BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0560.0024.p (865 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B9E3Q3.1 B9E3Q3_CLOK1 Putative uncharacterized protein 595 e-168 A5MZS3.1 A5MZS3_CLOK5 Predicted NRPS adenylation domain 595 e-168 Q93I56.1 Q93I56_BACSU Iturin A synthetase A 579 e-163 B8I5D1.1 B8I5D1_CLOCE Amino acid adenylation domain protein 578 e-163 B3TLA1.1 B3TLA1_BACSU Iturin A synthetase A 577 e-162 >B9E3Q3.1 B9E3Q3_CLOK1 Putative uncharacterized protein Length = 841 Score = 595 bits (1535), Expect = e-168, Method: Compositional matrix adjust. Identities = 318/857 (37%), Positives = 507/857 (59%), Gaps = 38/857 (4%) Query: 2 LIARSKDAHKGITFINGDNEHNYYSYKEMYTRATGALRFLRSKGIQSGDEVIFQIENNET 61 +I +K + GITF++G N+ + +Y E++ A L L+ GI+ G E++FQIE++E Sbjct: 9 VIESAKKSPNGITFVSGKNKEKHLNYDELFLEACKILGVLQLDGIKPGFELVFQIEDDEK 68 Query: 62 FILAFWACILGGMIPVPVNVGNNDEHKHKLIKIWNVLHRPFLITDSRSLLKPD---LTAH 118 FI FWACILG +IPVP+ V N DE++ KL+K+W +L+ PFLITD + L + H Sbjct: 69 FISVFWACILGKIIPVPITVANKDEYRLKLLKVWKILNNPFLITDKKIFLSIEKYLFKNH 128 Query: 119 QTDFYRFASSITNRTIHTETL---EYSGTEDVVLCSPESHDIAFIQFSSGTTGDPKGVTL 175 T+ Y +I + TI E + E SG L DIAFIQFSSG+TGDPKGV L Sbjct: 129 STEEYE---AIKHNTIFLEEIKENERSGQ----LMQSSLDDIAFIQFSSGSTGDPKGVVL 181 Query: 176 THDNLLTNLYDLKKSRNYSANDSFLSWMPLTHDMGMIVFHLLPLTCGGSQSLLPTWVFIR 235 TH NLLTN+ + + D LSWMPLTHDMG+I FHL +Q ++PT +FIR Sbjct: 182 THKNLLTNINAIINCAKLTDGDRALSWMPLTHDMGLIGFHLTTTMLKINQYIIPTTLFIR 241 Query: 236 RPTLWIKKASDLKSTVIASPNFGMKYFLTFFYRSQCSYEWDLSNVRVLLDAAEPIDAKLC 295 RP LW+ K + + ++ +SPNFG KYFL+ F + + + EWDLS +R++ + AEPI LC Sbjct: 242 RPNLWMHKVNQHRISLTSSPNFGYKYFLSHF-KPESAEEWDLSCIRLIFNGAEPISIDLC 300 Query: 296 NEFLEVMDKFSLPRTSLLPGYGLAEATAAVTLYKPGHEFTSYNIVRSSINTGSRVQIVEE 355 EFL M+ + L + S+ YGLAEA+ AVT E S +++R S++ G +V + Sbjct: 301 EEFLNKMECYKLNKKSIFNVYGLAEASLAVTFPSVNEEMASVHVLRGSLSVGDKVIEGKG 360 Query: 356 NYKDKEYIVSLVDLGNPIENCFVRVCDEEDRVLDECVVGHVQIKGNNVTNGYYNNEEATR 415 N + L DLG+P+ +C VR+C++ + +L + +G++QI+G+NVT YYNNEEAT Sbjct: 361 NGS-----IRLADLGSPVTDCSVRICNDNNEILPDKTLGNIQIRGDNVTERYYNNEEATS 415 Query: 416 KVFTKDGWLRTGDLGFMKDGSLIVTGREKDIIFINGQNFYPQDIERVAEEFTGTRIGVTA 475 K+ KDGWL TGDLGF+++ LIVTGR KDIIF+NGQN+YP DIE+ +E G +G A Sbjct: 416 KLILKDGWLDTGDLGFIENNRLIVTGRAKDIIFVNGQNYYPHDIEKASEGVEGIELGKIA 475 Query: 476 ACGVYNEQLATEEVILFVNYKDKPETFVPLAIELRKQLNLKVGIHVRHIIPVKKILKTTS 535 CGV++ + + ++ F+ +K K E F+PLA+EL++ ++ G+++ IIPVK I KTTS Sbjct: 476 LCGVFDNRFQRDVILAFIMFKKKIEEFMPLALELKRYISYNRGVNLDFIIPVKHIPKTTS 535 Query: 536 GKVQRYKMKNLFLEGQFTGLLAEMEEVTNTITSRIDADQPKDTVEAALLSIWANVLGNDR 595 GK+QRYK+ ++L+G++ +L EME + + + P +E L+S+ L Sbjct: 536 GKIQRYKLGEMYLQGEYNDVLKEMEYLKERLCKDKIYENPITEIEKTLVSVCGEFLPVSS 595 Query: 596 LGVKDNFFEIGGTSTLLAQMFEQVDREYPGKITLTDLFGHPSISKLAGLIRQDGSDINAS 655 + + DNFF+IG +S +L Q+ +++ YP KI++ DLF +P+I+KLA + + + Sbjct: 596 ININDNFFDIGASSIILNQITHRLESIYPEKISVMDLFAYPTIAKLAAFLEK-----GQA 650 Query: 656 AHIRALELPEEFFKNGSHAEEEDGLSRTLSFSVDHKFTGQLKRIAAA---EHLKHESILL 712 + L++PEEF + D +S + F + Q K + +++ E + Sbjct: 651 ITLPILKIPEEFIN-----KRRDIISAPVMFQF-KLYQEQYKSVQGLCRNKNISVEDFMT 704 Query: 713 SMFVYLLYELSPSARIEVQTMMDGSGWVVPFTADFAQIDRLEDLFTLANETVKPGTREIY 772 S+++++L +S + +Q M+ V ++ + I ++++ L+ + + G Y Sbjct: 705 SLYIFMLSRVSKEPVVSIQLMIHKEDMV--YSGSY-NISKMKEFSHLSPDKISEGGF-WY 760 Query: 773 HVQDVSKFFIHKKNSVVPFICKEHLNLSAG-NLLDVYDLVLKFKEDHNGIHFVCEFNSNE 831 + DV + + + S + +S LL+VYD++++ + I F CE+N+ + Sbjct: 761 SINDVDQVRLERDKSSYAILLYNREFMSCNVELLNVYDILMEMNTKDDEIEFFCEYNNLK 820 Query: 832 IRSEPVLNFIQRYAQAL 848 + + + + YA ++ Sbjct: 821 LSAHGISKMMNDYANSI 837 >A5MZS3.1 A5MZS3_CLOK5 Predicted NRPS adenylation domain Length = 841 Score = 595 bits (1535), Expect = e-168, Method: Compositional matrix adjust. Identities = 318/857 (37%), Positives = 507/857 (59%), Gaps = 38/857 (4%) Query: 2 LIARSKDAHKGITFINGDNEHNYYSYKEMYTRATGALRFLRSKGIQSGDEVIFQIENNET 61 +I +K + GITF++G N+ + +Y E++ A L L+ GI+ G E++FQIE++E Sbjct: 9 VIESAKKSPNGITFVSGKNKEKHLNYDELFLEACKILGVLQLDGIKPGFELVFQIEDDEK 68 Query: 62 FILAFWACILGGMIPVPVNVGNNDEHKHKLIKIWNVLHRPFLITDSRSLLKPD---LTAH 118 FI FWACILG +IPVP+ V N DE++ KL+K+W +L+ PFLITD + L + H Sbjct: 69 FISVFWACILGKIIPVPITVANKDEYRLKLLKVWKILNNPFLITDKKIFLSIEKYLFKNH 128 Query: 119 QTDFYRFASSITNRTIHTETL---EYSGTEDVVLCSPESHDIAFIQFSSGTTGDPKGVTL 175 T+ Y +I + TI E + E SG L DIAFIQFSSG+TGDPKGV L Sbjct: 129 STEEYE---AIKHNTIFLEEIKENERSGQ----LMQSSLDDIAFIQFSSGSTGDPKGVVL 181 Query: 176 THDNLLTNLYDLKKSRNYSANDSFLSWMPLTHDMGMIVFHLLPLTCGGSQSLLPTWVFIR 235 TH NLLTN+ + + D LSWMPLTHDMG+I FHL +Q ++PT +FIR Sbjct: 182 THKNLLTNINAIINCAKLTDGDRALSWMPLTHDMGLIGFHLTTTMLKINQYIIPTTLFIR 241 Query: 236 RPTLWIKKASDLKSTVIASPNFGMKYFLTFFYRSQCSYEWDLSNVRVLLDAAEPIDAKLC 295 RP LW+ K + + ++ +SPNFG KYFL+ F + + + EWDLS +R++ + AEPI LC Sbjct: 242 RPNLWMHKVNQHRISLTSSPNFGYKYFLSHF-KPESAEEWDLSCIRLIFNGAEPISIDLC 300 Query: 296 NEFLEVMDKFSLPRTSLLPGYGLAEATAAVTLYKPGHEFTSYNIVRSSINTGSRVQIVEE 355 EFL M+ + L + S+ YGLAEA+ AVT E S +++R S++ G +V + Sbjct: 301 EEFLNKMECYKLNKKSIFNVYGLAEASLAVTFPSVNEEMASVHVLRGSLSVGDKVIEGKG 360 Query: 356 NYKDKEYIVSLVDLGNPIENCFVRVCDEEDRVLDECVVGHVQIKGNNVTNGYYNNEEATR 415 N + L DLG+P+ +C VR+C++ + +L + +G++QI+G+NVT YYNNEEAT Sbjct: 361 NGS-----IRLADLGSPVTDCSVRICNDNNEILPDKTLGNIQIRGDNVTERYYNNEEATS 415 Query: 416 KVFTKDGWLRTGDLGFMKDGSLIVTGREKDIIFINGQNFYPQDIERVAEEFTGTRIGVTA 475 K+ KDGWL TGDLGF+++ LIVTGR KDIIF+NGQN+YP DIE+ +E G +G A Sbjct: 416 KLILKDGWLDTGDLGFIENNRLIVTGRAKDIIFVNGQNYYPHDIEKASEGVEGIELGKIA 475 Query: 476 ACGVYNEQLATEEVILFVNYKDKPETFVPLAIELRKQLNLKVGIHVRHIIPVKKILKTTS 535 CGV++ + + ++ F+ +K K E F+PLA+EL++ ++ G+++ IIPVK I KTTS Sbjct: 476 LCGVFDNRFQRDVILAFIMFKKKIEEFMPLALELKRYISYNRGVNLDFIIPVKHIPKTTS 535 Query: 536 GKVQRYKMKNLFLEGQFTGLLAEMEEVTNTITSRIDADQPKDTVEAALLSIWANVLGNDR 595 GK+QRYK+ ++L+G++ +L EME + + + P +E L+S+ L Sbjct: 536 GKIQRYKLGEMYLQGEYNDVLKEMEYLKERLCKDKIYENPITEIEKTLVSVCGEFLPVSS 595 Query: 596 LGVKDNFFEIGGTSTLLAQMFEQVDREYPGKITLTDLFGHPSISKLAGLIRQDGSDINAS 655 + + DNFF+IG +S +L Q+ +++ YP KI++ DLF +P+I+KLA + + + Sbjct: 596 ININDNFFDIGASSIILNQITHRLESIYPEKISVMDLFAYPTIAKLAAFLEK-----GQA 650 Query: 656 AHIRALELPEEFFKNGSHAEEEDGLSRTLSFSVDHKFTGQLKRIAAA---EHLKHESILL 712 + L++PEEF + D +S + F + Q K + +++ E + Sbjct: 651 ITLPILKIPEEFIN-----KRRDIISAPVMFQF-KLYQEQYKSVQGLCRNKNISVEDFMT 704 Query: 713 SMFVYLLYELSPSARIEVQTMMDGSGWVVPFTADFAQIDRLEDLFTLANETVKPGTREIY 772 S+++++L +S + +Q M+ V ++ + I ++++ L+ + + G Y Sbjct: 705 SLYIFMLSRVSKEPVVSIQLMIHKEDMV--YSGSY-NISKMKEFSHLSPDKISEGGF-WY 760 Query: 773 HVQDVSKFFIHKKNSVVPFICKEHLNLSAG-NLLDVYDLVLKFKEDHNGIHFVCEFNSNE 831 + DV + + + S + +S LL+VYD++++ + I F CE+N+ + Sbjct: 761 SINDVDQVRLERDKSSYAILLYNREFMSCNVELLNVYDILMEMNTKDDEIEFFCEYNNLK 820 Query: 832 IRSEPVLNFIQRYAQAL 848 + + + + YA ++ Sbjct: 821 LSAHGISKMMNDYANSI 837 >Q93I56.1 Q93I56_BACSU Iturin A synthetase A Length = 3982 Score = 579 bits (1492), Expect = e-163, Method: Compositional matrix adjust. Identities = 279/655 (42%), Positives = 427/655 (65%), Gaps = 14/655 (2%) Query: 5 RSKDAHKGITFINGDNEHNYYSYKEMYTRATGALRFLRSKGIQSGDEVIFQIENNETFIL 64 RS + +GI FI D SY++++ A G L +L+ GI+ E++FQI+ N++F++ Sbjct: 16 RSSISDRGIRFIESDKNETVVSYRQLFEEAQGYLGYLQHLGIKPKQEIVFQIQENKSFVV 75 Query: 65 AFWACILGGMIPVPVNVGNNDEHKHKLIKIWNVLHRPFLITDSRSLLKPDLTAHQTDFYR 124 AFWACILGGMIPVPV++G +D+HK K+ +IWN+L+ PFLI + L K A + D Sbjct: 76 AFWACILGGMIPVPVSIGEDDDHKLKVWRIWNILNHPFLIASEKVLDKIKKYAAEHDLQD 135 Query: 125 FASSITNRT--IHTETLEYSGTEDVVLCSPESHDIAFIQFSSGTTGDPKGVTLTHDNLLT 182 F + ++ I +T +Y + P++ ++AFIQFSSG+TGDPKGV LTH NL+ Sbjct: 136 FHHQLNEKSDIIQDQTYDYPAS----FYEPDADELAFIQFSSGSTGDPKGVMLTHHNLIH 191 Query: 183 NLYDLKKSRNYSANDSFLSWMPLTHDMGMIVFHLLPLTCGGSQSLLPTWVFIRRPTLWIK 242 N + + + DSFLSWMPLTHDMG+I HL+P G +Q+L+PT +FIRRP LW+K Sbjct: 192 NTCAIGTALAIHSKDSFLSWMPLTHDMGLIACHLVPFITGINQNLMPTELFIRRPILWMK 251 Query: 243 KASDLKSTVIASPNFGMKYFLTFFYRSQCSYEWDLSNVRVLLDAAEPIDAKLCNEFLEVM 302 KA + K+++++SPNFG YFL F + +WDLS+++V+ + AEPI +LC+EFL+ Sbjct: 252 KAHEHKASILSSPNFGYNYFLKFL---KNEPDWDLSHIKVIANGAEPILPELCDEFLKRC 308 Query: 303 DKFSLPRTSLLPGYGLAEATAAVTLYKPGHEFTSYNIVRSSINTGSRVQIVEENYKDKEY 362 F+L R+++L YGLAEA+ K G EF + R +N G R V K+ + Sbjct: 309 AAFNLKRSAILNVYGLAEASVGAAFSKIGKEFVPVYLHRDYLNLGERAVNVS---KEDQN 365 Query: 363 IVSLVDLGNPIENCFVRVCDEEDRVLDECVVGHVQIKGNNVTNGYYNNEEATRKVFTKDG 422 S V++G PI+ C +R+ DE + +++ ++GH+QIKG+NVT GYYNN E+T KV T DG Sbjct: 366 CASFVEVGQPIDYCQLRISDETNERVEDGIIGHIQIKGDNVTQGYYNNPESTEKVLTSDG 425 Query: 423 WLRTGDLGFMKD-GSLIVTGREKDIIFINGQNFYPQDIERVAEEFTGTRIGVTAACGVYN 481 W++TGDLGF+ + G+L+VTGREKDIIF+NG+N YP DIERVA E +G AACGVY+ Sbjct: 426 WVKTGDLGFISESGNLVVTGREKDIIFVNGKNIYPHDIERVAIEMEEVDLGRVAACGVYD 485 Query: 482 EQLATEEVILFVNYKDKPETFVPLAIELRKQLNLKVGIHVRHIIPVKKILKTTSGKVQRY 541 ++ + E++LFV YK PE F PL E++K L + G ++ ++P++K+ KTTSGKV+RY Sbjct: 486 QKTQSGEIVLFVVYKKSPEKFAPLVKEIKKHLYKRGGWSIKEVLPIRKLPKTTSGKVKRY 545 Query: 542 KMKNLFLEGQFTGLLAEMEEVTNTITSRIDADQPKDTVEAALLSIWANVLGNDRLGVKDN 601 ++ + G F+ A + E + + P +E LLSI++ VL ++ + D+ Sbjct: 546 ELARQYEAGNFSTESAAINECLES-SPETSGQTPIHEIETELLSIFSEVLNGKKVHLADS 604 Query: 602 FFEIGGTSTLLAQMFEQVDREYPGKITLTDLFGHPSISKLAGLIRQDGSDINASA 656 +F++G S L+Q+ E++++++ ++ ++DLF +PSI+ LA + + ++I A Sbjct: 605 YFDMGANSLQLSQIAERIEQKFGRELAVSDLFTYPSITDLAAYLSESRAEIKQDA 659 Score = 114 bits (286), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 172/756 (22%), Positives = 298/756 (39%), Gaps = 130/756 (17%) Query: 1 MLIARSKDAHKGITFINGDNEHNYYSYKEMYTRATGALRFLRSKGIQSGDEVIFQIENNE 60 M +S D H+ + F N Y+Y+++ RA R LR+KG+Q+ V + Sbjct: 2959 MQAEQSPD-HEAVIFGN-----ERYTYRQLNERANRLARTLRTKGVQADQFVAIICPHRI 3012 Query: 61 TFILAFWACILGGMIPVPVNVGNNDEHKHKLIKIWNVLHRPFLITDSRSLLKPDLTAHQT 120 I+ A + G VP++ E+ I+ R ++ RSLL D + Sbjct: 3013 ELIVGILAVLKAGGAYVPID----PEYPENRIQYMLRDSRAEVVLTQRSLL--DQLPYDG 3066 Query: 121 DFYRFASSITNRTIHTETLEYSGTEDVVLCSPESHDIAFIQFSSGTTGDPKGVTLTHDNL 180 D + H E + D +HD+A++ ++SG+TG+PKGV + H L Sbjct: 3067 DVVLLDEE---NSYHEEHSNFESDSD-------AHDLAYMIYTSGSTGNPKGVLIEHQGL 3116 Query: 181 LTNLYDLKKSRNYSANDSFLSWMPLTHDMGMIVFHLLPLTCG-------GSQSLLPTWVF 233 ++ K+ +F + ++ D+ + PL G G Sbjct: 3117 ADYIWWAKEVYVRGEKTNFPLYSSISFDLTVTSI-FTPLVTGNTIIVFDGEDKSAVLSEI 3175 Query: 234 IRRPTLWIKKASDLKSTVIASPNFGMKYFLTFFYRSQCSYEWDLSNVRVLLDAAEPIDAK 293 +R + + K + VI N + +R ++ E + + Sbjct: 3176 MRDSRIDMIKLTPAHLHVIKEMNIAGD-----------------TAIRKMIVGGENLSTR 3218 Query: 294 LCNEFLEVMDKFSLPRTSLLPGYGLAEATAAVTLYKPGHEFTSYNIVRSSINTGSRVQIV 353 L V ++F R + YG EA +Y ++ VR Sbjct: 3219 LAKS---VSEQFK-GRLDIFNEYGPTEAVVGCMIYH-------FDAVR------------ 3255 Query: 354 EENYKDKEYIVSLVDLGNPIENCFVRVCDEEDRVLDECVVGHVQIKGNNVTNGYYNNEEA 413 DK V +G P N + V D ++ V+G + I G V GY+N + Sbjct: 3256 -----DKR---EFVPIGTPAANTDIYVADASRNLVPIGVIGEIYISGPGVARGYWNRPDL 3307 Query: 414 TRKVFTKDGWL------RTGDLG-FMKDGSLIVTGREKDIIFINGQNFYPQDIERVAEEF 466 T + F ++ ++ ++GDL +KDG+L+ GR + + I G +IE Sbjct: 3308 TEEKFVENPYVPGAKMYKSGDLAKRLKDGNLVYIGRVDEQVKIRGHRIELGEIEAAMHNA 3367 Query: 467 TGTRIGVTAACGVYNEQLATEEVILFVNYKDKPETFVPLAIELRKQLNLKVGIHV--RHI 524 + AA V E+ +++ + DKP A +LR+QL+ + ++ + Sbjct: 3368 EAVQ---KAAVTVKEEEDGLKQLCAYY-VSDKPIA----AAQLREQLSSGLPDYMVPSYF 3419 Query: 525 IPVKKILKTTSGKVQRYKMKNLFLEGQFTGLLAEMEEVTNTITSRIDADQPKDTVEAALL 584 + ++ + T++GK+ R L + L E V P + E+ L Sbjct: 3420 VRLEHMPLTSNGKINRKA-----LPAPESSLQQTAEYVP-----------PGNETESKLT 3463 Query: 585 SIWANVLGNDRLGVKDNFFEIGGTSTLLAQMFEQVDREYPGKITLTDLFGHPSISKLAGL 644 +W VLG G+K NFF++GG S A + ++ +E ++L D+F P+I +LA Sbjct: 3464 DLWKEVLGISHAGIKHNFFDLGGNSIRAAALAARIHKELDVNLSLKDIFKFPTIEQLAD- 3522 Query: 645 IRQDGSDINASAHIRAL-ELPEEFFKNGSHAEEEDGLSRTLSFSVDHKFTGQLK------ 697 + D N I A E+P ++ S LS T + + TG +K Sbjct: 3523 -KALHMDKNRYVPIPAAKEMP--YYPVSSAQRRMYLLSHTEGGELTYNMTGAMKVEGTID 3579 Query: 698 --RIAAAEH---LKHESILLSMFVYLLYELSPSARI 728 R+ AA +HE++ S + LYE P+ RI Sbjct: 3580 PERLNAAFRKLIARHEALRTS---FDLYEGEPAQRI 3612 >B8I5D1.1 B8I5D1_CLOCE Amino acid adenylation domain protein Length = 3235 Score = 578 bits (1490), Expect = e-163, Method: Compositional matrix adjust. Identities = 292/647 (45%), Positives = 419/647 (64%), Gaps = 5/647 (0%) Query: 1 MLIARSKDAHKGITFINGDNEHNYYSYKEMYTRATGALRFLRSKGIQSGDEVIFQIENNE 60 +++AR + KGITFI + E ++ Y E+Y A L L++ G + GDEVIFQI+NN Sbjct: 10 LIVARQYEKSKGITFIISETEEHFVPYGELYHGARALLYNLQTAGFKKGDEVIFQIDNNR 69 Query: 61 TFILAFWACILGGMIPVPVNVGNNDEHKHKLIKIWNVLHRPFLITDSRSLLKPDLTAHQT 120 F+ AFWACILGGMIPVPV G NDEHK KL KIW++L P ++ + + Sbjct: 70 QFMFAFWACILGGMIPVPVTTGTNDEHKLKLFKIWDILKNPKMLASDDFFERLKSFGNNN 129 Query: 121 DFYRFASSITNRTIHTETLEYSGTEDVVLCSPESHDIAFIQFSSGTTGDPKGVTLTHDNL 180 D R + RT+ E LE + + E +DIAFIQFSSG+TGDPKGV +TH N+ Sbjct: 130 DLSRQVDIMQTRTLSLENLEKTDFFGEIE-KAEENDIAFIQFSSGSTGDPKGVIITHKNV 188 Query: 181 LTNLYDLKKSRNYSANDSFLSWMPLTHDMGMIVFHLLPLTCGGSQSLLPTWVFIRRPTLW 240 L ++ + + N ++ DS L+WMPLTHDMG+I H+ + +Q + T +FIR P+LW Sbjct: 189 LYDIGSVIRWVNINSEDSGLNWMPLTHDMGLIGTHIKDVIACINQYNIETQLFIRHPSLW 248 Query: 241 IKKASDLKSTVIASPNFGMKYFLTFFYRSQCSYEWDLSNVRVLLDAAEPIDAKLCNEFLE 300 I+KAS+ K T++ SPNFG K+FLTFF + + +WDLS VR++ + AEPI +LC+EFLE Sbjct: 249 IQKASEHKVTLLYSPNFGYKHFLTFF-KPENKKDWDLSKVRLIYNGAEPISYELCDEFLE 307 Query: 301 VMDKFSLPRTSLLPGYGLAEATAAVTLYKPGHEFTSYNIVRSSINTGSRVQIVEENYKDK 360 + ++ L R S+ YGLAE T AVT + G E + R+ +N G V+ V KD Sbjct: 308 KLSQYGLKRNSMYTVYGLAEGTIAVTFPRLGDEMRFITLDRNYLNIGDTVREVS---KDD 364 Query: 361 EYIVSLVDLGNPIENCFVRVCDEEDRVLDECVVGHVQIKGNNVTNGYYNNEEATRKVFTK 420 S D G PI +C+VR+CD ++ + E +G++ I G NVT+GYYNN+EATRK TK Sbjct: 365 TRGCSFADEGYPIYDCYVRICDIDNNDIGENKIGYICISGANVTSGYYNNKEATRKAITK 424 Query: 421 DGWLRTGDLGFMKDGSLIVTGREKDIIFINGQNFYPQDIERVAEEFTGTRIGVTAACGVY 480 DGWL TGDLGFM+DG L++TGR KD+IF+ GQN+Y DIERVA+E G +G A G + Sbjct: 425 DGWLNTGDLGFMRDGRLVITGRAKDVIFVKGQNYYSHDIERVAQEVDGIDVGKIVAVGAF 484 Query: 481 NEQLATEEVILFVNYKDKPETFVPLAIELRKQLNLKVGIHVRHIIPVKKILKTTSGKVQR 540 NE++ ++E+ILFV +K K + F+ L L+K ++ ++GI V +IP+K I KTTSGKVQR Sbjct: 485 NEKIKSDELILFVLFKMKVDKFIGLVRSLKKLISERMGIEVSQVIPIKSIPKTTSGKVQR 544 Query: 541 YKMKNLFLEGQFTGLLAEMEEVTNTITSRIDADQPKDTVEAALLSIWANVLGNDRLGVKD 600 YK++ +++GQ+ + ++E + + DQP++ ++A L+ IW VLG R+G+KD Sbjct: 545 YKLRESYIKGQYDTIKNDIELLLKSEAECRLIDQPENEIQAKLVEIWQEVLGLKRIGIKD 604 Query: 601 NFFEIGGTSTLLAQMFEQVDREYPGKITLTDLFGHPSISKLAGLIRQ 647 NFFE+GG S L Q+ ++ E+ ++ T LF P +S+LA +I + Sbjct: 605 NFFELGGDSLKLTQIISRIREEFEVELEQTLLFETPVLSELAEIIEK 651 Score = 57.8 bits (138), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 25/68 (36%), Positives = 41/68 (60%) Query: 575 PKDTVEAALLSIWANVLGNDRLGVKDNFFEIGGTSTLLAQMFEQVDREYPGKITLTDLFG 634 PK E L+ +W N+LG + LG+ D FF +GG S LL Q+ ++ +P + + DL+ Sbjct: 3124 PKSETEKKLVPMWQNLLGIEGLGIHDEFFALGGDSLLLVQLHSKIKEVFPTDLAVVDLYK 3183 Query: 635 HPSISKLA 642 + +I+ LA Sbjct: 3184 YNTIALLA 3191 >B3TLA1.1 B3TLA1_BACSU Iturin A synthetase A Length = 3982 Score = 577 bits (1487), Expect = e-162, Method: Compositional matrix adjust. Identities = 278/655 (42%), Positives = 426/655 (65%), Gaps = 14/655 (2%) Query: 5 RSKDAHKGITFINGDNEHNYYSYKEMYTRATGALRFLRSKGIQSGDEVIFQIENNETFIL 64 RS + +GI FI D SY++++ A G L +L+ GI+ E++FQI+ N++F++ Sbjct: 16 RSSISDRGIRFIESDKNETVVSYRQLFEEAQGYLGYLQHLGIKPKQEIVFQIQENKSFVV 75 Query: 65 AFWACILGGMIPVPVNVGNNDEHKHKLIKIWNVLHRPFLITDSRSLLKPDLTAHQTDFYR 124 AFWACILGGMIPVPV++G +D+HK K+ +IWN+L+ PFLI + L K A + D Sbjct: 76 AFWACILGGMIPVPVSIGEDDDHKLKVWRIWNILNHPFLIASEKVLDKIKKYAAEHDLQD 135 Query: 125 FASSITNRT--IHTETLEYSGTEDVVLCSPESHDIAFIQFSSGTTGDPKGVTLTHDNLLT 182 F + ++ I +T +Y + P++ ++AFIQFSSG+TGDPKGV LTH NL+ Sbjct: 136 FHHQLNEKSDIIQDQTYDYPAS----FYEPDADELAFIQFSSGSTGDPKGVMLTHHNLIH 191 Query: 183 NLYDLKKSRNYSANDSFLSWMPLTHDMGMIVFHLLPLTCGGSQSLLPTWVFIRRPTLWIK 242 N + + + DSFLSWMPLTHDMG+I HL+P G +Q+L+PT +FIRRP LW+K Sbjct: 192 NTCAIGTALAIHSKDSFLSWMPLTHDMGLIACHLVPFITGINQNLMPTELFIRRPILWMK 251 Query: 243 KASDLKSTVIASPNFGMKYFLTFFYRSQCSYEWDLSNVRVLLDAAEPIDAKLCNEFLEVM 302 KA + K+++++SPNFG YFL F + +WDLS+++V+ + AEPI +LC+EFL+ Sbjct: 252 KAHEHKASILSSPNFGYNYFLKFL---KNEPDWDLSHIKVIANGAEPILPELCDEFLKRC 308 Query: 303 DKFSLPRTSLLPGYGLAEATAAVTLYKPGHEFTSYNIVRSSINTGSRVQIVEENYKDKEY 362 F+L R+++L YGLAEA+ K G EF + R +N G R V K+ + Sbjct: 309 AAFNLKRSAILNVYGLAEASVGAAFSKIGKEFVPVYLHRDYLNLGERAVKVS---KEDQN 365 Query: 363 IVSLVDLGNPIENCFVRVCDEEDRVLDECVVGHVQIKGNNVTNGYYNNEEATRKVFTKDG 422 S V++G PI+ C +R+ DE + +++ ++GH+QIKG+NVT GYYNN E+T K T DG Sbjct: 366 CASFVEVGQPIDYCQLRISDETNERVEDGIIGHIQIKGDNVTQGYYNNPESTEKALTSDG 425 Query: 423 WLRTGDLGFMKD-GSLIVTGREKDIIFINGQNFYPQDIERVAEEFTGTRIGVTAACGVYN 481 W++TGDLGF+ + G+L+VTGREKDIIF+NG+N YP DIERVA E +G AACGVY+ Sbjct: 426 WVKTGDLGFISESGNLVVTGREKDIIFVNGKNVYPHDIERVAIEMEEVDLGRVAACGVYD 485 Query: 482 EQLATEEVILFVNYKDKPETFVPLAIELRKQLNLKVGIHVRHIIPVKKILKTTSGKVQRY 541 ++ + E++LFV YK PE F PL E++K L + G ++ ++P++K+ KTTSGKV+RY Sbjct: 486 QKTQSGEIVLFVVYKKSPEKFAPLVKEIKKHLYKRGGWSIKEVLPIRKLPKTTSGKVKRY 545 Query: 542 KMKNLFLEGQFTGLLAEMEEVTNTITSRIDADQPKDTVEAALLSIWANVLGNDRLGVKDN 601 ++ + G F+ A + E + + P +E LLSI++ VL ++ + D+ Sbjct: 546 ELARQYEAGNFSTESAAINECLES-SPETSGQTPIHEIETELLSIFSEVLDGKKVHLADS 604 Query: 602 FFEIGGTSTLLAQMFEQVDREYPGKITLTDLFGHPSISKLAGLIRQDGSDINASA 656 +F++G S L+Q+ E++++++ ++ ++DLF +PSI+ LA + + ++I A Sbjct: 605 YFDMGANSLQLSQIAERIEQKFGRELAVSDLFTYPSITDLAAYLSESRAEIKQDA 659 Score = 110 bits (276), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 166/756 (21%), Positives = 297/756 (39%), Gaps = 130/756 (17%) Query: 1 MLIARSKDAHKGITFINGDNEHNYYSYKEMYTRATGALRFLRSKGIQSGDEVIFQIENNE 60 M +S D H+ + F N Y+Y+++ RA R LR+KG+Q+ V + Sbjct: 2959 MQAEQSPD-HEAVIFGN-----ERYTYRQLNERANRLARTLRTKGVQADQFVAIISPHRI 3012 Query: 61 TFILAFWACILGGMIPVPVNVGNNDEHKHKLIKIWNVLHRPFLITDSRSLLKPDLTAHQT 120 I+ A + G VP++ E+ I+ R ++ RSLL D + Sbjct: 3013 ELIVGILAVLKAGGAYVPID----PEYPEDRIQYMLRDSRAEVVLTQRSLL--DQLPYDG 3066 Query: 121 DFYRFASSITNRTIHTETLEYSGTEDVVLCSPESHDIAFIQFSSGTTGDPKGVTLTHDNL 180 D + E Y + ++HD+A++ ++SG+TG+PKGV + H L Sbjct: 3067 DI----------VLLDEENSYHEEHSNLESDSDAHDLAYMIYTSGSTGNPKGVLIEHQGL 3116 Query: 181 LTNLYDLKKSRNYSANDSFLSWMPLTHDMGMIVFHLLPLTCG-------GSQSLLPTWVF 233 ++ K+ +F + ++ D+ + PL G G Sbjct: 3117 ADYIWWAKEVYVRGEKTNFPLYSSISFDLTVTSI-FTPLVTGNTIIVFDGEDKSAVLSEI 3175 Query: 234 IRRPTLWIKKASDLKSTVIASPNFGMKYFLTFFYRSQCSYEWDLSNVRVLLDAAEPIDAK 293 +R + + K + VI N + +R ++ E + + Sbjct: 3176 MRDSRIDMIKLTPAHLHVIKEMNIAGG-----------------TAIRKMIVGGENLSTR 3218 Query: 294 LCNEFLEVMDKFSLPRTSLLPGYGLAEATAAVTLYKPGHEFTSYNIVRSSINTGSRVQIV 353 L V ++F R + YG EA +Y E Sbjct: 3219 LAKS---VSEQFK-GRLDIFNEYGPTEAVVGCMIYHFDAE-------------------- 3254 Query: 354 EENYKDKEYIVSLVDLGNPIENCFVRVCDEEDRVLDECVVGHVQIKGNNVTNGYYNNEEA 413 +DK V +G P N + V D ++ V+G + I G V GY+N + Sbjct: 3255 ----RDKR---EFVPIGTPAANTDIYVADASRNLVPIGVIGEIYISGPGVARGYWNRPDL 3307 Query: 414 TRKVFTKDGWL------RTGDLG-FMKDGSLIVTGREKDIIFINGQNFYPQDIERVAEEF 466 T + F ++ ++ ++GDL +KDG+L+ GR + + I G +IE Sbjct: 3308 TEEKFVENPYVPGAKMYKSGDLAKRLKDGNLVYIGRVDEQVKIRGHRIELGEIEAAMHNA 3367 Query: 467 TGTRIGVTAACGVYNEQLATEEVILFVNYKDKPETFVPLAIELRKQLNLKVGIHV--RHI 524 + AA V E+ +++ + DKP A +LR+ L+ ++ ++ + Sbjct: 3368 EAVQ---KAAVTVKEEEDGLKQLCAYY-VSDKPIA----AAQLREHLSSQLPDYMVPSYF 3419 Query: 525 IPVKKILKTTSGKVQRYKMKNLFLEGQFTGLLAEMEEVTNTITSRIDADQPKDTVEAALL 584 + ++ + T++GK+ R + A +++ + P + E+ L Sbjct: 3420 VRLEHMPLTSNGKINRKAL---------PAPEASLQQTAEYVP-------PGNETESKLT 3463 Query: 585 SIWANVLGNDRLGVKDNFFEIGGTSTLLAQMFEQVDREYPGKITLTDLFGHPSISKLAGL 644 +W VLG G+K NFF++GG S A + ++ +E ++L D+F P+I +LA Sbjct: 3464 DLWKEVLGISHAGIKHNFFDLGGNSIRAAALAARIHKELDVNLSLKDIFKFPTIEQLAD- 3522 Query: 645 IRQDGSDINASAHIRAL-ELPEEFFKNGSHAEEEDGLSRTLSFSVDHKFTGQL------- 696 + D N I A E+P ++ S LS T + + TG + Sbjct: 3523 -KALHMDKNRYVPIPAAKEMP--YYPVSSAQRRMYLLSHTEGGELTYNMTGAMNVEGAID 3579 Query: 697 -KRIAAAEH---LKHESILLSMFVYLLYELSPSARI 728 +RI AA +HE++ S + LYE P+ RI Sbjct: 3580 PERINAAFRKLIARHEALRTS---FDLYEGEPAQRI 3612 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.137 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 5,295,645,227 Number of extensions: 230215851 Number of successful extensions: 608369 Number of sequences better than 1.0e-05: 9032 Number of HSP's gapped: 599079 Number of HSP's successfully gapped: 10642 Length of query: 865 Length of database: 3,060,696,203 Length adjustment: 145 Effective length of query: 720 Effective length of database: 1,694,649,028 Effective search space: 1220147300160 Effective search space used: 1220147300160 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 136 (57.0 bits)