BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0543.0032.p (296 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KKW0.1 B3KKW0_9BACI Pantoate--beta-alanine ligase EC=6.3.2.1 359 1e-97 C0ZCH1.1 C0ZCH1_BREBN Pantoate--beta-alanine ligase EC=6.3.2.1 330 1e-88 B1DM02.1 B1DM02_9BACL Pantoate--beta-alanine ligase EC=6.3.2.1 307 9e-82 B4BFA3.1 B4BFA3_CLOTM Pantoate--beta-alanine ligase EC=6.3.2.1 297 6e-79 A3DDV6.1 PANC_CLOTH Pantothenate synthetase EC=6.3.2.1 297 6e-79 >B3KKW0.1 B3KKW0_9BACI Pantoate--beta-alanine ligase EC=6.3.2.1 Length = 296 Score = 359 bits (922), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 175/290 (60%), Positives = 215/290 (74%) Query: 1 MRVVRTVLELREALDYMRMGGHTPIGFVPTMGYLHEGHASLIRKAGEIANTVVMSIFVNP 60 M+V+R++ +LR L G P+G VPTMGYLHEGHASL+RKA E++ TVV+SIFVNP Sbjct: 1 MKVIRSIADLRPELRDRLGSGRGPVGLVPTMGYLHEGHASLMRKAREMSGTVVISIFVNP 60 Query: 61 LQFGPNEDFSSYPXXXXXXXXXXXXXGADIVFIPGVEEMYPEPIRTKVSVSSLTTQLCGA 120 +QFGP ED+ +YP G D+VFIP VEEMYP+P +TK++V+ +T+ LCGA Sbjct: 61 IQFGPGEDYETYPRDEARDLALAESEGVDVVFIPAVEEMYPQPTKTKIAVAEITSLLCGA 120 Query: 121 SRPGHFDGVTTVVSKLFNMVQPDYAFFGLKDAQQVAVLRRMVSDLNMNVEIIACPIIREE 180 SRPGHFDGVTTVV+KLFN+V+PD+AFFG+KDAQQVAV+ +MV DLNM+V I+ CPIIRE Sbjct: 121 SRPGHFDGVTTVVNKLFNIVKPDFAFFGMKDAQQVAVIEQMVRDLNMDVTIVPCPIIRES 180 Query: 181 DGLALSSRNVYLSGEERTQALVLSRSLRETRKAIEEGTVRTVEEARKLLETVISSSPLAV 240 DGLALSSRNVYL EER QALVLS SLR ++AI +G T E R L IS SPLA Sbjct: 181 DGLALSSRNVYLKPEEREQALVLSGSLRTAQEAIRQGQATTAGEIRAHLRDYISRSPLAD 240 Query: 241 IDYVEILSFPGLETLAGGSLLSDAEGEVIMALAVKFGRTRLIDNNVFIPK 290 IDY E+L+FP L + + D + VIMALAV+FGRTRLIDN + PK Sbjct: 241 IDYAELLTFPELAPVEDSYRIVDEDRTVIMALAVRFGRTRLIDNALLQPK 290 >C0ZCH1.1 C0ZCH1_BREBN Pantoate--beta-alanine ligase EC=6.3.2.1 Length = 288 Score = 330 bits (845), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 166/286 (58%), Positives = 206/286 (72%), Gaps = 7/286 (2%) Query: 1 MRVVRTVLELREALDYMRMGGHTPIGFVPTMGYLHEGHASLIRKAGEIANTVVMSIFVNP 60 M+ V T+ E+R L R G T IG VPTMG+LHEGH SL++ A E+ + VVMSIFVNP Sbjct: 6 MQQVSTIAEMRVHLKDARRQGKT-IGMVPTMGFLHEGHLSLVKAAREVCDLVVMSIFVNP 64 Query: 61 LQFGPNEDFSSYPXXXXXXXXXXXXXGADIVFIPGVEEMYPEPIRTKVSVSSLTTQLCGA 120 LQFGPNEDF YP G D +F P V EMYP P+ T +SV+++TT LCGA Sbjct: 65 LQFGPNEDFERYPRDIERDSKMAEEAGVDFLFTPEVSEMYPTPMLTNISVANVTTPLCGA 124 Query: 121 SRPGHFDGVTTVVSKLFNMVQPDYAFFGLKDAQQVAVLRRMVSDLNMNVEIIACPIIREE 180 SRPGHFDGV+TVV+KLF +VQPDYAFFG KDAQQVAV+ +MV DL+M V+I+ CPI+RE Sbjct: 125 SRPGHFDGVSTVVNKLFQIVQPDYAFFGQKDAQQVAVVTQMVHDLSMPVQIVPCPIVREA 184 Query: 181 DGLALSSRNVYLSGEERTQALVLSRSLRETRKAIEEGTVRTVEEARKLLETVISSSPLAV 240 DGLALSSRNVYLS +ERTQALVLS+SLR+ + + EG + + R + +IS PLA Sbjct: 185 DGLALSSRNVYLSADERTQALVLSQSLRQAEEWLSEGVALSTIKDR--ITQMISEKPLAD 242 Query: 241 IDYVEILSFPGLETLAGGSLLSDAEGEVIMALAVKFGRTRLIDNNV 286 IDYVEILS+P L +A + A +I+ALAV+FG+TRLIDN + Sbjct: 243 IDYVEILSYPALTPMAQET----AGQTIIIALAVRFGKTRLIDNTI 284 >B1DM02.1 B1DM02_9BACL Pantoate--beta-alanine ligase EC=6.3.2.1 Length = 297 Score = 307 bits (786), Expect = 9e-82, Method: Compositional matrix adjust. Identities = 154/290 (53%), Positives = 200/290 (68%), Gaps = 2/290 (0%) Query: 1 MRVVRTVLELR-EALDYMRMGGHTPIGFVPTMGYLHEGHASLIRKAGEIANTVVMSIFVN 59 M + RT+ EL+ E + + + IG VPTMG+LHEGHASL+R++ V+SIFVN Sbjct: 1 MILCRTIAELKNELISIKKSNDNATIGLVPTMGFLHEGHASLMRQSVSENTASVLSIFVN 60 Query: 60 PLQFGPNEDFSSYPXXXXXXXXXXXXXGADIVFIPGVEEMYPEPIRTKVSVSSLTTQLCG 119 P+QFGPNEDF YP G DIVF+P V+EMYP RT V +S LT +LCG Sbjct: 61 PMQFGPNEDFDRYPRDEARDLALAKENGIDIVFMPDVKEMYPSKPRTSVIISQLTDRLCG 120 Query: 120 ASRPGHFDGVTTVVSKLFNMVQPDYAFFGLKDAQQVAVLRRMVSDLNMNVEIIACPIIRE 179 ASRPGHFDGV VVSKLF++VQPD A+FG+KDAQQ+AV+++M DLN+ VEI+ CPI+RE Sbjct: 121 ASRPGHFDGVGLVVSKLFHLVQPDRAYFGMKDAQQLAVIQQMTDDLNIPVEIVPCPIVRE 180 Query: 180 EDGLALSSRNVYLSGEERTQALVLSRSLRETRKAIEEGTVRTVEEARKLLETVISSSPLA 239 DGLALSSRNVYLS E+R QA+VLS+SL + ++E + T EE ++ I+ + A Sbjct: 181 PDGLALSSRNVYLSAEQRQQAVVLSQSLNLAKAWMKEKGI-TPEELLARIKAKINEASQA 239 Query: 240 VIDYVEILSFPGLETLAGGSLLSDAEGEVIMALAVKFGRTRLIDNNVFIP 289 IDY E L++P LE ++ G+ I+ALAVKFG TRLIDN +F+P Sbjct: 240 DIDYAEWLTYPSLELPVRSEPIAAQSGKFILALAVKFGSTRLIDNALFVP 289 >B4BFA3.1 B4BFA3_CLOTM Pantoate--beta-alanine ligase EC=6.3.2.1 Length = 281 Score = 297 bits (761), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 151/284 (53%), Positives = 195/284 (68%), Gaps = 8/284 (2%) Query: 1 MRVVRTVLELREALDYMRMGGHTPIGFVPTMGYLHEGHASLIRKAGEIANTVVMSIFVNP 60 MRV+ T+ +L+ + + G IG VPTMGYLHEGH SL+ + + + VMSIFVNP Sbjct: 1 MRVIETISDLKAIIRTQKNLGRV-IGLVPTMGYLHEGHLSLVNMSRQNNDYTVMSIFVNP 59 Query: 61 LQFGPNEDFSSYPXXXXXXXXXXXXXGADIVFIPGVEEMYPEPIRTKVSVSSLTTQLCGA 120 QFGPNEDF YP G D+VF P V+EMYP+ +T V+V +T LCG Sbjct: 60 TQFGPNEDFDRYPRDLERDLKLAEAAGVDVVFAPSVKEMYPDGYKTYVNVEGITEVLCGK 119 Query: 121 SRPGHFDGVTTVVSKLFNMVQPDYAFFGLKDAQQVAVLRRMVSDLNMNVEIIACPIIREE 180 SRPGHF GVTT+V+KLFN+V+P A+FG KDAQQVAV+++MV DLNMNVEII CPI+REE Sbjct: 120 SRPGHFRGVTTIVTKLFNIVEPHRAYFGQKDAQQVAVIKKMVKDLNMNVEIITCPIVREE 179 Query: 181 DGLALSSRNVYLSGEERTQALVLSRSLRETRKAIEEGTVRTVEEARKLLETVISSSPLAV 240 DGLA+SSRNVYLS EER A++LS+SL E + I++G ++ RK + I + AV Sbjct: 180 DGLAMSSRNVYLSPEERKSAVILSKSLMEAEELIKKGET-DAKKIRKYIIDRIQTEKNAV 238 Query: 241 IDYVEILSFPGLETLAGGSLLSDAEGEVIMALAVKFGRTRLIDN 284 IDYVE+++ LE + + +G V++ALAVKFG TRLIDN Sbjct: 239 IDYVEVVNADTLEN------VDEIKGRVLVALAVKFGSTRLIDN 276 >A3DDV6.1 PANC_CLOTH Pantothenate synthetase EC=6.3.2.1 Length = 281 Score = 297 bits (761), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 151/284 (53%), Positives = 195/284 (68%), Gaps = 8/284 (2%) Query: 1 MRVVRTVLELREALDYMRMGGHTPIGFVPTMGYLHEGHASLIRKAGEIANTVVMSIFVNP 60 MRV+ T+ +L+ + + G IG VPTMGYLHEGH SL+ + + + VMSIFVNP Sbjct: 1 MRVIETISDLKAIIRTQKNLGRV-IGLVPTMGYLHEGHLSLVNMSRQNNDYTVMSIFVNP 59 Query: 61 LQFGPNEDFSSYPXXXXXXXXXXXXXGADIVFIPGVEEMYPEPIRTKVSVSSLTTQLCGA 120 QFGPNEDF YP G D+VF P V+EMYP+ +T V+V +T LCG Sbjct: 60 TQFGPNEDFDRYPRDLERDLKLAEAAGVDVVFAPSVKEMYPDGYKTYVNVEGITEVLCGK 119 Query: 121 SRPGHFDGVTTVVSKLFNMVQPDYAFFGLKDAQQVAVLRRMVSDLNMNVEIIACPIIREE 180 SRPGHF GVTT+V+KLFN+V+P A+FG KDAQQVAV+++MV DLNMNVEII CPI+REE Sbjct: 120 SRPGHFRGVTTIVTKLFNIVEPHRAYFGQKDAQQVAVIKKMVKDLNMNVEIITCPIVREE 179 Query: 181 DGLALSSRNVYLSGEERTQALVLSRSLRETRKAIEEGTVRTVEEARKLLETVISSSPLAV 240 DGLA+SSRNVYLS EER A++LS+SL E + I++G ++ RK + I + AV Sbjct: 180 DGLAMSSRNVYLSPEERKSAVILSKSLMEAEELIKKGET-DAKKIRKYIIDRIQTEKNAV 238 Query: 241 IDYVEILSFPGLETLAGGSLLSDAEGEVIMALAVKFGRTRLIDN 284 IDYVE+++ LE + + +G V++ALAVKFG TRLIDN Sbjct: 239 IDYVEVVNADTLEN------VDEIKGRVLVALAVKFGSTRLIDN 276 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.137 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,534,918,423 Number of extensions: 55691544 Number of successful extensions: 152006 Number of sequences better than 1.0e-05: 1314 Number of HSP's gapped: 150003 Number of HSP's successfully gapped: 1335 Length of query: 296 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 161 Effective length of database: 1,788,859,178 Effective search space: 288006327658 Effective search space used: 288006327658 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 130 (54.7 bits)