BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0544.0044.p (290 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B4AF34.1 B4AF34_BACPU LysR family transcriptional regulator 478 e-133 A8FC55.1 A8FC55_BACP2 LysR family transcriptional regulator 471 e-131 A3I7R5.1 A3I7R5_9BACI Transcriptional regulators, LysR family pr... 258 5e-67 A3I8L6.1 A3I8L6_9BACI Transcriptional regulator, LysR family pro... 256 1e-66 C3I0R8.1 C3I0R8_BACTU Transcriptional regulator, LysR 199 2e-49 >B4AF34.1 B4AF34_BACPU LysR family transcriptional regulator Length = 296 Score = 478 bits (1229), Expect = e-133, Method: Compositional matrix adjust. Identities = 226/288 (78%), Positives = 261/288 (90%) Query: 2 YFMAVFEHLHFTKAAEVLGISQPTLSQQIRLLEADFGIPLFDRIGKKVIVTEAGKLLHQY 61 YFMAVF+HLHFTKAAE LGISQPTLSQQIRLLEA+ G+PLFDRIGKKV+ TEAG LL+QY Sbjct: 8 YFMAVFDHLHFTKAAEQLGISQPTLSQQIRLLEAEVGMPLFDRIGKKVVATEAGSLLYQY 67 Query: 62 GMKMLQAEMDAKNAIRELRSEKRGTVRLAVLPSDLDFRLVPLFIEFKTQYPETQLQVFST 121 GMKMLQAE DAKNA++EL SEKRG VRLAVLPSDLDF+LVPLF+EFKT YP+T L+ +ST Sbjct: 68 GMKMLQAERDAKNAMKELLSEKRGNVRLAVLPSDLDFQLVPLFVEFKTLYPKTNLKAYST 127 Query: 122 IFVRDEVLAHKVDIGIGLCSPLDKRLVQVPLGSEPYYLFVHTASELAKRDEITLEEIKQH 181 IFVR+EVL+HKVD+GIGL P DKRLVQ+PLGSEPY LFVH+ SELA+++E+TLEE+ QH Sbjct: 128 IFVREEVLSHKVDLGIGLRGPADKRLVQMPLGSEPYELFVHSESELAQKNEVTLEELTQH 187 Query: 182 SLVMYPKGYLGRDLVDEVCRKQGFELPTVMEVDSASSLLQLVSAGVGVTIQPRDLLKQHL 241 +LVMYPKGYLGRDLVD+VC++QG EL TVM+V SASSLLQLV AG+G TIQPR LL+QH Sbjct: 188 ALVMYPKGYLGRDLVDDVCKEQGVELDTVMDVGSASSLLQLVEAGIGATIQPRGLLQQHA 247 Query: 242 EWSNIVSIPISEPAPIRHLELTYYADRFISKAQQKLSERLINFFQSRT 289 W NIVSIPI+EPAP+RHLEL YYADRF+SKAQQ+LSE LI+FF+SRT Sbjct: 248 TWPNIVSIPIAEPAPVRHLELIYYADRFVSKAQQQLSEWLIDFFKSRT 295 >A8FC55.1 A8FC55_BACP2 LysR family transcriptional regulator Length = 298 Score = 471 bits (1211), Expect = e-131, Method: Compositional matrix adjust. Identities = 221/288 (76%), Positives = 258/288 (89%) Query: 2 YFMAVFEHLHFTKAAEVLGISQPTLSQQIRLLEADFGIPLFDRIGKKVIVTEAGKLLHQY 61 YFMAVF+HLHFTKAAE LGISQPTLSQQIRLLEA+ G+PLFDRIGKKV+ TEAG LL+QY Sbjct: 8 YFMAVFDHLHFTKAAEQLGISQPTLSQQIRLLEAEVGMPLFDRIGKKVVATEAGSLLYQY 67 Query: 62 GMKMLQAEMDAKNAIRELRSEKRGTVRLAVLPSDLDFRLVPLFIEFKTQYPETQLQVFST 121 GMKMLQAE DAKNA++EL SEKRG VRLAVLPSDLDF+LVPLF+EFKT YPET L+ +ST Sbjct: 68 GMKMLQAERDAKNAMKELLSEKRGNVRLAVLPSDLDFQLVPLFVEFKTLYPETNLKAYST 127 Query: 122 IFVRDEVLAHKVDIGIGLCSPLDKRLVQVPLGSEPYYLFVHTASELAKRDEITLEEIKQH 181 IFVR+EVL+HKVD+GIGL P DKRL+Q+PLGSEPY LF H+ SELA++ E+TLEE+ +H Sbjct: 128 IFVREEVLSHKVDLGIGLRGPADKRLIQIPLGSEPYELFAHSESELAQKSEVTLEELTEH 187 Query: 182 SLVMYPKGYLGRDLVDEVCRKQGFELPTVMEVDSASSLLQLVSAGVGVTIQPRDLLKQHL 241 +LVMYPKGYLGRDLV++VC++QG EL TVMEV SASSLLQLV AG+G TIQPR LL+Q Sbjct: 188 ALVMYPKGYLGRDLVEDVCKEQGVELDTVMEVGSASSLLQLVEAGIGATIQPRGLLQQQA 247 Query: 242 EWSNIVSIPISEPAPIRHLELTYYADRFISKAQQKLSERLINFFQSRT 289 W NIVSIPI++PAP+RHLELTYY DRF+SKAQQ+LSE LI+FF+S+T Sbjct: 248 TWPNIVSIPIADPAPVRHLELTYYTDRFVSKAQQQLSEWLIDFFKSKT 295 >A3I7R5.1 A3I7R5_9BACI Transcriptional regulators, LysR family protein Length = 289 Score = 258 bits (659), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 134/284 (47%), Positives = 191/284 (67%), Gaps = 2/284 (0%) Query: 2 YFMAVFEHLHFTKAAEVLGISQPTLSQQIRLLEADFGIPLFDRIGKKVIVTEAGKLLHQY 61 YF+ + + LHF++AA LGISQPTLSQQIR+LE + G PLFDRIGKK + TEAG+LL Y Sbjct: 8 YFLMLCKELHFSEAAFKLGISQPTLSQQIRVLEGEIGAPLFDRIGKKTVKTEAGELLEHY 67 Query: 62 GMKMLQAEMDAKNAIRELRSEKRGTVRLAVLPSDLDFRLVPLFIEFKTQYPETQLQVFST 121 K+ Q +AK AI +L +G +R+A+LPSDLD+RL + I+F+ ++P T++QVF T Sbjct: 68 AQKVHQDLENAKKAISDLIDLNKGHLRIAILPSDLDYRLTEILIDFRKEFPNTKVQVFPT 127 Query: 122 IFVRDEVLAHKVDIGIGLCSPLDKRLVQVPLGSEPYYLFVHTASELAKRDEITLEEIKQH 181 I +VL ++VDIGIGL + L ++P +E Y LFV+ +L++R + EE+ Sbjct: 128 IKSLTKVLGNEVDIGIGLKVEANSHLERIPFYTERYSLFVNENHDLSQRKSVKPEELVDI 187 Query: 182 SLVMYPKGYLGRDLVDEVCRKQGFELPTVMEVDSASSLLQLVSAGVGVTIQPRDLLKQHL 241 LVMYP+G GRDL+D+ C +QG + +VME SA+SL QLV +G TIQP L+ ++ Sbjct: 188 PLVMYPQGKCGRDLIDKWCDRQGITINSVMETGSATSLFQLVQKDIGATIQPSQLI-ENF 246 Query: 242 EWSNIVSIPISEPAPIRHLELTYYADRFISKAQQKLSERLINFF 285 + I SIPI E AP R L++ Y D+++SKA + +R+I F Sbjct: 247 QSLGIRSIPI-ENAPTRELDIFYRNDKYLSKAAEGFMKRVIERF 289 >A3I8L6.1 A3I8L6_9BACI Transcriptional regulator, LysR family protein Length = 292 Score = 256 bits (655), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 127/285 (44%), Positives = 189/285 (66%), Gaps = 1/285 (0%) Query: 2 YFMAVFEHLHFTKAAEVLGISQPTLSQQIRLLEADFGIPLFDRIGKKVIVTEAGKLLHQY 61 YFMAV E LHFTKAAE LGISQPTLSQQIR+LE + G+PLFDRIGKK++VTEAG LL Y Sbjct: 8 YFMAVCEELHFTKAAEKLGISQPTLSQQIRVLEDELGMPLFDRIGKKIVVTEAGALLFTY 67 Query: 62 GMKMLQAEMDAKNAIRELRSEKRGTVRLAVLPSDLDFRLVPLFIEFKTQYPETQLQVFST 121 ML + K AI++L+ + G +R+ ++PSDLD+R+ L I+F ++P +L + ++ Sbjct: 68 ATAMLNTLQNVKGAIKDLQEVQGGQIRVGIMPSDLDYRITQLVIDFHQKFPRVKLTILAS 127 Query: 122 IFVRDEVLAHKVDIGIGLCSPLDKRLVQVPLGSEPYYLFVHTASELAKRDEITLEEIKQH 181 I + +VL ++VDIGIG RLV +PL E Y + V A R+ +T+ E+K Sbjct: 128 IDIMRQVLENEVDIGIGTNVEPHDRLVIIPLRKEEYVVTVSKEHPWAHREAVTIAELKDL 187 Query: 182 SLVMYPKGYLGRDLVDEVCRKQGFELPTVMEVDSASSLLQLVSAGVGVTIQPRDLLKQHL 241 LVMYP+G+LGR++V+E +K GF+L T++E S +S++ LV A +G T+QP L++Q + Sbjct: 188 PLVMYPEGFLGREIVEETVKKHGFQLHTILETSSVTSIMNLVRANIGATVQPYPLIQQ-M 246 Query: 242 EWSNIVSIPISEPAPIRHLELTYYADRFISKAQQKLSERLINFFQ 286 S++ I +++ P R L + Y DR++S A E++ + + Sbjct: 247 NDSDLRIIRLTDTIPSRSLSIIYRVDRYVSHATTAFIEQIKAYLK 291 >C3I0R8.1 C3I0R8_BACTU Transcriptional regulator, LysR Length = 300 Score = 199 bits (506), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 104/282 (36%), Positives = 174/282 (61%), Gaps = 3/282 (1%) Query: 2 YFMAVFEHLHFTKAAEVLGISQPTLSQQIRLLEADFGIPLFDRIGKKVIVTEAGKLLHQY 61 YF+AV + LHFTKAAE L ISQP+LSQQIR LE + G+PLFDRIGKK+ +TEAGK+L + Sbjct: 11 YFLAVSKQLHFTKAAEKLNISQPSLSQQIRALEHEVGMPLFDRIGKKISLTEAGKILLSH 70 Query: 62 GMKMLQAEMDAKNAIRELRSEKRGTVRLAVLPSDLDFRLVPLFIEFKTQYPETQLQVFS- 120 + A++AI++L ++G++ + L + +++ L P + F YP +L V Sbjct: 71 CKTIFHEVEQARSAIQDLNGLQQGSLTIGALLTVVNYLLPPAILNFNNLYPNIELSVLGL 130 Query: 121 -TIFVRDEVLAHKVDIGIGLCSPLDKRLVQVPLGSEPYYLFVHTASELAKRDEITLEEIK 179 T +R+++L +++DIGI DK ++ +PL L V T LA+R+ +++ E++ Sbjct: 131 RTGDIREKLLQNELDIGITFLPVQDKEIISIPLYKSDLTLVVPTGHRLAERNHVSIAELQ 190 Query: 180 QHSLVMYPKGYLGRDLVDEVCRKQGFELPTVMEVDSASSLLQLVSAGVGVTIQPRDLLKQ 239 +SL++ PK + +L+ C+K F+ ++E+ + SL+Q+VS G+G+T+ P+ + Sbjct: 191 NYSLILLPKNFFLTELITSHCQKLNFKPRPILEISTMESLIQMVSKGMGITVLPKPYI-D 249 Query: 240 HLEWSNIVSIPISEPAPIRHLELTYYADRFISKAQQKLSERL 281 L+ NI +I I P PI + L Y D+++ A ++ E+L Sbjct: 250 FLQNKNIQAIRIENPTPIIEIGLIYRKDKYMCAATREFIEQL 291 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.139 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,600,425,960 Number of extensions: 64027202 Number of successful extensions: 198065 Number of sequences better than 1.0e-05: 16256 Number of HSP's gapped: 190084 Number of HSP's successfully gapped: 16256 Length of query: 290 Length of database: 3,060,696,203 Length adjustment: 134 Effective length of query: 156 Effective length of database: 1,798,280,193 Effective search space: 280531710108 Effective search space used: 280531710108 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 130 (54.7 bits)