BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0560.0011.p (470 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0ZJT4.1 C0ZJT4_BREBN Two-component sensor histidine kinase EC=2... 493 e-137 A4J7U4.1 A4J7U4_DESRM Sensor protein EC=2.7.13.3 392 e-107 B1KUF5.1 B1KUF5_CLOBM Sensor protein EC=2.7.13.3 319 5e-85 C3KZH3.1 C3KZH3_CLOB6 Sensor histidine kinase EC=2.7.3.- 318 6e-85 B1QQN7.1 B1QQN7_CLOBO Sensor protein EC=2.7.13.3 318 6e-85 >C0ZJT4.1 C0ZJT4_BREBN Two-component sensor histidine kinase EC=2.7.3.- Length = 474 Score = 493 bits (1270), Expect = e-137, Method: Compositional matrix adjust. Identities = 256/460 (55%), Positives = 320/460 (69%), Gaps = 2/460 (0%) Query: 7 LKGIRARXXXXXXXXXXXXXXXXEGVFIAAVHYYYLGSAMETLTSRATTSATFFNKYLEG 66 +KGI++R EG+F AVH YY+G+A E L +R+TT F NKY G Sbjct: 11 MKGIKSRLVLHFGLILLLIVLLLEGLFYWAVHTYYIGTATEALVTRSTTFTNFINKYATG 70 Query: 67 YSINERARYILENLSPDESSKVEVLSPEGKVIINSFGFASSERIDTPDVKAALASGKGTY 126 Y + ++ARYILEN+S E +K+EVL P GKVI+NS+GF +SE I+TPDV AL G Y Sbjct: 71 YRLKDKARYILENVSNQEYAKIEVLDPGGKVILNSYGFQTSEIINTPDVMDALKGQSGLY 130 Query: 127 QSLTPGKEERILAVSIALKESGTSIGVLRYSVSAEPLYSVIVKILINAAWVGLLVIAFGF 186 +P ER++AVS L SG +GVLRY++SAEPLY + +I + A VG V+ F Sbjct: 131 IGKSPQSRERVIAVSNPLTYSGEFVGVLRYTISAEPLYQAVNRIALYGAGVGTGVVILAF 190 Query: 187 LLSVIIAKRIVEPIQQLTGVAKEMATGNFAVRAKKRHDDEVGTLAVTLNYMAEEMVKSEK 246 LS+++AKRIV+PI+ LT AK+MA GNF+VRA KR DDEVGTLA T NYMA E+ K+EK Sbjct: 191 ALSLLMAKRIVDPIEDLTNAAKQMAEGNFSVRAPKRFDDEVGTLADTFNYMATEIGKNEK 250 Query: 247 IKYDFISSVTHELRTPLTSIKGWGETLLVGDLSDTEETLMGLEVMTGETDRLIGLVEDLL 306 +K DFISSV+HELRTPLTSIKGWGETL+ G L + EET++GLEV++ ETDRLIGLVE+LL Sbjct: 251 LKNDFISSVSHELRTPLTSIKGWGETLISGGLEEPEETMLGLEVISKETDRLIGLVEELL 310 Query: 307 DFSKFQAGELTLELEPYDXXXXXXXXXXQFRYRGSTKQIRLYADIPDEPLPVDGDFNRLK 366 DFSKFQ+GE+ L P D QF R KQI L + P PL V GD NRLK Sbjct: 311 DFSKFQSGEMKLSRVPMDVRELLQDLHLQFSVRAHAKQIELKLETPPTPLIVMGDPNRLK 370 Query: 367 QVFVNLLDNAFKFTPAQGEIRLSA-VSGDTLISITVADNGEGIEESDLEKLGTKFFKGKS 425 QVFVNLLDNA KFTP G I ++A +S D L+ +TV D GEGI DL + KFFKG+S Sbjct: 371 QVFVNLLDNALKFTPQNGSIVIAASLSADRLL-VTVTDTGEGINPEDLPHVTEKFFKGRS 429 Query: 426 RQSGSGLGLAICKEIIEMHGGRLRIESEFTKGTSVIVELP 465 + SGSGLGLAICKEII++H GR + S +GTS++V+LP Sbjct: 430 KLSGSGLGLAICKEIIQLHAGRFSVSSALGQGTSIMVDLP 469 >A4J7U4.1 A4J7U4_DESRM Sensor protein EC=2.7.13.3 Length = 467 Score = 392 bits (1006), Expect = e-107, Method: Compositional matrix adjust. Identities = 217/460 (47%), Positives = 297/460 (64%), Gaps = 2/460 (0%) Query: 7 LKGIRARXXXXXXXXXXXXXXXXEGVFIAAVHYYYLGSAMETLTSRATTSATFFNKYLEG 66 +KGI+ R EG+FI + YY GSA + L SRAT SA F+NKYL Sbjct: 1 MKGIKRRMVWHYVIVIFLTVLVLEGLFIGTIRQYYFGSAEQALVSRATVSANFYNKYLRD 60 Query: 67 YS--INERARYILENLSPDESSKVEVLSPEGKVIINSFGFASSERIDTPDVKAALASGKG 124 Y+ + A+ ILE L DE +++E++ +G V+++S GF ++R+D+PD K ALA G Sbjct: 61 YNFYLKTNAQKILETLPKDEPARIEIIDWQGNVLVDSNGFPRAQRVDSPDFKEALAGKTG 120 Query: 125 TYQSLTPGKEERILAVSIALKESGTSIGVLRYSVSAEPLYSVIVKILINAAWVGLLVIAF 184 ++ ERILAVS LK+ S+GVLRY VS E L++V++KI + + VGLLV+ Sbjct: 121 VWRGKNDITGERILAVSNPLKDGNRSVGVLRYVVSLEALHNVVLKITLVSVTVGLLVVLL 180 Query: 185 GFLLSVIIAKRIVEPIQQLTGVAKEMATGNFAVRAKKRHDDEVGTLAVTLNYMAEEMVKS 244 +S+++A+ IV P+Q++T VA +MA G+F+V+A KR DDEVG LA TLNYM+EE++KS Sbjct: 181 AVGVSLVLARSIVIPLQEVTRVAGQMAKGDFSVKATKREDDEVGKLADTLNYMSEEILKS 240 Query: 245 EKIKYDFISSVTHELRTPLTSIKGWGETLLVGDLSDTEETLMGLEVMTGETDRLIGLVED 304 +K+K DFISS++HELRTPLTSIKGWGETL +L D EE GL ++ ETDR+IGLVE+ Sbjct: 241 DKMKNDFISSISHELRTPLTSIKGWGETLFGEELQDREEVKEGLNIICKETDRMIGLVEE 300 Query: 305 LLDFSKFQAGELTLELEPYDXXXXXXXXXXQFRYRGSTKQIRLYADIPDEPLPVDGDFNR 364 LLDFS+FQ+G + L LE + Q+ R K+I + D + GD NR Sbjct: 301 LLDFSRFQSGRIKLNLEKININSLLTEVIQQYAIRVRQKKIEMPYQFNDSVPEITGDRNR 360 Query: 365 LKQVFVNLLDNAFKFTPAQGEIRLSAVSGDTLISITVADNGEGIEESDLEKLGTKFFKGK 424 LKQVF+NLLDNA KFTP G++++S + I I ++GEGI DL ++ KF+K Sbjct: 361 LKQVFINLLDNAVKFTPFCGKVQISTEYSEGTIKIDFVNSGEGIRSEDLPRVTEKFYKAN 420 Query: 425 SRQSGSGLGLAICKEIIEMHGGRLRIESEFTKGTSVIVEL 464 + + GSGLGLAI KEII +H G L IES + T V V L Sbjct: 421 ANRPGSGLGLAIVKEIINLHQGDLHIESIPGQNTRVTVIL 460 >B1KUF5.1 B1KUF5_CLOBM Sensor protein EC=2.7.13.3 Length = 464 Score = 319 bits (817), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 174/436 (39%), Positives = 266/436 (61%), Gaps = 1/436 (0%) Query: 30 EGVFIAAVHYYYLGSAMETLTSRATTSATFFNKYLEGYSINERARYILENLSPDESSKVE 89 E + I +YY + + ++++ TSA F+NKY + + ++ S++V+ Sbjct: 26 EFLLILFTRHYYYNNLEDAISNQIKTSAEFYNKYFSNSPLEDNVLDNVDVFWRQTSAQVQ 85 Query: 90 VLSPEGKVIINSFGFASSERIDTPDVKAALASGKGTYQSLTPGKEERILAVSIALKESGT 149 ++ +GKV+++S G ++ +I T D++ AL GKG + ++AV+ LK Sbjct: 86 IIDTKGKVLMDSIGVSNKSQIKTSDIQKALKGGKGVWIGKVDYDTSGVMAVTYPLKSDNQ 145 Query: 150 SIGVLRYSVSAEPLYSVIVKILINAAWVGLLVIAFGFLLSVIIAKRIVEPIQQLTGVAKE 209 +GVLR+ S + S I +I + +GL+VI L+S+ +A I EPI++LT VA + Sbjct: 146 IVGVLRFITSLRYVNSDIARISLGFLLIGLVVILISGLVSLFLANSITEPIKELTYVANK 205 Query: 210 MATGNFAVRAKKRHDDEVGTLAVTLNYMAEEMVKSEKIKYDFISSVTHELRTPLTSIKGW 269 MA+GNF V+++K DDE G L+ TLNYMA+E+VK +++K +FISSV+HELRTPLTSIKGW Sbjct: 206 MASGNFKVKSEKMFDDEFGELSDTLNYMADEIVKKDQLKNEFISSVSHELRTPLTSIKGW 265 Query: 270 GETLLVGDLSDTEETLMGLEVMTGETDRLIGLVEDLLDFSKFQAGELTLELEPYDXXXXX 329 TL ++ D E GL+++ E++RL G+VE+LLDFSKF +G++ L E + Sbjct: 266 AITLNSNEV-DKEILKDGLKIIEDESERLSGMVEELLDFSKFVSGKMRLNKEEINICEII 324 Query: 330 XXXXXQFRYRGSTKQIRLYADIPDEPLPVDGDFNRLKQVFVNLLDNAFKFTPAQGEIRLS 389 Q +I A ++ + GD NR+KQV +NLLDNAFKFTP G + LS Sbjct: 325 DTVRKQLEPYAYRNRINFKATCINKLPNIYGDRNRIKQVLINLLDNAFKFTPEGGLVELS 384 Query: 390 AVSGDTLISITVADNGEGIEESDLEKLGTKFFKGKSRQSGSGLGLAICKEIIEMHGGRLR 449 + I+I V D G GI + DL ++ KF+KG S +S +G+GL+IC EII++H G L Sbjct: 385 TKYEEEYITIVVKDTGVGISKEDLPRVKEKFYKGNSGKSKNGIGLSICDEIIKLHNGVLH 444 Query: 450 IESEFTKGTSVIVELP 465 IESE KGT++ ++LP Sbjct: 445 IESEENKGTTISIKLP 460 >C3KZH3.1 C3KZH3_CLOB6 Sensor histidine kinase EC=2.7.3.- Length = 464 Score = 318 bits (816), Expect = 6e-85, Method: Compositional matrix adjust. Identities = 173/440 (39%), Positives = 267/440 (60%), Gaps = 1/440 (0%) Query: 30 EGVFIAAVHYYYLGSAMETLTSRATTSATFFNKYLEGYSINERARYILENLSPDESSKVE 89 E + I +YY + + ++++ TSA F+NKY + + ++ S++V+ Sbjct: 26 EFLLIIFTRHYYYNNLEDAISNQIKTSAEFYNKYFSNSPLEDNVLDNVDVFWRQTSAQVQ 85 Query: 90 VLSPEGKVIINSFGFASSERIDTPDVKAALASGKGTYQSLTPGKEERILAVSIALKESGT 149 ++ +GKV+++S G ++ +I T D++ AL KG + ++AV+ LK Sbjct: 86 IIDTKGKVLMDSIGVSNKSQIKTSDIQKALKGEKGVWIGKVDYDTSGVMAVTYPLKSDNQ 145 Query: 150 SIGVLRYSVSAEPLYSVIVKILINAAWVGLLVIAFGFLLSVIIAKRIVEPIQQLTGVAKE 209 +GVLR+ S + S I +I + +GL+VI L+S+ +A I EPI++LT VA + Sbjct: 146 IVGVLRFITSLRYVNSDIARISLGFLLIGLVVILISGLVSLFLANSITEPIKELTDVANK 205 Query: 210 MATGNFAVRAKKRHDDEVGTLAVTLNYMAEEMVKSEKIKYDFISSVTHELRTPLTSIKGW 269 MA+GNF V+++K DDE G L+ TLNYMA+E+VK +++K +FISSV+HELRTPLTSIKGW Sbjct: 206 MASGNFKVKSEKMFDDEFGELSDTLNYMADEIVKKDQLKNEFISSVSHELRTPLTSIKGW 265 Query: 270 GETLLVGDLSDTEETLMGLEVMTGETDRLIGLVEDLLDFSKFQAGELTLELEPYDXXXXX 329 TL ++ D E GL+++ E++RL G+VE+LLDFSKF +G++ L E + Sbjct: 266 AITLNSNEV-DKEILKDGLKIIEDESERLSGMVEELLDFSKFVSGKMKLNKEEINICEII 324 Query: 330 XXXXXQFRYRGSTKQIRLYADIPDEPLPVDGDFNRLKQVFVNLLDNAFKFTPAQGEIRLS 389 Q +I A ++ + GD NR+KQV +NLLDNAFKFTP G + L+ Sbjct: 325 DTVRKQLEPYAYRNRINFKATCINKLPNIYGDRNRIKQVLINLLDNAFKFTPEGGLVELN 384 Query: 390 AVSGDTLISITVADNGEGIEESDLEKLGTKFFKGKSRQSGSGLGLAICKEIIEMHGGRLR 449 + I+I V D G GI + DL ++ KF+KG S +S +G+GL+IC EII++H G L Sbjct: 385 TKCEEEYITIVVKDTGVGINKEDLPRVKEKFYKGNSGKSKNGIGLSICDEIIKLHNGVLH 444 Query: 450 IESEFTKGTSVIVELPRYRM 469 IESE KGT++ V+LP ++ Sbjct: 445 IESEENKGTTISVKLPMIKL 464 >B1QQN7.1 B1QQN7_CLOBO Sensor protein EC=2.7.13.3 Length = 464 Score = 318 bits (816), Expect = 6e-85, Method: Compositional matrix adjust. Identities = 173/440 (39%), Positives = 267/440 (60%), Gaps = 1/440 (0%) Query: 30 EGVFIAAVHYYYLGSAMETLTSRATTSATFFNKYLEGYSINERARYILENLSPDESSKVE 89 E + I +YY + + ++++ TSA F+NKY + + ++ S++V+ Sbjct: 26 EFLLIIFTRHYYYNNLEDAISNQIKTSAEFYNKYFSNSPLEDNVLDNVDVFWRQTSAQVQ 85 Query: 90 VLSPEGKVIINSFGFASSERIDTPDVKAALASGKGTYQSLTPGKEERILAVSIALKESGT 149 ++ +GKV+++S G ++ +I T D++ AL KG + ++AV+ LK Sbjct: 86 IIDTKGKVLMDSIGVSNKSQIKTSDIQKALKGEKGVWIGKVDYDTSGVMAVTYPLKSDNQ 145 Query: 150 SIGVLRYSVSAEPLYSVIVKILINAAWVGLLVIAFGFLLSVIIAKRIVEPIQQLTGVAKE 209 +GVLR+ S + S I +I + +GL+VI L+S+ +A I EPI++LT VA + Sbjct: 146 IVGVLRFITSLRYVNSDIARISLGFLLIGLVVILISGLVSLFLANSITEPIKELTDVANK 205 Query: 210 MATGNFAVRAKKRHDDEVGTLAVTLNYMAEEMVKSEKIKYDFISSVTHELRTPLTSIKGW 269 MA+GNF V+++K DDE G L+ TLNYMA+E+VK +++K +FISSV+HELRTPLTSIKGW Sbjct: 206 MASGNFKVKSEKMFDDEFGELSDTLNYMADEIVKKDQLKNEFISSVSHELRTPLTSIKGW 265 Query: 270 GETLLVGDLSDTEETLMGLEVMTGETDRLIGLVEDLLDFSKFQAGELTLELEPYDXXXXX 329 TL ++ D E GL+++ E++RL G+VE+LLDFSKF +G++ L E + Sbjct: 266 AITLNSNEV-DKEILKDGLKIIEDESERLSGMVEELLDFSKFVSGKMKLNKEEINICEII 324 Query: 330 XXXXXQFRYRGSTKQIRLYADIPDEPLPVDGDFNRLKQVFVNLLDNAFKFTPAQGEIRLS 389 Q +I A ++ + GD NR+KQV +NLLDNAFKFTP G + L+ Sbjct: 325 DTVRKQLEPYAYRNRINFKATCINKLPNIYGDRNRIKQVLINLLDNAFKFTPEGGLVELN 384 Query: 390 AVSGDTLISITVADNGEGIEESDLEKLGTKFFKGKSRQSGSGLGLAICKEIIEMHGGRLR 449 + I+I V D G GI + DL ++ KF+KG S +S +G+GL+IC EII++H G L Sbjct: 385 TKCEEEYITIVVKDTGVGINKEDLPRVKEKFYKGNSGKSKNGIGLSICDEIIKLHNGVLH 444 Query: 450 IESEFTKGTSVIVELPRYRM 469 IESE KGT++ V+LP ++ Sbjct: 445 IESEENKGTTISVKLPMIKL 464 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.135 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,475,470,059 Number of extensions: 101235001 Number of successful extensions: 405913 Number of sequences better than 1.0e-05: 30614 Number of HSP's gapped: 348269 Number of HSP's successfully gapped: 30901 Length of query: 470 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 331 Effective length of database: 1,751,175,118 Effective search space: 579638964058 Effective search space used: 579638964058 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 133 (55.8 bits)