BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0544.0006.p (485 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C3BIT0.1 C3BIT0_9BACI Zn-dependent hydrolase 716 0.0 C3AK63.1 C3AK63_BACMY Zn-dependent hydrolase 715 0.0 C3B228.1 C3B228_BACMY Zn-dependent hydrolase 714 0.0 C3H2W4.1 C3H2W4_BACTU Zn-dependent hydrolase 707 0.0 C2X0E1.1 C2X0E1_BACCE Zn-dependent hydrolase 706 0.0 >C3BIT0.1 C3BIT0_9BACI Zn-dependent hydrolase Length = 557 Score = 716 bits (1847), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/487 (69%), Positives = 406/487 (83%), Gaps = 2/487 (0%) Query: 1 VTHGHEDHIGGIPYFLKQLNIPVYASRLTLGLIQTKLKEHGLLRQTQLNCIDTESTLNFG 60 VTHGHEDHIGGIPY LKQLN+P+YA++LT+GLI KLKEHGL TQL ID+ES + FG Sbjct: 71 VTHGHEDHIGGIPYLLKQLNVPIYATKLTIGLIGIKLKEHGLQNLTQLFVIDSESVIEFG 130 Query: 61 SITITFFRTNHSIPDCLGIVFDTPEGTVVHTGDFKFDMTPVNKQYPDIHKMAAIGEKGVK 120 SI++TFF+TNHSIPDCLGI F TPEGTVVHTGDFKFD+TPVN QYPDIHKMA IG GV Sbjct: 131 SISLTFFKTNHSIPDCLGIAFYTPEGTVVHTGDFKFDLTPVNNQYPDIHKMAKIGSGGVL 190 Query: 121 FLLSESTNAERPGFTPSERLVGAHLEEAFHKAENRIFISTFASNVHRLQQIVDAAGHTGR 180 LLSESTNAERPGFTPSER VG +EEAF KA ++ +STFASNV+R+QQ+VDAA T R Sbjct: 191 ALLSESTNAERPGFTPSERSVGERIEEAFIKARRKVIVSTFASNVNRVQQVVDAAIKTNR 250 Query: 181 KLALLGRSMVNVVGVAQELGYLNIPEGMLVEPAEAGKMDRGRIAVLCTGSQGEPMAALSR 240 KLALLGRSMVNVV VA E GYLNIPEGML+E E +MD R+A+LCTGSQGEPMAALSR Sbjct: 251 KLALLGRSMVNVVSVALEQGYLNIPEGMLIEANEINQMDPERVAILCTGSQGEPMAALSR 310 Query: 241 LANSSHRQLEISEGDTVLLAANPIPGNERNVSRIVDNLYMLGARVIYGSRSE--LHVSGH 298 LA+ ++RQ++I DTV+LAA PIPGNERNVSRI+DNL++LGA VIYGS S +HVSGH Sbjct: 311 LASGNYRQVDILSEDTVILAATPIPGNERNVSRIIDNLFLLGANVIYGSGSSTGMHVSGH 370 Query: 299 GSQEELKLMLTLMKPEYFIPIHGEYRMLHHHSMLAEAVGVKNENIFILKNGDIVESNAGD 358 QEELKLMLTLMKP+YFIPIHGE+RMLHHHS+LAE+VGVK ENI+++ NGD+V+ Sbjct: 371 AYQEELKLMLTLMKPKYFIPIHGEFRMLHHHSLLAESVGVKKENIYVISNGDVVDIKNQV 430 Query: 359 VRQSGRITAGQIYVDGLGIGDIGNVVLRDRRQLSADGILITVITLSQNDGRILNDPDTIS 418 +S RI AG IYVDGLGIGD+GN +LRDR+QLS DG+L+ VITLS+ +G+I++ PD IS Sbjct: 431 AWKSRRIPAGNIYVDGLGIGDVGNAILRDRKQLSEDGMLVIVITLSKTEGKIISGPDMIS 490 Query: 419 RGFVYVRNSDTLMEEINQLITSTLQKMSAADLGQWNIIKETIKETLGKFLYERTKRRPMI 478 RGFVYVR+S+ ++ INQL+ +T+ + ++ QWN++K+ I+E LG+F+Y TKR+PMI Sbjct: 491 RGFVYVRDSEEFLQRINQLVVTTINNLQKENVSQWNVLKKEIREVLGQFVYSHTKRKPMI 550 Query: 479 LPIIIEV 485 LPIIIEV Sbjct: 551 LPIIIEV 557 >C3AK63.1 C3AK63_BACMY Zn-dependent hydrolase Length = 557 Score = 715 bits (1846), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/487 (68%), Positives = 407/487 (83%), Gaps = 2/487 (0%) Query: 1 VTHGHEDHIGGIPYFLKQLNIPVYASRLTLGLIQTKLKEHGLLRQTQLNCIDTESTLNFG 60 VTHGHEDHIGGIPY LKQLN+P+YA++LT+GLI KLKEHGL TQL ID+ES + FG Sbjct: 71 VTHGHEDHIGGIPYLLKQLNVPIYATKLTIGLIGIKLKEHGLQNLTQLFVIDSESVIEFG 130 Query: 61 SITITFFRTNHSIPDCLGIVFDTPEGTVVHTGDFKFDMTPVNKQYPDIHKMAAIGEKGVK 120 SI++TFF+TNHSIPDCLGI F TPEGTVVHTGDFKFD+TPVN QYPDIHKMA IG GV Sbjct: 131 SISLTFFKTNHSIPDCLGIAFYTPEGTVVHTGDFKFDLTPVNNQYPDIHKMAKIGSGGVL 190 Query: 121 FLLSESTNAERPGFTPSERLVGAHLEEAFHKAENRIFISTFASNVHRLQQIVDAAGHTGR 180 LLSESTNAERPGFTPSER VG +EEAF KA ++ +STFASNV+R+QQ+VDAA T R Sbjct: 191 ALLSESTNAERPGFTPSERSVGERIEEAFIKARRKVIVSTFASNVNRVQQVVDAAIKTNR 250 Query: 181 KLALLGRSMVNVVGVAQELGYLNIPEGMLVEPAEAGKMDRGRIAVLCTGSQGEPMAALSR 240 KLALLG+SMVNVV VA E GYLNIPEGML+E E +MD R+A+LCTGSQGEPMAALSR Sbjct: 251 KLALLGKSMVNVVSVALEQGYLNIPEGMLIEANEINQMDPERVAILCTGSQGEPMAALSR 310 Query: 241 LANSSHRQLEISEGDTVLLAANPIPGNERNVSRIVDNLYMLGARVIYGSRSE--LHVSGH 298 LA+ ++RQ++I DTV+LAA PIPGNERNVSRI+DNL++LGA+VIYGS S +HVSGH Sbjct: 311 LASGNYRQVDILSEDTVILAATPIPGNERNVSRIIDNLFLLGAKVIYGSGSSTGMHVSGH 370 Query: 299 GSQEELKLMLTLMKPEYFIPIHGEYRMLHHHSMLAEAVGVKNENIFILKNGDIVESNAGD 358 QEELKLMLTLMKP+YFIPIHGE+RMLHHHS+LAE+VGVK E+I+++ NGD+V+ Sbjct: 371 AYQEELKLMLTLMKPKYFIPIHGEFRMLHHHSLLAESVGVKKEDIYVISNGDVVDIKNQV 430 Query: 359 VRQSGRITAGQIYVDGLGIGDIGNVVLRDRRQLSADGILITVITLSQNDGRILNDPDTIS 418 +S RI AG IYVDGLGIGD+GN +LRDR+QLS DG+L+ VITLS+ +G+I++ PD IS Sbjct: 431 AWKSRRIPAGNIYVDGLGIGDVGNAILRDRKQLSEDGMLVIVITLSKTEGKIISGPDMIS 490 Query: 419 RGFVYVRNSDTLMEEINQLITSTLQKMSAADLGQWNIIKETIKETLGKFLYERTKRRPMI 478 RGFVYVR+S+ ++ INQL+ +T+ + ++ QWN++K+ IKE LG+F+Y TKR+PMI Sbjct: 491 RGFVYVRDSEDFLQRINQLVVTTINNLQKENVSQWNVLKKEIKEVLGQFVYSHTKRKPMI 550 Query: 479 LPIIIEV 485 LPIIIEV Sbjct: 551 LPIIIEV 557 >C3B228.1 C3B228_BACMY Zn-dependent hydrolase Length = 557 Score = 714 bits (1843), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/487 (68%), Positives = 406/487 (83%), Gaps = 2/487 (0%) Query: 1 VTHGHEDHIGGIPYFLKQLNIPVYASRLTLGLIQTKLKEHGLLRQTQLNCIDTESTLNFG 60 VTHGHEDHIGGIPY LKQLN+P+YA++LT+GLI KLKEHGL TQL ID+ES + FG Sbjct: 71 VTHGHEDHIGGIPYLLKQLNVPIYATKLTIGLIGIKLKEHGLQNLTQLFVIDSESVIEFG 130 Query: 61 SITITFFRTNHSIPDCLGIVFDTPEGTVVHTGDFKFDMTPVNKQYPDIHKMAAIGEKGVK 120 SI++TFF+TNHSIPDCLGI F TPEGTVVHTGDFKFD+TPVN QYPDIHKMA IG GV Sbjct: 131 SISLTFFKTNHSIPDCLGIAFYTPEGTVVHTGDFKFDLTPVNNQYPDIHKMAKIGSGGVL 190 Query: 121 FLLSESTNAERPGFTPSERLVGAHLEEAFHKAENRIFISTFASNVHRLQQIVDAAGHTGR 180 LLSESTNAERPGFTPSER VG +EEAF KA ++ +STFASNV+R+QQ+VDAA T R Sbjct: 191 ALLSESTNAERPGFTPSERSVGERIEEAFIKARRKVIVSTFASNVNRVQQVVDAAIKTNR 250 Query: 181 KLALLGRSMVNVVGVAQELGYLNIPEGMLVEPAEAGKMDRGRIAVLCTGSQGEPMAALSR 240 KLALLG+SMVNVV VA E GYLNIPEGML+E E +MD R+A+LCTGSQGEPMAALSR Sbjct: 251 KLALLGKSMVNVVSVALEQGYLNIPEGMLIEANEINQMDPERVAILCTGSQGEPMAALSR 310 Query: 241 LANSSHRQLEISEGDTVLLAANPIPGNERNVSRIVDNLYMLGARVIYGSRSE--LHVSGH 298 LA+ ++RQ++I DTV+LAA PIPGNERNVSRI+DNL++LGA VIYGS S +HVSGH Sbjct: 311 LASGNYRQVDILSEDTVILAATPIPGNERNVSRIIDNLFLLGAEVIYGSGSSTGMHVSGH 370 Query: 299 GSQEELKLMLTLMKPEYFIPIHGEYRMLHHHSMLAEAVGVKNENIFILKNGDIVESNAGD 358 QEELKLMLTLMKP+YFIPIHGE+RMLHHHS+LAE+VGVK E+I+++ NGD+V+ Sbjct: 371 AYQEELKLMLTLMKPKYFIPIHGEFRMLHHHSLLAESVGVKKEDIYVISNGDVVDIKNQV 430 Query: 359 VRQSGRITAGQIYVDGLGIGDIGNVVLRDRRQLSADGILITVITLSQNDGRILNDPDTIS 418 +S RI AG IYVDGLGIGD+GN +LRDR+QLS DG+L+ VITLS+ +G+I++ PD IS Sbjct: 431 AWKSRRIPAGNIYVDGLGIGDVGNAILRDRKQLSEDGMLVIVITLSKTEGKIISGPDMIS 490 Query: 419 RGFVYVRNSDTLMEEINQLITSTLQKMSAADLGQWNIIKETIKETLGKFLYERTKRRPMI 478 RGFVYVR+S+ ++ INQL+ +T+ + ++ QWN++K+ IKE LG+F+Y TKR+PMI Sbjct: 491 RGFVYVRDSEDFLQRINQLVVTTINNLQKENVSQWNVLKKEIKEVLGQFVYSHTKRKPMI 550 Query: 479 LPIIIEV 485 LPIIIEV Sbjct: 551 LPIIIEV 557 >C3H2W4.1 C3H2W4_BACTU Zn-dependent hydrolase Length = 557 Score = 707 bits (1824), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/487 (68%), Positives = 405/487 (83%), Gaps = 2/487 (0%) Query: 1 VTHGHEDHIGGIPYFLKQLNIPVYASRLTLGLIQTKLKEHGLLRQTQLNCIDTESTLNFG 60 VTHGHEDHIGGIPYFLKQLN+P+YA++LTLGLI KLKEH L TQL ID+ES + FG Sbjct: 71 VTHGHEDHIGGIPYFLKQLNVPIYATKLTLGLIGIKLKEHKLQDSTQLIVIDSESLIEFG 130 Query: 61 SITITFFRTNHSIPDCLGIVFDTPEGTVVHTGDFKFDMTPVNKQYPDIHKMAAIGEKGVK 120 I ++FF+TNHSIPDCLGI F TPEGTVVHTGDFKFD+TP+N QYPDIHKMA IG GV Sbjct: 131 QINLSFFKTNHSIPDCLGIAFHTPEGTVVHTGDFKFDLTPINNQYPDIHKMANIGSNGVL 190 Query: 121 FLLSESTNAERPGFTPSERLVGAHLEEAFHKAENRIFISTFASNVHRLQQIVDAAGHTGR 180 LLSESTNAER GFTPSERLVG +EEAF KA +++ ISTFASNV+R+QQIVDAA T R Sbjct: 191 ALLSESTNAERSGFTPSERLVGEKIEEAFVKAHSKVIISTFASNVNRVQQIVDAALKTNR 250 Query: 181 KLALLGRSMVNVVGVAQELGYLNIPEGMLVEPAEAGKMDRGRIAVLCTGSQGEPMAALSR 240 KLALLGRSMVNVV VA E GYLNIPEGML+E E +M+ ++A+LCTGSQGEPMAALSR Sbjct: 251 KLALLGRSMVNVVSVALEQGYLNIPEGMLIEANEINQMEPEKVAILCTGSQGEPMAALSR 310 Query: 241 LANSSHRQLEISEGDTVLLAANPIPGNERNVSRIVDNLYMLGARVIY--GSRSELHVSGH 298 L++ ++RQ++I GDTV+L+A+PIPGNERNVSRI+DNLY+LGA VIY GS + +HVSGH Sbjct: 311 LSSGNYRQVDILPGDTVILSASPIPGNERNVSRIIDNLYLLGANVIYRSGSSTGMHVSGH 370 Query: 299 GSQEELKLMLTLMKPEYFIPIHGEYRMLHHHSMLAEAVGVKNENIFILKNGDIVESNAGD 358 QEELKLMLTLMKP+YFIPIHGE+RMLHHH LAE+VGVK +NI+++ NGD+V+ Sbjct: 371 AYQEELKLMLTLMKPKYFIPIHGEFRMLHHHRQLAESVGVKKDNIYVIGNGDVVDIKNQT 430 Query: 359 VRQSGRITAGQIYVDGLGIGDIGNVVLRDRRQLSADGILITVITLSQNDGRILNDPDTIS 418 Q+ RITAG IYVDGLGIGD+GN +LRDR+QLS DG+L+ VITLS+ + +I++ PDTIS Sbjct: 431 AMQTRRITAGNIYVDGLGIGDVGNALLRDRKQLSEDGMLVIVITLSKTEEKIISGPDTIS 490 Query: 419 RGFVYVRNSDTLMEEINQLITSTLQKMSAADLGQWNIIKETIKETLGKFLYERTKRRPMI 478 RGFVYVR+S+ + +INQL+ T+ ++ A + QWN++K I+E+LG F+Y TKR+PMI Sbjct: 491 RGFVYVRDSEDFLNKINQLVVETVNRLQKAHINQWNVLKREIRESLGHFIYSHTKRKPMI 550 Query: 479 LPIIIEV 485 LPIIIEV Sbjct: 551 LPIIIEV 557 >C2X0E1.1 C2X0E1_BACCE Zn-dependent hydrolase Length = 557 Score = 706 bits (1822), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/487 (68%), Positives = 404/487 (82%), Gaps = 2/487 (0%) Query: 1 VTHGHEDHIGGIPYFLKQLNIPVYASRLTLGLIQTKLKEHGLLRQTQLNCIDTESTLNFG 60 VTHGHEDHIGGIPYFLKQLN+P+YA++LTLGLI KLKEH L TQL ID+ES + FG Sbjct: 71 VTHGHEDHIGGIPYFLKQLNVPIYATKLTLGLIGIKLKEHKLQDSTQLTIIDSESLIEFG 130 Query: 61 SITITFFRTNHSIPDCLGIVFDTPEGTVVHTGDFKFDMTPVNKQYPDIHKMAAIGEKGVK 120 I ++FF+TNHSIPDCLGI F TPEGTVVHTGDFKFD+TPVN QYPDIHKMA IG GV Sbjct: 131 QINLSFFKTNHSIPDCLGIAFHTPEGTVVHTGDFKFDLTPVNNQYPDIHKMANIGSNGVL 190 Query: 121 FLLSESTNAERPGFTPSERLVGAHLEEAFHKAENRIFISTFASNVHRLQQIVDAAGHTGR 180 LLSESTNAER GFTPSERLVG +EEAF KA ++ ISTFASNV+R+QQIVDAA T R Sbjct: 191 ALLSESTNAERSGFTPSERLVGGKIEEAFIKAHRKVIISTFASNVNRVQQIVDAALKTNR 250 Query: 181 KLALLGRSMVNVVGVAQELGYLNIPEGMLVEPAEAGKMDRGRIAVLCTGSQGEPMAALSR 240 KLALLGRSMVNVV VA E GYLNIPEGML+E E +++ ++A+LCTGSQGEPMAAL+R Sbjct: 251 KLALLGRSMVNVVSVALEQGYLNIPEGMLIEANEINQLEPEKVAILCTGSQGEPMAALAR 310 Query: 241 LANSSHRQLEISEGDTVLLAANPIPGNERNVSRIVDNLYMLGARVIYGSRSE--LHVSGH 298 LA+ ++RQ++I GDTV+L+A+PIPGNERNVSRI+DNL++LGA VIYGS S +HVSGH Sbjct: 311 LASGNYRQVDILPGDTVILSASPIPGNERNVSRIIDNLFLLGANVIYGSGSSTGMHVSGH 370 Query: 299 GSQEELKLMLTLMKPEYFIPIHGEYRMLHHHSMLAEAVGVKNENIFILKNGDIVESNAGD 358 QEELKLMLTLMKP+YFIPIHGE+RMLHHH LAE+VGVK +NI+++ NGD+V+ Sbjct: 371 AYQEELKLMLTLMKPKYFIPIHGEFRMLHHHRQLAESVGVKKDNIYVIGNGDVVDIKNQT 430 Query: 359 VRQSGRITAGQIYVDGLGIGDIGNVVLRDRRQLSADGILITVITLSQNDGRILNDPDTIS 418 Q+ RI AG IYVDGLGIGD+GN +LRDR+QLS DG+L+ VITLS+ + +I++ PDTIS Sbjct: 431 AMQTRRIPAGNIYVDGLGIGDVGNALLRDRKQLSEDGMLVIVITLSKTEEKIISGPDTIS 490 Query: 419 RGFVYVRNSDTLMEEINQLITSTLQKMSAADLGQWNIIKETIKETLGKFLYERTKRRPMI 478 RGFVYVR+S+ +++INQL+ T+ K+ A + QWN++K I+ETLG F+Y TKR+PMI Sbjct: 491 RGFVYVRDSEDFLKKINQLVVETINKLQKAHIYQWNVLKREIRETLGHFIYSHTKRKPMI 550 Query: 479 LPIIIEV 485 LPIIIEV Sbjct: 551 LPIIIEV 557 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.137 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,806,130,956 Number of extensions: 117561194 Number of successful extensions: 328977 Number of sequences better than 1.0e-05: 1395 Number of HSP's gapped: 326139 Number of HSP's successfully gapped: 1396 Length of query: 485 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 345 Effective length of database: 1,741,754,103 Effective search space: 600905165535 Effective search space used: 600905165535 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)