BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0551.0005.p (409 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0ZEY4.1 C0ZEY4_BREBN Putative drug resistance transporter 352 4e-95 Q81IY9.1 Q81IY9_BACCR Bicyclomycin resistance protein 327 2e-87 Q3F0U2.1 Q3F0U2_BACTI Multidrug resistance transporter, Bcr family 326 2e-87 B7HJL8.1 B7HJL8_BACC4 Drug resistance transporter, Bcr/CflA family 325 3e-87 C1EU34.1 C1EU34_BACC3 Drug resistance transporter, Bcr/CflA family 325 5e-87 >C0ZEY4.1 C0ZEY4_BREBN Putative drug resistance transporter Length = 410 Score = 352 bits (903), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 188/393 (47%), Positives = 252/393 (64%) Query: 16 SRKQRLQIAVILGAISAIGPLSIDMYXXXXXXXXXXXXXXXXXVQLSLTFFLLGLASGQL 75 ++ +RL +A ILG++SA GPLS+DMY QLSLT +LGL+ GQL Sbjct: 16 NKSRRLWMAAILGSLSAFGPLSLDMYLPALPMLADDLQTSTSMTQLSLTACMLGLSIGQL 75 Query: 76 VAGPLSDVYGRRTPLLIGMLVYAVSSLLCAFTPSIGLLVMLRFIQGLAGSVGVVISRAAV 135 AGP+SDV GRR PL+IG+++YAVSS LCA PSI V+LRF+QGLAGS G+VI+RA V Sbjct: 76 FAGPISDVRGRRIPLIIGLILYAVSSFLCAVAPSIYTFVLLRFVQGLAGSAGIVIARATV 135 Query: 136 RDLYSGSELTKFFSLLMIVNGLGPILAPVIGGQLLRVTTWQGVFMVLFAAGLIFFVTILL 195 RDLY+G+ELTKFF+LLM++NG+ PI AP++GGQ+L TTW GVF+VL G I F+ +LL Sbjct: 136 RDLYAGTELTKFFALLMLINGIAPIAAPIVGGQILEFTTWHGVFVVLGLIGAIMFLVVLL 195 Query: 196 RLPETLPKERRLKSGIRGTLRTFAVLLGNGRFMGYALSQGFVSAAMFAYISGSSFVLQNI 255 LPETLP++RR K+GI TL TF LL + FMGYA++QG V+AAMFAYI+GS FV Q I Sbjct: 196 ALPETLPQDRRSKAGIGNTLATFGTLLKDRVFMGYAVTQGLVTAAMFAYIAGSPFVFQKI 255 Query: 256 FGVSPQMYSVIFAVNGLGIILSGQIAGRLAGRIGEQKFXXXXXXXXXXXXXXXXXXXXXX 315 F VSPQ +S+IFA+NG+GII++ QI G+LAG++ E Sbjct: 256 FEVSPQTFSLIFAINGVGIIIASQITGKLAGKVKETSLFIAGITIAGVGGILLLAMILLQ 315 Query: 316 XXXXPILLCLFAXXXXXXXXXXXXFSLAMQDQGDXXXXXXXXXXXXXXXXXXCVAPLVGL 375 +L+ LF FSLAMQ+Q VAPLVG+ Sbjct: 316 AGLIAVLVPLFFVVSSVGIVGATGFSLAMQNQSKAAGSASALQGLLSFISGGIVAPLVGI 375 Query: 376 GGSETALPMAMVIAGAGVCSILSFLLLCRQGSA 408 G TA+PM ++IA + + +I+ ++++ R+ S+ Sbjct: 376 SGEHTAVPMGIIIALSTIGAIVCYVVMVRRSSS 408 >Q81IY9.1 Q81IY9_BACCR Bicyclomycin resistance protein Length = 416 Score = 327 bits (837), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 189/395 (47%), Positives = 243/395 (61%) Query: 15 PSRKQRLQIAVILGAISAIGPLSIDMYXXXXXXXXXXXXXXXXXVQLSLTFFLLGLASGQ 74 P + RL + ++LG ++AIGPLSIDMY QL+LT LLGL+ GQ Sbjct: 11 PVKANRLWMILVLGTLTAIGPLSIDMYLPSLPKLTDDLQTGASLAQLTLTACLLGLSVGQ 70 Query: 75 LVAGPLSDVYGRRTPLLIGMLVYAVSSLLCAFTPSIGLLVMLRFIQGLAGSVGVVISRAA 134 L G +SD+YGRR PL+I +++Y SSLLCA PSI LV+LRF+QG +GS G+VISRA Sbjct: 71 LFVGSISDIYGRRKPLIIALIIYVASSLLCAVAPSIWTLVLLRFLQGASGSAGIVISRAM 130 Query: 135 VRDLYSGSELTKFFSLLMIVNGLGPILAPVIGGQLLRVTTWQGVFMVLFAAGLIFFVTIL 194 VRD+YSGSE+TKFFSLLM+VNG PILAP+IGGQLL+ TTW+GVF+VL A + ++ Sbjct: 131 VRDMYSGSEMTKFFSLLMLVNGAAPILAPIIGGQLLQFTTWRGVFIVLGAISVFMLISAT 190 Query: 195 LRLPETLPKERRLKSGIRGTLRTFAVLLGNGRFMGYALSQGFVSAAMFAYISGSSFVLQN 254 L ETLP E R G+ GTL T+ LL + FMGYALSQG V+AAMFAYISGS FVLQN Sbjct: 191 FVLRETLPPEERETGGLSGTLATYGKLLKDRLFMGYALSQGLVTAAMFAYISGSPFVLQN 250 Query: 255 IFGVSPQMYSVIFAVNGLGIILSGQIAGRLAGRIGEQKFXXXXXXXXXXXXXXXXXXXXX 314 I+G SPQ +S+ FA+NG+GII++ Q+ GRLAG++ E+ Sbjct: 251 IYGASPQQFSLFFAINGIGIIIASQVTGRLAGKVNEKTLFVAGIIIAAVGGLSLLLTIVL 310 Query: 315 XXXXXPILLCLFAXXXXXXXXXXXXFSLAMQDQGDXXXXXXXXXXXXXXXXXXCVAPLVG 374 +L LF FSLAM++Q VAPLVG Sbjct: 311 GIGLIGVLCSLFLVVSSVGVVSTTGFSLAMRNQKQAAGTASALLGLLQFISGALVAPLVG 370 Query: 375 LGGSETALPMAMVIAGAGVCSILSFLLLCRQGSAK 409 +GGS TALPM +VIA V ++L +L + R+ + Sbjct: 371 IGGSNTALPMGVVIALCEVGAVLCYLFMARRSEKQ 405 >Q3F0U2.1 Q3F0U2_BACTI Multidrug resistance transporter, Bcr family Length = 416 Score = 326 bits (836), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 189/395 (47%), Positives = 243/395 (61%) Query: 15 PSRKQRLQIAVILGAISAIGPLSIDMYXXXXXXXXXXXXXXXXXVQLSLTFFLLGLASGQ 74 P + RL + ++LG ++AIGPLSIDMY QL+LT LLGL+ GQ Sbjct: 11 PVKANRLWMILVLGTLTAIGPLSIDMYLPSLPKLTDDLQTGASLAQLTLTACLLGLSVGQ 70 Query: 75 LVAGPLSDVYGRRTPLLIGMLVYAVSSLLCAFTPSIGLLVMLRFIQGLAGSVGVVISRAA 134 L G +SD+YGRR PL+I +++Y SSLLCA PSI LV+LRF+QG +GS G+VISRA Sbjct: 71 LFVGSISDIYGRRKPLIIALIIYVASSLLCAVAPSIWTLVLLRFLQGASGSAGIVISRAM 130 Query: 135 VRDLYSGSELTKFFSLLMIVNGLGPILAPVIGGQLLRVTTWQGVFMVLFAAGLIFFVTIL 194 VRD+YSGSE+TKFFSLLM+VNG PILAP+IGGQLL+ TTW+GVF+VL A + ++ Sbjct: 131 VRDMYSGSEMTKFFSLLMLVNGAAPILAPIIGGQLLQFTTWRGVFIVLGAISVFMLISAT 190 Query: 195 LRLPETLPKERRLKSGIRGTLRTFAVLLGNGRFMGYALSQGFVSAAMFAYISGSSFVLQN 254 L ETLP E R G+ GTL T+ LL + FMGYALSQG V+AAMFAYISGS FVLQN Sbjct: 191 FVLRETLPPEERETGGLSGTLATYGKLLKDRLFMGYALSQGLVTAAMFAYISGSPFVLQN 250 Query: 255 IFGVSPQMYSVIFAVNGLGIILSGQIAGRLAGRIGEQKFXXXXXXXXXXXXXXXXXXXXX 314 I+G SPQ +S+ FA+NG+GII++ Q+ GRLAG++ E+ Sbjct: 251 IYGASPQQFSLFFAINGIGIIIASQVTGRLAGKVNEKTLFVAGIIIAAVGGLSLLLTIVL 310 Query: 315 XXXXXPILLCLFAXXXXXXXXXXXXFSLAMQDQGDXXXXXXXXXXXXXXXXXXCVAPLVG 374 +L LF FSLAM++Q VAPLVG Sbjct: 311 GIGLIGVLCSLFLVVSSVGVVSTTGFSLAMRNQKQAAGTASALLGLLQFISGALVAPLVG 370 Query: 375 LGGSETALPMAMVIAGAGVCSILSFLLLCRQGSAK 409 +GGS TALPM +VIA V ++L +L + R+ + Sbjct: 371 IGGSNTALPMGVVIALCEVGAVLCYLFMARRSEKQ 405 >B7HJL8.1 B7HJL8_BACC4 Drug resistance transporter, Bcr/CflA family Length = 416 Score = 325 bits (834), Expect = 3e-87, Method: Compositional matrix adjust. Identities = 189/395 (47%), Positives = 244/395 (61%) Query: 15 PSRKQRLQIAVILGAISAIGPLSIDMYXXXXXXXXXXXXXXXXXVQLSLTFFLLGLASGQ 74 P + RL + ++LG ++AIGPLSIDMY QL+LT LLGL+ GQ Sbjct: 11 PVKANRLWMILVLGTLTAIGPLSIDMYLPSLPKLTDDLQTGASLAQLTLTACLLGLSVGQ 70 Query: 75 LVAGPLSDVYGRRTPLLIGMLVYAVSSLLCAFTPSIGLLVMLRFIQGLAGSVGVVISRAA 134 L G +SD+YGRR PL+I +++Y SSLLCA PSI LV+LRF+QG +GS G+VISRA Sbjct: 71 LFVGSISDIYGRRKPLIIALIIYVASSLLCAVAPSIWTLVLLRFLQGASGSAGIVISRAM 130 Query: 135 VRDLYSGSELTKFFSLLMIVNGLGPILAPVIGGQLLRVTTWQGVFMVLFAAGLIFFVTIL 194 VRD+YSGSE+TKFFSLLM+VNG PILAP+IGGQLL+ TTW+GVF+VL A + ++ + Sbjct: 131 VRDMYSGSEMTKFFSLLMLVNGAAPILAPIIGGQLLQFTTWRGVFIVLGAISVFMLISAI 190 Query: 195 LRLPETLPKERRLKSGIRGTLRTFAVLLGNGRFMGYALSQGFVSAAMFAYISGSSFVLQN 254 L ETLP E R G+ GTL T+ LL + FMGYALSQG V+AAMFAYISGS FVLQN Sbjct: 191 FVLRETLPPEERETGGLSGTLATYGKLLKDRLFMGYALSQGLVTAAMFAYISGSPFVLQN 250 Query: 255 IFGVSPQMYSVIFAVNGLGIILSGQIAGRLAGRIGEQKFXXXXXXXXXXXXXXXXXXXXX 314 I+G SPQ +S+ FA+NG+GII++ Q+ GRLAG++ E+ Sbjct: 251 IYGASPQQFSLFFAINGIGIIIASQVTGRLAGKVNEKTLFVSGIIIAAVGGLSLLLTILL 310 Query: 315 XXXXXPILLCLFAXXXXXXXXXXXXFSLAMQDQGDXXXXXXXXXXXXXXXXXXCVAPLVG 374 +L LF FSLAM++Q VAPLVG Sbjct: 311 GIGLIGVLCSLFLVVSSVGVVSTTGFSLAMRNQKQAAGTASALLGLLQFISGALVAPLVG 370 Query: 375 LGGSETALPMAMVIAGAGVCSILSFLLLCRQGSAK 409 +GGS TALPM +VIA V ++L +L + R+ + Sbjct: 371 IGGSNTALPMGVVIALCEVGAVLCYLFMARRSEKQ 405 >C1EU34.1 C1EU34_BACC3 Drug resistance transporter, Bcr/CflA family Length = 419 Score = 325 bits (833), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 188/395 (47%), Positives = 243/395 (61%) Query: 15 PSRKQRLQIAVILGAISAIGPLSIDMYXXXXXXXXXXXXXXXXXVQLSLTFFLLGLASGQ 74 P + RL + ++LG ++AIGPLSIDMY QL+LT LLGL+ GQ Sbjct: 14 PVKTNRLWMILVLGTLTAIGPLSIDMYLPSLPKLTDDLQTGASLAQLTLTACLLGLSVGQ 73 Query: 75 LVAGPLSDVYGRRTPLLIGMLVYAVSSLLCAFTPSIGLLVMLRFIQGLAGSVGVVISRAA 134 L G +SD+YGRR PL+I +++Y SSLLCA PSI LV+LRF+QG +GS G+VISRA Sbjct: 74 LFVGSISDIYGRRKPLIIALIIYVASSLLCAVAPSIWTLVLLRFLQGASGSAGIVISRAM 133 Query: 135 VRDLYSGSELTKFFSLLMIVNGLGPILAPVIGGQLLRVTTWQGVFMVLFAAGLIFFVTIL 194 VRD+YSGSE+TKFFSLLM+VNG PILAP+IGGQLL+ TTW+GVF+VL A + ++ Sbjct: 134 VRDMYSGSEMTKFFSLLMLVNGAAPILAPIIGGQLLQFTTWRGVFIVLGAISVFMLISAT 193 Query: 195 LRLPETLPKERRLKSGIRGTLRTFAVLLGNGRFMGYALSQGFVSAAMFAYISGSSFVLQN 254 L ETLP E R G+ GTL T+ LL + FMGYALSQG V+AAMFAYISGS FVLQN Sbjct: 194 FVLRETLPPEERETGGLSGTLATYGKLLKDRLFMGYALSQGLVTAAMFAYISGSPFVLQN 253 Query: 255 IFGVSPQMYSVIFAVNGLGIILSGQIAGRLAGRIGEQKFXXXXXXXXXXXXXXXXXXXXX 314 I+G SPQ +S+ FA+NG+GII++ Q+ GRLAG++ E+ Sbjct: 254 IYGASPQQFSLFFAINGIGIIIASQVTGRLAGKVNEKTLFVSGIVIAAVGGLSLLLTILL 313 Query: 315 XXXXXPILLCLFAXXXXXXXXXXXXFSLAMQDQGDXXXXXXXXXXXXXXXXXXCVAPLVG 374 +L LF FSLAM++Q VAPLVG Sbjct: 314 GIGLIGVLCSLFLVVSSVGVVSTTGFSLAMRNQKQAAGTASALLGLLQFISGALVAPLVG 373 Query: 375 LGGSETALPMAMVIAGAGVCSILSFLLLCRQGSAK 409 +GGS TALPM +VIA + ++L +L + R+ + Sbjct: 374 IGGSNTALPMGVVIALCEIGAVLCYLFMARRSEKQ 408 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.328 0.144 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,767,153,987 Number of extensions: 63909934 Number of successful extensions: 300808 Number of sequences better than 1.0e-05: 10790 Number of HSP's gapped: 299543 Number of HSP's successfully gapped: 10790 Length of query: 409 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 271 Effective length of database: 1,760,596,133 Effective search space: 477121552043 Effective search space used: 477121552043 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 132 (55.5 bits)