSAYKVLLYRISNHKELVVGIPTAGQ--MQMGQKHLVGYCLNILPFSTTINPEM 1632 +L TVL + + ++L + ++ ++V G +G+ G + +VG +N +P I + Sbjct: 5324 TLNTVLQTLWGIILAKYNHTDDVVFGSVVSGRDAKVAGIEKMVGLFINAIPTRINIKEQK 5383 Query: 1633 TFRXXXXXXXXXXXXXXXXQDYSYASL--MKELHSLDGS-VHPPQINTMFNMDKSL---- 1685 +F+ Q Y+Y +L ++ L L + I + +D+ L Sbjct: 5384 SFK---NILKEVQQQAIESQAYNYMNLSDIQSLSDLKRDLIDHVMIFENYALDERLLQEE 5440 Query: 1686 -ETPDFTGMDVELLQSPVSYSKYDLSMNIVELDHELMIDFEYDPNLFDTQIITGWANYFN 1744 F D++ ++ + Y ++ +V +L++ YD NL+ ++I AN+ Sbjct: 5441 ESKSSFVFKDIKGIEQ----TNYGFTIVVVP-GEQLVLKISYDGNLYSEKLIQNIANHLK 5495 Query: 1745 RILLAVLQPD 1754 I+ V+Q + Sbjct: 5496 NIMDEVVQDE 5505 Score = 107 bits (266), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 88/312 (28%), Positives = 137/312 (43%), Gaps = 29/312 (9%) Query: 1790 GVSWDEADIFVILDKDMHPSPVGVPGEVYLA-------RLTEPSLLAEQ-------PSTS 1835 G D I+ ILD + PVG+ GE+Y++ L P L AE+ P Sbjct: 5847 GKPIDNVQIY-ILDDNQKILPVGIEGELYISGDGVATGYLNRPELTAEKFISNPYVPGAK 5905 Query: 1836 ---TGIMAMYTADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGT 1892 TG +A + I+ IG + G I L I+ Q++ I V + G Sbjct: 5906 MYRTGDLARWLPSGNIEFIGRTDHQVKIRGYRIELGEIENQILKLDNIKETKVVARIDG- 5964 Query: 1893 FQRDQKILAYITPRGTSIP-KVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERL 1951 + Q + AY+ V E++++L +P IP+ F L E+PL + G I+ Sbjct: 5965 -EDSQYLCAYVVLENKEKAITVTEMRRYLSKELPNYMIPAFFTQLKELPLTTNGKIDINS 6023 Query: 1952 LPAFDEDKALREEIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFS 2011 LPA D + E P N+ EE++ IW +LN++ + N + F++G NSL Sbjct: 6024 LPAPDGNVQYGLEYEPPRNDLEEKIVSIWEEILNIKKIGMNTNLFDIGANSLNVMTFVSR 6083 Query: 2012 IQKEFSTDISLRMLFEHPTVKGLAKAINGAGKSFLPEITPLGKKDWYPQSSS---QKRLF 2068 I E + + + +F+ PTV+ + + GA K L + T +D SSS K+LF Sbjct: 6084 IVAELNFRVPFKDVFDKPTVRSFSAFLEGA-KEMLKDYT----EDCIQLSSSTSTNKKLF 6138 Query: 2069 AIEQMGGAGTAY 2080 G AY Sbjct: 6139 CFPPAASIGIAY 6150 Score = 92.4 bits (228), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 70/304 (23%), Positives = 136/304 (44%), Gaps = 14/304 (4%) Query: 1340 QISLVIHS-NDTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRSTISAD---GN 1395 Q ++ H+ + + + E + + G ++ L+T+++K++ R+E LR++ + Sbjct: 2540 QKGMLFHALENKNSKAYFEQTVMDITGYVDVEILKTSFNKIMQRYEILRASFEYEIVGEP 2599 Query: 1396 EQIVASHANADIFFADILADYSALGDEAINQALLKENAAAFDSVMGPLIRLRVLATARHE 1455 QI+ + + + DI + + I ++ F+ L+R+ ++ T + Sbjct: 2600 RQIIIADREIGVQYCDISERGTIEKELFIKNYREEDTEKGFNLSKDTLMRVCLIRTDENL 2659 Query: 1456 YLLALSAHHIIADGWSLIVFLQELAALYSTECTGTRSLLPTPTPFSDYAIWQKRMLESQP 1515 Y L S HHI+ DGW L + L EL +Y G L P+SDY W LE Q Sbjct: 2660 YKLVWSHHHILLDGWCLGIVLGELFTVYGKLINGEEYELEETKPYSDYIKW----LEEQD 2715 Query: 1516 KEKAAAYWKNKFSVQTPAFELPSFRIRDAAGVRKGSRHRYVLDIP--LTAKLKAVSQSMK 1573 KE+ +YW+ ++P +I + R V++ LT K+ ++ Sbjct: 2716 KEEGKSYWEQYLDGYEEKAQIPKLQI--TKNNSEYLRREKVIEFSNELTNKITQLANRNS 2773 Query: 1574 VSLFTVLLSAYKVLLYRISNHKELVVGIPTAGQMQM--GQKHLVGYCLNILPFSTTINPE 1631 V+ TV S + ++L + +N E+V G +G+ G + ++G +N +P + Sbjct: 2774 VTFNTVFQSIWGIILAKYNNTDEVVFGTIVSGREAPVDGIEKMIGLFINAIPTRINLGKN 2833 Query: 1632 MTFR 1635 F+ Sbjct: 2834 QKFK 2837 >B1A907.1 B1A907_PAEPO Fusaricidin synthetase (Fragment) Length = 5842 Score = 1578 bits (4086), Expect = 0.0, Method: Compositional matrix adjust. Identities = 866/2244 (38%), Positives = 1304/2244 (58%), Gaps = 74/2244 (3%) Query: 1801 ILDKDMHPSPVGVPGEVYLARL-------TEPSLLAEQ-------PSTS---TGIMAMYT 1843 ILD+ PVGV GE+ ++ + P L+ E+ P TG + + Sbjct: 1262 ILDEHFRLLPVGVAGELCISGIGLARGYHNRPELMDEKFVDNPYAPGERMYRTGDLVRWL 1321 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKILAYI 1903 ++ I+ +G + G I L ++ ++ P + V S +D ++AY Sbjct: 1322 SNGTIEYLGRIDHQVKIRGYRIELGEVEAHMLRVPSVQEVVVLAVESDDGYKD--LVAYF 1379 Query: 1904 TPRGTSIPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKALRE 1963 +V E++ L +PG IPS F+ L+++PL S G I+ + L DE Sbjct: 1380 V--AAQKLEVSELRADLSEMLPGYMIPSRFIQLEDMPLTSNGKIDRKALQ--DERGWAAT 1435 Query: 1964 EIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDISLR 2023 P+ E +LAEIW+ VL +E D+FF GG+SL+A+LL I+KE + +ISLR Sbjct: 1436 SSEAPKTPIEIQLAEIWQEVLGVESAGVKDNFFHFGGHSLRAALLVSRIRKEMNREISLR 1495 Query: 2024 MLFEHPTVKGLAKAINGAGKSFLPEITPLGKKDWYPQSSSQKRLFAIEQMGGAGTAYNIT 2083 +F PT++GLA+AI G EI + YP SS+QKRLF + Q+ G +YN+ Sbjct: 1496 EVFGSPTIEGLARAIEGYTPLNFEEIPTAEARKHYPLSSAQKRLFILSQLEGGELSYNMP 1555 Query: 2084 GILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFELLHDEPVQVIHDDIPFSISYS-IAEDE 2142 GIL VEG L+ R+E+AF+RL++RH LRT F ++ EPVQ I D+PF++ Y+ ++E E Sbjct: 1556 GILTVEGDLNRERLEQAFRRLIRRHGSLRTRFVTVNGEPVQQILPDVPFTVEYAELSESE 1615 Query: 2143 DEPELVKRFILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGISANILCNDLISLY 2202 E L ++F+ PF L +APL RV ++ + H+++ DMHHI++DG+S NIL + + Y Sbjct: 1616 AEATL-QQFVRPFDLGEAPLLRVGLIRIAHERHLLLFDMHHIVSDGVSMNILIEEFLRFY 1674 Query: 2203 SGEN-LPGLEVQYKDYTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQS 2261 E+ LP L++QY DY E L ER++ Q YW +P L P+D RP V+S Sbjct: 1675 QEEDVLPALQIQYADYAVWQQEQLGRERLKAQEAYWLDAFRGSLPVLDSPVDEVRPAVRS 1734 Query: 2262 FDGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRF 2321 F G +D+ L+ L+ L+ R +TL+ +LLA+Y LL KY+ QED+++GSPV GR Sbjct: 1735 FAGDRIDFQIDASLSASLQELATRTGSTLFMVLLAAYTTLLHKYTGQEDVIVGSPVPGRS 1794 Query: 2322 NYSTNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIER 2381 + + ++GMFV T+AMR P K+F+ +L EVKE L A+ENQDYP EEL+ KL ++R Sbjct: 1795 HATLEGLIGMFVGTVAMRTYPEGEKSFEAYLQEVKETALRAYENQDYPLEELVEKLQLQR 1854 Query: 2382 DISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYEFKNDVAKFDLILEVIENTENLTLNF 2441 D+SRNP+FD FVLQ+ + + ++ +R Y+ + AKFDL L V E L Sbjct: 1855 DLSRNPLFDTTFVLQNTEQG--EQEIEGLRFTPYDHVHPAAKFDLTLTVSEADGTLNCTL 1912 Query: 2442 EYCAKLFQESTIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYP 2501 EY +++ T RM+ F++++ + N + LS +D++ +E L+ ++ YP Sbjct: 1913 EYATAIYKRETAERMAGHFVQLIQEAIANPGMSLSSLDIVTPQEKSMLMKDADEAKADYP 1972 Query: 2502 GGKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILM 2561 KT++ LFEEQA R P AVA+V + +++Y N + N +AR LR +G++PD VGI+ Sbjct: 1973 RDKTIHALFEEQAVRNPDAVAVVCEEATLSYSELNERANGLARTLRERGLQPDGLVGIMA 2032 Query: 2562 EHSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEF 2621 + S E+++ + A++KAGGAYVP+DP YP +RI F+++DS +++LT L + F G+ Sbjct: 2033 DRSLEMVVGILAILKAGGAYVPVDPEYPEDRIRFMLEDSGAKLLLTQAHLETRVSFTGDV 2092 Query: 2622 IDAASSKWYCGDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYV 2681 I+ Y D SN P+ LAY+IYTSG+TG PKG + H+ + ++ + Sbjct: 2093 INLDEPASYKEDISNLEPAAGPNHLAYVIYTSGTTGKPKGTLIEHKNVVRLLFNDKNMFD 2152 Query: 2682 HGEAVDFPLYSSIAFDLSVTLIYIPLISGNKVFIYSGVSY---ESLLEAVVIDNQVDFIM 2738 G + L+ S FD SV +Y L++G ++ I ++ E L+ ++ D +V + Sbjct: 2153 FGSQDTWTLFHSFCFDFSVWEMYGALLNGGRLVIVPSLTAKGPERFLQ-LLKDQKVTVLN 2211 Query: 2739 LTPSHLKILGEYDLS----RLKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTET 2794 TP++ L + +LS L +R I GGEA P K + ++ + V++ N+YG TET Sbjct: 2212 QTPTYFYQLLQEELSHRAAELSLRMIIFGGEALSPALLKDWRAKYPQ-VQLINMYGITET 2270 Query: 2795 TVACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYL 2854 T T+ + + IG PI ++ Y++D+ + Q IGIPGEL +AG+G++RGYL Sbjct: 2271 TAHVTYKEITELEIEQGRSNIGIPIPTLRAYILDEQRRPQPIGIPGELYVAGEGLARGYL 2330 Query: 2855 NREELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIEN 2914 NR ELT EKFV PF+ MYR+GDL R L DG++E+LGR+D QVKIRG+RIELGE+E Sbjct: 2331 NRPELTEEKFVAHPFEAGERMYRSGDLARWLPDGSMEYLGRIDHQVKIRGYRIELGEVEA 2390 Query: 2915 QLVKQPGVNKAAVIISTGPTDSRYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFFVQM 2974 +L+ P V +A V+ + + L Y+TAD + P +M+PS+F+Q+ Sbjct: 2391 KLLHAPSVREAVVLAREDGSGQKVLVGYFTADQMLTVGELRKALAAELPAYMIPSYFMQL 2450 Query: 2975 KSIPLTASGKVDRKKLPDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSFI 3034 + +PLT +GK+DRK LP + Q Y AP+N EE LA VW+ VLG ++G + F Sbjct: 2451 EQMPLTPNGKLDRKALPAPEANVQTGAVYEAPRNAAEEALASVWQGVLGAQQIGIHDHFF 2510 Query: 3035 KLGGDSIKAIQIVSRLKKYGLSLEVKELFLHQNIKGISPFVKQNIKRHNQGTIEGPVKLT 3094 LGGDSIKAIQ+ S+L + G LE+K+LF + I +SP+++ + QG I+G +L Sbjct: 2511 DLGGDSIKAIQVSSKLFQSGYKLEMKDLFKYPTIAELSPYLQVAGRTAEQGEIKGAAELM 2570 Query: 3095 AIQKWFFEQNFAEMHHWNQSILLH-NERFDVQFIRQAFQRITEHHDALRMVYRHTGQAGV 3153 IQ+WFFE++ AE HH+N +++LH + FD +R +I HHD LRMV+R T +AG Sbjct: 2571 PIQRWFFERHTAEPHHYNHAVMLHRKDGFDEAALRLTMDQIAIHHDVLRMVFRPT-EAGY 2629 Query: 3154 EQSNRGL-AGELFSLEVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGD 3212 NRG+ GEL++L++ D+ DD + A IQ LE GPL KLGL +GD Sbjct: 2630 TAWNRGVDEGELYTLDIADMRQADDEVAAVQAQADAIQASFHLEDGPLFKLGLSHCKDGD 2689 Query: 3213 YLAIVIHHLVVDGVSWRIILDDFASCYLSLDNGEEAGLIEKSDSYQKWAEALEVYANSPK 3272 +L IVIHHL+VDGVSWRI+ +D A+ Y NG+ L +K+DSY W+E YA P Sbjct: 2690 HLLIVIHHLLVDGVSWRILFEDIATGYEQALNGQAIVLPQKTDSYLVWSEQAAKYAAGPA 2749 Query: 3273 LLQELAYWTDVNRIAVPALPKDSEAGNGKIKDRYQTKTVLSEKETTNLLRHAGDAYQTET 3332 L +E +YW + + LPKD + G I+D S +ET LLR A AY TET Sbjct: 2750 LDKERSYWQQIEETVLTPLPKDQDQEPGTIRDTESVTVTWSTEETDLLLRQANRAYHTET 2809 Query: 3333 XXXXXXXXXXXIKGWANVDRVRINMEGHGREALIQDLDITRTVGWFTSTYPLVLELANSH 3392 I+ W +++V +N+EGHGRE +I DLDITRTVGWFT+ YP++L L + Sbjct: 2810 NDLLLTALGAAIQRWTGMEQVLVNLEGHGREMIIPDLDITRTVGWFTTQYPVLLNLQDGQ 2869 Query: 3393 ELPLHIMTTKETIRQTPNKGMGYQVLKYLTSPELRAAVDFNVMPEISFNYLGQF-----G 3447 E+ + I KE +R+ P+KG+GY +LKY+ +PE F+V PE+SFNYLGQF G Sbjct: 2870 EVSIRIKRIKENLREVPHKGIGYGLLKYM-APE--KDTRFSVEPEVSFNYLGQFDQDLEG 2926 Query: 3448 NEASYGTFEICNTFMESTESPESHRPYAIDINAMIVGNRVEIRVDYNPGQFNEATMSRFA 3507 N S T + + T P+ YA+D+N M+ ++ + + Y+ Q+ + T+S FA Sbjct: 2927 NALSLSTHSVGKALSDYT--PQQ---YALDVNGMVAEGQLSLTITYSNRQYRKETVSHFA 2981 Query: 3508 ELLLNSLKLIISHCTREERIQRSPSDLTYKKLTFEELDDL--NRLYPGGITDVYTMTPMQ 3565 ELL +SL +I HC +ER+Q +PSD+ ++ LT E+LD L + G I DVY +T MQ Sbjct: 2982 ELLQSSLSEVIRHCVAQERVQLTPSDVLFQGLTLEQLDRLTAQTAHIGEIEDVYKLTAMQ 3041 Query: 3566 ESMLFHALKNKRSDAYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPL 3625 + MLFH+L S +Y EQ +L+G + ESF+ + ++ ILRT F PL Sbjct: 3042 KGMLFHSLLEPDSSSYFEQASFELRGSFDVDTFFESFQALAQRHAILRTGFYNNITDVPL 3101 Query: 3626 QIVLGSSDFHLEFEDITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVY 3685 Q+V L + D+ E+ A ++ D K F L + PL R +L+ S + Sbjct: 3102 QVVFKQRPIPLNYVDLRAATLEEQEAQIQAYTTEDMAKGFSLSEDPLTRVTVLQKEQS-H 3160 Query: 3686 QMLWSFHHILMDGWCIGIVLKDMLEHYKQLNAGSRPSLETHQ-YRLYLDWLASKNKEEAK 3744 +LWSFHHI+MDGWCI I+ +++ ++Y +P L Q Y Y++WL +++ +EA Sbjct: 3161 LVLWSFHHIVMDGWCIPIITQELFDYYSAPRQQVQPVLPPAQPYSRYIEWLDAQDDQEAS 3220 Query: 3745 VYWMQYLEDY---------KYKELLRKEGTSKEFRLAVLDIKLEEKVRTAVTHVASSSGI 3795 YW QYLEDY K K ++EG + L L K+ VA + + Sbjct: 3221 TYWSQYLEDYDGNTVLPEAKTKSQAKEEGYVLNEHVLHLGTALTRKMDV----VAKRNHV 3276 Query: 3796 TINSFFQAVWGILLSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRLS-GK 3854 T+N+ Q WG++L +Y+ + DVVFG V+SGR EI GIE MVGLFINT+P+RV+ S + Sbjct: 3277 TVNTLMQTAWGLILQRYNASSDVVFGGVVSGRPAEIAGIENMVGLFINTVPIRVQSSKDE 3336 Query: 3855 TFHELAGEIQSSFISSEQYGYVPLSDIQAWS--HRDLINHVMVFENYPLDREIRDTDGQQ 3912 F E+ Q+ ++ Y PL +IQ + +DLI+H+M+FENYPLD ++ + G Sbjct: 3337 AFVEVMKRTQAHSLAGRAYDTYPLYEIQGKTTQKQDLISHIMIFENYPLDEQVEQS-GNH 3395 Query: 3913 MEYGFQIAGCEILEHTNYDFSIIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQV 3972 E ++A + E TNYDF++++ PGED + I YNA Y++E+I+ + +LL ++ QV Sbjct: 3396 TEDNLEVANFAMFEQTNYDFNLVVIPGEDIKVCIRYNASVYEQESIARIGGHLLQMLDQV 3455 Query: 3973 TACPQIEAGDVEVLSQEEKLKLMN 3996 PQ ++E+++ EE+ L++ Sbjct: 3456 ATRPQATIQELEIVTTEERTNLLD 3479 Score = 1284 bits (3322), Expect = 0.0, Method: Compositional matrix adjust. Identities = 716/1985 (36%), Positives = 1113/1985 (56%), Gaps = 62/1985 (3%) Query: 2055 KDWYPQSSSQKRLFAIEQMGGAGTAYNITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTS 2114 +D Y ++ QK + + ++Y + G D E+FQ L +RH LRT Sbjct: 3032 EDVYKLTAMQKGMLFHSLLEPDSSSYFEQASFELRGSFDVDTFFESFQALAQRHAILRTG 3091 Query: 2115 F-ELLHDEPVQVIHDDIPFSISY---SIAEDEDEPELVKRFILP-----FSLNQAPLFRV 2165 F + D P+QV+ P ++Y A E++ ++ + FSL++ PL RV Sbjct: 3092 FYNNITDVPLQVVFKQRPIPLNYVDLRAATLEEQEAQIQAYTTEDMAKGFSLSEDPLTRV 3151 Query: 2166 HIVSRSDHEHIVIMDMHHIIADGISANILCNDLISLYSGENLPGLEVQ--------YKDY 2217 ++ + + H+V+ HHI+ DG I+ +L YS P +VQ Y Y Sbjct: 3152 TVLQK-EQSHLVLWSFHHIVMDGWCIPIITQELFDYYSA---PRQQVQPVLPPAQPYSRY 3207 Query: 2218 TALHNEMLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQSFDGAC---YSVTLDSD 2274 E L + ++ YW Q L D + LP + + +G + + L + Sbjct: 3208 I----EWLDAQDDQEASTYWSQYLEDYDGNTVLPEAKTKSQAKE-EGYVLNEHVLHLGTA 3262 Query: 2275 LTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRFN--YSTNNMVGMF 2332 LTR + V++ R T+ TL+ ++ ++L +Y+ D+V G V+GR NMVG+F Sbjct: 3263 LTRKMDVVAKRNHVTVNTLMQTAWGLILQRYNASSDVVFGGVVSGRPAEIAGIENMVGLF 3322 Query: 2333 VNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIERD-ISRNPVFDV 2391 +NT+ +R Q +K + F E + + ++L YP E+ K ++D IS +F+ Sbjct: 3323 INTVPIRVQSSKDEAFVEVMKRTQAHSLAGRAYDTYPLYEIQGKTTQKQDLISHIMIFEN 3382 Query: 2392 MFVLQSLDLAVPDVHLDDIRLNGYEFKNDVAKFDLILEVIENTENLTLNFEYCAKLFQES 2451 + + ++ + D++ + + +D L VI E++ + Y A ++++ Sbjct: 3383 YPLDEQVEQSGNHTE-DNLEVANFAMFEQT-NYDFNLVVIPG-EDIKVCIRYNASVYEQE 3439 Query: 2452 TIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYPGGKTVYQLFE 2511 +I R+ L++L V + +++++ EE L+ + A YP + ++ LFE Sbjct: 3440 SIARIGGHLLQMLDQVATRPQATIQELEIVTTEERTNLL-DWGGKAHVYPSDQGLHTLFE 3498 Query: 2512 EQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILMEHSFELIISM 2571 EQ ARTP +A + ITY N N++A L ++G++ + VG+L + S EL++++ Sbjct: 3499 EQVARTPDKIAAISGDIQITYRELNEWANRLASTLIAQGLRSEQVVGLLADRSVELLVAI 3558 Query: 2572 FAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEFIDAASSKWYC 2631 V+KAGGAYVPIDP YP ERI +I+KDS EI+LT L + F+G ++ S Y Sbjct: 3559 MGVLKAGGAYVPIDPEYPQERIQYILKDSGAEILLTQSHLTKLASFEGMVMELDSPHIYG 3618 Query: 2632 GDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYVHGEAVDFPLY 2691 +NP +DL Y+IYTSG+TG PKG M H+G+ NY+WW +K Y G+ DFPLY Sbjct: 3619 TGVNNPNIPVRGNDLVYLIYTSGTTGNPKGTMINHKGIVNYIWWANKVYCAGQPTDFPLY 3678 Query: 2692 SSIAFDLSVTLIYIPLISGNKVFIYSGVSYESLLEAVVIDNQVDFIMLTPSHLKILGEYD 2751 SSI+FDL++T ++ PLI+G V IY G+ +++ ++ +N VD + LTP+HL ++ + Sbjct: 3679 SSISFDLTMTSMFTPLINGGIVRIYDGIDKAEVVQHILRENAVDILKLTPTHLSLIKDMT 3738 Query: 2752 L-SRLKIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDLR 2810 + + +I++ I+GGE +K ++++YN YGPTET V C + Y P KD R Sbjct: 3739 IPAESRIQQLIVGGENLTTHLSKTITDLFGGNIKIYNEYGPTETVVGCMIHLYDPAKDTR 3798 Query: 2811 NPVPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPFQ 2870 VPIG P N+ ++++D+ +L +G+ GE+ IAGDGV+RGYLNR +LT EKF+ +PF Sbjct: 3799 ESVPIGLPSDNIYIHILDEQLRLVPLGVEGEMYIAGDGVARGYLNRPDLTAEKFIRNPFA 3858 Query: 2871 TSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVIIS 2930 G MYRTGDL R L +G++E++GR+D QVKIRG+RIELGEIE +L+ P V +A V+ Sbjct: 3859 AEGNMYRTGDLARRLPNGDIEYIGRIDHQVKIRGYRIELGEIEAKLLDMPLVEEALVVAW 3918 Query: 2931 TGPTDSRYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFFVQMKSIPLTASGKVDRKKL 2990 + LCAY+ AD M+ P +M+PS+FVQM +PLT +GK+DRK L Sbjct: 3919 ADANGQKSLCAYFVADREMSVSELRNELSAELPAYMIPSYFVQMDVMPLTPNGKLDRKAL 3978 Query: 2991 PDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIVSRL 3050 P+ + A++AP+ +E LA +W+ VLG+ VG ++F +LGGDSIK+IQ+ SRL Sbjct: 3979 PEPNVGVKAGAAFAAPRTDVENILASIWQGVLGVPLVGIHDNFFELGGDSIKSIQVSSRL 4038 Query: 3051 KKYGLSLEVKELFLHQNIKGISPFVKQNIKRHNQGTIEGPVKLTAIQKWFFEQNFAEMHH 3110 G LE+K+LF + I ++ V + +Q + G VKL ++ F E+ ++HH Sbjct: 4039 LHAGYKLEMKDLFSYPTIAELAQRVSAVSRIADQSEVHGTVKLGPARRRFLEEQSTDLHH 4098 Query: 3111 WNQSILLH-NERFDVQFIRQAFQRITEHHDALRMVYRHTGQAGVEQSNRGLA-GELFSLE 3168 +NQS++L+ E F+ + + Q+I EHHDALR+V+R G+ GVE NR L GEL+SL+ Sbjct: 4099 FNQSVMLYRREGFNTDALAKVIQKIAEHHDALRLVFRQ-GEHGVEAWNRSLGEGELYSLQ 4157 Query: 3169 VTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDYLAIVIHHLVVDGVSW 3228 + DL D + AG + IQ+ I LE GPL +LGL++ T G++L I+IHHL VDGVSW Sbjct: 4158 IHDLRDEKDPALAIEAGAEAIQRSISLEDGPLFRLGLFRCTEGEHLLIIIHHLAVDGVSW 4217 Query: 3229 RIILDDFASCYLSLDNGEEAGLIEKSDSYQKWAEALEVYANSPKLLQELAYWTDVNRIAV 3288 RI+ +D Y GE L +K+DSY+ W + + YANSP QE ++W +V Sbjct: 4218 RILFEDLQEGYEQAARGEAVKLPQKTDSYRAWVDGITQYANSPAAEQERSFWAEVEGEGF 4277 Query: 3289 PALPKDSEAGNGKIKDRYQTKTVLSEKETTNLLRHAGDAYQTETXXXXXXXXXXXIKGWA 3348 LPKD G IKD S +ET L+ A Y TE ++ W Sbjct: 4278 ALLPKDKVDGALLIKDSEAVTVTWSAEETEQFLKEANRTYNTEVNDLLLTALGMAVQEWT 4337 Query: 3349 NVDRVRINMEGHGREALIQDLDITRTVGWFTSTYPLVLELANSHELPLHIMTTKETIRQT 3408 ++RV I +EGHGRE ++ +LDITRT+GWFTS YP+ LE+ E+ I KE +R+ Sbjct: 4338 GIERVGILLEGHGREPVVPELDITRTIGWFTSQYPVALEMGGEMEIGARIKRIKEDLRRI 4397 Query: 3409 PNKGMGYQVLKYLTSPELRAAVDFNVMPEISFNYLGQFGNEASYGTFEICNTFMESTESP 3468 PNKG+GY +LKYL+ ++ F+ PEI+FNYLGQF + + GT E+ S S Sbjct: 4398 PNKGVGYGILKYLS--DVSDGSSFSAEPEITFNYLGQFDQDLAEGTMEVSPYSAGSEVSE 4455 Query: 3469 ESHRPYAIDINAMIVGNRVEIRVDYNPGQFNEATMSRFAELLLNSLKLIISHCTREERIQ 3528 + + A++IN MI ++++ V YN QF+ ++ F +L L +I HC R+ER + Sbjct: 4456 QMVQHQALNINGMITEGQLQLSVSYNHQQFHADSVENFVGILEERLSEVIGHCVRKERTE 4515 Query: 3529 RSPSDLTYKKLT--FEELDDLNRLYPGGITDVYTMTPMQESMLFHALKNKRSDAYHEQCI 3586 +PSD+ K ++ E + + G I ++Y +TPMQ+ MLFH+L S+ Y EQ Sbjct: 4516 LTPSDVLLKDISLEEIEELEEQTRHIGSIENMYKLTPMQKGMLFHSLLEPHSEVYFEQAT 4575 Query: 3587 LDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPLQIVLGSSDFHLEFEDITHMES 3646 +++G E S + ++ ++ ILRT F P+QIV +ED+ +ES Sbjct: 4576 FEIQGVFYPEDFKRSLQHLMKRHAILRTNFHAGWGDFPIQIVFKERACDFVYEDLHELES 4635 Query: 3647 SEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVYQMLWSFHHILMDGWCIGIVLK 3706 SE A + A D+ + FDL L+R +L+T Y +LWS HHI++DGWC+ +VL+ Sbjct: 4636 SEIEARLVAYIAQDKARGFDLANEALLRVAILRTAKEHYHLLWSSHHIILDGWCMPLVLQ 4695 Query: 3707 DMLEHYKQLNAGSRPSL-ETHQYRLYLDWLASKNKEEAKVYWMQYLEDYKYKELL----- 3760 ++ E Y L P L Y Y+ WL + +EEA YW YLE Y+ + L Sbjct: 4696 EVFETYGALREQKEPELPAAASYSQYIQWLEKQGEEEASSYWRGYLEGYEQQTKLPQAFT 4755 Query: 3761 ----RKEGTSKEFRLAVLDIKLEEKVRTAVTHVASSSGITINSFFQAVWGILLSKYDNAE 3816 + E E + LD +L E++ VA +T+N+ QA WGI+L +Y+ + Sbjct: 4756 QPSAKAEAYLSEKLVFTLDAELTERLE----QVAKQHQVTMNTLMQAAWGIVLQRYNRTQ 4811 Query: 3817 DVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRLSG-KTFHELAGEIQSSFISSEQYGY 3875 DVVFG+V+SGR EI GIE M+GLFINT+PVRV+ G ++F + Q +++ Y Sbjct: 4812 DVVFGSVVSGRPAEIPGIESMIGLFINTVPVRVQAEGSESFSHVMKRQQELYLAGHAYDS 4871 Query: 3876 VPLSDIQAWSH--RDLINHVMVFENYPLDREIRDTDGQQMEYGFQIAGCEILEHTNYDFS 3933 PL +IQA S +DLI+H+MVFENYP++ + + E ++I ++ E TNYDF+ Sbjct: 4872 YPLYEIQAQSEQKQDLISHIMVFENYPVEEHLEEKIAND-EAEYKITDVQMFEQTNYDFN 4930 Query: 3934 IIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTACPQIEAGDVEVLSQEEKLK 3993 +I+ PG YNA YD+E++ ++ +L I+ V+ P I ++E+++ EEK + Sbjct: 4931 LIVLPGRSLEFLYRYNARVYDRESVERIQGHLTKILTSVSVQPAIRIDELELITPEEKSQ 4990 Query: 3994 LMNVF 3998 ++ V+ Sbjct: 4991 IIEVW 4995 Score = 662 bits (1708), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/926 (37%), Positives = 551/926 (59%), Gaps = 16/926 (1%) Query: 3084 QGTIEGPVKLTAIQKWFFEQNFAEMHHWNQSILLHNER-FDVQFIRQAFQRITEHHDALR 3142 QG + G +LT +Q+WFF +N AE HH+NQ+++L+ E+ F+ + + +++ EHHDALR Sbjct: 13 QGVVRGATRLTPVQQWFFGRNQAEPHHFNQAVMLYREQGFEEKALHHVLRKLAEHHDALR 72 Query: 3143 MVYRHTGQAGVEQSNRGLA-GELFSLEVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLL 3201 MV+R T + G E NR L GEL+SL DL + + IQ+ I+L +GPL+ Sbjct: 73 MVFRQT-EHGYEAWNRDLEEGELYSLFTADLRNESNPVAAITTLSDDIQRSINLAEGPLM 131 Query: 3202 KLGLYQTTNGDYLAIVIHHLVVDGVSWRIILDDFASCYLSLDNGEEAGLIEKSDSYQKWA 3261 KLGL+ +GD+L IVIHHLVVDGVSWRI+ +D A+ Y + G+ +K+DS++ W Sbjct: 132 KLGLFHCQDGDHLLIVIHHLVVDGVSWRILFEDIAAGYEQVIQGQALTFPQKTDSFRDWG 191 Query: 3262 EALEVYANSPKLLQELAYWTDVNRIAVPALPKDSEAGNGKIKDRYQTKTVLSEKETTNLL 3321 +AL Y+ SP++ AYW ++ + LPKD + +KD + +ET LL Sbjct: 192 DALARYSESPEIEIHRAYWRELGDQPLEQLPKDEAVESLLLKDSEMVTAEWTVEETDQLL 251 Query: 3322 RHAGDAYQTETXXXXXXXXXXXIKGWANVDRVRINMEGHGREALIQDLDITRTVGWFTST 3381 R A AYQTET + W+ + ++ +N+EGHGRE ++ ++DITRTVGWFTS Sbjct: 252 RKAHRAYQTETNDLLLAALGMAVSKWSGIGKIAVNLEGHGREPIVPNIDITRTVGWFTSQ 311 Query: 3382 YPLVLELANSHELPLHIMTTKETIRQTPNKGMGYQVLKYLTSPELRAAVDFNVMPEISFN 3441 YP++L++ N+ EL I + KE +R+ PNKG+GY +LK + S E A FN+ PEISFN Sbjct: 312 YPVILDMGNNTELSALIKSVKEGLRRIPNKGIGYGLLKTMASQE--DADSFNLQPEISFN 369 Query: 3442 YLGQFGNEASYGTFEICNTFMESTESPESHRPYAIDINAMIVGNRVEIRVDYNPGQFNEA 3501 YLGQF + + ++ S +S Y +DIN M+ + + + YN Q+ + Sbjct: 370 YLGQFDQDLQGSSLQVSPYPTGSAQSLLGESAYTLDINGMVTDGALTLTMSYNGKQYKSS 429 Query: 3502 TMSRFAELLLNSLKLIISHCTREERIQRSPSDLTYKKLTFEELDDLNRL--YPGGITDVY 3559 TM + A + SL+L++ HC +ER +PSD+ K L+ +L++L++ + G I +VY Sbjct: 430 TMKQLAGYIEESLRLLLQHCVTQERTVLTPSDVLAKGLSIADLEELSKQANHIGDIENVY 489 Query: 3560 TMTPMQESMLFHALKNKRSDAYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYK 3619 ++TPMQ+ MLFH + + AY EQ D KG S +V ++ ILRT F Sbjct: 490 SLTPMQKGMLFHDMFEPHTGAYFEQAAFDFKGSFDPTAFGHSLDAVVERHAILRTNFYSG 549 Query: 3620 KLHRPLQIVLGSSDFHLEFEDITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLK 3679 PLQ+V L +ED+ M +S++ A+++ A D+ + F+L + L+R +L Sbjct: 550 WGGEPLQVVFRHRGAKLVYEDLREMNASQREAYLKTFAAKDKAQGFNLAEDELLRVSILH 609 Query: 3680 TGDSVYQMLWSFHHILMDGWCIGIVLKDMLEHYKQLNAGSRPSL-ETHQYRLYLDWLASK 3738 T + +++LWSFHHI+MDGW + ++ +++ EHY L G P L E Y Y++WL + Sbjct: 610 TDEKSFRLLWSFHHIVMDGWRVPLITQEVFEHYFALLEGREPQLAEVQPYSRYIEWLEQQ 669 Query: 3739 NKEEAKVYWMQYLEDYKYKELLRK-EGTSKE--FRLAVLDIKLEEKVRTAVTHVASSSGI 3795 ++ A YW +YL Y+ + LL + +G +K + L+ + ++ + VA + + Sbjct: 670 DEAAAADYWSRYLAGYEQQTLLPQVDGAAKREGYVAEKLNYPVSRELTERLEKVARDAHV 729 Query: 3796 TINSFFQAVWGILLSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRLSGKT 3855 T+N Q++WG+ L +Y+ + DVV+G+V+SGR EI GI+RM+GLFINTIPVRV+ Sbjct: 730 TMNILLQSIWGVALQRYNGSRDVVYGSVVSGRPAEIPGIDRMIGLFINTIPVRVKTEENL 789 Query: 3856 -FHELAGEIQSSFISSEQYGYVPLSDIQAWS--HRDLINHVMVFENYPLDREIRDTDGQQ 3912 F L Q +++S Y PL +IQA + +DLI+H+MVFENYP++ E+ G + Sbjct: 790 PFTVLMKRQQEQYMASHMYDTYPLFEIQAQTDQKQDLISHIMVFENYPVEEEVERLGGGE 849 Query: 3913 MEYGFQIAGCEILEHTNYDFSIIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQV 3972 F+I E+LE TNYDF++I+ PG++ + YNAL YD TI ++ +L ++ Q+ Sbjct: 850 AA--FEIEEAELLEQTNYDFNLIVLPGKEMRLLFQYNALVYDPATIEQIKGHLFHLMEQI 907 Query: 3973 TACPQIEAGDVEVLSQEEKLKLMNVF 3998 P I +E+++ +E+ +++NV+ Sbjct: 908 VENPAISVEALELVTPQEREQILNVW 933 Score = 535 bits (1378), Expect = e-149, Method: Compositional matrix adjust. Identities = 326/1011 (32%), Positives = 535/1011 (52%), Gaps = 47/1011 (4%) Query: 2086 LHVEGKLDPGRMEEAFQRLVKRHEPLRTSFEL-LHDEPVQVIHDDIPFSISYSIAEDEDE 2144 ++G P + + Q L+KRH LRT+F D P+Q++ + Y + + Sbjct: 4576 FEIQGVFYPEDFKRSLQHLMKRHAILRTNFHAGWGDFPIQIVFKERACDFVYEDLHELES 4635 Query: 2145 PELVKRFIL--------PFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGISANILCN 2196 E+ R + F L L RV I+ + + ++ HHII DG ++ Sbjct: 4636 SEIEARLVAYIAQDKARGFDLANEALLRVAILRTAKEHYHLLWSSHHIILDGWCMPLVLQ 4695 Query: 2197 DLISLYSG------ENLPGLEVQYKDYTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTL 2250 ++ Y LP Y Y + L + + YW+ L L Sbjct: 4696 EVFETYGALREQKEPELPA-AASYSQYI----QWLEKQGEEEASSYWRGYLEGYEQQTKL 4750 Query: 2251 PLDFPRPPV--QSFDGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQ 2308 P F +P +++ TLD++LT L+ ++ + + T+ TL+ A++ I+L +Y+ Sbjct: 4751 PQAFTQPSAKAEAYLSEKLVFTLDAELTERLEQVAKQHQVTMNTLMQAAWGIVLQRYNRT 4810 Query: 2309 EDIVIGSPVAGRFNY--STNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQ 2366 +D+V GS V+GR +M+G+F+NT+ +R Q ++F + +E L Sbjct: 4811 QDVVFGSVVSGRPAEIPGIESMIGLFINTVPVRVQAEGSESFSHVMKRQQELYLAGHAYD 4870 Query: 2367 DYPFEELISKLGIERD-ISRNPVFDVMFVLQSLDLAVP----DVHLDDIRLNGYEFKNDV 2421 YP E+ ++ ++D IS VF+ V + L+ + + + D+++ F+ Sbjct: 4871 SYPLYEIQAQSEQKQDLISHIMVFENYPVEEHLEEKIANDEAEYKITDVQM----FEQTN 4926 Query: 2422 AKFDLILEVIENTENLTLNFEYCAKLFQESTIIRMSERFLRILTTVVENCNVLLSDIDLL 2481 F+LI + +L + Y A+++ ++ R+ +ILT+V + + +++L+ Sbjct: 4927 YDFNLI---VLPGRSLEFLYRYNARVYDRESVERIQGHLTKILTSVSVQPAIRIDELELI 4983 Query: 2482 PKEETDRLIYTFNDTATAYPGGKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQ 2541 EE ++I + DTA YP KT++ +FEE+AA TP AL+ +TY +++ N+ Sbjct: 4984 TPEEKSQIIEVWGDTAAPYPREKTLHGIFEEKAALTPDHTALIFGETELTYGELHQQANR 5043 Query: 2542 MARMLRSKGVKPDTTVGILMEHSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSN 2601 +AR LR++GV+PD VGI++E S E+II + A++KAGGAYVPIDP +P +RI +++DS Sbjct: 5044 LARTLRAQGVRPDQPVGIMVERSLEMIIGIHAILKAGGAYVPIDPEFPEDRIRHMLEDSG 5103 Query: 2602 LEIMLTHKGLAEKCQFQGEFIDAASSKWYCGDDSNPVSVNSPDDLAYIIYTSGSTGLPKG 2661 +++LT L ++ F G + + Y DDSN + P+ LAYIIYTSGSTG PKG Sbjct: 5104 AKLLLTKSHLIDRFPFTGTILALDDPQAYHADDSNLEPIAGPEHLAYIIYTSGSTGKPKG 5163 Query: 2662 VMTRHQGLTNYVWWGDKTYVHGEAVDFPLYSSIAFDLSVTLIYIPLI-SGNKVFIYSGVS 2720 VM H+ + + + Y F L ++ FD SV ++ G V + GV Sbjct: 5164 VMIEHRSAVHTLSQLEAEYPMLAGDRFLLKTTFTFDFSVPELFCWFFGQGTLVILPQGVD 5223 Query: 2721 YE--SLLEAVVIDNQVDFIMLTPSHLKILGEY----DLSRLKIRKFIIG-GEAFDPFYAK 2773 + +LLEAV N++ + L PS L +L +Y K++ GE + Sbjct: 5224 KDPVALLEAVDT-NRITHLNLVPSMLSVLVQYLKESSTQGFPTLKYLFACGETLPAKLVE 5282 Query: 2774 KFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVDQNGKL 2833 +++ +++ + N+YGPTE V T Y P+ VPIG P NVQ++++D +L Sbjct: 5283 EYY-KVSPYAVLENIYGPTEAAVYATRYTTSPETAALTHVPIGKPYANVQVWMMDSAAQL 5341 Query: 2834 QGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFL 2893 +G+PGELCIAG+GV+RGY N+ +LT EKF+P P++ +YRTGDL R L DGN+E+L Sbjct: 5342 SPVGVPGELCIAGEGVARGYFNQPDLTAEKFIPHPYKPGERIYRTGDLARWLPDGNIEYL 5401 Query: 2894 GRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVIISTGPTDSRYLCAYYTADFPMNXXX 2953 GR+D QVKIRG+RIELGE+E Q++K P V +A V+ + S LCAY+ A+ + Sbjct: 5402 GRIDHQVKIRGYRIELGEVEAQILKVPSVQEAVVLALADSSGSTQLCAYFVAEEGLAAGV 5461 Query: 2954 XXXXXXXXXPRHMVPSFFVQMKSIPLTASGKVDRKKLPDSFESFQMEDAYSAPQNFIEEK 3013 P +M+PS F+Q+ +PL +GK+DRK LP + Y AP+ E + Sbjct: 5462 LREALASELPSYMIPSAFIQLGQMPLNPNGKLDRKALPAPETLLRSTAEYIAPRTQTEVE 5521 Query: 3014 LALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIVSRLKK-YGLSLEVKELF 3063 LA +W EVLG+ ++G + F +LGG S+K + ++ R+ G+ L ++ +F Sbjct: 5522 LAQIWSEVLGVQEIGIRDHFFELGGHSLKVLGLIQRISSGMGVHLPLQAVF 5572 Score = 506 bits (1303), Expect = e-140, Method: Compositional matrix adjust. Identities = 370/1252 (29%), Positives = 611/1252 (48%), Gaps = 79/1252 (6%) Query: 2079 AYNITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSF-ELLHDEPVQVIHDDIPFSISYS 2137 AY +G DP + +V+RH LRT+F EP+QV+ + Y Sbjct: 510 AYFEQAAFDFKGSFDPTAFGHSLDAVVERHAILRTNFYSGWGGEPLQVVFRHRGAKLVYE 569 Query: 2138 IAEDEDEPE---LVKRFILP-----FSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGI 2189 + + + +K F F+L + L RV I+ + ++ HHI+ DG Sbjct: 570 DLREMNASQREAYLKTFAAKDKAQGFNLAEDELLRVSILHTDEKSFRLLWSFHHIVMDGW 629 Query: 2190 SANILCNDLI----SLYSGENLPGLEVQ-YKDYTALHNEMLSNERIRQQGEYWQQLLSDD 2244 ++ ++ +L G EVQ Y Y E L + +YW + L+ Sbjct: 630 RVPLITQEVFEHYFALLEGREPQLAEVQPYSRYI----EWLEQQDEAAAADYWSRYLAGY 685 Query: 2245 IPSLTLPLDFPRPPVQSFDGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSK 2304 LP + + + + +LT L+ ++ T+ LL + + + L + Sbjct: 686 EQQTLLPQVDGAAKREGYVAEKLNYPVSRELTERLEKVARDAHVTMNILLQSIWGVALQR 745 Query: 2305 YSNQEDIVIGSPVAGRFNY--STNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEA 2362 Y+ D+V GS V+GR + M+G+F+NT+ +R + ++ F + +E + + Sbjct: 746 YNGSRDVVYGSVVSGRPAEIPGIDRMIGLFINTIPVRVKTEENLPFTVLMKRQQEQYMAS 805 Query: 2363 FENQDYPFEELISKLGIERD-ISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYEFKN-- 2419 YP E+ ++ ++D IS VF+ V + ++ RL G E Sbjct: 806 HMYDTYPLFEIQAQTDQKQDLISHIMVFENYPVEEEVE-----------RLGGGEAAFEI 854 Query: 2420 ------DVAKFDLILEVIENTENLTLNFEYCAKLFQESTIIRMSERFLRILTTVVENCNV 2473 + +D L V+ E + L F+Y A ++ +TI ++ ++ +VEN + Sbjct: 855 EEAELLEQTNYDFNLIVLPGKE-MRLLFQYNALVYDPATIEQIKGHLFHLMEQIVENPAI 913 Query: 2474 LLSDIDLLPKEETDRLIYTFNDTATAYPGGKTVYQLFEEQAARTPGAVALVHQGESITYE 2533 + ++L+ +E ++++ + DT + T + L E QA RTP A A+V + E +TY Sbjct: 914 SVEALELVTPQEREQILNVWGDTGASSKHRTTFHGLLEVQAGRTPDATAIVFENEVLTYA 973 Query: 2534 HFNRKTNQMARMLRSKGVKPDTTVGILMEHSFELIISMFAVMKAGGAYVPIDPTYPSERI 2593 N K N +AR LR++G+K VG+++E S ++I+ M+ +MKAGGAYVPIDP YP ERI Sbjct: 974 ELNAKANGLARRLRAEGIKTGDLVGLIVERSTDMIVGMYGIMKAGGAYVPIDPEYPKERI 1033 Query: 2594 NFIIKDSNLEIMLTHKGLAEKCQFQGEFIDAASSKWYCGDDSNPVSVNSPDDLAYIIYTS 2653 N++++DS +++L L E + G + Y D SN PDDLAY+IYTS Sbjct: 1034 NYMLEDSGTKMILAQAHLLEHRGWTGNVLLLDEPSTYDADASNLKDTADPDDLAYVIYTS 1093 Query: 2654 GSTGLPKGVMTRHQGLTNY--VWWG-DKTYVHGEAVDFPLYSSIAFDLSVTLIYIPLISG 2710 G+TG PKGV+ H+GL N V+ G + V F +S++FD SV+ I L G Sbjct: 1094 GTTGRPKGVLVEHRGLQNLSDVYRGLFEVTPQDRIVQF---ASLSFDASVSEILTTLSHG 1150 Query: 2711 NKVFIYSG--VSYESLLEAVVIDNQVDFIMLTPSHLKILGEYDLSRLKIRKFIIGGEAFD 2768 + I S + +L E + D + L P++ L L L R + G A Sbjct: 1151 ATLCIPSTQEILDHALFEQFMNDKGITVATLPPAYAIHLEPERLPTL--RCLLTAGSA-- 1206 Query: 2769 PFYAKKFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVD 2828 + + + + V+ +N YGPTE +V T + ++ V IG PI N ++Y++D Sbjct: 1207 --TSVELIEKWRKHVQYFNAYGPTEDSVCTTIWNAQNSEETVGIVSIGQPIANHRVYILD 1264 Query: 2829 QNGKLQGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPFQTSGMMYRTGDLVRMLQDG 2888 ++ +L +G+ GELCI+G G++RGY NR EL EKFV +P+ MYRTGDLVR L +G Sbjct: 1265 EHFRLLPVGVAGELCISGIGLARGYHNRPELMDEKFVDNPYAPGERMYRTGDLVRWLSNG 1324 Query: 2889 NVEFLGRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVIISTGPTDSRYLCAYYTADFP 2948 +E+LGR+D QVKIRG+RIELGE+E +++ P V + V+ + L AY+ A Sbjct: 1325 TIEYLGRIDHQVKIRGYRIELGEVEAHMLRVPSVQEVVVLAVESDDGYKDLVAYFVAAQK 1384 Query: 2949 MNXXXXXXXXXXXXPRHMVPSFFVQMKSIPLTASGKVDRKKLPDSFESFQMEDAYSAPQN 3008 + P +M+PS F+Q++ +PLT++GK+DRK L D E + AP+ Sbjct: 1385 LEVSELRADLSEMLPGYMIPSRFIQLEDMPLTSNGKIDRKALQD--ERGWAATSSEAPKT 1442 Query: 3009 FIEEKLALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIVSRLKK-YGLSLEVKELFLHQN 3067 IE +LA +W+EVLG+ G ++F GG S++A +VSR++K + ++E+F Sbjct: 1443 PIEIQLAEIWQEVLGVESAGVKDNFFHFGGHSLRAALLVSRIRKEMNREISLREVFGSPT 1502 Query: 3068 IKG----ISPFVKQNIKRHNQGTIEGPVKLTAIQKWFF---EQNFAEMHHWNQSILLHNE 3120 I+G I + N + L++ QK F + E+ + IL Sbjct: 1503 IEGLARAIEGYTPLNFEEIPTAEARKHYPLSSAQKRLFILSQLEGGELSYNMPGILTVEG 1562 Query: 3121 RFDVQFIRQAFQRITEHHDALRMVYRHTGQAGVEQSNRGLAGELFSLEVTDLTGCDDHTD 3180 + + + QAF+R+ H +LR + V+Q L F++E +L+ + Sbjct: 1563 DLNRERLEQAFRRLIRRHGSLRTRFVTVNGEPVQQI---LPDVPFTVEYAELSESE---- 1615 Query: 3181 LMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDYLAIV-IHHLVVDGVSWRIILDDFASCY 3239 A ++ + DL + PLL++GL + + +L + +HH+V DGVS I++++F Y Sbjct: 1616 -AEATLQQFVRPFDLGEAPLLRVGLIRIAHERHLLLFDMHHIVSDGVSMNILIEEFLRFY 1674 Query: 3240 LSLDNGEEAGLIEKSDSYQKWAEALEVYANSPKLLQELAYWTDVNRIAVPAL 3291 EE L Y +A + +L + AYW D R ++P L Sbjct: 1675 -----QEEDVLPALQIQYADYAVWQQEQLGRERLKAQEAYWLDAFRGSLPVL 1721 Score = 140 bits (353), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 111/444 (25%), Positives = 200/444 (45%), Gaps = 26/444 (5%) Query: 1310 GYQPKPLPSGPARESLTRAPQVLKLTEEQQQISLVIHSNDTHGVVHHETVG-LYLRGELN 1368 GY P P E+ P L+ Q++ L I S G + + G L + G+LN Sbjct: 1512 GYTPLNFEEIPTAEARKHYP----LSSAQKR--LFILSQLEGGELSYNMPGILTVEGDLN 1565 Query: 1369 KAALETAYHKVLNRHESLRS---TISADGNEQIVASHANADIFFADILADYSALGDEAIN 1425 + LE A+ +++ RH SLR+ T++ + +QI+ D+ F +Y+ L E+ Sbjct: 1566 RERLEQAFRRLIRRHGSLRTRFVTVNGEPVQQILP-----DVPFT---VEYAELS-ESEA 1616 Query: 1426 QALLKENAAAFDSVMGPLIRLRVLATARHEYLLALSAHHIIADGWSLIVFLQELAALYST 1485 +A L++ FD PL+R+ ++ A +LL HHI++DG S+ + ++E Y Sbjct: 1617 EATLQQFVRPFDLGEAPLLRVGLIRIAHERHLLLFDMHHIVSDGVSMNILIEEFLRFYQE 1676 Query: 1486 ECTGTRSLLPT-PTPFSDYAIWQKRMLESQPKEKAAAYWKNKFSVQTPAFELPSFRIRDA 1544 E +LP ++DYA+WQ+ L + + AYW + F P + P +R A Sbjct: 1677 E-----DVLPALQIQYADYAVWQQEQLGRERLKAQEAYWLDAFRGSLPVLDSPVDEVRPA 1731 Query: 1545 AGVRKGSRHRYVLDIPLTAKLKAVSQSMKVSLFTVLLSAYKVLLYRISNHKELVVGIPTA 1604 G R + +D L+A L+ ++ +LF VLL+AY LL++ + ++++VG P Sbjct: 1732 VRSFAGDRIDFQIDASLSASLQELATRTGSTLFMVLLAAYTTLLHKYTGQEDVIVGSPVP 1791 Query: 1605 GQMQMGQKHLVGYCLNILPFSTTINPEMTFRXXXXXXXXXXXXXXXXQDYSYASLMKELH 1664 G+ + L+G + + T E +F QDY L+++L Sbjct: 1792 GRSHATLEGLIGMFVGTVAMRTYPEGEKSFEAYLQEVKETALRAYENQDYPLEELVEKLQ 1851 Query: 1665 SLDGSVHPPQINTMFNMDKSLE-TPDFTGMDVELLQSPVSYSKYDLSMNIVELDHELMID 1723 P +T F + + + + G+ +K+DL++ + E D L Sbjct: 1852 LQRDLSRNPLFDTTFVLQNTEQGEQEIEGLRFTPYDHVHPAAKFDLTLTVSEADGTLNCT 1911 Query: 1724 FEYDPNLFDTQIITGWANYFNRIL 1747 EY ++ + A +F +++ Sbjct: 1912 LEYATAIYKRETAERMAGHFVQLI 1935 Score = 126 bits (316), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 138/550 (25%), Positives = 242/550 (44%), Gaps = 56/550 (10%) Query: 1801 ILDKDMHPSPVGVPGEVYLA-------RLTEPSLLAEQ----PSTS------TGIMAMYT 1843 ILD+ + P+GV GE+Y+A L P L AE+ P + TG +A Sbjct: 3814 ILDEQLRLVPLGVEGEMYIAGDGVARGYLNRPDLTAEKFIRNPFAAEGNMYRTGDLARRL 3873 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKILAY- 1902 + +I+ IG + G I L I+ +L+ PL+ A V Q+ + AY Sbjct: 3874 PNGDIEYIGRIDHQVKIRGYRIELGEIEAKLLDMPLVEEALVVAWADANGQK--SLCAYF 3931 Query: 1903 ITPRGTSIPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKALR 1962 + R S V E++ L + +P IPS F+ +D +PL G ++ + LP + Sbjct: 3932 VADREMS---VSELRNELSAELPAYMIPSYFVQMDVMPLTPNGKLDRKALPEPNVGVKAG 3988 Query: 1963 EEIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDISL 2022 P + E LA IW+ VL + LV +D+FFELGG+S+K S+ S + + Sbjct: 3989 AAFAAPRTDVENILASIWQGVLGVPLVGIHDNFFELGGDSIK-SIQVSSRLLHAGYKLEM 4047 Query: 2023 RMLFEHPTVKGLAKAINGAGKSFLPEITPLGKKDWYPQSSSQKRLFAIEQMGGAGTAYNI 2082 + LF +PT+ LA+ ++ + I + + +R F +E+ +N Sbjct: 4048 KDLFSYPTIAELAQRVSAVSR-----IADQSEVHGTVKLGPARRRF-LEEQSTDLHHFNQ 4101 Query: 2083 TGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFELLHDEPVQVIHDDIPFSISYSIA--- 2139 + +L+ + + + Q++ + H+ LR F + V+ + + YS+ Sbjct: 4102 SVMLYRREGFNTDALAKVIQKIAEHHDALRLVFR-QGEHGVEAWNRSLGEGELYSLQIHD 4160 Query: 2140 -EDEDEP--------ELVKRFILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGIS 2190 DE +P E ++R I SL PLFR+ + ++ EH++I+ +HH+ DG+S Sbjct: 4161 LRDEKDPALAIEAGAEAIQRSI---SLEDGPLFRLGLFRCTEGEHLLII-IHHLAVDGVS 4216 Query: 2191 ANILCNDLISLYS----GE--NLPGLEVQYKDYTALHNEMLSNERIRQQGEYWQQLLSDD 2244 IL DL Y GE LP Y+ + + ++ Q+ +W ++ + Sbjct: 4217 WRILFEDLQEGYEQAARGEAVKLPQKTDSYRAWVDGITQYANSPAAEQERSFWAEVEGEG 4276 Query: 2245 IPSLTLPLDFPRPPVQSFDGACYSVTLDSDLTRGLKVLSNR-LKTTLYTLLLASYNILLS 2303 LP D + D +VT ++ T +NR T + LLL + + + Sbjct: 4277 FA--LLPKDKVDGALLIKDSEAVTVTWSAEETEQFLKEANRTYNTEVNDLLLTALGMAVQ 4334 Query: 2304 KYSNQEDIVI 2313 +++ E + I Sbjct: 4335 EWTGIERVGI 4344 Score = 103 bits (258), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 81/258 (31%), Positives = 122/258 (47%), Gaps = 27/258 (10%) Query: 1801 ILDKDMHPSPVGVPGEVYLA-------RLTEPSLLAEQ-------PSTS---TGIMAMYT 1843 ++D SPVGVPGE+ +A +P L AE+ P TG +A + Sbjct: 5334 MMDSAAQLSPVGVPGELCIAGEGVARGYFNQPDLTAEKFIPHPYKPGERIYRTGDLARWL 5393 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTV--KPSGTFQRDQKILA 1901 D I+ +G + G I L ++ Q++ P + A V SG+ Q + A Sbjct: 5394 PDGNIEYLGRIDHQVKIRGYRIELGEVEAQILKVPSVQEAVVLALADSSGSTQ----LCA 5449 Query: 1902 Y-ITPRGTSIPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKA 1960 Y + G + +RE L S +P IPSAF+ L ++PLN G ++ + LPA + Sbjct: 5450 YFVAEEGLAAGVLREA---LASELPSYMIPSAFIQLGQMPLNPNGKLDRKALPAPETLLR 5506 Query: 1961 LREEIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDI 2020 E + P +TE LA+IW VL ++ + D FFELGG+SLK L I + Sbjct: 5507 STAEYIAPRTQTEVELAQIWSEVLGVQEIGIRDHFFELGGHSLKVLGLIQRISSGMGVHL 5566 Query: 2021 SLRMLFEHPTVKGLAKAI 2038 L+ +F PTV+ +A I Sbjct: 5567 PLQAVFNLPTVEEMAHEI 5584 Score = 100 bits (249), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 76/299 (25%), Positives = 140/299 (46%), Gaps = 14/299 (4%) Query: 1333 KLTEEQQQISLVIHSN-DTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRSTIS 1391 KLT Q+ ++ HS + H V+ E ++G + + ++ RH LR+ Sbjct: 4549 KLTPMQK--GMLFHSLLEPHSEVYFEQATFEIQGVFYPEDFKRSLQHLMKRHAILRTNFH 4606 Query: 1392 ADGNE---QIVASHANADIFFADILADYSALGDEAINQALLKENAAAFDSVMGPLIRLRV 1448 A + QIV D + D+ S+ + + + ++ A FD L+R+ + Sbjct: 4607 AGWGDFPIQIVFKERACDFVYEDLHELESSEIEARLVAYIAQDKARGFDLANEALLRVAI 4666 Query: 1449 LATARHEYLLALSAHHIIADGWSLIVFLQELAALYSTECTGTRSLLPTPTPFSDYAIWQK 1508 L TA+ Y L S+HHII DGW + + LQE+ Y LP +S Y W Sbjct: 4667 LRTAKEHYHLLWSSHHIILDGWCMPLVLQEVFETYGALREQKEPELPAAASYSQYIQW-- 4724 Query: 1509 RMLESQPKEKAAAYWKNKFSVQTPAFELPSFRIRDAAGVRK--GSRHRYVLDIPLTAKLK 1566 LE Q +E+A++YW+ +LP + +A + + LD LT +L+ Sbjct: 4725 --LEKQGEEEASSYWRGYLEGYEQQTKLPQAFTQPSAKAEAYLSEKLVFTLDAELTERLE 4782 Query: 1567 AVSQSMKVSLFTVLLSAYKVLLYRISNHKELVVGIPTAGQMQM--GQKHLVGYCLNILP 1623 V++ +V++ T++ +A+ ++L R + +++V G +G+ G + ++G +N +P Sbjct: 4783 QVAKQHQVTMNTLMQAAWGIVLQRYNRTQDVVFGSVVSGRPAEIPGIESMIGLFINTVP 4841 Score = 89.0 bits (219), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 73/294 (24%), Positives = 123/294 (41%), Gaps = 15/294 (5%) Query: 1349 DTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRSTI-SADGNE--QIVASHANA 1405 + H + E +G + A + V+ RH LR+ S G E Q+V H A Sbjct: 505 EPHTGAYFEQAAFDFKGSFDPTAFGHSLDAVVERHAILRTNFYSGWGGEPLQVVFRHRGA 564 Query: 1406 DIFFADILADYSALGDEAINQALLKENAAAFDSVMGPLIRLRVLATARHEYLLALSAHHI 1465 + + D+ ++ + + K+ A F+ L+R+ +L T + L S HHI Sbjct: 565 KLVYEDLREMNASQREAYLKTFAAKDKAQGFNLAEDELLRVSILHTDEKSFRLLWSFHHI 624 Query: 1466 IADGWSLIVFLQELAALYSTECTGTRSLLPTPTPFSDYAIWQKRMLESQPKEKAAAYWKN 1525 + DGW + + QE+ Y G L P+S Y W LE Q + AA YW Sbjct: 625 VMDGWRVPLITQEVFEHYFALLEGREPQLAEVQPYSRYIEW----LEQQDEAAAADYWSR 680 Query: 1526 KFSVQTPAFELPSFRIRDAAGVRKG---SRHRYVLDIPLTAKLKAVSQSMKVSLFTVLLS 1582 + LP D A R+G + Y + LT +L+ V++ V++ +L S Sbjct: 681 YLAGYEQQTLLPQV---DGAAKREGYVAEKLNYPVSRELTERLEKVARDAHVTMNILLQS 737 Query: 1583 AYKVLLYRISNHKELVVGIPTAGQMQM--GQKHLVGYCLNILPFSTTINPEMTF 1634 + V L R + +++V G +G+ G ++G +N +P + F Sbjct: 738 IWGVALQRYNGSRDVVYGSVVSGRPAEIPGIDRMIGLFINTIPVRVKTEENLPF 791 Score = 82.4 bits (202), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 75/312 (24%), Positives = 134/312 (42%), Gaps = 15/312 (4%) Query: 1331 VLKLTEEQQQISLVIHSN-DTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRST 1389 V KLT Q+ ++ HS + + E LRG + ++ + RH LR+ Sbjct: 3034 VYKLTAMQK--GMLFHSLLEPDSSSYFEQASFELRGSFDVDTFFESFQALAQRHAILRTG 3091 Query: 1390 IS---ADGNEQIVASHANADIFFADILADYSALGDEAINQALLKENAAAFDSVMGPLIRL 1446 D Q+V + + D+ A + I ++ A F PL R+ Sbjct: 3092 FYNNITDVPLQVVFKQRPIPLNYVDLRAATLEEQEAQIQAYTTEDMAKGFSLSEDPLTRV 3151 Query: 1447 RVLATARHEYLLALSAHHIIADGWSLIVFLQELAALYSTECTGTRSLLPTPTPFSDYAIW 1506 VL +L+ S HHI+ DGW + + QEL YS + +LP P+S Y W Sbjct: 3152 TVL-QKEQSHLVLWSFHHIVMDGWCIPIITQELFDYYSAPRQQVQPVLPPAQPYSRYIEW 3210 Query: 1507 QKRMLESQPKEKAAAYWKNKFSVQTPAFELPSFRIRDAAGVRKGSRHRYVLDI--PLTAK 1564 L++Q ++A+ YW LP + + A + +VL + LT K Sbjct: 3211 ----LDAQDDQEASTYWSQYLEDYDGNTVLPEAKTKSQAKEEGYVLNEHVLHLGTALTRK 3266 Query: 1565 LKAVSQSMKVSLFTVLLSAYKVLLYRISNHKELVVGIPTAGQMQ--MGQKHLVGYCLNIL 1622 + V++ V++ T++ +A+ ++L R + ++V G +G+ G +++VG +N + Sbjct: 3267 MDVVAKRNHVTVNTLMQTAWGLILQRYNASSDVVFGGVVSGRPAEIAGIENMVGLFINTV 3326 Query: 1623 PFSTTINPEMTF 1634 P + + F Sbjct: 3327 PIRVQSSKDEAF 3338 >C3H9Z8.1 C3H9Z8_BACTU Glutamate racemase Length = 5273 Score = 1569 bits (4063), Expect = 0.0, Method: Compositional matrix adjust. Identities = 856/2241 (38%), Positives = 1324/2241 (59%), Gaps = 60/2241 (2%) Query: 1801 ILDKDMHPSPVGVPGEVY-----LAR--LTEPSLLAEQ--PST--------STGIMAMYT 1843 IL++ P+GVPGE+ LAR L P L AE+ P+ TG + Sbjct: 2446 ILNESNGLCPLGVPGELCISGEGLARGYLNRPELTAEKFIPNPFIPGERMYRTGDLVRML 2505 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKILAYI 1903 D I+ +G + G I L I+ QL+ H + A V + Q + AY Sbjct: 2506 PDGNIEFLGRIDHQVKIRGFRIELGEIESQLLKHKEVKEAVVIAREDNN--NHQYLCAYF 2563 Query: 1904 TPRGTS-IPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFD-EDKAL 1961 T + +V+EI+KFL +P IP+ F+ LD++PL + G ++ + LP+ D A Sbjct: 2564 TSETSKGETRVQEIRKFLTKELPEYMIPAFFVQLDKLPLTTNGKVDRKALPSPDGSSVAG 2623 Query: 1962 REEIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDIS 2021 E P N EE+L IW+++L++E + +FFE+GG+SLKA+ + I KE +I Sbjct: 2624 VVEYEAPRNTVEEKLVSIWQDILDIENIGIQHNFFEIGGHSLKATTMVSRIHKELMVEIP 2683 Query: 2022 LRMLFEHPTVKGLAKAINGAGKSFLPEITPLGKKDWYPQSSSQKRLFAIEQMGGAGTAYN 2081 L +F+ PT+K + + IN +S I + ++D+YP SS+Q+RL+ + ++ G+G +YN Sbjct: 2684 LGQIFQVPTIKEIGEFINSTKESVYASIKKVEEQDYYPLSSAQRRLYILNKIEGSGVSYN 2743 Query: 2082 ITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFELLHDEPVQVIHDDIPFSISYSIAED 2141 + + ++G LD ++E+AF++L++RHE LRTSF ++ EPVQ I DI ++Y Sbjct: 2744 MPFAMKIKGDLDVHQLEQAFRKLIERHESLRTSFVMVDGEPVQKIKKDINSQVTYREMGT 2803 Query: 2142 EDEPELVKRFILPFSLNQAPLFRVHIVSRSDHEHIVIMDMHHIIADGISANILCNDLISL 2201 +++ F+ PF L +APL RV I+ +D EH++++DMHHII+DG+S I +L L Sbjct: 2804 NKLDDIINGFVKPFDLEKAPLLRVEIIHVTDDEHVMVLDMHHIISDGVSMGIFMQELAEL 2863 Query: 2202 YSGENLPGLEVQYKDYTALHNEMLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQS 2261 Y+G+ L L +QYKDY+ + + E I +Q +YW + ++++P L +P D+ RP +S Sbjct: 2864 YNGQKLSPLSIQYKDYSEWQRGLFTQEEITKQEKYWMNVFNEEVPVLNMPTDYKRPKRRS 2923 Query: 2262 FDGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRF 2321 F G ++ ++S+ L L+ + T+Y L+LA Y LLSKYS QEDIV+GSP+AGR Sbjct: 2924 FAGDRINLKINSETYNQLNKLATENEVTMYMLMLAGYTTLLSKYSGQEDIVVGSPIAGRK 2983 Query: 2322 NYSTNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIER 2381 + NN++GMFVNTLAMRN P +++F+E+L EVKENTL+A+ENQDY FEEL+ K+ + R Sbjct: 2984 HVDLNNVMGMFVNTLAMRNYPKGNRSFREYLKEVKENTLKAYENQDYQFEELVEKVNVRR 3043 Query: 2382 DISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYEFKNDVAKFDLILEVIENTENLTLNF 2441 DISRNP+FD M V Q D + ++LD ++++ E + ++ KFD+ + V E L L Sbjct: 3044 DISRNPLFDTMLVFQHTDNML--LNLDGLKVSMLEDQREIVKFDITIHVSELEHGLGLEI 3101 Query: 2442 EYCAKLFQESTIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYP 2501 EYC L+++ TI R E F+ +L VVEN LS+ID+L ++E +L+ FN+T Y Sbjct: 3102 EYCTALYKKETIERFLEHFINVLREVVENPEQKLSEIDILTEKEKSKLLNEFNNTKGKYA 3161 Query: 2502 GGKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILM 2561 KT+ +LFEEQ +TP VALV + +SITY+ N + N +A +LR KGV PD GI++ Sbjct: 3162 KEKTLPELFEEQVEKTPNNVALVFENQSITYKELNERANSLAHILREKGVGPDVVTGIMV 3221 Query: 2562 EHSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEF 2621 E S E+I+ + ++KAGGAY+PIDPTYP R +++++S++EI+ + F+G+ Sbjct: 3222 ERSIEMIVGIMGILKAGGAYLPIDPTYPRTRKEYMLRNSHIEILCVTNEVHSDISFRGQI 3281 Query: 2622 IDAASSKWYCGDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYV 2681 I K Y + +N +NSP +LAY+IYTSGSTG PKGVM + N V + Sbjct: 3282 IQLDKLK-YKENRTNISKINSPRNLAYVIYTSGSTGNPKGVMIEQNSVNNLVNGLNNVIY 3340 Query: 2682 H--GEAVDFPLYSSIAFDLSVTLIYIPLISGNKVFIY-SGVSYE--SLLEAVVIDNQVDF 2736 V+ L + FD SV I+ L+ G+ +F+ V + SL+E N++ Sbjct: 3341 KRFNTNVNVALLAPFIFDASVKQIFATLLLGHTLFVVPKEVCWNAMSLIEYYAT-NKIHV 3399 Query: 2737 IMLTPSHLKILGEYDL--SRLKIRKFIIGGEAFDPFYAKKFFSRLAE-DVEVYNVYGPTE 2793 TP+HL +L + L+I++FI+GGEA P+ K F + A+ + NVYGPTE Sbjct: 3400 SDATPAHLTMLSYVNKIEQELEIKEFIVGGEALTPYLIKGLFGKFADFKPNITNVYGPTE 3459 Query: 2794 TTVACTFYRYYPDKDLRNPV-PIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRG 2852 V T YR D+ + V PIG PI N +Y++D+ LQ IG+ GELC++G+G++RG Sbjct: 3460 CCVDSTSYRIEFDQISGDKVIPIGKPILNTNIYILDKGNNLQPIGVAGELCVSGEGIARG 3519 Query: 2853 YLNREELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEI 2912 YLN ELT E+F+ +PF MYRTGDL R L DGN+EFLGR+D QVKIRG+RIELGEI Sbjct: 3520 YLNNLELTAERFIENPFNNGKSMYRTGDLARWLPDGNIEFLGRIDHQVKIRGYRIELGEI 3579 Query: 2913 ENQLVKQPGVNKAAVIISTGPTDSRYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFFV 2972 E+QL + + VI ++YLCAY + ++ P +M+P FFV Sbjct: 3580 ESQLSTHQDIEETIVIAREDKESNQYLCAYIVSQKELHAREIREYLEQKLPDYMIPGFFV 3639 Query: 2973 QMKSIPLTASGKVDRKKLPDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNS 3032 ++ +PLT +GKVDRK LP+ S Y P+N +EEKL +W ++GI +G +++ Sbjct: 3640 KLDKLPLTTNGKVDRKALPEPDGSINTGVEYEEPRNEVEEKLFEIWRSIIGIEDIGINHN 3699 Query: 3033 FIKLGGDSIKAIQIVSRLKKYGLSLEVKELFLHQNIKGISPFVKQNIKRHN-QGTIEGPV 3091 F GGDSIKAIQI+SRL + GL LE+K+LF + IK + ++K+ K + G V Sbjct: 3700 FFVSGGDSIKAIQIISRLSRIGLKLEMKDLFANPKIKNLGKYIKREKKEQKVHEIVNGEV 3759 Query: 3092 KLTAIQKWFFEQNFAEMHHWNQSILLHNER-FDVQFIRQAFQRITEHHDALRMVYRHTGQ 3150 +LT IQ W+FE+N E+HH+NQS +L E FD + I + F +I EHHDALRM+Y+ + Sbjct: 3760 ELTPIQSWYFEKNQEEIHHFNQSFMLFRENGFDEKQIEEVFNKIMEHHDALRMIYKEK-E 3818 Query: 3151 AGVEQSNRGLAGELFSLEVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTTN 3210 + Q NRG LF L + D+ G ++ + ++ IQK +D+++G L+KL ++++ Sbjct: 3819 GEIIQYNRGYDKNLFDLYIHDVKGVENKEEKVYEIATNIQKEMDIKEGKLVKLCIFKSDE 3878 Query: 3211 GDYLAIVIHHLVVDGVSWRIILDDFASCYLSLDNGEEAGLIEKSDSYQKWAEALEVYANS 3270 GD+L I IHHLVVDGVSWRI+L+D + Y L+ GE+ + K+DSY+++A L+ Y+ S Sbjct: 3879 GDHLLIAIHHLVVDGVSWRILLEDLETLYSQLEKGEKLEIGFKTDSYKEFASKLKAYSVS 3938 Query: 3271 PKLLQELAYWTDVNRIAVPALPKDSEAGNGKIKDRYQTKTVLSEKETTNLLRHAGDAYQT 3330 +L++E YWT +++ V +PK E ++ L ++ TT+LLR+ AY T Sbjct: 3939 RELMKEREYWTSISKENVQFIPKKKEITKNNFENSSTVSITLDKELTTSLLRNTNRAYNT 3998 Query: 3331 ETXXXXXXXXXXXIKGWANVDRVRINMEGHGREALIQDLDITRTVGWFTSTYPLVLELAN 3390 E + ++++NMEGHGRE +I++ +I RTVGWFT+ YP++L++ N Sbjct: 3999 EINDILLTALAVGTRELTGKYKLKVNMEGHGREDVIENFEINRTVGWFTTMYPVLLDIGN 4058 Query: 3391 SHELPLHIMTTKETIRQTPNKGMGYQVLKYLTSPELRAAVDFNVMPE----ISFNYLGQF 3446 +EL +I T KET+R+ PNKG+GY VLK+L A D M E ISFNYLG+ Sbjct: 4059 ENELSTNIKTVKETLRKIPNKGIGYGVLKHL-------AKDKGFMNEEKAPISFNYLGEL 4111 Query: 3447 GNEASYGTFEICNTFMESTESPESHRPYAIDINAMIVGNRVEIRVDYNPGQFNEATMSRF 3506 + + F + T + +R +I++N+M++ + I +N +++E + Sbjct: 4112 DQDINRREFSASKWSIGETVGKKINRNTSIEMNSMVLNGELVIHTTFNKLEYSEKMIKDL 4171 Query: 3507 AELLLNSLKLIISHCTREERIQRSPSDLTYKKLTFEELDDLNRLYPGGITD-VYTMTPMQ 3565 + SL++II+HC + ++P D +T EEL+++ Y G I + +Y + MQ Sbjct: 4172 NQKYKESLEMIINHCANKVEPDQTPFDYGDINITLEELEEIKEKYNGFIIEKIYPLANMQ 4231 Query: 3566 ESMLFHALKNKRSDAYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPL 3625 + MLFHAL++K S Y EQ ++D+KG + ++L +SF I+ +++ILR F Y+ + P Sbjct: 4232 KGMLFHALEDKNSSMYFEQIVMDIKGTVDVDILEKSFNTIMRRHEILRAAFEYELVEEPR 4291 Query: 3626 QIVLGSSDFHLEFEDITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVY 3685 ++L ++ DI +K +E D++K F+L + LMR L++ Y Sbjct: 4292 HVILQDRKVGFKYYDIQDESIEQKTKFIENYLQNDKQKGFNLSEDTLMRISLIQMNQDSY 4351 Query: 3686 QMLWSFHHILMDGWCIGIVLKDMLEHYKQLNAGSRPSL-ETHQYRLYLDWLASKNKEEAK 3744 +++WS HHIL+DGWC+GI+L + + Y + G L E Y Y+ WL ++KEE Sbjct: 4352 KLVWSHHHILLDGWCLGIILGEFFDVYGRKMKGEDSHLAEPTPYSDYIRWLEEQDKEEGL 4411 Query: 3745 VYWMQYLEDYKYKELLRK-EGTSKEFRLAVLDIKLEEKVRTAVTHVASSSGITINSFFQA 3803 +W YL+ Y+ + + K E++ I+ +++ + +A+ + +T N+ QA Sbjct: 4412 AHWKSYLDGYEEQAQVPKILNKVNEYKRKEKMIEFSKEMNRNIIQLANRNQVTFNTVLQA 4471 Query: 3804 VWGILLSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRL-SGKTFHELAGE 3862 +WGILL++Y+N EDVVFG V+SGR ++EGIE MVGLFINTIP RV+L +F E+ Sbjct: 4472 IWGILLARYNNIEDVVFGTVVSGREAKVEGIEAMVGLFINTIPTRVKLEKDSSFKEVLRN 4531 Query: 3863 IQSSFISSEQYGYVPLSDIQAWS--HRDLINHVMVFENYPLDREIRDTDGQQME--YGFQ 3918 +Q I + +Y Y+ L++IQ+ R+LI+HVMVF+NY LD D+ E GF Sbjct: 4532 VQDESIENNKYNYINLAEIQSLHDLKRNLIDHVMVFQNYSLD----DSSFNHAESNTGFM 4587 Query: 3919 IAGCEILEHTNYDFSIIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTACPQI 3978 E TNY F+I+ PGE ++++ YN Y +E I +E +L + QV Sbjct: 4588 CQNIRGEEQTNYGFNIVAIPGEQLVLKLTYNEKIYPQEIIDNIEMHLKKVTEQVVLNEDK 4647 Query: 3979 EAGDVEVLSQEEKLKLMNVFN 3999 + +++++ ++E+ L+ FN Sbjct: 4648 KLNEIDIIPEKERDVLLYRFN 4668 Score = 849 bits (2193), Expect = 0.0, Method: Compositional matrix adjust. Identities = 519/1575 (32%), Positives = 847/1575 (53%), Gaps = 130/1575 (8%) Query: 1789 YGVSWDEADIFVILDKDMHPSPVGVPGEVYLARLTEPS-------------LLAEQPST- 1834 YG+ I+V L+++ PV V GE+Y+ + S +L E+ Sbjct: 1394 YGMPLANQKIYV-LNQNKQLCPVDVEGELYIGGVGVASGYINDIEKTKMSFILHEELGYI 1452 Query: 1835 -STGIMAMYTADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTF 1893 TG + D ++ +G + G + L I+ ++ + + V + Sbjct: 1453 YKTGDYGVLKEDGYVEFLGRKDSQVKIRGYRVELGEIENCIIKYKGVNKTVVI-----DY 1507 Query: 1894 QRDQK---ILAYITPRGTSIPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINER 1950 D K + A++ P E+K++L +++P IPS F +DEIPL G +N+ Sbjct: 1508 TNDNKMKSLYAFVVSDEDINP--NELKQYLQNQLPNYMIPSRFFKIDEIPLTVNGKVNKS 1565 Query: 1951 LLPAFDEDKALREEIML----PENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKAS 2006 +L ++ L E ENET+ ++ +IW++V +E + + +++E+GG+SLKA Sbjct: 1566 ILGELIKNHELDEVAATTCEESENETQAQILDIWKDVFEIENIGIDTNYYEIGGDSLKAI 1625 Query: 2007 LLAFSIQKEFSTDISLRMLFEHPTVKGLAKAI-NGAGKSFLPEITPLGKKDWYPQSSSQK 2065 + I+K + ++ + +F++ T+K L + + N I + KKD+Y S SQK Sbjct: 1626 SIVTEIKKRMNIEVPIGEIFKNDTIKVLDQYLKNSQDNHRGNRIERVSKKDYYATSPSQK 1685 Query: 2066 RLFAIEQMGGAGTAYNITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFELLHDEPVQV 2125 R++ + M AY+I L VEG+++ R+E+AF++ + RHE LRT FE+L +E VQ Sbjct: 1686 RMYMLSMMENNRGAYHIPMALLVEGEIECNRLEKAFRKFIDRHEILRTGFEVLDNELVQR 1745 Query: 2126 IHDDIPFSISYS---IAEDEDE------PELVKRFILPFSLNQAPLFRVHIVSRSDHEHI 2176 ++D + F + Y I +DE ++ K PF LN+ L R ++ +HI Sbjct: 1746 VYDKVDFDLEYQCLDIVVTDDEGLRDLTSKMCKESTKPFDLNKPSLMRAKLIKIGVEKHI 1805 Query: 2177 VIMDMHHIIADGISANILCNDLISLYSGENLPGLEVQYKDYTALHNEMLSNERIRQQGEY 2236 ++++ HHIIADG+S I N+++ LY+ +LP + +QYKDY +N + I++Q +Y Sbjct: 1806 LVVNFHHIIADGVSQGIFMNEILDLYNNLDLPKINIQYKDYVEWNNTYNQSNAIKKQEQY 1865 Query: 2237 WQQLLSDDIPSLTLPLDFPRPPVQSFDGACYSVTLDSDLTRGLKVLSNRLKTTLYTLLLA 2296 W L S L LP D+ + + +F G ++ +L+ ++ ++ +TLY L+L+ Sbjct: 1866 WLNLYSHLPSKLELPYDYRKENIDTFAGENAYFHIEKELSEQIRRVAKDTGSTLYMLMLS 1925 Query: 2297 SYNILLSKYSNQEDIVIGSPVAGRFNYSTNNMVGMFVNTLAMRNQPAKHKTFQEFLLEVK 2356 +Y+ILL KY+ + DIV+G+ +GR + N+ G+FVNT+A+RN K+F+E L +VK Sbjct: 1926 AYHILLHKYTGKTDIVVGTAASGRLHQDLQNIFGVFVNTIALRNNIDATKSFKEILEQVK 1985 Query: 2357 ENTLEAFENQDYPFEELISKLGIERDISRNPVFDVMFVLQSLDLAVPDVHLDDIRLNGYE 2416 ENT+ AFEN +Y F+ELI + ERD +RNP+FD MFVL+ L + L+ Sbjct: 1986 ENTITAFENSEYQFDELIRSIDYERDSNRNPLFDTMFVLEDAKLFTK--KQGALNLSPII 2043 Query: 2417 FKNDVAKFDLILEVIENTENLTLNFEYCAKLFQESTIIRMSERFLRILTTVVENCNVLLS 2476 F+ D AKFD+ +++ + + LN EY LF+ TI+RM+E ++ IL + N ++ ++ Sbjct: 2044 FELDNAKFDITFNILDYDDEIVLNVEYSTGLFKRDTILRMTENYINILREISGNLSISVN 2103 Query: 2477 DIDLLPKEETDRLIYTFNDTATAYPGGKTVYQLFEEQAARTPGAVALVHQGESITYEHFN 2536 ID++P+EE L+Y NDT + + +++LFEEQ RTP ++A+V + + +TY N Sbjct: 2104 KIDMIPQEEKRFLLYEHNDTNVDFSKNQLIHKLFEEQVERTPDSIAVVFEDKQLTYRELN 2163 Query: 2537 RKTNQMARMLRSKGVKPDTTVGILMEHSFELIISMFAVMKAGGAYVPIDPTYPSERINFI 2596 K+NQ+AR LR GV D VGIL+E S ++I+ + ++KAGGAY+PIDPTYP +RI +I Sbjct: 2164 EKSNQLARALRENGVGSDKIVGILLERSVDVIVGIMGILKAGGAYLPIDPTYPIDRIKYI 2223 Query: 2597 IKDSNLEIMLTHKGLAE--KCQFQGE--FIDAASSKWYCGDDSNPVSVNSPDDLAYIIYT 2652 ++DS EI+LT L C + I+ + + N +S DL Y+IYT Sbjct: 2224 LQDSQTEILLTQDKLINLVDCTEVDDISIINIHNEHLFKYGTENLRIDSSSKDLVYVIYT 2283 Query: 2653 SGSTGLPKGVMTRHQGLTNYVWWGDKTYVHGEAVDFPLYSSIAFDLSVTLIYIPLISG-- 2710 SGSTG PKGVM H L N W + E Y+SI+FD ++ +I+G Sbjct: 2284 SGSTGKPKGVMVEHHSLVNLCNWHNSFNKISETDKNASYASISFDAFAWEVFPYIIAGSE 2343 Query: 2711 ---------------NKVFIYSGVSYESLLEAVVIDNQVDFIMLTPSHLKILGEYDLSRL 2755 NK FI +S S L V + F+ML + L Sbjct: 2344 IHIINDNLKLDITKLNKYFIEKEISI-SFLPTQVCEQ---FLMLENTSL----------- 2388 Query: 2756 KIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDLRNPVPI 2815 R+ + GG+ + F K + ++ N YGPTE +V T + D +PI Sbjct: 2389 --RRLLTGGDKLNYFENKSY--------QIVNNYGPTENSVVTTSFIIENSYD---NIPI 2435 Query: 2816 GGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPFQTSGMM 2875 G PI N ++++++++ L +G+PGELCI+G+G++RGYLNR ELT EKF+P+PF M Sbjct: 2436 GKPICNTKVFILNESNGLCPLGVPGELCISGEGLARGYLNRPELTAEKFIPNPFIPGERM 2495 Query: 2876 YRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVIISTGPTD 2935 YRTGDLVRML DGN+EFLGR+D QVKIRG RIELGEIE+QL+K V +A VI + Sbjct: 2496 YRTGDLVRMLPDGNIEFLGRIDHQVKIRGFRIELGEIESQLLKHKEVKEAVVIAREDNNN 2555 Query: 2936 SRYLCAYYTADFPMNXXXXXXXX---XXXXPRHMVPSFFVQMKSIPLTASGKVDRKKLPD 2992 +YLCAY+T++ P +M+P+FFVQ+ +PLT +GKVDRK LP Sbjct: 2556 HQYLCAYFTSETSKGETRVQEIRKFLTKELPEYMIPAFFVQLDKLPLTTNGKVDRKALPS 2615 Query: 2993 -SFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIVSRL- 3050 S Y AP+N +EEKL +W+++L I +G ++F ++GG S+KA +VSR+ Sbjct: 2616 PDGSSVAGVVEYEAPRNTVEEKLVSIWQDILDIENIGIQHNFFEIGGHSLKATTMVSRIH 2675 Query: 3051 KKYGLSLEVKELFLHQNIKGISPFVKQNIKRHNQGTIEGPVKLTAIQKWF----FEQNFA 3106 K+ + + + ++F IK I F+ + ++ +K Q ++ ++ Sbjct: 2676 KELMVEIPLGQIFQVPTIKEIGEFINS-----TKESVYASIKKVEEQDYYPLSSAQRRLY 2730 Query: 3107 EMHHWNQSILLHNERF--------DVQFIRQAFQRITEHHDALRMVYRHTGQAGVEQSNR 3158 ++ S + +N F DV + QAF+++ E H++LR + V++ + Sbjct: 2731 ILNKIEGSGVSYNMPFAMKIKGDLDVHQLEQAFRKLIERHESLRTSFVMVDGEPVQKIKK 2790 Query: 3159 GLAGELFSLEVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDYLAIV- 3217 + ++ E+ G + D+++ +K DLEK PLL++ + T+ +++ ++ Sbjct: 2791 DINSQVTYREM----GTNKLDDIINGFVKP----FDLEKAPLLRVEIIHVTDDEHVMVLD 2842 Query: 3218 IHHLVVDGVSWRIILDDFASCYLSLDNGEE-AGLIEKSDSYQKWAEALEVYANSPKLLQE 3276 +HH++ DGVS I + + A Y NG++ + L + Y +W L ++ ++ Sbjct: 2843 MHHIISDGVSMGIFMQELAELY----NGQKLSPLSIQYKDYSEWQRGL---FTQEEITKQ 2895 Query: 3277 LAYWTDVNRIAVPAL 3291 YW +V VP L Sbjct: 2896 EKYWMNVFNEEVPVL 2910 Score = 567 bits (1461), Expect = e-158, Method: Compositional matrix adjust. Identities = 353/1052 (33%), Positives = 568/1052 (53%), Gaps = 56/1052 (5%) Query: 2058 YPQSSSQKRLFAIEQMGGAGTAYNITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSFEL 2117 YP ++ QK + + Y ++ ++G +D +E++F +++RHE LR +FE Sbjct: 4225 YPLANMQKGMLFHALEDKNSSMYFEQIVMDIKGTVDVDILEKSFNTIMRRHEILRAAFEY 4284 Query: 2118 -LHDEPVQVIHDDIPFSISYSIAEDED---EPELVKRFILP-----FSLNQAPLFRVHIV 2168 L +EP VI D Y +DE + + ++ ++ F+L++ L R+ ++ Sbjct: 4285 ELVEEPRHVILQDRKVGFKYYDIQDESIEQKTKFIENYLQNDKQKGFNLSEDTLMRISLI 4344 Query: 2169 SRSDHEHIVIMDMHHIIADGISANILCNDLISLYSGENLPGLEVQ------YKDYTALHN 2222 + + ++ HHI+ DG I+ + +Y G + G + Y DY Sbjct: 4345 QMNQDSYKLVWSHHHILLDGWCLGIILGEFFDVY-GRKMKGEDSHLAEPTPYSDYIRWLE 4403 Query: 2223 EMLSNERIRQQGEYWQQLLSDDIPSLTLPLDFPRPPVQSFDGACYSVTLDSDLTRGLKVL 2282 E E + +W+ L +P + V + + ++ R + L Sbjct: 4404 EQDKEEGL----AHWKSYLDGYEEQAQVPKILNK--VNEYKRKEKMIEFSKEMNRNIIQL 4457 Query: 2283 SNRLKTTLYTLLLASYNILLSKYSNQEDIVIGSPVAGRFNY--STNNMVGMFVNTLAMRN 2340 +NR + T T+L A + ILL++Y+N ED+V G+ V+GR MVG+F+NT+ R Sbjct: 4458 ANRNQVTFNTVLQAIWGILLARYNNIEDVVFGTVVSGREAKVEGIEAMVGLFINTIPTRV 4517 Query: 2341 QPAKHKTFQEFLLEVKENTLEAFENQDYPFEELISKLGIERDISRNPVFDVMFVLQSLDL 2400 + K +F+E L V++ E+ EN Y + L +++ D+ RN + VM V Q+ L Sbjct: 4518 KLEKDSSFKEVLRNVQD---ESIENNKYNYINL-AEIQSLHDLKRNLIDHVM-VFQNYSL 4572 Query: 2401 AVPDVHLDDIRLNGYEFKNDVAKFDLILEVIENT---------ENLTLNFEYCAKLFQES 2451 DD N E ++ E N E L L Y K++ + Sbjct: 4573 -------DDSSFNHAESNTGFMCQNIRGEEQTNYGFNIVAIPGEQLVLKLTYNEKIYPQE 4625 Query: 2452 TIIRMSERFLRILTTVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYPGGKTVYQLFE 2511 I + ++ VV N + L++ID++P++E D L+Y FNDT T YP KT++QLFE Sbjct: 4626 IIDNIEMHLKKVTEQVVLNEDKKLNEIDIIPEKERDVLLYRFNDTKTNYPKDKTIHQLFE 4685 Query: 2512 EQAARTPGAVALVHQGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILMEHSFELIISM 2571 EQ +TP +A+ +G +TY+ N ++NQ+AR LR KG+ +T VGI++E S E+II + Sbjct: 4686 EQVEKTPNHIAVEFEGTKMTYQELNERSNQVARWLRDKGITANTIVGIMVERSPEMIIGI 4745 Query: 2572 FAVMKAGGAYVPIDPTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEFIDAASSKWYC 2631 ++K+G AY+PIDP P +RI F+I+DS+++I+LT + E + S+ + Sbjct: 4746 MGILKSGSAYLPIDPKSPQDRIKFMIQDSDIQILLTQEKFINDSSLDVEMVSLDKSENFQ 4805 Query: 2632 GDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYVHGEAVDFPL- 2690 N +N +++AYIIYTSGSTG+PKGV+T H V D Y+ +A D L Sbjct: 4806 LSKENLAPINDSENIAYIIYTSGSTGVPKGVVTSHSNAVRVV--RDTNYIKIDADDIILQ 4863 Query: 2691 YSSIAFDLSVTLIYIPLISGNKVFIYS--GVSYESLLEAVVIDNQVDFIMLTPSHLKILG 2748 S+ +FD SV IY L++G K+ + S V S L ++ + ++ + +T + L Sbjct: 4864 LSNYSFDGSVFDIYGALLNGAKLVMVSIDTVLNLSKLTKLIKEEKISVMFITTALFNTLV 4923 Query: 2749 EYDLSRL-KIRKFIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDK 2807 + ++ L IRK + GGE + K+ L +D ++ +VYGPTE+TV T+Y Sbjct: 4924 DLEIECLSNIRKILFGGERISVSHTKRALEYLGKD-KLIHVYGPTESTVFATYYCINEIN 4982 Query: 2808 DLRNPVPIGGPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYLNREELTREKFVPD 2867 + + +PIG P+ N ++VD N +L IG+ GELC++G G++ GYLNR +LT EKFV + Sbjct: 4983 EEFDTIPIGKPLANTSAFIVDGNQRLLPIGVAGELCLSGAGLAHGYLNRPDLTAEKFVSN 5042 Query: 2868 PFQTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAV 2927 PF MYRTGDLVRML DGN+EFLGR+D QVK+RG RIELGEIE+QL+K V +A V Sbjct: 5043 PFIPEEKMYRTGDLVRMLPDGNIEFLGRIDHQVKVRGFRIELGEIESQLLKYKKVKEAIV 5102 Query: 2928 IISTGPTDSRYLCAYYTADF---PMNXXXXXXXXXXXXPRHMVPSFFVQMKSIPLTASGK 2984 I+ +Y+CAY+T++ + P +M+P+FFVQ+ +PLT +GK Sbjct: 5103 IVRDDIHGEKYICAYFTSETWKDELIIQEIRKYLTKKLPEYMIPAFFVQLDKLPLTTNGK 5162 Query: 2985 VDRKKLPDSFESFQMEDAYSAPQNFIEEKLALVWEEVLGINKVGTSNSFIKLGGDSIKAI 3044 VDRK LP + E Y AP NF+EE + +WEE+LGI +G S++F ++GG+S+K + Sbjct: 5163 VDRKSLPKPDGNVTTEVEYVAPSNFVEETIISIWEEILGIKSIGISHNFFEIGGNSLKLM 5222 Query: 3045 QIVSRLKK-YGLSLEVKELFLHQNIKGISPFV 3075 V+ + K + + F + ++ G++ ++ Sbjct: 5223 SAVAAINKVLNTDISIHNFFENPSVMGLANYI 5254 Score = 517 bits (1331), Expect = e-143, Method: Compositional matrix adjust. Identities = 444/1566 (28%), Positives = 748/1566 (47%), Gaps = 145/1566 (9%) Query: 1801 ILDKDMHPSPVGVPGEVYLAR--LTEPSLLAEQPSTS---------------TGIMAMYT 1843 I+D+ + P+G PGE+ ++ LT+ L EQ + TG +A + Sbjct: 366 IVDEKKNLLPIGEPGELCISGDGLTKGYLNNEQLTLEKFVKNPFAEGERLYRTGDLARWL 425 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKILAYI 1903 D I+ IG + G I L I+ QL+ HP + V + + I AY+ Sbjct: 426 PDGNIEFIGRIDHQVKVRGFRIELGEIESQLLKHPNVKETVVVAREEK--DKSNYICAYL 483 Query: 1904 TPRGTSIPKVREIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKALRE 1963 T G V E++KFL ++P IP+ F+ LD++PL + G I+++ LP D Sbjct: 484 TLVGEVT--VEELRKFLGEKLPDYMIPTYFLKLDKMPLTANGKIDKKSLPEPDRSFNTEV 541 Query: 1964 EIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDISLR 2023 E P +E E++L +W+ LN+ V ND F LGG+S+ A L + S D+ L+ Sbjct: 542 EYEEPRSEIEKQLVLMWQETLNINKVGINDSFAVLGGHSINAMELLSKMNDRLSVDLPLK 601 Query: 2024 MLFEHPTVKGLAKAING------AGKSFLPEITPLGKKDWYPQSSSQ-----KRLFAIEQ 2072 LF T+K ++ I + F + +P + Q R A E Sbjct: 602 ELFRLSTIKKISAYIETNKGEIIENRQFTKTTDLKNLHEPFPLTGIQLAYLIGRDPAFE- 660 Query: 2073 MGGAGTAYNITGILHVEGKLDPGRMEEAFQRLVKRHEPLRTSF-----------ELLHD- 2120 +GGA T N+T ++ +D R A Q+L+ RH LRT ELL+ Sbjct: 661 IGGAAT--NLTVEFEIDINID--RFNSALQKLINRHPILRTIVFENGTQRILEGELLYSV 716 Query: 2121 EPVQVIH---DDIPFSISYSIAEDEDEPELVKRFILPFSLNQAPLFRVHIVSRSDHEHIV 2177 + V V H +DI I E +++ + I P + PLF + +++ Sbjct: 717 DTVDVRHLNQEDIMIRIL------EQRQKMIAKIIDPSTW---PLFEIKAFILPNNQKYF 767 Query: 2178 IMDMHHIIADGISANILCNDLISLYSGEN--LPGLEVQYKDYTALHNEMLSNERIRQQGE 2235 +++ +I D S IL + Y+ + LP LE ++DY NE + R ++ + Sbjct: 768 CLNIDPLICDDSSMKILIKEFKMFYNQPSLQLPELEYNFRDYVLATNEFRQSNRYKKDEK 827 Query: 2236 YWQQLLSD--DIPSLTL---PLDFPRPPVQSFDGACYSVTLDSDLTRGLKVLSNRLKTTL 2290 YW L + P+L L PL+ +P C S L+ + LK + T Sbjct: 828 YWLNKLDNFPSAPALPLKCNPLEIEKPTFNK----C-SEFLERETWNRLKQKAREKNLTP 882 Query: 2291 YTLLLASYNILLSKYSNQEDIVIGSPVAGR--FNYSTNNMVGMFVNTLAMRNQPAKH--K 2346 ++L A+Y +L+ +SNQ + V R F+ ++G F TL + + AK + Sbjct: 883 TSVLCAAYAYVLAYWSNQSRFAVNLTVFNRIPFHQDVKKIIGDFT-TLMLLDINAKDSIE 941 Query: 2347 TFQEFLLEVKENTLEAFENQDYPFEELISKLGIERDISRNPVFDVMFV-LQSLDLAVPDV 2405 +F +F +V++ LEA E++ Y + I +G + + + ++F + S D Sbjct: 942 SFWKFAAKVQDTLLEALEHRHYDGVDFIRAIGKKHRMVNQAIMPIVFTSVLSEDSDDSFN 1001 Query: 2406 HLDDIRLNGYEFKNDVAKFDLILEVIENTENLTLNFEYCAKLFQESTIIRMSERFLRILT 2465 HL D + F ++ + +V E L + ++Y +LF+ + I M E+++ +L Sbjct: 1002 HLIDFEKIKF-FSTRTSQVYIDNQVYELNGGLYITWDYVEQLFEINVIKSMFEQYINVLN 1060 Query: 2466 TVVENCNVLLSDIDLLPKEETDRLIYTFNDTATAYPGGKTVYQLFEEQAARTPGAVALVH 2525 V+ N V S I+L + + ++I T+NDT + T++++F +A P VA++H Sbjct: 1061 QVIFNDQV--SGINL--SDNSIKVIETYNDTNKKFDKC-TLHEMFVNRAKLVPDKVAVIH 1115 Query: 2526 QGESITYEHFNRKTNQMARMLRSKGVKPDTTVGILMEHSFELIISMFAVMKAGGAYVPID 2585 +SITY+ N K+NQ+AR L KGV+ +G++ + + II++FAV+KAG AY+P+D Sbjct: 1116 HDDSITYKELNEKSNQIARYLMDKGVRKGDYIGVIGKRCIDTIINLFAVLKAGAAYIPLD 1175 Query: 2586 PTYPSERINFIIKDSNLEIMLTHKGLAEKCQFQGEFIDAASSKWYCGDDSNPVSVNSPDD 2645 P YP ER +I K SN + +T ++ E I + Y GD+ N + V+ D Sbjct: 1176 PDYPEERKEYIKKKSNCKFFIT------PSTYKDENI-----REYSGDEVN-IKVDET-D 1222 Query: 2646 LAYIIYTSGSTGLPKGVMTRHQGLTNYVWWGDKTYVHGEAVDFPLYSSIAFDLSVTLIYI 2705 +AY+I+TSGSTG PKGV H TN + ++ + E SS+ FDLSV ++ Sbjct: 1223 MAYVIFTSGSTGKPKGVQITHGAATNTIIDINEKFCVTENDKIMGISSLCFDLSVYDVFG 1282 Query: 2706 PLISGNKVFIYS------GVSYESLLEAVVIDNQVDFIMLTPSHLKILGEYDLSRLKIRK 2759 L G + I + E + I N V IM L E D S +R Sbjct: 1283 ALSCGAALVIIDDQRDVYNLKKVVKKEGITIWNSVPAIMELTVDLYNDSEQDDS---LRL 1339 Query: 2760 FIIGGEAFDPFYAKKFFSRLAEDVEVYNVYGPTETTVACTFYRYYPDKDLR---NPVPIG 2816 ++ G+ P + + ++ EV ++ G TE ++ YYP K+++ +P G Sbjct: 1340 VLLSGDWI-PLELPQKIKKTFKNAEVISLGGATEGSIWSI---YYPIKEIKGDWKSIPYG 1395 Query: 2817 GPIFNVQLYVVDQNGKLQGIGIPGELCIAGDGVSRGYLNREELTREKFVPDPFQTSGMMY 2876 P+ N ++YV++QN +L + + GEL I G GV+ GY+N E T+ F+ + G +Y Sbjct: 1396 MPLANQKIYVLNQNKQLCPVDVEGELYIGGVGVASGYINDIEKTKMSFI--LHEELGYIY 1453 Query: 2877 RTGDLVRMLQDGNVEFLGRMDDQVKIRGHRIELGEIENQLVKQPGVNKAAVIISTGPTDS 2936 +TGD + +DG VEFLGR D QVKIRG+R+ELGEIEN ++K GVNK VI T Sbjct: 1454 KTGDYGVLKEDGYVEFLGRKDSQVKIRGYRVELGEIENCIIKYKGVNKTVVIDYTNDNKM 1513 Query: 2937 RYLCAYYTADFPMNXXXXXXXXXXXXPRHMVPSFFVQMKSIPLTASGKVDRKKLPDSFES 2996 + L A+ +D +N P +M+PS F ++ IPLT +GKV++ L + ++ Sbjct: 1514 KSLYAFVVSDEDINPNELKQYLQNQLPNYMIPSRFFKIDEIPLTVNGKVNKSILGELIKN 1573 Query: 2997 FQMEDAYSA----PQNFIEEKLALVWEEVLGINKVGTSNSFIKLGGDSIKAIQIVSRLKK 3052 ++++ + +N + ++ +W++V I +G ++ ++GGDS+KAI IV+ +KK Sbjct: 1574 HELDEVAATTCEESENETQAQILDIWKDVFEIENIGIDTNYYEIGGDSLKAISIVTEIKK 1633 Query: 3053 -YGLSLEVKELFLHQNIKGISPFVKQNIKRHNQGTIEGPVK-----LTAIQKWFFEQNFA 3106 + + + E+F + IK + ++K + H IE K + QK + + Sbjct: 1634 RMNIEVPIGEIFKNDTIKVLDQYLKNSQDNHRGNRIERVSKKDYYATSPSQKRMYMLSMM 1693 Query: 3107 E----MHHWNQSILLHNERFDVQFIRQAFQRITEHHDALRMVYR----HTGQAGVEQSNR 3158 E +H ++L+ E + + +AF++ + H+ LR + Q ++ + Sbjct: 1694 ENNRGAYHIPMALLVEGE-IECNRLEKAFRKFIDRHEILRTGFEVLDNELVQRVYDKVDF 1752 Query: 3159 GLAGELFSLEVTDLTGCDDHTDLMHAGIKTIQKGIDLEKGPLLKLGLYQTTNGDYLAIV- 3217 L + + VTD G D T M K K DL K L++ L + ++ +V Sbjct: 1753 DLEYQCLDIVVTDDEGLRDLTSKM---CKESTKPFDLNKPSLMRAKLIKIGVEKHILVVN 1809 Query: 3218 IHHLVVDGVSWRIILDDFASCYLSLDNGEEAGLIEKSDSYQKWAEALEVYANSPKLLQEL 3277 HH++ DGVS I +++ Y +LD L + + Y+ + E Y S + ++ Sbjct: 1810 FHHIIADGVSQGIFMNEILDLYNNLD------LPKINIQYKDYVEWNNTYNQSNAIKKQE 1863 Query: 3278 AYWTDV 3283 YW ++ Sbjct: 1864 QYWLNL 1869 Score = 484 bits (1246), Expect = e-134, Method: Compositional matrix adjust. Identities = 310/938 (33%), Positives = 486/938 (51%), Gaps = 49/938 (5%) Query: 2485 ETDRLIYTFNDTATAYPGGKTVYQLFEEQAARTPGAVALVHQGESITYEHFNRKTNQMAR 2544 E D ++ FN T YP KT+ QLFEEQ RTP +A+V + + +TY N K+NQ+AR Sbjct: 24 EQDMILNKFNSTKNEYPRNKTINQLFEEQVERTPENIAVVFKDKQLTYRQLNEKSNQLAR 83 Query: 2545 MLRSKGVKPDTTVGILMEHSFELIISMFAVMKAGGAYVPIDPTYPSERINFIIKDSNLEI 2604 MLR+KGV D +G++++ S E+II + ++K+G AY+PIDP P RI+++++DS+ I Sbjct: 84 MLRNKGVNTDAIIGLMIDRSLEMIIGIMGILKSGAAYLPIDPDTPKARIDYMLRDSHTMI 143 Query: 2605 MLTHKGLAEKCQFQGEFIDAASSKWYCGDDSNPVSVNSPDDLAYIIYTSGSTGLPKGVMT 2664 +LT + +K ++ E I+ N +N DD AYIIYTSGSTG+PKGV+ Sbjct: 144 LLTQEKFIKKIEYDLEIINLDELDSSDLSTGNLKHINRFDDTAYIIYTSGSTGIPKGVII 203 Query: 2665 RHQGLTNYVWWGDKTYVHGEAVDFPLYSSIAFDLSVTLIYIPLISGNKVFIYSGVSYESL 2724 H V + ++ L S+ +FD S+ IY L++G K+ + + + Sbjct: 204 SHYSAIRVVRNTNYIEINNNDTILQL-SNYSFDGSIFDIYGALLNGAKLVVIEKDTVTDI 262 Query: 2725 --LEAVVIDNQVDFIMLTPSHLKILGEYDLSRL-KIRKFIIGGEAFDPFYAKKFFSRLAE 2781 L ++ ++ + +T + L + + L +RK + GGE +A+K L + Sbjct: 263 NKLGNIIKQENINVMFITTALFNALVDIKIDCLINMRKILFGGERISVSHARKALEFLGK 322 Query: 2782 DVEVYNVYGPTETTVACTFYRYYPDKDLRNPVPIGGPIFNVQLYVVDQNGKLQGIGIPGE 2841 D ++ +VYGPTE+TV T+Y + + +PIG P+ N +Y+VD+ L IG PGE Sbjct: 323 D-KLIHVYGPTESTVFATYYFINEIDEDVDTLPIGKPLANTSVYIVDEKKNLLPIGEPGE 381 Query: 2842 LCIAGDGVSRGYLNREELTREKFVPDPFQTSGMMYRTGDLVRMLQDGNVEFLGRMDDQVK 2901 LCI+GDG+++GYLN E+LT EKFV +PF +YRTGDL R L DGN+EF+GR+D QVK Sbjct: 382 LCISGDGLTKGYLNNEQLTLEKFVKNPFAEGERLYRTGDLARWLPDGNIEFIGRIDHQVK 441 Query: 2902 IRGHRIELGEIENQLVKQPGVNKAAVIISTGPTDSRYLCAYYTADFPMNXXXXXXXXXXX 2961 +RG RIELGEIE+QL+K P V + V+ S Y+CAY T + Sbjct: 442 VRGFRIELGEIESQLLKHPNVKETVVVAREEKDKSNYICAYLTLVGEVTVEELRKFLGEK 501 Query: 2962 XPRHMVPSFFVQMKSIPLTASGKVDRKKLPDSFESFQMEDAYSAPQNFIEEKLALVWEEV 3021 P +M+P++F+++ +PLTA+GK+D+K LP+ SF E Y P++ IE++L L+W+E Sbjct: 502 LPDYMIPTYFLKLDKMPLTANGKIDKKSLPEPDRSFNTEVEYEEPRSEIEKQLVLMWQET 561 Query: 3022 LGINKVGTSNSFIKLGGDSIKAIQIVSRLK-KYGLSLEVKELFLHQNIKGISPFVKQN-- 3078 L INKVG ++SF LGG SI A++++S++ + + L +KELF IK IS +++ N Sbjct: 562 LNINKVGINDSFAVLGGHSINAMELLSKMNDRLSVDLPLKELFRLSTIKKISAYIETNKG 621 Query: 3079 --------IKRHNQGTIEGPVKLTAIQKWF-------FEQNFAEMHHWNQ-SILLHNERF 3122 K + + P LT IQ + FE A + + I ++ +RF Sbjct: 622 EIIENRQFTKTTDLKNLHEPFPLTGIQLAYLIGRDPAFEIGGAATNLTVEFEIDINIDRF 681 Query: 3123 DVQFIRQAFQRITEHHDALRMVYRHTGQAGVEQSNRGLAGELF----SLEVTDLTGCDDH 3178 + A Q++ H LR + G + R L GEL +++V L D Sbjct: 682 N-----SALQKLINRHPILRTIVFENG------TQRILEGELLYSVDTVDVRHLNQEDIM 730 Query: 3179 TDLMHAGIKTIQKGIDLEKGPLLKLGLY-QTTNGDYLAIVIHHLVVDGVSWRIILDDFAS 3237 ++ K I K ID PL ++ + N Y + I L+ D S +I++ +F Sbjct: 731 IRILEQRQKMIAKIIDPSTWPLFEIKAFILPNNQKYFCLNIDPLICDDSSMKILIKEFKM 790 Query: 3238 CYLSLDNGEEAGLIEKSDSYQKWAEALEVYANSPKLLQELAYWTDV--NRIAVPALPKDS 3295 Y N L E +++ + A + S + ++ YW + N + PALP Sbjct: 791 FY----NQPSLQLPELEYNFRDYVLATNEFRQSNRYKKDEKYWLNKLDNFPSAPALPLKC 846 Query: 3296 EAGNGKIKDRYQTKTVLSEKETTNLLRHAGDAYQTETXXXXXXXXXXXIKGWANVDRVRI 3355 + K + + E+ET N L+ + W+N R + Sbjct: 847 NPLEIE-KPTFNKCSEFLERETWNRLKQKAREKNLTPTSVLCAAYAYVLAYWSNQSRFAV 905 Query: 3356 NMEGHGREALIQDLDITRTVGWFTSTYPLVLELANSHE 3393 N+ R Q D+ + +G FT+ L + +S E Sbjct: 906 NLTVFNRIPFHQ--DVKKIIGDFTTLMLLDINAKDSIE 941 Score = 156 bits (395), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 101/406 (24%), Positives = 194/406 (47%), Gaps = 20/406 (4%) Query: 1352 GVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRST-ISADGNE-QIVASHANADIFF 1409 GV ++ + ++G+L+ LE A+ K++ RHESLR++ + DG Q + N+ + Sbjct: 2739 GVSYNMPFAMKIKGDLDVHQLEQAFRKLIERHESLRTSFVMVDGEPVQKIKKDINSQV-- 2796 Query: 1410 ADILADYSALGDEAINQALLKENAAAFDSVMGPLIRLRVLATARHEYLLALSAHHIIADG 1469 Y +G ++ ++ FD PL+R+ ++ E+++ L HHII+DG Sbjct: 2797 -----TYREMGTNKLDD-IINGFVKPFDLEKAPLLRVEIIHVTDDEHVMVLDMHHIISDG 2850 Query: 1470 WSLIVFLQELAALYSTECTGTRSLLPTPTPFSDYAIWQKRMLESQPKEKAAAYWKNKFSV 1529 S+ +F+QELA LY+ + L P + DY+ WQ+ + + K YW N F+ Sbjct: 2851 VSMGIFMQELAELYNGQ-----KLSPLSIQYKDYSEWQRGLFTQEEITKQEKYWMNVFNE 2905 Query: 1530 QTPAFELPSFRIRDAAGVRKGSRHRYVLDIPLTAKLKAVSQSMKVSLFTVLLSAYKVLLY 1589 + P +P+ R G R ++ +L ++ +V+++ ++L+ Y LL Sbjct: 2906 EVPVLNMPTDYKRPKRRSFAGDRINLKINSETYNQLNKLATENEVTMYMLMLAGYTTLLS 2965 Query: 1590 RISNHKELVVGIPTAGQMQMGQKHLVGYCLNILPFSTTINPEMTFRXXXXXXXXXXXXXX 1649 + S +++VVG P AG+ + +++G +N L +FR Sbjct: 2966 KYSGQEDIVVGSPIAGRKHVDLNNVMGMFVNTLAMRNYPKGNRSFREYLKEVKENTLKAY 3025 Query: 1650 XXQDYSYASLMKELHSLDGSVHPPQINTMF---NMDKSLETPDFTGMDVELLQSPVSYSK 1706 QDY + L+++++ P +TM + D L D G+ V +L+ K Sbjct: 3026 ENQDYQFEELVEKVNVRRDISRNPLFDTMLVFQHTDNMLLNLD--GLKVSMLEDQREIVK 3083 Query: 1707 YDLSMNIVELDHELMIDFEYDPNLFDTQIITGWANYFNRILLAVLQ 1752 +D+++++ EL+H L ++ EY L+ + I + +F +L V++ Sbjct: 3084 FDITIHVSELEHGLGLEIEYCTALYKKETIERFLEHFINVLREVVE 3129 Score = 139 bits (349), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 97/399 (24%), Positives = 181/399 (45%), Gaps = 18/399 (4%) Query: 1355 HHETVGLYLRGELNKAALETAYHKVLNRHESLRSTISADGNEQIVASHANADIFFADILA 1414 +H + L + GE+ LE A+ K ++RHE LR+ NE + + D Sbjct: 1700 YHIPMALLVEGEIECNRLEKAFRKFIDRHEILRTGFEVLDNELVQRVYDKVDFDLEYQCL 1759 Query: 1415 DYSALGDEAI---NQALLKENAAAFDSVMGPLIRLRVLATARHEYLLALSAHHIIADGWS 1471 D DE + + KE+ FD L+R +++ +++L ++ HHIIADG S Sbjct: 1760 DIVVTDDEGLRDLTSKMCKESTKPFDLNKPSLMRAKLIKIGVEKHILVVNFHHIIADGVS 1819 Query: 1472 LIVFLQELAALYSTECTGTRSLLPTPTPFSDYAIWQKRMLESQPKEKAAAYWKNKFSVQT 1531 +F+ E+ LY+ L + DY W +S +K YW N +S Sbjct: 1820 QGIFMNEILDLYNN-----LDLPKINIQYKDYVEWNNTYNQSNAIKKQEQYWLNLYSHLP 1874 Query: 1532 PAFELPSFRIRDAAGVRKGSRHRYVLDIPLTAKLKAVSQSMKVSLFTVLLSAYKVLLYRI 1591 ELP ++ G + ++ L+ +++ V++ +L+ ++LSAY +LL++ Sbjct: 1875 SKLELPYDYRKENIDTFAGENAYFHIEKELSEQIRRVAKDTGSTLYMLMLSAYHILLHKY 1934 Query: 1592 SNHKELVVGIPTAGQMQMGQKHLVGYCLNILPFSTTINPEMTFRXXXXXXXXXXXXXXXX 1651 + ++VVG +G++ +++ G +N + I+ +F+ Sbjct: 1935 TGKTDIVVGTAASGRLHQDLQNIFGVFVNTIALRNNIDATKSFKEILEQVKENTITAFEN 1994 Query: 1652 QDYSYASLMKELHSLDGSVHPPQINTMFNMDKSLETPDFTGMDVELLQSPVSY----SKY 1707 +Y + L++ + S P +TMF ++ + FT L SP+ + +K+ Sbjct: 1995 SEYQFDELIRSIDYERDSNRNPLFDTMFVLE---DAKLFTKKQGALNLSPIIFELDNAKF 2051 Query: 1708 DLSMNIVELDHELMIDFEYDPNLF--DTQIITGWANYFN 1744 D++ NI++ D E++++ EY LF DT I+ NY N Sbjct: 2052 DITFNILDYDDEIVLNVEYSTGLFKRDT-ILRMTENYIN 2089 Score = 121 bits (303), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 118/480 (24%), Positives = 224/480 (46%), Gaps = 47/480 (9%) Query: 3548 NRLYPGGITDVYTMTPMQESMLFHALKNKRSDAYHEQCILDLKGDIIQELLNESFKLIVG 3607 NR+ D Y +P Q+ M ++ AYH L ++G+I L ++F+ + Sbjct: 1667 NRIERVSKKDYYATSPSQKRMYMLSMMENNRGAYHIPMALLVEGEIECNRLEKAFRKFID 1726 Query: 3608 KYDILRTRFVYKKLHRPLQIVLGSSDFHLEFE--DITHMESSEKMAHMERLKALDREKRF 3665 +++ILRT F + +Q V DF LE++ DI + E + + + K F Sbjct: 1727 RHEILRTGFEVLD-NELVQRVYDKVDFDLEYQCLDIV-VTDDEGLRDLTSKMCKESTKPF 1784 Query: 3666 DLVQGPLMRAILLKTGDSVYQMLWSFHHILMDGWCIGIVLKDMLEHYKQLNAGSRPSLET 3725 DL + LMRA L+K G + ++ +FHHI+ DG GI + ++L+ Y L+ P + Sbjct: 1785 DLNKPSLMRAKLIKIGVEKHILVVNFHHIIADGVSQGIFMNEILDLYNNLDL---PKINI 1841 Query: 3726 HQYRLYLDWLASKNKEEA----KVYWMQYLEDYKYKELLRKEGTSKEFRLAVLD------ 3775 QY+ Y++W + N+ A + YW+ Y L K ++R +D Sbjct: 1842 -QYKDYVEWNNTYNQSNAIKKQEQYWLNL-----YSHLPSKLELPYDYRKENIDTFAGEN 1895 Query: 3776 --IKLEEKVRTAVTHVASSSGITINSFFQAVWGILLSKYDNAEDVVFGAVISGRSPEIEG 3833 +E+++ + VA +G T+ + + ILL KY D+V G SGR + Sbjct: 1896 AYFHIEKELSEQIRRVAKDTGSTLYMLMLSAYHILLHKYTGKTDIVVGTAASGRLH--QD 1953 Query: 3834 IERMVGLFINTIPVRVRLSG-KTFHELAGEIQSSFISS---EQYGYVPL---SDIQAWSH 3886 ++ + G+F+NTI +R + K+F E+ +++ + I++ +Y + L D + S+ Sbjct: 1954 LQNIFGVFVNTIALRNNIDATKSFKEILEQVKENTITAFENSEYQFDELIRSIDYERDSN 2013 Query: 3887 RD-LINHVMVFENYPLDREIRDTDGQQMEYGFQIAGCEILEHTNYDFSI---IIEPGEDF 3942 R+ L + + V E+ L + + ++ I E N F I I++ ++ Sbjct: 2014 RNPLFDTMFVLEDAKL--------FTKKQGALNLSPI-IFELDNAKFDITFNILDYDDEI 2064 Query: 3943 IIRIVYNALAYDKETISILESYLLAIIGQVTACPQIEAGDVEVLSQEEKLKLMNVFNKPN 4002 ++ + Y+ + ++TI + + I+ +++ I ++++ QEEK L+ N N Sbjct: 2065 VLNVEYSTGLFKRDTILRMTENYINILREISGNLSISVNKIDMIPQEEKRFLLYEHNDTN 2124 Score = 114 bits (285), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 78/256 (30%), Positives = 126/256 (49%), Gaps = 20/256 (7%) Query: 1801 ILDKDMHPSPVGVPGEVYLA-------RLTEPSLLAEQPSTS----------TGIMAMYT 1843 I+D + P+GV GE+ L+ L P L AE+ ++ TG + Sbjct: 5001 IVDGNQRLLPIGVAGELCLSGAGLAHGYLNRPDLTAEKFVSNPFIPEEKMYRTGDLVRML 5060 Query: 1844 ADFEIKVIGHHSRLMSQNGRMINLDTIQEQLVLHPLIGHAAVTVKPSGTFQRDQKILAYI 1903 D I+ +G + G I L I+ QL+ + + A V V+ ++ I AY Sbjct: 5061 PDGNIEFLGRIDHQVKVRGFRIELGEIESQLLKYKKVKEAIVIVRDD--IHGEKYICAYF 5118 Query: 1904 TPRGTSIPKV-REIKKFLLSRIPGNFIPSAFMVLDEIPLNSKGGINERLLPAFDEDKALR 1962 T + +EI+K+L ++P IP+ F+ LD++PL + G ++ + LP D + Sbjct: 5119 TSETWKDELIIQEIRKYLTKKLPEYMIPAFFVQLDKLPLTTNGKVDRKSLPKPDGNVTTE 5178 Query: 1963 EEIMLPENETEERLAEIWRNVLNLELVNTNDDFFELGGNSLKASLLAFSIQKEFSTDISL 2022 E + P N EE + IW +L ++ + + +FFE+GGNSLK +I K +TDIS+ Sbjct: 5179 VEYVAPSNFVEETIISIWEEILGIKSIGISHNFFEIGGNSLKLMSAVAAINKVLNTDISI 5238 Query: 2023 RMLFEHPTVKGLAKAI 2038 FE+P+V GLA I Sbjct: 5239 HNFFENPSVMGLANYI 5254 Score = 105 bits (262), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 101/454 (22%), Positives = 207/454 (45%), Gaps = 56/454 (12%) Query: 3580 AYHEQCILDLKGDIIQELLNESFKLIVGKYDILRTRFVYKKLHRPLQIVLGSSDFHLEFE 3639 +Y+ + +KGD+ L ++F+ ++ +++ LRT FV P+Q + + + + Sbjct: 2741 SYNMPFAMKIKGDLDVHQLEQAFRKLIERHESLRTSFVMVD-GEPVQKIKKDINSQVTYR 2799 Query: 3640 DITHMESSEKMAHMERLKALDREKRFDLVQGPLMRAILLKTGDSVYQMLWSFHHILMDGW 3699 ++ + + + K FDL + PL+R ++ D + M+ HHI+ DG Sbjct: 2800 EMGTNKLDDIINGFV--------KPFDLEKAPLLRVEIIHVTDDEHVMVLDMHHIISDGV 2851 Query: 3700 CIGIVLKDMLEHYKQLNAGSRPSLETHQYRLYLDW----LASKNKEEAKVYWMQYLE--- 3752 +GI ++++ E Y G + S + QY+ Y +W + + + YWM Sbjct: 2852 SMGIFMQELAELYN----GQKLSPLSIQYKDYSEWQRGLFTQEEITKQEKYWMNVFNEEV 2907 Query: 3753 -------DYKYKELLRKEGTSKEFRLAVLDIKLEEKVRTAVTHVASSSGITINSFFQAVW 3805 DYK + + F +++K+ + + +A+ + +T+ A + Sbjct: 2908 PVLNMPTDYKRPK-------RRSFAGDRINLKINSETYNQLNKLATENEVTMYMLMLAGY 2960 Query: 3806 GILLSKYDNAEDVVFGAVISGRSPEIEGIERMVGLFINTIPVRVRLSG-KTFHELAGEIQ 3864 LLSKY ED+V G+ I+GR + ++G+F+NT+ +R G ++F E E++ Sbjct: 2961 TTLLSKYSGQEDIVVGSPIAGRKHV--DLNNVMGMFVNTLAMRNYPKGNRSFREYLKEVK 3018 Query: 3865 SSFISS---EQYGYVPLSDI----QAWSHRDLINHVMVFENYPLDREIRDTDG---QQME 3914 + + + + Y + L + + S L + ++VF++ D + + DG +E Sbjct: 3019 ENTLKAYENQDYQFEELVEKVNVRRDISRNPLFDTMLVFQH--TDNMLLNLDGLKVSMLE 3076 Query: 3915 YGFQIAGCEILEHTNYDFSIIIEPGEDFIIRIVYNALAYDKETISILESYLLAIIGQVTA 3974 +I +I H + E + I Y Y KETI + + ++ +V Sbjct: 3077 DQREIVKFDITIHVS-------ELEHGLGLEIEYCTALYKKETIERFLEHFINVLREVVE 3129 Query: 3975 CPQIEAGDVEVLSQEEKLKLMNVFNKPNRREAAD 4008 P+ + ++++L+++EK KL+N FN + A + Sbjct: 3130 NPEQKLSEIDILTEKEKSKLLNEFNNTKGKYAKE 3163 Score = 102 bits (253), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 71/302 (23%), Positives = 138/302 (45%), Gaps = 12/302 (3%) Query: 1340 QISLVIHS-NDTHGVVHHETVGLYLRGELNKAALETAYHKVLNRHESLRSTISADGNEQ- 1397 Q ++ H+ D + ++ E + + ++G ++ LE +++ ++ RHE LR+ + E+ Sbjct: 4231 QKGMLFHALEDKNSSMYFEQIVMDIKGTVDVDILEKSFNTIMRRHEILRAAFEYELVEEP 4290 Query: 1398 --IVASHANADIFFADILADYSALGDEAINQALLKENAAAFDSVMGPLIRLRVLATARHE 1455 ++ + DI + + I L + F+ L+R+ ++ + Sbjct: 4291 RHVILQDRKVGFKYYDIQDESIEQKTKFIENYLQNDKQKGFNLSEDTLMRISLIQMNQDS 4350 Query: 1456 YLLALSAHHIIADGWSLIVFLQELAALYSTECTGTRSLLPTPTPFSDYAIWQKRMLESQP 1515 Y L S HHI+ DGW L + L E +Y + G S L PTP+SDY W LE Q Sbjct: 4351 YKLVWSHHHILLDGWCLGIILGEFFDVYGRKMKGEDSHLAEPTPYSDYIRW----LEEQD 4406 Query: 1516 KEKAAAYWKNKFSVQTPAFELPSFRIRDAAGVRKGSRHRYVLDIPLTAKLKAVSQSMKVS 1575 KE+ A+WK+ ++P +I + K + + ++ +V+ Sbjct: 4407 KEEGLAHWKSYLDGYEEQAQVP--KILNKVNEYKRKEKMIEFSKEMNRNIIQLANRNQVT 4464 Query: 1576 LFTVLLSAYKVLLYRISNHKELVVGIPTAGQMQM--GQKHLVGYCLNILPFSTTINPEMT 1633 TVL + + +LL R +N +++V G +G+ G + +VG +N +P + + + Sbjct: 4465 FNTVLQAIWGILLARYNNIEDVVFGTVVSGREAKVEGIEAMVGLFINTIPTRVKLEKDSS 4524 Query: 1634 FR 1635 F+ Sbjct: 4525 FK 4526 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 23,705,278,313 Number of extensions: 1034770907 Number of successful extensions: 2678053 Number of sequences better than 1.0e-05: 27687 Number of HSP's gapped: 2522248 Number of HSP's successfully gapped: 46737 Length of query: 4011 Length of database: 3,060,696,203 Length adjustment: 156 Effective length of query: 3855 Effective length of database: 1,591,017,863 Effective search space: 6133373861865 Effective search space used: 6133373861865 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 142 (59.3 bits)