BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0554.0010.p (462 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1ILQ5.1 B1ILQ5_CLOBK Dihydrolipoyl dehydrogenase EC=1.8.1.4 493 e-137 C3KW39.1 C3KW39_CLOB6 TPP-dependent acetoin dehydrogenase comple... 493 e-137 B1QQB2.1 B1QQB2_CLOBO Dihydrolipoyl dehydrogenase EC=1.8.1.4 493 e-137 A7GDW1.1 A7GDW1_CLOBL TPP-dependent acetoin dehydrogenase comple... 492 e-137 C1FNA0.1 C1FNA0_CLOBJ TPP-dependent acetoin dehydrogenase comple... 491 e-137 >B1ILQ5.1 B1ILQ5_CLOBK Dihydrolipoyl dehydrogenase EC=1.8.1.4 Length = 463 Score = 493 bits (1269), Expect = e-137, Method: Compositional matrix adjust. Identities = 250/461 (54%), Positives = 328/461 (71%), Gaps = 2/461 (0%) Query: 1 MRIVVLGGGPGGYVAAIRAAQLGAEVTLVEKKALGGTCLNVGCIPTKVLLHTTELYTHLK 60 M++VV+GGGPGGYVAAIR AQLGAEVTL+EK+ LGGTCLN+GCIPTKVLLH++EL +K Sbjct: 1 MKLVVIGGGPGGYVAAIRGAQLGAEVTLIEKEKLGGTCLNIGCIPTKVLLHSSELLNEIK 60 Query: 61 REGKALGIEAAD-VSVNWGQLQKRKDKIIRMNTGGIEALLTKNKVARLSGSGKFISAREL 119 E + LGIE + V +NW QLQ RK+ ++ G+ +LL NKV ++G+ F + Sbjct: 61 -EARTLGIEVNNEVKINWTQLQNRKNTVVNTLVSGVSSLLEHNKVKVINGTAAFEGKSSI 119 Query: 120 EVTAADGSVRTVGFDRAIIATGSEPSSVPIPGAGLEGVITSDGALSLPAVPPSLCIIGGG 179 +VT G + FD II++GS P PI G LEGVI S GALSL ++P S+ IIGGG Sbjct: 120 KVTKDQGESENIQFDNVIISSGSVPFIPPIEGRELEGVIDSTGALSLDSIPKSMVIIGGG 179 Query: 180 VIGCEFASVYSSLGCKVTVIEMLPELIAAMDGDIVQCLRKEFASSGIEVHTETKVERIEQ 239 VIG EFA++++SLGCKVTVIEMLP ++ +D +I + L+++ GI+++ KV +IE Sbjct: 180 VIGIEFANIFNSLGCKVTVIEMLPYILPPVDREISEILKEKLKKDGIDIYNNCKVTKIEN 239 Query: 240 TAAGLRVVTSSGNGSHVIEADKVLLSIGRRPVTAGLGLEDIGVQLTRGAIQVNRKMETCI 299 L V N IEA KVL+++GRR + L LE GV + +G I VN MET I Sbjct: 240 NNENLNVSFEEDNDKLNIEAQKVLIAVGRRANISNLNLESTGVYIEKGCIWVNDNMETNI 299 Query: 300 PGIYAIGDCNGGIMLAHVASAEGVIAAEAIMGEPSPVDFRTVPSCVYTRPELASVGMTET 359 GIYAIGDC G MLAHVAS +G+IA E IMG+ +D++TVP+CVYT+PELASVG+TE Sbjct: 300 KGIYAIGDCTGKNMLAHVASDQGIIAVENIMGKNKKMDYKTVPACVYTKPELASVGLTEE 359 Query: 360 EAKQQGFRVKTGLFPLQANAKSMIMGESSGLVKYVVDAGNDEILGLHIAGPRATDIIVEG 419 +AKQ+G K G FPL N KS+IM ++ G +K +VD +EILG+HI GPRATD+I E Sbjct: 360 QAKQKGVDYKVGKFPLIYNGKSLIMNDTEGFIKIIVDKKYEEILGVHILGPRATDLITEA 419 Query: 420 ALAIRLEATLEEVVTTIHAHPTVAESLHEAAHAVHGRAIHL 460 ALA+RLEATLEE++TT+HAHPT+ E++ EAA AV+ AIH+ Sbjct: 420 ALALRLEATLEEIITTVHAHPTIGEAMKEAALAVNKEAIHM 460 >C3KW39.1 C3KW39_CLOB6 TPP-dependent acetoin dehydrogenase complex, E3 component, dihydrolipoyl dehydrogenase EC=1.8.1.4 Length = 463 Score = 493 bits (1268), Expect = e-137, Method: Compositional matrix adjust. Identities = 254/461 (55%), Positives = 332/461 (72%), Gaps = 2/461 (0%) Query: 1 MRIVVLGGGPGGYVAAIRAAQLGAEVTLVEKKALGGTCLNVGCIPTKVLLHTTELYTHLK 60 M++VV+GGGPGGYVAAIR AQLGAEVTL+EK+ LGGTCLNVGCIPTKVLLH++EL +K Sbjct: 1 MKLVVIGGGPGGYVAAIRGAQLGAEVTLIEKEKLGGTCLNVGCIPTKVLLHSSELLNEIK 60 Query: 61 REGKALGIEAAD-VSVNWGQLQKRKDKIIRMNTGGIEALLTKNKVARLSGSGKFISAREL 119 E K LGIE + V VNW QLQ RK+ ++ G+ +LL NKV ++G+ F + Sbjct: 61 -EAKILGIEVNNEVKVNWTQLQNRKNTVVNTLVSGVSSLLEHNKVKVINGTATFEGKSSI 119 Query: 120 EVTAADGSVRTVGFDRAIIATGSEPSSVPIPGAGLEGVITSDGALSLPAVPPSLCIIGGG 179 +VT G + FD AII++GS P PI G LEGVI S GAL L +VP S+ IIGGG Sbjct: 120 KVTKDKGESENIQFDNAIISSGSIPFIPPIEGKELEGVIDSTGALGLDSVPKSMVIIGGG 179 Query: 180 VIGCEFASVYSSLGCKVTVIEMLPELIAAMDGDIVQCLRKEFASSGIEVHTETKVERIEQ 239 VIG EFA++++SLGC+VTVIEMLP ++ +D +I + L+++ + GI+++ KV +I++ Sbjct: 180 VIGIEFANIFNSLGCEVTVIEMLPYILPPVDREISEILKEKLKNDGIDIYNNCKVTKIKK 239 Query: 240 TAAGLRVVTSSGNGSHVIEADKVLLSIGRRPVTAGLGLEDIGVQLTRGAIQVNRKMETCI 299 L V GN IEA KVL+++GRR T L LE IGV +G I VN MET I Sbjct: 240 NDENLNVSFEKGNDKLNIEAQKVLIAVGRRANTGNLNLESIGVSTEKGCILVNDNMETNI 299 Query: 300 PGIYAIGDCNGGIMLAHVASAEGVIAAEAIMGEPSPVDFRTVPSCVYTRPELASVGMTET 359 GIYAIGDC G MLAHVAS +G+IA E IMG+ +D++TVP+CVYT+PELASVG+TE Sbjct: 300 KGIYAIGDCIGKNMLAHVASDQGIIAVENIMGKNKKMDYKTVPACVYTKPELASVGLTEE 359 Query: 360 EAKQQGFRVKTGLFPLQANAKSMIMGESSGLVKYVVDAGNDEILGLHIAGPRATDIIVEG 419 +AKQ+G K G FPL N KS+IMG++ G++K + D +E+LG+HI GPRATD+I E Sbjct: 360 QAKQKGVDYKVGKFPLIYNGKSLIMGDTGGVIKIIADKKYEEVLGVHILGPRATDLIAEA 419 Query: 420 ALAIRLEATLEEVVTTIHAHPTVAESLHEAAHAVHGRAIHL 460 ALA+RLEATLEE++TT+HAHPT+ E++ EAA AV+ AIH+ Sbjct: 420 ALALRLEATLEEIITTVHAHPTIGEAMKEAALAVNKEAIHM 460 >B1QQB2.1 B1QQB2_CLOBO Dihydrolipoyl dehydrogenase EC=1.8.1.4 Length = 463 Score = 493 bits (1268), Expect = e-137, Method: Compositional matrix adjust. Identities = 254/461 (55%), Positives = 332/461 (72%), Gaps = 2/461 (0%) Query: 1 MRIVVLGGGPGGYVAAIRAAQLGAEVTLVEKKALGGTCLNVGCIPTKVLLHTTELYTHLK 60 M++VV+GGGPGGYVAAIR AQLGAEVTL+EK+ LGGTCLNVGCIPTKVLLH++EL +K Sbjct: 1 MKLVVIGGGPGGYVAAIRGAQLGAEVTLIEKEKLGGTCLNVGCIPTKVLLHSSELLNEIK 60 Query: 61 REGKALGIEAAD-VSVNWGQLQKRKDKIIRMNTGGIEALLTKNKVARLSGSGKFISAREL 119 E K LGIE + V VNW QLQ RK+ ++ G+ +LL NKV ++G+ F + Sbjct: 61 -EAKILGIEVNNEVKVNWTQLQNRKNTVVNTLVSGVSSLLEHNKVKVINGTATFEGKSSI 119 Query: 120 EVTAADGSVRTVGFDRAIIATGSEPSSVPIPGAGLEGVITSDGALSLPAVPPSLCIIGGG 179 +VT G + FD AII++GS P PI G LEGVI S GAL L +VP S+ IIGGG Sbjct: 120 KVTKDKGESENIQFDNAIISSGSIPFIPPIEGKELEGVIDSTGALGLDSVPKSMVIIGGG 179 Query: 180 VIGCEFASVYSSLGCKVTVIEMLPELIAAMDGDIVQCLRKEFASSGIEVHTETKVERIEQ 239 VIG EFA++++SLGC+VTVIEMLP ++ +D +I + L+++ + GI+++ KV +I++ Sbjct: 180 VIGIEFANIFNSLGCEVTVIEMLPYILPPVDREISEILKEKLKNDGIDIYNNCKVTKIKK 239 Query: 240 TAAGLRVVTSSGNGSHVIEADKVLLSIGRRPVTAGLGLEDIGVQLTRGAIQVNRKMETCI 299 L V GN IEA KVL+++GRR T L LE IGV +G I VN MET I Sbjct: 240 NDENLNVSFEKGNDKLNIEAQKVLIAVGRRANTGNLNLESIGVSTEKGCILVNDNMETNI 299 Query: 300 PGIYAIGDCNGGIMLAHVASAEGVIAAEAIMGEPSPVDFRTVPSCVYTRPELASVGMTET 359 GIYAIGDC G MLAHVAS +G+IA E IMG+ +D++TVP+CVYT+PELASVG+TE Sbjct: 300 KGIYAIGDCIGKNMLAHVASDQGIIAVENIMGKNKKMDYKTVPACVYTKPELASVGLTEE 359 Query: 360 EAKQQGFRVKTGLFPLQANAKSMIMGESSGLVKYVVDAGNDEILGLHIAGPRATDIIVEG 419 +AKQ+G K G FPL N KS+IMG++ G++K + D +E+LG+HI GPRATD+I E Sbjct: 360 QAKQKGVDYKVGKFPLIYNGKSLIMGDTGGVIKIIADKKYEEVLGVHILGPRATDLIAEA 419 Query: 420 ALAIRLEATLEEVVTTIHAHPTVAESLHEAAHAVHGRAIHL 460 ALA+RLEATLEE++TT+HAHPT+ E++ EAA AV+ AIH+ Sbjct: 420 ALALRLEATLEEIITTVHAHPTIGEAMKEAALAVNKEAIHM 460 >A7GDW1.1 A7GDW1_CLOBL TPP-dependent acetoin dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase EC=1.8.1.4 Length = 463 Score = 492 bits (1266), Expect = e-137, Method: Compositional matrix adjust. Identities = 250/461 (54%), Positives = 327/461 (70%), Gaps = 2/461 (0%) Query: 1 MRIVVLGGGPGGYVAAIRAAQLGAEVTLVEKKALGGTCLNVGCIPTKVLLHTTELYTHLK 60 M++VV+GGGPGGYVAAIR AQLGAEVTL+EK+ LGGTCLN+GCIPTKVLLH++EL +K Sbjct: 1 MKLVVIGGGPGGYVAAIRGAQLGAEVTLIEKEKLGGTCLNIGCIPTKVLLHSSELLNEIK 60 Query: 61 REGKALGIEAAD-VSVNWGQLQKRKDKIIRMNTGGIEALLTKNKVARLSGSGKFISAREL 119 E + LGIE + V +NW QLQ RK+ ++ G+ +LL NKV ++G+ F + Sbjct: 61 -EARTLGIEVNNEVKINWTQLQNRKNTVVNTLVSGVSSLLEHNKVKVINGTAAFEGKSSI 119 Query: 120 EVTAADGSVRTVGFDRAIIATGSEPSSVPIPGAGLEGVITSDGALSLPAVPPSLCIIGGG 179 +VT G + FD II++GS P PI G LEGVI S GALSL ++P S+ IIGGG Sbjct: 120 KVTKDQGESENIQFDNVIISSGSVPFIPPIEGRELEGVIDSTGALSLDSIPKSMVIIGGG 179 Query: 180 VIGCEFASVYSSLGCKVTVIEMLPELIAAMDGDIVQCLRKEFASSGIEVHTETKVERIEQ 239 VIG EFA++++SLGCKVTVIEMLP ++ +D +I + L+++ GI+++ KV +IE Sbjct: 180 VIGIEFANIFNSLGCKVTVIEMLPYILPPVDREISEILKEKLKKDGIDIYNNCKVTKIEN 239 Query: 240 TAAGLRVVTSSGNGSHVIEADKVLLSIGRRPVTAGLGLEDIGVQLTRGAIQVNRKMETCI 299 L V N IEA KVL+++GRR L LE GV + +G I VN MET I Sbjct: 240 NNENLNVSFEEDNDKLNIEAQKVLIAVGRRANIGNLNLESTGVYIEKGCIWVNDNMETNI 299 Query: 300 PGIYAIGDCNGGIMLAHVASAEGVIAAEAIMGEPSPVDFRTVPSCVYTRPELASVGMTET 359 GIYAIGDC G MLAHVAS +G+IA E IMG+ +D++TVP+CVYT+PELASVG+TE Sbjct: 300 KGIYAIGDCTGKNMLAHVASDQGIIAVENIMGKNKKMDYKTVPACVYTKPELASVGLTEE 359 Query: 360 EAKQQGFRVKTGLFPLQANAKSMIMGESSGLVKYVVDAGNDEILGLHIAGPRATDIIVEG 419 +AKQ+G K G FPL N KS+IM ++ G +K +VD +EILG+HI GPRATD+I E Sbjct: 360 QAKQKGVDYKVGKFPLIYNGKSLIMNDTEGFIKIIVDKKYEEILGVHILGPRATDLITEA 419 Query: 420 ALAIRLEATLEEVVTTIHAHPTVAESLHEAAHAVHGRAIHL 460 ALA+RLEATLEE++TT+HAHPT+ E++ EAA AV+ AIH+ Sbjct: 420 ALALRLEATLEEIITTVHAHPTIGEAMKEAALAVNKEAIHM 460 >C1FNA0.1 C1FNA0_CLOBJ TPP-dependent acetoin dehydrogenase complex, E3 component, dihydrolipoyl dehydrogenase EC=1.8.1.4 Length = 463 Score = 491 bits (1263), Expect = e-137, Method: Compositional matrix adjust. Identities = 249/461 (54%), Positives = 327/461 (70%), Gaps = 2/461 (0%) Query: 1 MRIVVLGGGPGGYVAAIRAAQLGAEVTLVEKKALGGTCLNVGCIPTKVLLHTTELYTHLK 60 M++VV+GGGPGGYVAAIR AQLGAEVTL+EK+ LGGTCLN+GCIPTKVLLH++EL +K Sbjct: 1 MKLVVIGGGPGGYVAAIRGAQLGAEVTLIEKEKLGGTCLNIGCIPTKVLLHSSELLNEIK 60 Query: 61 REGKALGIEAAD-VSVNWGQLQKRKDKIIRMNTGGIEALLTKNKVARLSGSGKFISAREL 119 E + LGIE + V +NW QLQ RK+ ++ G+ +LL NKV ++G+ F + Sbjct: 61 -EARTLGIEVNNEVKINWTQLQNRKNTVVNTLVSGVSSLLEHNKVKVINGTAAFEGKSSI 119 Query: 120 EVTAADGSVRTVGFDRAIIATGSEPSSVPIPGAGLEGVITSDGALSLPAVPPSLCIIGGG 179 +VT G + FD II++GS P PI G LEGVI S GALSL ++P S+ IIGGG Sbjct: 120 KVTKDQGESENIQFDNVIISSGSVPFIPPIKGRELEGVIDSTGALSLDSIPKSMVIIGGG 179 Query: 180 VIGCEFASVYSSLGCKVTVIEMLPELIAAMDGDIVQCLRKEFASSGIEVHTETKVERIEQ 239 VIG EFA++++SLGCKVTVIEMLP ++ +D +I + L+++ GI+++ KV +IE Sbjct: 180 VIGIEFANIFNSLGCKVTVIEMLPYILPPVDREISEILKEKLKKDGIDIYNNCKVTKIEN 239 Query: 240 TAAGLRVVTSSGNGSHVIEADKVLLSIGRRPVTAGLGLEDIGVQLTRGAIQVNRKMETCI 299 L V N IEA KVL+++GRR + L LE GV + +G I VN MET I Sbjct: 240 NNENLNVSFEEDNDKLNIEAQKVLIAVGRRANISNLNLESTGVYIEKGCIWVNDNMETNI 299 Query: 300 PGIYAIGDCNGGIMLAHVASAEGVIAAEAIMGEPSPVDFRTVPSCVYTRPELASVGMTET 359 GIYAIGDC G MLAHVAS +G+IA E IMG+ +D++TVP+CVYT+PELASVG+TE Sbjct: 300 KGIYAIGDCTGKNMLAHVASDQGIIAVENIMGKNKKMDYKTVPACVYTKPELASVGLTEE 359 Query: 360 EAKQQGFRVKTGLFPLQANAKSMIMGESSGLVKYVVDAGNDEILGLHIAGPRATDIIVEG 419 +AKQ+G K G FPL N KS+IM ++ G +K + D +EILG+HI GPRATD+I E Sbjct: 360 QAKQKGVDYKIGKFPLIYNGKSLIMNDTEGFIKIIADKKYEEILGVHILGPRATDLITEA 419 Query: 420 ALAIRLEATLEEVVTTIHAHPTVAESLHEAAHAVHGRAIHL 460 ALA+RLEATLEE++TT+HAHPT+ E++ EAA AV+ AIH+ Sbjct: 420 ALALRLEATLEEIITTVHAHPTIGEAMKEAALAVNKEAIHM 460 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.135 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,657,394,682 Number of extensions: 112013685 Number of successful extensions: 442598 Number of sequences better than 1.0e-05: 8773 Number of HSP's gapped: 412491 Number of HSP's successfully gapped: 8815 Length of query: 462 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 323 Effective length of database: 1,751,175,118 Effective search space: 565629563114 Effective search space used: 565629563114 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)