BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0547.0052.p (491 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DHT2.1 B1DHT2_9BACL Orn/Lys/Arg decarboxylase major region 753 0.0 B7GGH7.1 B7GGH7_ANOFW Arginine decarboxylase 656 0.0 Q2B4X4.1 Q2B4X4_9BACI Lysine decarboxylase (LDC) 650 0.0 A6CTA6.1 A6CTA6_9BACI Lysine decarboxylase (LDC) 649 0.0 A8FCS7.1 A8FCS7_BACP2 Lysine decarboxylase EC=4.1.1.18 647 0.0 >B1DHT2.1 B1DHT2_9BACL Orn/Lys/Arg decarboxylase major region Length = 489 Score = 753 bits (1945), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/490 (72%), Positives = 415/490 (84%), Gaps = 2/490 (0%) Query: 1 MDQHVTPLFTALKKHAAGNPVQFHIPGHKKGLGTDAEFREFIGDNALSIDLINIAPLDDL 60 MD + TPLF+AL++HA +PVQFHIPGHKKGLG+D EFREFIGDNALSIDLINIAPLDDL Sbjct: 1 MDHNNTPLFSALRRHADNDPVQFHIPGHKKGLGSDTEFREFIGDNALSIDLINIAPLDDL 60 Query: 61 HQPTGVILEAQKLAAEAFGADYTYFSVQGTSNAIMTMILSVCSEGDKIIVPRNIHKSVMS 120 HQPTGVI EAQKLAA+AFGADYTYFSVQGTS AI+TMIL+VCS GDKIIVPRNIHKSVM+ Sbjct: 61 HQPTGVIEEAQKLAADAFGADYTYFSVQGTSGAIITMILTVCSPGDKIIVPRNIHKSVMA 120 Query: 121 AIIFSGAKPVFVSPVQDENLGIDHGITTSALEKALRRHPDAKGVLVINPTYFGVCADLRS 180 AIIF+GA+PVF+SP +D NLGIDHGITT ++++AL RHPDAK VLVINPTYFG+CA+L+ Sbjct: 121 AIIFAGARPVFISPARDSNLGIDHGITTRSVKRALDRHPDAKAVLVINPTYFGICANLKE 180 Query: 181 IVDLAHSYGVPVLVDEAHGVLIHFHEDLPVSAMQAGADLAATSVHKLGGSMTQSSVLNLN 240 IVDL HSY +PVLVDEAHGVLIHFHE LP+SAMQAGAD+AATSVHKLGGSMTQSSVLN+ Sbjct: 181 IVDLVHSYDIPVLVDEAHGVLIHFHEKLPMSAMQAGADMAATSVHKLGGSMTQSSVLNV- 239 Query: 241 AKTGLVNPQRVQXXXXXXXXXXXXXXXXXXXDTSRRNLALNGHEMAARTIALSNYARDAI 300 + G +NP R+Q DTSRRNLA+NGHE+A R I L+ AR+ I Sbjct: 240 -RKGRINPFRIQTILSMLTTTSTSYILLASLDTSRRNLAINGHEIAERAIELAQSAREQI 298 Query: 301 NNIDGLYSFGKEILGTEATFNIDPTKLNIHVRHLGITGYETENWLREKYKIEVELSDMYN 360 N I GLY FG++ILG EAT++ DPTK+ +HVRHLG+TGYE ENWLR+ Y +E+E+SDMYN Sbjct: 299 NQIPGLYCFGEDILGDEATYDYDPTKVTVHVRHLGVTGYEVENWLRDNYNVEIEMSDMYN 358 Query: 361 ILCLITPGDTQESVDKLISALRVLSAVHYSKGEIYELKVQVPEIPQLALIPRDAFYADTQ 420 ILCL+TPGDT ES+DKL+ ALR LS ++ E EL V++P+IPQL+L PRDAFY +T+ Sbjct: 359 ILCLVTPGDTSESIDKLLQALRGLSETYHEGAEARELVVKIPDIPQLSLTPRDAFYGETE 418 Query: 421 VVPFRESAGYIIAEFIYVYPPGIPILLPGEVITQDNIDYIIDHVEIGLPVKGPEDRSINY 480 +VPF+ESAG IIAEFIYVYPPGIPILLPGEVI+Q NIDYI+DHVE+GLPVKGPEDRSI + Sbjct: 419 IVPFKESAGRIIAEFIYVYPPGIPILLPGEVISQKNIDYIVDHVEVGLPVKGPEDRSIQF 478 Query: 481 VKVIVEAEPI 490 VKVIVE I Sbjct: 479 VKVIVEENAI 488 >B7GGH7.1 B7GGH7_ANOFW Arginine decarboxylase Length = 488 Score = 656 bits (1693), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/487 (64%), Positives = 385/487 (79%), Gaps = 3/487 (0%) Query: 1 MDQHVTPLFTALKKHAAGNPVQFHIPGHKKGLGTDAEFREFIGDNALSIDLINIAPLDDL 60 M Q+ TPLFT L +H NP+QFHIPGHKKG G D +FR FIG+NAL+IDLINI PLDDL Sbjct: 1 MSQYETPLFTGLLEHIKKNPIQFHIPGHKKGAGMDEQFRSFIGENALAIDLINIGPLDDL 60 Query: 61 HQPTGVILEAQKLAAEAFGADYTYFSVQGTSNAIMTMILSVCSEGDKIIVPRNIHKSVMS 120 HQP G+I AQ+LAAEAFGADYT+FSVQGTS AIMTM++SV GDKIIVPRN+HKSVMS Sbjct: 61 HQPKGMIKRAQELAAEAFGADYTFFSVQGTSGAIMTMVMSVAGPGDKIIVPRNVHKSVMS 120 Query: 121 AIIFSGAKPVFVSPVQDENLGIDHGITTSALEKALRRHPDAKGVLVINPTYFGVCADLRS 180 AI+FSGA P+FV P D+ LGI HGIT A+E AL++HPDAKGVLVINPTYFG+ DL+ Sbjct: 121 AIVFSGATPIFVHPEIDKELGISHGITPEAVEAALKQHPDAKGVLVINPTYFGIAGDLKR 180 Query: 181 IVDLAHSYGVPVLVDEAHGVLIHFHEDLPVSAMQAGADLAATSVHKLGGSMTQSSVLNLN 240 IVD+AH+YGVPVLVDEAHGV IHFHE+LP+SAMQAGAD+AATSVHKLGGSMTQSS+LN+ Sbjct: 181 IVDIAHAYGVPVLVDEAHGVHIHFHEELPLSAMQAGADMAATSVHKLGGSMTQSSILNV- 239 Query: 241 AKTGLVNPQRVQXXXXXXXXXXXXXXXXXXXDTSRRNLALNGHEMAARTIALSNYARDAI 300 K GLV+P+RVQ D +R+ LA GHE+A + I L+N R I Sbjct: 240 -KEGLVSPKRVQAILSMLTTTSTSYLLLASLDVARKRLATQGHELAEQAIRLANETRKQI 298 Query: 301 NNIDGLYSFGKEILGTEATFNIDPTKLNIHVRHLGITGYETENWLREKYKIEVELSDMYN 360 N+ID LY GKEILGTEATF+ DPTKL I V+ LG+TGY+ E WLRE+Y IEVELSD+YN Sbjct: 299 NDIDYLYCVGKEILGTEATFDYDPTKLIISVKELGLTGYDVEKWLRERYNIEVELSDLYN 358 Query: 361 ILCLITPGDTQESVDKLISALRVLSAVHYSKGEI-YELKVQVPEIPQLALIPRDAFYADT 419 ILC+ITPGDT++ + L+ ALR LS + E+ + +V +P+IP LAL PRDAFYA+T Sbjct: 359 ILCIITPGDTEQETNVLVDALRHLSNEFRHQAEVGKKAEVILPDIPVLALTPRDAFYAET 418 Query: 420 QVVPFRESAGYIIAEFIYVYPPGIPILLPGEVITQDNIDYIIDHVEIGLPVKGPEDRSIN 479 +VVPF ESAG IIAEF+ VYPPGIPI +PGE+IT++N++YI ++E+GLPV+GPED ++ Sbjct: 419 EVVPFNESAGRIIAEFVMVYPPGIPIFIPGEIITEENLNYIRKNIEVGLPVQGPEDDTLR 478 Query: 480 YVKVIVE 486 ++VI E Sbjct: 479 TLRVIKE 485 >Q2B4X4.1 Q2B4X4_9BACI Lysine decarboxylase (LDC) Length = 489 Score = 650 bits (1678), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/490 (64%), Positives = 378/490 (77%), Gaps = 2/490 (0%) Query: 1 MDQHVTPLFTALKKHAAGNPVQFHIPGHKKGLGTDAEFREFIGDNALSIDLINIAPLDDL 60 M Q TPLF+ L HA NP+QFHIPGHKKG G D EFREFIGDNALSIDLINI PLDDL Sbjct: 1 MLQSETPLFSGLLAHAKKNPIQFHIPGHKKGAGIDPEFREFIGDNALSIDLINIGPLDDL 60 Query: 61 HQPTGVILEAQKLAAEAFGADYTYFSVQGTSNAIMTMILSVCSEGDKIIVPRNIHKSVMS 120 HQP G+I +AQ LAAEAFGAD+T+FSVQGTS AIMTM+++VC GDKIIVPRN+HKSVMS Sbjct: 61 HQPKGIIKQAQDLAAEAFGADHTFFSVQGTSGAIMTMVMAVCGPGDKIIVPRNVHKSVMS 120 Query: 121 AIIFSGAKPVFVSPVQDENLGIDHGITTSALEKALRRHPDAKGVLVINPTYFGVCADLRS 180 AI+FSGA P+F+ P DE LGI HGITT ++EKAL +HPDAKGVLVINPTYFG+ A+L+ Sbjct: 121 AIVFSGATPIFIHPEVDEKLGISHGITTDSVEKALSQHPDAKGVLVINPTYFGISANLKE 180 Query: 181 IVDLAHSYGVPVLVDEAHGVLIHFHEDLPVSAMQAGADLAATSVHKLGGSMTQSSVLNLN 240 IV++AHSY VPVLVDEAHGV IHFHEDLP+SAMQAGAD+AATSVHKLGGSMTQSS+LN+ Sbjct: 181 IVEIAHSYEVPVLVDEAHGVHIHFHEDLPMSAMQAGADMAATSVHKLGGSMTQSSILNV- 239 Query: 241 AKTGLVNPQRVQXXXXXXXXXXXXXXXXXXXDTSRRNLALNGHEMAARTIALSNYARDAI 300 K LV+P+RVQ D +RR LA G E+ RTI L+ Y R I Sbjct: 240 -KGNLVSPKRVQSILSMLTTTSTSYLLLASLDVARRRLATEGKELIERTIDLAQYMRKEI 298 Query: 301 NNIDGLYSFGKEILGTEATFNIDPTKLNIHVRHLGITGYETENWLREKYKIEVELSDMYN 360 N +D LY G EIL T+A ++ DPTKL I V+ L +TGY+ E WLREK+ IEVELSD+YN Sbjct: 299 NEVDRLYCVGDEILETKAAYDYDPTKLIISVKELNVTGYDVEKWLREKFNIEVELSDLYN 358 Query: 361 ILCLITPGDTQESVDKLISALRVLSAVHYSKGEIYELKVQVPEIPQLALIPRDAFYADTQ 420 ILC+ITPGDT++ D L++ALR LSA + E + KV +P IP L+L PRDAFYA+T+ Sbjct: 359 ILCIITPGDTKQEADALLAALRELSAGGLQETERKDAKVMLPNIPVLSLTPRDAFYAETE 418 Query: 421 VVPFRESAGYIIAEFIYVYPPGIPILLPGEVITQDNIDYIIDHVEIGLPVKGPEDRSINY 480 +VPF ES G IIAEFI VYPPGIPI +PGE+IT+DN+ YI ++E GLPV+GPED + Sbjct: 419 LVPFDESEGRIIAEFIMVYPPGIPIFIPGEIITKDNLVYIKTNMEAGLPVQGPEDYDFKF 478 Query: 481 VKVIVEAEPI 490 ++VI E + I Sbjct: 479 LRVIKEHKAI 488 >A6CTA6.1 A6CTA6_9BACI Lysine decarboxylase (LDC) Length = 494 Score = 649 bits (1675), Expect = 0.0, Method: Compositional matrix adjust. Identities = 315/492 (64%), Positives = 381/492 (77%), Gaps = 5/492 (1%) Query: 1 MDQHVTPLFTALKKHAAGNPVQFHIPGHKKGLGTDAEFREFIGDNALSIDLINIAPLDDL 60 + Q+ TPLFT L +H+ NPVQFHIPGHKKG G D EFR FIGDNA SIDLINI PLDDL Sbjct: 5 LSQYKTPLFTGLVEHSKKNPVQFHIPGHKKGTGMDPEFRNFIGDNAFSIDLINIGPLDDL 64 Query: 61 HQPTGVILEAQKLAAEAFGADYTYFSVQGTSNAIMTMILSVCSEGDKIIVPRNIHKSVMS 120 HQP G+I EAQKLAAEAFGADYT+FSVQGTS AIMTM++SVC G+KIIVPRN+HKSVMS Sbjct: 65 HQPKGMIKEAQKLAAEAFGADYTFFSVQGTSGAIMTMVMSVCGPGEKIIVPRNVHKSVMS 124 Query: 121 AIIFSGAKPVFVSPVQDENLGIDHGITTSALEKALRRHPDAKGVLVINPTYFGVCADLRS 180 AI+FSGA P+F+ P DE+LGI HGITT ++ +AL +HPDAKGVLVINPTYFG+ ADL+ Sbjct: 125 AIVFSGATPIFIHPEVDEDLGISHGITTDSVARALEQHPDAKGVLVINPTYFGISADLKK 184 Query: 181 IVDLAHSYGVPVLVDEAHGVLIHFHEDLPVSAMQAGADLAATSVHKLGGSMTQSSVLNLN 240 IV++AHS+ VPVLVDEAHGV IHFHEDLP+SAMQAGAD+AATSVHKLGGSMTQSSVLN+ Sbjct: 185 IVEIAHSFDVPVLVDEAHGVHIHFHEDLPISAMQAGADMAATSVHKLGGSMTQSSVLNI- 243 Query: 241 AKTGLVNPQRVQXXXXXXXXXXXXXXXXXXXDTSRRNLALNGHEMAARTIALSNYARDAI 300 KTGLV+P+RVQ D +R+ LA G E+ TI LS R+ + Sbjct: 244 -KTGLVSPKRVQTILSMLTTTSTSYLLLASLDVARKRLATEGRELIENTIQLSETIREKV 302 Query: 301 NNIDGLYSFGKEILGTEATFNIDPTKLNIHVRHLGITGYETENWLREKYKIEVELSDMYN 360 N I+ LY GKEILGT+ATF+ DPTKL I V+ LGI+G++ E WLRE Y IEVE+SDMYN Sbjct: 303 NRIESLYCVGKEILGTKATFDYDPTKLIISVKQLGISGFDAEKWLREVYNIEVEMSDMYN 362 Query: 361 ILCLITPGDTQESVDKLISALRVLSAVHYSKGEIYELKVQV--PEIPQLALIPRDAFYAD 418 ILC+ITPGDT DKL+ AL LS +S E + V+V P+IP L++ PRDAFYAD Sbjct: 363 ILCIITPGDTSAEGDKLVEALTELS-YQFSDKEGFSETVEVLLPDIPLLSMTPRDAFYAD 421 Query: 419 TQVVPFRESAGYIIAEFIYVYPPGIPILLPGEVITQDNIDYIIDHVEIGLPVKGPEDRSI 478 T+V+P ++ G IIAEFI VYPPGIPI +PGE+IT +N+ YI +VE GLPV+GPE+ + Sbjct: 422 TEVIPIEQTVGRIIAEFIMVYPPGIPIFIPGEIITSENLTYIQKNVEAGLPVQGPEEFDL 481 Query: 479 NYVKVIVEAEPI 490 ++++VI E + I Sbjct: 482 SHLRVIKEHKAI 493 >A8FCS7.1 A8FCS7_BACP2 Lysine decarboxylase EC=4.1.1.18 Length = 496 Score = 647 bits (1669), Expect = 0.0, Method: Compositional matrix adjust. Identities = 306/491 (62%), Positives = 383/491 (78%), Gaps = 3/491 (0%) Query: 1 MDQHVTPLFTALKKHAAGNPVQFHIPGHKKGLGTDAEFREFIGDNALSIDLINIAPLDDL 60 + QH TPL+T LKKHAA NPVQFHIPGHKKG G D EFR FIGDNALSIDLINI PLDDL Sbjct: 7 LSQHDTPLYTGLKKHAATNPVQFHIPGHKKGAGMDPEFRAFIGDNALSIDLINIEPLDDL 66 Query: 61 HQPTGVILEAQKLAAEAFGADYTYFSVQGTSNAIMTMILSVCSEGDKIIVPRNIHKSVMS 120 H P G+I EAQ LAAEAFGAD+T+F +QGTS AIMTM+++VC GDKIIVPRN+HKS+MS Sbjct: 67 HSPRGMIKEAQDLAAEAFGADHTFFCIQGTSGAIMTMVMTVCGPGDKIIVPRNVHKSIMS 126 Query: 121 AIIFSGAKPVFVSPVQDENLGIDHGITTSALEKALRRHPDAKGVLVINPTYFGVCADLRS 180 AI+FSGA PVF+ P D+ LGI HGIT + +KAL HPDAKG+LVINPTYFGV ADL+S Sbjct: 127 AIVFSGAVPVFIHPEIDKELGISHGITPESAKKALTEHPDAKGLLVINPTYFGVSADLKS 186 Query: 181 IVDLAHSYGVPVLVDEAHGVLIHFHEDLPVSAMQAGADLAATSVHKLGGSMTQSSVLNLN 240 IVD+AHS+ VPVLVDEAHGV IHFH+ LP+SAMQAGAD+AATSVHKLGGS+TQSS+LN+ Sbjct: 187 IVDIAHSFHVPVLVDEAHGVHIHFHDKLPLSAMQAGADMAATSVHKLGGSLTQSSILNM- 245 Query: 241 AKTGLVNPQRVQXXXXXXXXXXXXXXXXXXXDTSRRNLALNGHEMAARTIALSNYARDAI 300 K GL++ RVQ D +R+ LA G +A I L+ AR+ + Sbjct: 246 -KEGLISKDRVQSILSMLTTTSTSYLLLASLDVARKRLATEGKALADEAIRLAESARNRL 304 Query: 301 NNIDGLYSFGKEILGTEATFNIDPTKLNIHVRHLGITGYETENWLREKYKIEVELSDMYN 360 N IDG+ GKEILG+ +T++ DPTKL I ++ LG+ G++ E WLRE Y+IEVELSD+YN Sbjct: 305 NQIDGITCIGKEILGSASTYDYDPTKLIISIKDLGLNGHDVEKWLRESYRIEVELSDLYN 364 Query: 361 ILCLITPGDTQESVDKLISALRVLSAVHYSKGEIYEL-KVQVPEIPQLALIPRDAFYADT 419 ILC++TPGD+ E++D LI+A++ ++A S+ E+ +V +PEIP LA+ PRDAFYA T Sbjct: 365 ILCIVTPGDSDETIDALITAMKDIAATSTSESGTQEVTEVLLPEIPSLAMTPRDAFYATT 424 Query: 420 QVVPFRESAGYIIAEFIYVYPPGIPILLPGEVITQDNIDYIIDHVEIGLPVKGPEDRSIN 479 +VVPF+E+AG IIAEF+ VYPPGIPI +PGE+IT++NI YI ++EIGLPV+GPED ++ Sbjct: 425 EVVPFKEAAGRIIAEFVMVYPPGIPIFIPGEIITEENISYIFKNIEIGLPVQGPEDSTLE 484 Query: 480 YVKVIVEAEPI 490 ++VI E +PI Sbjct: 485 MIRVIKEQKPI 495 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.137 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,822,595,649 Number of extensions: 116961647 Number of successful extensions: 302177 Number of sequences better than 1.0e-05: 1449 Number of HSP's gapped: 300581 Number of HSP's successfully gapped: 1529 Length of query: 491 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 351 Effective length of database: 1,741,754,103 Effective search space: 611355690153 Effective search space used: 611355690153 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)