BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0557.0082.p (555 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KGK1.1 B3KGK1_9BACI Chromosome segregation protein SMC 770 0.0 B1DME2.1 B1DME2_9BACL Chromosome segregation protein SMC 656 0.0 C0ZFN9.1 C0ZFN9_BREBN Chromosome partition protein SMC 486 e-135 Q9KA07.1 Q9KA07_BACHD Chromosome segregation SMC protein 441 e-122 C1P6S9.1 C1P6S9_BACCO Chromosome segregation protein SMC 422 e-116 >B3KGK1.1 B3KGK1_9BACI Chromosome segregation protein SMC Length = 1061 Score = 770 bits (1988), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/546 (71%), Positives = 442/546 (80%) Query: 1 MFLKRIELAGFKSFADKTEMEFVRGITAVVGPNGSGKSNISDGIRWVLGEQSAKSLRGGK 60 MFLKRIELAGFKSFADKTEMEFVRGITAVVGPNGSGKSNISDGIRWVLGEQSAKSLRGGK Sbjct: 1 MFLKRIELAGFKSFADKTEMEFVRGITAVVGPNGSGKSNISDGIRWVLGEQSAKSLRGGK 60 Query: 61 MEDIIFAGSDARKAVNYGEVSLTLDNEDHALPLDFSEVTVTRRVHRSGESEYLINKQACR 120 MEDIIFAGSDARKAVNYGEVSLTLDNEDH LPLDF+EVTVTRRVHRSG+SEY IN+Q+CR Sbjct: 61 MEDIIFAGSDARKAVNYGEVSLTLDNEDHVLPLDFNEVTVTRRVHRSGDSEYFINRQSCR 120 Query: 121 LKDITELFMDTGIGREAYSIIGQGRIEEILSTRSEDRRGIFEEASGIVKYKSRKRDAARK 180 LKDITELFMDTGIG+EAYSIIGQGRIEEILSTRSEDRRGIFEEASGIVKYKSRK+++ RK Sbjct: 121 LKDITELFMDTGIGKEAYSIIGQGRIEEILSTRSEDRRGIFEEASGIVKYKSRKKESVRK 180 Query: 181 LDETEQNLLRIHDLISELEDQVGPLKEQSEKAIRYKELREQLKQLEISVYVHQIEGIHTA 240 LDETEQNLLRIHDL++ELEDQ+GPLKEQSEKAIRYKELRE+LK EIS+YV+QIE IHT+ Sbjct: 181 LDETEQNLLRIHDLVTELEDQIGPLKEQSEKAIRYKELREELKHKEISLYVYQIEQIHTS 240 Query: 241 WKEGNDRLEVLRDEQLELSTIVSAHDAKLESGXXXXXXXXXXXXXXXXXXXRYSEANEKS 300 W E N +LE L++EQL LST+VSAHDAKLES ++SE EKS Sbjct: 241 WSEANAKLEQLKEEQLALSTVVSAHDAKLESDRSALRQLEQEVEDLQSQLLQFSELFEKS 300 Query: 301 EGYGELLKERRRNLESNREQLLATLGSVGERSEGRQRELAELEHKLQQTRLALEELRTQI 360 EGYGE+LKERRRNLE REQL +L S R E R ELA ++ KLQ + L ++R Q+ Sbjct: 301 EGYGEVLKERRRNLERTREQLEESLHSGDHRLEERVGELARMKSKLQDLQQELTQVRDQL 360 Query: 361 ADEESRLEGVAGGINXXXXXXXXXXXXXXMNLMAQARNEIRYADQQKESLERRMSRSQEE 420 + EE++L GV GGI+ MN MAQARNEIRYADQQ+E+L+RRM+R+QEE Sbjct: 361 SAEEAKLVGVTGGISQQQEESLKGNLLELMNQMAQARNEIRYADQQQEALDRRMNRAQEE 420 Query: 421 SGKWTTRLKELTSAQNGLKDKIAGLGKEISSLRNAYITESEQTSKRQKLLEETQSGLRKW 480 SGKW ++L ++ + I GKEI+ LR+ YI+ESE+ QKL EETQ LRKW Sbjct: 421 SGKWEALKEDLLRRKDSIDRSIERFGKEIADLRSGYISESERYQSLQKLQEETQGALRKW 480 Query: 481 EQKREAQVSRHETMKEMQDDFDGFMLGVKEVLKGARKGQLSGVHGAVAELISVPEKLEMA 540 EQKREAQ+SR +TMKE+QDDFDGFMLGVKEVLK +RK L GVHGAVAELI VPEKLE+A Sbjct: 481 EQKREAQISRRDTMKELQDDFDGFMLGVKEVLKASRKSVLHGVHGAVAELIRVPEKLELA 540 Query: 541 VXXXXG 546 + G Sbjct: 541 METALG 546 >B1DME2.1 B1DME2_9BACL Chromosome segregation protein SMC Length = 1114 Score = 656 bits (1692), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/550 (62%), Positives = 412/550 (74%), Gaps = 4/550 (0%) Query: 1 MFLKRIELAGFKSFADKTEMEFVRGITAVVGPNGSGKSNISDGIRWVLGEQSAKSLRGGK 60 MFLKRIEL+GFKSFADKTEMEFV GITAVVGPNGSGKSNISDGIRWVLGEQSAKSLRGGK Sbjct: 1 MFLKRIELSGFKSFADKTEMEFVTGITAVVGPNGSGKSNISDGIRWVLGEQSAKSLRGGK 60 Query: 61 MEDIIFAGSDARKAVNYGEVSLTLDNEDHALPLDFSEVTVTRRVHRSGESEYLINKQACR 120 MEDIIFAGSDARKAVNYGEVSLTLDN D ALPL+++EVTVTRRVHRSG+SEY+INKQ+CR Sbjct: 61 MEDIIFAGSDARKAVNYGEVSLTLDNGDGALPLEYNEVTVTRRVHRSGDSEYMINKQSCR 120 Query: 121 LKDITELFMDTGIGREAYSIIGQGRIEEILSTRSEDRRGIFEEASGIVKYKSRKRDAARK 180 LKDITELFMDTGIG+EAYSIIGQGRIEEILSTRSEDRRGIFEEASGIVKYKSRKR+A RK Sbjct: 121 LKDITELFMDTGIGKEAYSIIGQGRIEEILSTRSEDRRGIFEEASGIVKYKSRKREAQRK 180 Query: 181 LDETEQNLLRIHDLISELEDQVGPLKEQSEKAIRYKELREQLKQLEISVYVHQIEGIHTA 240 L++TE NLLRIHDL++ELEDQV PL+ QSEKAI +K+LREQLK EIS+YVH IE ++ + Sbjct: 181 LEDTENNLLRIHDLVTELEDQVEPLRIQSEKAIHFKQLREQLKTQEISMYVHNIENVYGS 240 Query: 241 WKEGNDRLEVLRDEQLELSTIVSAHDAKLESGXXXXXXXXXXXXXXXXXXXRYSEANEKS 300 W E N +LE L+ EQLELST+VS HDA LE YSE EK Sbjct: 241 WSEANTKLERLKHEQLELSTVVSKHDAHLEKDRQVLRELEEALDRLHGDMLHYSEEYEKC 300 Query: 301 EGYGELLKERRRNLESNREQLLATLGSVGERSEGRQRELAELEHKLQQTRLALEELRTQI 360 EG+GE+LKER++NLE N++QL T+ + ER E AE ++ L L EL+ ++ Sbjct: 301 EGFGEVLKERKKNLEQNKKQLEETISAQDERIAALTSEEAEFRNRAAVLELQLAELKQKL 360 Query: 361 ADEESRLEGVAGGINXXXXXXXXXXXXXXMNLMAQARNEIRYADQQKESLERRMSRSQEE 420 A EE+ L GV+GG ++ MAQ RNEIRYA QQ+E+++RRM R +E Sbjct: 361 AVEENNLIGVSGGTAVDAEEMLKGELLEVLSTMAQLRNEIRYAAQQQEAVQRRMERLSDE 420 Query: 421 SGKWTTRLKELTSAQNGLKDKIAGLGKEISSLRNAYITESEQTSKRQKLLEETQSGLRKW 480 KWT + ++L + + L+ ++ IS R YI ++E+ + ++ E+ + LRKW Sbjct: 421 EAKWTEQQRKLNARRAELEKQLEATLDAISKARTKYIDQAEKAKELGQISEDATAALRKW 480 Query: 481 EQKREAQVSRHETMKEMQDDFDGFMLGVKEVLKGARK----GQLSGVHGAVAELISVPEK 536 EQK +AQVSR +TMKEMQD DGFM GV+EVLK +RK G +SGVHGAVAEL+ VPE+ Sbjct: 481 EQKLDAQVSRRDTMKEMQDALDGFMHGVREVLKASRKSSGSGGISGVHGAVAELVRVPER 540 Query: 537 LEMAVXXXXG 546 +E AV G Sbjct: 541 IETAVETALG 550 >C0ZFN9.1 C0ZFN9_BREBN Chromosome partition protein SMC Length = 1190 Score = 486 bits (1250), Expect = e-135, Method: Compositional matrix adjust. Identities = 270/550 (49%), Positives = 365/550 (66%), Gaps = 10/550 (1%) Query: 1 MFLKRIELAGFKSFADKTEMEFVRGITAVVGPNGSGKSNISDGIRWVLGEQSAKSLRGGK 60 M+LKR+ELAGFKSFAD+TE+EFV G+TAVVGPNGSGKSN+SD IRWVLGEQSAKSLRG K Sbjct: 1 MYLKRLELAGFKSFADRTELEFVPGVTAVVGPNGSGKSNVSDSIRWVLGEQSAKSLRGAK 60 Query: 61 MEDIIFAGSDARKAVNYGEVSLTLDNEDHALPLDFSEVTVTRRVHRSGESEYLINKQACR 120 MEDIIFAGSD RK VN+ EV+LTLDN D +L +++SEV+VTRRV+RSG+SEY IN ++CR Sbjct: 61 MEDIIFAGSDKRKPVNFAEVTLTLDNTDRSLDVEYSEVSVTRRVYRSGDSEYYINNRSCR 120 Query: 121 LKDITELFMDTGIGREAYSIIGQGRIEEILSTRSEDRRGIFEEASGIVKYKSRKRDAARK 180 LKDI E+FMDTG+G+EAYSIIGQG+IEEILST+SEDRRGIFEEA+GIVKYK+RKR+A +K Sbjct: 121 LKDIMEMFMDTGLGKEAYSIIGQGKIEEILSTKSEDRRGIFEEAAGIVKYKTRKREAEKK 180 Query: 181 LDETEQNLLRIHDLISELEDQVGPLKEQSEKAIRYKELREQLKQLEISVYVHQIEGIHTA 240 LD+TEQNL+RIHD++SE+ +Q+GPL+EQ+E A YKEL +L + E+++YV QIE HT Sbjct: 181 LDDTEQNLVRIHDIVSEITEQIGPLQEQAETAKTYKELHRKLVEHEVALYVQQIEVAHTK 240 Query: 241 WKEGNDRLEVLRDEQLELSTIVSAHDAKLESGXXXXXXXXXXXXXXXXXXXRYSEANEKS 300 W+ R+E L+ + +T S +A LE SE EK Sbjct: 241 WEAATGRVEELKHLLIGQTTEASKQEADLEQARFHVTQIDQSIEELQQVLLTVSEETEKV 300 Query: 301 EGYGELLKERRRNLESNREQLLATLGSVGERSEGRQRELAELEHKLQQTRLALEELRTQI 360 EG E+L+ER RNL +NR+Q + + + E+ G + ELAE + + ++ + E + Sbjct: 301 EGQREVLRERMRNLNANRQQTMEQMHRITEKQHGLEAELAEEQERAKEADRRMTEAHASL 360 Query: 361 ADEESRLEGVAGGINXXXXXXXXXXXXXXMNLMAQARNEIRYADQ----QKESLERRMSR 416 + E + + + +N MA RNE R+ +Q + +ER++S Sbjct: 361 QEAEGQFFSMVQSLT-DDVERLKSDYFEKLNEMANLRNENRHQEQLLKTSEARVERQLSG 419 Query: 417 SQEESGKWTTRLKELTSAQNGLKDKIAGLGKEISSLRNAYITESEQTSKRQKLLEETQSG 476 ++ + RL +L+ Q+ L +KI +E + +R + E + Q LE + Sbjct: 420 KKQLDDEEEQRLAQLSQLQDQL-EKIVSTIQE-TGVRYKELVEG--MREGQARLETARRE 475 Query: 477 LRKWEQKREAQVSRHETMKEMQDDFDGFMLGVKEVLKGARKGQLSGVHGAVAELISVPEK 536 LR WEQKREA SR + +KEMQ +F GF GVKE+LK +G G+HGAVAEL+ VP++ Sbjct: 476 LRHWEQKREAAKSRFDLLKEMQSEFAGFQQGVKEILKARERG-FKGIHGAVAELVVVPQQ 534 Query: 537 LEMAVXXXXG 546 E A+ G Sbjct: 535 YETAMEVALG 544 >Q9KA07.1 Q9KA07_BACHD Chromosome segregation SMC protein Length = 1188 Score = 441 bits (1135), Expect = e-122, Method: Compositional matrix adjust. Identities = 245/546 (44%), Positives = 351/546 (64%), Gaps = 2/546 (0%) Query: 1 MFLKRIELAGFKSFADKTEMEFVRGITAVVGPNGSGKSNISDGIRWVLGEQSAKSLRGGK 60 MFLKR+E+ GFKSFA++ +EFV+G+TAVVGPNGSGKSNISDGIRWVLGEQSAKSLRG K Sbjct: 1 MFLKRLEIVGFKSFAEQMTVEFVKGVTAVVGPNGSGKSNISDGIRWVLGEQSAKSLRGSK 60 Query: 61 MEDIIFAGSDARKAVNYGEVSLTLDNEDHALPLDFSEVTVTRRVHRSGESEYLINKQACR 120 M+DIIFAGSD RK +N+ E+SL LDNED +P+D+SEV+VTRRV+RSGESEYL+N+Q CR Sbjct: 61 MQDIIFAGSDTRKPLNFAEISLVLDNEDQHIPIDYSEVSVTRRVYRSGESEYLLNRQPCR 120 Query: 121 LKDITELFMDTGIGREAYSIIGQGRIEEILSTRSEDRRGIFEEASGIVKYKSRKRDAARK 180 LKDI +LFMD+G+GREAYSIIGQG++EEILS+++EDRR IFEEA+G++KYK+RK+ A ++ Sbjct: 121 LKDIVDLFMDSGLGREAYSIIGQGKVEEILSSKAEDRRVIFEEAAGVLKYKTRKQQAEKR 180 Query: 181 LDETEQNLLRIHDLISELEDQVGPLKEQSEKAIRYKELREQLKQLEISVYVHQIEGIHTA 240 LD+T++NL R+ D++ ELE QV PLK Q+ A Y E +++L+Q+EI+V V+ I+ IHT Sbjct: 181 LDDTQENLNRVEDILHELEGQVEPLKIQASVAKDYLEKKKELEQVEIAVLVYDIDRIHTE 240 Query: 241 WKEGNDRLEVLRDEQLELSTIVSAHDAKLESGXXXXXXXXXXXXXXXXXXXRYSEANEKS 300 W + + L++L+++ L +S + ++ SE EK Sbjct: 241 WNKAKEALDLLKEQHRALEQQISEKEQSVQGLKQQIAQLDEEAQIAQQQLLSASETLEKR 300 Query: 301 EGYGELLKERRRNLESNREQLLATLGSVGERSEGRQRELAELEHKLQQTRLALEELRTQI 360 EG ++LKER +N NREQLL T+ E+ + LA+ E Q+ + L +I Sbjct: 301 EGRRDVLKERLKNAAENREQLLQTIREGEEKVASLKVHLAKEEEAKQKAYEQMTALEAEI 360 Query: 361 ADEESRLEGVAGGINXXXXXXXXXXXXXXMNLMAQARNEIRYADQQKESLERRMSRSQEE 420 ++E L G + +N A RNE RY ++Q + L+++ R E Sbjct: 361 RNQEKALHGNEKELE-ETVDRLKSDYIELLNEQASLRNETRYLEEQLQQLQQKQERLIRE 419 Query: 421 SGKWTTRLKELTSAQNGLKDKIAGLGKEISSLRNAYITESEQTSKRQKLLEETQSGLRKW 480 + + + KEL + + + + K++ L + Y + + + ++ E+ + L + Sbjct: 420 NEAYFQKRKELEAQEEQERMQFEAKEKQLHRLVDEYRNQQRKVEQVTRVYEQKEKQLYEA 479 Query: 481 EQKREAQVSRHETMKEMQDDFDGFMLGVKEVLKGARKGQLSGVHGAVAELISVPEKLEMA 540 Q + SR + ++EMQ DF GF GVKEVLK AR L G+ GAVAEL++VP+ E A Sbjct: 480 YQLIQRLTSRKDVLEEMQADFSGFFQGVKEVLK-ARHSTLKGIVGAVAELVTVPKPYETA 538 Query: 541 VXXXXG 546 + G Sbjct: 539 IEIALG 544 >C1P6S9.1 C1P6S9_BACCO Chromosome segregation protein SMC Length = 1190 Score = 422 bits (1085), Expect = e-116, Method: Compositional matrix adjust. Identities = 238/550 (43%), Positives = 343/550 (62%), Gaps = 10/550 (1%) Query: 1 MFLKRIELAGFKSFADKTEMEFVRGITAVVGPNGSGKSNISDGIRWVLGEQSAKSLRGGK 60 MFLKR+++ GFKSFAD+ EFV G+TAVVGPNGSGKSN+ D +RWVLGEQSAKSLRGGK Sbjct: 1 MFLKRLDVIGFKSFADRISFEFVPGVTAVVGPNGSGKSNVIDAVRWVLGEQSAKSLRGGK 60 Query: 61 MEDIIFAGSDARKAVNYGEVSLTLDNEDHALPLDFSEVTVTRRVHRSGESEYLINKQACR 120 MED+IFAGSD RK +N+ EV+LTL+NE ALP+D+ EV+VTRRV+RSGESE+ INKQ CR Sbjct: 61 MEDVIFAGSDTRKPLNFAEVTLTLENEGRALPIDYQEVSVTRRVYRSGESEFYINKQQCR 120 Query: 121 LKDITELFMDTGIGREAYSIIGQGRIEEILSTRSEDRRGIFEEASGIVKYKSRKRDAARK 180 LKDI ELFMD+G+G+EA+SII QG++EEIL++++E+RR IFEEA+G++KYK+RK+ A K Sbjct: 121 LKDIVELFMDSGLGKEAFSIISQGKVEEILNSKAEERRSIFEEAAGVLKYKTRKKKAEVK 180 Query: 181 LDETEQNLLRIHDLISELEDQVGPLKEQSEKAIRYKELREQLKQLEISVYVHQIEGIHTA 240 L ET+ NL R+ D++ ELE Q+ PLK Q+ A Y E +E LK EI+V ++IE +H Sbjct: 181 LAETQDNLNRVSDILYELESQLEPLKMQASVAKDYLEQKEALKNYEIAVLAYEIESLHGE 240 Query: 241 WKEGNDRLEVLRDEQLELSTIVSAHDAKLESGXXXXXXXXXXXXXXXXXXXRYSEANEKS 300 W+ +LE RD++ LS+ + +A+L + +E EK Sbjct: 241 WESLKSQLEAHRDKEAGLSSEIRKQEAQLAEKRNQLDALDESIQDLQNVLLQATEELEKL 300 Query: 301 EGYGELLKERRRNLESNREQLLATLGSVGERSEGRQRELAELEHKLQQTRL----ALEEL 356 EG E+LKER++N N+ QL + +E +EL + KL QT AL L Sbjct: 301 EGQKEVLKERKKNASENKAQLEKNINE----AENALKELEAQKEKLLQTAAENEQALSSL 356 Query: 357 RTQIADEESRLEGVAGGINXXXXXXXXXXXXXXMNLMAQARNEIRYADQQKESLERRMSR 416 + + ++E+ L ++ + +N A +NE R QQ ++ R+SR Sbjct: 357 KESVKEKEAGLFRLSTNLE-EKIESLKSDYIELLNEQASGKNEKRLLMQQVQTSLNRLSR 415 Query: 417 SQEESGKWTTRLKELTSAQNGLKDKIAGLGKEISSLRNAYITESEQTSKRQKLLEETQSG 476 + ++ K+ +++ + ++A + +E+ + AY+ + Q ++ +S Sbjct: 416 LEADNRKYVDEREKVREKKKMATGRLAKIKQELEAAAGAYMEKQRQLESVNSRYQKQESN 475 Query: 477 LRKWEQKREAQVSRHETMKEMQDDFDGFMLGVKEVLKGARKGQLSGVHGAVAELISVPEK 536 L + Q + SR ET++EM++D+ GF GV+E+LK AR QL G+ GAVAEL+ VP Sbjct: 476 LYQAYQYLQKAKSRKETLEEMEEDYTGFYQGVREILK-ARGKQLEGIEGAVAELVRVPAP 534 Query: 537 LEMAVXXXXG 546 E AV G Sbjct: 535 YEKAVETALG 544 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.312 0.130 0.350 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,778,440,728 Number of extensions: 108462315 Number of successful extensions: 528814 Number of sequences better than 1.0e-05: 1897 Number of HSP's gapped: 525681 Number of HSP's successfully gapped: 1916 Length of query: 555 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 414 Effective length of database: 1,732,333,088 Effective search space: 717185898432 Effective search space used: 717185898432 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 134 (56.2 bits)