BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0545.0006.p (195 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KFY2.1 B3KFY2_9BACI Nicotinate (Nicotinamide) nucleotide adeny... 262 1e-68 C0ZB09.1 C0ZB09_BREBN Nicotinate-nucleotide adenylyltransferase ... 201 2e-50 B1DBK2.1 B1DBK2_9BACL Nicotinate (Nicotinamide) nucleotide adeny... 191 2e-47 Q8EPV1.1 NADD_OCEIH Probable nicotinate-nucleotide adenylyltrans... 189 1e-46 C2FEY0.1 C2FEY0_LACPA Nicotinate-nucleotide adenylyltransferase ... 178 2e-43 >B3KFY2.1 B3KFY2_9BACI Nicotinate (Nicotinamide) nucleotide adenylyltransferase EC=3.5.4.4 Length = 196 Score = 262 bits (669), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 121/191 (63%), Positives = 150/191 (78%) Query: 1 MGGTFDPLHIGHMMAAETARESYALEEVWFMPSHIPPHKHEAGASGEERLAMVEGAVRNH 60 MGGTFDP+HIGHM+AAE AR++Y LEEVWFMPSHIPPHK +AG +G RL M AV H Sbjct: 6 MGGTFDPIHIGHMLAAECARDAYDLEEVWFMPSHIPPHKEDAGVTGLMRLEMTAEAVAGH 65 Query: 61 AAFGILDLEIARGGVSYTFETITMLQEEYPEHEFFFIVGADMVQYLPKWHGIEELVRRLT 120 +F LD E+ RGGVSYT +T+ L++ YPEH+F+FI+GADMV YLPKW+ I EL LT Sbjct: 66 PSFRTLDWEVKRGGVSYTVDTVRELRDAYPEHDFYFIIGADMVAYLPKWNRIGELAEMLT 125 Query: 121 FIGVGRPGTPLDLAALPGFIAEKVLLADMPLVDISSTMLRARAAEGKSIRYMVPDAVYDY 180 FIG+ RPGT L + LP F+ + V+ A+MPL++ISST++R+RAA G SIRYMVPD VYDY Sbjct: 126 FIGLNRPGTKLSVDDLPDFLQKAVVTAEMPLIEISSTIIRSRAASGSSIRYMVPDRVYDY 185 Query: 181 VQRSGLYGTQP 191 + RSG+YG QP Sbjct: 186 IVRSGIYGLQP 196 >C0ZB09.1 C0ZB09_BREBN Nicotinate-nucleotide adenylyltransferase EC=2.7.7.18 Length = 197 Score = 201 bits (512), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 96/190 (50%), Positives = 132/190 (69%), Gaps = 6/190 (3%) Query: 1 MGGTFDPLHIGHMMAAETARESYALEEVWFMPSHIPPHK-HEAGASGEERLAMVEGAVRN 59 MGGTFDP+H GH++AAE ARE L+E+WFMP+H+PPHK E+ RL MV+ AV + Sbjct: 11 MGGTFDPIHCGHLLAAEQAREQAGLDEIWFMPTHVPPHKERESLTLAHHRLQMVQLAVSD 70 Query: 60 HAAFGILDLEIARGGVSYTFETITMLQEEYPEHEFFFIVGADMVQYLPKWHGIEELVRRL 119 H F + D+E R G SYT++T+T L ++P+ F FI+G DMV+ LPKW+ +EL+ + Sbjct: 71 HEVFRVTDVEFERKGPSYTYDTMTQLIRQFPDCRFSFIMGGDMVKILPKWYQYQELIHMV 130 Query: 120 TFIGVGRPGTPLDLAALPGFIAEKVLLADMPLVDISSTMLRARAAEGKSIRYMVPDAVYD 179 FIG+ RPGT LDL + +E V +MP+ DISSTM+R +AA KSIRY+VPDAV Sbjct: 131 RFIGLARPGTELDLKS-----SEDVTYVEMPVWDISSTMIREKAAARKSIRYLVPDAVER 185 Query: 180 YVQRSGLYGT 189 Y++ + +Y T Sbjct: 186 YIKENRIYET 195 >B1DBK2.1 B1DBK2_9BACL Nicotinate (Nicotinamide) nucleotide adenylyltransferase EC=3.5.4.4 Length = 196 Score = 191 bits (486), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 90/188 (47%), Positives = 132/188 (70%), Gaps = 1/188 (0%) Query: 1 MGGTFDPLHIGHMMAAETARESYALEEVWFMPSHIPPHK-HEAGASGEERLAMVEGAVRN 59 MGGTFDP+H GH++AAE AR+ L+EVWF+P++ PP K ++ GAS + RL MV+ A+ Sbjct: 7 MGGTFDPVHTGHLIAAEAARDGCGLDEVWFIPTYQPPLKDNQPGASSKLRLQMVQEALGG 66 Query: 60 HAAFGILDLEIARGGVSYTFETITMLQEEYPEHEFFFIVGADMVQYLPKWHGIEELVRRL 119 + AF LD+E+ RGG+SY+ +T+ L++ YP+ F +I+G+D + LPKWH IEEL + Sbjct: 67 NPAFKALDIELERGGMSYSIDTVLELKKRYPDKAFSYIIGSDRINDLPKWHRIEELAELI 126 Query: 120 TFIGVGRPGTPLDLAALPGFIAEKVLLADMPLVDISSTMLRARAAEGKSIRYMVPDAVYD 179 TFIG+ R GT + L LP ++ +V +A MP + ISST +R+R G+SI Y+VPD V Sbjct: 127 TFIGLEREGTAVQLDELPEYLRRRVTMAAMPPIGISSTEIRSRVYAGRSIAYLVPDTVQQ 186 Query: 180 YVQRSGLY 187 +++ GLY Sbjct: 187 FIKGRGLY 194 >Q8EPV1.1 NADD_OCEIH Probable nicotinate-nucleotide adenylyltransferase EC=2.7.7.18 Length = 191 Score = 189 bits (479), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 84/188 (44%), Positives = 126/188 (67%), Gaps = 7/188 (3%) Query: 1 MGGTFDPLHIGHMMAAETARESYALEEVWFMPSHIPPHKHEAGASGEERLAMVEGAVRNH 60 +GGTFDP H+GH++ AE R + L+E+WF+P++ PPHK + S + R +M++ A+ +H Sbjct: 7 LGGTFDPPHLGHLLIAEEVRRAKELDEIWFIPTNTPPHKEDTTTSADHRTSMIQLAIDSH 66 Query: 61 AAFGILDLEIARGGVSYTFETITMLQEEYPEHEFFFIVGADMVQYLPKWHGIEELVRRLT 120 +F + D+E+ R G SYT++TI L + YP H F+FI+G DMV++LPKWH I+EL+ +T Sbjct: 67 PSFKLNDMELKREGKSYTYDTIQELTDLYPSHTFYFIIGGDMVEFLPKWHRIDELLEMIT 126 Query: 121 FIGVGRPGTPLDLAALPGFIAEKVLLADMPLVDISSTMLRARAAEGKSIRYMVPDAVYDY 180 FIGV RPG L + F+ D+P + +SST+LR R + IRY++PD+V Y Sbjct: 127 FIGVSRPGYSLQTSYPVDFV-------DIPTIQLSSTILRERLQNREWIRYLLPDSVMQY 179 Query: 181 VQRSGLYG 188 V+ LYG Sbjct: 180 VREHQLYG 187 >C2FEY0.1 C2FEY0_LACPA Nicotinate-nucleotide adenylyltransferase (Deamido-NAD(+) pyrophosphorylase) EC=2.7.7.18 Length = 216 Score = 178 bits (452), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 91/188 (48%), Positives = 127/188 (67%), Gaps = 10/188 (5%) Query: 2 GGTFDPLHIGHMMAAETARESYALEEVWFMPSHIPPHKHEAGA-SGEERLAMVEGAVRNH 60 GGTF+P+H GH++ AE A LE+V+FMP + PPH A S R+ MV+ A+ ++ Sbjct: 35 GGTFNPIHNGHLIMAEAAGTELGLEKVYFMPDNQPPHVDTKTAISARHRVNMVQLAIADN 94 Query: 61 AAFGILDLEIARGGVSYTFETITMLQEEYPEHEFFFIVGADMVQYLPKWHGIEELVRRLT 120 FG+ +EI RGGVSYT+ETI L +P+ +++FI+GADMV YLPKW I+ELV+ +T Sbjct: 95 PLFGLEGIEIRRGGVSYTYETILELHRLHPDTDYYFIIGADMVDYLPKWSHIDELVKLVT 154 Query: 121 FIGVGRPG-TPLDLAALPGFIAEKVLLADMPLVDISSTMLRARAAEGKSIRYMVPDAVYD 179 F+GV R G TP + P +L D PL+DISST +R R G+S++Y+VPD+V D Sbjct: 155 FVGVKRRGYTP--ASRYP------ILWVDAPLIDISSTDVRDRVENGRSLKYLVPDSVID 206 Query: 180 YVQRSGLY 187 Y+Q+ GLY Sbjct: 207 YIQKEGLY 214 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.138 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,210,038,381 Number of extensions: 48482637 Number of successful extensions: 121239 Number of sequences better than 1.0e-05: 1262 Number of HSP's gapped: 119167 Number of HSP's successfully gapped: 1262 Length of query: 195 Length of database: 3,060,696,203 Length adjustment: 128 Effective length of query: 67 Effective length of database: 1,854,806,283 Effective search space: 124272020961 Effective search space used: 124272020961 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 127 (53.5 bits)