BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0557.0029.p (327 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KBH3.1 B3KBH3_9BACI Diaminopimelate dehydrogenase EC=1.4.1.16 573 e-162 C0GJY4.1 C0GJY4_9FIRM Diaminopimelate dehydrogenase EC=1.4.1.16 452 e-125 A6UP31.1 A6UP31_METVS Diaminopimelate dehydrogenase EC=1.4.1.16 446 e-123 A3IBY2.1 A3IBY2_9BACI Meso-diaminopimelate dehydrogenase 446 e-123 B1HPA8.1 B1HPA8_LYSSC Meso-diaminopimelate D-dehydrogenase EC=1.... 444 e-123 >B3KBH3.1 B3KBH3_9BACI Diaminopimelate dehydrogenase EC=1.4.1.16 Length = 327 Score = 573 bits (1478), Expect = e-162, Method: Compositional matrix adjust. Identities = 269/327 (82%), Positives = 302/327 (92%) Query: 1 VNTTIKVGISGYGNLGRGVHQAIAQNPDMELVAIFTRRDPQQLQTPPGVHFEHISAADQY 60 +N TIKVGI GYGNLG+GV +AI QNPD+ELVAIFTRRDPQQ+ G FEHIS A+QY Sbjct: 1 MNATIKVGIVGYGNLGKGVQKAIGQNPDLELVAIFTRRDPQQMPANSGARFEHISVAEQY 60 Query: 61 IGRIDVMILCGGSATDLPEQTPQLAAMFNTVDSFDTHAKIPEFFQSVNQAALGGGRLSVI 120 IG+IDVMILCGGSATDLPEQTPQLA+MFNTVDSFDTHAKIPEFFQ VN+AA+GGG +SVI Sbjct: 61 IGKIDVMILCGGSATDLPEQTPQLASMFNTVDSFDTHAKIPEFFQEVNKAAMGGGHISVI 120 Query: 121 STGWDPGLFSMNRLLMEAVLPEGQEYTFWGPGVSQGHSDAIRRVPGVKAGVQYTVPVQAV 180 STGWDPGLFSMNRLL EA+LPEG++YTFWG GVSQGHSDAIRRVPGVKAGVQYTVPV+ V Sbjct: 121 STGWDPGLFSMNRLLAEAILPEGKDYTFWGKGVSQGHSDAIRRVPGVKAGVQYTVPVEEV 180 Query: 181 IDGIRAGDTPKLETRQKHRRDCFVVAQEDADREQIRKAIVNMPNYFADYDTTVTFITQEQ 240 I+ IR+G+TP+L TR+KHRRDCFVVA+E AD+EQIR+ IV+MPNYF+DYDTTVTFITQE+ Sbjct: 181 INQIRSGETPELATREKHRRDCFVVAEEGADQEQIRQTIVSMPNYFSDYDTTVTFITQEE 240 Query: 241 LAAEHSGMPHGGFVIRSGVSGNGSKQIAEFGLKLESNPEFTASVLVAYARAAFRLSQEGQ 300 L AEH+GMPHGGFVIRSGV+GNGSKQI EFGLKL+SNPEFTASVLV+YARAA RLS+EGQ Sbjct: 241 LEAEHAGMPHGGFVIRSGVTGNGSKQIVEFGLKLDSNPEFTASVLVSYARAAHRLSREGQ 300 Query: 301 RGAKTVFDIPLGYLSPKSAEELRRGLL 327 +GAKTVFDIPLGYLSPKSAE+LR LL Sbjct: 301 QGAKTVFDIPLGYLSPKSAEQLRSELL 327 >C0GJY4.1 C0GJY4_9FIRM Diaminopimelate dehydrogenase EC=1.4.1.16 Length = 327 Score = 452 bits (1162), Expect = e-125, Method: Compositional matrix adjust. Identities = 210/324 (64%), Positives = 261/324 (80%), Gaps = 1/324 (0%) Query: 5 IKVGISGYGNLGRGVHQAIAQNPDMELVAIFTRRDPQQLQTPPG-VHFEHISAADQYIGR 63 I+VGI GYGNLG+GV A+ Q+PD EL IFTRR P+ +Q+ G V F HI A Y+G+ Sbjct: 4 IRVGIVGYGNLGKGVELALQQSPDFELTGIFTRRAPETMQSVTGNVPFFHIDTAKDYVGK 63 Query: 64 IDVMILCGGSATDLPEQTPQLAAMFNTVDSFDTHAKIPEFFQSVNQAALGGGRLSVISTG 123 IDVMILCGGSATD+PEQ P AAMFNTVDS+DTHAKIPE+ SV++ A G SVISTG Sbjct: 64 IDVMILCGGSATDIPEQGPHFAAMFNTVDSYDTHAKIPEYHASVDEKAKQNGNTSVISTG 123 Query: 124 WDPGLFSMNRLLMEAVLPEGQEYTFWGPGVSQGHSDAIRRVPGVKAGVQYTVPVQAVIDG 183 WDPGLFS+NR++ EA+LP G+EYTFWG GVSQGHSDAIRR+ GVK GVQYT+P+++ ++ Sbjct: 124 WDPGLFSLNRMIAEAILPVGKEYTFWGKGVSQGHSDAIRRIEGVKGGVQYTIPMESALER 183 Query: 184 IRAGDTPKLETRQKHRRDCFVVAQEDADREQIRKAIVNMPNYFADYDTTVTFITQEQLAA 243 +RAG+ P+L TR+KH R+CFVVA++ AD+++I + I MPNYF +Y+T V FI++++L Sbjct: 184 VRAGEDPELSTREKHMRECFVVAEDGADKDKIAETIKTMPNYFDEYETVVHFISEDELKT 243 Query: 244 EHSGMPHGGFVIRSGVSGNGSKQIAEFGLKLESNPEFTASVLVAYARAAFRLSQEGQRGA 303 EH+ MPHGGFVIRSG SG SKQI EF LKL+SNPEFTASVLVAYARAA+RL++EGQ GA Sbjct: 244 EHARMPHGGFVIRSGKSGRDSKQIIEFSLKLQSNPEFTASVLVAYARAAYRLNKEGQSGA 303 Query: 304 KTVFDIPLGYLSPKSAEELRRGLL 327 KTVFD+ YLSPKS +L + LL Sbjct: 304 KTVFDVAPAYLSPKSTAQLMKELL 327 >A6UP31.1 A6UP31_METVS Diaminopimelate dehydrogenase EC=1.4.1.16 Length = 327 Score = 446 bits (1146), Expect = e-123, Method: Compositional matrix adjust. Identities = 203/326 (62%), Positives = 252/326 (77%), Gaps = 2/326 (0%) Query: 4 TIKVGISGYGNLGRGVHQAIAQNPDMELVAIFTRRDPQQLQTPPGVHFEHISAADQYIGR 63 TIK+GI GYGNLG+GV+ AI QNPDMELVA+FTRR ++ + A +Y+ + Sbjct: 2 TIKIGIMGYGNLGKGVYSAIKQNPDMELVAVFTRRPKNSIKIQEDAKIVSVDDAKEYVDK 61 Query: 64 IDVMILCGGSATDLPEQTPQLAAMFNTVDSFDTHAKIPEFFQSVNQAALGGGRLSVISTG 123 IDVMILCGGSATDLP Q P+ A +FNTVDSFDTHAKIPE+F+ V+ A G S IS G Sbjct: 62 IDVMILCGGSATDLPVQGPEFAKLFNTVDSFDTHAKIPEYFEEVDLVAKSNGHTSAISIG 121 Query: 124 WDPGLFSMNRLLMEAVLPEGQEYTFWGPGVSQGHSDAIRRVPGVKAGVQYTVPVQAVIDG 183 WDPGLFS+NR++ EA+LP+G+EYTFWG GVSQGHSDAIRR+ GVK G+QYT+P+ I+ Sbjct: 122 WDPGLFSINRMVSEAILPDGKEYTFWGSGVSQGHSDAIRRISGVKNGIQYTIPLDGAINR 181 Query: 184 IRAGDTPKLETRQKHRRDCFVVAQEDADREQIRKAIVNMPNYFADYDTTVTFITQEQLAA 243 +R+GD P LET++KH R C+VV +E D+ ++ K I MPNYF DY T V FIT+++L Sbjct: 182 VRSGDDPNLETKEKHLRVCYVVLEEGVDKNKVEKEIKEMPNYFLDYTTEVNFITEDELKL 241 Query: 244 EHSGMPHGGFVIRSGVSG--NGSKQIAEFGLKLESNPEFTASVLVAYARAAFRLSQEGQR 301 HSGMPHGGFVIRSG +G +K I EF LKL+SNPEFTAS+LVAYARA F++++EG Sbjct: 242 NHSGMPHGGFVIRSGKTGFNKENKHIVEFSLKLDSNPEFTASILVAYARAVFKMNKEGHF 301 Query: 302 GAKTVFDIPLGYLSPKSAEELRRGLL 327 GAKTVFDI LG+LSPKS+EELR+ LL Sbjct: 302 GAKTVFDISLGHLSPKSSEELRKNLL 327 >A3IBY2.1 A3IBY2_9BACI Meso-diaminopimelate dehydrogenase Length = 326 Score = 446 bits (1146), Expect = e-123, Method: Compositional matrix adjust. Identities = 207/325 (63%), Positives = 251/325 (77%) Query: 3 TTIKVGISGYGNLGRGVHQAIAQNPDMELVAIFTRRDPQQLQTPPGVHFEHISAADQYIG 62 + I+VGI GYGNLGRGV AI+QNPDME+VA+FTRRDP + + A+++ Sbjct: 2 SAIRVGIVGYGNLGRGVEYAISQNPDMEVVAVFTRRDPSTVNVASNASVYLVEDAEKFQN 61 Query: 63 RIDVMILCGGSATDLPEQTPQLAAMFNTVDSFDTHAKIPEFFQSVNQAALGGGRLSVIST 122 IDVMILCGGSATDLPEQ P A FNT+DSFDTHAKIPEFF +V+ AA G++SVIS Sbjct: 62 DIDVMILCGGSATDLPEQGPHFAQWFNTIDSFDTHAKIPEFFDAVDAAAQKSGKVSVISV 121 Query: 123 GWDPGLFSMNRLLMEAVLPEGQEYTFWGPGVSQGHSDAIRRVPGVKAGVQYTVPVQAVID 182 GWDPGLFS+NRLL E+VLP G YTFWG G+SQGHSDA+RR+ GVK VQYT+P++ +D Sbjct: 122 GWDPGLFSLNRLLGESVLPVGTTYTFWGDGLSQGHSDAVRRIEGVKNAVQYTLPIKEAVD 181 Query: 183 GIRAGDTPKLETRQKHRRDCFVVAQEDADREQIRKAIVNMPNYFADYDTTVTFITQEQLA 242 +R G+ P+L TR+KH R+C+VV ++ AD ++ + IV MPNYF +Y+TTV FI++E+ Sbjct: 182 RVRNGENPELTTREKHARECWVVLEDGADAAKVEQKIVTMPNYFDEYNTTVNFISEEEFT 241 Query: 243 AEHSGMPHGGFVIRSGVSGNGSKQIAEFGLKLESNPEFTASVLVAYARAAFRLSQEGQRG 302 A H+GMPHGGFVIRSG SG KQI EF LKLESNP FT+SVLVAYARAA RLSQ G +G Sbjct: 242 ANHTGMPHGGFVIRSGDSGANDKQILEFSLKLESNPNFTSSVLVAYARAAHRLSQAGDKG 301 Query: 303 AKTVFDIPLGYLSPKSAEELRRGLL 327 AKTVFDIP LSPKSA ELR+ LL Sbjct: 302 AKTVFDIPFSLLSPKSAAELRKELL 326 >B1HPA8.1 B1HPA8_LYSSC Meso-diaminopimelate D-dehydrogenase EC=1.4.1.16 Length = 326 Score = 444 bits (1143), Expect = e-123, Method: Compositional matrix adjust. Identities = 207/325 (63%), Positives = 251/325 (77%) Query: 3 TTIKVGISGYGNLGRGVHQAIAQNPDMELVAIFTRRDPQQLQTPPGVHFEHISAADQYIG 62 + I+VGI GYGNLGRGV AI+QNPDMELVA+FTRRDP + + A+++ Sbjct: 2 SAIRVGIVGYGNLGRGVEYAISQNPDMELVAVFTRRDPSTVNVASNASVYVVEDAEKFQN 61 Query: 63 RIDVMILCGGSATDLPEQTPQLAAMFNTVDSFDTHAKIPEFFQSVNQAALGGGRLSVIST 122 IDVMILCGGSATDLPEQ P A FNT+DSFDTHAKIPEFF +V+ AA G++SVIS Sbjct: 62 DIDVMILCGGSATDLPEQGPHFAQWFNTIDSFDTHAKIPEFFDAVDGAAQKSGKVSVISV 121 Query: 123 GWDPGLFSMNRLLMEAVLPEGQEYTFWGPGVSQGHSDAIRRVPGVKAGVQYTVPVQAVID 182 GWDPGLFS+NRLL E+VLP G YTFWG G+SQGHSDA+RR+ GVK VQYT+P++ +D Sbjct: 122 GWDPGLFSLNRLLGESVLPVGTTYTFWGDGLSQGHSDAVRRIEGVKNAVQYTLPIKEAVD 181 Query: 183 GIRAGDTPKLETRQKHRRDCFVVAQEDADREQIRKAIVNMPNYFADYDTTVTFITQEQLA 242 +R G+ P+L TR+KH R+C+VV ++ AD ++ + IV MPNYF +Y+TTV FI++E+ Sbjct: 182 RVRNGENPELTTREKHARECWVVLEDGADAAKVEQEIVTMPNYFDEYNTTVNFISEEEFK 241 Query: 243 AEHSGMPHGGFVIRSGVSGNGSKQIAEFGLKLESNPEFTASVLVAYARAAFRLSQEGQRG 302 A H+GMPHGGFVIRSG SG KQI EF LKLESNP FT+SVLVAYARAA RL+Q G +G Sbjct: 242 ANHTGMPHGGFVIRSGDSGANDKQILEFSLKLESNPNFTSSVLVAYARAAHRLNQAGDKG 301 Query: 303 AKTVFDIPLGYLSPKSAEELRRGLL 327 AKTVFDIP LSPKSA ELR+ LL Sbjct: 302 AKTVFDIPFSLLSPKSAAELRKELL 326 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,960,348,292 Number of extensions: 80964132 Number of successful extensions: 190607 Number of sequences better than 1.0e-05: 119 Number of HSP's gapped: 190370 Number of HSP's successfully gapped: 122 Length of query: 327 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 191 Effective length of database: 1,779,438,163 Effective search space: 339872689133 Effective search space used: 339872689133 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)