BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0544.0037.p (431 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DF83.1 B1DF83_9BACL Dihydrolipoamide dehydrogenase 669 0.0 C0ZDW9.1 C0ZDW9_BREBN Dihydrolipoyl dehydrogenase EC=1.8.1.4 639 0.0 B4AF32.1 B4AF32_BACPU Dihydrolipoyl dehydrogenase EC=1.8.1.4 563 e-158 P11959.2 DLDH1_BACST Dihydrolipoyl dehydrogenase EC=1.8.1.4 445 e-123 Q5L134.1 Q5L134_GEOKA Dihydrolipoyl dehydrogenase EC=1.8.1.4 443 e-122 >B1DF83.1 B1DF83_9BACL Dihydrolipoamide dehydrogenase Length = 460 Score = 669 bits (1726), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/426 (79%), Positives = 391/426 (91%) Query: 1 VVERGQIGGVCTNVGCIPSKALIAEAHRFHSHKTWSRSGSIDAFLEAQAFKESIVTKQSG 60 VVERG IGG+CTNVGCIPSKALIAEAHR+HS + WSRS S+D+F EAQAFKE++V KQSG Sbjct: 34 VVERGPIGGICTNVGCIPSKALIAEAHRYHSRRLWSRSSSVDSFEEAQAFKEAVVNKQSG 93 Query: 61 GVKYLLQTAGATILEGEASFIDRHTVRIEQPGTELLVSFKHAILATGSRPIELQALPFGN 120 GV+YLL++AG T+LEGEASFID HT RI Q TE V+FK+AILATGSRP+EL+A+PFG+ Sbjct: 94 GVQYLLKSAGVTVLEGEASFIDEHTARITQLETEQAVAFKYAILATGSRPVELKAIPFGS 153 Query: 121 RILSSTEALSLASIPESLIVIGGGYIGVELGQMYAKFGSKVTILEGGQRVLPGFEADLVA 180 R+LSSTEALSLASIPESLIVIGGGYIGVELGQMYAKFGSKVTILEGGQ+VLPGFEADLVA Sbjct: 154 RVLSSTEALSLASIPESLIVIGGGYIGVELGQMYAKFGSKVTILEGGQQVLPGFEADLVA 213 Query: 181 PVIKHMSADGITIVTEATAVSAKQDLDGLTLNYIKNDVPYSIRAEYALITVGRKPNTDGG 240 PV+K M+ADG+TIVTEATAV A+QD +G+TL+Y+ NDV +SIRA+YAL+TVGR+PNTDG Sbjct: 214 PVMKQMNADGMTIVTEATAVRAEQDSEGITLHYVGNDVRHSIRADYALVTVGRRPNTDGS 273 Query: 241 LGLERIGLHPTSKGLIDTDKQCRTEVSNIFAIGDITSGPALAHKASFEANVAAEAIAGLQ 300 LGL+RIGL TSKGL+ TDKQCRTEV ++FAIGDIT GPALAHKAS+EA VAAEAIAGL Sbjct: 274 LGLDRIGLRTTSKGLMGTDKQCRTEVPHVFAIGDITEGPALAHKASYEAIVAAEAIAGLP 333 Query: 301 TIIDYKAIPLVVFSGPELSSVGMSETECKAIAMPAIVGRSSFAINGRALALKSAEGFVKI 360 T+IDYK IPLVVFSGPEL+SVG+SETECKA A+P I GRSSF INGRALA+++ EGFVK+ Sbjct: 334 TMIDYKVIPLVVFSGPELASVGLSETECKAKAIPTIAGRSSFGINGRALAVRAPEGFVKV 393 Query: 361 IAHSESGIILGAQIVGAEASTLISELGLAIEMGATVEDLALTIHPHPTLGEVIMEAAQNA 420 IAH+E+G+I+GAQIVGAEASTL+SEL LAIEMGATVEDLALTIHPHPTLGEVIMEAAQNA Sbjct: 394 IAHAETGLIMGAQIVGAEASTLVSELSLAIEMGATVEDLALTIHPHPTLGEVIMEAAQNA 453 Query: 421 VRKIMK 426 V+++ K Sbjct: 454 VKRLAK 459 >C0ZDW9.1 C0ZDW9_BREBN Dihydrolipoyl dehydrogenase EC=1.8.1.4 Length = 471 Score = 639 bits (1648), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/432 (72%), Positives = 376/432 (87%), Gaps = 1/432 (0%) Query: 1 VVERGQIGGVCTNVGCIPSKALIAEAHRFHSHKTWSRSGSIDAFLEAQAFKESIVTKQSG 60 VVERGQIGGVCTN+GCIPSK+LIAEAHR++ H W+ + + +F EAQAFK+++V KQSG Sbjct: 34 VVERGQIGGVCTNIGCIPSKSLIAEAHRYNLHSQWNHAVASVSFEEAQAFKQAVVNKQSG 93 Query: 61 GVKYLLQTAGATILEGEASFIDRHTVRIEQPGTELLVSFKHAILATGSRPIELQALPFGN 120 GV YLL++AG TILEGEASFID+HTV ++ P TE L+SFK+AILATGSRPIELQALPFG+ Sbjct: 94 GVHYLLRSAGVTILEGEASFIDQHTVVMKGPETEQLISFKYAILATGSRPIELQALPFGD 153 Query: 121 RILSSTEALSLASIPESLIVIGGGYIGVELGQMYAKFGSKVTILEGGQRVLPGFEADLVA 180 RILSSTEALSL+ +P SL+VIGGGYIGVELGQM+AKFG+KVTILEGG++VLPGFEADL A Sbjct: 154 RILSSTEALSLSQLPASLVVIGGGYIGVELGQMFAKFGTKVTILEGGEQVLPGFEADLTA 213 Query: 181 PVIKHMSADGITIVTEATAVSAKQDLDGLTLNYIKNDVPYSIRAEYALITVGRKPNTDGG 240 V + ++ DG+TI+T A AV A+QD +GLTL+Y+KND + +R EYAL+TVGRKPNTDG Sbjct: 214 LVGRQLNTDGVTIITGAKAVKAEQDTEGLTLHYLKNDEEHLVRTEYALVTVGRKPNTDGS 273 Query: 241 LGLERIGLHPTSKGLIDTDKQCRTEVSNIFAIGDITSGPALAHKASFEANVAAEAIAGLQ 300 LGL RIGL TS+GL++TD+QCRT + +IFAIGDI +GP LAHKAS+EA VAAEAIAG Sbjct: 274 LGLNRIGLPTTSRGLLETDEQCRTAIPHIFAIGDIANGPGLAHKASYEAKVAAEAIAGEP 333 Query: 301 TIIDYKAIPLVVFSGPELSSVGMSETECKAIAMPAIVGRSSFAINGRALALKSAEGFVKI 360 + +DYKAIPLVVFS PEL+SVG++ETECKA A+P +VG+SSF+INGRALALK+A GFVK+ Sbjct: 334 SAVDYKAIPLVVFSEPELASVGLTETECKAKAVPVVVGKSSFSINGRALALKAAVGFVKV 393 Query: 361 IAHSESGIILGAQIVGAEASTLISELGLAIEMGATVEDLALTIHPHPTLGEVIMEAAQNA 420 +A SGI++GAQIVGAEASTLISEL LAIEMGATVEDLA+TIHPHPT+GEVIMEAA NA Sbjct: 394 VADPVSGIVMGAQIVGAEASTLISELALAIEMGATVEDLAMTIHPHPTMGEVIMEAAGNA 453 Query: 421 VRKIMK-TKIQT 431 +K K KIQ+ Sbjct: 454 AKKHKKINKIQS 465 >B4AF32.1 B4AF32_BACPU Dihydrolipoyl dehydrogenase EC=1.8.1.4 Length = 464 Score = 563 bits (1450), Expect = e-158, Method: Compositional matrix adjust. Identities = 283/427 (66%), Positives = 357/427 (83%), Gaps = 1/427 (0%) Query: 1 VVERGQIGGVCTNVGCIPSKALIAEAHRFHSHKTWSRSGSIDAFLEAQAFKESIVTKQSG 60 +VER Q+GGVCT+VGCIPSKALIAEA RF W +F EAQAFK+++V KQ+G Sbjct: 34 IVERDQLGGVCTHVGCIPSKALIAEAERFKLRTQWGVFQEGGSFKEAQAFKKAVVKKQAG 93 Query: 61 GVKYLLQTAGATILEGEASFIDRHTVRIEQPGT-ELLVSFKHAILATGSRPIELQALPFG 119 GV++LL++AG TILEGEAS ID+HT I+ E ++FKH ILATGSRPIE+++LPFG Sbjct: 94 GVQFLLKSAGVTILEGEASLIDQHTAMIQHAEKGEKRINFKHLILATGSRPIEMRSLPFG 153 Query: 120 NRILSSTEALSLASIPESLIVIGGGYIGVELGQMYAKFGSKVTILEGGQRVLPGFEADLV 179 RILSSTEALSL +IP+SL+V+GGGYIGVELGQM+A+FG++VTILEGG ++LPGFE++LV Sbjct: 154 GRILSSTEALSLPNIPKSLVVVGGGYIGVELGQMFARFGAEVTILEGGNQILPGFESELV 213 Query: 180 APVIKHMSADGITIVTEATAVSAKQDLDGLTLNYIKNDVPYSIRAEYALITVGRKPNTDG 239 +PVI+ + D IT++T A +A+Q + G+ L+Y + Y+++AEYALITVGRKPNTDG Sbjct: 214 SPVIRQLKEDHITVITGANVKNAEQHMSGIDLHYERQKESYTVKAEYALITVGRKPNTDG 273 Query: 240 GLGLERIGLHPTSKGLIDTDKQCRTEVSNIFAIGDITSGPALAHKASFEANVAAEAIAGL 299 LGL+ IGL T GLI+ D+QCRT + +I+AIGDIT GPALAHKAS+EA VAAEAIAG Sbjct: 274 SLGLDSIGLSITPHGLIEVDEQCRTSIPHIYAIGDITKGPALAHKASYEAKVAAEAIAGK 333 Query: 300 QTIIDYKAIPLVVFSGPELSSVGMSETECKAIAMPAIVGRSSFAINGRALALKSAEGFVK 359 ++IDYKAIPLVVFS PEL+SVG+SET+CK ++P ++G++ F+INGRALALK +EGFVK Sbjct: 334 PSMIDYKAIPLVVFSSPELASVGLSETDCKQQSIPTVIGKTMFSINGRALALKESEGFVK 393 Query: 360 IIAHSESGIILGAQIVGAEASTLISELGLAIEMGATVEDLALTIHPHPTLGEVIMEAAQN 419 I+AH+ESG+ILGAQIVGAEASTLISEL L+IE+GATVEDLA+TIHPHPTLGE+IMEAA+ Sbjct: 394 IVAHAESGLILGAQIVGAEASTLISELSLSIEIGATVEDLAMTIHPHPTLGEMIMEAAEM 453 Query: 420 AVRKIMK 426 A RK+ K Sbjct: 454 ATRKVEK 460 >P11959.2 DLDH1_BACST Dihydrolipoyl dehydrogenase EC=1.8.1.4 Length = 470 Score = 445 bits (1144), Expect = e-123, Method: Compositional matrix adjust. Identities = 230/427 (53%), Positives = 298/427 (69%), Gaps = 8/427 (1%) Query: 1 VVERGQIGGVCTNVGCIPSKALIAEAHRFHSHKTWSRSG------SIDAFLEAQAFKESI 54 +VE+G +GGVC NVGCIPSKALI+ +HR+ K G +ID F + Q +K S+ Sbjct: 37 IVEKGNLGGVCLNVGCIPSKALISASHRYEQAKHSEEMGIKAENVTID-FAKVQEWKASV 95 Query: 55 VTKQSGGVKYLLQTAGATILEGEASFIDRHTVRIEQPGTELLVSFKHAILATGSRPIELQ 114 V K +GGV+ LL+ I++GEA F+D +TVR+ + +FK+AI+ATGSRPIEL Sbjct: 96 VKKLTGGVEGLLKGNKVEIVKGEAYFVDANTVRVVNGDSAQTYTFKNAIIATGSRPIELP 155 Query: 115 ALPFGNRILSSTEALSLASIPESLIVIGGGYIGVELGQMYAKFGSKVTILEGGQRVLPGF 174 F NRIL ST AL+L +P+SL+VIGGGYIG+ELG YA FG+KVTILEG +L GF Sbjct: 156 NFKFSNRILDSTGALNLGEVPKSLVVIGGGYIGIELGTAYANFGTKVTILEGAGEILSGF 215 Query: 175 EADLVAPVIKHMSADGITIVTEATAVSAKQDLDGLTLNYIKNDVPYSIRAEYALITVGRK 234 E + A + K + G+ +VT A A A++ DG+T+ Y N +I A+Y L+TVGR+ Sbjct: 216 EKQMAAIIKKRLKKKGVEVVTNALAKGAEEREDGVTVTYEANGETKTIDADYVLVTVGRR 275 Query: 235 PNTDGGLGLERIGLHPTSKGLIDTDKQCRTEVSNIFAIGDITSGPALAHKASFEANVAAE 294 PNTD LGLE+IG+ T++GLI+ D+QCRT V NIFAIGDI GPALAHKAS+E VAAE Sbjct: 276 PNTDE-LGLEQIGIKMTNRGLIEVDQQCRTSVPNIFAIGDIVPGPALAHKASYEGKVAAE 334 Query: 295 AIAGLQTIIDYKAIPLVVFSGPELSSVGMSETECKAIAMPAIVGRSSFAINGRALALKSA 354 AIAG + +DY AIP VVFS PE +SVG E + K + I + FA NGRALAL Sbjct: 335 AIAGHPSAVDYVAIPAVVFSDPECASVGYFEQQAKDEGIDVIAAKFPFAANGRALALNDT 394 Query: 355 EGFVKIIAHSESGIILGAQIVGAEASTLISELGLAIEMGATVEDLALTIHPHPTLGEVIM 414 +GF+K++ E G+I+GAQI+G AS +I+ELGLAIE G T ED+ALTIH HPTLGE+ M Sbjct: 395 DGFLKLVVRKEDGVIIGAQIIGPNASDMIAELGLAIEAGMTAEDIALTIHAHPTLGEIAM 454 Query: 415 EAAQNAV 421 EAA+ A+ Sbjct: 455 EAAEVAL 461 >Q5L134.1 Q5L134_GEOKA Dihydrolipoyl dehydrogenase EC=1.8.1.4 Length = 470 Score = 443 bits (1140), Expect = e-122, Method: Compositional matrix adjust. Identities = 228/427 (53%), Positives = 299/427 (70%), Gaps = 8/427 (1%) Query: 1 VVERGQIGGVCTNVGCIPSKALIAEAHRFHSHKTWSRSG------SIDAFLEAQAFKESI 54 +VE+G +GGVC NVGCIPSKALI+ +HR+ K G ++D F + Q +K SI Sbjct: 37 IVEKGNLGGVCLNVGCIPSKALISASHRYEQAKHSEEMGIKAENVTVD-FSKVQEWKASI 95 Query: 55 VTKQSGGVKYLLQTAGATILEGEASFIDRHTVRIEQPGTELLVSFKHAILATGSRPIELQ 114 V K +GGV+ LL+ I++GEA F+D +TVR+ + +FK+AILATGSRPIEL Sbjct: 96 VKKLTGGVEGLLKGNKVDIVKGEAYFVDANTVRVVNGDSAQTYTFKNAILATGSRPIELP 155 Query: 115 ALPFGNRILSSTEALSLASIPESLIVIGGGYIGVELGQMYAKFGSKVTILEGGQRVLPGF 174 F RIL ST AL+L IP+SL+VIGGGYIG+ELG YA FG+KVTILEG +L GF Sbjct: 156 NFKFSGRILDSTGALNLGEIPKSLVVIGGGYIGIELGTAYANFGAKVTILEGAGEILSGF 215 Query: 175 EADLVAPVIKHMSADGITIVTEATAVSAKQDLDGLTLNYIKNDVPYSIRAEYALITVGRK 234 E +V+ + + + G+ +VT A A A++ DG+T+ Y N +I A+Y L+TVGR+ Sbjct: 216 EKQMVSIIKRRLKNKGVEVVTNALAKGAEERADGVTVTYEANGETKTIDADYVLVTVGRR 275 Query: 235 PNTDGGLGLERIGLHPTSKGLIDTDKQCRTEVSNIFAIGDITSGPALAHKASFEANVAAE 294 PNTD LGLE+IG+ T++GLI+ D+QCRT V NIFAIGDI GPALAHKAS+E VAAE Sbjct: 276 PNTDE-LGLEQIGIKMTNRGLIEVDQQCRTSVPNIFAIGDIVPGPALAHKASYEGKVAAE 334 Query: 295 AIAGLQTIIDYKAIPLVVFSGPELSSVGMSETECKAIAMPAIVGRSSFAINGRALALKSA 354 AIAG +++DY AIP VVFS PE +SVG E + K + I + FA NGRAL+L Sbjct: 335 AIAGHPSVVDYIAIPAVVFSDPECASVGYFEQQAKEEGIDVITAKFPFAANGRALSLNDT 394 Query: 355 EGFVKIIAHSESGIILGAQIVGAEASTLISELGLAIEMGATVEDLALTIHPHPTLGEVIM 414 +GF+K++ E G+++GAQI+G AS +I+ELGLAIE G T ED+ALTIH HPTLGE+ M Sbjct: 395 DGFLKLVVRKEDGVVIGAQIIGPNASDMIAELGLAIEAGMTAEDIALTIHAHPTLGEIAM 454 Query: 415 EAAQNAV 421 EAA+ A+ Sbjct: 455 EAAEVAL 461 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.134 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,321,445,603 Number of extensions: 92814533 Number of successful extensions: 333769 Number of sequences better than 1.0e-05: 6517 Number of HSP's gapped: 310681 Number of HSP's successfully gapped: 6551 Length of query: 431 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 292 Effective length of database: 1,751,175,118 Effective search space: 511343134456 Effective search space used: 511343134456 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 133 (55.8 bits)